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Conserved domains on  [gi|647806363|gb|AIC21447|]
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sugar ABC transporter ATP-binding protein [Pseudomonas chlororaphis]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11438927)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates; similar to Myxococcus xanthus O-antigen export system ATP-binding protein RfbB

CATH:  3.40.50.300
Gene Ontology:  GO:0042626|GO:0140359|GO:0016887|GO:0005524
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 1-256 1.84e-135

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 390.21  E-value: 1.84e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   1 MSSdeySIRVNGLGKCYEIYATPRDRLKQFIIPPiqrlvgcePSSYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLL 80
Cdd:COG1134    1 MSS---MIEVENVSKSYRLYHEPSRSLKELLLRR--------RRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  81 QLITGTIAPTVGTVETRGRVAALLELGSGFNPEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSS 160
Cdd:COG1134   70 KLIAGILEPTSGRVEVNGRVSALLELGAGFHPELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSS 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 161 GMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGS 240
Cdd:COG1134  150 GMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGD 229

                        250
                 ....*....|....*.
gi 647806363 241 ASQVLLDYRKLLHQEE 256
Cdd:COG1134  230 PEEVIAAYEALLAGRE 245
Wzt_C-like cd10147
C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; ...
 313-468 2.08e-20

C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; The Escherichia coli ABC protein Wzt consists of 2 domains, a conventional ABC domain that binds ATP and utilizes its energy to transport molecules across membranes, and a C terminal domain which is responsible for its target molecule specificity. Wzt is part of the ATP-binding-cassette (ABC) transporter complex, responsible for the transport of the O-antigenic polysaccharide (O-PS) portion of lipopolysaccharide (LPS), a major component of the outer membrane of Gram-negative bacteria. This CD includes Wzt proteins from two Escherichia coli serotypes O8 and O9a, WztO8 and WztO9a; these proteins are specific for their cognate polysaccharides (O8 or O9a O-PS).


:

Pssm-ID: 199902  Cd Length: 144  Bit Score: 87.42  E-value: 2.08e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 313 SFGDGGVEVLSVSTFGVDDEPCAVFYPGDVIRIRVDCVSHINTDCINVGVRIRSREGIKMYSWGTLNQDMQVLaglrege 392
Cdd:cd10147    4 RFGSGGARITDVELLDEDGEPVNTFRSGEPVTLRIEYEVNEDIEDPVVGFTIKDRDGQDVFGTNTLLLGGVLP------- 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 393 lfwkrQLTGGEQFHVWLECDCSLGSNLYEIQASISYEGkpdySAQRILHWKDEAAFFQtLMRQDEYFFGGVSDLHM 468
Cdd:cd10147   77 -----SLKAGGEGEVEFTFPLPLNPGEYSLSVALADGD----GHHEVLDWIDDALSFE-VESSSKSLFVGLVDLPH 142
 
Name Accession Description Interval E-value
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 1-256 1.84e-135

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 390.21  E-value: 1.84e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   1 MSSdeySIRVNGLGKCYEIYATPRDRLKQFIIPPiqrlvgcePSSYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLL 80
Cdd:COG1134    1 MSS---MIEVENVSKSYRLYHEPSRSLKELLLRR--------RRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  81 QLITGTIAPTVGTVETRGRVAALLELGSGFNPEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSS 160
Cdd:COG1134   70 KLIAGILEPTSGRVEVNGRVSALLELGAGFHPELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSS 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 161 GMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGS 240
Cdd:COG1134  150 GMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGD 229

                        250
                 ....*....|....*.
gi 647806363 241 ASQVLLDYRKLLHQEE 256
Cdd:COG1134  230 PEEVIAAYEALLAGRE 245
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 8-234 1.72e-105

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 312.93  E-value: 1.72e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   8 IRVNGLGKCYEIYATPRDRLKQFIIppiqrlvgCEPSSYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTI 87
Cdd:cd03220    1 IELENVSKSYPTYKGGSSSLKKLGI--------LGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIY 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  88 APTVGTVETRGRVAALLELGSGFNPEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLA 167
Cdd:cd03220   73 PPDSGTVTVRGRVSSLLGLGGGFNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLA 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 168 FAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03220  153 FAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGK 219
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 6-252 5.15e-59

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 203.20  E-value: 5.15e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   6 YSIRVNGLGKCYEIYATPRDRLKQFIIPpiqrlvgcepSSYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITG 85
Cdd:PRK13545   3 YKVKFEHVTKKYKMYNKPFDKLKDLFFR----------SKDGEYHYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAG 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  86 TIAPTVGTVETRGRvAALLELGSGFNPEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVR 165
Cdd:PRK13545  73 VTMPNKGTVDIKGS-AALIAISSGLNGQLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSR 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 166 LAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK13545 152 LGFAISVHINPDILVIDEALSVGDQTFTKKCLDKMNEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVV 231


                 ....*..
gi 647806363 246 LDYRKLL 252
Cdd:PRK13545 232 DHYDEFL 238
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 53-186 1.32e-31

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 118.52  E-value: 1.32e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE-------------TRGRVAALLElGSGFNPEFTGRDN 119
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILldgqdltdderksLRKEIGYVFQ-DPQLFPRLTVREN 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 647806363  120 VYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPV----KTYSSGMLVRLAFAVQVQIDPDILIVDEALA 186
Cdd:pfam00005  80 LRLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVgerpGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 49-253 4.95e-23

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 98.27  E-value: 4.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR--------------------------VAA 102
Cdd:TIGR04520  14 EKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLdtldeenlweirkkvgmvfqnpdnqfVGA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  103 LLELGSGFNPEftgrdNvylnamlLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVD 182
Cdd:TIGR04520  94 TVEDDVAFGLE-----N-------LGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILD 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363  183 EALAVGDALfqkrcfGR------IEKLLSD-GVTLLFVSHDQESVrTLTNRAILLKGGREVSMGSASQVLLDYRKLLH 253
Cdd:TIGR04520 162 EATSMLDPK------GRkevletIRKLNKEeGITVISITHDMEEA-VLADRVIVMNKGKIVAEGTPREIFSQVELLKE 232
Wzt_C-like cd10147
C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; ...
 313-468 2.08e-20

C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; The Escherichia coli ABC protein Wzt consists of 2 domains, a conventional ABC domain that binds ATP and utilizes its energy to transport molecules across membranes, and a C terminal domain which is responsible for its target molecule specificity. Wzt is part of the ATP-binding-cassette (ABC) transporter complex, responsible for the transport of the O-antigenic polysaccharide (O-PS) portion of lipopolysaccharide (LPS), a major component of the outer membrane of Gram-negative bacteria. This CD includes Wzt proteins from two Escherichia coli serotypes O8 and O9a, WztO8 and WztO9a; these proteins are specific for their cognate polysaccharides (O8 or O9a O-PS).


Pssm-ID: 199902  Cd Length: 144  Bit Score: 87.42  E-value: 2.08e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 313 SFGDGGVEVLSVSTFGVDDEPCAVFYPGDVIRIRVDCVSHINTDCINVGVRIRSREGIKMYSWGTLNQDMQVLaglrege 392
Cdd:cd10147    4 RFGSGGARITDVELLDEDGEPVNTFRSGEPVTLRIEYEVNEDIEDPVVGFTIKDRDGQDVFGTNTLLLGGVLP------- 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 393 lfwkrQLTGGEQFHVWLECDCSLGSNLYEIQASISYEGkpdySAQRILHWKDEAAFFQtLMRQDEYFFGGVSDLHM 468
Cdd:cd10147   77 -----SLKAGGEGEVEFTFPLPLNPGEYSLSVALADGD----GHHEVLDWIDDALSFE-VESSSKSLFVGLVDLPH 142
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
52-229 1.24e-17

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 80.74  E-value: 1.24e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE-TRGRVAALLELGSGFNPEF--TGRDNVylnAM--- 125
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRrAGGARVAYVPQRSEVPDSLplTVRDLV---AMgrw 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 126 --------LLGMTHDEVDERFDKIaafaDIGDYLDQPVKTYSSGMLVRLAFA-VQVQiDPDILIVDEALAVGDALFQKRC 196
Cdd:NF040873  84 arrglwrrLTRDDRAAVDDALERV----GLADLAGRQLGELSGGQRQRALLAqGLAQ-EADLLLLDEPTTGLDAESRERI 158

                        170       180       190
                 ....*....|....*....|....*....|...
gi 647806363 197 FGRIEKLLSDGVTLLFVSHDQESVRTLTNRAIL 229
Cdd:NF040873 159 IALLAEEHARGATVVVVTHDLELVRRADPCVLL 191
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
52-183 3.53e-15

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 78.24  E-value: 3.53e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGT------------VETRGRVaallelgsGFNP------- 112
Cdd:NF033858 281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEawlfgqpvdagdIATRRRV--------GYMSqafslyg 352

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 647806363 113 EFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE 183
Cdd:NF033858 353 ELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDE 423
Wzt_C pfam14524
Wzt C-terminal domain; This domain is found at the C-terminus of the Wzt protein. The crystal ...
 314-466 5.64e-13

Wzt C-terminal domain; This domain is found at the C-terminus of the Wzt protein. The crystal structure of C-Wzt(O9a) reveals a beta sandwich with an immunoglobulin-like topology that contains the O-antigenic polysaccharide binding pocket. This domain is often associated with the ABC-transporter domain.


Pssm-ID: 464200  Cd Length: 141  Bit Score: 66.20  E-value: 5.64e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  314 FGDGGVEVLSVSTFGVDDEPCAVFYPGDVIRIRVDCVSHINTDCINVGVRIRSREGIKMYSWGTLNQDMQVLAglregel 393
Cdd:pfam14524   3 YGSGEAEIIDVELLDEDGKPTNTFESGEEVTLRIKVRFHEDVEDPIFGFTIKDRLGQEVFGTNTFLEGKSLGA------- 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 647806363  394 fwkrqLTGGEQFHVWLECDCSLGSNLYEIQASISYEGKPDYSAQrILHWKDEAAFFQTLMRqDEYFFGGVSDL 466
Cdd:pfam14524  76 -----LKAGEVVEVEFRFKLNLQPGEYLLSVAIEDADGEQHEHV-VYDWLDDALVFEVGVS-SKNVFVGLVDL 141
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 62-229 3.28e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.46  E-value: 3.28e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363    62 KGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVetrgrvaallelgsgfnpeftgrdnVYLNAmllgmthdevdERFDKI 141
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV-------------------------IYIDG-----------EDILEE 44

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   142 AAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQK------RCFGRIEKLLSDGVTLLFVSH 215
Cdd:smart00382  45 VLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEAllllleELRLLLLLKSEKNLTVILTTN 124

                          170
                   ....*....|....
gi 647806363   216 DQESVRTLTNRAIL 229
Cdd:smart00382 125 DEKDLGPALLRRRF 138
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
49-244 5.44e-09

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 57.82  E-value: 5.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSG--KSTLLQLITGtiaPTVGTVETR------GRVAALLELGS------GFNPEF 114
Cdd:NF000106  25 EVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGRRPWRf*twcaNRRALRRTIG*hrpvr*GRRESF 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQK 194
Cdd:NF000106 102 SGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRN 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 647806363 195 RCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:NF000106 182 EVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
52-183 1.44e-06

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 50.89  E-value: 1.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVET----------RGRVA---ALLELGSGFN--PEFTG 116
Cdd:NF033858  16 ALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVlggdmadarhRRAVCpriAYMPQGLGKNlyPTLSV 95

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 117 RDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGM---------LVRlafavqvqiDPDILIVDE 183
Cdd:NF033858  96 FENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMkqklglccaLIH---------DPDLLILDE 162
GguA NF040905
sugar ABC transporter ATP-binding protein;
52-85 1.05e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 44.78  E-value: 1.05e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITG 85
Cdd:NF040905  16 ALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG 49
 
Name Accession Description Interval E-value
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 1-256 1.84e-135

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 390.21  E-value: 1.84e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   1 MSSdeySIRVNGLGKCYEIYATPRDRLKQFIIPPiqrlvgcePSSYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLL 80
Cdd:COG1134    1 MSS---MIEVENVSKSYRLYHEPSRSLKELLLRR--------RRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  81 QLITGTIAPTVGTVETRGRVAALLELGSGFNPEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSS 160
Cdd:COG1134   70 KLIAGILEPTSGRVEVNGRVSALLELGAGFHPELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSS 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 161 GMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGS 240
Cdd:COG1134  150 GMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGD 229

                        250
                 ....*....|....*.
gi 647806363 241 ASQVLLDYRKLLHQEE 256
Cdd:COG1134  230 PEEVIAAYEALLAGRE 245
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 8-234 1.72e-105

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 312.93  E-value: 1.72e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   8 IRVNGLGKCYEIYATPRDRLKQFIIppiqrlvgCEPSSYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTI 87
Cdd:cd03220    1 IELENVSKSYPTYKGGSSSLKKLGI--------LGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIY 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  88 APTVGTVETRGRVAALLELGSGFNPEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLA 167
Cdd:cd03220   73 PPDSGTVTVRGRVSSLLGLGGGFNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLA 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 168 FAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03220  153 FAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGK 219
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 6-252 5.15e-59

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 203.20  E-value: 5.15e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   6 YSIRVNGLGKCYEIYATPRDRLKQFIIPpiqrlvgcepSSYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITG 85
Cdd:PRK13545   3 YKVKFEHVTKKYKMYNKPFDKLKDLFFR----------SKDGEYHYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAG 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  86 TIAPTVGTVETRGRvAALLELGSGFNPEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVR 165
Cdd:PRK13545  73 VTMPNKGTVDIKGS-AALIAISSGLNGQLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSR 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 166 LAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK13545 152 LGFAISVHINPDILVIDEALSVGDQTFTKKCLDKMNEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVV 231


                 ....*..
gi 647806363 246 LDYRKLL 252
Cdd:PRK13545 232 DHYDEFL 238
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
7-252 3.61e-54

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 182.32  E-value: 3.61e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   7 SIRVNGLGKCYEIYATPRDRLKQFIIPPIQRlvgcepssycREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGT 86
Cdd:PRK13546   4 SVNIKNVTKEYRIYRTNKERMKDALIPKHKN----------KTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  87 IAPTVGTVETRGRVAaLLELGSGFNPEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRL 166
Cdd:PRK13546  74 LSPTVGKVDRNGEVS-VIAISAGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 167 AFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLL 246
Cdd:PRK13546 153 GFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLP 232


                 ....*.
gi 647806363 247 DYRKLL 252
Cdd:PRK13546 233 KYEAFL 238
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
52-245 4.14e-45

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 157.53  E-value: 4.14e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV------------ETRGRVAALLElGSGFNPEFTGRDN 119
Cdd:COG1131   15 ALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVrvlgedvardpaEVRRRIGYVPQ-EPALYPDLTVREN 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 VYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEAlAVG-DALFQKRCFG 198
Cdd:COG1131   94 LRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEP-TSGlDPEARRELWE 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 647806363 199 RIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:COG1131  173 LLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELK 219
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 51-245 3.68e-38

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 139.22  E-value: 3.68e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE------TRGRVAALLELG-----SGFNPEFTGRDN 119
Cdd:COG4555   15 PALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILidgedvRKEPREARRQIGvlpdeRGLYDRLTVREN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 VYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGR 199
Cdd:COG4555   95 IRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREI 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 647806363 200 IEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:COG4555  175 LRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELR 220
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 45-251 2.15e-37

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 136.69  E-value: 2.15e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  45 SYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV---AALLELGS--GF---NPE--- 113
Cdd:COG1122    9 SYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDitkKNLRELRRkvGLvfqNPDdql 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 114 F--TGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDAL 191
Cdd:COG1122   89 FapTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPR 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 192 FQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLDYRKL 251
Cdd:COG1122  169 GRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDYELL 228
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 52-234 9.83e-34

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 126.18  E-value: 9.83e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-----------ETRGRVAALLElGSGFNPEFTGRDNV 120
Cdd:cd03268   15 VLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEItfdgksyqkniEALRRIGALIE-APGFYPNLTARENL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 YLNAMLLGMTHDEVDERFDkIAAFADIGdylDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRI 200
Cdd:cd03268   94 RLLARLLGIRKKRIDEVLD-VVGLKDSA---KKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPDGIKELRELI 169

                        170       180       190
                 ....*....|....*....|....*....|....
gi 647806363 201 EKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03268  170 LSLRDQGITVLISSHLLSEIQKVADRIGIINKGK 203
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 51-234 7.83e-33

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 123.73  E-value: 7.83e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS-----GF---NPE--FTG---R 117
Cdd:cd03225   15 PALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKElrrkvGLvfqNPDdqFFGptvE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCF 197
Cdd:cd03225   95 EEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELL 174

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 647806363 198 GRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03225  175 ELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 51-234 4.30e-32

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 120.58  E-value: 4.30e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV------------ETRGRVAALLElGSGFNPEFTGRD 118
Cdd:cd03230   14 TALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIkvlgkdikkepeEVKRRIGYLPE-EPSLYENLTVRE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 NVYlnamllgmthdevderfdkiaafadigdyldqpvktYSSGMLVRLAFAVQVQIDPDILIVDEALaVG-DALFQKRCF 197
Cdd:cd03230   93 NLK------------------------------------LSGGMKQRLALAQALLHDPELLILDEPT-SGlDPESRREFW 135

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 647806363 198 GRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03230  136 ELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGR 172
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 53-186 1.32e-31

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 118.52  E-value: 1.32e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE-------------TRGRVAALLElGSGFNPEFTGRDN 119
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILldgqdltdderksLRKEIGYVFQ-DPQLFPRLTVREN 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 647806363  120 VYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPV----KTYSSGMLVRLAFAVQVQIDPDILIVDEALA 186
Cdd:pfam00005  80 LRLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVgerpGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 48-239 1.17e-30

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 117.77  E-value: 1.17e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  48 REYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-VAALLELGSGFNPEFTG-------RDN 119
Cdd:cd03269   11 GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKpLDIAARNRIGYLPEERGlypkmkvIDQ 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 -VYLnAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFG 198
Cdd:cd03269   91 lVYL-AQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKD 169

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 647806363 199 RIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMG 239
Cdd:cd03269  170 VIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 45-245 1.81e-30

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 118.27  E-value: 1.81e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  45 SYcREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR--VAALLELG-----SGFNPEF--T 115
Cdd:COG1121   15 SY-GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKppRRARRRIGyvpqrAEVDWDFpiT 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 GRDNVYLNAM----LLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGML--VRLAFA-VQvqiDPDILIVDEALAvG 188
Cdd:COG1121   94 VRDVVLMGRYgrrgLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQqrVLLARAlAQ---DPDLLLLDEPFA-G 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363 189 -DALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGReVSMGSASQVL 245
Cdd:COG1121  170 vDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRGL-VAHGPPEEVL 226
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 51-251 9.02e-30

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 121.55  E-value: 9.02e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTV---GTV------------ETRGRVAALL--ELGSGFNPE 113
Cdd:COG1123   20 PAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGrisGEVlldgrdllelseALRGRRIGMVfqDPMTQLNPV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 114 fTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQ 193
Cdd:COG1123  100 -TVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALDVTTQ 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 194 KRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLDYRKL 251
Cdd:COG1123  179 AEILDLLRELQRErGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQAL 237
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 51-224 1.32e-29

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 114.88  E-value: 1.32e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV---------AALLELG--SGFNPEFTGRDN 119
Cdd:COG4133   16 LLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPirdaredyrRRLAYLGhaDGLKPELTVREN 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 VYLNAMLLGMTHDevDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE---ALavgDALFQKRC 196
Cdd:COG4133   96 LRFWAALYGLRAD--REAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEpftAL---DAAGVALL 170

                        170       180       190
                 ....*....|....*....|....*....|.
gi 647806363 197 FGRIEKLLSDGVTLLFVSHDQ---ESVRTLT 224
Cdd:COG4133  171 AELIAAHLARGGAVLLTTHQPlelAAARVLD 201
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 52-241 1.66e-29

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 115.16  E-value: 1.66e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV------------ETRGRVAALLELGSgFNPEFTGRDN 119
Cdd:cd03265   15 AVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRAtvaghdvvreprEVRRRIGIVFQDLS-VDDELTGWEN 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 VYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGR 199
Cdd:cd03265   94 LYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEY 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 647806363 200 IEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSA 241
Cdd:cd03265  174 IEKLKEEfGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTP 216
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 52-240 7.84e-29

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 112.98  E-value: 7.84e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG------RVAALLELGS--GFN---PEFTGRDNV 120
Cdd:cd03263   17 AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGysirtdRKAARQSLGYcpQFDalfDELTVREHL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 YLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRI 200
Cdd:cd03263   97 RFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDLI 176

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 647806363 201 EKLLSdGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGS 240
Cdd:cd03263  177 LEVRK-GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGS 215
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 52-245 4.89e-28

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 111.37  E-value: 4.89e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR------VAALLELGSG--------FnPEFTGR 117
Cdd:cd03219   15 ALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEditglpPHEIARLGIGrtfqiprlF-PELTVL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVYLnAMLLGMTH-----------DEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALA 186
Cdd:cd03219   94 ENVMV-AAQARTGSglllararreeREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAA 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 187 -VGDALFQkRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:cd03219  173 gLNPEETE-ELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVR 231
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 52-239 1.11e-27

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 109.76  E-value: 1.11e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG------RVAALLELG-----SGFNPEFTGRDNV 120
Cdd:cd03266   20 AVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGfdvvkePAEARRRLGfvsdsTGLYDRLTARENL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 YLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRI 200
Cdd:cd03266  100 EYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFI 179

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 647806363 201 EKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMG 239
Cdd:cd03266  180 RQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 52-234 1.31e-27

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 107.72  E-value: 1.31e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVEtrgrvaallelgsgfnpeFTGRDnvylnamllgMTH 131
Cdd:cd00267   14 ALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEIL------------------IDGKD----------IAK 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 132 DEVDERFDKIAafadigdYLDQpvktYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLL 211
Cdd:cd00267   66 LPLEELRRRIG-------YVPQ----LSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEEGRTVI 134

                        170       180
                 ....*....|....*....|...
gi 647806363 212 FVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd00267  135 IVTHDPELAELAADRVIVLKDGK 157
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 52-233 1.33e-27

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 109.55  E-value: 1.33e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGSG-------FNPEF--TGRDNVYL 122
Cdd:cd03235   14 VLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKRIGyvpqrrsIDRDFpiSVRDVVLM 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 123 NAM----LLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFA---VQvqiDPDILIVDEALAVGDALFQKR 195
Cdd:cd03235   94 GLYghkgLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLAralVQ---DPDLLLLDEPFAGVDPKTQED 170

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 647806363 196 CFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGG 233
Cdd:cd03235  171 IYELLRELRREGMTILVVTHDLGLVLEYFDRVLLLNRT 208
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 52-250 2.23e-27

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 110.97  E-value: 2.23e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV---------ETRGRVAALLElGSGFNPEFTGRDN-VY 121
Cdd:COG4152   16 AVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVlwdgepldpEDRRRIGYLPE-ERGLYPKMKVGEQlVY 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 LnAMLLGMTHDEVDERFDK-IAAFaDIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEA------LAVG---DAL 191
Cdd:COG4152   95 L-ARLKGLSKAEAKRRADEwLERL-GLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPfsgldpVNVEllkDVI 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 192 FQKRcfgriekllSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLDYRK 250
Cdd:COG4152  173 RELA---------AKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGR 222
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 52-252 1.59e-26

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 112.30  E-value: 1.59e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR------VAALLELG-----------SGFNPEF 114
Cdd:COG1123  280 AVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKdltklsRRSLRELRrrvqmvfqdpySSLNPRM 359

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLNAMLLG-MTHDEVDERFDkiAAFADIG---DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:COG1123  360 TVGDIIAEPLRLHGlLSRAERRERVA--ELLERVGlppDLADRYPHELSGGQRQRVAIARALALEPKLLILDEPTSALDV 437

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 647806363 191 LFQKrcfgRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD----YRKLL 252
Cdd:COG1123  438 SVQA----QILNLLRDlqrelGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANpqhpYTRAL 504
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 52-239 5.71e-26

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 104.91  E-value: 5.71e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE-----------TRGRVAALLELGSGFnPEFTGRDNV 120
Cdd:cd03259   15 ALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILidgrdvtgvppERRNIGMVFQDYALF-PHLTVAENI 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 YLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRI 200
Cdd:cd03259   94 AFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLREELREEL 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 647806363 201 EKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMG 239
Cdd:cd03259  174 KELQRElGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 52-234 7.16e-26

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 105.28  E-value: 7.16e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV-----AALLEL------------GSGFNPEF 114
Cdd:cd03257   20 ALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDllklsRRLRKIrrkeiqmvfqdpMSSLNPRM 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNvyLNAMLLGMTHDEVDERFDKIAAFADIG-----DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGD 189
Cdd:cd03257  100 TIGEQ--IAEPLRIHGKLSKKEARKEAVLLLLVGvglpeEVLNRYPHELSGGQRQRVAIARALALNPKLLIADEPTSALD 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 647806363 190 ALFQKRcfgrIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03257  178 VSVQAQ----ILDLLKKlqeelGLTLLFITHDLGVVAKIADRVAVMYAGK 223
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 49-234 8.60e-26

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 104.49  E-value: 8.60e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALL---ELGS-----------GFN--P 112
Cdd:cd03255   16 KVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLsekELAAfrrrhigfvfqSFNllP 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 113 EFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE--------- 183
Cdd:cd03255   96 DLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPKIILADEptgnldset 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 647806363 184 ALAVGDALFQkrcfgrieklLSD--GVTLLFVSHDQESVRtLTNRAILLKGGR 234
Cdd:cd03255  176 GKEVMELLRE----------LNKeaGTTIVVVTHDPELAE-YADRIIELRDGK 217
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 52-246 1.01e-24

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 101.89  E-value: 1.01e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALL----------ELG---SGFN--PEFTG 116
Cdd:cd03258   20 ALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLsgkelrkarrRIGmifQHFNllSSRTV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 RDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKrc 196
Cdd:cd03258  100 FENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTQ-- 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 647806363 197 fgRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLL 246
Cdd:cd03258  178 --SILALLRDinrelGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFA 230
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 52-245 1.12e-24

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 102.72  E-value: 1.12e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR------VAALLELGS----------GFNPEFT 115
Cdd:cd03294   39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQdiaamsRKELRELRRkkismvfqsfALLPHRT 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 GRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKR 195
Cdd:cd03294  119 VLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRRE 198

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 647806363 196 CFGRIEKLLSD-GVTLLFVSHD-QESVRtLTNRAILLKGGREVSMGSASQVL 245
Cdd:cd03294  199 MQDELLRLQAElQKTIVFITHDlDEALR-LGDRIAIMKDGRLVQVGTPEEIL 249
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 51-234 2.13e-24

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 100.35  E-value: 2.13e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGeAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE------TRGRVAALLELG-----SGFNPEFTGRDN 119
Cdd:cd03264   14 RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRidgqdvLKQPQKLRRRIGylpqeFGVYPNFTVREF 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 VYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALfQKRCFGR 199
Cdd:cd03264   93 LDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLDPE-ERIRFRN 171

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 647806363 200 IEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03264  172 LLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGK 206
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 52-245 2.30e-24

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 101.42  E-value: 2.30e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGSG--------------FNPEFTGR 117
Cdd:COG1124   20 VLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFrrrvqmvfqdpyasLHPRHTVD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVYLNAMLLGMthDEVDERFDKiaAFADIG---DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQK 194
Cdd:COG1124  100 RILAEPLRIHGL--PDREERIAE--LLEQVGlppSFLDRYPHQLSGGQRQRVAIARALILEPELLLLDEPTSALDVSVQA 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 195 rcfgRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:COG1124  176 ----EILNLLKDlreerGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLL 227
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 8-234 5.65e-24

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 100.10  E-value: 5.65e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   8 IRVNGLGKCYEIYATPrdrlkQFIIPPIQRLVGCEPssycREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTI 87
Cdd:cd03267    1 IEVSNLSKSYRVYSKE-----PGLIGSLKSLFKRKY----REVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLL 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  88 APTVGTVETRGRV------AALLELGSGFNP------EFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPV 155
Cdd:cd03267   72 QPTSGEVRVAGLVpwkrrkKFLRRIGVVFGQktqlwwDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPV 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 156 KTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03267  152 RQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRErGTTVLLTSHYMKDIEALARRVLVIDKGR 231
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 52-234 6.04e-24

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 99.25  E-value: 6.04e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLE-----LGSGFN-----PEFTGRDNVY 121
Cdd:cd03301   15 ALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPpkdrdIAMVFQnyalyPHMTVYDNIA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 LNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIE 201
Cdd:cd03301   95 FGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELK 174

                        170       180       190
                 ....*....|....*....|....*....|....
gi 647806363 202 KLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03301  175 RLQQRlGTTTIYVTHDQVEAMTMADRIAVMNDGQ 208
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
53-245 6.85e-24

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 101.42  E-value: 6.85e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV------------ETRGRVAALLELgSGFNPEFTGRDNV 120
Cdd:PRK13537  23 VDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSIslcgepvpsrarHARQRVGVVPQF-DNLDPDFTVRENL 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 YLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRI 200
Cdd:PRK13537 102 LVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERL 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 647806363 201 EKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK13537 182 RSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALI 226
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 53-245 8.24e-24

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 99.77  E-value: 8.24e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-----ETRGRVaALLELGS--GF-NPE----FTGRDNV 120
Cdd:COG1119   19 LDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDvrlfgERRGGE-DVWELRKriGLvSPAlqlrFPRDETV 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 yLNAMLLGMT-----HDEVDE----RFDKIAAFADIGDYLDQPVKTYSSGMLVRlafavqVQI------DPDILIVDEAL 185
Cdd:COG1119   98 -LDVVLSGFFdsiglYREPTDeqreRARELLELLGLAHLADRPFGTLSQGEQRR------VLIaralvkDPELLILDEPT 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 647806363 186 AvG-DALFQKRCFGRIEKLLSDG-VTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:COG1119  171 A-GlDLGARELLLALLDKLAAEGaPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVL 231
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 52-232 1.56e-23

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 98.31  E-value: 1.56e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV--------------AALLelgsgfnPEFTGR 117
Cdd:cd03293   19 ALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPvtgpgpdrgyvfqqDALL-------PWLTVL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDAlfQKRcf 197
Cdd:cd03293   92 DNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDEPFSALDA--LTR-- 167

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 647806363 198 GRIEKLLSD-----GVTLLFVSHD-QESVRtLTNRAILLKG 232
Cdd:cd03293  168 EQLQEELLDiwretGKTVLLVTHDiDEAVF-LADRVVVLSA 207
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
53-289 2.62e-23

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 100.68  E-value: 2.62e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG----RVAALLELGSG-------FNPEFTGRDNVY 121
Cdd:PRK13536  57 VNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGvpvpARARLARARIGvvpqfdnLDLEFTVRENLL 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 LNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIE 201
Cdd:PRK13536 137 VFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLR 216

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 202 KLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGS---------ASQVLLDYRKLLHQeesdyFSRLMQPTADKAQ 272
Cdd:PRK13536 217 SLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRphalidehiGCQVIEIYGGDPHE-----LSSLVKPYARRIE 291

                        250       260
                 ....*....|....*....|....
gi 647806363 273 AS-------ASQPSDVKASSEGES 289
Cdd:PRK13536 292 VSgetlfcyAPDPEQVRVQLRGRA 315
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
52-244 3.87e-23

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 98.93  E-value: 3.87e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVaaLLE---------LGSGF-NP--EFTG--- 116
Cdd:PRK13635  22 ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMV--LSEetvwdvrrqVGMVFqNPdnQFVGatv 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 RDNVYLNAMLLGMTHDEVDERFDkiAAFADIG--DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALfqk 194
Cdd:PRK13635 100 QDDVAFGLENIGVPREEMVERVD--QALRQVGmeDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPR--- 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 195 rcfGRIEKL-----LSD--GVTLLFVSHDQESVRTlTNRAILLKGGREVSMGSASQV 244
Cdd:PRK13635 175 ---GRREVLetvrqLKEqkGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEI 227
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 49-253 4.95e-23

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 98.27  E-value: 4.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR--------------------------VAA 102
Cdd:TIGR04520  14 EKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLdtldeenlweirkkvgmvfqnpdnqfVGA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  103 LLELGSGFNPEftgrdNvylnamlLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVD 182
Cdd:TIGR04520  94 TVEDDVAFGLE-----N-------LGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILD 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363  183 EALAVGDALfqkrcfGR------IEKLLSD-GVTLLFVSHDQESVrTLTNRAILLKGGREVSMGSASQVLLDYRKLLH 253
Cdd:TIGR04520 162 EATSMLDPK------GRkevletIRKLNKEeGITVISITHDMEEA-VLADRVIVMNKGKIVAEGTPREIFSQVELLKE 232
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
49-237 8.51e-23

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 96.27  E-value: 8.51e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-VAALLE----------LG---SGFN--P 112
Cdd:COG1136   20 EVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQdISSLSErelarlrrrhIGfvfQFFNllP 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 113 EFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE--------- 183
Cdd:COG1136  100 ELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPKLILADEptgnldskt 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 184 ALAVGDALFQkrcfgrieklLSD--GVTLLFVSHDQEsVRTLTNRAILLKGGREVS 237
Cdd:COG1136  180 GEEVLELLRE----------LNRelGTTIVMVTHDPE-LAARADRVIRLRDGRIVS 224
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 53-245 1.25e-22

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 96.65  E-value: 1.25e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE------------TRGRVAALLELGSGFNPEFTGRDNV 120
Cdd:COG1120   17 LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLldgrdlaslsrrELARRIAYVPQEPPAPFGLTVRELV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 ------YLNamLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSG--MLVRLAFA-VQvqiDPDILIVDE---ALavg 188
Cdd:COG1120   97 algrypHLG--LFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGerQRVLIARAlAQ---EPPLLLLDEptsHL--- 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 647806363 189 DALFQKRCFGRIEKLLSD-GVTLLFVSHDqesvrtLT------NRAILLKGGREVSMGSASQVL 245
Cdd:COG1120  169 DLAHQLEVLELLRRLARErGRTVVMVLHD------LNlaaryaDRLVLLKDGRIVAQGPPEEVL 226
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 52-245 8.60e-22

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 94.34  E-value: 8.60e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR------VAALLELGSG--------FnPEFTGR 117
Cdd:COG0411   19 AVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRditglpPHRIARLGIArtfqnprlF-PELTVL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVYLnAMLLGMTH----------------DEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIV 181
Cdd:COG0411   98 ENVLV-AAHARLGRgllaallrlprarreeREARERAEELLERVGLADRADEPAGNLSYGQQRRLEIARALATEPKLLLL 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 182 DEALA-VGDALFQkRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:COG0411  177 DEPAAgLNPEETE-ELAELIRRLRDErGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEVR 241
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
47-234 1.31e-21

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 92.57  E-value: 1.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  47 CREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAallelgSGFNPEFTGRDNVYL--NA 124
Cdd:COG4619   10 VGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPL------SAMPPPEWRRQVAYVpqEP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 125 MLLGMT--------HDEVDERFDK---IAAFADIG---DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAvgdA 190
Cdd:COG4619   84 ALWGGTvrdnlpfpFQLRERKFDReraLELLERLGlppDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPTS---A 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 647806363 191 LFQKRcFGRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:COG4619  161 LDPEN-TRRVEELLREylaeeGRAVLWVSHDPEQIERVADRVLTLEAGR 208
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 52-247 2.75e-21

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 92.11  E-value: 2.75e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-VAAL-----LELGSGFNPE-------FTGRD 118
Cdd:cd03224   15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRdITGLppherARAGIGYVPEgrrifpeLTVEE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 NVYLNAMLLGmtHDEVDERFDKI-AAFADIGDYLDQPVKTYSSG---MlvrLAFAVQVQIDPDILIVDEALAvGDA-LFQ 193
Cdd:cd03224   95 NLLLGAYARR--RAKRKARLERVyELFPRLKERRKQLAGTLSGGeqqM---LAIARALMSRPKLLLLDEPSE-GLApKIV 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 647806363 194 KRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:cd03224  169 EEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLAD 222
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 52-236 4.40e-21

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 89.80  E-value: 4.40e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVaallelgsgfnpeftgrdnvylnamllgmth 131
Cdd:cd03216   15 ALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKE------------------------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 132 devderfdkiAAFADIGDYLDQPVktyssGMLVRLAFAVQ--VQI------DPDILIVDE---ALAVGDAlfqKRCFGRI 200
Cdd:cd03216   64 ----------VSFASPRDARRAGI-----AMVYQLSVGERqmVEIaralarNARLLILDEptaALTPAEV---ERLFKVI 125

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 647806363 201 EKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREV 236
Cdd:cd03216  126 RRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-233 4.44e-21

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 92.46  E-value: 4.44e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   1 MSSDEYSIRVNGLGKcyeIYATPRDRLKqfiippiqrlvgcepssycreywALENISFDIRKGEAFGIVGRNGSGKSTLL 80
Cdd:COG1116    1 MSAAAPALELRGVSK---RFPTGGGGVT-----------------------ALDDVSLTVAAGEFVALVGPSGCGKSTLL 54

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  81 QLITGTIAPTVGTVETRGRV--------------AALLelgsgfnPEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFAD 146
Cdd:COG1116   55 RLIAGLEKPTSGEVLVDGKPvtgpgpdrgvvfqePALL-------PWLTVLDNVALGLELRGVPKAERRERARELLELVG 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 147 IGDYLDQPVKTYSSGM-----LVRlAFAVqvqiDPDILIVDE---ALavgDAlfQKRcfGRIEKLLSD-----GVTLLFV 213
Cdd:COG1116  128 LAGFEDAYPHQLSGGMrqrvaIAR-ALAN----DPEVLLMDEpfgAL---DA--LTR--ERLQDELLRlwqetGKTVLFV 195

                        250       260
                 ....*....|....*....|.
gi 647806363 214 SHD-QESVRtLTNRAILLKGG 233
Cdd:COG1116  196 THDvDEAVF-LADRVVVLSAR 215
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 48-255 5.02e-21

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 96.44  E-value: 5.02e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  48 REYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-------------ETRGRVAALLElgsgfNPE- 113
Cdd:COG2274  486 DSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRIlidgidlrqidpaSLRRQIGVVLQ-----DVFl 560

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 114 FTG--RDNvylnamlLGMTHDEV-DERFDKIAAFADIGDY-------LDQPV----KTYSSGMLVRLAFA---VQvqiDP 176
Cdd:COG2274  561 FSGtiREN-------ITLGDPDAtDEEIIEAARLAGLHDFiealpmgYDTVVgeggSNLSGGQRQRLAIAralLR---NP 630

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 177 DILIVDEALAVGDALFQKRCFGRIEKLLSdGVTLLFVSHDQESVRtLTNRAILLKGGREVSMGSASQVL---LDYRKLLH 253
Cdd:COG2274  631 RILILDEATSALDAETEAIILENLRRLLK-GRTVIIIAHRLSTIR-LADRIIVLDKGRIVEDGTHEELLarkGLYAELVQ 708


                 ..
gi 647806363 254 QE 255
Cdd:COG2274  709 QQ 710
cbiO PRK13644
energy-coupling factor transporter ATPase;
52-247 6.31e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 92.36  E-value: 6.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG-------RVAALLEL-GSGF-NPE--FTGR--- 117
Cdd:PRK13644  17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGidtgdfsKLQGIRKLvGIVFqNPEtqFVGRtve 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCF 197
Cdd:PRK13644  97 EDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVL 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 647806363 198 GRIEKLLSDGVTLLFVSHDQESVRTlTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK13644 177 ERIKKLHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGEPENVLSD 225
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 52-244 9.31e-21

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 90.76  E-value: 9.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-VAALLELGSGFN---------PEFTGRDNVY 121
Cdd:cd03300   15 ALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKdITNLPPHKRPVNtvfqnyalfPHLTVFENIA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 LNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRC---FG 198
Cdd:cd03300   95 FGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKLRKDMqleLK 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 647806363 199 RIEKLLsdGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:cd03300  175 RLQKEL--GITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEI 218
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
52-244 1.04e-20

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 94.70  E-value: 1.04e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAAL------LELGSG-----FN--PEFTGRD 118
Cdd:COG1129   19 ALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFrsprdaQAAGIAiihqeLNlvPNLSVAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 NVYLNAMLlgMTHDEVDERfdKI-----AAFADIG---DyLDQPVKTYSSGM--LVRLAFAVQVqiDPDILIVDE---AL 185
Cdd:COG1129   99 NIFLGREP--RRGGLIDWR--AMrrrarELLARLGldiD-PDTPVGDLSVAQqqLVEIARALSR--DARVLILDEptaSL 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 186 AVGDAlfqKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:COG1129  172 TEREV---ERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAEL 227
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 51-252 1.11e-20

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 91.14  E-value: 1.11e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS--------------GF---NPE 113
Cdd:PRK11701  20 KGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLYAlseaerrrllrtewGFvhqHPR 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 114 FTGRDNVYLNA------MLLGMTHdevderFDKIAAFAdiGDYL-----------DQPvKTYSSGMLVRLAFAVQVQIDP 176
Cdd:PRK11701 100 DGLRMQVSAGGnigerlMAVGARH------YGDIRATA--GDWLerveidaaridDLP-TTFSGGMQQRLQIARNLVTHP 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 177 DILIVDEALAVGDALFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD----YRKL 251
Cdd:PRK11701 171 RLVFMDEPTGGLDVSVQARLLDLLRGLVRElGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESGLTDQVLDDpqhpYTQL 250


                 .
gi 647806363 252 L 252
Cdd:PRK11701 251 L 251
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 52-245 1.41e-20

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 90.44  E-value: 1.41e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-VAAL--LEL---------GSGFNPEFTGRDN 119
Cdd:cd03295   16 AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEdIREQdpVELrrkigyviqQIGLFPHMTVEEN 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 VYLNAMLLGMTHDEVDERFDKIAAFADIGD--YLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRC- 196
Cdd:cd03295   96 IALVPKLLKWPKEKIRERADELLALVGLDPaeFADRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGALDPITRDQLq 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 647806363 197 --FGRIEKLLsdGVTLLFVSHD-QESVRtLTNRAILLKGGREVSMGSASQVL 245
Cdd:cd03295  176 eeFKRLQQEL--GKTIVFVTHDiDEAFR-LADRIAIMKNGEIVQVGTPDEIL 224
Wzt_C-like cd10147
C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; ...
 313-468 2.08e-20

C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; The Escherichia coli ABC protein Wzt consists of 2 domains, a conventional ABC domain that binds ATP and utilizes its energy to transport molecules across membranes, and a C terminal domain which is responsible for its target molecule specificity. Wzt is part of the ATP-binding-cassette (ABC) transporter complex, responsible for the transport of the O-antigenic polysaccharide (O-PS) portion of lipopolysaccharide (LPS), a major component of the outer membrane of Gram-negative bacteria. This CD includes Wzt proteins from two Escherichia coli serotypes O8 and O9a, WztO8 and WztO9a; these proteins are specific for their cognate polysaccharides (O8 or O9a O-PS).


