NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|639961142|ref|WP_024768050|]
View 

MULTISPECIES: helix-turn-helix transcriptional regulator [Brucella]

Protein Classification

helix-turn-helix transcriptional regulator( domain architecture ID 12204063)

helix-turn-helix (HTH) transcriptional regulator containing an AraC family DNA-binding HTH domain controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence

CATH:  1.10.10.1310
Gene Ontology:  GO:0006355|GO:0043565|GO:0003700
PubMed:  2644244|15808743|8831795
SCOP:  4000332

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
171-254 1.78e-24

helix_turn_helix, arabinose operon control protein;


:

Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 93.39  E-value: 1.78e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142   171 DLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTFTSAFRKLYGFSP 250
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 639961142   251 KKMR 254
Cdd:smart00342  81 SEYR 84
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
171-254 1.78e-24

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 93.39  E-value: 1.78e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142   171 DLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTFTSAFRKLYGFSP 250
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 639961142   251 KKMR 254
Cdd:smart00342  81 SEYR 84
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 159-255 2.35e-22

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 93.68  E-value: 2.35e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 159 RIREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTF 238
Cdd:COG4977  214 RAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASHF 293

                         90
                 ....*....|....*..
gi 639961142 239 TSAFRKLYGFSPKKMRA 255
Cdd:COG4977  294 RRAFRRRFGVSPSAYRR 310
HTH_18 pfam12833
Helix-turn-helix domain;
177-255 4.83e-19

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 79.17  E-value: 4.83e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142  177 IAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDS-IPISQAAHLAGYNNTSTFTSAFRKLYGFSPKKMRA 255
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEDTgLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80
ftrA PRK09393
transcriptional activator FtrA; Provisional
 147-255 4.70e-12

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 64.99  E-value: 4.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 147 PVlSSANRQDCERIREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQA 226
Cdd:PRK09393 211 PV-ASRESDRLGPLIDWMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLESSALSIDQI 289

                         90       100
                 ....*....|....*....|....*....
gi 639961142 227 AHLAGYNNTSTFTSAFRKLYGFSPKKMRA 255
Cdd:PRK09393 290 AERAGFGSEESLRHHFRRRAATSPAAYRK 318
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
171-254 1.78e-24

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 93.39  E-value: 1.78e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142   171 DLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTFTSAFRKLYGFSP 250
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 639961142   251 KKMR 254
Cdd:smart00342  81 SEYR 84
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 159-255 2.35e-22

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 93.68  E-value: 2.35e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 159 RIREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTF 238
Cdd:COG4977  214 RAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASHF 293

                         90
                 ....*....|....*..
gi 639961142 239 TSAFRKLYGFSPKKMRA 255
Cdd:COG4977  294 RRAFRRRFGVSPSAYRR 310
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
158-261 4.62e-22

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.15  E-value: 4.62e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 158 ERIREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTST 237
Cdd:COG2207  155 LLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSH 234

                         90       100
                 ....*....|....*....|....
gi 639961142 238 FTSAFRKLYGFSPKKMRALGKGDP 261
Cdd:COG2207  235 FSRAFKKRFGVTPSEYRKRLRARA 258
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 158-259 3.04e-19

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 85.88  E-value: 3.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 158 ERIREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSiPISQAAHLAGYNNTST 237
Cdd:COG2169   87 ARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRARQLLQTGL-SVTDAAYAAGFGSLSR 165

                         90       100
                 ....*....|....*....|..
gi 639961142 238 FTSAFRKLYGFSPKKMRALGKG 259
Cdd:COG2169  166 FYEAFKKLLGMTPSAYRRGGAG 187
HTH_18 pfam12833
Helix-turn-helix domain;
177-255 4.83e-19

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 79.17  E-value: 4.83e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142  177 IAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDS-IPISQAAHLAGYNNTSTFTSAFRKLYGFSPKKMRA 255
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEDTgLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80
ftrA PRK09393
transcriptional activator FtrA; Provisional
 147-255 4.70e-12

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 64.99  E-value: 4.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 147 PVlSSANRQDCERIREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQA 226
Cdd:PRK09393 211 PV-ASRESDRLGPLIDWMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLESSALSIDQI 289

                         90       100
                 ....*....|....*....|....*....
gi 639961142 227 AHLAGYNNTSTFTSAFRKLYGFSPKKMRA 255
Cdd:PRK09393 290 AERAGFGSEESLRHHFRRRAATSPAAYRK 318
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
159-255 4.36e-11

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 61.91  E-value: 4.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 159 RIRE---FIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNT 235
Cdd:PRK10572 184 RVREacqYISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQ 263

                         90       100
                 ....*....|....*....|
gi 639961142 236 STFTSAFRKLYGFSPKKMRA 255
Cdd:PRK10572 264 LYFSRVFKKCTGASPSEFRA 283
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
162-254 5.03e-11

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 58.40  E-value: 5.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 162 EFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTFTSA 241
Cdd:PRK10219  12 AWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRV 91

                         90
                 ....*....|...
gi 639961142 242 FRKLYGFSPKKMR 254
Cdd:PRK10219  92 FRRQFDRTPSDYR 104
PRK11511 PRK11511
MDR efflux pump AcrAB transcriptional activator MarA;
160-254 1.21e-07

MDR efflux pump AcrAB transcriptional activator MarA;


Pssm-ID: 236920 [Multi-domain]  Cd Length: 127  Bit Score: 49.33  E-value: 1.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 160 IREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTFT 239
Cdd:PRK11511  14 ILDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLT 93

