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Conserved domains on  [gi|663513256|gb|AIF03800|]
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hypothetical protein [uncultured marine group II/III euryarchaeote KM3_169_H09]

Protein Classification

AAA family ATPase( domain architecture ID 1003843)

AAA family ATPase containing an AAA (ATPases Associated with various cellular Activities) domain, may function as an ATP-dependent endonuclease or the ATPase component of an ABC-type transporter; similar to Bacillus subtilis protein YhaN

CATH:  3.40.50.300
Gene Ontology:  GO:0005524|GO:0016887
PubMed:  15037234|18208389|16828312|18466635|15037233

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
743-1065 5.76e-37

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


:

Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 148.76  E-value: 5.76e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  743 YAEQLERAKKAIEARGKHDDLERQLidkrprakrrntKKRGLEDEATDLLASFKLGSDDEMGSAVGTGKHRLNLEGEMEN 822
Cdd:COG4717   339 LLELLDRIEELQELLREAEELEEEL------------QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEE 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  823 ERGQFTNLAKrwdkswnDFENEIEGADPIEDEAICTEKNRRDESLGEEIADLQGQLDSLSAELLNLDESDELTRKQADKK 902
Cdd:COG4717   407 LEEQLEELLG-------ELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELE 479

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  903 AILAELNEVNLRWAHLFLVRFIIQRTREQYEGSHGSEVLIRASEHLERITGGRYTQIlRVVEDPGYQLVEASGSYRSpiP 982
Cdd:COG4717   480 ELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERASEYFSRLTDGRYRLI-RIDEDLSLKVDTEDGRTRP--V 556

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  983 PDLSRAAFAQVYLCIRLAYAEKGTHSSLPIILDDAYEGYDDERVPPALDILCELGKARQVILLSHHGHICEAAEERGASV 1062
Cdd:COG4717   557 EELSRGTREQLYLALRLALAELLAGEPLPLILDDAFVNFDDERLRAALELLAELAKGRQVIYFTCHEELVELFQEEGAHV 636


                  ...
gi 663513256 1063 IQL 1065
Cdd:COG4717   637 IEL 639
AAA_27 super family cl38415
AAA domain; This domain is found in a number of double-strand DNA break proteins. This domain ...
 2-212 4.61e-15

AAA domain; This domain is found in a number of double-strand DNA break proteins. This domain contains a P-loop motif.


The actual alignment was detected with superfamily member pfam13514:

Pssm-ID: 433272 [Multi-domain]  Cd Length: 207  Bit Score: 75.28  E-value: 4.61e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256     2 MRIDTIHVDKYGGLNDLTLQLVN---DFQVIKGLNEEGKTTLLAFIRGVFFGFSK------VFPHLKMrsapfftegeRM 72
Cdd:pfam13514    1 MRIRRLDLERYGPFTDRSLDFPAggpDLHLIYGPNEAGKSTALRAISDLLFGIPLrtpynfLHDYSDL----------RI 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256    73 GGRIEvmvelEGKERRYAIIRHTGTKQDgelsIRDLESNGLivgGEAVTLRdiILGGVDKTLFDSVFVLTVDDL----HD 148
Cdd:pfam13514   71 GATLE-----NADGETLEFRRRKGRKNT----LLDADGQPL---PDDVLAP--FLGGLDRETFERMFGLDHERLreggEA 136

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663513256   149 LkALSKDEVAHALFSADSGLGlELPRELSAMQEQMDKLYNdEHKRGKQRQRILTARLNGLTKEI 212
Cdd:pfam13514  137 I-LEAEGDLGQALFAAGSGLA-GLRRVLEALDAEADALFK-PRGSSPRAFNQALARLDEAQREL 197
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 199-759 6.82e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 6.82e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  199 RILTARLNGLTKEIGTLNQKMKELSGRRGAREKmngQLEELRRTRSGLALDVKRATDRInaREHKSRIDGLKEEIDELPD 278
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEA---ELEELRLELEELELELEEAQAEE--YELLAELARLEQDIARLEE 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  279 GpfpADSAQARLESLRKDISSLEDELGDLDEEIESLENEQSnlsldpDAEGSHSSLEAVRVSDLFERVTEVEHANNLRDE 358
Cdd:COG1196   310 R---RRELEERLEELEEELAELEEELEELEEELEELEEELE------EAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  359 KESLSDLELEEgfETRLKEAHSRHEEIVGKIEDLTEREDIANISLGKYEPQVLDAGLASEidgAITRRYSQHSDPLDRAK 438
Cdd:COG1196   381 LEELAEELLEA--LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE---EEEEALEEAAEEEAELE 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  439 GEVKRIESDLKAALKSAGGMDAEVLDDLPLDAASISRLRASLSESGSTP-RSRFAQIQTLIALSALVLGLCIAFVLDEML 517
Cdd:COG1196   456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  518 GGGGLALISLLLLILDRLENQGAEGAAELSGSVKKQLK----HLGLSSHASAKDLDRLVNSLSGAITHSEELSRAKSSRD 593
Cdd:COG1196   536 YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARY 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  594 EVEGLYTAGIELLNRLVDDCGLEAVDEGASAAHLEGVLEDIMLTHRYAVIQVGVQNEELTKIHTSKGIFSGQLRDNTKEL 673
Cdd:COG1196   616 YVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELEL 695

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  674 NDILAELDEEDQESATAVLAEITRRLEIETELERLASAESVVEKIREAVNAACKSVGDGEPSLDNLAIVYAEQLERAKKA 753
Cdd:COG1196   696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775


                  ....*.
gi 663513256  754 IEARGK 759
Cdd:COG1196   776 IEALGP 781
 
Name Accession Description Interval E-value
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
743-1065 5.76e-37

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 148.76  E-value: 5.76e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  743 YAEQLERAKKAIEARGKHDDLERQLidkrprakrrntKKRGLEDEATDLLASFKLGSDDEMGSAVGTGKHRLNLEGEMEN 822
Cdd:COG4717   339 LLELLDRIEELQELLREAEELEEEL------------QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEE 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  823 ERGQFTNLAKrwdkswnDFENEIEGADPIEDEAICTEKNRRDESLGEEIADLQGQLDSLSAELLNLDESDELTRKQADKK 902
Cdd:COG4717   407 LEEQLEELLG-------ELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELE 479

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  903 AILAELNEVNLRWAHLFLVRFIIQRTREQYEGSHGSEVLIRASEHLERITGGRYTQIlRVVEDPGYQLVEASGSYRSpiP 982
Cdd:COG4717   480 ELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERASEYFSRLTDGRYRLI-RIDEDLSLKVDTEDGRTRP--V 556

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  983 PDLSRAAFAQVYLCIRLAYAEKGTHSSLPIILDDAYEGYDDERVPPALDILCELGKARQVILLSHHGHICEAAEERGASV 1062
Cdd:COG4717   557 EELSRGTREQLYLALRLALAELLAGEPLPLILDDAFVNFDDERLRAALELLAELAKGRQVIYFTCHEELVELFQEEGAHV 636


                  ...
gi 663513256 1063 IQL 1065
Cdd:COG4717   637 IEL 639
AAA_27 pfam13514
AAA domain; This domain is found in a number of double-strand DNA break proteins. This domain ...
 2-212 4.61e-15

AAA domain; This domain is found in a number of double-strand DNA break proteins. This domain contains a P-loop motif.


