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Conserved domains on  [gi|670410892|ref|XP_008646559|]
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agamous-like MADS-box protein AGL80 [Zea mays]

Protein Classification

MADS-box domain-containing protein( domain architecture ID 10083688)

MADS (MCM1, AGAMOUS, DEFICIENS, and SRF, serum response factor)-box domain-containing protein functions as a transcription factor and may be involved in various important aspects of development and differentiation; such as vertebrate serum response factor that binds to the serum response element (SRE), and controls expression of genes that regulate the cytoskeleton during development, morphogenesis and cell migration

CATH:  3.40.1810.10
Gene Ontology:  GO:0003700|GO:0046983
PubMed:  8875863|29802068|12949148
SCOP:  4001594

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
 2-85 7.58e-34

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


:

Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 118.13  E-value: 7.58e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 670410892   2 ARKKVTLQWIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVVYGEEESQPEVWPDvAEAARVLARFKAMPELDQCK 81
Cdd:cd00266    1 GRKKIKIKRIENKKKRAVTFSKRRQGLFKKASELSTLCGAEVAVIVYSPSGKLYVFWPS-SEVEGVISRFEVLSALERKK 79


                 ....
gi 670410892  82 KMMD 85
Cdd:cd00266   80 KAVD 83
 
Name Accession Description Interval E-value
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
 2-85 7.58e-34

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 118.13  E-value: 7.58e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 670410892   2 ARKKVTLQWIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVVYGEEESQPEVWPDvAEAARVLARFKAMPELDQCK 81
Cdd:cd00266    1 GRKKIKIKRIENKKKRAVTFSKRRQGLFKKASELSTLCGAEVAVIVYSPSGKLYVFWPS-SEVEGVISRFEVLSALERKK 79


                 ....
gi 670410892  82 KMMD 85
Cdd:cd00266   80 KAVD 83
MADS smart00432
MADS domain;
3-60 1.00e-20

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 82.99  E-value: 1.00e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 670410892     3 RKKVTLQWIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVVYGEEESQPEVWPD 60
Cdd:smart00432   2 RRKIEIKRIENKTNRQVTFSKRRNGLFKKAHELSVLCDAEVALIVFSPTGKLYEFASP 59
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
10-50 3.51e-19

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 78.62  E-value: 3.51e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 670410892   10 WIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVVYGE 50
Cdd:pfam00319   1 RIENKRARQVTFSKRRKGLFKKASELSVLCGAEVAVIVFSP 41
ARG80 COG5068
Regulator of arginine metabolism and related MADS box-containing transcription factors ...
 1-47 2.12e-04

Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription];


Pssm-ID: 227400 [Multi-domain]  Cd Length: 412  Bit Score: 42.31  E-value: 2.12e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 670410892   1 MARKKVTLQWIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVV 47
Cdd:COG5068   81 VTGRKIGISYITNKTKRSVTFSKRKHGINKKAFELSVLTGTEVLLLV 127
 
Name Accession Description Interval E-value
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
 2-85 7.58e-34

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 118.13  E-value: 7.58e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 670410892   2 ARKKVTLQWIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVVYGEEESQPEVWPDvAEAARVLARFKAMPELDQCK 81
Cdd:cd00266    1 GRKKIKIKRIENKKKRAVTFSKRRQGLFKKASELSTLCGAEVAVIVYSPSGKLYVFWPS-SEVEGVISRFEVLSALERKK 79


                 ....
gi 670410892  82 KMMD 85
Cdd:cd00266   80 KAVD 83
MADS cd00120
MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic ...
 2-59 3.79e-26

MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type II. These subgroups differ mainly in position of the alpha 2 helix responsible for the dimerization interface; Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238067 [Multi-domain]  Cd Length: 59  Bit Score: 97.20  E-value: 3.79e-26
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 670410892   2 ARKKVTLQWIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVVYGEEESQPEVWP 59
Cdd:cd00120    1 GRGKIEIKRIENKTSRQVTFSKRRNGLFKKASELSVLCDAEVAVIVFSPSGKLYEFWS 58
MADS smart00432
MADS domain;
3-60 1.00e-20

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 82.99  E-value: 1.00e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 670410892     3 RKKVTLQWIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVVYGEEESQPEVWPD 60
Cdd:smart00432   2 RRKIEIKRIENKTNRQVTFSKRRNGLFKKAHELSVLCDAEVALIVFSPTGKLYEFASP 59
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
10-50 3.51e-19

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 78.62  E-value: 3.51e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 670410892   10 WIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVVYGE 50
Cdd:pfam00319   1 RIENKRARQVTFSKRRKGLFKKASELSVLCGAEVAVIVFSP 41
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
 2-48 1.75e-14

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 66.81  E-value: 1.75e-14
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 670410892   2 ARKKVTLQWIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVVY 48
Cdd:cd00265    1 GRGKIEIKRIENSTNRQVTFSKRRNGLLKKAHELSVLCDAEVALIIF 47
ARG80 COG5068
Regulator of arginine metabolism and related MADS box-containing transcription factors ...
 1-47 2.12e-04

Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription];


Pssm-ID: 227400 [Multi-domain]  Cd Length: 412  Bit Score: 42.31  E-value: 2.12e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 670410892   1 MARKKVTLQWIANDSTRRATFKKRRKGLMKKASELATLCDVDACVVV 47
Cdd:COG5068   81 VTGRKIGISYITNKTKRSVTFSKRKHGINKKAFELSVLTGTEVLLLV 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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