Pssm-ID: 199902  Cd Length: 144  Bit Score: 87.42  E-value: 2.08e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 313 SFGDGGVEVLSVSTFGVDDEPCAVFYPGDVIRIRVDCVSHINTDCINVGVRIRSREGIKMYSWGTLNQDMQVLaglrege 392
Cdd:cd10147    4 RFGSGGARITDVELLDEDGEPVNTFRSGEPVTLRIEYEVNEDIEDPVVGFTIKDRDGQDVFGTNTLLLGGVLP------- 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 393 lfwkrQLTGGEQFHVWLECDCSLGSNLYEIQASISYEGkpdySAQRILHWKDEAAFFQtLMRQDEYFFGGVSDLHM 468
Cdd:cd10147   77 -----SLKAGGEGEVEFTFPLPLNPGEYSLSVALADGD----GHHEVLDWIDDALSFE-VESSSKSLFVGLVDLPH 142
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 52-234 3.18e-20

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 87.63  E-value: 3.18e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS--------------GFNPEFTGR 117
Cdd:cd03229   15 VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELpplrrrigmvfqdfALFPHLTVL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVylnAMLLgmthdevderfdkiaafadigdyldqpvktySSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQkrcf 197
Cdd:cd03229   95 ENI---ALGL-------------------------------SGGQQQRVALARALAMDPDVLLLDEPTSALDPITR---- 136

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 647806363 198 GRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03229  137 REVRALLKSlqaqlGITVVLVTHDLDEAARLADRVVVLRDGK 178
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 49-247 5.34e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 89.66  E-value: 5.34e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV---AALLEL----GSGF-NP--EFTG-- 116
Cdd:PRK13632  21 ENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITiskENLKEIrkkiGIIFqNPdnQFIGat 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 -RDNVYL---NAMLlgmTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALF 192
Cdd:PRK13632 101 vEDDIAFgleNKKV---PPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKG 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 193 QKRCFGRIEKLLSDGV-TLLFVSHDQESVrTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK13632 178 KREIKKIMVDLRKTRKkTLISITHDMDEA-ILADKVIVFSEGKLIAQGKPKEILNN 232
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 8-240 5.54e-20

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 90.53  E-value: 5.54e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   8 IRVNGLGKCYEIY-------ATPRDRLKqfiippiqrlvgcepssycREY---WALENISFDIRKGEAFGIVGRNGSGKS 77
Cdd:COG4586    2 IEVENLSKTYRVYekepglkGALKGLFR-------------------REYrevEAVDDISFTIEPGEIVGFIGPNGAGKS 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  78 TLLQLITGTIAPTVGTVetrgRVAallelgsGFNP-----EFTGR------------------DNVYLNAMLLGMTHDEV 134
Cdd:COG4586   63 TTIKMLTGILVPTSGEV----RVL-------GYVPfkrrkEFARRigvvfgqrsqlwwdlpaiDSFRLLKAIYRIPDAEY 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 135 DERFDKIAAFADIGDYLDQPVKTYSSG--MLVRLAFAVqvqI-DPDILIVDEAlAVG-DALFQKrcfgRIEKLLSD---- 206
Cdd:COG4586  132 KKRLDELVELLDLGELLDTPVRQLSLGqrMRCELAAAL---LhRPKILFLDEP-TIGlDVVSKE----AIREFLKEynre 203

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 647806363 207 -GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGS 240
Cdd:COG4586  204 rGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGS 238
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 53-216 1.94e-19

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 90.89  E-value: 1.94e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV-AALLELGSGFNPEFTGRDNVY---------- 121
Cdd:COG0488   14 LDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGLrIGYLPQEPPLDDDLTVLDTVLdgdaelrale 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 --LNAMLLGMTHDEVD-ERFDKI-AAFADIGDY-------------------LDQPVKTYSSGMLVRLAFAvqvQI---D 175
Cdd:COG0488   94 aeLEELEAKLAEPDEDlERLAELqEEFEALGGWeaearaeeilsglgfpeedLDRPVSELSGGWRRRVALA---RAllsE 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 647806363 176 PDILIVDE------ALAVgdalfqkrcfGRIEKLLSD--GvTLLFVSHD 216
Cdd:COG0488  171 PDLLLLDEptnhldLESI----------EWLEEFLKNypG-TVLVVSHD 208
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 53-244 2.27e-19

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 86.79  E-value: 2.27e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR------VAALLELGSGFNPEF---------TGR 117
Cdd:cd03261   16 LKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEdisglsEAELYRLRRRMGMLFqsgalfdslTVF 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVylnAMLLGMTHDEVDERFDKIA----AFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE--------AL 185
Cdd:cd03261   96 ENV---AFPLREHTRLSEEEIREIVleklEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLYDEptagldpiAS 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 186 AVGDALFQkrcfgRIEKLLsdGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:cd03261  173 GVIDDLIR-----SLKKEL--GLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 53-236 2.31e-19

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 90.51  E-value: 2.31e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVetrgRVAALLELG------SGFNPEFT----------G 116
Cdd:COG0488  331 LDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTV----KLGETVKIGyfdqhqEELDPDKTvldelrdgapG 406

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 RDNVYLNAMLlgmthdevdERFDkiaaFAdiGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE--------ALAVg 188
Cdd:COG0488  407 GTEQEVRGYL---------GRFL----FS--GDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEptnhldieTLEA- 470

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 647806363 189 dalfqkrcfgrIEKLLSD--GvTLLFVSHDQESVRTLTNRAILLKGGREV 236
Cdd:COG0488  471 -----------LEEALDDfpG-TVLLVSHDRYFLDRVATRILEFEDGGVR 508
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 52-244 3.00e-19

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 86.62  E-value: 3.00e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALL---ELGSGFN-------PEFTGRDNVy 121
Cdd:cd03296   17 ALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVpvqERNVGFVfqhyalfRHMTVFDNV- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 lnAMLLGMTH-------DEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQK 194
Cdd:cd03296   96 --AFGLRVKPrserppeAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKVRK 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 647806363 195 RCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:cd03296  174 ELRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEV 224
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 53-234 4.10e-19

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 83.65  E-value: 4.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVaallelgsgfnpeftgrdnvylnamllgmthd 132
Cdd:cd03221   16 LKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTV-------------------------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 133 evderfdKIAafadigdYLDQpvktYSSGMLVRLAFAVQVQIDPDILIVDE------ALAVgDALfqkrcfgrIEKLLSD 206
Cdd:cd03221   64 -------KIG-------YFEQ----LSGGEKMRLALAKLLLENPNLLLLDEptnhldLESI-EAL--------EEALKEY 116

                        170       180
                 ....*....|....*....|....*...
gi 647806363 207 GVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03221  117 PGTVILVSHDRYFLDQVATKIIELEDGK 144
cbiO PRK13637
energy-coupling factor transporter ATPase;
52-251 1.00e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 86.25  E-value: 1.00e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV---------------ETRGRVAALLELgsgfnPEF-- 114
Cdd:PRK13637  22 ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIiidgvditdkkvklsDIRKKVGLVFQY-----PEYql 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 ---TGRDNVYLNAMLLGMTHDEVDERFDKIAAFA--DIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGD 189
Cdd:PRK13637  97 feeTIEKDIAFGPINLGLSEEEIENRVKRAMNIVglDYEDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLD 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 647806363 190 ALFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLDYRKL 251
Cdd:PRK13637 177 PKGRDEILNKIKELHKEyNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKEVETL 239
cbiO PRK13650
energy-coupling factor transporter ATPase;
49-244 1.31e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 85.55  E-value: 1.31e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRvaALLE---------LGSGF-NP--EFTG 116
Cdd:PRK13650  19 EKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGD--LLTEenvwdirhkIGMVFqNPdnQFVG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 ---RDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQ 193
Cdd:PRK13650  97 atvEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGR 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 647806363 194 KRCFGRIEKLLSD-GVTLLFVSHDQESVrTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK13650 177 LELIKTIKGIRDDyQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPREL 227
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 52-247 1.40e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 85.67  E-value: 1.40e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-----VAALLELGSGFNPEFTGRDN------- 119
Cdd:PRK13636  21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKpidysRKGLMKLRESVGMVFQDPDNqlfsasv 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 ---VYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRC 196
Cdd:PRK13636 101 yqdVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEI 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 647806363 197 FGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK13636 181 MKLLVEMQKElGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAE 232
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 53-245 4.20e-18

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 83.49  E-value: 4.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE------TRGRVAALLEL--------------GSgfnp 112
Cdd:COG1127   21 LDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILvdgqdiTGLSEKELYELrrrigmlfqggalfDS---- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 113 eFTGRDNV--YLNaMLLGMTHDEVDER-FDKIAAF--ADIGDY----LdqpvktySSGMLVRLAFAVQVQIDPDILIVDE 183
Cdd:COG1127   97 -LTVFENVafPLR-EHTDLSEAEIRELvLEKLELVglPGAADKmpseL-------SGGMRKRVALARALALDPEILLYDE 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 647806363 184 --------ALAVGDALFQKrcfgrieklLSD--GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:COG1127  168 ptagldpiTSAVIDELIRE---------LRDelGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELL 230
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 51-239 6.54e-18

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 81.33  E-value: 6.54e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVetrgrvaallelgsgfnpEFTGRDnvylnamLLGMT 130
Cdd:cd03214   13 TVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEI------------------LLDGKD-------LASLS 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 131 HdevDERFDKIA------AFADIGDYLDQPVKTYSSG--MLVRLAFAVqVQiDPDILIVDEALAVGDALFQKRCFGRIEK 202
Cdd:cd03214   68 P---KELARKIAyvpqalELLGLAHLADRPFNELSGGerQRVLLARAL-AQ-EPPILLLDEPTSHLDIAHQIELLELLRR 142

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 647806363 203 L-LSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMG 239
Cdd:cd03214  143 LaRERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 45-247 1.21e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 82.82  E-value: 1.21e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  45 SYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV-----AALLE----LGSGF-NPE- 113
Cdd:PRK13639  10 SYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPikydkKSLLEvrktVGIVFqNPDd 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 114 --F--TGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGD 189
Cdd:PRK13639  90 qlFapTVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLD 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 647806363 190 AlfqkRCFGRIEKLLSD----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK13639 170 P----MGASQIMKLLYDlnkeGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSD 227
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
52-229 1.24e-17

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 80.74  E-value: 1.24e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE-TRGRVAALLELGSGFNPEF--TGRDNVylnAM--- 125
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRrAGGARVAYVPQRSEVPDSLplTVRDLV---AMgrw 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 126 --------LLGMTHDEVDERFDKIaafaDIGDYLDQPVKTYSSGMLVRLAFA-VQVQiDPDILIVDEALAVGDALFQKRC 196
Cdd:NF040873  84 arrglwrrLTRDDRAAVDDALERV----GLADLAGRQLGELSGGQRQRALLAqGLAQ-EADLLLLDEPTTGLDAESRERI 158

                        170       180       190
                 ....*....|....*....|....*....|...
gi 647806363 197 FGRIEKLLSDGVTLLFVSHDQESVRTLTNRAIL 229
Cdd:NF040873 159 IALLAEEHARGATVVVVTHDLELVRRADPCVLL 191
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 52-247 1.71e-17

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 81.57  E-value: 1.71e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE------TRGRVAALLELGSGFNPE----FTG---RD 118
Cdd:COG0410   18 VLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRfdgediTGLPPHRIARLGIGYVPEgrriFPSltvEE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 NVYLNAMLLGmTHDEVDERFDKIAA-FADIGDYLDQPVKTYSSG---MlvrLAFAVQVQIDPDILIVDEA---LAvgdAL 191
Cdd:COG0410   98 NLLLGAYARR-DRAEVRADLERVYElFPRLKERRRQRAGTLSGGeqqM---LAIGRALMSRPKLLLLDEPslgLA---PL 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 192 FQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:COG0410  171 IVEEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLAD 226
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 52-236 3.24e-17

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 83.92  E-value: 3.24e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAAL------LELGSG-----FN--PEFTGRD 118
Cdd:COG3845   20 ANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIrsprdaIALGIGmvhqhFMlvPNLTVAE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 NVYL---NAMLLGMTHDEVDERfdkIAAFADigDY-----LDQPVKTYSSGMLVRlafavqVQI------DPDILIVDEA 184
Cdd:COG3845  100 NIVLglePTKGGRLDRKAARAR---IRELSE--RYgldvdPDAKVEDLSVGEQQR------VEIlkalyrGARILILDEP 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 185 LAV-----GDALFQkrcfgRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREV 236
Cdd:COG3845  169 TAVltpqeADELFE-----ILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGKVV 220
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 46-234 3.30e-17

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 80.14  E-value: 3.30e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  46 YCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVET--------RGRVAALL--ELGSGFN---- 111
Cdd:cd03292   10 YPNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVngqdvsdlRGRAIPYLrrKIGVVFQdfrl 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 112 -PEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:cd03292   90 lPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDP 169

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 647806363 191 LFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03292  170 DTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGK 213
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 52-256 3.57e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 81.32  E-value: 3.57e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-------------ETRGRVAALLElgsgfNPE---FT 115
Cdd:PRK13647  20 ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVkvmgrevnaenekWVRSKVGLVFQ-----DPDdqvFS 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 GR--DNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQ 193
Cdd:PRK13647  95 STvwDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQ 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 647806363 194 KRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASqvLLDYRKLLHQEE 256
Cdd:PRK13647 175 ETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKS--LLTDEDIVEQAG 235
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 45-246 4.13e-17

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 80.35  E-value: 4.13e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  45 SYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-------------ETRGRVAALLE---LGS 108
Cdd:cd03254   11 SYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQIlidgidirdisrkSLRSMIGVVLQdtfLFS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 109 GfnpefTGRDNVYLNAMLlgmTHDEVDERFDKIAAFADIGDYLDQPVKTY--------SSGMLVRLAFAVQVQIDPDILI 180
Cdd:cd03254   91 G-----TIMENIRLGRPN---ATDEEVIEAAKEAGAHDFIMKLPNGYDTVlgenggnlSQGERQLLAIARAMLRDPKILI 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 181 VDEALAVGDALFQKRCFGRIEKLLsDGVTLLFVSHDQESVRTlTNRAILLKGGREVSMGSASQVLL 246
Cdd:cd03254  163 LDEATSNIDTETEKLIQEALEKLM-KGRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEGTHDELLA 226
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 52-234 5.77e-17

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 82.04  E-value: 5.77e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLElgsgfnPE-------F---------T 115
Cdd:COG3839   18 ALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLP------PKdrniamvFqsyalyphmT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 GRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSG---------MLVRlafavqvqiDPDILIVDEALA 186
Cdd:COG3839   92 VYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGqrqrvalgrALVR---------EPKVFLLDEPLS 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 647806363 187 VGDALF--QKRcfGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:COG3839  163 NLDAKLrvEMR--AEIKRLHRRlGTTTIYVTHDQVEAMTLADRIAVMNDGR 211
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 52-245 6.07e-17

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 79.84  E-value: 6.07e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS-----GF----NPEFTG--RDNV 120
Cdd:cd03252   17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWlrrqvGVvlqeNVLFNRsiRDNI 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 YLNAMllGMTHDEVDErfdkIAAFADIGDYLDQPVKTY-----------SSGMLVRLAFAVQVQIDPDILIVDEALAVGD 189
Cdd:cd03252   97 ALADP--GMSMERVIE----AAKLAGAHDFISELPEGYdtivgeqgaglSGGQRQRIAIARALIHNPRILIFDEATSALD 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 190 ALfQKRCFGRIEKLLSDGVTLLFVSHDQESVRTlTNRAILLKGGREVSMGSASQVL 245
Cdd:cd03252  171 YE-SEHAIMRNMHDICAGRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELL 224
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 52-239 1.29e-16

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 78.79  E-value: 1.29e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLEL-----GSGFNPE----FTG--RDNV 120
Cdd:cd03245   19 ALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPadlrrNIGYVPQdvtlFYGtlRDNI 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 ylnamLLGMTHDEvDERFDKIAAFADIGDYLDQPVKTY-----------SSGMLVRLAFAVQVQIDPDILIVDEALAVGD 189
Cdd:cd03245   99 -----TLGAPLAD-DERILRAAELAGVTDFVNKHPNGLdlqigergrglSGGQRQAVALARALLNDPPILLLDEPTSAMD 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 647806363 190 ALFQKRCFGRIEKLLSDgVTLLFVSHDQeSVRTLTNRAILLKGGREVSMG 239
Cdd:cd03245  173 MNSEERLKERLRQLLGD-KTLIIITHRP-SLLDLVDRIIVMDSGRIVADG 220
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 55-239 1.41e-16

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 78.49  E-value: 1.41e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  55 NISFDIrKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV-----------------------AALLelgsgfn 111
Cdd:cd03297   16 KIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVlfdsrkkinlppqqrkiglvfqqYALF------- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 112 PEFTGRDNVylnamLLGMTHDEVDE---RFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVG 188
Cdd:cd03297   88 PHLNVRENL-----AFGLKRKRNREdriSVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSAL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 647806363 189 DALFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMG 239
Cdd:cd03297  163 DRALRLQLLPELKQIKKNlNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 52-244 1.61e-16

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 78.76  E-value: 1.61e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE----------------TRGRVAALLElgsGFN--PE 113
Cdd:cd03256   16 ALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLidgtdinklkgkalrqLRRQIGMIFQ---QFNliER 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 114 FTGRDNV---YLNAM-----LLGMTHDEvderfDKIAAFA-----DIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILI 180
Cdd:cd03256   93 LSVLENVlsgRLGRRstwrsLFGLFPKE-----EKQRALAalervGLLDKAYQRADQLSGGQQQRVAIARALMQQPKLIL 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 647806363 181 VDEALAVGDALFQKRCFGRIEKL-LSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:cd03256  168 ADEPVASLDPASSRQVMDLLKRInREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 49-267 2.17e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 79.74  E-value: 2.17e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE--------------------------------- 95
Cdd:PRK13651  19 ELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEwifkdeknkkktkekekvleklviqktrfkkik 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  96 ----TRGRVAALLELGSGFNPEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIG-DYLDQPVKTYSSGMLVRLAFAV 170
Cdd:PRK13651  99 kikeIRRRVGVVFQFAEYQLFEQTIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLDeSYLQRSPFELSGGQKRRVALAG 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 171 QVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLDYRK 250
Cdd:PRK13651 179 ILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIFFKDGKIIKDGDTYDILSDNKF 258

                        250
                 ....*....|....*..
gi 647806363 251 LLHQEesdyfsrlMQPT 267
Cdd:PRK13651 259 LIENN--------MEPP 267
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
36-251 2.79e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 78.98  E-value: 2.79e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  36 QRLVGCEPSSYC-------REYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-------------- 94
Cdd:PRK13633   2 NEMIKCKNVSYKyesneesTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVyvdgldtsdeenlw 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  95 ETRGR------------VAALLELGSGFNPEftgrdNvylnamlLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGM 162
Cdd:PRK13633  82 DIRNKagmvfqnpdnqiVATIVEEDVAFGPE-----N-------LGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQ 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 163 LVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLS-DGVTLLFVSHDQESVrTLTNRAILLKGGREVSMGSA 241
Cdd:PRK13633 150 KQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKkYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGTP 228

                        250
                 ....*....|
gi 647806363 242 SQVLLDYRKL 251
Cdd:PRK13633 229 KEIFKEVEMM 238
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 48-234 5.14e-16

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 75.50  E-value: 5.14e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  48 REYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGSgfnpeftGRDNVYL---NA 124
Cdd:cd03228   13 RPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLES-------LRKNIAYvpqDP 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 125 MLLGMThdevderfdkiaafadIGDYLdqpvktYSSGMLVRLAFA---VQvqiDPDILIVDEALAVGDALFQKRCFGRIE 201
Cdd:cd03228   86 FLFSGT----------------IRENI------LSGGQRQRIAIAralLR---DPPILILDEATSALDPETEALILEALR 140

                        170       180       190
                 ....*....|....*....|....*....|...
gi 647806363 202 KlLSDGVTLLFVSHDQESVRtLTNRAILLKGGR 234
Cdd:cd03228  141 A-LAKGKTVIVIAHRLSTIR-DADRIIVLDDGR 171
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 52-252 5.56e-16

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 80.11  E-value: 5.56e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTL----LQLItgtiaPTVGTVETRGR------VAALLEL------------GSg 109
Cdd:COG4172  301 AVDGVSLTLRRGETLGLVGESGSGKSTLglalLRLI-----PSEGEIRFDGQdldglsRRALRPLrrrmqvvfqdpfGS- 374

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 110 FNPEFTGRDNVY--LNAMLLGMTHDEVDERFdkIAAFADIG---DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE- 183
Cdd:COG4172  375 LSPRMTVGQIIAegLRVHGPGLSAAERRARV--AEALEEVGldpAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEp 452

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 184 --ALavgDALFQKrcfgRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLL----DY-RKL 251
Cdd:COG4172  453 tsAL---DVSVQA----QILDLLRDlqrehGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDapqhPYtRAL 525


                 .
gi 647806363 252 L 252
Cdd:COG4172  526 L 526
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 53-332 1.10e-15

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 78.73  E-value: 1.10e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV------------ETRGRVAALLELGSGFNPEFTGRDNV 120
Cdd:PRK09536  19 LDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVlvagddvealsaRAASRRVASVPQDTSLSFEFDVRQVV 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 YlnamlLGMT--------HDEVDER-FDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDAL 191
Cdd:PRK09536  99 E-----MGRTphrsrfdtWTETDRAaVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDIN 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 192 FQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL--------LDYRKLLhQEESDYFSRL 263
Cdd:PRK09536 174 HQVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLtadtlraaFDARTAV-GTDPATGAPT 252

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 647806363 264 MQPTADKAQASASQPSDVKASSEGESATPS-----NESSEKSQTPAVSGRADQMSFGDGGVEVLSVSTF-GVDDE 332
Cdd:PRK09536 253 VTPLPDPDRTEAAADTRVHVVGGGQPAARAvsrlvAAGASVSVGPVPEGDTAAETAARVGCEAVTVPPFkPIEDS 327
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 52-232 1.36e-15

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 80.06  E-value: 1.36e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363    52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVG--TVETRGRVAALLEL--GSGFNPEF-------TGRDNV 120
Cdd:TIGR01257 1954 AVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGdaTVAGKSILTNISDVhqNMGYCPQFdaiddllTGREHL 2033

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   121 YLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRI 200
Cdd:TIGR01257 2034 YLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTI 2113

                          170       180       190
                   ....*....|....*....|....*....|...
gi 647806363   201 EKLLSDGVTLLFVSHDQESVRTLTNR-AILLKG 232
Cdd:TIGR01257 2114 VSIIREGRAVVLTSHSMEECEALCTRlAIMVKG 2146
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 53-245 1.37e-15

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 76.35  E-value: 1.37e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRvaallELGSgFNPE------------------F 114
Cdd:PRK13548  18 LDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGR-----PLAD-WSPAelarrravlpqhsslsfpF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFA-VQVQI-----DPDILIVDE---AL 185
Cdd:PRK13548  92 TVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLArVLAQLwepdgPPRWLLLDEptsAL 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 186 avgDALFQKRCFgRIEKLL--SDGVTLLFVSHDqesvrtLtN-------RAILLKGGREVSMGSASQVL 245
Cdd:PRK13548 172 ---DLAHQHHVL-RLARQLahERGLAVIVVLHD------L-NlaaryadRIVLLHQGRLVADGTPAEVL 229
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
45-234 1.48e-15

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 75.47  E-value: 1.48e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  45 SYCREYWALENISFDIRKGE-AFgIVGRNGSGKSTLLQLITGTIAPTVGTVE---------TRGRVAAL-LELGSGFN-- 111
Cdd:COG2884   10 RYPGGREALSDVSLEIEKGEfVF-LTGPSGAGKSTLLKLLYGEERPTSGQVLvngqdlsrlKRREIPYLrRRIGVVFQdf 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 112 ---PEFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSG--MLVRLAFAVqvqI-DPDILIVDE-- 183
Cdd:COG2884   89 rllPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGeqQRVAIARAL---VnRPELLLADEpt 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 184 -----ALAVgdalfqkrcfgRIEKLLSD----GVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:COG2884  166 gnldpETSW-----------EIMELLEEinrrGTTVLIATHDLELVDRMPKRVLELEDGR 214
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 52-234 1.86e-15

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 74.81  E-value: 1.86e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVA-----ALLELGsgfnpefTGRDNVylnamL 126
Cdd:cd03250   20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGSIAyvsqePWIQNG-------TIRENI-----L 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 127 LGMTHDEvdERFDK----------IAAFAD-----IGDyldqpvK--TYSSGMLVRLAFAVQVQIDPDILIVDEALA--- 186
Cdd:cd03250   88 FGKPFDE--ERYEKvikacalepdLEILPDgdlteIGE------KgiNLSGGQKQRISLARAVYSDADIYLLDDPLSavd 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 647806363 187 --VGDALFQKrCFGrieKLLSDGVTLLFVSHdQESVRTLTNRAILLKGGR 234
Cdd:cd03250  160 ahVGRHIFEN-CIL---GLLLNNKTRILVTH-QLQLLPHADQIVVLDNGR 204
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
52-245 2.12e-15

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 77.77  E-value: 2.12e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV----------------ETRGRVAALLELGSGFNPEFT 115
Cdd:PRK10070  43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVlidgvdiakisdaelrEVRRKKIAMVFQSFALMPHMT 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 GRDNVYLNAMLLGMTHDEVDERfdKIAAFADIG--DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQ 193
Cdd:PRK10070 123 VLDNTAFGMELAGINAEERREK--ALDALRQVGleNYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIR 200

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 647806363 194 KRCFGRIEKLLSDGV-TLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK10070 201 TEMQDELVKLQAKHQrTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIL 253
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 52-245 2.77e-15

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 77.92  E-value: 2.77e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVET----------------RGRVA-------------- 101
Cdd:TIGR03269 299 AVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrvgdewvdmtkpgpdgRGRAKryigilhqeydlyp 378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  102 --ALLE-----LGSGFNPEFTGRDNVYLNAMlLGMTHDEVDERFDKiaafadigdYLDQpvktYSSGMLVRLAFAvQVQI 174
Cdd:TIGR03269 379 hrTVLDnlteaIGLELPDELARMKAVITLKM-VGFDEEKAEEILDK---------YPDE----LSEGERHRVALA-QVLI 443

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 647806363  175 -DPDILIVDEALAVGDALFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:TIGR03269 444 kEPRIVILDEPTGTMDPITKVDVTHSILKAREEmEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIV 516
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
52-183 3.53e-15

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 78.24  E-value: 3.53e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGT------------VETRGRVaallelgsGFNP------- 112
Cdd:NF033858 281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEawlfgqpvdagdIATRRRV--------GYMSqafslyg 352

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 647806363 113 EFTGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE 183
Cdd:NF033858 353 ELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDE 423
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 52-245 4.38e-15

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 75.86  E-value: 4.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTV---GTVETRGRvaALLELG--------------------S 108
Cdd:COG0444   20 AVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPGitsGEILFDGE--DLLKLSekelrkirgreiqmifqdpmT 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 109 GFNPEFTGRDNVYLNAML-LGMTHDEVDERFdkIAAFADIGdyLDQPVKTYSS-------GMLVRLAFAVQVQIDPDILI 180
Cdd:COG0444   98 SLNPVMTVGDQIAEPLRIhGGLSKAEARERA--IELLERVG--LPDPERRLDRyphelsgGMRQRVMIARALALEPKLLI 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 647806363 181 VDE---ALavgDALFQKrcfgRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:COG0444  174 ADEpttAL---DVTIQA----QILNLLKDlqrelGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
53-236 5.20e-15

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 75.11  E-value: 5.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-VAALLELG----------------SGFNPEFT 115
Cdd:PRK10419  28 LNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEpLAKLNRAQrkafrrdiqmvfqdsiSAVNPRKT 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 GRDNVYlNAM--LLGMTHDEVDERFDKIAAFADIGD-YLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALF 192
Cdd:PRK10419 108 VREIIR-EPLrhLLSLDKAERLARASEMLRAVDLDDsVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVL 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 647806363 193 QKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREV 236
Cdd:PRK10419 187 QAGVIRLLKKLQQQfGTACLFITHDLRLVERFCQRVMVMDNGQIV 231
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
52-247 5.57e-15

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 75.88  E-value: 5.57e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVaaLLELGS---------------GFN--PEF 114
Cdd:COG1135   20 ALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVD--LTALSErelraarrkigmifqHFNllSSR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQpvktY----SSGMLVRlafavqVQI------DPDILIVDEA 184
Cdd:COG1135   98 TVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADA----YpsqlSGGQKQR------VGIaralanNPKVLLCDEA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 185 ------------LAvgdalfqkrcfgriekLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:COG1135  168 tsaldpettrsiLD----------------LLKDinrelGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFAN 231
cbiO PRK13646
energy-coupling factor transporter ATPase;
49-252 8.67e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 74.43  E-value: 8.67e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE-----------------TRGRVAALLELgsgfn 111
Cdd:PRK13646  19 EHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTvdditithktkdkyirpVRKRIGMVFQF----- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 112 PE---FtgRDNVYLNAML----LGMTHDEVDER-FDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE 183
Cdd:PRK13646  94 PEsqlF--EDTVEREIIFgpknFKMNLDEVKNYaHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDE 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 184 ALAVGDALFQKRCFGRIEKL-LSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLDYRKLL 252
Cdd:PRK13646 172 PTAGLDPQSKRQVMRLLKSLqTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKKKLA 241
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 52-244 2.09e-14

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 72.21  E-value: 2.09e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTI-----APTVGTVETRGR--------VAAL-LELGSGF---NPeF 114
Cdd:cd03260   15 ALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNdlipgAPDEGEVLLDGKdiydldvdVLELrRRVGMVFqkpNP-F 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TG--RDNVYLNAMLLGM-THDEVDERFDKIAAFADIGDYLDQPVKTY--SSGMLVRLAFAVQVQIDPDILIVDEALAVGD 189
Cdd:cd03260   94 PGsiYDNVAYGLRLHGIkLKEELDERVEEALRKAALWDEVKDRLHALglSGGQQQRLCLARALANEPEVLLLDEPTSALD 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363 190 AlfqkRCFGRIEKL---LSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:cd03260  174 P----ISTAKIEELiaeLKKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
52-244 4.86e-14

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 73.33  E-value: 4.86e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG----------RVAALLELGSGFNPEFTGRDNVY 121
Cdd:PRK11607  34 AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGvdlshvppyqRPINMMFQSYALFPHMTVEQNIA 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 LNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIE 201
Cdd:PRK11607 114 FGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVV 193

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 647806363 202 KLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK11607 194 DILERvGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEI 237
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
52-236 5.14e-14

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 74.18  E-value: 5.14e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR------VAALLELGSG-------FNPEFTGRD 118
Cdd:PRK11288  19 ALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQemrfasTTAALAAGVAiiyqelhLVPEMTVAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 NVYLNAM--LLGMThDEVDERFDKIAAFADIGDYLD--QPVKTYSSG--MLVRLAFAVQVqiDPDILIVDEALAVGDALF 192
Cdd:PRK11288  99 NLYLGQLphKGGIV-NRRLLNYEAREQLEHLGVDIDpdTPLKYLSIGqrQMVEIAKALAR--NARVIAFDEPTSSLSARE 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 647806363 193 QKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREV 236
Cdd:PRK11288 176 IEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITVFKDGRYV 219
cbiO PRK13643
energy-coupling factor transporter ATPase;
52-268 6.14e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 72.07  E-value: 6.14e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE-----------------TRGRVAALLELGSGFNPEF 114
Cdd:PRK13643  21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTvgdivvsstskqkeikpVRKKVGVVFQFPESQLFEE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLNAMLLGMTHDEVDE-RFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQ 193
Cdd:PRK13643 101 TVLKDVAFGPQNFGIPKEKAEKiAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKAR 180

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 194 KRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL--LDYRKL--LHQEESDYFSRLMQPTA 268
Cdd:PRK13643 181 IEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFqeVDFLKAheLGVPKATHFADQLQKTG 259
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 49-216 6.33e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 71.71  E-value: 6.33e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-------------ETRGRVAALLElgsgfNPE-- 113
Cdd:PRK13648  21 ASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIfynnqaitddnfeKLRKHIGIVFQ-----NPDnq 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 114 FTGRDNVYLNAMLL---GMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:PRK13648  96 FVGSIVKYDVAFGLenhAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDP 175

                        170       180
                 ....*....|....*....|....*..
gi 647806363 191 LFQKRCFGRIEKLLSD-GVTLLFVSHD 216
Cdd:PRK13648 176 DARQNLLDLVRKVKSEhNITIISITHD 202
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 51-254 6.81e-14

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 73.65  E-value: 6.81e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-------------ETRGRVAALLElgsgfNPE-FTG 116
Cdd:COG4987  349 PVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSItlggvdlrdldedDLRRRIAVVPQ-----RPHlFDT 423

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 --RDNVYL---NAmllgmTHDEVderfdkIAAF--ADIGDYLDQPVKTY-----------SSGMLVRLAFA---VQvqiD 175
Cdd:COG4987  424 tlRENLRLarpDA-----TDEEL------WAALerVGLGDWLAALPDGLdtwlgeggrrlSGGERRRLALAralLR---D 489

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 176 PDILIVDEALAVGDALFQKRCFGRIEKLLSDGvTLLFVSHDQESVRtLTNRAILLKGGREVSMGSASQVLLD---YRKLL 252
Cdd:COG4987  490 APILLLDEPTEGLDAATEQALLADLLEALAGR-TVLLITHRLAGLE-RMDRILVLEDGRIVEQGTHEELLAQngrYRQLY 567


                 ..
gi 647806363 253 HQ 254
Cdd:COG4987  568 QR 569
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 52-192 7.89e-14

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 70.08  E-value: 7.89e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAA---------LLELG--SGFNPEFTGRDNV 120
Cdd:TIGR01189  15 LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAeqrdephenILYLGhlPGLKPELSALENL 94

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363  121 YLNAMLLGMTHDEVDErfdkiaAFADIG--DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAV----GDALF 192
Cdd:TIGR01189  95 HFWAAIHGGAQRTIED------ALAAVGltGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTAldkaGVALL 166
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 52-244 9.35e-14

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 72.44  E-value: 9.35e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVA-----------------ALlelgsgFnPEF 114
Cdd:COG3842   20 ALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVtglppekrnvgmvfqdyAL------F-PHL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNV--YLNAMllGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFA---VqvqIDPDILIVDEALAvgd 189
Cdd:COG3842   93 TVAENVafGLRMR--GVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALAralA---PEPRVLLLDEPLS--- 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 647806363 190 ALFQKRcfgRIE------KLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:COG3842  165 ALDAKL---REEmreelrRLQRElGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEI 223
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 52-234 1.44e-13

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 69.48  E-value: 1.44e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV-----AALLELGSG-------FN--PEFTGR 117
Cdd:cd03262   15 VLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKltddkKNINELRQKvgmvfqqFNlfPHLTVL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVYLNAM-LLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE---AL---AVGDA 190
Cdd:cd03262   95 ENITLAPIkVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFDEptsALdpeLVGEV 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 647806363 191 LfqkrcfGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03262  175 L------DVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGR 212
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 52-245 1.49e-13

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 72.87  E-value: 1.49e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS--------GFNPE-FTG--RDNV 120
Cdd:COG4988  352 ALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASwrrqiawvPQNPYlFAGtiRENL 431

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 ylnamLLGmTHDEVDERFDKIAAFADIGDY-------LDQPV----KTYSSGMLVRLAFA---VQvqiDPDILIVDEALA 186
Cdd:COG4988  432 -----RLG-RPDASDEELEAALEAAGLDEFvaalpdgLDTPLgeggRGLSGGQAQRLALAralLR---DAPLLLLDEPTA 502

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363 187 ---------VGDALFQkrcfgrieklLSDGVTLLFVSHDQESVRtLTNRAILLKGGREVSMGSASQVL 245
Cdd:COG4988  503 hldaeteaeILQALRR----------LAKGRTVILITHRLALLA-QADRILVLDDGRIVEQGTHEELL 559
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 52-267 2.27e-13

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 70.99  E-value: 2.27e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRvaALLELGSG---------------FN--PEF 114
Cdd:PRK11153  20 ALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQ--DLTALSEKelrkarrqigmifqhFNllSSR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGD-ALFQ 193
Cdd:PRK11153  98 TVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLLCDEATSALDpATTR 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 194 KrcfgrIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD---------YRKLLHQEESDY 259
Cdd:PRK11153 178 S-----ILELLKDinrelGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHpkhpltrefIQSTLHLDLPED 252


                 ....*...
gi 647806363 260 FSRLMQPT 267
Cdd:PRK11153 253 YLARLQAE 260
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 53-277 2.59e-13

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 72.01  E-value: 2.59e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALL------ELGSGFNPE-------FTGRDN 119
Cdd:PRK15439  27 LKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLtpakahQLGIYLVPQepllfpnLSVKEN 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 VylnamLLGMTHDEVDERfdKIAA-FADIGDYLDQPVKTYSsgmlvrLAFAVQ--VQI------DPDILIVDEALAVGDA 190
Cdd:PRK15439 107 I-----LFGLPKRQASMQ--KMKQlLAALGCQLDLDSSAGS------LEVADRqiVEIlrglmrDSRILILDEPTASLTP 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 191 LFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSasqvlldyrklLHQEESDYFSRLMQPTADK 270
Cdd:PRK15439 174 AETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGK-----------TADLSTDDIIQAITPAARE 242


                 ....*..
gi 647806363 271 AQASASQ 277
Cdd:PRK15439 243 KSLSASQ 249
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 53-242 4.98e-13

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 68.23  E-value: 4.98e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR---------VAALLELGSGFN-------PEFTG 116
Cdd:COG4181   28 LKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQdlfaldedaRARLRARHVGFVfqsfqllPTLTA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 RDNVYLNAMLLGMthdevDERFDKIAAFAD---IGDYLDQPVKTYSSG-----MLVRlAFAVQvqidPDILIVDE----- 183
Cdd:COG4181  108 LENVMLPLELAGR-----RDARARARALLErvgLGHRLDHYPAQLSGGeqqrvALAR-AFATE----PAILFADEptgnl 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 184 ----ALAVGDALFQKRcfgRiekllSDGVTLLFVSHDQEsvrtLTNRA---ILLKGGREVSMGSAS 242
Cdd:COG4181  178 daatGEQIIDLLFELN---R-----ERGTTLVLVTHDPA----LAARCdrvLRLRAGRLVEDTAAT 231
Wzt_C pfam14524
Wzt C-terminal domain; This domain is found at the C-terminus of the Wzt protein. The crystal ...
 314-466 5.64e-13

Wzt C-terminal domain; This domain is found at the C-terminus of the Wzt protein. The crystal structure of C-Wzt(O9a) reveals a beta sandwich with an immunoglobulin-like topology that contains the O-antigenic polysaccharide binding pocket. This domain is often associated with the ABC-transporter domain.


Pssm-ID: 464200  Cd Length: 141  Bit Score: 66.20  E-value: 5.64e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  314 FGDGGVEVLSVSTFGVDDEPCAVFYPGDVIRIRVDCVSHINTDCINVGVRIRSREGIKMYSWGTLNQDMQVLAglregel 393
Cdd:pfam14524   3 YGSGEAEIIDVELLDEDGKPTNTFESGEEVTLRIKVRFHEDVEDPIFGFTIKDRLGQEVFGTNTFLEGKSLGA------- 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 647806363  394 fwkrqLTGGEQFHVWLECDCSLGSNLYEIQASISYEGKPDYSAQrILHWKDEAAFFQTLMRqDEYFFGGVSDL 466
Cdd:pfam14524  76 -----LKAGEVVEVEFRFKLNLQPGEYLLSVAIEDADGEQHEHV-VYDWLDDALVFEVGVS-SKNVFVGLVDL 141
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 53-192 7.00e-13

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 67.59  E-value: 7.00e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS---------GFNPEFTGRDNVYLN 123
Cdd:PRK13539  18 FSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEachylghrnAMKPALTVAENLEFW 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 647806363 124 AMLLGMTHDEVDErfdKIAAFaDIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE---AL-AVGDALF 192
Cdd:PRK13539  98 AAFLGGEELDIAA---ALEAV-GLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEptaALdAAAVALF 166
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
53-265 7.20e-13

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 68.50  E-value: 7.20e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV---------ETRGRVAALLELGSGF-NPE----FTGRD 118
Cdd:PRK13638  17 LKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVlwqgkpldySKRGLLALRQQVATVFqDPEqqifYTDID 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 -NVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCF 197
Cdd:PRK13638  97 sDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMI 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 198 GRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV-----LLDYRKL-------LHQE--------ES 257
Cdd:PRK13638 177 AIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVfacteAMEQAGLtqpwlvkLHTQlglplcktET 256


                 ....*...
gi 647806363 258 DYFSRLMQ 265
Cdd:PRK13638 257 EFFHRMQK 264
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 53-255 7.36e-13

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 68.03  E-value: 7.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS-----GFNPEftgrDNVYLNAML- 126
Cdd:cd03253   17 LKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSlrraiGVVPQ----DTVLFNDTIg 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 127 -------LGMTHDEVDErfdkIAAFADIGDYLDQPVKTY-----------SSGMLVRLAFAVQVQIDPDILIVDEALAVG 188
Cdd:cd03253   93 ynirygrPDATDEEVIE----AAKAAQIHDKIMRFPDGYdtivgerglklSGGEKQRVAIARAILKNPPILLLDEATSAL 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 647806363 189 DALFQKRCFGRIEKlLSDGVTLLFVSHdqeSVRTLTN--RAILLKGGREVSMGSASQVLLD---YRKLLHQE 255
Cdd:cd03253  169 DTHTEREIQAALRD-VSKGRTTIVIAH---RLSTIVNadKIIVLKDGRIVERGTHEELLAKgglYAEMWKAQ 236
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
52-247 7.61e-13

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 70.20  E-value: 7.61e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALL------ELGSGF-------NPEFTGRD 118
Cdd:PRK09700  20 ALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLdhklaaQLGIGIiyqelsvIDELTVLE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 NVYLNAMLLG--MTHDEVDERFDKIAA-----FADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAvgdAL 191
Cdd:PRK09700 100 NLYIGRHLTKkvCGVNIIDWREMRVRAammllRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTS---SL 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 192 FQKRC---FGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK09700 177 TNKEVdylFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDVSND 235
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 48-239 9.45e-13

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 67.13  E-value: 9.45e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  48 REYWALENISFD--IRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-----------VAALLELGSGFnPEF 114
Cdd:cd03298    7 RFSYGEQPMHFDltFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVdvtaappadrpVSMLFQENNLF-AHL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLnAMLLGMTHDEVD-ERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFA-VQVQIDPdILIVDEAL-AVGDAL 191
Cdd:cd03298   86 TVEQNVGL-GLSPGLKLTAEDrQAIEVALARVGLAGLEKRLPGELSGGERQRVALArVLVRDKP-VLLLDEPFaALDPAL 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 647806363 192 FQKrcfgrIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMG 239
Cdd:cd03298  164 RAE-----MLDLVLDlhaetKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
54-185 1.20e-12

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 66.75  E-value: 1.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  54 ENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV---------AALLELG--SGFNPEFTGRDNVYL 122
Cdd:PRK13538  18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPirrqrdeyhQDLLYLGhqPGIKTELTALENLRF 97

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 647806363 123 NAMLlgmtHDEVDErFDKIAAFADIG--DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEAL 185
Cdd:PRK13538  98 YQRL----HGPGDD-EALWEALAQVGlaGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPF 157
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 53-264 1.34e-12

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 70.32  E-value: 1.34e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363    53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAallelgsgFNPEF------TGRDNVylnamL 126
Cdd:TIGR01271  442 LKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRIS--------FSPQTswimpgTIKDNI-----I 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   127 LGMTHDEVDERF--------DKIAAFADIGDY-LDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCF 197
Cdd:TIGR01271  509 FGLSYDEYRYTSvikacqleEDIALFPEKDKTvLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFTHLDVVTEKEIF 588

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363   198 GR-IEKLLSDGVTLLFVSHDQESVRtlTNRAILLKGGREVSMGSASQvlldyrklLHQEESDYFSRLM 264
Cdd:TIGR01271  589 EScLCKLMSNKTRILVTSKLEHLKK--ADKILLLHEGVCYFYGTFSE--------LQAKRPDFSSLLL 646
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 52-216 1.85e-12

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 69.31  E-value: 1.85e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS-----GFNPE----F--TGRDNV 120
Cdd:TIGR02868 350 VLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEvrrrvSVCAQdahlFdtTVRENL 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  121 YLNAmllgmtHDEVDERFDKIAAFADIGDY-------LDQPV----KTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGD 189
Cdd:TIGR02868 430 RLAR------PDATDEELWAALERVGLADWlralpdgLDTVLgeggARLSGGERQRLALARALLADAPILLLDEPTEHLD 503

                         170       180
                  ....*....|....*....|....*....
gi 647806363  190 ALFQKRCfgrIEKLLS--DGVTLLFVSHD 216
Cdd:TIGR02868 504 AETADEL---LEDLLAalSGRTVVLITHH 529
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 51-234 1.89e-12

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 65.32  E-value: 1.89e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGrvAALLELGSGfnpEFtgRDNV-YL--NAMLL 127
Cdd:cd03246   16 PVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDG--ADISQWDPN---EL--GDHVgYLpqDDELF 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 128 GMThdevderfdkiaaFADIgdyldqpvkTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDG 207
Cdd:cd03246   89 SGS-------------IAEN---------ILSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAAG 146

                        170       180
                 ....*....|....*....|....*..
gi 647806363 208 VTLLFVSHDQESVRtLTNRAILLKGGR 234
Cdd:cd03246  147 ATRIVIAHRPETLA-SADRILVLEDGR 172
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
45-240 2.26e-12

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 69.04  E-value: 2.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  45 SYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-------------ETRGRVA-----ALLel 106
Cdd:COG1132  348 SYPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRIlidgvdirdltleSLRRQIGvvpqdTFL-- 425

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 107 gsgfnpeFTG--RDNVylnamLLGM---THDEVDErfdkIAAFADIGDY-------LDQPV----KTYSSGMLVRLAFA- 169
Cdd:COG1132  426 -------FSGtiRENI-----RYGRpdaTDEEVEE----AAKAAQAHEFiealpdgYDTVVgergVNLSGGQRQRIAIAr 489

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 170 VQVQiDPDILIVDEALA----VGDALFQKrcfgRIEKLLSdGVTLLFVSHdqesvR--TLTN--RAILLKGGREVSMGS 240
Cdd:COG1132  490 ALLK-DPPILILDEATSaldtETEALIQE----ALERLMK-GRTTIVIAH-----RlsTIRNadRILVLDDGRIVEQGT 557
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 49-234 2.46e-12

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 65.03  E-value: 2.46e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLE-----LGSGFNPEftgrdnVYLN 123
Cdd:cd03247   14 EQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEkalssLISVLNQR------PYLF 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 124 AMLLGmthDEVDERFdkiaafadigdyldqpvktySSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKL 203
Cdd:cd03247   88 DTTLR---NNLGRRF--------------------SGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQLLSLIFEV 144

                        170       180       190
                 ....*....|....*....|....*....|.
gi 647806363 204 LSDGvTLLFVSHDQESVRTLtNRAILLKGGR 234
Cdd:cd03247  145 LKDK-TLIWITHHLTGIEHM-DKILFLENGK 173
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 52-245 2.54e-12

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 67.86  E-value: 2.54e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAAL----LELGSGF---N----PEFTGRDNV 120
Cdd:COG1118   17 LLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFTnlppRERRVGFvfqHyalfPHMTVAENI 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 ylnamLLGMTH-----DEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE---ALavgDALF 192
Cdd:COG1118   97 -----AFGLRVrppskAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEpfgAL---DAKV 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363 193 QKrcfgRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:COG1118  169 RK----ELRRWLRRlhdelGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVY 222
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
55-245 2.65e-12

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 66.32  E-value: 2.65e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  55 NISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-----------VAALlelgsgFN-----PEFTGRD 118
Cdd:COG3840   17 RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQdltalppaerpVSML------FQennlfPHLTVAQ 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 NVYLnAMLLGMTHDEVD-ERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFA-VQVQIDPdILIVDEAL-AVGDALfqkr 195
Cdd:COG3840   91 NIGL-GLRPGLKLTAEQrAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALArCLVRKRP-ILLLDEPFsALDPAL---- 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 196 cfgRIE--KLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:COG3840  165 ---RQEmlDLVDElcrerGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALL 218
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 53-245 3.42e-12

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 66.11  E-value: 3.42e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIaPTVGTVETRGRVAALLELGS-----GF-----NPEFtgrdNV-- 120
Cdd:PRK03695  12 LGPLSAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFAGQPLEAWSAAElarhrAYlsqqqTPPF----AMpv 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 --YLNAMLLGMTH-DEVDERFDKIAAFADIGDYLDQPVKTYSSG--MLVRLAfAVQVQIDPDI------LIVDEALAVGD 189
Cdd:PRK03695  87 fqYLTLHQPDKTRtEAVASALNEVAEALGLDDKLGRSVNQLSGGewQRVRLA-AVVLQVWPDInpagqlLLLDEPMNSLD 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363 190 ALFQKRCFGRIEKLLSDGVTLLFVSHDQEsvRTL--TNRAILLKGGREVSMGSASQVL 245
Cdd:PRK03695 166 VAQQAALDRLLSELCQQGIAVVMSSHDLN--HTLrhADRVWLLKQGKLLASGRRDEVL 221
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
52-234 3.77e-12

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 67.66  E-value: 3.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVA-----------------ALLelgsgfnPEF 114
Cdd:PRK09452  29 VISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDIthvpaenrhvntvfqsyALF-------PHM 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVylnAMLLGMT---HDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDAL 191
Cdd:PRK09452 102 TVFENV---AFGLRMQktpAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDYK 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 647806363 192 FQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:PRK09452 179 LRKQMQNELKALQRKlGITFVFVTHDQEEALTMSDRIVVMRDGR 222
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 52-261 3.89e-12

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 66.34  E-value: 3.89e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLI------------TGTI--------APTVGTVETRGrvaallELGSGF- 110
Cdd:PRK14239  20 ALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrmndlnpevtiTGSIvynghniySPRTDTVDLRK------EIGMVFq 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 111 --NP-EFTGRDNVYLNAMLLGM----THDEVDERFDKIAAFAD-IGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVD 182
Cdd:PRK14239  94 qpNPfPMSIYENVVYGLRLKGIkdkqVLDEAVEKSLKGASIWDeVKDRLHDSALGLSGGQQQRVCIARVLATSPKIILLD 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 183 EALAVGDALFQkrcfGRIEK---LLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLDYRkllHQEESDY 259
Cdd:PRK14239 174 EPTSALDPISA----GKIEEtllGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNPK---HKETEDY 246


                 ..
gi 647806363 260 FS 261
Cdd:PRK14239 247 IS 248
cbiO PRK13649
energy-coupling factor transporter ATPase;
52-247 4.04e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 66.69  E-value: 4.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVET-----------------RGRVAALLELGSGFNPEF 114
Cdd:PRK13649  22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVddtlitstsknkdikqiRKKVGLVFQFPESQLFEE 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYL-DQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQ 193
Cdd:PRK13649 102 TVLKDVAFGPQNFGVSQEEAEALAREKLALVGISESLfEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKGR 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 647806363 194 KRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK13649 182 KELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
54-244 5.15e-12

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 65.94  E-value: 5.15e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  54 ENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV----------------ETRGRVAALLELGSGF------- 110
Cdd:PRK11831  24 DNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEIlfdgenipamsrsrlyTVRKRMSMLFQSGALFtdmnvfd 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 111 NPEFTGRDNVYLNAMLLgmtHDEVderFDKIAAFADIGDYLDQPVKtYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:PRK11831 104 NVAYPLREHTQLPAPLL---HSTV---MMKLEAVGLRGAAKLMPSE-LSGGMARRAALARAIALEPDLIMFDEPFVGQDP 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 191 LfqkrCFGRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK11831 177 I----TMGVLVKLISElnsalGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 51-251 7.16e-12

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 64.94  E-value: 7.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS-----GFNPE----FTG--RDN 119
Cdd:cd03251   16 PVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASlrrqiGLVSQdvflFNDtvAEN 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 VYLNAmlLGMTHDEVdERFDKIAAFADIGDYLDQPVKT--------YSSGMLVRLAFAVQVQIDPDILIVDEALAVGDAL 191
Cdd:cd03251   96 IAYGR--PGATREEV-EEAARAANAHEFIMELPEGYDTvigergvkLSGGQRQRIAIARALLKDPPILILDEATSALDTE 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 647806363 192 FQKRCFGRIEKLLSDGVTLLfVSHDQESVRTlTNRAILLKGGREVSMGSASQvLLD----YRKL 251
Cdd:cd03251  173 SERLVQAALERLMKNRTTFV-IAHRLSTIEN-ADRIVVLEDGKIVERGTHEE-LLAqggvYAKL 233
cbiO PRK13640
energy-coupling factor transporter ATPase;
52-240 8.78e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 65.59  E-value: 8.78e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAP-----TVGTV-----------ETRGRVAALLElgsgfNPeft 115
Cdd:PRK13640  22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPddnpnSKITVdgitltaktvwDIREKVGIVFQ-----NP--- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 grDNVYLNAML-----LGMTHDEVD-ERFDKIA--AFADIG--DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEAL 185
Cdd:PRK13640  94 --DNQFVGATVgddvaFGLENRAVPrPEMIKIVrdVLADVGmlDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDEST 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 186 AVGDALFQKRCFGRIEKLLSD-GVTLLFVSHDQESVrTLTNRAILLKGGREVSMGS 240
Cdd:PRK13640 172 SMLDPAGKEQILKLIRKLKKKnNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGS 226
cbiO PRK13642
energy-coupling factor transporter ATPase;
53-245 1.26e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 65.11  E-value: 1.26e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG-RVAA------LLELGSGF-NP--EFTG---RDN 119
Cdd:PRK13642  23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGeLLTAenvwnlRRKIGMVFqNPdnQFVGatvEDD 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 120 VYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGR 199
Cdd:PRK13642 103 VAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRV 182

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 647806363 200 IEKLLSD-GVTLLFVSHDQESVRTlTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK13642 183 IHEIKEKyQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELF 228
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 53-264 1.28e-11

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 65.26  E-value: 1.28e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAallelgsgFNPEF------TGRDNVylnamL 126
Cdd:cd03291   53 LKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGRIS--------FSSQFswimpgTIKENI-----I 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 127 LGMTHDEVDERF--------DKIAAFADiGDY--LDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRC 196
Cdd:cd03291  120 FGVSYDEYRYKSvvkacqleEDITKFPE-KDNtvLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEKEI 198

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 197 FGR-IEKLLSDGvTLLFVSHDQESVRTlTNRAILLKGGREVSMGSASQvlldyrklLHQEESDYFSRLM 264
Cdd:cd03291  199 FEScVCKLMANK-TRILVTSKMEHLKK-ADKILILHEGSSYFYGTFSE--------LQSLRPDFSSKLM 257
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 52-234 1.59e-11

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 62.83  E-value: 1.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE------TRGRVAALLELGSGFNPE----------FT 115
Cdd:cd03215   15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITldgkpvTRRSPRDAIRAGIAYVPEdrkreglvldLS 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 GRDNVYLNAMLlgmthdevderfdkiaafadigdyldqpvktySSGMLVRLAFAVQVQIDPDILIVDE---ALAVG--DA 190
Cdd:cd03215   95 VAENIALSSLL--------------------------------SGGNQQKVVLARWLARDPRVLILDEptrGVDVGakAE 142

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 647806363 191 LFQkrcfgRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:cd03215  143 IYR-----LIRELADAGKAVLLISSELDELLGLCDRILVMYEGR 181
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
55-234 2.16e-11

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 65.05  E-value: 2.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  55 NISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGT----------VETRGRVAALLELGSGFNPEFTGRDNVYLNA 124
Cdd:PRK11000  21 DINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDlfigekrmndVPPAERGVGMVFQSYALYPHLSVAENMSFGL 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 125 MLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALF--QKRC-FGRIE 201
Cdd:PRK11000 101 KLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALrvQMRIeISRLH 180

                        170       180       190
                 ....*....|....*....|....*....|...
gi 647806363 202 KLLsdGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:PRK11000 181 KRL--GRTMIYVTHDQVEAMTLADKIVVLDAGR 211
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 53-245 2.17e-11

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 63.71  E-value: 2.17e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGtIAPTVGTVETRGRvaALlelgSGFNPEFTGRDNVYLN-------AM 125
Cdd:COG4138   12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAG-LLPGQGEILLNGR--PL----SDWSAAELARHRAYLSqqqsppfAM 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 126 L------LGM----THDEVDERFDKIAAFADIGDYLDQPVKTYSSG--MLVRLAfAVQVQIDPDI------LIVDEALAV 187
Cdd:COG4138   85 PvfqylaLHQpagaSSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGewQRVRLA-AVLLQVWPTInpegqlLLLDEPMNS 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 188 GDALFQKRCFGRIEKLLSDGVTLLFVSHDQEsvRTL--TNRAILLKGGREVSMGSASQVL 245
Cdd:COG4138  164 LDVAQQAALDRLLRELCQQGITVVMSSHDLN--HTLrhADRVWLLKQGKLVASGETAEVM 221
cbiO PRK13641
energy-coupling factor transporter ATPase;
53-247 2.27e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 64.47  E-value: 2.27e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVET-----------------RGRVAALLELGSGFNPEFT 115
Cdd:PRK13641  23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIagyhitpetgnknlkklRKKVSLVFQFPEAQLFENT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 GRDNVYLNAMLLGMTHDEVDERfdKIAAFADIG---DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALF 192
Cdd:PRK13641 103 VLKDVEFGPKNFGFSEDEAKEK--ALKWLKKVGlseDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEG 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 647806363 193 QKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK13641 181 RKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSD 235
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 52-244 2.47e-11

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 65.50  E-value: 2.47e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKST----LLQLIT--GTIAPTVGTVETRGRvAALLEL-----------GSGFNPef 114
Cdd:PRK15134 301 VVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLINsqGEIWFDGQPLHNLNR-RQLLPVrhriqvvfqdpNSSLNP-- 377

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 tgRDNVY------LNAMLLGMTHDEVDERFdkIAAFADIGdyLDQPVK-----TYSSGMLVRLAFAVQVQIDPDILIVDE 183
Cdd:PRK15134 378 --RLNVLqiieegLRVHQPTLSAAQREQQV--IAVMEEVG--LDPETRhrypaEFSGGQRQRIAIARALILKPSLIILDE 451

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 647806363 184 ALAVGDALFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK15134 452 PTSSLDKTVQAQILALLKSLQQKhQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERV 513
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
53-234 2.85e-11

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 63.30  E-value: 2.85e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR------VAALLELGS---GFN-------PEFTG 116
Cdd:PRK11629  25 LHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQpmsklsSAAKAELRNqklGFIyqfhhllPDFTA 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 RDNVYLNAMLLGMTHDEVDER-FDKIAAFAdigdyLDQPVKTYSS----GMLVRLAFAVQVQIDPDILIVDEALAVGDAL 191
Cdd:PRK11629 105 LENVAMPLLIGKKKPAEINSRaLEMLAAVG-----LEHRANHRPSelsgGERQRVAIARALVNNPRLVLADEPTGNLDAR 179

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 647806363 192 FQKRCFGRIEKL-LSDGVTLLFVSHDQESVRTLtNRAILLKGGR 234
Cdd:PRK11629 180 NADSIFQLLGELnRLQGTAFLVVTHDLQLAKRM-SRQLEMRDGR 222
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 49-247 3.37e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 64.10  E-value: 3.37e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-----------------------------ETRGR 99
Cdd:PRK13631  38 ELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdiyigdkknnhelitnpyskkiknfkELRRR 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 100 VAALLELgsgfnPEF-----TGRDNVYLNAMLLGMTHDEVDERfdkiAAFADIG-----DYLDQPVKTYSSGMLVRLAFA 169
Cdd:PRK13631 118 VSMVFQF-----PEYqlfkdTIEKDIMFGPVALGVKKSEAKKL----AKFYLNKmglddSYLERSPFGLSGGQKRRVAIA 188

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363 170 VQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK13631 189 GILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTD 266
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 52-246 5.32e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 63.28  E-value: 5.32e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG------------RVAALLELGSG---FNPefTG 116
Cdd:PRK13652  19 ALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGepitkenirevrKFVGLVFQNPDdqiFSP--TV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 RDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRC 196
Cdd:PRK13652  97 EQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKEL 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 647806363 197 FGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLL 246
Cdd:PRK13652 177 IDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFL 227
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 51-183 6.21e-11

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 62.29  E-value: 6.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTI---APTVGTV----------ETRGRVAALLELGSgFNPEFTGR 117
Cdd:cd03234   21 RILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVeggGTTSGQIlfngqprkpdQFQKCVAYVRQDDI-LLPGLTVR 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 647806363 118 DNVYLNAMLLGMTH------DEVDERFD-KIAAFADIGDYLdqpVKTYSSGMLVRLAFAVQVQIDPDILIVDE 183
Cdd:cd03234  100 ETLTYTAILRLPRKssdairKKRVEDVLlRDLALTRIGGNL---VKGISGGERRRVSIAVQLLWDPKVLILDE 169
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 53-227 7.88e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 61.50  E-value: 7.88e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG------RVAALLEL-----GSGFNPEFTGRDNVY 121
Cdd:PRK13540  17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERqsikkdLCTYQKQLcfvghRSGINPYLTLRENCL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 LNaMLLGMTHDEVDErfdkIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIE 201
Cdd:PRK13540  97 YD-IHFSPGAVGITE----LCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKIQ 171

                        170       180
                 ....*....|....*....|....*.
gi 647806363 202 KLLSDGVTLLFVSHDQESVrtltNRA 227
Cdd:PRK13540 172 EHRAKGGAVLLTSHQDLPL----NKA 193
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 59-232 9.04e-11

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 62.04  E-value: 9.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  59 DIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAAllelgsgFNPEFTGRD-NVYLNAMLLGMTHDEVDER 137
Cdd:cd03237   21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS-------YKPQYIKADyEGTVRDLLSSITKDFYTHP 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 138 FDK--IAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDA---LFQKRCFGRIekLLSDGVTLLF 212
Cdd:cd03237   94 YFKteIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVeqrLMASKVIRRF--AENNEKTAFV 171

                        170       180
                 ....*....|....*....|
gi 647806363 213 VSHDQESVRTLTNRAILLKG 232
Cdd:cd03237  172 VEHDIIMIDYLADRLIVFEG 191
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 52-234 1.21e-10

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 63.51  E-value: 1.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE------TRGRVAALLELGSGFNPE----------FT 115
Cdd:COG3845  273 ALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRldgediTGLSPRERRRLGVAYIPEdrlgrglvpdMS 352

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 GRDNvylnaMLLGMTHDEVDER-----FDKIAAFAD--IGDY------LDQPVKTYSSGMLVRLAFAVQVQIDPDILIVD 182
Cdd:COG3845  353 VAEN-----LILGRYRRPPFSRggfldRKAIRAFAEelIEEFdvrtpgPDTPARSLSGGNQQKVILARELSRDPKLLIAA 427

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 647806363 183 E---ALAVGDALFQKRcfgRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:COG3845  428 QptrGLDVGAIEFIHQ---RLLELRDAGAAVLLISEDLDEILALSDRIAVMYEGR 479
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
53-241 1.44e-10

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 62.43  E-value: 1.44e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG----------RVAALLELGSGFNPEFTGRDNVYL 122
Cdd:PRK11432  22 IDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGedvthrsiqqRDICMVFQSYALFPHMSLGENVGY 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 123 NAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEK 202
Cdd:PRK11432 102 GLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRE 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 647806363 203 LLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSA 241
Cdd:PRK11432 182 LQQQfNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSP 221
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 52-245 1.56e-10

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 63.20  E-value: 1.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGSGFNP-EFTGRDNVYLNAMLL--- 127
Cdd:TIGR02203 347 ALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASLRRQvALVSQDVVLFNDTIAnni 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  128 --GMTHDEVDERFDKIAAFADIGDY-------LDQPVKT----YSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQK 194
Cdd:TIGR02203 427 ayGRTEQADRAEIERALAAAYAQDFvdklplgLDTPIGEngvlLSGGQRQRLAIARALLKDAPILILDEATSALDNESER 506

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 647806363  195 RCFGRIEKLLsDGVTLLFVSHDQESVRTlTNRAILLKGGREVSMGSASQVL 245
Cdd:TIGR02203 507 LVQAALERLM-QGRTTLVIAHRLSTIEK-ADRIVVMDDGRIVERGTHNELL 555
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 53-247 1.64e-10

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 61.30  E-value: 1.64e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV--------------ETRGRVAALLE----LGSGFN--P 112
Cdd:PRK11264  19 LHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgditidtarslsQQKGLIRQLRQhvgfVFQNFNlfP 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 113 EFTGRDNVYLNAMLL-GMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDAL 191
Cdd:PRK11264  99 HRTVLENIIEGPVIVkGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPE 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 192 FQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK11264 179 LVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFAD 234
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 54-244 1.76e-10

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 61.25  E-value: 1.76e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  54 ENISFDIRKGEAFGIVGRNGSGKS----TLLQLITGTIAPTVGTV----------ETRGRVAALLELG--SGFNPEFTGR 117
Cdd:PRK10418  20 HGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVlldgkpvapcALRGRKIATIMQNprSAFNPLHTMH 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVYLNAMLLGMTHDevDERFdkIAAFADIGdyLDQP---VKTY----SSGMLVRLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:PRK10418 100 THARETCLALGKPAD--DATL--TAALEAVG--LENAarvLKLYpfemSGGMLQRMMIALALLCEAPFIIADEPTTDLDV 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 647806363 191 LFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK10418 174 VAQARILDLLESIVQKrALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETL 228
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 52-242 2.04e-10

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 60.80  E-value: 2.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR---------VAALLEL----GSGFN-----PE 113
Cdd:PRK11124  17 ALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNhfdfsktpsDKAIRELrrnvGMVFQqynlwPH 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 114 FTGRDNVYLNAM-LLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALF 192
Cdd:PRK11124  97 LTVQQNLIEAPCrVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEI 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 647806363 193 QKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSAS 242
Cdd:PRK11124 177 TAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDAS 226
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 52-221 2.55e-10

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 62.30  E-value: 2.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGSG-----------FNPEFTGRDNV 120
Cdd:TIGR02857 337 ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWrdqiawvpqhpFLFAGTIAENI 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  121 YLNAmlLGMTHDEVDERFDKIAA---FADIGDYLDQPV----KTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQ 193
Cdd:TIGR02857 417 RLAR--PDASDAEIREALERAGLdefVAALPQGLDTPIgeggAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETE 494

                         170       180
                  ....*....|....*....|....*...
gi 647806363  194 KRCFGRIEKlLSDGVTLLFVSHDQESVR 221
Cdd:TIGR02857 495 AEVLEALRA-LAQGRTVLLVTHRLALAA 521
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 53-234 3.40e-10

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 60.46  E-value: 3.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGtvetrgrvaallELGSGFNPEFTGRDNVYL---NAMLLGM 129
Cdd:PRK11247  28 LNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAG------------ELLAGTAPLAEAREDTRLmfqDARLLPW 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 130 TH--DEV------DERFDKIAAFADIG--DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGR 199
Cdd:PRK11247  96 KKviDNVglglkgQWRDAALQALAAVGlaDRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDL 175

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 647806363 200 IEKL-LSDGVTLLFVSHD-QESVrTLTNRAILLKGGR 234
Cdd:PRK11247 176 IESLwQQHGFTVLLVTHDvSEAV-AMADRVLLIEEGK 211
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 53-247 5.27e-10

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 59.52  E-value: 5.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLEL------GSGFNPEFTG---RDNVYLN 123
Cdd:PRK10895  19 VEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLhararrGIGYLPQEASifrRLSVYDN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 124 AMLL-----GMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFG 198
Cdd:PRK10895  99 LMAVlqirdDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKR 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 647806363 199 RIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK10895 179 IIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQD 227
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 53-277 6.15e-10

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 61.34  E-value: 6.15e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVEtrgrVAALLELG--SGFNPEFTGRDNVYLNaMLLGMT 130
Cdd:PRK10636 328 LDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIG----LAKGIKLGyfAQHQLEFLRADESPLQ-HLARLA 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 131 HDEVDERF-DKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEA-----LAVGDALfqkrcfgrIEKLL 204
Cdd:PRK10636 403 PQELEQKLrDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPtnhldLDMRQAL--------TEALI 474

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 205 SDGVTLLFVSHDQESVRTLTNRAILLKGGR-EVSMGSasqvLLDYRKLL---HQEESDYFSRLMQPTADKAQASASQ 277
Cdd:PRK10636 475 DFEGALVVVSHDRHLLRSTTDDLYLVHDGKvEPFDGD----LEDYQQWLsdvQKQENQTDEAPKENNANSAQARKDQ 547
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 52-244 6.17e-10

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 60.49  E-value: 6.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLItgtiaptVGTVE-TRGRVAALlelgsgfnpeftGRDnvylnamLLGMT 130
Cdd:PRK15079  36 AVDGVTLRLYEGETLGVVGESGCGKSTFARAI-------IGLVKaTDGEVAWL------------GKD-------LLGMK 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 131 HDEV-DERFDKIAAFAD----------IGDYLDQPVKTY----------------------------------SSGMLVR 165
Cdd:PRK15079  90 DDEWrAVRSDIQMIFQDplaslnprmtIGEIIAEPLRTYhpklsrqevkdrvkammlkvgllpnlinryphefSGGQCQR 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 166 LAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK15079 170 IGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREmGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEV 249
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
52-243 6.62e-10

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 61.19  E-value: 6.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR------VAALLELGSGFNPE----------FT 115
Cdd:COG1129  267 VVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKpvrirsPRDAIRAGIAYVPEdrkgeglvldLS 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 116 GRDNVYLNAMLLGMTHDEVDERfdKIAAFAD--IGDY------LDQPVKTYSSG-----MLVR-LAfavqvqIDPDILIV 181
Cdd:COG1129  347 IRENITLASLDRLSRGGLLDRR--RERALAEeyIKRLriktpsPEQPVGNLSGGnqqkvVLAKwLA------TDPKVLIL 418

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 182 DE--------------ALavgdalfqkrcfgrIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR---EVSMGSASQ 243
Cdd:COG1129  419 DEptrgidvgakaeiyRL--------------IRELAAEGKAVIVISSELPELLGLSDRILVMREGRivgELDREEATE 483
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 52-247 7.96e-10

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 59.65  E-value: 7.96e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAA-------LLEL----GSGFN-PE---F-- 114
Cdd:PRK13634  22 ALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITagkknkkLKPLrkkvGIVFQfPEhqlFee 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIG-DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQ 193
Cdd:PRK13634 102 TVEKDICFGPMNFGVSEEDAKQKAREMIELVGLPeELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGR 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 647806363 194 KRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK13634 182 KEMMEMFYKLHKEkGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFAD 236
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 52-99 8.20e-10

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 59.33  E-value: 8.20e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR 99
Cdd:COG1101   21 ALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGK 68
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 55-234 9.78e-10

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 60.45  E-value: 9.78e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  55 NISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV-----ETRGR-VAALLELGSGFNPEFTGRDNVYLNAML-- 126
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRImlngkEINALsTAQRLARGLVYLPEDRQSSGLYLDAPLaw 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 127 --LGMTHDE------------VDERFDKIAA--FADIgdylDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:PRK15439 361 nvCALTHNRrgfwikparenaVLERYRRALNikFNHA----EQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDV 436

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 647806363 191 LFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:PRK15439 437 SARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGE 480
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 53-227 1.16e-09

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 58.19  E-value: 1.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLelgsgfNPEfTGRDNVYLNA---MLLGM 129
Cdd:PRK10247  23 LNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTL------KPE-IYRQQVSYCAqtpTLFGD 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 130 T------------HDEVDER--FDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKR 195
Cdd:PRK10247  96 TvydnlifpwqirNQQPDPAifLDDLERFALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHN 175

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 647806363 196 CFGRIEKLLSD-GVTLLFVSHDQ------ESVRTLTNRA 227
Cdd:PRK10247 176 VNEIIHRYVREqNIAVLWVTHDKdeinhaDKVITLQPHA 214
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 44-261 1.20e-09

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 59.03  E-value: 1.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  44 SSYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQ-------LITG-------------TIAPTVGTVETRGRVAAL 103
Cdd:PRK14243  17 NVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRcfnrlndLIPGfrvegkvtfhgknLYAPDVDPVEVRRRIGMV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 104 LELGSGFNPEFtgRDNVYLNAMLLGMT--HDEVDERFDKIAAFAD-IGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILI 180
Cdd:PRK14243  97 FQKPNPFPKSI--YDNIAYGARINGYKgdMDELVERSLRQAALWDeVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEVIL 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 181 VDEALAVGDALFQKrcfgRIEKL---LSDGVTLLFVSHD-QESVRT-----LTNRAILLKGGREVSMGSASQVLLDYRKL 251
Cdd:PRK14243 175 MDEPCSALDPISTL----RIEELmheLKEQYTIIIVTHNmQQAARVsdmtaFFNVELTEGGGRYGYLVEFDRTEKIFNSP 250

                        250
                 ....*....|
gi 647806363 252 LHQEESDYFS 261
Cdd:PRK14243 251 QQQATRDYVS 260
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
57-245 1.52e-09

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 58.05  E-value: 1.52e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  57 SFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-----------VAALLELGSGFnPEFTGRDNVYLNam 125
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQdhtttppsrrpVSMLFQENNLF-SHLTVAQNIGLG-- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 126 L---LGMTHDEvDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFA---VQVQidPdILIVDEALAVGD-ALfqkrcfg 198
Cdd:PRK10771  96 LnpgLKLNAAQ-REKLHAIARQMGIEDLLARLPGQLSGGQRQRVALArclVREQ--P-ILLLDEPFSALDpAL------- 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 647806363 199 RIE--KLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK10771 165 RQEmlTLVSQvcqerQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELL 218
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 52-278 1.68e-09

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 59.70  E-value: 1.68e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKS----TLLQLITGTIAPTVGTVETRGRvaALLELG-------------------- 107
Cdd:COG4172   25 AVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQ--DLLGLSerelrrirgnriamifqepm 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 108 SGFNPEFTGRDNVYLNAML-LGMTHDEVDERFdkIAAFADIGdyLDQP---VKTY----SSGMLVRLAFAVQVQIDPDIL 179
Cdd:COG4172  103 TSLNPLHTIGKQIAEVLRLhRGLSGAAARARA--LELLERVG--IPDPerrLDAYphqlSGGQRQRVMIAMALANEPDLL 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 180 IVDE---ALavgDALFQKrcfgRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLL----D 247
Cdd:COG4172  179 IADEpttAL---DVTVQA----QILDLLKDlqrelGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAELFAapqhP 251

                        250       260       270
                 ....*....|....*....|....*....|..
gi 647806363 248 Y-RKLLHQEesdyfsrlmqPTADKAQASASQP 278
Cdd:COG4172  252 YtRKLLAAE----------PRGDPRPVPPDAP 273
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
52-245 1.79e-09

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 58.26  E-value: 1.79e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVaalLELG-----------------SGFNPEf 114
Cdd:PRK15112  28 AVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHP---LHFGdysyrsqrirmifqdpsTSLNPR- 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 tGRDNVYLNAMLLGMTHDEVDERFDKI-AAFADIG---DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:PRK15112 104 -QRISQILDFPLRLNTDLEPEQREKQIiETLRQVGllpDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDM 182

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 191 LFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK15112 183 SMRSQLINLMLELQEKqGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVL 238
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
60-183 1.92e-09

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 59.82  E-value: 1.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  60 IRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAallelgsgFNPEFTGRD---NVYlnaMLLGMTHDEVDE 136
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELKIS--------YKPQYIKPDydgTVE---DLLRSITDDLGS 430

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 647806363 137 RFDK--IAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE 183
Cdd:PRK13409 431 SYYKseIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDE 479
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 51-245 2.06e-09

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 57.55  E-value: 2.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLE------LGSGFNP-------EFTGR 117
Cdd:cd03218   14 KVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPmhkrarLGIGYLPqeasifrKLTVE 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVYLnamLLGMTHDEVDERFDKIAAFAD---IGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE------ALAVG 188
Cdd:cd03218   94 ENILA---VLEIRGLSKKEREEKLEELLEefhITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEpfagvdPIAVQ 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 189 DalFQKrcfgRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:cd03218  171 D--IQK----IIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIA 221
hmuV PRK13547
heme ABC transporter ATP-binding protein;
53-245 3.05e-09

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 57.91  E-value: 3.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGT--VETRGRVA------------------ALLELGSGFNP 112
Cdd:PRK13547  17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGGAPrgARVTGDVTlngeplaaidaprlarlrAVLPQAAQPAF 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 113 EFTGRDNV----YLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFA-VQVQIDPD--------IL 179
Cdd:PRK13547  97 AFSAREIVllgrYPHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFArVLAQLWPPhdaaqpprYL 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 180 IVDEALAVGDALFQKRCFGRIEKLLSD---GVtlLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK13547 177 LLDEPTAALDLAHQHRLLDTVRRLARDwnlGV--LAIVHDPNLAARHADRIAMLADGAIVAHGAPADVL 243
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 62-229 3.28e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.46  E-value: 3.28e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363    62 KGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVetrgrvaallelgsgfnpeftgrdnVYLNAmllgmthdevdERFDKI 141
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV-------------------------IYIDG-----------EDILEE 44

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   142 AAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQK------RCFGRIEKLLSDGVTLLFVSH 215
Cdd:smart00382  45 VLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEAllllleELRLLLLLKSEKNLTVILTTN 124

                          170
                   ....*....|....
gi 647806363   216 DQESVRTLTNRAIL 229
Cdd:smart00382 125 DEKDLGPALLRRRF 138
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
52-234 3.57e-09

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 56.81  E-value: 3.57e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALL----------ELGSGFNP-----EFTG 116
Cdd:PRK10908  17 ALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLknrevpflrrQIGMIFQDhhllmDRTV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 RDNVYLNAMLLGMTHDEVDERFDkiAAFADIGdYLDQ----PVKtYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALF 192
Cdd:PRK10908  97 YDNVAIPLIIAGASGDDIRRRVS--AALDKVG-LLDKaknfPIQ-LSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDAL 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 647806363 193 QKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:PRK10908 173 SEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGH 214
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 53-245 3.77e-09

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 57.16  E-value: 3.77e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTI--------------------APTVGTVETRGRVAALLELGSGFnP 112
Cdd:PRK14267  20 IKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLelneearvegevrlfgrniySPDVDPIEVRREVGMVFQYPNPF-P 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 113 EFTGRDNVYLNAMLLGM--THDEVDERFD----KIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALA 186
Cdd:PRK14267  99 HLTIYDNVAIGVKLNGLvkSKKELDERVEwalkKAALWDEVKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTA 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 647806363 187 VGDALFQKrcfgRIEKL---LSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK14267 179 NIDPVGTA----KIEELlfeLKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVF 236
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
52-234 5.33e-09

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 57.55  E-value: 5.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLE--------------LgsgfNPEFTGR 117
Cdd:PRK11650  19 VIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEpadrdiamvfqnyaL----YPHMSVR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 118 DNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDAlfQKRCF 197
Cdd:PRK11650  95 ENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDA--KLRVQ 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 647806363 198 GRIE--KL-LSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:PRK11650 173 MRLEiqRLhRRLKTTSLYVTHDQVEAMTLADRVVVMNGGV 212
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
49-244 5.44e-09

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 57.82  E-value: 5.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSG--KSTLLQLITGtiaPTVGTVETR------GRVAALLELGS------GFNPEF 114
Cdd:NF000106  25 EVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGRRPWRf*twcaNRRALRRTIG*hrpvr*GRRESF 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQK 194
Cdd:NF000106 102 SGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRN 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 647806363 195 RCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:NF000106 182 EVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 53-230 6.84e-09

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 56.66  E-value: 6.84e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRvaalleLGSGFNPEftgrdNVYLNA-------- 124
Cdd:PRK09544  20 LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGK------LRIGYVPQ-----KLYLDTtlpltvnr 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 125 -MLL--GMTHDEVDERFDKIAAfadiGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIE 201
Cdd:PRK09544  89 fLRLrpGTKKEDILPALKRVQA----GHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLID 164

                        170       180       190
                 ....*....|....*....|....*....|
gi 647806363 202 KLLSD-GVTLLFVSHDQESVRTLTNRAILL 230
Cdd:PRK09544 165 QLRRElDCAVLMVSHDLHLVMAKTDEVLCL 194
cbiO PRK13645
energy-coupling factor transporter ATPase;
49-245 8.66e-09

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 56.55  E-value: 8.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  49 EYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVG-TVETRGRVAALL-----------ELGSGFN-PEF- 114
Cdd:PRK13645  23 EFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGqTIVGDYAIPANLkkikevkrlrkEIGLVFQfPEYq 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 ----TGRDNVYLNAMLLGMTHDEVderFDKIAAFADI----GDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALA 186
Cdd:PRK13645 103 lfqeTIEKDIAFGPVNLGENKQEA---YKKVPELLKLvqlpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTG 179

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 187 VGDALFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK13645 180 GLDPKGEEDFINLFERLNKEyKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
52-233 9.40e-09

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 56.25  E-value: 9.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR--VAALLELGSGFN-----PEFTGRDNVYLNA 124
Cdd:PRK11248  16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKpvEGPGAERGVVFQnegllPWRNVQDNVAFGL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 125 MLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLL 204
Cdd:PRK11248  96 QLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQMQTLLLKLW 175

                        170       180       190
                 ....*....|....*....|....*....|
gi 647806363 205 SD-GVTLLFVSHDQESVRTLTNRAILLKGG 233
Cdd:PRK11248 176 QEtGKQVLLITHDIEEAVFMATELVLLSPG 205
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 53-223 1.17e-08

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 55.35  E-value: 1.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTI--APTVGTVETrgrvaalleLGSGFNPEFTGRDNVYLNamllgmt 130
Cdd:COG2401   46 LRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDV---------PDNQFGREASLIDAIGRK------- 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 131 hDEVDERFDKIAAfADIGD---YLdQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSD- 206
Cdd:COG2401  110 -GDFKDAVELLNA-VGLSDavlWL-RRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRa 186

                        170
                 ....*....|....*..
gi 647806363 207 GVTLLFVSHDQESVRTL 223
Cdd:COG2401  187 GITLVVATHHYDVIDDL 203
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 53-254 1.34e-08

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 56.98  E-value: 1.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTV---GTVETRGRVAALLELG--SG-------FNPEFTGRDNV 120
Cdd:TIGR00955  41 LKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVkgsGSVLLNGMPIDAKEMRaiSAyvqqddlFIPTLTVREHL 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  121 YLNAML-LG--MTHDEVDERFDKI--------AAFADIGDYLDqpVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGD 189
Cdd:TIGR00955 121 MFQAHLrMPrrVTKKEKRERVDEVlqalglrkCANTRIGVPGR--VKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLD 198

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363  190 ALFQKRCFGRIEKLLSDGVTLLFVSHdQESVR--TLTNRAILLKGGREVSMGSASQVLLDYRKLLHQ 254
Cdd:TIGR00955 199 SFMAYSVVQVLKGLAQKGKTIICTIH-QPSSElfELFDKIILMAEGRVAYLGSPDQAVPFFSDLGHP 264
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
52-245 1.42e-08

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 55.27  E-value: 1.42e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR------VAALLELGSGFNPE---FTGRDNVYL 122
Cdd:PRK11614  20 ALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKditdwqTAKIMREAVAIVPEgrrVFSRMTVEE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 123 NAMLLGMTHD--EVDERFDKI-AAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE-ALAVGDALFQKrCFG 198
Cdd:PRK11614 100 NLAMGGFFAErdQFQERIKWVyELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEpSLGLAPIIIQQ-IFD 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 647806363 199 RIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK11614 179 TIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALL 225
PLN03073 PLN03073
ABC transporter F family; Provisional
 54-252 1.47e-08

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 57.18  E-value: 1.47e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  54 ENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV--ETRGRVAAL-------LELGSgfNPeftgrdnvylna 124
Cdd:PLN03073 526 KNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVfrSAKVRMAVFsqhhvdgLDLSS--NP------------ 591

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 125 mLLGMTH--DEVDERfdKIAA----FADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVD-----------EALAV 187
Cdd:PLN03073 592 -LLYMMRcfPGVPEQ--KLRAhlgsFGVTGNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDepsnhldldavEALIQ 668

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 647806363 188 GDALFQkrcfgriekllsDGVtlLFVSHDQEsvrtltnraiLLKGGRE----VSMGSASQ---VLLDYRKLL 252
Cdd:PLN03073 669 GLVLFQ------------GGV--LMVSHDEH----------LISGSVDelwvVSEGKVTPfhgTFHDYKKTL 716
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 56-216 1.52e-08

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 56.73  E-value: 1.52e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  56 ISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE------TRGRVAALLELgsgFNPEFTgrdNVYLNAMLLGM 129
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILldgqpvTADNREAYRQL---FSAVFS---DFHLFDRLLGL 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 130 THDEVDERFDkiaafadigDYLDQ-------PVKT-------YSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFqKR 195
Cdd:COG4615  425 DGEADPARAR---------ELLERleldhkvSVEDgrfsttdLSQGQRKRLALLVALLEDRPILVFDEWAADQDPEF-RR 494

                        170       180
                 ....*....|....*....|....*
gi 647806363 196 CFgrIEKLLSD----GVTLLFVSHD 216
Cdd:COG4615  495 VF--YTELLPElkarGKTVIAISHD 517
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
68-244 1.54e-08

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 56.42  E-value: 1.54e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  68 IVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVaaLLELGSGFN------------------PEFTGRDNvylnaMLLGM 129
Cdd:PRK11144  29 IFGRSGAGKTSLINAISGLTRPQKGRIVLNGRV--LFDAEKGIClppekrrigyvfqdarlfPHYKVRGN-----LRYGM 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 130 THdEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDaLFQKRcfgriEKL-----L 204
Cdd:PRK11144 102 AK-SMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLD-LPRKR-----ELLpylerL 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 647806363 205 SDGVTL--LFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK11144 175 AREINIpiLYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEV 216
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 53-250 1.56e-08

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 54.46  E-value: 1.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVgtveTRGRVAallelgsgfnpeFTGRDnvylnamllgMTHD 132
Cdd:cd03217   16 LKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYEV----TEGEIL------------FKGED----------ITDL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 133 EVDER--------FDKIAAFADI--GDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE---ALAVgDALfqKRCFGR 199
Cdd:cd03217   70 PPEERarlgiflaFQYPPEIPGVknADFLRYVNEGFSGGEKKRNEILQLLLLEPDLAILDEpdsGLDI-DAL--RLVAEV 146

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 647806363 200 IEKLLSDGVTLLFVSHDQESVRTL-TNRAILLKGGREVSMGSASQVLLDYRK 250
Cdd:cd03217  147 INKLREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGDKELALEIEKK 198
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 51-94 1.74e-08

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 54.81  E-value: 1.74e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 647806363  51 WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV 94
Cdd:cd03244   18 PVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSI 61
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 52-244 1.97e-08

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 56.35  E-value: 1.97e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGT---------------IAPTVGTVET-------------------- 96
Cdd:TIGR03269  15 VLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqyeptsgriiyhvaLCEKCGYVERpskvgepcpvcggtlepeev 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   97 -------------RGRVAALLELGSGFNPEFTGRDNVyLNAM-LLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGM 162
Cdd:TIGR03269  95 dfwnlsdklrrriRKRIAIMLQRTFALYGDDTVLDNV-LEALeEIGYEGKEAVGRAVDLIEMVQLSHRITHIARDLSGGE 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  163 LVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSA 241
Cdd:TIGR03269 174 KQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKAsGISMVLTSHWPEVIEDLSDKAIWLENGEIKEEGTP 253


                  ...
gi 647806363  242 SQV 244
Cdd:TIGR03269 254 DEV 256
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 53-252 2.65e-08

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 56.27  E-value: 2.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG-------------RVAALLELGSGFNPEFtgRDN 119
Cdd:TIGR00958 497 LKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGvplvqydhhylhrQVALVGQEPVLFSGSV--REN 574

