|
Name |
Accession |
Description |
Interval |
E-value |
| PBP1_RPA0985_benzoate-like |
cd20013 |
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the ... |
33-384 |
0e+00 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0985 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0985 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380666 [Multi-domain] Cd Length: 356 Bit Score: 531.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDTIAGKKIEVILKDDAAL-PDKTKTAAQELIVSEKVNAIAGFGVTPAAL 111
Cdd:cd20013 1 KVGVIGPFSGPFADYGKQFDRGIDLYLKLHGDKVGGRKVEVIYRDDGGPnPAVAKRLAQELIVRDKVQILIGFGFTPNAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 112 AAAPLATQGKIPEIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEHFAAG 191
Cdd:cd20013 81 AVAPVATEAKTPTVIMNAATSSITRKSPYFVRTSFTMWQVAYPMGKWAAKNGIKKAYTAVADYAPGHDAETAFKKAFEAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 192 GGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAG-QGGNFMKQYAERGLDKAGIKVIGPGDVMDDDLLNGMGDAA 270
Cdd:cd20013 161 GGKIVGSIRVPLATPDFAPFMQRIKDAKPDAVFVFVPAGaPSIGFLKAYAERGLKEAGIKLLGTGDATDDDDLPAMGDAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 271 LGAVTAHIYSAAHPSQANKDFVAAYKKAFGN--RPGFMAVGGYDGIHLIYEALKKTGGKTDGDALVAAMKGMKWESPRGP 348
Cdd:cd20013 241 LGLITAGHYSAALDSPENKAFVAAYQKAYGPdaRPDFMAVAAYDGMALIYKMIKATGGKFDGDKAMAAVKGLKWESPRGP 320
|
330 340 350
....*....|....*....|....*....|....*.
gi 639173078 349 ISIDPDTRDIVQNVYIRKVGKVDGELYNVEFETFEA 384
Cdd:cd20013 321 ISIDPETRDIVQNVYIRRVEKVDGKLQNVEFDTFEA 356
|
|
| PBP1_aromatic_compounds-like |
cd06332 |
type 1 periplasmic binding proteins of active transport systems predicted to be involved in ... |
33-367 |
1.47e-115 |
|
type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.
Pssm-ID: 380555 [Multi-domain] Cd Length: 336 Bit Score: 339.96 E-value: 1.47e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAALA 112
Cdd:cd06332 1 KIGLLAPLTGPFAALGEDMVRGFELALEEVGGEVAGRKVELVVEDDAGDPDTAVTKARKLVEQDKVDVLIGPLSGDEGLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 113 AAPLATQGKIPEIVMAAGTSIITE--KSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLTSDYAPGNDALTSFKEHFA 189
Cdd:cd06332 81 VAPYAKEPGVPFINPVAGADDLTQraKAPNFFRTSFTGSQWSAPLGDYAYKElGYKKVATIGSDYAFGYEQAAGFKRGFE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 190 AGGGEIVEEVKVPLANPDFAPFLQRMKDAKpDAMFVFVPAGQGGNFMKQYAERGLDKaGIKVIGPGDVMDDDLLNGMGDA 269
Cdd:cd06332 161 AAGGEVVQEIWVPLGTTDFSPYIAQIPSAD-DAVFAFLGGADAVRFLKQYREFGLKD-KIPLIGGGTTVDESVLPAMGDA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 270 ALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKT-DGDALVAAMKGMKWESPRGP 348
Cdd:cd06332 239 ALGIISASHYAEGLDNPENKKFVAAYKKKFGKLPSLYAAGGYDGAQAILEALEAVGGDVsDKQALAAALRKVKFDSPRGP 318
|
330
....*....|....*....
gi 639173078 349 ISIDPDtRDIVQNVYIRKV 367
Cdd:cd06332 319 FSFDEN-RNPVQNVYIREV 336
|
|
| PBP1_RPA0668_benzoate-like |
cd20014 |
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the ... |
33-374 |
1.31e-100 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380667 [Multi-domain] Cd Length: 346 Bit Score: 302.23 E-value: 1.31e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAALA 112
Cdd:cd20014 1 KIGLLLPYSGVYAALGEDIRNGFQLYLDEHGGKLGGRPIELVKEDDEADPDVALQKARKLIEQDKVDVLVGPVSSGVALA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 113 AAPLATQGKIPEIVMAAGTSIIT--EKSPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEHFAA 190
Cdd:cd20014 81 IRDVVEQAKVPLIVANAGANALTraACSPYIFRTSFSNWQLGYALGKYAAENVGKTVVTIASDYAAGREVVAGFKEGFEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 191 GGGEIVEEVKVPL-ANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLdKAGIKVIGPGDVMDDDLLNGMGDA 269
Cdd:cd20014 161 AGGKVVGEIWTPLgTTTDFSPYLTQIAASGPDAVYAFFAGADAVRFVKQYAEFGL-KGKIPLYGPGFLTDEDVLPALGEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 270 ALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKT-DGDALVAAMKGMKWESPRGP 348
Cdd:cd20014 240 AEGIITVLHYAPTLDNPANRAFVAAYQAKYGRLPDVYAVQGYDAAQVIDAALEAVGGDTsDKDILAAALELGSIDSPRGP 319
|
330 340
....*....|....*....|....*.
gi 639173078 349 ISIDPDTRDIVQNVYIRKVGKVDGEL 374
Cdd:cd20014 320 FRFDPTTHNPIQNIYLREVVKGGGGL 345
|
|
| PBP1_alkylbenzenes-like |
cd06360 |
type 1 periplasmic binding component of active transport systems predicted be involved in ... |
33-387 |
1.09e-93 |
|
type 1 periplasmic binding component of active transport systems predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; This group includes the type 1 periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.
Pssm-ID: 380583 [Multi-domain] Cd Length: 357 Bit Score: 284.96 E-value: 1.09e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAALA 112
Cdd:cd06360 1 KIGVLLPLTGPLAVNGEDVRDGFELYFDEIGNQVAGRKIELIVEDDEGKPDVGLTKARKLVERDKVHVLAGIVSSAVAYA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 113 AAPLATQGKIPEIVMAAGTSIITEK--SPYIVRTSFTLPQSSTIIGDWAV-KNGIKKVATLTSDYAPGNDALTSFKEHFA 189
Cdd:cd06360 81 VRDYVVEQKIPLVISNAGAAPLTQElaSPYIFRTSFSNGQYDAPFGQYAYeKLGYRRIAVMASDYAAGHEQAGAFARTFK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 190 AGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLdKAGIKVIGPGDVMDDDLLNGMGDA 269
Cdd:cd06360 161 QAGGKVVQEIYPPLGTADFAPYLARIQQDAADAVWAFFAGADAIRFVKQYDEYGL-KGKLPLVGIGGLVDDAILPEQGDA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 270 ALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKT-DGDALVAAMKGMKWESPRGP 348
Cdd:cd06360 240 ALGIVSYLHYSAALDTPENKAFVQAYRKKYGRDPGLYAEGGYVAARAIAEALEAVKGNVeDKEAFLEALRKVRFEAPRGP 319
|
330 340 350
....*....|....*....|....*....|....*....
gi 639173078 349 ISIDPDtRDIVQNVYIRKVGKVDGELYNVEFETFEAVKD 387
Cdd:cd06360 320 FRFDPY-QQAVVTTYIRRVEKVDGKLVNVVIDRIPDVDQ 357
|
|
| LivK |
COG0683 |
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ... |
29-378 |
2.81e-77 |
|
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];
Pssm-ID: 440447 [Multi-domain] Cd Length: 314 Bit Score: 241.37 E-value: 2.81e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 29 EDSFKIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGV 106
Cdd:COG0683 1 ADPIKIGVLLPLTGPYAALGQPIKNGAELAVEEINAAggVLGRKIELVVEDDASDPDTAVAAARKLIDQDKVDAIVGPLS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 107 TPAALAAAPLATQGKIPEIVMAAGTSIIT--EKSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLTSDYAPGNDALTS 183
Cdd:COG0683 81 SGVALAVAPVAEEAGVPLISPSATAPALTgpECSPYVFRTAPSDAQQAEALADYLAKKlGAKKVALLYDDYAYGQGLAAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 184 FKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKagikvigpgdvmdddll 263
Cdd:COG0683 161 FKAALKAAGGEVVGEEYYPPGTTDFSAQLTKIKAAGPDAVFLAGYGGDAALFIKQAREAGLKG----------------- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 264 ngmgdaalgavtahiysaahpsQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTgGKTDGDALVAAMKGMKWE 343
Cdd:COG0683 224 ----------------------PLNKAFVKAYKAKYGREPSSYAAAGYDAALLLAEAIEKA-GSTDREAVRDALEGLKFD 280
|
330 340 350
....*....|....*....|....*....|....*
gi 639173078 344 SPRGPISIDPDtRDIVQNVYIRKVgKVDGELYNVE 378
Cdd:COG0683 281 GVTGPITFDPD-GQGVQPVYIVQV-KADGKFVVVE 313
|
|
| PBP1_Nba-like |
cd06359 |
type 1 periplasmic binding component of active transport systems predicted to be involved in ... |
33-367 |
1.00e-75 |
|
type 1 periplasmic binding component of active transport systems predicted to be involved in 2-nitrobenzoic acid degradation pathway; This group includes the type 1 periplasmic binding component of active transport systems that are predicted to be involved in 2-nitrobenzoic acid degradation pathway; their substrate specificities are not well characterized.
Pssm-ID: 380582 [Multi-domain] Cd Length: 333 Bit Score: 237.92 E-value: 1.00e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAALA 112
Cdd:cd06359 1 KIGFITTLSGPAAVLGQDMRDGFNLALEQLGGKLGGLPVEVVVEDDQLKPDVAKQAAERLIERDKVDFVTGIIFSNVMLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 113 AAPLATQGKIPEIVMAAGTSIITEK--SPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEHFAa 190
Cdd:cd06359 81 VVKPVVDSKVFYISANAGPSDLAGKgcNPNFFVTSWQNDQLHEAAGKYANDKGYKRVYLLAPNYQAGKDALAGFKRTYK- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 191 ggGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLdKAGIKVIGPGDVMDDDLLNGMGDAA 270
Cdd:cd06359 160 --GEVVGEIYTPLGQLDFSAELAQIRAAKPDAVFAFYPGGMGVNFVKQYAQAGL-KKKIPLYTVGTLDDEDLLPAMGDAA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 271 LGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKT-DGDALVAAMKGMKWESPRGPI 349
Cdd:cd06359 237 LGVLSVSQWSPDLDNPENKRFVAAFRKKYGRPPSNYAAQGYDAALLIDAAVKAVGGDLsDKDALRAALRKADFKSVRGAF 316
|
330
....*....|....*...
gi 639173078 350 SIDPDTRDIvQNVYIRKV 367
Cdd:cd06359 317 RFNNNQFPI-QDFYLREV 333
|
|
| Peripla_BP_6 |
pfam13458 |
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ... |
33-367 |
1.19e-69 |
|
Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.