Pssm-ID: 433272 [Multi-domain]  Cd Length: 207  Bit Score: 75.28  E-value: 4.61e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256     2 MRIDTIHVDKYGGLNDLTLQLVN---DFQVIKGLNEEGKTTLLAFIRGVFFGFSK------VFPHLKMrsapfftegeRM 72
Cdd:pfam13514    1 MRIRRLDLERYGPFTDRSLDFPAggpDLHLIYGPNEAGKSTALRAISDLLFGIPLrtpynfLHDYSDL----------RI 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256    73 GGRIEvmvelEGKERRYAIIRHTGTKQDgelsIRDLESNGLivgGEAVTLRdiILGGVDKTLFDSVFVLTVDDL----HD 148
Cdd:pfam13514   71 GATLE-----NADGETLEFRRRKGRKNT----LLDADGQPL---PDDVLAP--FLGGLDRETFERMFGLDHERLreggEA 136

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663513256   149 LkALSKDEVAHALFSADSGLGlELPRELSAMQEQMDKLYNdEHKRGKQRQRILTARLNGLTKEI 212
Cdd:pfam13514  137 I-LEAEGDLGQALFAAGSGLA-GLRRVLEALDAEADALFK-PRGSSPRAFNQALARLDEAQREL 197
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 199-759 6.82e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 6.82e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  199 RILTARLNGLTKEIGTLNQKMKELSGRRGAREKmngQLEELRRTRSGLALDVKRATDRInaREHKSRIDGLKEEIDELPD 278
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEA---ELEELRLELEELELELEEAQAEE--YELLAELARLEQDIARLEE 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  279 GpfpADSAQARLESLRKDISSLEDELGDLDEEIESLENEQSnlsldpDAEGSHSSLEAVRVSDLFERVTEVEHANNLRDE 358
Cdd:COG1196   310 R---RRELEERLEELEEELAELEEELEELEEELEELEEELE------EAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  359 KESLSDLELEEgfETRLKEAHSRHEEIVGKIEDLTEREDIANISLGKYEPQVLDAGLASEidgAITRRYSQHSDPLDRAK 438
Cdd:COG1196   381 LEELAEELLEA--LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE---EEEEALEEAAEEEAELE 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  439 GEVKRIESDLKAALKSAGGMDAEVLDDLPLDAASISRLRASLSESGSTP-RSRFAQIQTLIALSALVLGLCIAFVLDEML 517
Cdd:COG1196   456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  518 GGGGLALISLLLLILDRLENQGAEGAAELSGSVKKQLK----HLGLSSHASAKDLDRLVNSLSGAITHSEELSRAKSSRD 593
Cdd:COG1196   536 YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARY 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  594 EVEGLYTAGIELLNRLVDDCGLEAVDEGASAAHLEGVLEDIMLTHRYAVIQVGVQNEELTKIHTSKGIFSGQLRDNTKEL 673
Cdd:COG1196   616 YVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELEL 695

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  674 NDILAELDEEDQESATAVLAEITRRLEIETELERLASAESVVEKIREAVNAACKSVGDGEPSLDNLAIVYAEQLERAKKA 753
Cdd:COG1196   696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775


                  ....*.
gi 663513256  754 IEARGK 759
Cdd:COG1196   776 IEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 171-913 1.57e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 1.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   171 ELPRELSAMQEQMDKLyNDEHKRGKQRQRILTARLNGLTKEIGTLNQKMKELSGRRGA----REKMNGQLEELRRTRSGL 246
Cdd:TIGR02168  257 ELTAELQELEEKLEEL-RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANlerqLEELEAQLEELESKLDEL 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   247 ALDVKRATDRINarEHKSRIDGLKEEIDELPDGPFPADSA----QARLESLRKDISSLEDELGDLDEEIESLENEQSNLS 322
Cdd:TIGR02168  336 AEELAELEEKLE--ELKEELESLEAELEELEAELEELESRleelEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   323 -----LDPDAEGSHSSLEAVRVSDLFERVTEVEhannlrdeKESLSDLELEEGFETRLKEAHSRHEEIVGKIEDLteRED 397
Cdd:TIGR02168  414 drrerLQQEIEELLKKLEEAELKELQAELEELE--------EELEELQEELERLEEALEELREELEEAEQALDAA--ERE 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   398 IANISLGKYEPQVLDAGLASEIDG--AITRRYSQHSDPLDRAkGEVKRIESDLKAALKSAGG--MDAEVLDDLPLDAASI 473
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLEGFSEGvkALLKNQSGLSGILGVL-SELISVDEGYEAAIEAALGgrLQAVVVENLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   474 SRL------RASLSE----SGSTPRSRFAQIqtlIALSALVLGLCIAFVLDEMLGGGGLALISLLLLILDRLENqgaegA 543
Cdd:TIGR02168  563 AFLkqnelgRVTFLPldsiKGTEIQGNDREI---LKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDN-----A 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   544 AELSGSVKKQ----------LKHLGLSSHASAKdldrlvnSLSGAITHSEELSRAKSSRDEVEGLYTAGIELLNRLvddc 613
Cdd:TIGR02168  635 LELAKKLRPGyrivtldgdlVRPGGVITGGSAK-------TNSSILERRREIEELEEKIEELEEKIAELEKALAEL---- 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   614 gLEAVDEgasaahLEGVLEDIMLTHRYAVIQVGVQNEELTKIHTSKGIFSGQLRDNTKELNDILAELDEEDQESATAVLA 693
Cdd:TIGR02168  704 -RKELEE------LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   694 EITRRLEIETELERLASAESVVEKIREAVNAACKSVGDGEPSLDNLAIVYaEQLERAKKAIEARgkHDDLERQLIDKRPR 773
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL-ESLERRIAATERR--LEDLEEQIEELSED 853

