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Conserved domains on  [gi|659089167|ref|XP_008445362|]
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uncharacterized protein LOC103488418 [Cucumis melo]

Protein Classification

nucleotide exchange factor GrpE( domain architecture ID 1562)

nucleotide exchange factor GrpE functions as a nucleotide exchange factor for DnaK and participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may also function as a thermosensor

CATH:  3.90.20.20|2.30.22.10
Gene Ontology:  GO:0000774|GO:0051087|GO:0006457|GO:0042803
SCOP:  4003783|4002724

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GrpE super family cl03075
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 140-298 6.99e-57

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


The actual alignment was detected with superfamily member PRK14143:

Pssm-ID: 446000 [Multi-domain]  Cd Length: 238  Bit Score: 183.78  E-value: 6.99e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 140 ELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIVPQTDKEKKIDIS 219
Cdd:PRK14143  71 QLEQELESLKQELEELNSQYMRIAADFDNFRKRTSREQEDLRLQLKCNTLSEILPVVDNFERARQQLKPEGEEAQALHRS 150

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 659089167 220 YQGIYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSKGPGRKSS 298
Cdd:PRK14143 151 YQGLYKQLVDVLKRLGVSPMRVVGQEFDPNLHEAVLREPSDEHPEDVVLEELQRGYHLGGRVLRHAMVKVSMGPGPSSP 229
 
Name Accession Description Interval E-value
PRK14143 PRK14143
heat shock protein GrpE; Provisional
 140-298 6.99e-57

heat shock protein GrpE; Provisional


Pssm-ID: 237624 [Multi-domain]  Cd Length: 238  Bit Score: 183.78  E-value: 6.99e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 140 ELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIVPQTDKEKKIDIS 219
Cdd:PRK14143  71 QLEQELESLKQELEELNSQYMRIAADFDNFRKRTSREQEDLRLQLKCNTLSEILPVVDNFERARQQLKPEGEEAQALHRS 150

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 659089167 220 YQGIYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSKGPGRKSS 298
Cdd:PRK14143 151 YQGLYKQLVDVLKRLGVSPMRVVGQEFDPNLHEAVLREPSDEHPEDVVLEELQRGYHLGGRVLRHAMVKVSMGPGPSSP 229
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 156-292 1.12e-50

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 164.56  E-value: 1.12e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 156 KEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIvPQTDKEKKIDISYQGIYKQFVETLRSWR 235
Cdd:COG0576   12 KDRLLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAA-EEDEDVKSLLEGVEMTLKQLLDVLEKHG 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 659089167 236 VSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSKG 292
Cdd:COG0576   91 VEEIEPVGEPFDPNLHEAVSQVPSPDVEPGTVVEVLQKGYRLGDRVLRPAMVVVAKG 147
GrpE cd00446
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 156-289 9.64e-43

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


Pssm-ID: 271355 [Multi-domain]  Cd Length: 136  Bit Score: 143.80  E-value: 9.64e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 156 KEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQiVPQTDKEKKIDISYQGIYKQFVETLRSWR 235
Cdd:cd00446    4 KDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEA-APKEEELKNLLEGVEMTLKQLLKVLEKHG 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 659089167 236 VSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKV 289
Cdd:cd00446   83 VEEIEPEGEKFDPNLHEAVMQVESPDKEPGTVVEVLQKGYKLHDRVLRPAMVVV 136
GrpE pfam01025
GrpE;
137-291 3.91e-39

GrpE;


Pssm-ID: 425996 [Multi-domain]  Cd Length: 165  Bit Score: 135.43  E-value: 3.91e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167  137 EKDELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQiVPQTDKEKKI 216
Cdd:pfam01025  12 EIESLEEEIEELEKKIEELKEKLLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNS-APENEDVKSL 90

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 659089167  217 DISYQGIYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:pfam01025  91 LEGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKPEGTVVEVLQKGYKLHDRVLRPAMVVVSK 165
 
Name Accession Description Interval E-value
PRK14143 PRK14143
heat shock protein GrpE; Provisional
 140-298 6.99e-57

heat shock protein GrpE; Provisional


Pssm-ID: 237624 [Multi-domain]  Cd Length: 238  Bit Score: 183.78  E-value: 6.99e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 140 ELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIVPQTDKEKKIDIS 219
Cdd:PRK14143  71 QLEQELESLKQELEELNSQYMRIAADFDNFRKRTSREQEDLRLQLKCNTLSEILPVVDNFERARQQLKPEGEEAQALHRS 150