Pssm-ID: 433225 [Multi-domain] Cd Length: 342 Bit Score: 222.53 E-value: 1.19e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGD--TIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:pfam13458 3 KIGVLTPLSGPYASSGKSSRAGARAAIEEINAagGVNGRKIELVVADDQGDPDVAAAAARRLVDQDGVDAIVGGVSSAVA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSiiTEKSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLTSDYAPGNDALTSFKEHFA 189
Cdd:pfam13458 83 LAVAEVLAKKGVPVIGPAALTG--EKCSPYVFSLGPTYSAQATALGRYLAKElGGKKVALIGADYAFGRALAAAAKAAAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 190 AGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKAGIKVIGPGdVMDDDLLNGMGDA 269
Cdd:pfam13458 161 AAGGEVVGEVRYPLGTTDFSSQVLQIKASGADAVLLANAGADTVNLLKQAREAGLDAKGIKLVGLG-GDEPDLKALGGDA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 270 ALGAVTAHIYSAAHPSQANKDFVAAYKKAFG-NRPGFMAVGGYDGIHLIYEALKKTgGKTDGDALVAAMKGMKWESPRGP 348
Cdd:pfam13458 240 AEGVYATVPFFPDLDNPATRAFVAAFAAKYGeAPPTQFAAGGYIAADLLLAALEAA-GSPTREAVIAALRALPYDGPFGP 318
|
330
....*....|....*....
gi 639173078 349 ISIDPDTRDIVQNVYIRKV 367
Cdd:pfam13458 319 VGFRAEDHQAVHCMYLVQV 337
|
|
| PBP1_As_SBP-like |
cd06330 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
33-364 |
6.84e-60 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.
Pssm-ID: 380553 [Multi-domain] Cd Length: 342 Bit Score: 197.40 E-value: 6.84e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQ--HGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd06330 1 KIGVITPLSGAAAVYGEPARNGAELAVEEinAAGGILGRKIELVVRDDKGKPDEAVRAARELVLQEGVDFLIGTISSGVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEK--SPYIVRTSFTLPQSSTIIGDWAVKN--GIKKVATLTSDYAPGNDALTSFKE 186
Cdd:cd06330 81 LAVAPVAEELKVLFIATDAATDRLTEEnfNPYVFRTSPNTYMDAVAAALYAAKKppDVKRWAGIGPDYEYGRDSWAAFKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 187 HFAAGGG--EIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKaGIKVIGPGDVmDDDLLN 264
Cdd:cd06330 161 ALKKLKPdvEVVGELWPKLGATDYTAYITALLAAKPDGVFSSLWGGDLVTFVKQAKPYGLFD-KTKVVSGLGG-GSEVLQ 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 265 GMGDAALGAV--TAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGkTDGDALVAAMKGMKW 342
Cdd:cd06330 239 ALGKEMPEGLigGGRYPFGWPDTPLNKAFVEAYRAKYGEYPTYWAYEAYAAVMALKAAIEKAGS-TDTDKVIAALEGLTF 317
|
330 340
....*....|....*....|..
gi 639173078 343 ESPRGPISIDPDTRDIVQNVYI 364
Cdd:cd06330 318 DTPGGKITIRAEDHQAVQPVVV 339
|
|
| PBP1_ABC_LivK_ligand_binding-like |
cd06347 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-366 |
3.27e-58 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380570 [Multi-domain] Cd Length: 334 Bit Score: 192.76 E-value: 3.27e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd06347 1 KIGVIGPLTGEAAAYGQPALNGAELAVDEINAAggILGKKIELIVYDNKSDPTEAANAAQKLIDEDKVVAIIGPVTSSIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLT---SDYAPGndaLT-SFK 185
Cdd:cd06347 81 LAAAPIAQKAKIPMITPSATNPLVTKGGDYIFRACFTDPFQGAALAKFAYEElGAKKAAVLYdvsSDYSKG---LAkAFK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 186 EHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAmfVFVPAG--QGGNFMKQYAERGLDkagIKVIGPGDVMDDDLL 263
Cdd:cd06347 158 EAFEKLGGEIVAEETYTSGDTDFSAQLTKIKAANPDV--IFLPGYyeEAALIIKQARELGIT---APILGGDGWDSPELL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 264 NGMGDAALGAV-TAHiYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKTDGDALVAAMKGMKW 342
Cdd:cd06347 233 ELGGDAVEGVYfTTH-FSPDDPSPEVQEFVKAYKAKYGEPPNAFAALGYDAVMLLADAIKRAGSTDPEAIRDALAKTKDF 311
|
330 340
....*....|....*....|....
gi 639173078 343 ESPRGPISIDPDtRDIVQNVYIRK 366
Cdd:cd06347 312 EGVTGTITFDPN-GNPIKPAVILE 334
|
|
| PBP1_ABC_ligand_binding-like |
cd19980 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-352 |
1.87e-57 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380635 [Multi-domain] Cd Length: 334 Bit Score: 190.90 E-value: 1.87e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd19980 1 KIGVIAPLSGPVAALGQQVLNGAKLAVEEINAKggVLGRKLELVVEDDKCPPAEGVAAAKKLITDDKVPAIIGAWCSSVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEK-SPYIVRTSFTLPQSSTIIGDWAVKNG-IKKVATLTSDYAPGNDALTSFKEHF 188
Cdd:cd19980 81 LAVMPVAERAKVPLVVEISSAPKITEGgNPYVFRLNPTNSMLAKAFAKYLADKGkPKKVAFLAENDDYGRGAAEAFKKAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 189 AAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKagiKVIGPGDVMDDDLLNGMGD 268
Cdd:cd19980 161 KAKGVKVVATEYFDQGQTDFTTQLTKLKAANPDAIFVVAETEDGALILKQARELGLKQ---QLVGTGGTTSPDLIKLAGD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 269 AALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKTDGDALVAAMKGMKWESPRGP 348
Cdd:cd19980 238 AAEGVYGASIYAPTADNPANKAFVAAYKKKYGEPPDKFAALGYDAVMVIAEAIKKAGSTDPEKIRAAALKKVDYKGPGGT 317
|
....
gi 639173078 349 ISID 352
Cdd:cd19980 318 IKFD 321
|
|
| PBP1_ABC_transporter_LIVBP-like |
cd06268 |
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the ... |
33-317 |
3.94e-57 |
|
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily; Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.
Pssm-ID: 380492 [Multi-domain] Cd Length: 298 Bit Score: 188.69 E-value: 3.94e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd06268 1 KIGVVVPLTGPYADYGEEILRGVALAVEEINAAggINGRKLELVIADDQGDPETAVAVARKLVDDDKVLAVVGHYSSSVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEK-SPYIVRTSFTLPQSSTIIGDWAVKNG-IKKVATLTSDYAPGNDALTSFKEHF 188
Cdd:cd06268 81 LAAAPIYQEAGIPLISPGSTAPELTEGgGPYVFRTVPSDAMQAAALADYLAKKLkGKKVAILYDDYDYGKSLADAFKKAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 189 AAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGDVMDDDLLNGMGD 268
Cdd:cd06268 161 KALGGEIVAEEDFPLGTTDFSAQLTKIKAAGPDVLFLAGYGADAANALKQARELGLK---LPILGGDGLYSPELLKLGGE 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 639173078 269 AALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLI 317
Cdd:cd06268 238 AAEGVVVAVPWHPDSPDPPKQAFVKAYKKKYGGPPSWRAATAYDATQAL 286
|
|
| PBP1_SBP-like |
cd06328 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
33-364 |
5.56e-54 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative and gram-positive bacteria. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380551 [Multi-domain] Cd Length: 336 Bit Score: 181.73 E-value: 5.56e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKL---YMQQHGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPA 109
Cdd:cd06328 1 KIGVITSLTGPLAAYGKQTERGFELgleYATDGTMEVDGRKIEVIVKDDQGDPDTAKAAATELIGDDGVDILVGTVSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 110 ALAAAPLATQGKIPEIVMAAGTSIITEK--SPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEH 187
Cdd:cd06328 81 ALALAPVAEQNKKILIVGPAAADSITGEnwNKYTFRTSRNSWQDAIAGAKALADPLGKSVAFLAQDYAFGQDGVAAFKKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 188 FAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVfVPAGQGGNFM-KQYAERGLDkAGIKVIGPGDVMDDdlLNGM 266
Cdd:cd06328 161 LEAKGGKIVGEELVPVTTTDFTPYLQRILDAKPDVLFV-AWAGTGALTLwQQLADQGVL-DDIKVVTGGPDIAT--LAAL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 267 GDAALGAVTAHIYSAAHP-SQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKTDGDALVAAMKGMKWESP 345
Cdd:cd06328 237 GDALPGIEGLTYYYYGLPkNPVNDWLVKAHKERYNAPPDLFTAGGFAAAQAVVRALEKAGGDTDVEKLIAALEGLTFETP 316
|
330
....*....|....*....
gi 639173078 346 RGPISIDPDTRDIVQNVYI 364
Cdd:cd06328 317 KGKMTIRAEDHQALQPMYI 335
|
|
| PBP1_ABC_HAAT-like |
cd06349 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-367 |
1.10e-51 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380572 [Multi-domain] Cd Length: 338 Bit Score: 175.84 E-value: 1.10e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQ----HGdtIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTP 108
Cdd:cd06349 1 KIGVSGPLTGDNAEYGQQFKNGVELAVDEinaaGG--VNGRKLELVVYDDQGDPKEAVNIAQKFVSDDKVVAVIGDFSSS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 109 AALAAAPLATQGKIPEIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATL--TSDYapGNDALTSFK 185
Cdd:cd06349 79 CSMAAAPIYEEAGLVQISPTASHPDFTKGGDYVFRNSPTQAVEAPFLADYAVKKlGAKKIAIIylNTDW--GVSAADAFK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 186 EHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGDVMDDDLLNG 265
Cdd:cd06349 157 KAAKALGGEIVATEAYLPGTKDFSAQITKIKNANPDAIYLAAYYNDAALIAKQARQLGWD---VQIFGSSSLYSPEFIEL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 266 MGDAALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGgkTDGDALVAAMKGMK-WES 344
Cdd:cd06349 234 AGDAAEGVYLSSPFFPESPDPEVKEFVKAYKAKYGEDPDDFAARAYDAVNILAEAIEKAG--TDREAIRDALANIKdFSG 311
|
330 340
....*....|....*....|...
gi 639173078 345 PRGPISIDPDtRDIVQNVYIRKV 367
Cdd:cd06349 312 LTGTITFDEN-GDVLKSLTILVV 333
|
|
| PBP1_ABC_HAAT-like |
cd06348 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-367 |
1.32e-51 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380571 [Multi-domain] Cd Length: 342 Bit Score: 175.88 E-value: 1.32e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQ--HGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd06348 1 KIGVALSLTGPGALYGQSQKNGAQLAVEEinAAGGVGGVKIELIVEDTAGDPEQAINAFQKLINQDKVLAILGPTLSSEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPeiVMAAGTSI--ITEKSPYIVRTSftLPQSSTI---IGDWAVKNGIKKVATLT-SDYAPGNDALTSF 184
Cdd:cd06348 81 FAADPIAQQAKVP--VVGISNTApgITDIGPYIFRNS--LPEDKVIpptVKAAKKKYGIKKVAVLYdQDDAFTVSGTKVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 185 KEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKAgikVIGPGDVMDDDLLN 264
Cdd:cd06348 157 PAALKKNGVEVLDTETFQTGDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGP---IVGGNGFNSPDLIK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 265 GMGDAALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKTDGDALVAAMKGMKW-- 342
Cdd:cd06348 234 LAGKAAEGVIVGSAWSPDNPDPKNQAFVAAYKEKYGKEPDQFAAQAYDAAYILAEAIKKAGSTTDRADLRDALARILIak 313
|
330 340
....*....|....*....|....*..