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  120 VylnamLLGMTHDEVDE-RFDKIAAFADigDYLDQPVKTY-----------SSGMLVRLAFAVQVQIDPDILIVDEALAV 187
Cdd:TIGR00958 575 I-----AYGLTDTPDEEiMAAAKAANAH--DFIMEFPNGYdtevgekgsqlSGGQKQRIAIARALVRKPRVLILDEATSA 647

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 647806363  188 GDA-----LFQKRCFGriekllsdGVTLLFVSHDQESVRTlTNRAILLKGGREVSMGSASQVLLD---YRKLL 252
Cdd:TIGR00958 648 LDAeceqlLQESRSRA--------SRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDqgcYKHLV 711
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 48-306 3.57e-08

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 56.02  E-value: 3.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  48 REYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELG-----------------SGF 110
Cdd:PRK10261 335 REVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGklqalrrdiqfifqdpyASL 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 111 NPEFTGRDNVYLNAMLLGMTHDEVDERfdKIAAFADIGDYLDQPVKTY----SSGMLVRLAFAVQVQIDPDILIVDEALA 186
Cdd:PRK10261 415 DPRQTVGDSIMEPLRVHGLLPGKAAAA--RVAWLLERVGLLPEHAWRYphefSGGQRQRICIARALALNPKVIIADEAVS 492

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 187 VGDALFQkrcfGRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSAsqvlldyRKLLHQEESDYFS 261
Cdd:PRK10261 493 ALDVSIR----GQIINLLLDlqrdfGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPR-------RAVFENPQHPYTR 561

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 647806363 262 RLMQ--PTADKAQasaSQPSDVKASSEgesaTPSNESSEKSQTPAVS 306
Cdd:PRK10261 562 KLMAavPVADPSR---QRPQRVLLSDD----LPSNIHLRGEEVAAVS 601
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 53-190 4.43e-08

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 53.27  E-value: 4.43e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV--------ETRGRVA-ALLELGSgfNPEFTGRDNVYLN 123
Cdd:cd03231   16 FSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVllnggpldFQRDSIArGLLYLGH--APGIKTTLSVLEN 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 124 AMLLGMTHDevDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:cd03231   94 LRFWHADHS--DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDK 158
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 61-216 6.36e-08

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 54.79  E-value: 6.36e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  61 RKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLEL--GSGFNPEFTG-RDN----------VYLNAMLL 127
Cdd:COG1245   97 KKGKVTGILGPNGIGKSTALKILSGELKPNLGDYDEEPSWDEVLKRfrGTELQDYFKKlANGeikvahkpqyVDLIPKVF 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 128 -GMTHD---EVDER--FDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEA---------LAVGDAlf 192
Cdd:COG1245  177 kGTVRElleKVDERgkLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPssyldiyqrLNVARL-- 254

                        170       180
                 ....*....|....*....|....
gi 647806363 193 qkrcfgrIEKLLSDGVTLLFVSHD 216
Cdd:COG1245  255 -------IRELAEEGKYVLVVEHD 271
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
52-240 9.80e-08

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 54.20  E-value: 9.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGSgfnpeftGRDN---VYLNAMLLG 128
Cdd:PRK13657 350 GVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRAS-------LRRNiavVFQDAGLFN 422

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 129 MT---------HDEVDERFDKIAAFADIGDYLDQPVKTY-----------SSGMLVRLAFAVQVQIDPDILIVDEALAVG 188
Cdd:PRK13657 423 RSiednirvgrPDATDEEMRAAAERAQAHDFIERKPDGYdtvvgergrqlSGGERQRLAIARALLKDPPILILDEATSAL 502

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 647806363 189 DALFQKRCFGRIEKlLSDGVTLLFVSHDQESVRTLTnRAILLKGGREVSMGS 240
Cdd:PRK13657 503 DVETEAKVKAALDE-LMKGRTTFIIAHRLSTVRNAD-RILVFDNGRVVESGS 552
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 59-183 1.31e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 54.02  E-value: 1.31e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  59 DIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETR---------------GRVAALLElgSGFNPEFtgrDNVYLN 123
Cdd:COG1245  362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDlkisykpqyispdydGTVEEFLR--SANTDDF---GSSYYK 436

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 124 AmllgmthdEVDERFdkiaafaDIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE 183
Cdd:COG1245  437 T--------EIIKPL-------GLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDE 481
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 52-242 1.49e-07

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 53.68  E-value: 1.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGT-----------------IAPTVGTVETRGRVAALLELgsGFNPEF 114
Cdd:TIGR02633  16 ALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVyphgtwdgeiywsgsplKASNIRDTERAGIVIIHQEL--TLVPEL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  115 TGRDNVYL-NAMLLG---MTHDEVDERFDKIAAFADIGDYLD-QPVKTYSSG--MLVRLAFAVQVQIdpDILIVDEALAV 187
Cdd:TIGR02633  94 SVAENIFLgNEITLPggrMAYNAMYLRAKNLLRELQLDADNVtRPVGDYGGGqqQLVEIAKALNKQA--RLLILDEPSSS 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 647806363  188 GDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSAS 242
Cdd:TIGR02633 172 LTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQHVATKDMS 226
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
53-244 2.12e-07

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 52.78  E-value: 2.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG----RVAAlLELGSGFNPE-------FTGRDNVY 121
Cdd:PRK10851  18 LNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGtdvsRLHA-RDRKVGFVFQhyalfrhMTVFDNIA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 LNAMLLGM----THDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCF 197
Cdd:PRK10851  97 FGLTVLPRrerpNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKELR 176

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 647806363 198 GRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK10851 177 RWLRQLHEElKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQV 224
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 52-243 2.25e-07

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 53.01  E-value: 2.25e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGT-----------------IAPTVGTVETRGRVAALLELgsGFNPEF 114
Cdd:PRK13549  20 ALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVyphgtyegeiifegeelQASNIRDTERAGIAIIHQEL--ALVKEL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYL-NAMLLG--MTHDEVDERFDKIAAFADIGDYLDQPVKTYSSG--MLVRLAFAVQVQIdpDILIVDEALAvgd 189
Cdd:PRK13549  98 SVLENIFLgNEITPGgiMDYDAMYLRAQKLLAQLKLDINPATPVGNLGLGqqQLVEIAKALNKQA--RLLILDEPTA--- 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 190 ALFQKRC---FGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQ 243
Cdd:PRK13549 173 SLTESETavlLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGRHIGTRPAAG 229
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 52-244 2.36e-07

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 53.32  E-value: 2.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVET-----RGRVAALLELG------------------- 107
Cdd:PRK10261  31 AVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCdkmllRRRSRQVIELSeqsaaqmrhvrgadmamif 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 108 ----SGFNPEFTGRDNVYLNAML-LGMTHDEVDERFDKIAAFADIGD---YLDQPVKTYSSGMLVRLAFAVQVQIDPDIL 179
Cdd:PRK10261 111 qepmTSLNPVFTVGEQIAESIRLhQGASREEAMVEAKRMLDQVRIPEaqtILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363 180 IVDEALAVGDALFQKRCFGRIEKL---LSDGVtlLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK10261 191 IADEPTTALDVTIQAQILQLIKVLqkeMSMGV--IFITHDMGVVAEIADRVLVMYQGEAVETGSVEQI 256
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 53-234 2.43e-07

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 51.32  E-value: 2.43e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLE---LGS-----GFNPEFTGR---DNV- 120
Cdd:cd03248   30 LQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEhkyLHSkvslvGQEPVLFARslqDNIa 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 YlnamllGMThDEVDERFDKIAAFADIGDYLDQPVKTY-----------SSGMLVRLAFAVQVQIDPDILIVDEALAVGD 189
Cdd:cd03248  110 Y------GLQ-SCSFECVKEAAQKAHAHSFISELASGYdtevgekgsqlSGGQKQRVAIARALIRNPQVLILDEATSALD 182

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 647806363 190 ALFQKRCfgriEKLLSDGV---TLLFVSHDQESVRTlTNRAILLKGGR 234
Cdd:cd03248  183 AESEQQV----QQALYDWPerrTVLVIAHRLSTVER-ADQILVLDGGR 225
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 52-84 2.52e-07

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 52.91  E-value: 2.52e-07
                         10        20        30
                 ....*....|....*....|....*....|...
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLIT 84
Cdd:PRK11160 355 VLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLT 387
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 24-95 2.72e-07

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 53.02  E-value: 2.72e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363   24 RDRLKQFIIPPIQRLVG--CEPSSYCREY---WALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE 95
Cdd:TIGR03719 304 RNETAEIYIPPGPRLGDkvIEAENLTKAFgdkLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIE 380
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 52-99 2.93e-07

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 51.53  E-value: 2.93e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR 99
Cdd:PRK11300  20 AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQ 67
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 52-244 3.13e-07

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 52.27  E-value: 3.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR--------VAALLE----------LGSgFNPe 113
Cdd:PRK11308  30 ALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQdllkadpeAQKLLRqkiqivfqnpYGS-LNP- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 114 ftgRDNV--YLNAMLLGMTHDEVDERFDKIAA-FADIG---DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAV 187
Cdd:PRK11308 108 ---RKKVgqILEEPLLINTSLSAAERREKALAmMAKVGlrpEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSA 184

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 647806363 188 GDALFQkrcfGRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK11308 185 LDVSVQ----AQVLNLMMDlqqelGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQI 242
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 53-258 3.29e-07

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 52.54  E-value: 3.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIaPTVGTVETRGRVAALLELGS--------GFNPEF---TGRDNVy 121
Cdd:PRK11174 366 AGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKINGIELRELDPESwrkhlswvGQNPQLphgTLRDNV- 443

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 lnamLLGmTHDEVDERFDKIAAFADIGDY-------LDQPVKTYSSGMLV----RLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:PRK11174 444 ----LLG-NPDASDEQLQQALENAWVSEFlpllpqgLDTPIGDQAAGLSVgqaqRLALARALLQPCQLLLLDEPTASLDA 518

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 647806363 191 LFQKRCFGRIEKlLSDGVTLLFVSHDQESVRTLtNRAILLKGGREVSMGSASQVLLD---YRKLLHQEESD 258
Cdd:PRK11174 519 HSEQLVMQALNA-ASRRQTTLMVTHQLEDLAQW-DQIWVMQDGQIVQQGDYAELSQAgglFATLLAHRQEE 587
PRK15177 PRK15177
Vi polysaccharide ABC transporter ATP-binding protein VexC;
53-195 3.45e-07

Vi polysaccharide ABC transporter ATP-binding protein VexC;


Pssm-ID: 185099 [Multi-domain]  Cd Length: 213  Bit Score: 50.83  E-value: 3.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGT-VETRGRvAALLELGSGFNPEFTGRDNVYLNAMLLGMTH 131
Cdd:PRK15177   3 LDKTDFVMGYHEHIGILAAPGSGKTTLTRLLCGLDAPDEGDfIGLRGD-ALPLGANSFILPGLTGEENARMMASLYGLDG 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 647806363 132 DEVDERFDKIAAFADIgdYLDQpVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKR 195
Cdd:PRK15177  82 DEFSHFCYQLTQLEQC--YTDR-VSEYSVTMKTHLAFAINLLLPCRLYIADGKLYTGDNATQLR 142
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
53-234 3.74e-07

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 51.25  E-value: 3.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLL------------QLITGTIAPTVGTVETRgrvaaLLELGSG-----FN--PE 113
Cdd:PRK09493  17 LHNIDLNIDQGEVVVIIGPSGSGKSTLLrcinkleeitsgDLIVDGLKVNDPKVDER-----LIRQEAGmvfqqFYlfPH 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 114 FTGRDNVYLNAM-LLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALF 192
Cdd:PRK09493  92 LTALENVMFGPLrVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALDPEL 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 647806363 193 QKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:PRK09493 172 RHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGR 213
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 55-240 3.76e-07

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 53.09  E-value: 3.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363    55 NISFDIRKGEAFgiVGRNGSGKSTLLQLITGTIAPTVGTVETRGR-VAALLEL---GSGFNPE-------FTGRDNVYLN 123
Cdd:TIGR01257  950 NITFYENQITAF--LGHNGAGKTTTLSILTGLLPPTSGTVLVGGKdIETNLDAvrqSLGMCPQhnilfhhLTVAEHILFY 1027

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   124 AMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFGRIEKL 203
Cdd:TIGR01257 1028 AQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKY 1107

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 647806363   204 LSdGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGS 240
Cdd:TIGR01257 1108 RS-GRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGT 1143
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 53-246 3.95e-07

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 52.31  E-value: 3.95e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLelgsgfNPEfTGRDN--VYL------NA 124
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTR------SPQ-DGLANgiVYIsedrkrDG 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 125 MLLGMT----------------------HDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVD 182
Cdd:PRK10762 341 LVLGMSvkenmsltalryfsraggslkhADEQQAVSDFIRLFNIKTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILD 420

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 183 EALAVGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGR---EVSMGSASQVLL 246
Cdd:PRK10762 421 EPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRisgEFTREQATQEKL 487
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 53-234 6.54e-07

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 51.82  E-value: 6.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV---ETrgrvAALlelgsGFNPEFTGRDnvYLNAMLLgm 129
Cdd:PRK15064 335 FKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVkwsEN----ANI-----GYYAQDHAYD--FENDLTL-- 401

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 130 thdevderFDKIAAFADIGDyLDQPVKtyssGMLVRLAF-------AVQV---------------QIDPDILIVDEALAV 187
Cdd:PRK15064 402 --------FDWMSQWRQEGD-DEQAVR----GTLGRLLFsqddikkSVKVlsggekgrmlfgklmMQKPNVLVMDEPTNH 468

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 647806363 188 GDalfqkrcFGRIEKL-----LSDGvTLLFVSHDQESVRTLTNRAILLKGGR 234
Cdd:PRK15064 469 MD-------MESIESLnmaleKYEG-TLIFVSHDREFVSSLATRIIEITPDG 512
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 52-220 7.81e-07

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 49.72  E-value: 7.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS-----GFNPE----FTG--RDNV 120
Cdd:cd03369   23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDlrsslTIIPQdptlFSGtiRSNL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 121 ylnamllgmthDEVDERFD-KIAAFADI---GDYLDQPVKtyssgMLVRLAFAVQVQidPDILIVDEALA----VGDALF 192
Cdd:cd03369  103 -----------DPFDEYSDeEIYGALRVsegGLNLSQGQR-----QLLCLARALLKR--PRVLVLDEATAsidyATDALI 164

                        170       180
                 ....*....|....*....|....*...
gi 647806363 193 QKrcfgRIEKLLSDgVTLLFVSHDQESV 220
Cdd:cd03369  165 QK----TIREEFTN-STILTIAHRLRTI 187
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
53-245 9.90e-07

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 50.17  E-value: 9.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAAllelgsGFNPEFTGRDNVYLNAMLL---GM 129
Cdd:PRK10575  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLE------SWSSKAFARKVAYLPQQLPaaeGM 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 130 THDEV-------------------DERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:PRK10575 101 TVRELvaigrypwhgalgrfgaadREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDI 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 191 LFQKRCFGRIEKLLSD-GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK10575 181 AHQVDVLALVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELM 236
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
52-183 1.44e-06

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 50.89  E-value: 1.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVET----------RGRVA---ALLELGSGFN--PEFTG 116
Cdd:NF033858  16 ALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVlggdmadarhRRAVCpriAYMPQGLGKNlyPTLSV 95

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 647806363 117 RDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGM---------LVRlafavqvqiDPDILIVDE 183
Cdd:NF033858  96 FENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMkqklglccaLIH---------DPDLLILDE 162
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 53-252 1.54e-06

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 49.53  E-value: 1.54e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTI-----APTVGTV-------------ETRGRVAALLELGSGFnPEF 114
Cdd:PRK14247  19 LDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIelypeARVSGEVyldgqdifkmdviELRRRVQMVFQIPNPI-PNL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVYLNAML--LGMTHDEVDER----FDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVG 188
Cdd:PRK14247  98 SIFENVALGLKLnrLVKSKKELQERvrwaLEKAQLWDEVKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLADEPTANL 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 189 DALFQkrcfGRIEKL---LSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLDYRKLL 252
Cdd:PRK14247 178 DPENT----AKIESLfleLKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPRHEL 240
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 53-218 1.73e-06

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 49.01  E-value: 1.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRV---------AALLELGSGFN-------PEFTG 116
Cdd:PRK10584  26 LTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPlhqmdeearAKLRAKHVGFVfqsfmliPTLNA 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 RDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDalfqKRC 196
Cdd:PRK10584 106 LENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLD----RQT 181

                        170       180
                 ....*....|....*....|....*..
gi 647806363 197 FGRIEKLL-----SDGVTLLFVSHDQE 218
Cdd:PRK10584 182 GDKIADLLfslnrEHGTTLILVTHDLQ 208
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
48-84 1.80e-06

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 50.40  E-value: 1.80e-06
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 647806363  48 REYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLIT 84
Cdd:PRK11176 354 KEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLT 390
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 45-216 2.47e-06

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 49.97  E-value: 2.47e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  45 SYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR---VAALLELGSGFNPEFTgrdNVY 121
Cdd:PRK10522 331 AYQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKpvtAEQPEDYRKLFSAVFT---DFH 407

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 LNAMLLGMTHDEVD-ERFDKIAAFADIGDYL---DQPVKT--YSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFqKR 195
Cdd:PRK10522 408 LFDQLLGPEGKPANpALVEKWLERLKMAHKLeleDGRISNlkLSKGQKKRLALLLALAEERDILLLDEWAADQDPHF-RR 486

                        170       180
                 ....*....|....*....|....*
gi 647806363 196 CFGRieKLL----SDGVTLLFVSHD 216
Cdd:PRK10522 487 EFYQ--VLLpllqEMGKTIFAISHD 509
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 61-216 3.00e-06

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 48.52  E-value: 3.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  61 RKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLElgsgfnpEFTGRD-NVYLNAML------------- 126
Cdd:cd03236   24 REGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPDWDEILD-------EFRGSElQNYFTKLLegdvkvivkpqyv 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 127 ----------LGMTHDEVDER--FDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEA---LAVGDAL 191
Cdd:cd03236   97 dlipkavkgkVGELLKKKDERgkLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPssyLDIKQRL 176

                        170       180
                 ....*....|....*....|....*
gi 647806363 192 FQKRCfgrIEKLLSDGVTLLFVSHD 216
Cdd:cd03236  177 NAARL---IRELAEDDNYVLVVEHD 198
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 53-218 4.38e-06

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 48.86  E-value: 4.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGT-----------IAPTVGTVETR-------GRVAALLELgsgfnpEF 114
Cdd:PRK10938 276 LHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDhpqgysndltlFGRRRGSGETIwdikkhiGYVSSSLHL------DY 349

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 115 TGRDNVyLNAMLLGMthdevderFDKIAAFADIGDYL------------------DQPVKTYSSGMLvRLAFAVQVQID- 175
Cdd:PRK10938 350 RVSTSV-RNVILSGF--------FDSIGIYQAVSDRQqklaqqwldilgidkrtaDAPFHSLSWGQQ-RLALIVRALVKh 419

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 647806363 176 PDILIVDEALAVGDALFQK--RCFgrIEKLLSDGVT-LLFVSHDQE 218
Cdd:PRK10938 420 PTLLILDEPLQGLDPLNRQlvRRF--VDVLISEGETqLLFVSHHAE 463
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
60-216 5.28e-06

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 49.04  E-value: 5.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  60 IRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALL------ELGSGFNPEFTGRDNV--------YLNAM 125
Cdd:PRK13409  96 PKEGKVTGILGPNGIGKTTAVKILSGELIPNLGDYEEEPSWDEVLkrfrgtELQNYFKKLYNGEIKVvhkpqyvdLIPKV 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 126 LLGMTHD---EVDER--FDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDaLFQKRCFGRI 200
Cdd:PRK13409 176 FKGKVREllkKVDERgkLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD-IRQRLNVARL 254

                        170
                 ....*....|....*.
gi 647806363 201 EKLLSDGVTLLFVSHD 216
Cdd:PRK13409 255 IRELAEGKYVLVVEHD 270
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
53-245 6.71e-06

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 47.32  E-value: 6.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRG------------RVAALL-------------EL- 106
Cdd:PRK11231  18 LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDkpismlssrqlaRRLALLpqhhltpegitvrELv 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 107 GSGFNPeftgrdnvYLNamLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALA 186
Cdd:PRK11231  98 AYGRSP--------WLS--LWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTT 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 187 VGDALFQKRCFGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVL 245
Cdd:PRK11231 168 YLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVM 226
PLN03130 PLN03130
ABC transporter C family member; Provisional
 53-301 7.41e-06

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 48.58  E-value: 7.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTV-GTVETRGRVAALLELGSGFNPefTGRDNVylnamLLGMTH 131
Cdd:PLN03130  633 LSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGELPPRSdASVVIRGTVAYVPQVSWIFNA--TVRDNI-----LFGSPF 705

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  132 DEvdERFDK---IAAFA---------DIGDYLDQPVKTySSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRCFgr 199
Cdd:PLN03130  706 DP--ERYERaidVTALQhdldllpggDLTEIGERGVNI-SGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVF-- 780

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  200 iEKLLSDGVtllfvshdQESVRTL-TNRAILLkggrevsmgsaSQVllDYRKLLHQ----EESDY---------FSRLMQ 265
Cdd:PLN03130  781 -DKCIKDEL--------RGKTRVLvTNQLHFL-----------SQV--DRIILVHEgmikEEGTYeelsnngplFQKLME 838

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 647806363  266 pTADKAQASASQPSDVKASSEGESATPSNESSEKSQ 301
Cdd:PLN03130  839 -NAGKMEEYVEENGEEEDDQTSSKPVANGNANNLKK 873
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 53-99 7.74e-06

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 47.39  E-value: 7.74e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR 99
Cdd:COG4604   17 LDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGL 63
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 53-85 9.95e-06

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 46.98  E-value: 9.95e-06
                         10        20        30
                 ....*....|....*....|....*....|...
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITG 85
Cdd:COG0396   16 LKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMG 48
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 54-95 1.06e-05

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 47.81  E-value: 1.06e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 647806363  54 ENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE 95
Cdd:PRK11819 341 DDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIK 382
ABC_sbcCD cd03279
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ...
 54-218 1.09e-05

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.