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 659089167 220 YQGIYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSKGPGRKSS 298
Cdd:PRK14143 151 YQGLYKQLVDVLKRLGVSPMRVVGQEFDPNLHEAVLREPSDEHPEDVVLEELQRGYHLGGRVLRHAMVKVSMGPGPSSP 229
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 156-292 1.12e-50

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 164.56  E-value: 1.12e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 156 KEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIvPQTDKEKKIDISYQGIYKQFVETLRSWR 235
Cdd:COG0576   12 KDRLLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAA-EEDEDVKSLLEGVEMTLKQLLDVLEKHG 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 659089167 236 VSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSKG 292
Cdd:COG0576   91 VEEIEPVGEPFDPNLHEAVSQVPSPDVEPGTVVEVLQKGYRLGDRVLRPAMVVVAKG 147
GrpE cd00446
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 156-289 9.64e-43

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


Pssm-ID: 271355 [Multi-domain]  Cd Length: 136  Bit Score: 143.80  E-value: 9.64e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 156 KEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQiVPQTDKEKKIDISYQGIYKQFVETLRSWR 235
Cdd:cd00446    4 KDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEA-APKEEELKNLLEGVEMTLKQLLKVLEKHG 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 659089167 236 VSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKV 289
Cdd:cd00446   83 VEEIEPEGEKFDPNLHEAVMQVESPDKEPGTVVEVLQKGYKLHDRVLRPAMVVV 136
GrpE pfam01025
GrpE;
137-291 3.91e-39

GrpE;


Pssm-ID: 425996 [Multi-domain]  Cd Length: 165  Bit Score: 135.43  E-value: 3.91e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167  137 EKDELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQiVPQTDKEKKI 216
Cdd:pfam01025  12 EIESLEEEIEELEKKIEELKEKLLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNS-APENEDVKSL 90

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 659089167  217 DISYQGIYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:pfam01025  91 LEGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKPEGTVVEVLQKGYKLHDRVLRPAMVVVSK 165
PRK14140 PRK14140
heat shock protein GrpE; Provisional
 137-291 2.02e-33

heat shock protein GrpE; Provisional


Pssm-ID: 237622 [Multi-domain]  Cd Length: 191  Bit Score: 121.64  E-value: 2.02e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 137 EKDELSRKLSNILTEMtsgKEKYIRLQADFDNFRKRSEKE-QHNVKNNAQKeVIESLLPMIDHFEKArQQIVPQTDKEKK 215
Cdd:PRK14140  41 EEQAKIAELEAKLDEL---EERYLRLQADFENYKRRIQKEnEAAEKYRAQS-LASDLLPALDNFERA-LQIEADDEQTKS 115

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 659089167 216 IDISYQGIYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14140 116 LLKGVEMVHRQLLEALKKEGVEVIEAVGEQFDPNLHQAVMQDEDEDFESNEVVEELQKGYKLKDRVIRPSMVKVNQ 191
PRK14144 PRK14144
heat shock protein GrpE; Provisional
 140-291 3.75e-25

heat shock protein GrpE; Provisional


Pssm-ID: 184535 [Multi-domain]  Cd Length: 199  Bit Score: 99.80  E-value: 3.75e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 140 ELSRKLSniLTEMTSGK--EKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIVPQTDKEKKID 217
Cdd:PRK14144  49 ALEEQLT--LAEQKAHEnwEKSVRALAELENVRRRMEREVANAHKYGVEKLISALLPVVDSLEQALQLADKNSDPSMHEG 126

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 659089167 218 ISYQgiYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14144 127 LELT--MKLFLDALQKFDVEQIDPLGQTFDPQQHEAMSMQPAPGAPPNSVITVFQKGYKLSDRVIRPARVIVST 198
PRK14151 PRK14151
heat shock protein GrpE; Provisional
 139-291 1.49e-23

heat shock protein GrpE; Provisional


Pssm-ID: 172640 [Multi-domain]  Cd Length: 176  Bit Score: 94.84  E-value: 1.49e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 139 DELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIVPQTDKEKKIDI 218
Cdd:PRK14151  23 DDLTARVQELEEQLAAAKDQSLRAAADLQNVRRRAEQDVEKAHKFALEKFAGDLLPVVDSLERGLELSSADDEAIKPMRE 102