gi 639173078 343 --ESPRGPISIDPDtRDIVQNVYIRKV 367
Cdd:cd06348 314 dfEGPLGPFSFDAD-RDGIQPPVVLIV 339
|
|
| PBP1_AmiC-like |
cd06331 |
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system ... |
33-364 |
1.92e-50 |
|
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); This group includes the type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF), found in bacteria and Archaea. AmiC controls expression of the amidase operon by a ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon is induced. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380554 [Multi-domain] Cd Length: 333 Bit Score: 172.40 E-value: 1.92e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd06331 1 KIGLLTPLSGPASVYGRAIANGAELAVEEINAAggVLGRPVELVVEDDASDPATAVAAARRLIQQDKVDAIVGPITSATR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEI--VMAAGTsiitEKSPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEHF 188
Cdd:cd06331 81 NAVAPVAERAKVPLLypTFYEGG----ECSPYLFCFGEVPNQQLDPLIPWLMEEYGKKFYLIGSDYVWPRTMNDAARRVI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 189 AAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLdKAGIKVIGPGdvMDDDLLNGMGD 268
Cdd:cd06331 157 EAHGGEVVGEEYLPLGTTDFSSVIEKIKASGADVVLSTLVGADAVTFLKQFAAAGL-RRKVRIAALL--FDENTLAGLGA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 269 AAL-GAVTAHIYSAAHPSQANKDFVAAYKKAFG---NRPGFMAVGGYDGIHLIYEALKKTgGKTDGDALVAAMKGMKWES 344
Cdd:cd06331 234 EAAeGIYSVLSYFQSLDTPENKAFVAAYRKKFGedaPPITSLSEAAYEAVHLYAAAVEKA-GSTDPEAVIAALPGVSFDG 312
|
330 340
....*....|....*....|
gi 639173078 345 PRGPISIDPDTRDIVQNVYI 364
Cdd:cd06331 313 PQGPVTMDPDNHHVRLNLYI 332
|
|
| PBP1_ABC_ligand_binding-like |
cd06335 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
33-341 |
2.99e-48 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380558 [Multi-domain] Cd Length: 348 Bit Score: 167.02 E-value: 2.99e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd06335 1 KIGVIGPLTGPSAELGESARRGVELAVEEINAAggILGRKIELVERDDEANPTKAVQNAQELIDKEKVVAIIGPTNSGVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIV-MAAGTSIIT---EKSPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKE 186
Cdd:cd06335 81 LATIPILQEAKIPLIIpVATGTAITKppaKPRNYIFRVAASDTLQADFLVDYAVKKGFKKIAILHDTTGYGQGGLKDVEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 187 HFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMkqyaeRGLDKAGIKV--IGPGDVMDDDLLN 264
Cdd:cd06335 161 ALKKRGITPVATESFKIGDTDMTPQLLKAKDAGADVILVYGLGPDLAQIL-----KAMEKLGWKVplVGSWGLSMPNFIE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 265 GMGDAALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFM---AVGGYDGIHLIYEALKKtGGKTDGDALVAAMKGMK 341
Cdd:cd06335 236 LAGPLAEGTIMTQTFIEDYLTPRAKKFIDAYKKKYGTDRIPSpvsAAQGYDAVYLLAAAIKQ-AGSTDGKKIRAALENLK 314
|
|
| PBP1_SBP-like |
cd19989 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
33-317 |
7.01e-48 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380644 [Multi-domain] Cd Length: 299 Bit Score: 164.76 E-value: 7.01e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd19989 1 KIGVLTPLSGPYAALGEEARRGAQLAVEEINAAggILGRPVELVVEDTEGKPATAVQKARKLVEQDGVDFLTGAVSSAVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEK--SPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEHF 188
Cdd:cd19989 81 LAVAPKAAELKVPYLVTVAADDELTGEncNRYTFRVNTSDRMIARALAPWLAENGGKKWYIVYADYAWGQSSAEAFKEAI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 189 AAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKAgIKVIGPGDVMDDDLLNGMGD 268
Cdd:cd19989 161 EELGGEVVGTLFAPLGTTDFSSYITQISDSGADGLLLALAGSDAVNFLKQAGQFGLGKK-YKIVGGILSIEPLALPALGD 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 639173078 269 AALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLI 317
Cdd:cd19989 240 AAEGVYGGVRYPPTLDTPANRAFVEAYEKEYGEAPDNFAGEAYEAMQAL 288
|
|
| PBP1_ABC_RPA1789-like |
cd06333 |
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, ... |
33-341 |
1.83e-47 |
|
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs; This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380556 [Multi-domain] Cd Length: 342 Bit Score: 165.03 E-value: 1.83e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd06333 1 KIGAILSLTGPAASLGIPERNAVELLVEQINAAggINGRKLELIVYDDESDPTKAVTNARKLIEEDKVDAIIGPSTTGES 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEHFAA 190
Cdd:cd06333 81 LAVAPIAEEAKVPLISLAGAAAIVEPVRKWVFKTPQSDSLVAEAILDYMKKKGIKKVALLGDSDAYGQSGRAALKKLAPE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 191 GGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGDVMDDDLLNGMGDAA 270
Cdd:cd06333 161 YGIEIVADERFARTDTDMTAQLTKIRAAKPDAVLVWASGPPAALVAKNLRQLGYK---GPIYQSHGAANQDFIKLAGKAA 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639173078 271 LGA--VTAHIYSAAHPSQAN------KDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKtGGKTDGDALVAAMKGMK 341
Cdd:cd06333 238 EGVilPAGKLLVADQLPDSDpqkkvlLEFVKAYEAKYGEGPSTFAGHAYDALLLLVEAIEP-AGGTDRAALRDALENTK 315
|
|
| PBP1_ABC_ligand_binding-like |
cd06345 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-354 |
4.88e-45 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380568 [Multi-domain] Cd Length: 356 Bit Score: 158.97 E-value: 4.88e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTggqASTGKQIDNAIKLYMQQ---HGDtIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPA 109
Cdd:cd06345 1 KIGVLGPLS---APAGEAMERGAELAVEEinaAGG-ILGRKVELVVADTQGKPEDGVAAAERLITEDKVDAIVGGFRSEV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 110 ALAAAPLATQGKIPEIVMAAGTSIIT-------EKSPYIVRTSFTLPQSSTIIGDWAV-----KNGIKKVATLTSDYAPG 177
Cdd:cd06345 77 VLAAMEVAAEYKVPFIVTGAASPAITkkvkkdyEKYKYVFRVGPNNSYLGATVAEFLKdllveKLGFKKVAILAEDAAWG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 178 NDALTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKAGIKVIGPGdv 257
Cdd:cd06345 157 RGIAEALKKLLPEAGLEVVGVERFPTGTTDFTPILSKIKASGADVIVTIFSGPGGILLVKQWAELGVPAPLVGINVPA-- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 258 MDDDLLNGMGDAALGAVTAhiySAAHPSQAN----KDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGkTDGDAL 333
Cdd:cd06345 235 QDPEFWENTGGAGEYEITL---AFAAPKAKVtpktKPFVDAYKKKYGEAPNYTAYTAYDAIYILAEAIERAGS-TDPDAL 310
|
330 340
....*....|....*....|.
gi 639173078 334 VAAMKGMKWESPRGPISIDPD 354
Cdd:cd06345 311 VKALEKTDYEGVRGRIKFDKK 331
|
|
| PBP1_ABC_LIVBP-like |
cd06342 |
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active ... |
33-363 |
1.25e-44 |
|
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.
Pssm-ID: 380565 [Multi-domain] Cd Length: 334 Bit Score: 157.30 E-value: 1.25e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGD--TIAGKKIEVILKDDAALPDKTKTAAQELiVSEKVNAIAGFGVTPAA 110
Cdd:cd06342 1 KIGVAGPLTGPNAALGQDIRNGAELAVDEINAkgGGLGFKIELVAQDDACDPAQAVAAAQKL-VADGVVAVIGHYNSGAA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEKS-PYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATL--TSDYapGNDALTSFKE 186
Cdd:cd06342 80 IAAAPIYAEAGIPMISPSATNPKLTEQGyKNFFRVVGTDDQQGPAAADYAAKTlKAKRVAVIhdGTAY--GKGLADAFKK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 187 HFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGDVMDDDLLNGM 266
Cdd:cd06342 158 ALKALGGTVVGREGITPGTTDFSALLTKIKAANPDAVYFGGYYPEAGLLLRQLREAGLK---APFMGGDGIVSPDFIKAA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 267 GDAALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTgGKTDGDALVAAMKGMKWESPR 346
Cdd:cd06342 235 GDAAEGVYATTPGAPPEKLPAAKAFLKAYKAKFGEPPGAYAAYAYDAAQVLLAAIEKA-GSTDRAAVAAALRATDFDGVT 313
|
330
....*....|....*....
gi 639173078 347 GPISIDP--DTRDIVQNVY 363
Cdd:cd06342 314 GTISFDAkgDLTGPAFTVY 332
|
|
| PBP1_ABC_ligand_binding-like |
cd06343 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
30-367 |
7.47e-42 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however its ligand specificity has not been determined experimentally.
Pssm-ID: 380566 [Multi-domain] Cd Length: 355 Bit Score: 150.41 E-value: 7.47e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 30 DSFKIGLILPMTGGQASTGKQIDNAIKLYMQQ---HGDtIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGV 106
Cdd:cd06343 5 DEIKIGTSLPLSGPAAAYGKPVRAGAAAYFDEvnaAGG-INGRKIELIVEDDGYDPARAVAAVRKLVEQDKVFAIVGGLG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 107 TPAALAAAPLATQGKIPEIVMAAGTSIITE-KSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLTSDYAPGNDALTSF 184
Cdd:cd06343 84 TPTNLAVRPYLNEAGVPQLFPATGASALSPpPKPYTFGVQPSYEDEGRILADYIVETlPAAKVAVLYQNDDFGKDGLEGL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 185 KEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKagiKVIGPGDVMDDDLLN 264
Cdd:cd06343 164 KEALKAYGLEVVAEETYEPGDTDFSSQVLKLKAAGADVVVLGTLPKEAAAALKEAAKLGWKP---TFLGSSVSADPTTLA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 265 GM-GDAALGAVTAHIYS--AAHPSQANKDFVAAYKKAF-GNRPGFMAVGGYDGIHLIYEALKKTGGKTDGDALVAAMKGM 340
Cdd:cd06343 241 KAgGDAAEGVYSASYLKdpTDADDPAVKEFREAYKKYFpDDPPNAYALYGYAAAQVFVEALKRAGKDLTREGLIKALESL 320
|
330 340 350
....*....|....*....|....*....|
gi 639173078 341 KWESPRG---PISIDPDTRDIVQNVYIRKV 367
Cdd:cd06343 321 KDFDDGGpgpPVTFSPDDHRGIESMYLVQV 350
|
|
| PBP1_ABC_ligand_binding-like |
cd06336 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
33-341 |
9.41e-42 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380559 [Multi-domain] Cd Length: 345 Bit Score: 149.69 E-value: 9.41e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQH----GDTIAGK--KIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGV 106
Cdd:cd06336 1 KIGFLGPLSGPAAAWGLPMLRGLELAADEInaagGIKVGGKkyKVEVVSYDDKYTPAEAVAAARRLVSQDGVKFIFGPGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 107 TPAALAAAPLATQGKIPEIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLTSDYAPGNDALTSFK 185
Cdd:cd06336 81 SAIAAAVQPVTERNKVLLLTAAFSDPILGPDNPLLFRIPPTPYEYAPPFIKWLKKNgPIKTVALIAPNDATGKDWAAAFV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 186 EHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFV-FVPAGQGGNFMKQYAERGLDkaGIKVIGPGDVMDDDLLN 264
Cdd:cd06336 161 AAWKAAGGEVVAEEFYDRGTTDFYPVLTKILALKPDALDLgGSSPGPAGLIIKQARELGFK--GPFVSEGGAKADEILKE 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639173078 265 GMGDAALGAV-TAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKTDGDALVAAMKGMK 341
Cdd:cd06336 239 VGGEAAEGFIgVLPADDDPIASPGAKAFVERYKKKYGEPPNSESALFYDAAYILVKAMEKAGTVDDTKKIRAALAMLS 316
|
|
| PBP1_ABC_ligand_binding-like |
cd19984 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-318 |
2.04e-41 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380639 [Multi-domain] Cd Length: 296 Bit Score: 147.75 E-value: 2.04e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd19984 1 KIGVILPLTGDAASYGEDMKNGIELAVEEINAAggINGKKIELIYEDSKCDPKKAVSAANKLINVDKVKAIIGGVCSSET 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLT--SDYAPGNDalTSFKEHF 188
Cdd:cd19984 81 LAIAPIAEQNKVVLISPGASSPEITKAGDYIFRNYPSDAYQGKVLAEFAYNKLYKKVAILYenNDYGVGLK--DVFKKEF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 189 AAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGDVMDDDLLNGMGD 268
Cdd:cd19984 159 EELGGKIVASESFEQGETDFRTQLTKIKAANPDAIFLPGYPKEGGLILKQAKELGIK---APILGSDGFEDPELLEIAGE 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 639173078 269 AALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIY 318
Cdd:cd19984 236 AAEGVIFTYPAFDDSSEKKQKFFFYRYKEKYGKEPDIYAALAYDAVMILA 285
|
|
| PBP1_AmiC |
cd06357 |
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding ... |
33-388 |
6.90e-38 |
|
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family; This group includes the periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family. AmiC controls expression of the amidase operon by the ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon are induced.
Pssm-ID: 380580 [Multi-domain] Cd Length: 357 Bit Score: 139.64 E-value: 6.90e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQ---HGDtIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGfgvtpa 109
Cdd:cd06357 1 RVGLLFSQTGVTAIIEQSMLNGALLAIEEinaAGG-VNGRPIEPVVYDPASDPDRYRELAERLLLEDGVRHIFG------ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 110 alaaaplatqgkipeivmaAGTS--------IIT---------------EKSPYIVRTSFTLPQSSTIIGDWAVKNGIKK 166
Cdd:cd06357 74 -------------------CYTSasrkavlpVVErhnallwyptpyegfEYSPNVIYTGAVPNQHLLPLARYLLAHFGKR 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 167 VATLTSDYAPGNDALTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDK 246
Cdd:cd06357 135 VFLVGSNYVYPWESNRVARELIEASGGEVVGERYVPLGDTDFAEIIEEIKSLKPDVVFSTLVGDSIYAFYRAYAEAGLDP 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 247 AGIKVIGPgdVMDDDLLNGMG-DAALGAVTAHIYSAAHPSQANKDFVAAYKKAFG--NRPGFMAVGGYDGIHLIYEALKK 323
Cdd:cd06357 215 ADMPIASL--TTSEAEVAAIGaEAAAGHYTSAPYFQSIDTPENRAFVEAYRARFGddAVTSAVAEAAYFQVHLLARAIER 292
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639173078 324 TgGKTDGDALVAAMKGMKWESPRGPISIDPDTRDIVQNVYIRKVGKvDGeLYNVEFETFEAVK-DP 388
Cdd:cd06357 293 A-GSDDPEAIRAALYGQEFDAPQGPVRIDPDNNHTWLTPRIGRANA-DG-QFDIVWESDEPVApDP 355
|
|
| PBP1_ABC_ligand_binding-like |
cd06338 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
33-354 |
8.26e-37 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380561 [Multi-domain] Cd Length: 347 Bit Score: 136.56 E-value: 8.26e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQ----HGDTIAGKK--IEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGV 106
Cdd:cd06338 1 KIGASLSLTGPFAGEGKAQKRGYELWVEDvnaaGGVKGGGKKrpVELVYYDDQSDPATAVRLYEKLITEDKVDLLLGPYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 107 TPAALAAAPLATQGKIPEIVM-AAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKNG--IKKVATLTSDYAPGNDALTS 183
Cdd:cd06338 81 SGLTLAAAPVAEKYGIPMIAGgAASDSIFERGYKYVFGVLPPASDYAKGLLDLLAELGpkPKTVAIVYEDDPFGKEVAEG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 184 FKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPG-DVMDDDL 262
Cdd:cd06338 161 AREAAKKAGLEVVYDESYPPGTTDFSPLLTKVKAANPDILLVGGYPPDAITLVRQMKELGYN---PKAFFLTvGPAFPAF 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 263 LNGMGDAALGAVTAHIYSAAHPSQA---NKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTgGKTDGDALVAAMKG 339
Cdd:cd06338 238 REALGKDAEGVLGPSQWEPSLPYKVfpgAKEFVKAYKEKFGEEPSYHAAAAYAAGQVLQQAIEKA-GSLDPEKVRDALAS 316
|
330
....*....|....*
gi 639173078 340 MKWESPRGPISIDPD 354
Cdd:cd06338 317 LDFDTVYGPIKFDET 331
|
|
| PBP1_SBP-like |
cd06327 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
33-375 |
8.74e-37 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380550 [Multi-domain] Cd Length: 336 Bit Score: 136.16 E-value: 8.74e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTG-GQASTGKQIDNAIKLYMQQHGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAAL 111
Cdd:cd06327 1 RIGVLTDLSGvYADLSGPGSVEAAKMAVEDFGGKVLGRPIEVVSADHQNKPDVASAIAREWYDRDGVDAIVDVPNSAVAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 112 AAAPLATQGKIPEIVMAAGTSIITEK--SPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEHFA 189
Cdd:cd06327 81 AVQKLAKEKKKIAIVTGAGSSDLTGKacSPYGVHWAYDTYALARGTVKALVKQGGKSWFFITADYAFGHSLEADATAAVK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 190 AGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKAGIKVIGPGDVMDDdlLNGMG-D 268
Cdd:cd06327 161 AAGGKVVGSVRHPLGTTDFSSFLLQAQASGADVIALANAGADLVNAVKQAREFGLTDGGQKLAALLLFITD--IHALGlD 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 269 AALGAVTAHIYSAAHpSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGkTDGDALVAAMKGMKWESPrgp 348
Cdd:cd06327 239 AAQGLYLTTAFYWDR-DDATRAWAKRFFARTGKMPTMLQAGVYSAVLHYLKAVKAAGT-DDADAVVAKMREMPVNDF--- 313
|
330 340
....*....|....*....|....*..
gi 639173078 349 isidpdtrdIVQNVYIRKVGKVDGELY 375
Cdd:cd06327 314 ---------FAKNGRIRADGRVVHDMY 331
|
|
| PBP1_ABC_HAAT-like |
cd19988 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-317 |
9.41e-36 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380643 [Multi-domain] Cd Length: 302 Bit Score: 132.79 E-value: 9.41e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd19988 1 KIGVFGPLSGDAAPYGQAMLQGAELAVEEINAAggILGIPIELVVEDDEGLPAASVSAAKKLIYQDKVWAIIGSINSSCT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEKS-PYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATL--TSDYapGNDALTSFKE 186
Cdd:cd19988 81 LAAIRVALKAGVPQINPGSSAPTITESGnPWVFRCTPDDRQQAYALVDYAFEKlKVTKIAVLyvNDDY--GRGGIDAFKD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 187 HFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGDVMDDDLLNGM 266
Cdd:cd19988 159 AAKKYGIEVVVEESYNRGDKDFSPQLEKIKDSGAQAIVMWGQYTEGALIAKQARELGLK---QPLFGSDGLVTPKFIELA 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 639173078 267 GDAALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLI 317
Cdd:cd19988 236 GDAAEGAIATTPFLPDSDDPKVSAFVEKYKKRYGEEPDVFAAQAYDAMNIL 286
|
|
| PBP1_ABC_ligand_binding-like |
cd06340 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
33-365 |
2.95e-35 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380563 [Multi-domain] Cd Length: 352 Bit Score: 132.68 E-value: 2.95e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQ----QHGDT-IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVT 107
Cdd:cd06340 1 KIGVLYPLSGPLALIGQEAKRGAELAVDeinaAGGIKsLGGAKIELVVADTQSDPEVAASEAERLITQEGVVAIIGAYSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 108 PAALAAAPLATQGKIPEIVMAAGTSIITEKS-PYIVRTSFTLPQSSTI----IGDWAVKNG--IKKVATLTSDYAPGNDA 180
Cdd:cd06340 81 SVTLAASQVAERYGVPFVTASAVADEITERGfKYVFRTAPTASQFAEDavdfLKELAKKKGkkIKKVAIIYEDSAFGTSV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 181 LTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFvfvPAGQGGN---FMKQYAERGLDKAGIKVIGPGDV 257
Cdd:cd06340 161 AKGLKKAAKKAGLEVVLDEPYPAGATDLSSEVLKLKAAKPDVVF---ATSYTNDailLLRTMKELGFKPKAIIGVGGGYS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 258 mDDDLLNGMGDAALG--AVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKtGGKTDGDALVA 335
Cdd:cd06340 238 -DPEFLKALGKDAEGvfSVVPWSPDLAKKKPGAKEVNERYKKKYGEDMTGHAARAYTAAWVLADALER-AGSTDPEAIRA 315
|
330 340 350
....*....|....*....|....*....|....*
gi 639173078 336 A-----MKGMKWESPRGPISIDPDTrdivQNVYIR 365
Cdd:cd06340 316 AaaltlDIPEGLIMPGGGVKFDEKG----QNVLAR 346
|
|
| PBP1_FmdD-like |
cd06355 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
33-369 |
1.13e-32 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF), found in Methylophilus methylotrophus, and its homologs from other bacteria. FmdD, a type 1 periplasmic binding protein, is induced by short-chain amides and urea and repressed by excess ammonia, while FmdE and FmdF are hydrophobic transmembrane proteins. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380578 [Multi-domain] Cd Length: 347 Bit Score: 125.38 E-value: 1.13e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIagFG----- 105
Cdd:cd06355 1 KVGILHSLSGTMAISERPLVDATLLAIDEINAAggLLGRKIEPVIEDGASDWPTFAEKAEKLITQDKVAVI--FGcwtsa 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 106 ----VtpaalaaaplatqgkIPeIVMAAGTSII-------TEKSPYIVRTSFTLPQS--STIigDWAVKNGIKKVATLTS 172
Cdd:cd06355 79 srkaV---------------LP-VIEKYNGLLFypvqyegLEQSPNIVYTGATPNQQilPAI--DWLLENLGKRFFLVGS 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 173 DYAPGNDALTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKAGIKVI 252
Cdd:cd06355 141 DYVFPRTANKIIRDQLKALGGEVVGEEYVPLGGTDFDAIVAKIKAFKPDVIVNTLNGDSNIAFFKQLAAAGITASDLPVL 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 253 GPgDVMDDDLLNGMGDAALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMA--VGGYDGIHLIYEALKKtGGKTDG 330
Cdd:cd06355 221 SF-SVSEAELRAIGPEELAGHYAAWNYFQSLDTPENQAFVEAFKAKYGADRVTSDpmEAAYLGVYLWAQAVEK-AGSFDP 298
|
330 340 350
....*....|....*....|....*....|....*....
gi 639173078 331 DALVAAMKGMKWESPRGPISIDPDTRDIVQNVYIRKVGK 369
Cdd:cd06355 299 DAVRAALKGQSFEAPGGTVTVDPENHHLWKPVRIGKVQA 337
|
|
| PBP1_ABC_HAAT-like |
cd19981 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-324 |
6.46e-32 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380636 [Multi-domain] Cd Length: 297 Bit Score: 122.40 E-value: 6.46e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQ--HGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd19981 1 KIGFFAPLTGPAAADGKSALHGAELAVEQinAAGGINGKKVELVVYDDQASPKQAVNIAQKLIEQDKVVAVVSGSYSGPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLTSDYAPGNDALTSFKEHFA 189
Cdd:cd19981 81 RAAAPIFQEAKVPMVSAYAVHPDITKAGDYVFRVAFLGPVQGRAGAEYAVKDlGAKKVAILTIDNDFGKSLAAGFKEEAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 190 AGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGDVMDDDLLNGMGDA 269
Cdd:cd19981 161 KLGAEIVSEYAYALGDRDFRPILTKIKSANPDAIYASGYYAEAAPIVKQARELGIK---VPIIGQEGYDSPKFIEIAGSA 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 639173078 270 ALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKT 324
Cdd:cd19981 238 AEGVIITTSLNRDSDRPITQKFIKEYRKRYGIDPDMVAASTYDAVMVLAGEVQKP 292
|
|
| PBP1_SBP-like |
cd20378 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
33-364 |
7.75e-32 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380668 [Multi-domain] Cd Length: 357 Bit Score: 123.61 E-value: 7.75e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDTiAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAALA 112
Cdd:cd20378 1 TLGGLVSMSGAFAAAGKLADRGMRLAVEEYGGA-LGRPLKYITRDTEGKPGTGVRKVQEAIAQDGARFFIGGTLSSVALA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 113 AAPLATQGKIPEIVmAAGTSIITEK-----------SPY------IVRTSFTLPQsstiigdwavkngIKKVATLTSDYA 175
Cdd:cd20378 80 VSEEAEKAGGVYIT-SGGADEITGSrcnrstfrwsvPTYgairqtVRPVIKAMPK-------------AKRWYTITPQYV 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 176 PGNDALTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLdKAGIKVIGPG 255
Cdd:cd20378 146 FGESLLKNAKEVLKEKGIEHVGNSYHSLGEREFSGYLTKAMAARPDVLLILNFGSQAVDALRQAVSFGL-KRKMKILVAW 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 256 ----DVMDD---DLLNGMgdaALGAVtahiYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGkT 328
Cdd:cd20378 225 ssglDQFQElgpDICEGV---YFGAQ----YWHDVDTPANKALVKVYQAKFKETPSYALAAGYACTRMLLDAIDKAGS-T 296
|
330 340 350
....*....|....*....|....*....|....*.
gi 639173078 329 DGDALVAAMKGMKWESPRGPISIDPDTRDIVQNVYI 364
Cdd:cd20378 297 DPAAVIKALEGLKYDGITGDEEVRAADHQVLKPYYL 332
|
|
| PBP1_ABC_ligand_binding-like |
cd06326 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
34-341 |
1.18e-30 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380549 [Multi-domain] Cd Length: 339 Bit Score: 119.95 E-value: 1.18e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 34 IGLILPMTGGQASTGKQIDNAIKLYMQQ----HGdtIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPA 109
Cdd:cd06326 3 IGQSAPLSGPLAELGREYLAGAKAYFDQvnaaGG--INGRKIRLVTLDDGYDPARTVENTRQLIEQDKVVALFGYVGTAN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 110 ALAAAPLATQGKIPEI-VMAAGTSIITEKSPYI--VRTSFT------LPQSSTIigdwavknGIKKVATLTSDYAPGNDA 180
Cdd:cd06326 81 VEAVLPLLEEAGVPLVgPLTGADSLREPGNPYVfhVRASYAdevekiVRHLATL--------GLKRIAVVYQDDPFGKEG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 181 LTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDK--AGIKVIGPGDVM 258
Cdd:cd06326 153 LAAAEAALAARGLEPVATAAVARNAADVAAAAAALAAAKPQAVVLIAAGKAAAAFIKALRAAGGAAqfYGLSVVGAAALA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 259 DDdllngMGDAALGAVTAHI----YSAAHPSQanKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKTDGDALV 334
Cdd:cd06326 233 KA-----LGDAARGVVVSQVvpnpWSTTLPLV--REYQAAMKAAGPKEPSYASLEGYIAARVLVEALRRAGRNPTRESLV 305
|
....*..
gi 639173078 335 AAMKGMK 341
Cdd:cd06326 306 AALESLG 312
|
|
| PBP1_ABC_ligand_binding-like |
cd06346 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-320 |
6.62e-30 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380569 [Multi-domain] Cd Length: 314 Bit Score: 117.28 E-value: 6.62e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQ---HGDtIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPA 109
Cdd:cd06346 1 KIGALLPLTGPLASLGPPMLAAAELAVEEinaAGG-VLGKKVELVVEDSQTDPTAAVDAARKLVDVEGVPAIVGAASSGV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 110 ALAAAPLATQGKIPEIVMAAGTSIIT--EKSPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEH 187
Cdd:cd06346 80 TLAVASVAVPNGVVQISPSSTSPALTtlEDKGYVFRTAPSDALQGVVLAQLAAERGFKKVAVIYVNNDYGQGLADAFKKA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 188 FAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKagIKVIGPGDVMDDDLLNGMG 267
Cdd:cd06346 160 FEALGGTVTASVPYEPGQTSYRAELAQAAAGGPDALVLIGYPEDGATILREALELGLDF--TPWIGTDGLKSDDLVEAAG 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 639173078 268 DAALGAVTAhIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEA 320
Cdd:cd06346 238 AEALEGMLG-TAPGSPGSPAYEAFAAAYKAEYGDDPGPFAANAYDAVMLLALA 289
|
|
| PBP1_ABC_HAAT-like |
cd19986 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-317 |
1.19e-29 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380641 [Multi-domain] Cd Length: 297 Bit Score: 116.19 E-value: 1.19e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd19986 1 KIGVVAPLTGPAALNGEYQKNGAQLALEEINAAggVLGRPLELVVEDDQGTNTGAVNAVNKLISDDKVVAVIGPHYSTQV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLTSDYAPGNDALTSFKEHFA 189
Cdd:cd19986 81 LAVSPLVKEAKIPVITGGTSPKLTEQGNPYMFRIRPSDSVSAKALAKYAVEElGAKKIAILYDNDDFGTGGADVVTAALK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 190 AGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGDVMDDDLLNGMGDA 269
Cdd:cd19986 161 ALGLEPVAVESYNTGDKDFTAQLLKLKNSGADVIIAWGHDAEAALIARQIRQLGLD---VPVIGSSSFATPTVLLLAGEA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 639173078 270 ALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLI 317
Cdd:cd19986 238 LEGIYSVTDFVPSDPDPKVQAFVKKYKAKYGEDPDLYSAWYYDAMYLL 285
|
|
| PBP1_amide_urea_BP-like |
cd06356 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
33-364 |
1.25e-29 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the type 1 periplasmic-binding proteins that are predicted to have a function similar to that of an active transport system for short chain amides and/or urea in bacteria and Archaea, by sequence comparison and phylogenetic analysis.
Pssm-ID: 380579 [Multi-domain] Cd Length: 334 Bit Score: 117.02 E-value: 1.25e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAiagfgvtpaa 110
Cdd:cd06356 1 KIGSIFDLSGGLNIYGKPMVHAMKLAVEEINAAggLLGRQIELVAYDTQSDMQKYTQYAQQLILRDKVDV---------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 laaaplatqgkipeiVMAAGTSIITE---------KSPYIVRT---------------SFTLPQSSTIIgDWAVKNGIKK 166
Cdd:cd06356 71 ---------------VFGGITSASREairpilrrnKILYFYNTqyeggvcdkntfctgSTPEQQVSPLI-EWAIKKYGKK 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 167 VATLTSDYAPGNDALTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDamFVfVPAGQGGN---FMKQYAERG 243
Cdd:cd06356 135 VYIIAADYNFGQISADWVKKYAKKNGGEVVGEEFFPLDVTDFGPTIQKIQAAKPD--FV-VSLLVGGNhisFYRQWAAAG 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 244 LDKaGIKVI----GPGD---VMDDDLLNGMgdaalgaVTAHIYSAAHPSQANKDFVAAYKKAFGNRP--GFMAVGGYDGI 314
Cdd:cd06356 212 LKK-KIPIVstvfGAGNehkVLSPPELEGM-------YVSYSYFEELDTPANKAFVAKWRAKYGDEPyiNQEAVGVYNAV 283
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 639173078 315 HLIYEALKKtGGKTDGDALVAAMK-GMKWESPRGPISIDPDTRDIVQNVYI 364
Cdd:cd06356 284 YLWAEAVEK-AGSTEREAVIAALEsGISFDGPSGTVTVDPKSHHAIQNVYL 333
|
|
| PBP1_SBP-like |
cd06329 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
33-364 |
1.89e-27 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380552 [Multi-domain] Cd Length: 343 Bit Score: 111.21 E-value: 1.89e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKlYMQQH---GDTIAGKKIEVILKDDAALPDKTKTAAQELIvSEKVNAI---AGFGV 106
Cdd:cd06329 1 KIAFIDPLSGPFASVGEIYLKGLQ-FAIEEinaGGGLLGRKIELVPFDNKGSPQEALIQLKKAI-DQGIRFVlqgNSSAV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 107 TPAALAAAPLATQG----KIPEIVMAAGTSIITEK--SPYIVRTSFTLPQSSTIIGDWAVKNG-IKKVATLTSDYAPGND 179
Cdd:cd06329 79 AGALIDAIEKHNQRnpdkRVLFLNYGAEAPELTGAkcSFWHFRFDANADMKMAALADYMKKDGsIKKVYLINQDYSFGRD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 180 ALTSFKEHFAA--GGGEIVEEVKVPLANP-DFAPFLQRMKDAKPDAMFvfvpAGQGGN----FMKQYAERGLDK--AGIK 250
Cdd:cd06329 159 VAAAAKKNLKKkrPDIEIVGEDLHPLGKVkDFSPYIAKIKASGADTVI----TGNWGNdltlLMKAARDSGLKApfYTYY 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 251 VIGPGdvmdddLLNGMGDAALGAVTAHIYSAAHP-SQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKtGGKTD 329
Cdd:cd06329 235 ADGPG------APAAIGEAGVGRLVAVAYWHPNPkTPELEKFAEAFRAKYGRYPDFNIGRTYMGVEMLAAAIKK-AGSTD 307
|
330 340 350
....*....|....*....|....*....|....*
gi 639173078 330 GDALVAAMKGMKWESPRGPISIDPDTRDIVQNVYI 364
Cdd:cd06329 308 PEKVAKALEGLSFDTPGGPVTMRADDHQAIQPLYI 342
|
|
| Peripla_BP_5 |
pfam13433 |
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic ... |
32-388 |
6.20e-26 |
|
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic binding proteins.
Pssm-ID: 463875 [Multi-domain] Cd Length: 363 Bit Score: 107.29 E-value: 6.20e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 32 FKIGLILPMTGGQASTGKQIDNAIKLYMQQ--HGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIagFGVtpa 109
Cdd:pfam13433 1 IKVGVLHSLTGTMAISERSLKDATLMAIEEinAAGGVLGRKIEPVVVDPASDWPLFAEKARKLIDQDKVRVV--FGC--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 110 alaaaplatqgkipeIVMAAGTSIIT------------------EKSPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLT 171
Cdd:pfam13433 76 ---------------WTSASRKAVLPvferhngllfypvqyegfESSRNIFYTGAAPNQQAIPAVDYLLSELGKRFFLVG 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 172 SDYAPGNDALTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKAGIKV 251
Cdd:pfam13433 141 SDYVYPRTTNRILRAYLKAKGGEVVGERYLPLGSSDWQSIVAKIKAAGPDVVFSTINGDSNVAFYRALRAAGITAEDIPV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 252 IGPgdVMDDDLLNGMG-DAALGAVTAHIYSAAHPSQANKDFVAAYKKAFG-----NRPgfmAVGGYDGIHLIYEALKKTg 325
Cdd:pfam13433 221 MSF--SVAEEELAGMGpEPLVGHLAAWNYFQSLDTPENKAFVAAFKARYGddrvtNDP---MEAAYIGVHLWAQAVEKA- 294
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639173078 326 GKTDGDALVAAMKGMKWESPRGPISIDPDTRDIVQNVYIRKVGKvDGElYNVEFETFEAVK-DP 388
Cdd:pfam13433 295 GTDDPDAVRQAMLGQEFDAPQGPVKIDPENHHTWKPVRIGRIRA-DGQ-FDIVWETDGPVRpDP 356
|
|
| PBP1_ABC_ligand_binding-like |
cd06341 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
33-341 |
8.43e-25 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380564 [Multi-domain] Cd Length: 340 Bit Score: 103.54 E-value: 8.43e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQAST----GKQIDNAIKLYMQQHGdtIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTP 108
Cdd:cd06341 1 KIGLIYPDTGPGAASfsaaRAGAEARFGLANAAGG--INGRKVEYVWCDDQSDPATNLQAARQLVEDEKVFALVGSSSAA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 109 AALAAAPLATQGkIPeIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDAL-TSFKEH 187
Cdd:cd06341 79 SGSANDYLAQAG-IP-VVGGAGVSVWCFRNMFSNFFSLGGGGSTTTYGQYAAALGGTKAAVVVTDIPAASQQLaQQLAAS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 188 FAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGDVMDDDLLNGMG 267
Cdd:cd06341 157 LRAAGVEVVGTAPYAAAAPDYTAVAQAAKAAGADAVVGVLDPDVAARVLKAARAQGLD---LKVALSPSGYDPSVLAAYG 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639173078 268 DAALGAVTA-HIYSAAHPSQANKDFVAA---YKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKTDGDALVAAMKGMK 341
Cdd:cd06341 234 AALAGVSVAsTFLPFEADTPAVKAYRAAmakYAPELQDPLQQFALSGYIAADLFVRGLEAAGGCPTRAAFIKALRDVK 311
|
|
| PBP1_NHase |
cd06358 |
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively ... |
33-364 |
3.58e-24 |
|
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides; This group includes the type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides, which are subsequently converted by amidases to yield free carboxylic acids and ammonia. NHases from bacteria and fungi have been purified and characterized. In Rhodococcus sp., the nitrile hydratase operon consists of six genes encoding NHase regulator 2, NHase regulator 1, amidase, NHase alpha subunit, NHase beta subunit, and NHase activator. The operon produces a constitutive hydratase that has a broad substrate spectrum: aliphatic and aromatic nitriles, mononitriles and dinitriles, hydroxynitriles and amino-nitriles, and a constitutive amidase of equally low substrate specificity. NHases are metalloenzymes containing either cobalt or iron, and therefore can be classified into two subgroups: ferric NHases and cobalt NHases.
Pssm-ID: 380581 [Multi-domain] Cd Length: 333 Bit Score: 101.90 E-value: 3.58e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQ--HGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFgVTPAA 110
Cdd:cd06358 1 RIGLLIPLSGPAGLWGPSCEACAELAAAEinAAGGILGREVELVLIDAGGPPAEVAAAARRLVDDGAVDAIVGM-HTSAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAA---GtsiitEKSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLTSDYAPGNDALTSFKE 186
Cdd:cd06358 80 RQALANAVGGRVPYVYTPLyegG-----ERTPGVYAIGETPEEQLRPALRWLADErRVRRWFLVGNDYVWPRASHAAARR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 187 HFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKagiKVIGPGDVMDDDLLNGM 266
Cdd:cd06358 155 YIARLGGEVVGERFVPLGEDDFERVLARIRASRPDAVLISLVGQDAVDFNRAFAAAGLAG---RILRLSPAIDENVLLAI 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 267 GDAAlgavTAHIYSAAH-----PSQANKDFVAAYKKAFGNR---PGFMAVGGYDGIHLiYEALKKTGGKTDGDALVAAMK 338
Cdd:cd06358 232 GADA----TENLYSASGyfaslRTAANLAFLERYHAAFGDRappLNALGESCYEGVHF-LAALARRAGSLDVRALAAAAE 306
|
330 340
....*....|....*....|....*.
gi 639173078 339 GMKWESPRGPISIDPdtRDIVQNVYI 364
Cdd:cd06358 307 GLTYESPRGAVTLRG--RHARQPVYL 330
|
|
| PBP1_ABC_HAAT-like |
cd06344 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
66-365 |
4.00e-24 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380567 [Multi-domain] Cd Length: 332 Bit Score: 101.53 E-value: 4.00e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 66 IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAAlaaaplatqgkIP--------EIVM----AAGTSI 133
Cdd:cd06344 34 VLGRKIRLVEYDDEASVDKGLAIAQRFADNPDVVAVIGHRSSYVA-----------IPasiiyeraGLLMlspgATAPKL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 134 ITEKSPYIVRTsftLPqSSTIIG----DWAVKNGIKKVATLTSDYAPGNDALTSFKEHFAAGGGEIVEEVKVPLANPDFA 209
Cdd:cd06344 103 TQHGFKYIFRN---IP-SDEDIArqlaRYAARQGYKRIVIYYDDDSYGKGLANAFEEEARELGITIVDRRSYSSDEEDFR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 210 PFLQR-MKDAKPDAMFVfvpAG---QGGNFMKQYAERGLDKAgikVIGpGDVMD-DDLLNGMGDAALGAVTAHIYSAAHP 284
Cdd:cd06344 179 RLLSKwKALDFFDAIFL---AGsmpEGAEFIKQARELGIKVP---IIG-GDGLDsPELIEIAGKAAEGVVVATVFDPDDP 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 285 SQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTgGKTDGDALVAAMKGMK-WESPRGPISIDPDTRDIVQNVY 363
Cdd:cd06344 252 RPEVRAFVEAFRKKYGREPDVWAAQGYDAVKLLAEAIEKA-GSTVPAKIASALRFLEnWEGVTGTYSFDANGDVVGKAIY 330
|
..
gi 639173078 364 IR 365
Cdd:cd06344 331 FK 332
|
|
| PBP1_YraM_LppC_lipoprotein-like |
cd06339 |
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup ... |
33-356 |
5.61e-24 |
|
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).
Pssm-ID: 380562 [Multi-domain] Cd Length: 331 Bit Score: 101.19 E-value: 5.61e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDTiagkKIEVILKDDAAlPDKTKTAAQELIvSEKVNAIAG--FGvtPAA 110
Cdd:cd06339 1 RIALLLPLSGPYAAAGQAIRDGIELALFDAGGS----RPELRVYDTGG-PEGAAAAYQQAV-AEGADLIIGplLK--SSV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITekSPYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEHFAA 190
Cdd:cd06339 73 AALAAAAQALGVPVLALNNDESATA--GPGLFQFGLSPEDEARQAARYAVQQGLRRFAVLAPDNAYGQRVANAFREAWQA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 191 GGGEIVEEVKVPLANPDFAPFLQRMKDA----------------------KPDAMFVFVPAGQGGNFMKQYAERGLDKag 248
Cdd:cd06339 151 LGGTVVAVESYDPDETDFSAAIRRLLGVdqsearirqlgellefeprrrqDFDAIFLPAGPEQARLIAPQLAFYGAGD-- 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 249 IKVIGPGDVMDDDLLNGMGDAALGAvtahIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLIYEALKKTGGKT 328
Cdd:cd06339 229 VPLLGTSLWYSGKLNLLRDPDLNGA----WFADPPWLLSPRAFPLRYRLAYGWPPPRLAALGYDAYRLAARLARLGGGLT 304
|
330 340
....*....|....*....|....*...
gi 639173078 329 DGDALVAAMkgmkwesprGPISIDPDTR 356
Cdd:cd06339 305 PGAGFSGLT---------GLLRLDPDGR 323
|
|
| PBP1_ABC_ligand_binding-like |
cd19982 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
33-317 |
3.59e-23 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380637 [Multi-domain] Cd Length: 302 Bit Score: 98.51 E-value: 3.59e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQ--HGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd19982 1 KIGAILSLTGPFAPFGEMFKNGYEMALEEinAAGGIKGKKLELVIEDDQSKPQTALAAAEKLVSQDKVPLIVGGYSSGIT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEK-SPYIVRTSFTLPQSSTIIGDWAVKNG-IKKVATLTSDYAPGNDALTSFKEHF 188
Cdd:cd19982 81 LPVAAVAERQKIPLLVPTAADDDITKPgYKYVFRLNPPASIYAKALFDFFKELVkPKTIAILYENTAFGTSVAKAARRFA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 189 AAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKAGIKVIGPGDVMdDDLLNGMGD 268
Cdd:cd19982 161 KKRGIEVVADESYDKGATDFKPLLNKVKAANPDVVYMVSYLNDAILLMRQAKELGLNPKLFAGGGAGFTI-PEFLKQAGP 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 639173078 269 AALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLI 317
Cdd:cd19982 240 LAEYVVTATLWSPDVKYPGAKEFYEKYKAKYGVEPSYHEAEAYAALYVA 288
|
|
| PBP1_ABC_HAAT-like |
cd19983 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-312 |
1.01e-22 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380638 [Multi-domain] Cd Length: 303 Bit Score: 97.27 E-value: 1.01e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIvSEKVNAIAGFGVTPAA 110
Cdd:cd19983 1 RIGFVGGLTGRYSDLGVQGRNGAQLAVEEINAAggINGRPVELIIRDDQQDPEAAKAADRELI-AGGVVAIIGHMTSAMT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLtsdYAPGNDA-----LTSF 184
Cdd:cd19983 80 VAVLPVINEAKVLMISPTVSTPELSGKDDYFFRVTPTTRESAQALARYAYNRgGLRRVAVI---YDLSNRAyseswLDNF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 185 KEHFAAGGGEIVEEVK-VPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQyaergLDKAGIKV--IGPGDVMDDD 261
Cdd:cd19983 157 RSEFEALGGRIVAEIPfSSGADVDFSDLARRLLASKPDGLLLVASAVDTAMLAQQ-----IRKLGSKIplFSSAWAATEE 231
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 639173078 262 LLNGMGDAALGAVTAHIYSAAHPSQANKDFVAAYKKAFGNRPGFMAVGGYD 312
Cdd:cd19983 232 LLELGGKAVEGMLFSQAYDRNSSNPRYLAFKEAYEERFGREPSFAAAYAYE 282
|
|
| PBP1_SBP-like |
cd19987 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
33-364 |
4.89e-22 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380642 [Multi-domain] Cd Length: 353 Bit Score: 96.24 E-value: 4.89e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTG-----------KQIDNA---IKLYMQQHGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKV 98
Cdd:cd19987 1 TIGLNVPLSGPYAPQGedqrrgfelavDHLNNGgglVDKDSRLSGDGILGKKVELVTADTETKADTAVDNAKRLIEQDGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 99 NAIAGFGVTPAALAAAPLATQGKIPEIVMAAGTSIITEK--SPYIVRTSFTLPQSSTIIGDWAVKN--GIKKVATLTSDY 174
Cdd:cd19987 81 VMITGGSSSAVAVAAQKLAQKEGVLYFAGLSHSNDTTGKdcHRYGFRECFNAHMSAKALAPYLVEKfgKDRKYFYLTADY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 175 APGNDALTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDaMFVFVPAGQGG-NFMKQYAERGLDKAgIKVIG 253
Cdd:cd19987 161 TWGHSTEQSMREYTEAHGWKTVGNPATPLGETDFSAALLNAADSGAD-VLVLVLFGRDMvNALKQAKQFGLLKK-MDIVV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 254 PgdvmddDLLNGMGDAALGAVTAHIYSAA--HPSQAN-----KDFVAAYKKAFGNRPGFMAVGGYdGIHLIYEALKKTGG 326
Cdd:cd19987 239 P------LLTAFMAESVGPEIMEGVLGTVnwHWSLPDdysyaFGKAEAFEKEYGAYPSQAAASAY-VQVLQYAAAVERAG 311
|
330 340 350
....*....|....*....|....*....|....*...
