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Conserved domains on  [gi|665519053|gb|AIF76280|]
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Rep [Bat associated circovirus 9]

Protein Classification

replication-associated family protein( domain architecture ID 10261052)

replication-associated family protein similar to replication-associated protein and Para-Rep C1/7/9, both of which are ATP-dependent helicases

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Viral_Rep super family cl03577
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 15-98 2.60e-23

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


The actual alignment was detected with superfamily member pfam02407:

Pssm-ID: 280553  Cd Length: 82  Bit Score: 91.48  E-value: 2.60e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519053   15 RWCFTINNPTPAEERHLREipvnQVDYLIAGREVGAQGTPHIQGFVNFVKKKTLNQVKLFVGPRAHVEKARGSDEQNRDY 94
Cdd:pfam02407   3 CWCFTLNNPTEFLSLFSQD----ELKYFVYQDERGTTGTKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEEARDY 78


                  ....
gi 665519053   95 CSKD 98
Cdd:pfam02407  79 CMKE 82
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 172-254 5.89e-23

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


:

Pssm-ID: 459992  Cd Length: 102  Bit Score: 91.13  E-value: 5.89e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519053  172 GPPGCGKSKWASEFAD---------PEVTYWKPPRNKWWDGYASHEVVILDDFYGW---LPFDELLRICDRYPLEVEVKG 239
Cdd:pfam00910   5 GPPGCGKSTLAKYLARallkklglpKDSVYSRNPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPYPPPMAA 84

                          90
                  ....*....|....*...
gi 665519053  240 GL---VPFLARTVIITSN 254
Cdd:pfam00910  85 LEekgTPFTSKFVIVTSN 102
 
Name Accession Description Interval E-value
Viral_Rep pfam02407
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 15-98 2.60e-23

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


Pssm-ID: 280553  Cd Length: 82  Bit Score: 91.48  E-value: 2.60e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519053   15 RWCFTINNPTPAEERHLREipvnQVDYLIAGREVGAQGTPHIQGFVNFVKKKTLNQVKLFVGPRAHVEKARGSDEQNRDY 94
Cdd:pfam02407   3 CWCFTLNNPTEFLSLFSQD----ELKYFVYQDERGTTGTKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEEARDY 78


                  ....
gi 665519053   95 CSKD 98
Cdd:pfam02407  79 CMKE 82
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 172-254 5.89e-23

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 91.13  E-value: 5.89e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519053  172 GPPGCGKSKWASEFAD---------PEVTYWKPPRNKWWDGYASHEVVILDDFYGW---LPFDELLRICDRYPLEVEVKG 239
Cdd:pfam00910   5 GPPGCGKSTLAKYLARallkklglpKDSVYSRNPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPYPPPMAA 84

                          90
                  ....*....|....*...
gi 665519053  240 GL---VPFLARTVIITSN 254
Cdd:pfam00910  85 LEekgTPFTSKFVIVTSN 102
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
171-277 3.17e-04

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 41.30  E-value: 3.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519053 171 VGPPGCGKSkW--------ASEfADPEVTYWKPPR--------------NKWWDGYASHEVVILDDFyGWLPFD-----E 223
Cdd:COG1484  105 LGPPGTGKT-HlaialgheACR-AGYRVRFTTAPDlvnelkearadgrlERLLKRLAKVDLLILDEL-GYLPLDaegaeL 181

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 665519053 224 LLR-ICDRYplevevkgglvpfLARTVIITSNKMPQEWYS--SDAVpHAEALYRRIT 277
Cdd:COG1484  182 LFElISDRY-------------ERRSTIITSNLPFSEWGEvfGDPT-LATAILDRLV 224
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 204-277 7.54e-03

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 37.07  E-value: 7.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519053 204 YASHEVVILDDFyGWLPFDE-----LLRIC-DRYplevEvkgglvpflARTVIITSNKMPQEWYS--SDAVpHAEALYRR 275
Cdd:NF038214 149 LARYDLLIIDEL-GYLPFSReganlLFELIaDRY----E---------RGSTIITSNLPFSEWGEvfGDPT-LAAAILDR 213


                 ..
gi 665519053 276 IT 277
Cdd:NF038214 214 LV 215
 
Name Accession Description Interval E-value
Viral_Rep pfam02407
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 15-98 2.60e-23

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


Pssm-ID: 280553  Cd Length: 82  Bit Score: 91.48  E-value: 2.60e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519053   15 RWCFTINNPTPAEERHLREipvnQVDYLIAGREVGAQGTPHIQGFVNFVKKKTLNQVKLFVGPRAHVEKARGSDEQNRDY 94
Cdd:pfam02407   3 CWCFTLNNPTEFLSLFSQD----ELKYFVYQDERGTTGTKHLQGFVEFKNRTSLGQMKKKFPGRAHLEIARGSQEEARDY 78


                  ....
gi 665519053   95 CSKD 98
Cdd:pfam02407  79 CMKE 82
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 172-254 5.89e-23

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 91.13  E-value: 5.89e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519053  172 GPPGCGKSKWASEFAD---------PEVTYWKPPRNKWWDGYASHEVVILDDFYGW---LPFDELLRICDRYPLEVEVKG 239
Cdd:pfam00910   5 GPPGCGKSTLAKYLARallkklglpKDSVYSRNPDDDFWDGYTGQPVVIIDDFGQNpdgPDEAELIRLVSSTPYPPPMAA 84

                          90
                  ....*....|....*...
gi 665519053  240 GL---VPFLARTVIITSN 254
Cdd:pfam00910  85 LEekgTPFTSKFVIVTSN 102
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
171-277 3.17e-04

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 41.30  E-value: 3.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519053 171 VGPPGCGKSkW--------ASEfADPEVTYWKPPR--------------NKWWDGYASHEVVILDDFyGWLPFD-----E 223
Cdd:COG1484  105 LGPPGTGKT-HlaialgheACR-AGYRVRFTTAPDlvnelkearadgrlERLLKRLAKVDLLILDEL-GYLPLDaegaeL 181

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 665519053 224 LLR-ICDRYplevevkgglvpfLARTVIITSNKMPQEWYS--SDAVpHAEALYRRIT 277
Cdd:COG1484  182 LFElISDRY-------------ERRSTIITSNLPFSEWGEvfGDPT-LATAILDRLV 224
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 204-277 7.54e-03

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 37.07  E-value: 7.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519053 204 YASHEVVILDDFyGWLPFDE-----LLRIC-DRYplevEvkgglvpflARTVIITSNKMPQEWYS--SDAVpHAEALYRR 275
Cdd:NF038214 149 LARYDLLIIDEL-GYLPFSReganlLFELIaDRY----E---------RGSTIITSNLPFSEWGEvfGDPT-LAAAILDR 213


                 ..
gi 665519053 276 IT 277
Cdd:NF038214 214 LV 215
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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