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 659089167 219 SYQGIYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14151 103 GVELTLKMFQDTLKRYQLEAVDPHGEPFNPEHHQAMAMQESADVEPNSVLKVFQKGYLLNGRLLRPAMVVVSK 175
PRK14158 PRK14158
heat shock protein GrpE; Provisional
 140-291 2.46e-21

heat shock protein GrpE; Provisional


Pssm-ID: 172646 [Multi-domain]  Cd Length: 194  Bit Score: 89.60  E-value: 2.46e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 140 ELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKArqqiVPQTDKEKKIDIs 219
Cdd:PRK14158  44 ELEEALAAKEAEAAANWDKYLRERADLENYRKRVQKEKEELLKYGNESLILEILPAVDNMERA----LDHADEESMSAI- 118

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 659089167 220 YQGI---YKQFVETLRSWRVSAV-ATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14158 119 IEGIrmtLSMLLSTLKKFGVTPVeAEKGTPFDPAYHQAMCQVESAEQEPNTVVAVFQKGYLLNERLLRPAMVSVAT 194
PRK14145 PRK14145
heat shock protein GrpE; Provisional
 137-291 5.54e-21

heat shock protein GrpE; Provisional


Pssm-ID: 184536 [Multi-domain]  Cd Length: 196  Bit Score: 88.82  E-value: 5.54e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 137 EKDELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIVPQTDKEKKI 216
Cdd:PRK14145  46 EIEELKQKLQQKEVEAQEYLDIAQRLKAEFENYRKRTEKEKSEMVEYGKEQVILELLPVMDNFERALASSGDYNSLKEGI 125

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 659089167 217 DIsyqgIYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14145 126 EL----IYRQFKKILDKFGVKEIEAEGQIFDPYKHHAVMQEEVEGKQPNEIIEVFQKGYYLKDKVIRPSLVKVAK 196
PRK14153 PRK14153
heat shock protein GrpE; Provisional
 151-293 5.71e-21

heat shock protein GrpE; Provisional


Pssm-ID: 184540 [Multi-domain]  Cd Length: 194  Bit Score: 88.36  E-value: 5.71e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 151 EMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQiVPQTDKEKKIDISYQGIYKQFVET 230
Cdd:PRK14153  48 EIESLKEQLFRLAAEFDNFRKRTAREMEENRKFVLEQVLLDLLEVTDNFERALES-ARTAEDMNSIVEGIEMVSKQFFSI 126

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 659089167 231 LRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSKGP 293
Cdd:PRK14153 127 LEKYGLERIECEGEEFDPHRHEAMMHVETSEVPDNTIVDVCKPGYALNSKVIRPAMVSVARNP 189
PRK14146 PRK14146
heat shock protein GrpE; Provisional
 86-291 1.98e-19

heat shock protein GrpE; Provisional


Pssm-ID: 172635 [Multi-domain]  Cd Length: 215  Bit Score: 84.78  E-value: 1.98e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167  86 EEDDGKAVEKDGYKFDGSSLQTLIEVYREAFLDGDQKTVSEVEARIKIIGREKD-ELSRKLSNILTEMTSGKEKYIRLQA 164
Cdd:PRK14146   3 ETSNNKTSEEAKANEKKSQSQTLEESKLENMNSEESQTITEETQEQAVEGAETEtSLQKELDNAKKEIESLKDSWARERA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 165 DFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEkaRQQIVPQTDKEKKIDIS-YQGIYKQFVETLRSWRVSAVATVG 243
Cdd:PRK14146  83 EFQNFKRRSAQEFVSIRKEAVKSLVSGFLNPIDNLE--RVGATQNQSEELKPFVEgVKMILKEFYSVLEKSNVIRFDPKG 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 659089167 244 RPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGE----RLLRPARVKVSK 291
Cdd:PRK14146 161 EPFDPMSMEALSSEEGDQYSEETVIDVYQAGYYYKEnedkFTLRPARVRIGK 212
PRK14160 PRK14160
heat shock protein GrpE; Provisional
 82-291 8.92e-19