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   774 AKRRNTKKRGLEDEATDLLASFKLGSDDEMGSAVGTGKHRLNLE------GEMENERGQFTNLAKRWDKSWNDFENEIEG 847
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEelseelRELESKRSELRRELEELREKLAQLELRLEG 933

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 663513256   848 AdpiedeaicteKNRRD---ESLGEEIADLQGQLDSLSAELLnlDESDELTRKQADKKAILAELNEVNL 913
Cdd:TIGR02168  934 L-----------EVRIDnlqERLSEEYSLTLEEAEALENKIE--DDEEEARRRLKRLENKIKELGPVNL 989
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2-287 4.35e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 4.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256    2 MRIDTIHVDKYGGLNDLTLQLVNDFQVIKGLNEEGKTTLLAFIRGVFFgfSKVFPHLKMRSAPFFTEGERMGGRIEV--- 78
Cdd:COG4717     1 MKIKELEIYGFGKFRDRTIEFSPGLNVIYGPNEAGKSTLLAFIRAMLL--ERLEKEADELFKPQGRKPELNLKELKElee 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   79 -MVELEGKERRYAiiRHTGTKQDGELSIRDLESnglivggEAVTLRdiilggvdktlfdsvfvltvddlHDLKALSKDEV 157
Cdd:COG4717    79 eLKEAEEKEEEYA--ELQEELEELEEELEELEA-------ELEELR-----------------------EELEKLEKLLQ 126

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  158 AHALFSADSglglELPRELSAMQEQMDKLYNDEHKRGKQRQRILTarlngLTKEIGTLNQKMKELsgRRGAREKMNGQLE 237
Cdd:COG4717   127 LLPLYQELE----ALEAELAELPERLEELEERLEELRELEEELEE-----LEAELAELQEELEEL--LEQLSLATEEELQ 195

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 663513256  238 ELRRTRSGLALDVKRATDRInaREHKSRIDGLKEEIDELPDGPFPADSAQ 287
Cdd:COG4717   196 DLAEELEELQQRLAELEEEL--EEAQEELEELEEELEQLENELEAAALEE 243
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
171-395 9.78e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 9.78e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  171 ELPRELSAMQEQMDKLYNDEHKRGKQRQRILTARLNGLTKEIGTLNQKMKELSGRRGAREKMNGQLEELRRTRSGLaldv 250
Cdd:PRK03918  500 ELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAEL---- 575

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  251 kratDRINAREHKSRIDGLKEEIDELPdgPF-----PADSAQARLESLRKDISSLEDELGDLDEEIESLENEQSNLSldp 325
Cdd:PRK03918  576 ----LKELEELGFESVEELEERLKELE--PFyneylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELR--- 646

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  326 daegshssleaVRVSDLFERVTEVEHAnNLRDEKESLSdlELEEGFETRLKEAHSRHEEIVGKIEDLTER 395
Cdd:PRK03918  647 -----------KELEELEKKYSEEEYE-ELREEYLELS--RELAGLRAELEELEKRREEIKKTLEKLKEE 702
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 672-970 4.23e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.20  E-value: 4.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   672 ELNDILAELDEEdQESATAVLAEITRRL-EIETELERLASAESVVEKIREAVNAACKSvgdgepsLDNLAIVYAEQLERA 750
Cdd:TIGR02168  271 ELRLEVSELEEE-IEELQKELYALANEIsRLEQQKQILRERLANLERQLEELEAQLEE-------LESKLDELAEELAEL 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   751 KKAI-EARGKHDDLERQLIDKRPRAKRRNTKKRGLEDEATDLLASFKLgsddemgsavgtgkhrlnLEGEMENERGQFTN 829
Cdd:TIGR02168  343 EEKLeELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ------------------LELQIASLNNEIER 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   830 LAKR---WDKSWNDFENEIEGADPIEDEAICTEKNRRDESLGEEIADLQGQLDSLSAELLNLDEsdELTRKQADKKAILA 906
Cdd:TIGR02168  405 LEARlerLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE--ELEEAEQALDAAER 482

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663513256   907 ELNEVNLRWAHLflvrfiiQRTREQYEGSHGSEVLIRASEHLERITGGRYTQILRVveDPGYQL 970
Cdd:TIGR02168  483 ELAQLQARLDSL-------ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISV--DEGYEA 537
 
Name Accession Description Interval E-value
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
743-1065 5.76e-37

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 148.76  E-value: 5.76e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  743 YAEQLERAKKAIEARGKHDDLERQLidkrprakrrntKKRGLEDEATDLLASFKLGSDDEMGSAVGTGKHRLNLEGEMEN 822
Cdd:COG4717   339 LLELLDRIEELQELLREAEELEEEL------------QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEE 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  823 ERGQFTNLAKrwdkswnDFENEIEGADPIEDEAICTEKNRRDESLGEEIADLQGQLDSLSAELLNLDESDELTRKQADKK 902
Cdd:COG4717   407 LEEQLEELLG-------ELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELE 479

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  903 AILAELNEVNLRWAHLFLVRFIIQRTREQYEGSHGSEVLIRASEHLERITGGRYTQIlRVVEDPGYQLVEASGSYRSpiP 982
Cdd:COG4717   480 ELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERASEYFSRLTDGRYRLI-RIDEDLSLKVDTEDGRTRP--V 556

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  983 PDLSRAAFAQVYLCIRLAYAEKGTHSSLPIILDDAYEGYDDERVPPALDILCELGKARQVILLSHHGHICEAAEERGASV 1062
Cdd:COG4717   557 EELSRGTREQLYLALRLALAELLAGEPLPLILDDAFVNFDDERLRAALELLAELAKGRQVIYFTCHEELVELFQEEGAHV 636


                  ...
gi 663513256 1063 IQL 1065
Cdd:COG4717   637 IEL 639
AAA_27 pfam13514
AAA domain; This domain is found in a number of double-strand DNA break proteins. This domain ...
 2-212 4.61e-15

AAA domain; This domain is found in a number of double-strand DNA break proteins. This domain contains a P-loop motif.


