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Conserved domains on  [gi|659096552|ref|XP_008449156|]
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uncharacterized protein LOC103491103 [Cucumis melo]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 10621451)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
zf-C2H2_6 pfam13912
C2H2-type zinc finger;
139-163 4.21e-06

C2H2-type zinc finger;


:

Pssm-ID: 433576  Cd Length: 27  Bit Score: 42.23  E-value: 4.21e-06
                          10        20
                  ....*....|....*....|....*
gi 659096552  139 RCATCNKVFKSWKALFGHLRSHPER 163
Cdd:pfam13912   3 ECSECGKSFPSYQALGGHKKSHRKE 27
 
Name Accession Description Interval E-value
zf-C2H2_6 pfam13912
C2H2-type zinc finger;
139-163 4.21e-06

C2H2-type zinc finger;


Pssm-ID: 433576  Cd Length: 27  Bit Score: 42.23  E-value: 4.21e-06
                          10        20
                  ....*....|....*....|....*
gi 659096552  139 RCATCNKVFKSWKALFGHLRSHPER 163
Cdd:pfam13912   3 ECSECGKSFPSYQALGGHKKSHRKE 27
ZnF_C2H2 smart00355
zinc finger;
139-160 2.24e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 34.75  E-value: 2.24e-03
                           10        20
                   ....*....|....*....|..
gi 659096552   139 RCATCNKVFKSWKALFGHLRSH 160
Cdd:smart00355   2 RCPECGKVFKSKSALREHMRTH 23
 
Name Accession Description Interval E-value
zf-C2H2_6 pfam13912
C2H2-type zinc finger;
139-163 4.21e-06

C2H2-type zinc finger;


Pssm-ID: 433576  Cd Length: 27  Bit Score: 42.23  E-value: 4.21e-06
                          10        20
                  ....*....|....*....|....*
gi 659096552  139 RCATCNKVFKSWKALFGHLRSHPER 163
Cdd:pfam13912   3 ECSECGKSFPSYQALGGHKKSHRKE 27
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
139-160 1.02e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.74  E-value: 1.02e-03
                          10        20
                  ....*....|....*....|..
gi 659096552  139 RCATCNKVFKSWKALFGHLRSH 160
Cdd:pfam00096   2 KCPDCGKSFSRKSNLKRHLRTH 23
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
139-160 2.05e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 34.78  E-value: 2.05e-03
                          10        20
                  ....*....|....*....|..
gi 659096552  139 RCATCNKVFKSWKALFGHLRSH 160
Cdd:pfam12874   2 YCELCNVTFNSESQLKSHLQGK 23
ZnF_C2H2 smart00355
zinc finger;
139-160 2.24e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 34.75  E-value: 2.24e-03
                           10        20
                   ....*....|....*....|..
gi 659096552   139 RCATCNKVFKSWKALFGHLRSH 160
Cdd:smart00355   2 RCPECGKVFKSKSALREHMRTH 23
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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