Pssm-ID: 213246 [Multi-domain]  Cd Length: 213  Bit Score: 46.49  E-value: 1.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  54 ENISF-DIRKGEAFGIVGRNGSGKSTLLQLIT----GTiAPTVGTVETRGRVAALLELGSGFNPEFTGRDNVYLNAMLLG 128
Cdd:cd03279   18 QVIDFtGLDNNGLFLICGPTGAGKSTILDAITyalyGK-TPRYGRQENLRSVFAPGEDTAEVSFTFQLGGKKYRVERSRG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 129 MTHDEvderFDKIAAFA--DIGDYLDQPVKTYSSG------MLVRLAFAVQVQ----IDPDILIVDEALAVGDALFQKRC 196
Cdd:cd03279   97 LDYDQ----FTRIVLLPqgEFDRFLARPVSTLSGGetflasLSLALALSEVLQnrggARLEALFIDEGFGTLDPEALEAV 172

                        170       180
                 ....*....|....*....|..
gi 647806363 197 FGRIEKLLSDGVTLLFVSHDQE 218
Cdd:cd03279  173 ATALELIRTENRMVGVISHVEE 194
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
53-237 1.34e-05

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 47.80  E-value: 1.34e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR---------VAALLELGSGFN-------PEFTG 116
Cdd:PRK10535  24 LKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQdvatldadaLAQLRREHFGFIfqryhllSHLTA 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 117 RDNVYLNAMLLGMTHDEVDERFDKIAAFADIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRC 196
Cdd:PRK10535 104 AQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEV 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 647806363 197 FGRIEKLLSDGVTLLFVSHDQEsVRTLTNRAILLKGGREVS 237
Cdd:PRK10535 184 MAILHQLRDRGHTVIIVTHDPQ-VAAQAERVIEIRDGEIVR 223
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 53-254 1.52e-05

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 46.38  E-value: 1.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGS-----GFNPE----FTG--RDNVy 121
Cdd:cd03249   19 LKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWlrsqiGLVSQepvlFDGtiAENI- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 lnamLLGmTHDEVDERFDKIAAFADIGDYLDQPVKTY-----------SSGMLVRLAFAVQVQIDPDILIVDEALAVGDA 190
Cdd:cd03249   98 ----RYG-KPDATDEEVEEAAKKANIHDFIMSLPDGYdtlvgergsqlSGGQKQRIAIARALLRNPKILLLDEATSALDA 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 191 LFQKRCFGRIEKLLSdGVTLLFVSHDQESVRTlTNRAILLKGGREVSMGSASQVLLD---YRKLLHQ 254
Cdd:cd03249  173 ESEKLVQEALDRAMK-GRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGTHDELMAQkgvYAKLVKA 237
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 53-85 1.57e-05

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 46.17  E-value: 1.57e-05
                         10        20        30
                 ....*....|....*....|....*....|...
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITG 85
Cdd:CHL00131  23 LKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG 55
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
52-274 1.78e-05

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 46.16  E-value: 1.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQ----LITGTIAPTV------GTVETRGRVAALLELGSG--------FN-- 111
Cdd:PRK09984  19 ALHAVDLNIHHGEMVALLGPSGSGKSTLLRhlsgLITGDKSAGShiellgRTVQREGRLARDIRKSRAntgyifqqFNlv 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 112 PEFTGRDNVYLNAmlLGMT--------HDEVDERFDKIAAFADIG--DYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIV 181
Cdd:PRK09984  99 NRLSVLENVLIGA--LGSTpfwrtcfsWFTREQKQRALQALTRVGmvHFAHQRVSTLSGGQQQRVAIARALMQQAKVILA 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 182 DEALAVGDALFQKRCFGRIEKL-LSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQvlldyrklLHQEESDYF 260
Cdd:PRK09984 177 DEPIASLDPESARIVMDTLRDInQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQ--------FDNERFDHL 248

                        250
                 ....*....|....
gi 647806363 261 SRLMQPTADKAQAS 274
Cdd:PRK09984 249 YRSINRVEENAKAA 262
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 52-244 2.10e-05

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 46.27  E-value: 2.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIaptvgtvETRGRVAALlelgsgfNPEFTGRDNVYLN-------- 123
Cdd:PRK11022  22 AVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLI-------DYPGRVMAE-------KLEFNGQDLQRISekerrnlv 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 124 ----AMLL-------------------------GMTHDEVDERFDKIAAFADIGD---YLDQPVKTYSSGMLVRLAFAVQ 171
Cdd:PRK11022  88 gaevAMIFqdpmtslnpcytvgfqimeaikvhqGGNKKTRRQRAIDLLNQVGIPDpasRLDVYPHQLSGGMSQRVMIAMA 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 172 VQIDPDILIVDEALAVGDALFQKRCfgrIEKLLS----DGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK11022 168 IACRPKLLIADEPTTALDVTIQAQI---IELLLElqqkENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDI 241
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 52-247 2.62e-05

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 46.65  E-value: 2.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAAL------LELG-SGFNPEF------TGRD 118
Cdd:PRK10982  13 ALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFksskeaLENGiSMVHQELnlvlqrSVMD 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 NVYLNAM-LLGMTHDEVDERFDKIAAFADIGDYLDQPVK--TYSSGMLVRLAFAVQVQIDPDILIVDEALAvgdALFQKR 195
Cdd:PRK10982  93 NMWLGRYpTKGMFVDQDKMYRDTKAIFDELDIDIDPRAKvaTLSVSQMQMIEIAKAFSYNAKIVIMDEPTS---SLTEKE 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 647806363 196 C---FGRIEKLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQVLLD 247
Cdd:PRK10982 170 VnhlFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLAGLTMD 224
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
52-189 2.87e-05

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 46.63  E-value: 2.87e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLI-------TGTIA------PTVGTVETRGRVAALlelgsGFNPeFTGRD 118
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIqrhfdvsEGDIRfhdiplTKLQLDSWRSRLAVV-----SQTP-FLFSD 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 119 NVYLNaMLLGMThDEVDERFDKIAAFADIGD---YLDQPVKT--------YSSGMLVRLAFAVQVQIDPDILIVDEALAV 187
Cdd:PRK10789 404 TVANN-IALGRP-DATQQEIEHVARLASVHDdilRLPQGYDTevgergvmLSGGQKQRISIARALLLNAEILILDDALSA 481


                 ..
gi 647806363 188 GD 189
Cdd:PRK10789 482 VD 483
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 52-100 4.39e-05

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 45.03  E-value: 4.39e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLL-------QLI-----TGTI--------APTVGTVETRGRV 100
Cdd:COG1117   26 ALKDINLDIPENKVTALIGPSGCGKSTLLrclnrmnDLIpgarvEGEIlldgediyDPDVDVVELRRRV 94
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
56-186 4.40e-05

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 44.45  E-value: 4.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  56 ISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVET---------RGRVAALLELGSGFNPEFTGRDNV-YLNAM 125
Cdd:PRK13543  30 LDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIdgktatrgdRSRFMAYLGHLPGLKADLSTLENLhFLCGL 109

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 647806363 126 llgmtHDEVDERFDKIA-AFADIGDYLDQPVKTYSSGMLVRLAFAvQVQIDPDIL-IVDEALA 186
Cdd:PRK13543 110 -----HGRRAKQMPGSAlAIVGLAGYEDTLVRQLSAGQKKRLALA-RLWLSPAPLwLLDEPYA 166
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 52-244 4.49e-05

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 45.49  E-value: 4.49e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTvgtvetrGRVAallelGSGfnpEFTGRDNVYLN-------- 123
Cdd:PRK09473  31 AVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAAN-------GRIG-----GSA---TFNGREILNLPekelnklr 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 124 ----AMLLG--MTH--------DEVDE------RFDKIAAFADIGDYLDQpVKT-------------YSSGMLVRLAFAV 170
Cdd:PRK09473  96 aeqiSMIFQdpMTSlnpymrvgEQLMEvlmlhkGMSKAEAFEESVRMLDA-VKMpearkrmkmypheFSGGMRQRVMIAM 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 647806363 171 QVQIDPDILIVDEALAVGDALFQkrcfGRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQV 244
Cdd:PRK09473 175 ALLCRPKLLIADEPTTALDVTVQ----AQIMTLLNElkrefNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDV 249
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 53-153 5.38e-05

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 45.70  E-value: 5.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363   53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGtvETR---GRVAALLELGSGFNPEFTGRDNVylnamLLGM 129
Cdd:TIGR03719  21 LKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNG--EARpqpGIKVGYLPQEPQLDPTKTVRENV-----EEGV 93

                          90       100
                  ....*....|....*....|....*..
gi 647806363  130 tHDEVD--ERFDKI-AAFADIGDYLDQ 153
Cdd:TIGR03719  94 -AEIKDalDRFNEIsAKYAEPDADFDK 119
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 53-243 8.97e-05

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 44.80  E-value: 8.97e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGtIAP-TVGTVE--TRGRVAAL-----LELGsgfnpefTGRDNVYLNA 124
Cdd:COG4178  379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIAG-LWPyGSGRIArpAGARVLFLpqrpyLPLG-------TLREALLYPA 450

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 125 MLLGMTHDEVDERFDKiAAFADIGDYLDQPV---KTYSSGMLVRLAFA-VQVQiDPDILIVDEALAVGDALFQKRCFGRI 200
Cdd:COG4178  451 TAEAFSDAELREALEA-VGLGHLAERLDEEAdwdQVLSLGEQQRLAFArLLLH-KPDWLFLDEATSALDEENEAALYQLL 528

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 647806363 201 EKLLSDgVTLLFVSHdQESVRTLTNRAILLKGGREVSMGSASQ 243
Cdd:COG4178  529 REELPG-TTVISVGH-RSTLAAFHDRVLELTGDGSWQLLPAEA 569
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 54-94 9.67e-05

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 44.88  E-value: 9.67e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 647806363  54 ENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV 94
Cdd:PRK15064  18 ENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNV 58
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 53-120 9.88e-05

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 44.94  E-value: 9.88e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE--TRGRVAALLELGSGFNPEFTGRDNV 120
Cdd:PRK11147 335 VKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHcgTKLEVAYFDQHRAELDPEKTVMDNL 404
GguA NF040905
sugar ABC transporter ATP-binding protein;
52-85 1.05e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 44.78  E-value: 1.05e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITG 85
Cdd:NF040905  16 ALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG 49
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 53-80 1.10e-04

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 44.07  E-value: 1.10e-04
                         10        20
                 ....*....|....*....|....*...
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLL 80
Cdd:cd03289   20 LENISFSISPGQRVGLLGRTGSGKSTLL 47
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
54-99 2.42e-04

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 43.36  E-value: 2.42e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 647806363  54 ENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR 99
Cdd:PRK11288 270 EPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGK 315
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 68-221 2.50e-04

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 42.21  E-value: 2.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  68 IVGRNGSGKSTLLQLI----TGTIAPT----------VGTVETRGRVAALLELGSGFNPEFTGRDNVYLNAMllgMTHDE 133
Cdd:cd03240   27 IVGQNGAGKTTIIEALkyalTGELPPNskggahdpklIREGEVRAQVKLAFENANGKKYTITRSLAILENVI---FCHQG 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 134 vderfdkiaafaDIGDYLDQPVKTYSSG------MLVRLAFAVQVQIDPDILIVDEALAVGDAlfqkrcfGRIEKLLSDG 207
Cdd:cd03240  104 ------------ESNWPLLDMRGRCSGGekvlasLIIRLALAETFGSNCGILALDEPTTNLDE-------ENIEESLAEI 164

                        170       180
                 ....*....|....*....|...
gi 647806363 208 VT---------LLFVSHDQESVR 221
Cdd:cd03240  165 IEerksqknfqLIVITHDEELVD 187
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 53-239 3.38e-04

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 41.77  E-value: 3.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITG-TIAPTV-GTVETRGRVAALLELG--SGF-------NPEFTGRDNVY 121
Cdd:cd03213   25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrRTGLGVsGEVLINGRPLDKRSFRkiIGYvpqddilHPTLTVRETLM 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 LNAMLLGMthdevderfdkiaafadigdyldqpvktySSGMLVRLAFAVQVQIDPDILIVDEA---LAVGDALFQKRCfg 198
Cdd:cd03213  105 FAAKLRGL-----------------------------SGGERKRVSIALELVSNPSLLFLDEPtsgLDSSSALQVMSL-- 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 647806363 199 rIEKLLSDGVTLLFVSHD-QESVRTLTNRAILLKGGREVSMG 239
Cdd:cd03213  154 -LRRLADTGRTIICSIHQpSSEIFELFDKLLLLSQGRVIYFG 194
PTZ00243 PTZ00243
ABC transporter; Provisional
 53-80 3.51e-04

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 43.23  E-value: 3.51e-04
                          10        20
                  ....*....|....*....|....*...
gi 647806363   53 LENISFDIRKGEAFGIVGRNGSGKSTLL 80
Cdd:PTZ00243 1326 LRGVSFRIAPREKVGIVGRTGSGKSTLL 1353
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 53-237 3.75e-04

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 43.02  E-value: 3.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV--ETRGRVAALL------ELGSGFN--PEFTGRDNVYL 122
Cdd:PRK11147  19 LDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIiyEQDLIVARLQqdpprnVEGTVYDfvAEGIEEQAEYL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 123 ---NAMLLGMTHDEVDERFDKIAAFADIGDYL--------------------DQPVKTYSSGMLVRLAFAVQVQIDPDIL 179
Cdd:PRK11147  99 kryHDISHLVETDPSEKNLNELAKLQEQLDHHnlwqlenrinevlaqlgldpDAALSSLSGGWLRKAALGRALVSNPDVL 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 647806363 180 IVDEA---LAVgDALFQKRCFgriekLLSDGVTLLFVSHDQESVRTLTNRAILLKGGREVS 237
Cdd:PRK11147 179 LLDEPtnhLDI-ETIEWLEGF-----LKTFQGSIIFISHDRSFIRNMATRIVDLDRGKLVS 233
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
66-216 4.22e-04

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 41.53  E-value: 4.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  66 FGIVGRNGSGKSTLLQLIT-------GTIAPTVGTVETRGRVAALLELgsgfnpEFTGRDNVY----------------- 121
Cdd:COG0419   26 NLIVGPNGAGKSTILEAIRyalygkaRSRSKLRSDLINVGSEEASVEL------EFEHGGKRYrierrqgefaefleakp 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 122 ------LNAMLLGMTHDEVDERFDKIAA-------------------FADIGDYldQPVKTYSSGMLVRLAFAVQVQIDP 176
Cdd:COG0419  100 serkeaLKRLLGLEIYEELKERLKELEEalesaleelaelqklkqeiLAQLSGL--DPIETLSGGERLRLALADLLSLIL 177

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 647806363 177 DILIVDEalavgdalfqkrcfGRIEKLLSDGVTLLFVSHD 216
Cdd:COG0419  178 DFGSLDE--------------ERLERLLDALEELAIITHV 203
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 52-183 4.39e-04

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 41.40  E-value: 4.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFG------------IVGRNGSGKSTLLQLITGTIAPTVGTVETR----GRVAALLELGSGFNPEFT 115
Cdd:PRK13541   3 SLHQLQFNIEQKNLFDlsitflpsaityIKGANGCGKSSLLRMIAGIMQPSSGNIYYKncniNNIAKPYCTYIGHNLGLK 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 647806363 116 GRDNVYLNAMLLGMTHDEVDERFDKIAAFAdIGDYLDQPVKTYSSGMLVRLAFAVQVQIDPDILIVDE 183
Cdd:PRK13541  83 LEMTVFENLKFWSEIYNSAETLYAAIHYFK-LHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDE 149
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 53-80 4.97e-04

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 42.98  E-value: 4.97e-04
                           10        20
                   ....*....|....*....|....*...
gi 647806363    53 LENISFDIRKGEAFGIVGRNGSGKSTLL 80
Cdd:TIGR01271 1235 LQDLSFSVEGGQRVGLLGRTGSGKSTLL 1262
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
45-186 5.07e-04

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 42.40  E-value: 5.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  45 SYCREYWALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGRVAALLELGsgfnpefTGRDNVylnA 124
Cdd:PRK10790 349 AYRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHS-------VLRQGV---A 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 125 MLlgmTHDEV---DERFDKIAAFADIGD----------YLDQPVKTYSSGMLVR---------------LAFA-VQVQId 175
Cdd:PRK10790 419 MV---QQDPVvlaDTFLANVTLGRDISEeqvwqaletvQLAELARSLPDGLYTPlgeqgnnlsvgqkqlLALArVLVQT- 494

                        170
                 ....*....|.
gi 647806363 176 PDILIVDEALA 186
Cdd:PRK10790 495 PQILILDEATA 505
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 53-94 5.46e-04

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 42.46  E-value: 5.46e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV 94
Cdd:PRK10636  17 LDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSY 58
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 54-278 5.89e-04

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 42.38  E-value: 5.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  54 ENISFDIRKGEAFGIVGRNGSGKS----TLLQLI--------TGTI-----------APTVGTVetRGRVAALL--ELGS 108
Cdd:PRK15134  26 NDVSLQIEAGETLALVGESGSGKSvtalSILRLLpsppvvypSGDIrfhgesllhasEQTLRGV--RGNKIAMIfqEPMV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 109 GFNPEFTGRDNVY-LNAMLLGMTHDevderfdkiAAFADIGDYLD-----QPVK-------TYSSGMLVRLAFAVQVQID 175
Cdd:PRK15134 104 SLNPLHTLEKQLYeVLSLHRGMRRE---------AARGEILNCLDrvgirQAAKrltdyphQLSGGERQRVMIAMALLTR 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 176 PDILIVDEALAVGDALFQkrcfGRIEKLLSD-----GVTLLFVSHDQESVRTLTNRAILLKGGREVSMGSASQvlldyrk 250
Cdd:PRK15134 175 PELLIADEPTTALDVSVQ----AQILQLLRElqqelNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAAT------- 243

                        250       260       270
                 ....*....|....*....|....*....|
gi 647806363 251 LLHQEESDYFSRLM--QPTADKAQASASQP 278
Cdd:PRK15134 244 LFSAPTHPYTQKLLnsEPSGDPVPLPEPAS 273
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 59-95 6.31e-04

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 40.63  E-value: 6.31e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 647806363  59 DIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVE 95
Cdd:cd03222   21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDE 57
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
 52-184 7.62e-04

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 41.31  E-value: 7.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  52 ALENISFDIRKGEAFG-IVGRNGSGKSTLLQLITGTIAPTVgtvetrgRVAALlelgsgFNPEFTGRDnvylnamLLGMT 130
Cdd:COG3267   31 ALARLEYALAQGGGFVvLTGEVGTGKTTLLRRLLERLPDDV-------KVAYI------PNPQLSPAE-------LLRAI 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 647806363 131 HDEVD---ERFDKIAAFADIGDYLdqpVKTYSSGMLVrlafavqvqidpdILIVDEA 184
Cdd:COG3267   91 ADELGlepKGASKADLLRQLQEFL---LELAAAGRRV-------------VLIIDEA 131
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 53-94 8.35e-04

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 41.73  E-value: 8.35e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTV 94
Cdd:COG5265  374 LKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRI 415
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 53-152 1.10e-03

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 41.26  E-value: 1.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITG---------TIAP--TVGtvetrgrvaaLLELGSGFNPEFTGRDNVy 121
Cdd:PRK11819  23 LKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGvdkefegeaRPAPgiKVG----------YLPQEPQLDPEKTVRENV- 91

                         90       100       110
                 ....*....|....*....|....*....|..
gi 647806363 122 lnAMLLGMTHDEVDeRFDKI-AAFADIGDYLD 152
Cdd:PRK11819  92 --EEGVAEVKAALD-RFNEIyAAYAEPDADFD 120
AAA_23 pfam13476
AAA domain;
53-84 1.44e-03

AAA domain;


Pssm-ID: 463890 [Multi-domain]  Cd Length: 190  Bit Score: 39.79  E-value: 1.44e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 647806363   53 LENISFDIRKGeAFGIVGRNGSGKSTLLQLIT 84
Cdd:pfam13476   9 FRDQTIDFSKG-LTLITGPNGSGKTTILDAIK 39
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 52-99 1.73e-03

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 40.76  E-value: 1.73e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 647806363  52 ALENISFDIRKGEAFGIVGRNGSGKSTLLQLITGTIAPTVGTVETRGR 99
Cdd:PRK10762  19 ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGK 66
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 53-85 1.80e-03

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 39.06  E-value: 1.80e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 647806363  53 LENISFDIRKGEAFGIVGRNGSGKSTLLQLITG 85
Cdd:cd03223   17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAG 49
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 137-274 2.32e-03

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 39.69  E-value: 2.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647806363 137 RFDKIAAFADIGDYL-DQPVKtYSSGMLVRLAFAVQVQIDPDILIVDEALAVGDALFQKRcfgrIEKL---LSDGVTLLF 212
Cdd:PRK14271 143 RLTEVGLWDAVKDRLsDSPFR-LSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEK----IEEFirsLADRLTVII 217

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 647806363 213 VSHDQESVRTLTNRAILLKGGREVSMGSASQVLLDYRkllHQEESDYFSRLMQPTADKAQAS 274
Cdd:PRK14271 218 VTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPK---HAETARYVAGLSGDVKDAKRGN 276
COG3950 COG3950
Predicted ATP-binding protein involved in virulence [General function prediction only];
53-83 5.83e-03

Predicted ATP-binding protein involved in virulence [General function prediction only];


Pssm-ID: 443150 [Multi-domain]  Cd Length: 276  Bit Score: 38.44  E-value: 5.83e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 647806363  53 LENISFDIRKGEAFG-IVGRNGSGKSTLLQLI 83
Cdd:COG3950   14 FEDLEIDFDNPPRLTvLVGENGSGKTTLLEAI 45
PLN03130 PLN03130
ABC transporter C family member; Provisional
 53-80 7.85e-03

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 38.95  E-value: 7.85e-03
                          10        20
                  ....*....|....*....|....*...
gi 647806363   53 LENISFDIRKGEAFGIVGRNGSGKSTLL 80
Cdd:PLN03130 1255 LHGLSFEISPSEKVGIVGRTGAGKSSML 1282
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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