Pssm-ID: 433272 [Multi-domain]  Cd Length: 207  Bit Score: 75.28  E-value: 4.61e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256     2 MRIDTIHVDKYGGLNDLTLQLVN---DFQVIKGLNEEGKTTLLAFIRGVFFGFSK------VFPHLKMrsapfftegeRM 72
Cdd:pfam13514    1 MRIRRLDLERYGPFTDRSLDFPAggpDLHLIYGPNEAGKSTALRAISDLLFGIPLrtpynfLHDYSDL----------RI 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256    73 GGRIEvmvelEGKERRYAIIRHTGTKQDgelsIRDLESNGLivgGEAVTLRdiILGGVDKTLFDSVFVLTVDDL----HD 148
Cdd:pfam13514   71 GATLE-----NADGETLEFRRRKGRKNT----LLDADGQPL---PDDVLAP--FLGGLDRETFERMFGLDHERLreggEA 136

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663513256   149 LkALSKDEVAHALFSADSGLGlELPRELSAMQEQMDKLYNdEHKRGKQRQRILTARLNGLTKEI 212
Cdd:pfam13514  137 I-LEAEGDLGQALFAAGSGLA-GLRRVLEALDAEADALFK-PRGSSPRAFNQALARLDEAQREL 197
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 199-759 6.82e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 6.82e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  199 RILTARLNGLTKEIGTLNQKMKELSGRRGAREKmngQLEELRRTRSGLALDVKRATDRInaREHKSRIDGLKEEIDELPD 278
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEA---ELEELRLELEELELELEEAQAEE--YELLAELARLEQDIARLEE 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  279 GpfpADSAQARLESLRKDISSLEDELGDLDEEIESLENEQSnlsldpDAEGSHSSLEAVRVSDLFERVTEVEHANNLRDE 358
Cdd:COG1196   310 R---RRELEERLEELEEELAELEEELEELEEELEELEEELE------EAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  359 KESLSDLELEEgfETRLKEAHSRHEEIVGKIEDLTEREDIANISLGKYEPQVLDAGLASEidgAITRRYSQHSDPLDRAK 438
Cdd:COG1196   381 LEELAEELLEA--LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE---EEEEALEEAAEEEAELE 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  439 GEVKRIESDLKAALKSAGGMDAEVLDDLPLDAASISRLRASLSESGSTP-RSRFAQIQTLIALSALVLGLCIAFVLDEML 517
Cdd:COG1196   456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  518 GGGGLALISLLLLILDRLENQGAEGAAELSGSVKKQLK----HLGLSSHASAKDLDRLVNSLSGAITHSEELSRAKSSRD 593
Cdd:COG1196   536 YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARY 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  594 EVEGLYTAGIELLNRLVDDCGLEAVDEGASAAHLEGVLEDIMLTHRYAVIQVGVQNEELTKIHTSKGIFSGQLRDNTKEL 673
Cdd:COG1196   616 YVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELEL 695

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  674 NDILAELDEEDQESATAVLAEITRRLEIETELERLASAESVVEKIREAVNAACKSVGDGEPSLDNLAIVYAEQLERAKKA 753
Cdd:COG1196   696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775


                  ....*.
gi 663513256  754 IEARGK 759
Cdd:COG1196   776 IEALGP 781
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
202-395 6.97e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.31  E-value: 6.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  202 TARLNGLTKEIGTLNQKMKELSGRRgarEKMNGQLEELRRTRSGLALDVKRATDRINAREHKSRIDGLKEEIDELPDGPF 281
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERL---EALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSD 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  282 PADSAQARLESLRKDISSLEDELGDLDEEIESLENEQSNL-SLDPDAEGSHSSLEAVRVSDLFERVTEVeHANNLRDEKE 360
Cdd:COG4913   686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAeEELDELQDRLEAAEDLARLELRALLEER-FAAALGDAVE 764

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 663513256  361 SlsdlELEEGFETRLKEAHSRHEEIVGKIEDLTER 395
Cdd:COG4913   765 R----ELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 171-913 1.57e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 1.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   171 ELPRELSAMQEQMDKLyNDEHKRGKQRQRILTARLNGLTKEIGTLNQKMKELSGRRGA----REKMNGQLEELRRTRSGL 246
Cdd:TIGR02168  257 ELTAELQELEEKLEEL-RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANlerqLEELEAQLEELESKLDEL 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   247 ALDVKRATDRINarEHKSRIDGLKEEIDELPDGPFPADSA----QARLESLRKDISSLEDELGDLDEEIESLENEQSNLS 322
Cdd:TIGR02168  336 AEELAELEEKLE--ELKEELESLEAELEELEAELEELESRleelEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   323 -----LDPDAEGSHSSLEAVRVSDLFERVTEVEhannlrdeKESLSDLELEEGFETRLKEAHSRHEEIVGKIEDLteRED 397
Cdd:TIGR02168  414 drrerLQQEIEELLKKLEEAELKELQAELEELE--------EELEELQEELERLEEALEELREELEEAEQALDAA--ERE 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   398 IANISLGKYEPQVLDAGLASEIDG--AITRRYSQHSDPLDRAkGEVKRIESDLKAALKSAGG--MDAEVLDDLPLDAASI 473
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLEGFSEGvkALLKNQSGLSGILGVL-SELISVDEGYEAAIEAALGgrLQAVVVENLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   474 SRL------RASLSE----SGSTPRSRFAQIqtlIALSALVLGLCIAFVLDEMLGGGGLALISLLLLILDRLENqgaegA 543
Cdd:TIGR02168  563 AFLkqnelgRVTFLPldsiKGTEIQGNDREI---LKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDN-----A 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   544 AELSGSVKKQ----------LKHLGLSSHASAKdldrlvnSLSGAITHSEELSRAKSSRDEVEGLYTAGIELLNRLvddc 613
Cdd:TIGR02168  635 LELAKKLRPGyrivtldgdlVRPGGVITGGSAK-------TNSSILERRREIEELEEKIEELEEKIAELEKALAEL---- 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   614 gLEAVDEgasaahLEGVLEDIMLTHRYAVIQVGVQNEELTKIHTSKGIFSGQLRDNTKELNDILAELDEEDQESATAVLA 693
Cdd:TIGR02168  704 -RKELEE------LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   694 EITRRLEIETELERLASAESVVEKIREAVNAACKSVGDGEPSLDNLAIVYaEQLERAKKAIEARgkHDDLERQLIDKRPR 773
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL-ESLERRIAATERR--LEDLEEQIEELSED 853

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   774 AKRRNTKKRGLEDEATDLLASFKLGSDDEMGSAVGTGKHRLNLE------GEMENERGQFTNLAKRWDKSWNDFENEIEG 847
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEelseelRELESKRSELRRELEELREKLAQLELRLEG 933