gi 639173078 327 KTDGDALVAAMKGMKWESPRGPISIDPDTRDIVQNVYI 364
Cdd:cd19987 312 SFDPPAVIRALEGHEYTLLKGEQYWRACDHQSVRPVYV 349
|
|
| PBP1_ABC_ligand_binding-like |
cd19978 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
32-367 |
4.62e-21 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380633 [Multi-domain] Cd Length: 341 Bit Score: 93.02 E-value: 4.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 32 FKIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPA 109
Cdd:cd19978 1 IRLGMSAALSGPAAELGNEMKRGIEAAFNEVNAQggVNGRKIKLIALDDGYEPDRTVKNTKKLIEEDKVFALIGYVGTPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 110 ALAAAPLATQGKIPEIVMAAGTSII-TEKSPYIV--RTSFTlPQSSTIIgDWAVKNG-IKKVATLTSDYAPGNDALTSFK 185
Cdd:cd19978 81 ALAALPLANEKKIPLFGPFTGAEFLrTPFLPYVFnlRASYA-DETEALV-DYLVKTLgPKRIAIFYQNDAFGLAGLEGAK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 186 EHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDK--AGIKVIGPgdvmdDDLL 263
Cdd:cd19978 159 KALKKRGLTPVAEGSYTRNTLDVEEALAKILKAKPEAIILVGTYAPAAEFIRLARAAGLNPlfANVSFVGS-----EALA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 264 NGMGDAALGAVtaHIYSAAHPSQANKDFVAAYKKAFGN-----RPGFMAVGGYDGIHLIYEALKKTGGKTDGDALVAAMK 338
Cdd:cd19978 234 LELGDYGEGVI--VSQVVPDPNDSSLPIVKEYREAMKKygpnaPPDFVSLEGYLAARLLVEALKKAGPPLTREKLLALEE 311
|
330 340 350
....*....|....*....|....*....|
gi 639173078 339 GMKWES-PRGPISIDPDTRDIVQNVYIRKV 367
Cdd:cd19978 312 SLKNDLgKGLTLTFSPNDHQGSDKVWLTTL 341
|
|
| PBP1_ABC_HAAT-like |
cd19985 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
33-317 |
2.32e-17 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380640 [Multi-domain] Cd Length: 321 Bit Score: 81.94 E-value: 2.32e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQ---HGDtIAGKKIEVILKDDAALPDKTKTAAQElIVSEKVNAIAGFGVTPA 109
Cdd:cd19985 1 HIAVVGPMSGKSASKGKSMLRGAELYIDQinaAGG-INGKKVKLDVFDDQNDPDAARKAAQI-IVSDKALAVIGHYYSSA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 110 ALAAAPLATQGKIPEIVMAAGTSIITEKSPYIVRTSFTLPQSSTIIGDWAVKN-GIKKVATLTSDYAPGNDALTSFKEHF 188
Cdd:cd19985 79 SIAAGKIYKKAGIPAITPSATADAVTRDNPWYFRVIFNDSLQGRFLANYAKKVlKKDKVSIIYEEDSYGKSLASVFEATA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 189 AAGGGEIVEEVKVPLANPDFAPFLQRMKDA------KPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGDVMDDDL 262
Cdd:cd19985 159 RALGLKVLKKWSFDTDSSQLDQNLDQIVDElkkapdEPGVIFLATHADEGAKLIKKLRDAGLK---APIIGPDSLASESF 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639173078 263 LNGMGD-----AALGAVTAHIYSAAH-----PSQANKDFVAAYKKAFGNRPGFMAVGGYDGIHLI 317
Cdd:cd19985 236 AQGFAEypeekEEPGYYTDGIYATSPfifdiANEKAQKFRDTYQKRYGEEPSWIAAFAYDAAMLA 300
|
|
| PBP1_ABC_ligand_binding-like |
cd19979 |
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes ... |
33-336 |
2.17e-16 |
|
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380634 [Multi-domain] Cd Length: 350 Bit Score: 79.58 E-value: 2.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQQHGDT--IAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPAA 110
Cdd:cd19979 1 VIGLDADLSGGSAASGEAIKRGIQLAIDEINAAggLLGRKLELVAKDHRGNPARGVDNLREFAADPDVLAVFGGLHSPVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 111 LAAAPLATQGKIPEIV-MAAGTSII-TEKSP-YIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEH 187
Cdd:cd19979 81 LAELDFIHELKIPYLVpWAAATPITrNGYSPnYIFRLSVDDSLAGPFLVEYALKKGCKRPALLLENTGWGRSNLKAMTKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 188 FAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGldkAGIKVI---GP-GDvmDDDLL 263
Cdd:cd19979 161 LAKKGLQPVGVEWFNWGDTDAKPQLRALKAAGADAILLVANAPEGAAIVKALAALP---ERLPIIshwGItGG--DFPEL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 264 NGMGDAALGAVTAHIYSAAHPSQ--ANKDFVAAYKKAFGNRPG----FMAVG---GYDGIHLIYEALKKTGGkTDGDALV 334
Cdd:cd19979 236 PREALSKIDLRFIQTFSFFDANQspRGKQVLARYKRRYPVEDPesdiPAPVGfahAYDLTHLLALAIEQAGS-TDRAAVR 314
|
..
gi 639173078 335 AA 336
Cdd:cd19979 315 AA 316
|
|
| PBP1_ABC_ligand_binding-like |
cd06334 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
33-354 |
1.46e-15 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380557 [Multi-domain] Cd Length: 360 Bit Score: 77.28 E-value: 1.46e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQIDNAIKLYMQ---QHGDtIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPA 109
Cdd:cd06334 1 KIGLLTDLTGPTADVGKPYAQGVRDYLNyvnEEGG-INGVKIELEECDTGYKVPRAVACYKRLKAQDGVVAILGWGTGDT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 110 ALAAAPLAtQGKIPeiVMAAGTS----IITEKSPYIvrtsFTLPQSST---------IIGDWAVKNGIKKVATLTSDYAP 176
Cdd:cd06334 80 EALAPRVA-KDKIP--YISASYGrslaDDGKVFPYN----FFVGATYSsqarallkyIAQEWGGKLKGPKVAFVYHDSPF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 177 GNDALTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDkagIKVIGPGD 256
Cdd:cd06334 153 GREPIPALKAYAKELGFEVVAEQVPSPGALDATAQWLRIRRAGPDYVIIQGTGGSVAVIIKDAKRLGLK---TKFIGNIW 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 257 VMDDDLLNGMGDAALGAVTAHIYSAAHPSQANKDFVAAYKKAfGNRPGFMAVG--GY-DGIHLIY-------EALKKTGG 326
Cdd:cd06334 230 GGDEDLIKLAGDAAEGYVGVSPFAFGTDDPPGKEIVEEVAKK-GKGDGPEEVGtvYYnRGWATAMlaveairRADKAGGG 308
|
330 340 350
....*....|....*....|....*....|.
gi 639173078 327 KTDGDALVAAMKGMKWESPRG---PISIDPD 354
Cdd:cd06334 309 TGLGNKLKAGLERLKDFDLGGlapPVTFTPT 339
|
|
| PBP1_ABC_ligand_binding-like |
cd06337 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
33-349 |
1.35e-13 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380560 [Multi-domain] Cd Length: 354 Bit Score: 71.18 E-value: 1.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQ---IDNAIKLYMQQHGDTIAGKK--IEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVT 107
Cdd:cd06337 1 KIGRVSPLTGPLAAFGEAdpwVLEQIREAFADGGIKVGGKKypVEIVVRDSQSDPNRAGEAARDLILRDKVDLMLASGTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 108 PAALAAAPLATQGKIP--------EIVMAAGTSIITEKSPYIVRTSFTLPQ-SSTIIGDWAVKNGIKKVATLTSDYAPGN 178
Cdd:cd06337 81 DTVNPVADQCEANGVPcistdapwQAWFFGRGGDPAKGFKWTFHFFWGLEDiAANFLGMWDQVPTNKVVGLLWPNDPDGT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 179 DALTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLdKAGIKVIGPGDVM 258
Cdd:cd06337 161 AFADAFLGLPAAAGYTLVDPGRFPPGTDDFSSIINAFKKAGVEIVTGVMIPPDFATFWRQAAQQGF-KPKVVTIGKALLF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 259 DDDlLNGMGDAALGAVTAHIYSAAHP------SQANKDFVAAYKKAFGnRPGFMAVGGYdgiHLIYEAL---KKTGGKTD 329
Cdd:cd06337 240 PSA-VAALGDLGDGLSTEVWWSPAHPfkssltGQTAAELADAYEKATG-KQWTQPLGYA---HALFEVAvdaLKRAGSPD 314
|
330 340
....*....|....*....|
gi 639173078 330 GDALVAAMKGMKWESPRGPI 349
Cdd:cd06337 315 DEAVRAALADTDLDTIVGPV 334
|
|
| PRK15404 |
PRK15404 |
high-affinity branched-chain amino acid ABC transporter substrate-binding protein; |
6-387 |
9.42e-13 |
|
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
Pssm-ID: 237959 [Multi-domain] Cd Length: 369 Bit Score: 68.89 E-value: 9.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 6 RKLSRWMLGAIAvgtLALAPARAEDSFKIGLILPMTGGQASTGKQIDN----AIKLYMQQHGdtIAGKKIEVILKDDAAL 81
Cdd:PRK15404 3 SKGKTLLAGCIA---LALSHAALADDIKIAIVGPMSGPVAQYGDMEFTgarqAIEDINAKGG--IKGDKLEGVEYDDACD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 82 PdKTKTAAQELIVSEKVNAIAGFGVTPAALAAAPLATQGKIPEIVMAAGTSIITEKSP-YIVRT----SFTLPQSSTIIG 156
Cdd:PRK15404 78 P-KQAVAVANKVVNDGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYqLIFRTigldSDQGPTAAKYIL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 157 DwAVKNgiKKVATLTSDYAPGNDALTSFKEHFAAGGGEIVEEVKVPLANPDFAPFLQRMKDAKPDamfvFVPAG----QG 232
Cdd:PRK15404 157 E-KVKP--KRIAVLHDKQQYGEGLARSVKDGLKKAGANVVFFEGITAGDKDFSALIAKLKKENVD----FVYYGgyhpEM 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 233 GNFMKQYAERGLDkagIKVIGPGDVMDDDLLNGMGDAALGA-VTAHIYSAAHPsqANKDFVAAYKKAFGNRPGFMAVGGY 311
Cdd:PRK15404 230 GQILRQAREAGLK---TQFMGPEGVGNKSLSNIAGPASEGMlVTLPKRYDQDP--ANKAIVDAFKAKKQDPSGPFVWTTY 304
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639173078 312 DGIHLIYEALKKTGGkTDGDALVAAMKGMKWESPRGPISIDPdtrdivqnvyirkvgkvDGELYNVEFETFEAVKD 387
Cdd:PRK15404 305 AAVQSLAAGINRAGS-DDPAKVAKYLKANTFDTVIGPLSWDE-----------------KGDLKGFEFGVFEWHAD 362
|
|
| ANF_receptor |
pfam01094 |
Receptor family ligand binding region; This family includes extracellular ligand binding ... |
50-354 |
2.37e-08 |
|
Receptor family ligand binding region; This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.
