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Conserved domains on  [gi|655566906|ref|WP_028920620|]
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preprotein translocase subunit SecE [Pseudoxanthomonas suwonensis]

Protein Classification

preprotein translocase subunit SecE( domain architecture ID 10012582)

preprotein translocase subunit SecE is an essential subunit of the Sec protein translocation channel SecYEG and it clamps together the 2 halves of SecY; may contact the channel plug during translocation

Gene Ontology:  GO:0065002
PubMed:  15546659

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
secE PRK05740
preprotein translocase subunit SecE; Reviewed
 46-133 2.27e-23

preprotein translocase subunit SecE; Reviewed


:

Pssm-ID: 235587  Cd Length: 92  Bit Score: 86.80  E-value: 2.27e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655566906  46 LGDWAPQLRGLAVAAGLVAGAAVFLLSSKGRDLREFLSESRFELRKVVWPTRQETTRMTWVVIAVVIILSLILAGFDFFV 125
Cdd:PRK05740   4 LREQSLPVRALAVVVLIAAAGGVALLTAKGKAFFAFAKESRTEVRKVVWPTRQETLQTTLIVIAVVIVMALILWGLDSIL 83


                 ....*...
gi 655566906 126 KWAIELFL 133
Cdd:PRK05740  84 VWLISFIT 91
DUF6023 super family cl44903
Family of unknown function (DUF6023); This entry represents a member of a biosynthetic gene ...
 14-43 1.91e-03

Family of unknown function (DUF6023); This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001077) is described by MIBiG as an example of the following biosynthetic classes, polyketide and terpene. This family includes a protein from the alkyl-O-dihydrogeranyl- methoxyhydroquinones biosynthetic gene cluster from Actinoplanes missouriensis 431 and appears to be predominantly found in Actinobacteria.


The actual alignment was detected with superfamily member pfam19487:

Pssm-ID: 437319  Cd Length: 150  Bit Score: 36.29  E-value: 1.91e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 655566906   14 GGDIVKYAIAALLVLAGLfVWFWFAAPARA 43
Cdd:pfam19487   6 GRGVTLYALAALLLLAGG-VWWWRAAPRQA 34
 
Name Accession Description Interval E-value
secE PRK05740
preprotein translocase subunit SecE; Reviewed
 46-133 2.27e-23

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 235587  Cd Length: 92  Bit Score: 86.80  E-value: 2.27e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655566906  46 LGDWAPQLRGLAVAAGLVAGAAVFLLSSKGRDLREFLSESRFELRKVVWPTRQETTRMTWVVIAVVIILSLILAGFDFFV 125
Cdd:PRK05740   4 LREQSLPVRALAVVVLIAAAGGVALLTAKGKAFFAFAKESRTEVRKVVWPTRQETLQTTLIVIAVVIVMALILWGLDSIL 83


                 ....*...
gi 655566906 126 KWAIELFL 133
Cdd:PRK05740  84 VWLISFIT 91
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 72-134 5.73e-20

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 77.56  E-value: 5.73e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 655566906  72 SSKGRDLREFLSESRFELRKVVWPTRQETTRMTWVVIAVVIILSLILAGFDFFVKWAIELFLN 134
Cdd:COG0690    6 TGKGKKIVKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLILG 68
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 79-133 3.93e-15

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 64.76  E-value: 3.93e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 655566906   79 REFLSESRFELRKVVWPTRQETTRMTWVVIAVVIILSLILAGFDFFVKWAIELFL 133
Cdd:pfam00584   1 KKFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSILINLLL 55
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 78-132 2.51e-12

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 57.61  E-value: 2.51e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 655566906   78 LREFLSESRFELRKVVWPTRQETTRMTWVVIAVVIILSLILAGFDFFVKWAIELF 132
Cdd:TIGR00964   1 IFKFFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVFGKLISLI 55
DUF6023 pfam19487
Family of unknown function (DUF6023); This entry represents a member of a biosynthetic gene ...
 14-43 1.91e-03

Family of unknown function (DUF6023); This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001077) is described by MIBiG as an example of the following biosynthetic classes, polyketide and terpene. This family includes a protein from the alkyl-O-dihydrogeranyl- methoxyhydroquinones biosynthetic gene cluster from Actinoplanes missouriensis 431 and appears to be predominantly found in Actinobacteria.


Pssm-ID: 437319  Cd Length: 150  Bit Score: 36.29  E-value: 1.91e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 655566906   14 GGDIVKYAIAALLVLAGLfVWFWFAAPARA 43
Cdd:pfam19487   6 GRGVTLYALAALLLLAGG-VWWWRAAPRQA 34
 
Name Accession Description Interval E-value
secE PRK05740
preprotein translocase subunit SecE; Reviewed
 46-133 2.27e-23

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 235587  Cd Length: 92  Bit Score: 86.80  E-value: 2.27e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655566906  46 LGDWAPQLRGLAVAAGLVAGAAVFLLSSKGRDLREFLSESRFELRKVVWPTRQETTRMTWVVIAVVIILSLILAGFDFFV 125
Cdd:PRK05740   4 LREQSLPVRALAVVVLIAAAGGVALLTAKGKAFFAFAKESRTEVRKVVWPTRQETLQTTLIVIAVVIVMALILWGLDSIL 83


                 ....*...
gi 655566906 126 KWAIELFL 133
Cdd:PRK05740  84 VWLISFIT 91
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 72-134 5.73e-20

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 77.56  E-value: 5.73e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 655566906  72 SSKGRDLREFLSESRFELRKVVWPTRQETTRMTWVVIAVVIILSLILAGFDFFVKWAIELFLN 134
Cdd:COG0690    6 TGKGKKIVKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLILG 68
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 79-133 3.93e-15

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 64.76  E-value: 3.93e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 655566906   79 REFLSESRFELRKVVWPTRQETTRMTWVVIAVVIILSLILAGFDFFVKWAIELFL 133
Cdd:pfam00584   1 KKFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSILINLLL 55
secE PRK07597
preprotein translocase subunit SecE; Reviewed
 78-132 7.28e-13

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236066  Cd Length: 64  Bit Score: 59.16  E-value: 7.28e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 655566906  78 LREFLSESRFELRKVVWPTRQETTRMTWVVIAVVIILSLILAGFDFFVKWAIELF 132
Cdd:PRK07597  10 LKKFFKDVKAELKKVTWPTRKELVRSTIVVLVFVAFFALFFYLVDLLFSKLISLL 64
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 78-132 2.51e-12

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 57.61  E-value: 2.51e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 655566906   78 LREFLSESRFELRKVVWPTRQETTRMTWVVIAVVIILSLILAGFDFFVKWAIELF 132
Cdd:TIGR00964   1 IFKFFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVFGKLISLI 55
DUF6023 pfam19487
Family of unknown function (DUF6023); This entry represents a member of a biosynthetic gene ...
 14-43 1.91e-03

Family of unknown function (DUF6023); This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001077) is described by MIBiG as an example of the following biosynthetic classes, polyketide and terpene. This family includes a protein from the alkyl-O-dihydrogeranyl- methoxyhydroquinones biosynthetic gene cluster from Actinoplanes missouriensis 431 and appears to be predominantly found in Actinobacteria.


Pssm-ID: 437319  Cd Length: 150  Bit Score: 36.29  E-value: 1.91e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 655566906   14 GGDIVKYAIAALLVLAGLfVWFWFAAPARA 43
Cdd:pfam19487   6 GRGVTLYALAALLLLAGG-VWWWRAAPRQA 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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