heat shock protein GrpE; Provisional


Pssm-ID: 237629 [Multi-domain]  Cd Length: 211  Bit Score: 82.88  E-value: 8.92e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167  82 NVNNEEDDGKAVEKdgyKFDGSSLQTLIEV----YREAFLDGDQKTVSEVEARIKIIGREKDElSRKLSNiltEMTSGKE 157
Cdd:PRK14160  10 HENMEEDCCKENEN---KEEDKGKEEDLEFeeieKEEIIEDSEESNEVKIEELKDENNKLKEE-NKKLEN---ELEALKD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 158 KYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIVPQTDKEKKIDISyqgiYKQFVETLRSWRVS 237
Cdd:PRK14160  83 RLLRTVAEYDNYRKRTAKEKEGIYSDACEDVLKELLPVLDNLERAAAVEGSVEDLKKGIEMT----VKQFKTSLEKLGVE 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 659089167 238 AVATVGRpFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14160 159 EISTEGE-FDPNLHNAVMHVEDENYGENEIVEVFQKGYKRGDKVIRYSMVKVAN 211
PRK14163 PRK14163
heat shock protein GrpE; Provisional
 141-315 1.06e-18

heat shock protein GrpE; Provisional


Pssm-ID: 184546 [Multi-domain]  Cd Length: 214  Bit Score: 82.87  E-value: 1.06e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 141 LSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQ--QIVpqtdkekkidi 218
Cdd:PRK14163  45 LTAQLDQVRTALGERTADLQRLQAEYQNYRRRVERDRVTVKEIAVANLLSELLPVLDDVGRAREhgELV----------- 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 219 syqGIYKQFVETLRS----WRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK-GP 293
Cdd:PRK14163 114 ---GGFKSVAESLETtvakLGLQQFGKEGEPFDPTIHEALMHSYAPDVTETTCVAILQPGYRIGERTIRPARVAVAEpQP 190

                        170       180
                 ....*....|....*....|....*.
gi 659089167 294 GrksSRTIDGKQQPAA----AAGVDE 315
Cdd:PRK14163 191 G---AQTAKAKEAEGAddkeSGGPEE 213
PRK14149 PRK14149
heat shock protein GrpE; Provisional
 156-291 2.26e-18

heat shock protein GrpE; Provisional


Pssm-ID: 184538 [Multi-domain]  Cd Length: 191  Bit Score: 81.46  E-value: 2.26e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 156 KEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIVpQTDKEKKIDISYQGIYKQFVETLRSWR 235
Cdd:PRK14149  56 HEKYLRVHADFENVKKRLERDKSMALEYAYEKIALDLLPVIDALLGALKSAA-EVDKESALTKGLELTMEKLHEVLARHG 134

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 659089167 236 VSAVATVGRpFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14149 135 IEGIECLEE-FDPNFHNAIMQVKSEEKENGKIVQVLQQGYKYKGRVLRPAMVSIAK 189
PRK14147 PRK14147
heat shock protein GrpE; Provisional
 137-291 4.67e-18

heat shock protein GrpE; Provisional


Pssm-ID: 237625 [Multi-domain]  Cd Length: 172  Bit Score: 79.99  E-value: 4.67e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 137 EKDELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKArqqIVPQTDKEKKI 216
Cdd:PRK14147  19 ETDPLKAEVESLRSEIALVKADALRERADLENQRKRIARDVEQARKFANEKLLGELLPVFDSLDAG---LTAAGTEPSPL 95

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 659089167 217 DISYQGIYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14147  96 RDGLELTYKQLLKVAADNGLTLLDPVGQPFNPEHHQAISQGEAEGVAPGHVVQVFQKGYLLNERLLRPALVVVAK 170
PRK14150 PRK14150
heat shock protein GrpE; Provisional
 123-291 7.42e-18

heat shock protein GrpE; Provisional


Pssm-ID: 184539 [Multi-domain]  Cd Length: 193  Bit Score: 79.96  E-value: 7.42e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 123 TVSEVEARIKiigrekdELSRKLSNILTEMtsgKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKA 202
Cdd:PRK14150  35 ELDEADARIA-------ELEAQLAEAQAEE---RDSVLRARAEVENIRRRAEQDVEKAHKFALEKFANELLPVIDNLERA 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 203 RQQIVPQTDKEKKIdisYQGI---YKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGE 279
Cdd:PRK14150 105 LQAADKENEALKAL---IEGVeltLKSLLDTVAKFGVEVVGPVGEPFNPEVHQAISMQESEDHEPNTVMMVMQKGYTLNG 181

                        170
                 ....*....|..
gi 659089167 280 RLLRPARVKVSK 291
Cdd:PRK14150 182 RLLRPAMVMVSK 193
PRK14159 PRK14159
heat shock protein GrpE; Provisional
 137-291 5.59e-17

heat shock protein GrpE; Provisional


Pssm-ID: 172647 [Multi-domain]  Cd Length: 176  Bit Score: 77.42  E-value: 5.59e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 137 EKDELSrKLSNILTEMtsgKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKArQQIVPQTDKEKKI 216
Cdd:PRK14159  28 EDVEQN-KLQKDYDEL---KDKYMRANAEFENIKKRMEKEKLSAMAYANESFAKDLLDVLDALEAA-VNVECHDEISLKI 102

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 659089167 217 DISYQGIYKQFVETLRSWRVSAVATVGRpFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14159 103 KEGVQNTLDLFLKKLEKHGVALIKEEKE-FDPNLHEAMFHVDSENHQSGEVVQVLQKGYKIADRVIRPTKVSVAK 176
PRK10325 PRK10325
heat shock protein GrpE; Provisional
 126-294 2.55e-16

heat shock protein GrpE; Provisional


Pssm-ID: 182379 [Multi-domain]  Cd Length: 197  Bit Score: 75.86  E-value: 2.55e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 126 EVEARIKIIGREK-DELSRKLSNILTEMTSG----KEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFE 200
Cdd:PRK10325  24 EIEAVEPEASAEQvDPRDEKIANLEAQLAEAqtreRDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLD 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 201 KARQQivpqTDKEKKiDIS--YQGI---YKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGF 275
Cdd:PRK10325 104 RALEV----ADKANP-DMSamVEGIeltLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGY 178

                        170
                 ....*....|....*....
gi 659089167 276 LLGERLLRPARVKVSKGPG 294
Cdd:PRK10325 179 TLNGRTIRAAMVTVAKAKA 197
PRK14164 PRK14164
heat shock protein GrpE; Provisional
 149-287 2.88e-16

heat shock protein GrpE; Provisional


Pssm-ID: 237632 [Multi-domain]  Cd Length: 218  Bit Score: 76.38  E-value: 2.88e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 149 LTEMTsgkEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQqivpQTDKEKKidiSYQGIYKQFV 228
Cdd:PRK14164  86 LAERT---EDLQRVTAEYANYRRRTERERQAIIETAKAGVATDLLPILDDLDLAEQ----HGDLNEG---PLKAFSDKLT 155

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 659089167 229 ETLRSWRVSAVATVGRPFDPSLHEAVareesQEIKEG---IVIQELRRGFLLGERLLRPARV 287
Cdd:PRK14164 156 NVLAGLKVEKFGEEGDAFDPEIHEAV-----QDLSSGdekVLGTVLRKGYRMGDRVLRTAMV 212
PRK14154 PRK14154
heat shock protein GrpE; Provisional
 138-290 6.35e-16

heat shock protein GrpE; Provisional


Pssm-ID: 237626 [Multi-domain]  Cd Length: 208  Bit Score: 75.23  E-value: 6.35e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 138 KDELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIVPQTDKEKKID 217
Cdd:PRK14154  54 REKLEGQLTRMERKVDEYKTQYLRAQAEMDNLRKRIEREKADIIKFGSKQLITDLLPVADSLIHGLESPASEDPQVKSMR 133

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 659089167 218 ISYQGIYKQFVETLRSWRVSAV-ATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVS 290
Cdd:PRK14154 134 DGMSLTLDLLHNTLAKHGVQVInPNPGDPFDPALHEAMSVQAVPDAKPDTIIQVLQKGYQLNGRVLRAARVIVA 207
PRK14142 PRK14142
heat shock protein GrpE; Provisional
 146-289 4.15e-14

heat shock protein GrpE; Provisional


Pssm-ID: 237623  Cd Length: 223  Bit Score: 70.41  E-value: 4.15e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 146 SNILTEMTSGKEkyiRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQqivpQTDKEKKidiSYQGIYK 225
Cdd:PRK14142  46 EDKVAELTADLQ---RVQADFANYRKRALRDQQAAADRAKASVVSQLLGVLDDLERARK----HGDLESG---PLKSVAD 115

