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Conserved domains on  [gi|665519022|gb|AIF76264|]
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Rep1 [Rhinolophus associated gemykibivirus 2]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Gemini_AL1 super family cl02967
Geminivirus Rep catalytic domain; The AL1 proteins encodes the replication initiator protein ...
 12-101 1.01e-16

Geminivirus Rep catalytic domain; The AL1 proteins encodes the replication initiator protein (Rep) of geminiviruses, which is a replicon-specific initiator enzyme and is an essential component of the replisome. For geminivirus Rep protein, this N-terminal region is crucial for origin recognition and DNA cleavage and nucleotidyl transfer.


The actual alignment was detected with superfamily member pfam00799:

Pssm-ID: 366313  Cd Length: 113  Bit Score: 72.19  E-value: 1.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519022   12 LTYPQC--GNLDAFDVVD--HLSTLGAECIVGREHHENGGVHLHAFVDFGRKFRSRNVRAFDVDGR------HPNVEPTR 81
Cdd:pfam00799  10 LTYPQCslSKEEALTQIQklQTNTNKKYIKIARELHEDGEPHLHVLLQLEKKFRITDLRFFDIVSPtrsahfHPNIQGAK 89

                          90       100
                  ....*....|....*....|
gi 665519022   82 STPSAGwDYATKDGDIIAGG 101
Cdd:pfam00799  90 SSSDVR-SYVDKDGDTIEWG 108
 
Name Accession Description Interval E-value
Gemini_AL1 pfam00799
Geminivirus Rep catalytic domain; The AL1 proteins encodes the replication initiator protein ...
 12-101 1.01e-16

Geminivirus Rep catalytic domain; The AL1 proteins encodes the replication initiator protein (Rep) of geminiviruses, which is a replicon-specific initiator enzyme and is an essential component of the replisome. For geminivirus Rep protein, this N-terminal region is crucial for origin recognition and DNA cleavage and nucleotidyl transfer.


Pssm-ID: 366313  Cd Length: 113  Bit Score: 72.19  E-value: 1.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519022   12 LTYPQC--GNLDAFDVVD--HLSTLGAECIVGREHHENGGVHLHAFVDFGRKFRSRNVRAFDVDGR------HPNVEPTR 81
Cdd:pfam00799  10 LTYPQCslSKEEALTQIQklQTNTNKKYIKIARELHEDGEPHLHVLLQLEKKFRITDLRFFDIVSPtrsahfHPNIQGAK 89

                          90       100
                  ....*....|....*....|
gi 665519022   82 STPSAGwDYATKDGDIIAGG 101
Cdd:pfam00799  90 SSSDVR-SYVDKDGDTIEWG 108
 
Name Accession Description Interval E-value
Gemini_AL1 pfam00799
Geminivirus Rep catalytic domain; The AL1 proteins encodes the replication initiator protein ...
 12-101 1.01e-16

Geminivirus Rep catalytic domain; The AL1 proteins encodes the replication initiator protein (Rep) of geminiviruses, which is a replicon-specific initiator enzyme and is an essential component of the replisome. For geminivirus Rep protein, this N-terminal region is crucial for origin recognition and DNA cleavage and nucleotidyl transfer.


Pssm-ID: 366313  Cd Length: 113  Bit Score: 72.19  E-value: 1.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665519022   12 LTYPQC--GNLDAFDVVD--HLSTLGAECIVGREHHENGGVHLHAFVDFGRKFRSRNVRAFDVDGR------HPNVEPTR 81
Cdd:pfam00799  10 LTYPQCslSKEEALTQIQklQTNTNKKYIKIARELHEDGEPHLHVLLQLEKKFRITDLRFFDIVSPtrsahfHPNIQGAK 89

                          90       100
                  ....*....|....*....|
gi 665519022   82 STPSAGwDYATKDGDIIAGG 101
Cdd:pfam00799  90 SSSDVR-SYVDKDGDTIEWG 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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