                         90
                 ....*....|....*
gi 639961142 240 SAFRKLYGFSPKKMR 254
Cdd:PRK11511  94 RTFKNYFDVPPHKYR 108
PRK10371 PRK10371
transcriptional regulator MelR;
162-259 1.77e-07

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 51.36  E-value: 1.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 162 EFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTFTSA 241
Cdd:PRK10371 198 GFIAENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYST 277

                         90
                 ....*....|....*...
gi 639961142 242 FRKLYGFSPKKMRALGKG 259
Cdd:PRK10371 278 FGKYVGMSPQQYRKLSQQ 295
PRK15121 PRK15121
MDR efflux pump AcrAB transcriptional activator RobA;
167-250 1.17e-06

MDR efflux pump AcrAB transcriptional activator RobA;


Pssm-ID: 185076 [Multi-domain]  Cd Length: 289  Bit Score: 48.85  E-value: 1.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 167 NLDRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTFTSAFRKLY 246
Cdd:PRK15121  17 HLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKAAVALRLTSRPILDIALQYRFDSQQTFTRAFKKQF 96


                 ....
gi 639961142 247 GFSP 250
Cdd:PRK15121  97 AQTP 100
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
98-254 1.55e-06

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 48.13  E-value: 1.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142  98 QHILQLAEKI------MNPPSVAAGPLatlyLRVQGLDIMWQACLAmmaekekqppvlSSANRQDcERIREFI---MANL 168
Cdd:PRK13503 122 QQVRQLVAQMeqqeesNDLEAIASREI----LFMQLLVLLRKSSLQ------------ENGENSD-ARLNQLLawlEDHF 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 169 DRDLTIDLIAQKVAISASTVQRRFKKHYGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTFTSAFRKLYGF 248
Cdd:PRK13503 185 AEEVNWEALADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLLKARHLLRHSDASVTDIAYRCGFGDSNHFSTLFRREFSW 264


                 ....*.
gi 639961142 249 SPKKMR 254
Cdd:PRK13503 265 SPRDIR 270
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 158-256 1.00e-05

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 45.83  E-value: 1.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 158 ERIREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYgTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTST 237
Cdd:PRK15186 184 ENIYNIIISDISRKWALKDISDSLYMSCSTLKRKLKQEN-TSFSEVYLNARMNKATKLLRNSEYNITRVAYMCGYDSASY 262

                         90
                 ....*....|....*....
gi 639961142 238 FTSAFRKLYGFSPKKMRAL 256
Cdd:PRK15186 263 FTCVFKKHFKTTPSEFLAF 281
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 159-250 1.25e-05

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 45.69  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 159 RIREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHyGTTLYNFIKQQRLEAACVALSRDSIPISQAAHLAGYNNTSTF 238
Cdd:PRK09978 146 RVCTVINNNIAHEWTLARIASELLMSPSLLKKKLREE-ETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGYHSVSYF 224

                         90
                 ....*....|..
gi 639961142 239 TSAFRKLYGFSP 250
Cdd:PRK09978 225 IYVFRNYYGMTP 236
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 148-250 1.85e-05

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 44.99  E-value: 1.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 148 VLSSANRQDCERIREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHyGTTLYNFIKQQRLEAACVALSRDSIPISQAA 227
Cdd:PRK15185 199 ILSSAQITLKERVYNIISSSPSRQWKLTDVADHIFMSTSTLKRKLAEE-GTSFSDIYLSARMNQAAKLLRIGNHNVNAVA 277

                         90       100
                 ....*....|....*....|...
gi 639961142 228 HLAGYNNTSTFTSAFRKLYGFSP 250
Cdd:PRK15185 278 LKCGYDSTSYFIQCFKKYFKTTP 300
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 159-255 1.94e-04

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 41.94  E-value: 1.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 159 RIREFIMANLDRD-LTIDLIAQKVAISASTVQRRFKKHyGTTLYNFIKQQRLEAACVALSRDSI--PISQAAHLAGYNNT 235
Cdd:PRK09685 201 KVVALIDQSIQEEiLRPEWIAGELGISVRSLYRLFAEQ-GLVVAQYIRNRRLDRCADDLRPAADdeKITSIAYKWGFSDS 279

                         90       100
                 ....*....|....*....|
gi 639961142 236 STFTSAFRKLYGFSPKKMRA 255
Cdd:PRK09685 280 SHFSTAFKQRFGVSPGEYRR 299
PRK09940 PRK09940
transcriptional regulator YdeO; Provisional
 129-267 7.38e-04

transcriptional regulator YdeO; Provisional


Pssm-ID: 182157 [Multi-domain]  Cd Length: 253  Bit Score: 40.07  E-value: 7.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639961142 129 DIMWQACLAMMAEKEKQPPVLSSANRQDCERIREFIMANLDRDLTIDLIAQKVAISASTVQRRFKKHYgTTLYNFIKQQR 208
Cdd:PRK09940 108 ELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCLYISESLLKKKLKQEQ-TTFSQILLDAR 186

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 639961142 209 LEAAcVALSRDSIPISQAAHLAGYNNTSTFTSAFRKLYGFSPKKmraLGKGDPCRSGSG 267
Cdd:PRK09940 187 MQHA-KNLIRVEGSVNKIAEQCGYASTSYFIYAFRKHFGNSPKR---VSKEYRCQRHTG 241
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 167-199 1.55e-03

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 35.59  E-value: 1.55e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 639961142  167 NLDRDLTIDLIAQKVAISASTVQRRFKKHYGTT 199
Cdd:pfam00165   4 NLSTNLTIADIADELGFSRSYFSRLFKKYTGVT 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH