|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
310-834 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 800.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 310 SCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRC 389
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 390 SFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPirANSRQRVLKSLYK--TYVDVVHVK 467
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP--YGFKLNTVKGLPVfaTYIEANHVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 468 KVSDKRLDVDTSTIeqelmqnkvdhneveeVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGG 547
Cdd:smart00350 159 KLDYKRSFEDSSFS----------------VQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGG 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 548 TNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGG 627
Cdd:smart00350 223 VHKNLPDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNG 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 628 VCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYL 707
Cdd:smart00350 303 VCCIDEFDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFV 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 708 VLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDV-LPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRS 786
Cdd:smart00350 383 VLDEVDEERDRELAKHVVDLHRYSHPEEDEAFEPpLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTES 462
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 6325276 787 dEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIK 834
Cdd:smart00350 463 -RSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
207-913 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 641.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 207 KILDEREEFInnttdEELYYIKQLNEMRE--LGTSNLNLDARNLLAYKqtEDLYHQLLNYPQEVISIMDQTIKDcmvsli 284
Cdd:COG1241 4 DLVDKFEEFL-----RRYKYRDEILELAQeyPEKRSLVVDYNDLYSFD--PDLADDLLENPDEVLEAAEEALRE------ 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 285 vdnnldYDLDEIETKFYK--VRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDR 362
Cdd:COG1241 71 ------IDLEPYDVSLGDahVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTG 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 363 GVIQEPARCERidCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSI 442
Cdd:COG1241 145 EKLQEPHECPG--CGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 443 PIRansRQRVLKSLYKTYVDVVHVKkVSDKrldvdtstieqelmqnkvdhnEVEEVrQITDQDLAKIREVAAREDLYSLL 522
Cdd:COG1241 223 QRT---SGRGKSTIFDLYLEANSIE-VEEK---------------------EFEEI-EITEEDEEKIKELSKDPDIYEKI 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 523 ARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLT 602
Cdd:COG1241 277 IASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLT 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 603 AYITRD-VDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSR 681
Cdd:COG1241 357 AAAVRDdFGTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGR 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 682 YNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNL---------YLEDKPEHIsqDDVLPVEFLTMYIS 752
Cdd:COG1241 437 FDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVhragelleqEIEEETEEV--KPEIDPDLLRKYIA 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 753 YAKEHIHPIITEAAKTELVRAYVGMRKMGDDsrsDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSA 832
Cdd:COG1241 515 YARRNVFPVLTEEAKDLIEDFYVDMRKKGED---EDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSC 591
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 833 IKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLsREIMNVLKDQASDSMSFNELIKqinEHSQDRVESSDIQEALSRLQQ 912
Cdd:COG1241 592 LKDVGVDPETGKFDIDVIETGTSKSQRDKMKLI-KDIIKELEEESSGGAPIEDVIE---EAEEEGIDREKAEELIEKLKR 667
|
.
gi 6325276 913 E 913
Cdd:COG1241 668 K 668
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
210-913 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 610.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 210 DEREEFINNTTDEE--LYYIKQLNEMRELGTSNLNLDARNLLAYKQteDLYHQLLNYPQEVISIMDQTIKDCMVSLivdn 287
Cdd:NF040949 3 EKFKEFIRTFRDSFgnEKYKERIFEMIAMRKRSLVVDFNDLYMFDP--ELADLLIEKPDEVLPAASKALKEIVEEE---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 288 nlDYDLDEIETKFYkVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAV----EIDRG 363
Cdd:NF040949 77 --DPEYAEEVAKFH-VRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWpeeeEESYE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 364 VIQEPARCERidCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIP 443
Cdd:NF040949 154 IVEPPTVCPV--CGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKP 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 444 IRANSRQRvlKSLYKTYVDVVHVKkVSDKrldvdtstieqelmqnkvdhnEVEEVrQITDQDLAKIREVAAREDLYSLLA 523
Cdd:NF040949 232 DSSLKKGS--RPIFKNYIEANHIE-VSQK---------------------ELEEV-EITEEDEEKILELAKDPWIREKII 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 524 RSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTA 603
Cdd:NF040949 287 ASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTA 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 604 YITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYN 683
Cdd:NF040949 367 AVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYD 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 684 PNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYledkPEHISQDDVLPVEFLTMYISYAKEHIHPIIT 763
Cdd:NF040949 447 PNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVH----SGKEKVKPEIDPDLLKKYIAYARKYVRPKLT 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 764 EAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTG 843
Cdd:NF040949 523 EEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIDVETG 602
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6325276 844 KIDMNLVQTGKSVIQRklqeDLSREIMNVLKDQASDS--MSFNELIKQINEHSqdrVESSDIQEALSRLQQE 913
Cdd:NF040949 603 KIDIDTIMTGKPKSKR----EKMSKIVEIIKELEEEEecVKIKELIKEAEKKG---IDEEKVEELISDLKRS 667
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
521-832 |
0e+00 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 596.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 521 LLARSIAPSIYELEDVKKGILLQLFGGTNKTFTK-GGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAV 599
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 600 GLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIG 679
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 680 SRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHIsQDDVLPVEFLTMYISYAKEHIH 759
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHI-QDEVLDVEVLTDYISYAREHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6325276 760 PIITEAAKTELVRAYVGMRKMGDDSRsdeKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSA 832
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKMGSDAR---KRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
187-925 |
1.15e-162 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 499.91 E-value: 1.15e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 187 IQECTTNFRNFLMSFKyKFRKILDEREEFINNTTDEELYY-IKQLNEMRElgtsNLNLDARNLLAYKQTE---------- 255
Cdd:PTZ00111 85 LEELSERFTNFLKNFT-EFSDVLEFKDEQQSKPEYTELYYlWKLMNFIKE----NLRDHSTGYSRILPFEvdlmhvysfd 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 256 -DLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEiETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLR 334
Cdd:PTZ00111 160 kVLYKLLVTFPADCIAELDKVLVKLFNELLSKHYSDLSLEN-NSFFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVR 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 335 STPVIPDMKVAFFKC-----------NVCDHTMAVEIDRGVIQEPARCEriDCNEPNSMSLIHNRCSFADKQVIKLQETP 403
Cdd:PTZ00111 239 QTWIVPEITMACFRCrgqkkiglndyQPCTCEHYEYVIQGEVNEPLLCN--ECNSKYTFELNHNMCVYSTKKIVKLLQSN 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 404 DFVPDGQTP--------------------HSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDV 463
Cdd:PTZ00111 317 SSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIRTSTTRRTLKSLYTYFVNV 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 464 VHVKKVsdKRLDVDTSTIEQELMQNKVDhneveevrqITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQ 543
Cdd:PTZ00111 397 IHVKVI--NSTNANQPEKGLKYLGNEND---------FSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQ 465
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 544 LFGG------TNKTFT---KGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYIT-RDVDTKQ 613
Cdd:PTZ00111 466 LFSGnknssdFNKSPDacyKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGR 545
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 614 LVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENID 693
Cdd:PTZ00111 546 AMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENIN 625
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 694 LPPPLLSRFDLVYLVLDKVDEKNDRELA---------KHLTNL------YLEDKPEHISQDDVLP--------VEFLTMY 750
Cdd:PTZ00111 626 ISPSLFTRFDLIYLVLDHIDQDTDQLISlsiakdfllPHMTGSgndedtYDRSNTMHVEDESLRSekdynkndLDMLRMY 705
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 751 ISYAKEHIHPIITEAAKTELVRAYVGMRKMG---------DDSRSDE-----------KRITATTRQLESMIRLAEAHAK 810
Cdd:PTZ00111 706 IKFSKLHCFPKLSDEAKKVITREYVKMRQGNfqtsnldelEHAQEDDdddlyyqssgtRMIYVSSRMISSIIRISVSLAR 785
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 811 MKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVL----KDQASDSMSFNEL 886
Cdd:PTZ00111 786 MRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQMYEQVLSVLtrssNQDSNKSLDLNEV 865
|
810 820 830 840
....*....|....*....|....*....|....*....|....*
gi 6325276 887 IKQINEHSQDRVESSD------IQEALSRLQQEDKVIVLGEGVRR 925
Cdd:PTZ00111 866 LSLCHKTFKDNRDHKDgeiyklISEVLNKMVQEGTAVRENNSYYL 910
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
505-728 |
4.80e-141 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 418.86 E-value: 4.80e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 505 DLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKI 584
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 585 TPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITT 664
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6325276 665 LNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLY 728
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
194-307 |
1.27e-15 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 73.09 E-value: 1.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 194 FRNFLMSFKykfrkildereefinNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYKqtEDLYHQLLNYPQEVISIMD 273
Cdd:pfam14551 4 FKDFLEEFR---------------EDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFD--PDLAEALLENPYEYLPLFE 66
|
90 100 110
....*....|....*....|....*....|....
gi 6325276 274 QTIKDCMVSLIVDNNldydlDEIETKFYKVRPYN 307
Cdd:pfam14551 67 EALKEVVKELSEDPD-----YAEEEKEFQVRFYN 95
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
310-834 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 800.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 310 SCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRC 389
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 390 SFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPirANSRQRVLKSLYK--TYVDVVHVK 467
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP--YGFKLNTVKGLPVfaTYIEANHVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 468 KVSDKRLDVDTSTIeqelmqnkvdhneveeVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGG 547
Cdd:smart00350 159 KLDYKRSFEDSSFS----------------VQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGG 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 548 TNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGG 627
Cdd:smart00350 223 VHKNLPDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNG 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 628 VCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYL 707
Cdd:smart00350 303 VCCIDEFDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFV 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 708 VLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDV-LPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRS 786
Cdd:smart00350 383 VLDEVDEERDRELAKHVVDLHRYSHPEEDEAFEPpLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTES 462
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 6325276 787 dEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIK 834
Cdd:smart00350 463 -RSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
207-913 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 641.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 207 KILDEREEFInnttdEELYYIKQLNEMRE--LGTSNLNLDARNLLAYKqtEDLYHQLLNYPQEVISIMDQTIKDcmvsli 284
Cdd:COG1241 4 DLVDKFEEFL-----RRYKYRDEILELAQeyPEKRSLVVDYNDLYSFD--PDLADDLLENPDEVLEAAEEALRE------ 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 285 vdnnldYDLDEIETKFYK--VRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDR 362
Cdd:COG1241 71 ------IDLEPYDVSLGDahVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTG 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 363 GVIQEPARCERidCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSI 442
Cdd:COG1241 145 EKLQEPHECPG--CGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 443 PIRansRQRVLKSLYKTYVDVVHVKkVSDKrldvdtstieqelmqnkvdhnEVEEVrQITDQDLAKIREVAAREDLYSLL 522
Cdd:COG1241 223 QRT---SGRGKSTIFDLYLEANSIE-VEEK---------------------EFEEI-EITEEDEEKIKELSKDPDIYEKI 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 523 ARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLT 602
Cdd:COG1241 277 IASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLT 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 603 AYITRD-VDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSR 681
Cdd:COG1241 357 AAAVRDdFGTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGR 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 682 YNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNL---------YLEDKPEHIsqDDVLPVEFLTMYIS 752
Cdd:COG1241 437 FDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVhragelleqEIEEETEEV--KPEIDPDLLRKYIA 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 753 YAKEHIHPIITEAAKTELVRAYVGMRKMGDDsrsDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSA 832
Cdd:COG1241 515 YARRNVFPVLTEEAKDLIEDFYVDMRKKGED---EDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSC 591
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 833 IKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLsREIMNVLKDQASDSMSFNELIKqinEHSQDRVESSDIQEALSRLQQ 912
Cdd:COG1241 592 LKDVGVDPETGKFDIDVIETGTSKSQRDKMKLI-KDIIKELEEESSGGAPIEDVIE---EAEEEGIDREKAEELIEKLKR 667
|
.
gi 6325276 913 E 913
Cdd:COG1241 668 K 668
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
210-913 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 610.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 210 DEREEFINNTTDEE--LYYIKQLNEMRELGTSNLNLDARNLLAYKQteDLYHQLLNYPQEVISIMDQTIKDCMVSLivdn 287
Cdd:NF040949 3 EKFKEFIRTFRDSFgnEKYKERIFEMIAMRKRSLVVDFNDLYMFDP--ELADLLIEKPDEVLPAASKALKEIVEEE---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 288 nlDYDLDEIETKFYkVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAV----EIDRG 363
Cdd:NF040949 77 --DPEYAEEVAKFH-VRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWpeeeEESYE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 364 VIQEPARCERidCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIP 443
Cdd:NF040949 154 IVEPPTVCPV--CGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKP 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 444 IRANSRQRvlKSLYKTYVDVVHVKkVSDKrldvdtstieqelmqnkvdhnEVEEVrQITDQDLAKIREVAAREDLYSLLA 523
Cdd:NF040949 232 DSSLKKGS--RPIFKNYIEANHIE-VSQK---------------------ELEEV-EITEEDEEKILELAKDPWIREKII 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 524 RSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTA 603
Cdd:NF040949 287 ASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTA 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 604 YITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYN 683
Cdd:NF040949 367 AVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYD 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 684 PNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYledkPEHISQDDVLPVEFLTMYISYAKEHIHPIIT 763
Cdd:NF040949 447 PNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVH----SGKEKVKPEIDPDLLKKYIAYARKYVRPKLT 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 764 EAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTG 843
Cdd:NF040949 523 EEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIDVETG 602
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6325276 844 KIDMNLVQTGKSVIQRklqeDLSREIMNVLKDQASDS--MSFNELIKQINEHSqdrVESSDIQEALSRLQQE 913
Cdd:NF040949 603 KIDIDTIMTGKPKSKR----EKMSKIVEIIKELEEEEecVKIKELIKEAEKKG---IDEEKVEELISDLKRS 667
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
521-832 |
0e+00 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 596.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 521 LLARSIAPSIYELEDVKKGILLQLFGGTNKTFTK-GGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAV 599
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 600 GLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIG 679
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 680 SRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHIsQDDVLPVEFLTMYISYAKEHIH 759
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHI-QDEVLDVEVLTDYISYAREHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6325276 760 PIITEAAKTELVRAYVGMRKMGDDSRsdeKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSA 832
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKMGSDAR---KRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
521-832 |
2.30e-167 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 489.93 E-value: 2.30e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 521 LLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG 600
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 601 LTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGS 680
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 681 RYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPE----HISQDDVLPVEFLTMYISYAKe 756
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEeqvkPEEDGIPIDIELLRKYILYAR- 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6325276 757 HIHPIITEAAKTELVRAYVGMRKMGDDSRSdekrITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSA 832
Cdd:cd17706 240 QIHPKISEEAREKLVRWYVELRKESERRST----IPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
187-925 |
1.15e-162 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 499.91 E-value: 1.15e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 187 IQECTTNFRNFLMSFKyKFRKILDEREEFINNTTDEELYY-IKQLNEMRElgtsNLNLDARNLLAYKQTE---------- 255
Cdd:PTZ00111 85 LEELSERFTNFLKNFT-EFSDVLEFKDEQQSKPEYTELYYlWKLMNFIKE----NLRDHSTGYSRILPFEvdlmhvysfd 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 256 -DLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEiETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLR 334
Cdd:PTZ00111 160 kVLYKLLVTFPADCIAELDKVLVKLFNELLSKHYSDLSLEN-NSFFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVR 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 335 STPVIPDMKVAFFKC-----------NVCDHTMAVEIDRGVIQEPARCEriDCNEPNSMSLIHNRCSFADKQVIKLQETP 403
Cdd:PTZ00111 239 QTWIVPEITMACFRCrgqkkiglndyQPCTCEHYEYVIQGEVNEPLLCN--ECNSKYTFELNHNMCVYSTKKIVKLLQSN 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 404 DFVPDGQTP--------------------HSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDV 463
Cdd:PTZ00111 317 SSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIRTSTTRRTLKSLYTYFVNV 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 464 VHVKKVsdKRLDVDTSTIEQELMQNKVDhneveevrqITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQ 543
Cdd:PTZ00111 397 IHVKVI--NSTNANQPEKGLKYLGNEND---------FSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQ 465
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 544 LFGG------TNKTFT---KGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYIT-RDVDTKQ 613
Cdd:PTZ00111 466 LFSGnknssdFNKSPDacyKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGR 545
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 614 LVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENID 693
Cdd:PTZ00111 546 AMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENIN 625
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 694 LPPPLLSRFDLVYLVLDKVDEKNDRELA---------KHLTNL------YLEDKPEHISQDDVLP--------VEFLTMY 750
Cdd:PTZ00111 626 ISPSLFTRFDLIYLVLDHIDQDTDQLISlsiakdfllPHMTGSgndedtYDRSNTMHVEDESLRSekdynkndLDMLRMY 705
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 751 ISYAKEHIHPIITEAAKTELVRAYVGMRKMG---------DDSRSDE-----------KRITATTRQLESMIRLAEAHAK 810
Cdd:PTZ00111 706 IKFSKLHCFPKLSDEAKKVITREYVKMRQGNfqtsnldelEHAQEDDdddlyyqssgtRMIYVSSRMISSIIRISVSLAR 785
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 811 MKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVL----KDQASDSMSFNEL 886
Cdd:PTZ00111 786 MRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQMYEQVLSVLtrssNQDSNKSLDLNEV 865
|
810 820 830 840
....*....|....*....|....*....|....*....|....*
gi 6325276 887 IKQINEHSQDRVESSD------IQEALSRLQQEDKVIVLGEGVRR 925
Cdd:PTZ00111 866 LSLCHKTFKDNRDHKDgeiyklISEVLNKMVQEGTAVRENNSYYL 910
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
505-728 |
4.80e-141 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 418.86 E-value: 4.80e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 505 DLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKI 584
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 585 TPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITT 664
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6325276 665 LNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLY 728
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
524-831 |
3.64e-129 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 391.43 E-value: 3.64e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 524 RSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTA 603
Cdd:cd17761 5 SSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAAGLTA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 604 YITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYN 683
Cdd:cd17761 85 AVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKFGRFD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 684 PNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISqdDVLPVEFLTMYISYAKEHIHPIIT 763
Cdd:cd17761 165 SYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIK--PEIDPDLLRKYIAYARKNVRPVLT 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6325276 764 EAAKTELVRAYVGMRKMGDDSRSDekrITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRS 831
Cdd:cd17761 243 EEAKQLIKDFYVEMRKSGQETPSP---VPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIMLN 307
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
522-831 |
1.10e-128 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 390.19 E-value: 1.10e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 522 LARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGL 601
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 602 TAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSR 681
Cdd:cd17757 82 TAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 682 YNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLyledkpeHISQDDVLPVEF----LTMYISYAKEh 757
Cdd:cd17757 162 YDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDL-------HSKREEAIEPPFtaeqLKRYIAYART- 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6325276 758 IHPIITEAAKTELVRAYVGMRkMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRS 831
Cdd:cd17757 234 FKPKLTKEAKDELVEQYKELR-QDDASGSTRSSYRITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKK 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
521-828 |
3.85e-128 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 389.05 E-value: 3.85e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 521 LLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG 600
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 601 LTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGS 680
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 681 RYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHIS--QDDVLPVEFLTMYISYAKEHI 758
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSqeNEGEIPISKLKRYIAYCRAKC 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6325276 759 HPIITEAAKTELVRAYVGMRK-MGDDSRSDEKR--ITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRL 828
Cdd:cd17756 241 APRLSEEAAEKLSNHYVTIRKdVRQNELESDNRssIPITVRQLEAIIRISESLAKMELSPIATEKHVEEAIRL 313
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
522-832 |
6.25e-127 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 385.61 E-value: 6.25e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 522 LARSIAPSIYELEDVKKGILLQLFGGTNKTfTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGL 601
Cdd:cd17758 2 LAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 602 TAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSR 681
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 682 YNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYL-EDKPEhiSQDDVLPVEFLTMYISYAKEhIHP 760
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQhNKQPD--SDFEPLDPKLLRAYIALAKR-KRP 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6325276 761 IITEAAKTELVRAYVGMRKmgdDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSA 832
Cdd:cd17758 238 TVPPALADYIVQAYVEMRQ---EAKRSKDFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
525-829 |
1.23e-118 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 364.46 E-value: 1.23e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 525 SIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAY 604
Cdd:cd17753 5 SIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGLTAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 605 ITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNP 684
Cdd:cd17753 85 VRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGGRYNP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 685 NLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAK-----HLTNLYLEDK-----------PEHISQD-DVLPVEFL 747
Cdd:cd17753 165 TLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKfvvgsHVRSHPENDEdregeeeknqrQRPKETKvEPIPQELL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 748 TMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSdekrITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVR 827
Cdd:cd17753 245 RKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGS----LPITVRHLESIIRISEAHAKMHLREYVSEEDVDMAIR 320
|
..
gi 6325276 828 LI 829
Cdd:cd17753 321 VM 322
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
521-832 |
3.12e-116 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 357.16 E-value: 3.12e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 521 LLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG 600
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 601 LTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGS 680
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 681 RYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEdkpehisqddvlpVEFLTMYISYAKEHIHP 760
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY-------------IKFLRKYIHYAKERIKP 227
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6325276 761 IITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSA 832
Cdd:cd17754 228 KLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITARTLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
521-830 |
4.24e-85 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 274.80 E-value: 4.24e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 521 LLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRY--RGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSA 598
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 599 VGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMsDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPI 678
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKM-GSQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 679 GSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLtnlyledkpehisqddvlpvEFLTMYISYAKEHI 758
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEHH--------------------QLLRKYISYARQYV 219
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6325276 759 HPIITEAAKTELVRAYVGMRKMGDDSRSDEkritATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIR 830
Cdd:cd17759 220 NPVLSKDASEALQEFYLELRKQNQLADSSP----ITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMK 287
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
521-832 |
2.94e-83 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 270.19 E-value: 2.94e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 521 LLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG 600
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 601 LTAYITRDvdTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGs 680
Cdd:cd17760 81 LTVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKG- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 681 RYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLtnlyLEDKPEHISQDDVLPVEFLTMYISYAKEhIHP 760
Cdd:cd17760 158 QYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFI----LENKGEPSKSSKLWSMEKMRTYFCLIKN-LRP 232
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6325276 761 IITEAAKTELVRAYVGMRKmgDDSRSDEKritATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSA 832
Cdd:cd17760 233 VLSDEANAILLRYYQLQRQ--SDCRNAAR---TTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
314-443 |
1.05e-50 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 174.21 E-value: 1.05e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 314 MRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIdrgviQEPARCERIDCNEPNSMSLIHNRCSFAD 393
Cdd:pfam17207 2 IRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKI-----TEPTKCPNPECGNKDPFKLVHEKSKFVD 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 6325276 394 KQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIP 443
Cdd:pfam17207 77 FQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
745-833 |
3.47e-36 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 131.51 E-value: 3.47e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 745 EFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSdekRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQE 824
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTGSGS---SIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEE 77
|
....*....
gi 6325276 825 AVRLIRSAI 833
Cdd:pfam17855 78 AIRLLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
194-307 |
1.27e-15 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 73.09 E-value: 1.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 194 FRNFLMSFKykfrkildereefinNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYKqtEDLYHQLLNYPQEVISIMD 273
Cdd:pfam14551 4 FKDFLEEFR---------------EDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFD--PDLAEALLENPYEYLPLFE 66
|
90 100 110
....*....|....*....|....*....|....
gi 6325276 274 QTIKDCMVSLIVDNNldydlDEIETKFYKVRPYN 307
Cdd:pfam14551 67 EALKEVVKELSEDPD-----YAEEEKEFQVRFYN 95
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
563-702 |
9.14e-09 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 54.61 E-value: 9.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 563 NILLCGDPSTSKSQILQYV-HKITPRGVYTsgkgssaVGLTAYIT-------RDVDTKQLVLESGALVLS--DGGVCCID 632
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLaAALSNRPVFY-------VQLTRDTTeedlfgrRNIDPGGASWVDGPLVRAarEGEIAVLD 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6325276 633 EFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARS-SILASANPIGSRYNpnlpvteniDLPPPLLSRF 702
Cdd:pfam07728 74 EINRANPDVLNSLLSLLDERRLLLPDGGELVKAAPDGfRLIATMNPLDRGLN---------ELSPALRSRF 135
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
631-829 |
2.45e-05 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 47.08 E-value: 2.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 631 IDEFDKMSDSTRSVLHEVMEQQTISIAKagiiTTLNARSS--ILASANPIgsrynpnlpvtENI---DLPPPLLSRFdLV 705
Cdd:COG0714 100 ADEINRAPPKTQSALLEAMEERQVTIPG----GTYKLPEPflVIATQNPI-----------EQEgtyPLPEAQLDRF-LL 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 706 YLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTmyisyAKEHIHPIITEAAkTELVRAyvgMRKMGDdsr 785
Cdd:COG0714 164 KLYIGYPDAEEEREILRRHTGRHLAEVEPVLSPEELLALQELV-----RQVHVSEAVLDYI-VDLVRA---TREHPD--- 231
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 6325276 786 sdeKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLI 829
Cdd:COG0714 232 ---LRKGPSPRASIALLRAARALALLDGRDYVTPDDVKAVAGPV 272
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
563-705 |
4.99e-03 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 38.67 E-value: 4.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325276 563 NILLCGDPSTSKSQILQYVHKITPRG----VYTSGkgsSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMS 638
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPgapfLYLNA---SDLLEGLVVAELFGHFLVRLLFELAEKAKPGVLFIDEIDSLS 97
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6325276 639 DSTRSVLHEVMEQQTISIAKagiittlNARSSILASANPIgsrynpnlpvtENIDLPPPLLSRFDLV 705
Cdd:cd00009 98 RGAQNALLRVLETLNDLRID-------RENVRVIGATNRP-----------LLGDLDRALYDRLDIR 146
|
|
| |