Pssm-ID: 460062 [Multi-domain] Cd Length: 347 Bit Score: 55.08 E-value: 2.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 50 QIDNAIKLYMQQH---GDTIAGKKIEVILKDDAALPDKTKTAAQELIvSEKVNAIAGFGVTPAALAAAPLATQGKIPEIV 126
Cdd:pfam01094 1 LVLLAVRLAVEDInadPGLLPGTKLEYIILDTCCDPSLALAAALDLL-KGEVVAIIGPSCSSVASAVASLANEWKVPLIS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 127 MAAGTSIITEKS--PYIVRTSF-TLPQSSTIIGdwAVKN-GIKKVATLTSDYAPGNDALTSFKEHFAAGGGEIVEEVKVP 202
Cdd:pfam01094 80 YGSTSPALSDLNryPTFLRTTPsDTSQADAIVD--ILKHfGWKRVALIYSDDDYGESGLQALEDALRERGIRVAYKAVIP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 203 LANPD---FAPFLQRMKDaKPDAMFVFVPAGQGGNFMKQYAERGLDKAGIKVIG-----PGDVMDDDLLNGMGDAALGAV 274
Cdd:pfam01094 158 PAQDDdeiARKLLKEVKS-RARVIVVCCSSETARRLLKAARELGMMGEGYVWIAtdgltTSLVILNPSTLEAAGGVLGFR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 275 TAHIYSAAHPSQANKDFvAAYKKAFGNRPGFM---AVGGYDGIHLIYEALKKTGGKT-------------DGDALVAAMK 338
Cdd:pfam01094 237 LHPPDSPEFSEFFWEKL-SDEKELYENLGGLPvsyGALAYDAVYLLAHALHNLLRDDkpgracgalgpwnGGQKLLRYLK 315
|
330
....*....|....*.
gi 639173078 339 GMKWESPRGPISIDPD 354
Cdd:pfam01094 316 NVNFTGLTGNVQFDEN 331
|
|
| PBP1_glutamate_receptors-like |
cd06269 |
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl ... |
33-278 |
3.01e-07 |
|
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as natriuretic peptide receptors (NPRs), and N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of ionotropic glutamate rece; This CD represents the ligand-binding domain of the family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs), and the N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the ionotropic glutamate receptors, all of which are structurally similar and related to the periplasmic-binding fold type 1 family. The family C GPCRs consists of metabotropic glutamate receptor (mGluR), a calcium-sensing receptor (CaSR), gamma-aminobutyric acid receptor (GABAbR), the promiscuous L-alpha-amino acid receptor GPR6A, families of taste and pheromone receptors, and orphan receptors. Truncated splicing variants of the orphan receptors are not included in this CD. The family C GPCRs are activated by endogenous agonists such as amino acids, ions, and sugar based molecules. Their amino terminal ligand-binding region is homologous to the bacterial leucine-isoleucine-valine binding protein (LIVBP) and a leucine binding protein (LBP). The ionotropic glutamate receptors (iGluRs) have an integral ion channel and are subdivided into three major groups based on their pharmacology and structural similarities: NMDA receptors, AMPA receptors, and kainate receptors. The family of membrane bound guanylyl cyclases is further divided into three subfamilies: the ANP receptor (GC-A)/C-type natriuretic peptide receptor (GC-B), the heat-stable enterotoxin receptor (GC-C)/sensory organ specific membrane GCs such as retinal receptors (GC-E, GC-F), and olfactory receptors (GC-D and GC-G).
Pssm-ID: 380493 [Multi-domain] Cd Length: 332 Bit Score: 51.65 E-value: 3.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQAStGKQIDNAIKLYMQQ---HGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVTPA 109
Cdd:cd06269 1 TIGALLPVHDYLES-GAKVLPAFELALSDvnsRPDLLPKTTLGLAIRDSECNPTQALLSACDLLAAAKVVAILGPGCSAS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 110 ALAAAPLATQGKIPEIVMAAGTSIITEKS--PYIVRT----SFTLPQSSTIIGDWavknGIKKVATLTSDYAPGNDALTS 183
Cdd:cd06269 80 AAPVANLARHWDIPVLSYGATAPGLSDKSryAYFLRTvppdSKQADAMLALVRRL----GWNKVVLIYSDDEYGEFGLEG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 184 FKEHFAAGGGEIVEEVKVPLANP-DFAPFLQRMKDAKPDAMFVFVPAGQGGNFMKQYAERGLDKAGIKVIGPGDVMDDDl 262
Cdd:cd06269 156 LEELFQEKGGLITSRQSFDENKDdDLTKLLRNLRDTEARVIILLASPDTARSLMLEAKRLDMTSKDYVWFVIDGEASSS- 234
|
250
....*....|....*.
gi 639173078 263 lNGMGDAALGAVTAHI 278
Cdd:cd06269 235 -DEHGDEARQAAEGAI 249
|
|
| PBP1_NPR_GC-like |
cd06352 |
ligand-binding domain of membrane guanylyl-cyclase receptors; Ligand-binding domain of ... |
33-357 |
7.03e-04 |
|
ligand-binding domain of membrane guanylyl-cyclase receptors; Ligand-binding domain of membrane guanylyl-cyclase receptors. Membrane guanylyl cyclases (GC) have a single membrane-spanning region and are activated by endogenous and exogenous peptides. This family can be divided into three major subfamilies: the natriuretic peptide receptors (NPRs), sensory organ-specific membrane GCs, and the enterotoxin/guanylin receptors. The binding of peptide ligands to the receptor results in the activation of the cytosolic catalytic domain. Three types of NPRs have been cloned from mammalian tissues: NPR-A/GC-A, NPR-B/ GC-B, and NPR-C. In addition, two of the GCs, GC-D and GC-G, appear to be pseudogenes in humans. Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are produced in the heart, and both bind to the NPR-A. NPR-C, also termed the clearance receptor, binds each of the natriuretic peptides and can alter circulating levels of these peptides. The ligand binding domain of the NPRs exhibits strong structural similarity to the type 1 periplasmic binding fold protein family.
Pssm-ID: 380575 [Multi-domain] Cd Length: 391 Bit Score: 41.57 E-value: 7.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 33 KIGLILPMTGGQASTGKQ-----IDNAIKLyMQQHGDTIAGKKIEVILKDDAALPDKTKTAAQELIVSEKVNAIAGFGVT 107
Cdd:cd06352 1 KVGVLAPSNSQSLPVGYArsapaIDIAIER-INSEGLLLPGFNFEFTYRDSCCDESEAVGAAADLIYKRNVDVFIGPACS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 108 PAALAAAPLATQGKIPEIVMAAGTSIITEKS--PYIVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPG-NDALTSF 184
Cdd:cd06352 80 AAADAVGRLATYWNIPIITWGAVSASFLDKSryPTLTRTSPNSLSLAEALLALLKQFNWKRAAIIYSDDDSKcFSIANDL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 185 KEHFAAGGGEIV--EEVKVPLANPDFAPFLQRMKDAkpdA--MFVFVPAGQGGNFMKQYAERG------------LDKAG 248
Cdd:cd06352 160 EDALNQEDNLTIsyYEFVEVNSDSDYSSILQEAKKR---AriIVLCFDSETVRQFMLAAHDLGmtngeyvfifieLFKDG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 249 IKVIGPGDVMDDDLLNgmgDAALGAVTAHIYSAAHP--SQANKDFVAAYKKAFGNRPGFMAVGG-----------YDGIH 315
Cdd:cd06352 237 FGGNSTDGWERNDGRD---EDAKQAYESLLVISLSRpsNPEYDNFSKEVKARAKEPPFYCYDASeeevspyaaalYDAVY 313
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 639173078 316 LIYEALKKT----GGKTDGDALVAAMKGMKWESPRGPISIDPD-TRD 357
Cdd:cd06352 314 LYALALNETlaegGNYRNGTAIAQRMWNRTFQGITGPVTIDSNgDRD 360
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| PBP1_ABC_transporter_GPCR_C-like |
cd04509 |
Family C of G-protein coupled receptors and their close homologs, the type 1 ... |
122-275 |
4.05e-03 |
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Family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems; This CD includes members of the family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems. The family C GPCR includes glutamate/glycine-gated ion channels such as the NMDA receptor, G-protein-coupled receptors, metabotropic glutamate, GABA-B, calcium sensing, pheromone receptors, and atrial natriuretic peptide-guanylate cyclase receptors. The glutamate receptors that form cation-selective ion channels, iGluR, can be classified into three different subgroups according to their binding-affinity for the agonists NMDA (N-methyl-D-asparate), AMPA (alpha-amino-3-dihydro-5-methyl-3-oxo-4-isoxazolepropionic acid), and kainate. L-glutamate is a major neurotransmitter in the brain of vertebrates and acts through either mGluRs or iGluRs. mGluRs subunits possess seven transmembrane segments and a large N-terminal extracellular domain. ABC-type leucine-isoleucine-valine binding protein (LIVBP) is a bacterial periplasmic binding protein that has homology with the amino-terminal domain of the glutamate-receptor ion channels (iGluRs). The extracellular regions of iGluRs are made of two PBP-like domains in tandem, a LIVBP-like domain that constitutes the N terminus (included in this model) followed by a domain related to lysine-arginine-ornithine-binding protein (LAOBP) that belongs to the type 2 periplasmic binding fold protein superfamily. The uncharacterized periplasmic components of various ABC-type transport systems are also included in this family.
Pssm-ID: 380490 Cd Length: 306 Bit Score: 38.83 E-value: 4.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 122 IPEIVMAAGTSIITEKSPY--IVRTSFTLPQSSTIIGDWAVKNGIKKVATLTSDYAPGNDALTSFKEHFAAGGGEIVEEV 199
Cdd:cd04509 125 IPQITYAATAPELSDDRGYqlFLRVVPLDSDQAPAMADIVKEKVWQYVSIVHDEGQYGEGGARAFQDGLKKGGLCIAFSD 204
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639173078 200 KVPL--ANPDFAPFLQRMKDaKPDAMFVFVpaGQGGNFMKQY--AERGLDKAG-IKVIGPGDVMDDDL-LNGMGDAALGA 273
Cdd:cd04509 205 GITAgeKTKDFDRLVARLKK-ENNIRFVVY--FGYHPEMGQIlrAARRAGLVGkFQFMGSDGWANVSLsLNIAEESAEGL 281
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..
gi 639173078 274 VT 275
Cdd:cd04509 282 IT 283
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