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 663513256   848 AdpiedeaicteKNRRD---ESLGEEIADLQGQLDSLSAELLnlDESDELTRKQADKKAILAELNEVNL 913
Cdd:TIGR02168  934 L-----------EVRIDnlqERLSEEYSLTLEEAEALENKIE--DDEEEARRRLKRLENKIKELGPVNL 989
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 170-392 1.73e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 1.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   170 LELPRELSAMQEQMDKLYnDEHKRGKQRQRILTARLNGLTKEIGTLnqkMKELSGRRGAREKMNGQLEELRRTRSglALD 249
Cdd:TIGR02169  677 QRLRERLEGLKRELSSLQ-SELRRIENRLDELSQELSDASRKIGEI---EKEIEQLEQEEEKLKERLEELEEDLS--SLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   250 VKRATDRINAREHKSRIDGLKEEIDELPD--GPFPADSAQARLESLRKDISSLEDELGDLDEEIESLENEQSNLSLDPDA 327
Cdd:TIGR02169  751 QEIENVKSELKELEARIEELEEDLHKLEEalNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEY 830

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 663513256   328 EGSHSSLEAVRVSDLFERVTEVEHA-NNLRDEKESLsDLELEEgFETRLKEAHSRHEEIVGKIEDL 392
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEKEiENLNGKKEEL-EEELEE-LEAALRDLESRLGDLKKERDEL 894
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2-287 4.35e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 4.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256    2 MRIDTIHVDKYGGLNDLTLQLVNDFQVIKGLNEEGKTTLLAFIRGVFFgfSKVFPHLKMRSAPFFTEGERMGGRIEV--- 78
Cdd:COG4717     1 MKIKELEIYGFGKFRDRTIEFSPGLNVIYGPNEAGKSTLLAFIRAMLL--ERLEKEADELFKPQGRKPELNLKELKElee 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   79 -MVELEGKERRYAiiRHTGTKQDGELSIRDLESnglivggEAVTLRdiilggvdktlfdsvfvltvddlHDLKALSKDEV 157
Cdd:COG4717    79 eLKEAEEKEEEYA--ELQEELEELEEELEELEA-------ELEELR-----------------------EELEKLEKLLQ 126

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  158 AHALFSADSglglELPRELSAMQEQMDKLYNDEHKRGKQRQRILTarlngLTKEIGTLNQKMKELsgRRGAREKMNGQLE 237
Cdd:COG4717   127 LLPLYQELE----ALEAELAELPERLEELEERLEELRELEEELEE-----LEAELAELQEELEEL--LEQLSLATEEELQ 195

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 663513256  238 ELRRTRSGLALDVKRATDRInaREHKSRIDGLKEEIDELPDGPFPADSAQ 287
Cdd:COG4717   196 DLAEELEELQQRLAELEEEL--EEAQEELEELEEELEQLENELEAAALEE 243
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
171-395 9.78e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 9.78e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  171 ELPRELSAMQEQMDKLYNDEHKRGKQRQRILTARLNGLTKEIGTLNQKMKELSGRRGAREKMNGQLEELRRTRSGLaldv 250
Cdd:PRK03918  500 ELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAEL---- 575

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  251 kratDRINAREHKSRIDGLKEEIDELPdgPF-----PADSAQARLESLRKDISSLEDELGDLDEEIESLENEQSNLSldp 325
Cdd:PRK03918  576 ----LKELEELGFESVEELEERLKELE--PFyneylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELR--- 646

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  326 daegshssleaVRVSDLFERVTEVEHAnNLRDEKESLSdlELEEGFETRLKEAHSRHEEIVGKIEDLTER 395
Cdd:PRK03918  647 -----------KELEELEKKYSEEEYE-ELREEYLELS--RELAGLRAELEELEKRREEIKKTLEKLKEE 702
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 178-321 2.51e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.84  E-value: 2.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  178 AMQEQMDKLYndehkrgkQRQRILTaRLNGLTKEIGTL----NQKMKELSGRRGAREKMNGQLEELRRTRSGLALDVKRA 253
Cdd:COG1579     1 AMPEDLRALL--------DLQELDS-ELDRLEHRLKELpaelAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEV 71

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  254 TDRInaREHKSRIDGLK--EEIDELpdgpfpadsaQARLESLRKDISSLEDELGDLDEEIESLENEQSNL 321
Cdd:COG1579    72 EARI--KKYEEQLGNVRnnKEYEAL----------QKEIESLKRRISDLEDEILELMERIEELEEELAEL 129
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 171-376 2.63e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 2.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   171 ELPRELSAMQEQMDKLYNDEhkrGKQRQRILTARLNGLTKEIGTLNQKMKELSGRRGAREKMNGQLEELRRTRSGLALDV 250
Cdd:TIGR02169  769 ELEEDLHKLEEALNDLEARL---SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   251 KratDRINAREhkSRIDGLKEEIDELpdgpfpadsaQARLESLRKDISSLEDELGDLDEEIESLENEQSN-------LSL 323
Cdd:TIGR02169  846 K---EQIKSIE--KEIENLNGKKEEL----------EEELEELEAALRDLESRLGDLKKERDELEAQLRElerkieeLEA 910

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 663513256   324 DPDAEGSHSSLEAVRVSDLFERVTEVEhANNLRDEKESLSDLELEEGFETRLK 376
Cdd:TIGR02169  911 QIEKKRKRLSELKAKLEALEEELSEIE-DPKGEDEEIPEEELSLEDVQAELQR 962
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 171-801 3.47e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.14  E-value: 3.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   171 ELPRELSAMQEQMDKLYNDEHKRGKQRQRIlTARLNGLTKEIGTLNQKMKELSGRRGAR-----EKMNGQLEELRRTRSG 245
Cdd:TIGR02169  234 ALERQKEAIERQLASLEEELEKLTEEISEL-EKRLEEIEQLLEELNKKIKDLGEEEQLRvkekiGELEAEIASLERSIAE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   246 LALDVKRATDRInaREHKSRIDGLKEEIDELpdgpfpadsaQARLESLRKDISSLEDELGDLDEEIESLENEQSNLSLDP 325
Cdd:TIGR02169  313 KERELEDAEERL--AKLEAEIDKLLAEIEEL----------EREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   326 DAEGSHSSLEAVRVSDLFERVTEVE-HANNLRDEKESLS----DLELE-EGFETRLKEAHSRHEEIVGKIEDLTEREDIA 399
Cdd:TIGR02169  381 AETRDELKDYREKLEKLKREINELKrELDRLQEELQRLSeelaDLNAAiAGIEAKINELEEEKEDKALEIKKQEWKLEQL 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   400 NISLGKYEPQVLD------------AGLASEIDGA-ITRRYSQHSDPLDRAKGEVK---------------RIESDLKAA 451
Cdd:TIGR02169  461 AADLSKYEQELYDlkeeydrvekelSKLQRELAEAeAQARASEERVRGGRAVEEVLkasiqgvhgtvaqlgSVGERYATA 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   452 LKSAGG--MDAEVLDDLPLDAASISRLRA-SLSESGSTPRSRFAQIQTLiaLSALVLGLCIAFVLDEM------------ 516
Cdd:TIGR02169  541 IEVAAGnrLNNVVVEDDAVAKEAIELLKRrKAGRATFLPLNKMRDERRD--LSILSEDGVIGFAVDLVefdpkyepafky 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   517 ------------LGGGGLALISLLLLILDRLENQGA--EGAAELSG--SVKKQLKHLGLSSHASAKDLDRLVNSLSGAIT 580
Cdd:TIGR02169  619 vfgdtlvvedieAARRLMGKYRMVTLEGELFEKSGAmtGGSRAPRGgiLFSRSEPAELQRLRERLEGLKRELSSLQSELR 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   581 HSEELSRAKSSR------------------DEVEGLYTAGIELLNRLVDDCGLEAVDEGASAAHLEGVLEDIMLT----- 637
Cdd:TIGR02169  699 RIENRLDELSQElsdasrkigeiekeieqlEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDlhkle 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   638 -------HRYAVIQVGVQNEELTKIHTSKGIFSGQLRDNTKELNDILAELDEEDQESATAV--LAEIT-RRLEIETELE- 706
Cdd:TIGR02169  779 ealndleARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQeqRIDLKeQIKSIEKEIEn 858

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   707 ---RLASAESVVEKIREAVNaacksvgDGEPSLDNLAivyAEQLERAKKAIEARGKHDDLERQLIDKRPRAKRRNTKKRG 783
Cdd:TIGR02169  859 lngKKEELEEELEELEAALR-------DLESRLGDLK---KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928

                          730
                   ....*....|....*...
gi 663513256   784 LEDEATDLLASFKLGSDD 801
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEI 946
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
197-397 3.56e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 3.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  197 RQRI--LTARLNGLTKEIGTLNQKMKELSgrrgAREKMNGQLEELRRTRSGLALDVKRATDRINAREhkSRIDGLKEEID 274
Cdd:PRK02224  474 RERVeeLEAELEDLEEEVEEVEERLERAE----DLVEAEDRIERLEERREDLEELIAERRETIEEKR--ERAEELRERAA 547

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  275 ELP----DGPFPADSAQARLESLRKDISSLEDELGDLDEEIESLENEQSNLSLDPDAEGshssleavRVSDLFERVTEVE 350
Cdd:PRK02224  548 ELEaeaeEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAED--------EIERLREKREALA 619

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  351 HANNLRdeKESLSDL-----ELEEGF-ETRLKEAHSRH-------EEIVGKIEDLTERED 397
Cdd:PRK02224  620 ELNDER--RERLAEKrerkrELEAEFdEARIEEAREDKeraeeylEQVEEKLDELREERD 677
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 214-439 3.66e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 3.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  214 TLNQKMKELSGRRGAREKMNGQLEELRRTRSGLALDVKRATDRINAREhkSRIDGLKEEIDELpdgpfpadsaQARLESL 293
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA--RRIRALEQELAAL----------EAELAEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  294 RKDISSLEDELGDLDEEIESLENEQSNLSLDPDAE---GSHSSLEAVRVSDLFERVTE--VEHANNLRDEKESLSDLELE 368
Cdd:COG4942    89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllSPEDFLDAVRRLQYLKYLAParREQAEELRADLAELAALRAE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  369 ---------------EGFETRLKEAHSRHEEIVGKIEDLTEREDIANISLGKYEpQVLDAGLASEIDGAITRRYSQHSDP 433
Cdd:COG4942   169 leaeraeleallaelEEERAALEALKAERQKLLARLEKELAELAAELAELQQEA-EELEALIARLEAEAAAAAERTPAAG 247


                  ....*.
gi 663513256  434 LDRAKG 439
Cdd:COG4942   248 FAALKG 253
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
201-451 4.87e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 4.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  201 LTARLNGLTKEIGTLNQKMKELSGRR----GAREKMNGQLEELRRTRSGL-----ALDVKRATDRINARE---HKSRIDG 268
Cdd:PRK02224  204 LHERLNGLESELAELDEEIERYEEQReqarETRDEADEVLEEHEERREELetleaEIEDLRETIAETEREreeLAEEVRD 283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  269 LKEEIDELPDgpfPADSAQARLESLRKDISSLEDELGDLDEEIESLENEQSNLSLDPDAEGSHSSLEAVRVSDLFERVTE 348
Cdd:PRK02224  284 LRERLEELEE---ERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEE 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  349 vehannLRDEKESLsDLELEEGfETRLKEAHSRHEEIVGKIEDLTEREDIANISLGKYEPqvLDAGLASEidgaitrrys 428
Cdd:PRK02224  361 ------LREEAAEL-ESELEEA-REAVEDRREEIEELEEEIEELRERFGDAPVDLGNAED--FLEELREE---------- 420

                         250       260
                  ....*....|....*....|...
gi 663513256  429 qhsdpLDRAKGEVKRIESDLKAA 451
Cdd:PRK02224  421 -----RDELREREAELEATLRTA 438
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
229-370 8.98e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.57  E-value: 8.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  229 REKMNGQLEELRRTRSGLALDVKRATDRI-----NAREHKSRIDGLKEEIDELpdgpfpadsaQARLESLRKDISSLEDE 303
Cdd:PRK02224  316 REELEDRDEELRDRLEECRVAAQAHNEEAeslreDADDLEERAEELREEAAEL----------ESELEEAREAVEDRREE 385

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 663513256  304 LGDLDEEIESLENEQSNLSLDPDAEGSHSSLEAVRVSDLFERVTEVEhaNNLRDEKESLSDLE--LEEG 370
Cdd:PRK02224  386 IEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELE--ATLRTARERVEEAEalLEAG 452
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 171-394 1.37e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 1.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   171 ELPRELSAMQEQMDKLyNDEHKRGKQRQRILTARLNGLTKEIGTLNQKMKELSGRRGAREKmngQLEELRRTRSGLALDV 250
Cdd:TIGR02168  779 EAEAEIEELEAQIEQL-KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER---RLEDLEEQIEELSEDI 854

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   251 KRATDRIN-----AREHKSRIDGLKEEIDELPDGpfpADSAQARLESLRKDISSLEDELGDLDEEIESLENEQSNLSLDp 325
Cdd:TIGR02168  855 ESLAAEIEeleelIEELESELEALLNERASLEEA---LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR- 930

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   326 daegsHSSLEaVRVSDLFERVTE---------VEHANNLRDE----KESLSDLE-------------LEEgfetrLKEAH 379
Cdd:TIGR02168  931 -----LEGLE-VRIDNLQERLSEeysltleeaEALENKIEDDeeeaRRRLKRLEnkikelgpvnlaaIEE-----YEELK 999