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 659089167 226 QFVETLRSWRVSAVATVGRPFDPSLHEAVARE-ESQEIKEGIVIQELRRGFLLGERLLRPARVKV 289
Cdd:PRK14142 116 KLDSALTGLGLVAFGAEGEDFDPVLHEAVQHEgDGGQGSKPVIGTVMRQGYQLGEQVLRHALVGV 180
PRK14162 PRK14162
heat shock protein GrpE; Provisional
 137-291 2.35e-13

heat shock protein GrpE; Provisional


Pssm-ID: 237631 [Multi-domain]  Cd Length: 194  Bit Score: 67.55  E-value: 2.35e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 137 EKDELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQqiVPQTDK-EKK 215
Cdd:PRK14162  40 PVEDLEKEIADLKAKNKDLEDKYLRSQAEIQNMQNRYAKERAQLIKYESQSLAKDVLPAMDNLERALA--VKADDEaAKQ 117

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 659089167 216 IDISYQGIYKQFVETLRSWRVSAVATVGRPFDPSLHEA---VAREESQeiKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14162 118 LKKGVQMTLDHLVKALKDHGVTEIKADGEKFDPTLHQAvqtVAAENDD--QKDHVVQVLQKGYQYKDRTLRPAMVVVAQ 194
PRK14155 PRK14155
heat shock protein GrpE; Provisional
 137-311 5.04e-13

heat shock protein GrpE; Provisional


Pssm-ID: 237627 [Multi-domain]  Cd Length: 208  Bit Score: 66.91  E-value: 5.04e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 137 EKDELSRKLSNILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQiVPQTDKEKKI 216
Cdd:PRK14155  14 EADDAAQEIEALKAEVAALKDQALRYAAEAENTKRRAEREMNDARAYAIQKFARDLLGAADNLGRATAA-SPKDSADPAV 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 217 DISYQGIYKQFVETLRSWRVSAVATV----GRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSKg 292
Cdd:PRK14155  93 KNFIIGVEMTEKELLGAFERNGLKKIdpakGDKFDPHLHQAMMEQPSTEVAAGGVLQVMQAGYELMGRLVRPAMVAVAA- 171

                        170
                 ....*....|....*....
gi 659089167 293 pgrKSSRTIDGKQQPAAAA 311
Cdd:PRK14155 172 ---KGSTGPAAPAEPAAGA 187
PRK14148 PRK14148
heat shock protein GrpE; Provisional
 109-291 8.68e-13

heat shock protein GrpE; Provisional


Pssm-ID: 172637 [Multi-domain]  Cd Length: 195  Bit Score: 65.93  E-value: 8.68e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 109 IEVYREAFLDGDQKTVSEVEARIKIigREKDELSRKLSNILTEMT-SGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKE 187
Cdd:PRK14148  14 LDIETAAQVETAQESASGALEELSV--EEQLERAKDTIKELEDSCdQFKDEALRAKAEMENIRKRAERDVSNARKFGIEK 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 188 VIESLLPMIDHFEKARQQIVpQTDKEKKIDISYQGIYKQFVETLRSWRVSAVATVGRPFDPSLHEAVAREESQEIKEGIV 267
Cdd:PRK14148  92 FAKELLPVIDSIEQALKHEV-KLEEAIAMKEGIELTAKMLVDILKKNGVEELDPKGEKFDPNLHEAMAMIPNPEFEDNTI 170

                        170       180
                 ....*....|....*....|....
gi 659089167 268 IQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14148 171 FDVFQKGYMLNGRIVRAAKVVIVK 194
PRK14139 PRK14139
heat shock protein GrpE; Provisional
 156-292 5.11e-12

heat shock protein GrpE; Provisional


Pssm-ID: 237621 [Multi-domain]  Cd Length: 185  Bit Score: 63.45  E-value: 5.11e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 156 KEKYIRLQADFDNFRKRSEKEQhnvkNNAQKEVIES----LLPMIDHFEKARQQivpQTDKEKKIDISYQGIYKQFVETL 231
Cdd:PRK14139  52 QDSFLRAKAETENVRRRAQEDV----AKAHKFAIESfaesLLPVKDSLEAALAD---ESGDLEKLREGVELTLKQLTSAF 124

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 659089167 232 RSWRVSAVATVGRPFDPSLHEAVAREESqEIKEGIVIQELRRGFLLGERLLRPARVKVSKG 292
Cdd:PRK14139 125 EKGRVVEINPVGEKFDPHQHQAISMVPA-EQEPNTVVAVLQKGYTIADRVLRPALVTVAAP 184
PRK14141 PRK14141
heat shock protein GrpE; Provisional
 156-315 4.94e-11

heat shock protein GrpE; Provisional


Pssm-ID: 172630  Cd Length: 209  Bit Score: 61.22  E-value: 4.94e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 156 KEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQIvPQTDKEKKiDISYQGIYKQFVETLRSWR 235
Cdd:PRK14141  51 KDRMLRLAAEMENLRKRTQRDVADARAYGIAGFARDMLSVSDNLRRALDAI-PAEARAAA-DAGLKALIEGVEMTERAML 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 236 -------VSAVATVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVSKGpGRKSSrtidgkqqPA 308
Cdd:PRK14141 129 nalerhgVKKLDPEGQKFDPNFHQAMFEVPNPDVPNNTVVQVVQAGYTIGERVLRPAMVGVAKG-GPKAA--------AE 199


                 ....*..
gi 659089167 309 AAAGVDE 315
Cdd:PRK14141 200 AGASTSE 206
PRK14157 PRK14157
heat shock protein GrpE; Provisional
 161-290 1.06e-10

heat shock protein GrpE; Provisional


Pssm-ID: 184543 [Multi-domain]  Cd Length: 227  Bit Score: 60.74  E-value: 1.06e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 161 RLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKARQQivpqtdkeKKIDISYQGIYKQFVETLRSWRVSAVA 240
Cdd:PRK14157 102 RERAEFINYRNRTQKEQDRFRQHGIIDVLTALLPALDDIDRIREH--------SEMDDSFKAVAAKIDKAFEKFGVEKFG 173

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 659089167 241 TVGRPFDPSLHEAVAREESQEIKEGIVIQELRRGFLLGERLLRPARVKVS 290
Cdd:PRK14157 174 EKGEDFDPTKHDAILHKPDPDAEKETVDTVVEAGYRIGDRVIRAARVVVA 223
PRK14161 PRK14161
heat shock protein GrpE; Provisional
 120-293 2.45e-09

heat shock protein GrpE; Provisional


Pssm-ID: 237630 [Multi-domain]  Cd Length: 178  Bit Score: 55.75  E-value: 2.45e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 120 DQKTVSEVEARIKIIGREKDELSRklsnILTEMTSGKEKYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHF 199
Cdd:PRK14161   7 ENNEQTINDIAEEIVETANPEITA----LKAEIEELKDKLIRTTAEIDNTRKRLEKARDEAKDYAIATFAKELLNVSDNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 200 EKARQQIVPQTDKEKKIDISyqGI-----------YKQFVETLRSwrvsavaTVGRPFDPSLHEAVAREESQEIKEGIVI 268
Cdd:PRK14161  83 SRALAHKPANSDVEVTNIIA--GVqmtkdeldkvfHKHHIEEIKP-------EIGSMFDYNLHNAISQIEHPDHAPNSII 153

                        170       180
                 ....*....|....*....|....*
gi 659089167 269 QELRRGFLLGERLLRPARVKVSKGP 293
Cdd:PRK14161 154 TLMQSGYKIRDRLLRPATVQVVKKP 178
PRK14156 PRK14156
heat shock protein GrpE; Provisional
 158-291 9.26e-06

heat shock protein GrpE; Provisional


Pssm-ID: 237628 [Multi-domain]  Cd Length: 177  Bit Score: 45.21  E-value: 9.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 659089167 158 KYIRLQADFDNFRKRSEKEQHNVKNNAQKEVIESLLPMIDHFEKArQQIVPQTDKEKKidiSYQGIYKQFVETLRSWRVS 237
Cdd:PRK14156  49 KYLRAHAEMQNIQRRANEERQQLQRYRSQDLAKAILPSLDNLERA-LAVEGLTDDVKK---GLEMVQESLIQALKEEGVE 124

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 659089167 238 AVATvgRPFDPSLHEAVAR-EESQEIKEGIVIQELRRGFLLGERLLRPARVKVSK 291
Cdd:PRK14156 125 EVAV--DSFDHNLHMAVQTlPADDEHPADSIAQVFQKGYKLHERLLRPAMVVVYN 177
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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