                          250
                   ....*....|....*
gi 663513256   380 SRHEEIVGKIEDLTE 394
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTE 1014
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
567-910 5.30e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 5.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  567 DLDRLVNSLSGAITHSEELS-RAKSSRDEVEGLYTAgielLNRLVDDCGLEAVDEGASAAHLEGV------LEDIMLTHR 639
Cdd:PRK02224  259 EIEDLRETIAETEREREELAeEVRDLRERLEELEEE----RDDLLAEAGLDDADAEAVEARREELedrdeeLRDRLEECR 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  640 YAVIQVGVQNEELTKIHTskgifsgQLRDNTKELNDILAELDEEDQESATAVLAEITRRLEIETELE-----------RL 708
Cdd:PRK02224  335 VAAQAHNEEAESLREDAD-------DLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEelrerfgdapvDL 407

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  709 ASAESVVEKIREAVNAACKSVGDGEPSLDNL--AIVYAEQLERAKK----------------AIEARGKHDDLERQLIDK 770
Cdd:PRK02224  408 GNAEDFLEELREERDELREREAELEATLRTAreRVEEAEALLEAGKcpecgqpvegsphvetIEEDRERVEELEAELEDL 487

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  771 RPRAKRRNTKKRGLED--EATDLLASFKLGSDDemgsavgTGKHRLNLEGEMENERGQFTNLAKRWDkswnDFENEIEga 848
Cdd:PRK02224  488 EEEVEEVEERLERAEDlvEAEDRIERLEERRED-------LEELIAERRETIEEKRERAEELRERAA----ELEAEAE-- 554

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 663513256  849 dpiEDEAICTEKNRRDESLGEEIADLQGQLDSLSAELLNLDESDELTRKQADKKAILAELNE 910
Cdd:PRK02224  555 ---EKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLRE 613
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
171-395 8.16e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 42.59  E-value: 8.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  171 ELPRELSAMQEQMDKLyNDEHKRGKQRQRILTARLNGLTKEIGTLNQKMKELsgrrgaREKMNgqleELRRTRSGLALDV 250
Cdd:COG1340     5 ELSSSLEELEEKIEEL-REEIEELKEKRDELNEELKELAEKRDELNAQVKEL------REEAQ----ELREKRDELNEKV 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  251 KRATDRINarEHKSRIDGLKEEIDELpdgpfpaDSAQARLESLRKDISSLEdelgdldEEIESLENEQSNLSLDPDAEgs 330
Cdd:COG1340    74 KELKEERD--ELNEKLNELREELDEL-------RKELAELNKAGGSIDKLR-------KEIERLEWRQQTEVLSPEEE-- 135

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 663513256  331 hssleavrvSDLFERV----TEVEHANNLRDEKESLSDLeleegfETRLKEAHSRHEEIVGKIEDLTER 395
Cdd:COG1340   136 ---------KELVEKIkeleKELEKAKKALEKNEKLKEL------RAELKELRKEAEEIHKKIKELAEE 189
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
230-397 1.40e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 1.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  230 EKMNGQLEELRRTRSglalDVKRATDRINA----REHKSRIDGLKEEIDELPDG--PFPADSAQARLESLRKDISSLEDE 303
Cdd:COG4913   228 DALVEHFDDLERAHE----ALEDAREQIELlepiRELAERYAAARERLAELEYLraALRLWFAQRRLELLEAELEELRAE 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  304 LGDLDEEIESLENEQSNL--SLDpDAEGSHSSLEAVRVSDLfERvtEVEHANNLRDEKES--------LSDLEL-----E 368
Cdd:COG4913   304 LARLEAELERLEARLDALreELD-ELEAQIRGNGGDRLEQL-ER--EIERLERELEERERrrarlealLAALGLplpasA 379

                         170       180
                  ....*....|....*....|....*....
gi 663513256  369 EGFETRLKEAHSRHEEIVGKIEDLTERED 397
Cdd:COG4913   380 EEFAALRAEAAALLEALEEELEALEEALA 408
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
187-449 2.13e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 2.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  187 YNDEHKRGKQRQRILTARLNGLTKEIGTLNQKMKELsgrrgarEKMNGQLEELRRTRSGLALDVKRATDrinAREHKSRI 266
Cdd:PRK03918  305 YLDELREIEKRLSRLEEEINGIEERIKELEEKEERL-------EELKKKLKELEKRLEELEERHELYEE---AKAKKEEL 374

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  267 DGLKEEIDELPDGPFPA--DSAQARLESLRKDISSLEDELGDLDEEIESLENEQSNLS------------LDPDAEGSHS 332
Cdd:PRK03918  375 ERLKKRLTGLTPEKLEKelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgreLTEEHRKELL 454

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  333 SLEAVRVSDLFERVTEVEhaNNLRDEKESLSDLELEEGFETRLkeahSRHEEIVGKIEDLTERedianisLGKYEPQVLD 412
Cdd:PRK03918  455 EEYTAELKRIEKELKEIE--EKERKLRKELRELEKVLKKESEL----IKLKELAEQLKELEEK-------LKKYNLEELE 521

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 663513256  413 AGlaseidgaiTRRYSQHSDPLDRAKGEVKRIESDLK 449
Cdd:PRK03918  522 KK---------AEEYEKLKEKLIKLKGEIKSLKKELE 549
YbjD COG3593
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...
 2-48 2.38e-03

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];


Pssm-ID: 442812 [Multi-domain]  Cd Length: 359  Bit Score: 41.53  E-value: 2.38e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 663513256    2 MRIDTIHVDKYGGLNDLTLQLVNDFQVIKGLNEEGKTTLLAFIRGVF 48
Cdd:COG3593     1 MKLEKIKIKNFRSIKDLSIELSDDLTVLVGENNSGKSSILEALRLLL 47
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 229-396 2.41e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.84  E-value: 2.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  229 REKMNGQLEELRRtrsgLALDVKRATDRInaREHKSRIDGLKEEIDELPDGPFP--ADSAQARLESLRKDISSLEDELGD 306
Cdd:PRK05771   38 EELSNERLRKLRS----LLTKLSEALDKL--RSYLPKLNPLREEKKKVSVKSLEelIKDVEEELEKIEKEIKELEEEISE 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  307 LDEEIESLENEQS------NLSLDPDA--EGSHSSLEAVRVS-DLFER------------------------VTEVEHAN 353
Cdd:PRK05771  112 LENEIKELEQEIErlepwgNFDLDLSLllGFKYVSVFVGTVPeDKLEElklesdvenveyistdkgyvyvvvVVLKELSD 191

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 663513256  354 NLRDE--KESLSDLELEEG---------FETRLKEAHSRHEEIVGKIEDLTERE 396
Cdd:PRK05771  192 EVEEElkKLGFERLELEEEgtpselireIKEELEEIEKERESLLEELKELAKKY 245
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 219-456 2.48e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 41.76  E-value: 2.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  219 MKELSGRRGAREKMNGQLEELRRTrsglALDVKRATDRINAREHKSRIDGLKEEIDELPDGPFPADSAQARLESLRKDIS 298
Cdd:PLN03229  421 MKKREAVKTPVRELEGEVEKLKEQ----ILKAKESSSKPSELALNEMIEKLKKEIDLEYTEAVIAMGLQERLENLREEFS 496

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  299 --SLEDELGD--LDEEIESLENE-QSNLSLDPDAEGSHSSLEAVRvsdlfervtEVEHANNLRDEKESLSDLELEegFET 373
Cdd:PLN03229  497 kaNSQDQLMHpvLMEKIEKLKDEfNKRLSRAPNYLSLKYKLDMLN---------EFSRAKALSEKKSKAEKLKAE--INK 565

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  374 RLKEAHSRhEEIVGKIEDLteREDIANISLGKYEPqvLDAGLASEIdgaitrrysqhsdplDRAKGEvkrIESDLKAALK 453
Cdd:PLN03229  566 KFKEVMDR-PEIKEKMEAL--KAEVASSGASSGDE--LDDDLKEKV---------------EKMKKE---IELELAGVLK 622


                  ...
gi 663513256  454 SAG 456
Cdd:PLN03229  623 SMG 625
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 171-439 3.65e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 3.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  171 ELPRELSAMQEQMDKLyNDEHKRGKQRQRILTARLNGLTKEIGTLNQKMKELSGRRGAREKmngQLEELRRTRSGLALDV 250
Cdd:COG4942    24 EAEAELEQLQQEIAEL-EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA---ELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  251 KRATDRINAREHKSRIDGLKEEIDEL--PDGPFPADSAQARLESL----RKDISSLEDELGDLDEEIESLENEQSNLSld 324
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQPPLALLlsPEDFLDAVRRLQYLKYLaparREQAEELRADLAELAALRAELEAERAELE-- 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  325 pdaegshssleavrvSDLFERVTEVEHANNLRDEKES-LSDLELEEG-FETRLKEAHSRHEEIVGKIEDLTEREDIANIS 402
Cdd:COG4942   178 ---------------ALLAELEEERAALEALKAERQKlLARLEKELAeLAAELAELQQEAEELEALIARLEAEAAAAAER 242

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 663513256  403 LGKYEPQVLDAGLASEIDGAITRRYSQHSDPLDRAKG 439
Cdd:COG4942   243 TPAAGFAALKGKLPWPVSGRVVRRFGERDGGGGRNKG 279
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 672-970 4.23e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.20  E-value: 4.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   672 ELNDILAELDEEdQESATAVLAEITRRL-EIETELERLASAESVVEKIREAVNAACKSvgdgepsLDNLAIVYAEQLERA 750
Cdd:TIGR02168  271 ELRLEVSELEEE-IEELQKELYALANEIsRLEQQKQILRERLANLERQLEELEAQLEE-------LESKLDELAEELAEL 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   751 KKAI-EARGKHDDLERQLIDKRPRAKRRNTKKRGLEDEATDLLASFKLgsddemgsavgtgkhrlnLEGEMENERGQFTN 829
Cdd:TIGR02168  343 EEKLeELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ------------------LELQIASLNNEIER 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256   830 LAKR---WDKSWNDFENEIEGADPIEDEAICTEKNRRDESLGEEIADLQGQLDSLSAELLNLDEsdELTRKQADKKAILA 906
Cdd:TIGR02168  405 LEARlerLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE--ELEEAEQALDAAER 482

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 663513256   907 ELNEVNLRWAHLflvrfiiQRTREQYEGSHGSEVLIRASEHLERITGGRYTQILRVveDPGYQL 970
Cdd:TIGR02168  483 ELAQLQARLDSL-------ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISV--DEGYEA 537
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
171-321 4.46e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 4.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  171 ELPRELSAMQEQMDKLyndEHKRGKQRQRILTA----------RLNGLTKEIGTLNQKMKElsgRRGAREKMNGQLEELr 240
Cdd:COG4913   299 ELRAELARLEAELERL---EARLDALREELDELeaqirgnggdRLEQLEREIERLERELEE---RERRRARLEALLAAL- 371

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  241 rtrsGLALDVKRATDRINAREHKSRIDGLKEEIDELpdgpfpadsaQARLESLRKDISSLEDELGDLDEEIESLENEQSN 320
Cdd:COG4913   372 ----GLPLPASAEEFAALRAEAAALLEALEEELEAL----------EEALAEAEAALRDLRRELRELEAEIASLERRKSN 437


                  .
gi 663513256  321 L 321
Cdd:COG4913   438 I 438
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 175-328 4.47e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 4.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  175 ELSAMQEQMDKLyNDEHKRGKQRQRILTARLNGLTKEIGTLNQKMKElsgrrgAREKMNGQLEELRRTRSGLAL------ 248
Cdd:COG3883    38 ELDALQAELEEL-NEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE------RREELGERARALYRSGGSVSYldvllg 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256  249 --DVKRATDRINARE-----HKSRIDGLKEEIDELpdgpfpaDSAQARLESLRKDISSLEDELGDLDEEIESLENEQSNL 321
Cdd:COG3883   111 seSFSDFLDRLSALSkiadaDADLLEELKADKAEL-------EAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEAL 183


                  ....*..
gi 663513256  322 SLDPDAE 328
Cdd:COG3883   184 LAQLSAE 190
AAA_23 pfam13476
AAA domain;
7-115 9.90e-03

AAA domain;


Pssm-ID: 463890 [Multi-domain]  Cd Length: 190  Bit Score: 38.63  E-value: 9.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 663513256     7 IHVDKYGGLNDLTLQLVNDFQVIKGLNEEGKTTLLAFIRGVFFGF----SKVFPHLKMRSAPFFTEGERMGGRIEVMVEL 82
Cdd:pfam13476    1 LTIENFRSFRDQTIDFSKGLTLITGPNGSGKTTILDAIKLALYGKtsrlKRKSGGGFVKGDIRIGLEGKGKAYVEITFEN 80

                           90       100       110
                   ....*....|....*....|....*....|...
gi 663513256    83 EGKERRYAIIRHTGTKQDGELSIRDLESNGLIV 115
Cdd:pfam13476   81 NDGRYTYAIERSRELSKKKGKTKKKEILEILEI 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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