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Conserved domains on  [gi|6323423|ref|NP_013495|]
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Ccw14p [Saccharomyces cerevisiae S288C]

Protein Classification

CFEM domain-containing protein( domain architecture ID 10654505)

CFEM domain-containing protein is a fungal specific cysteine rich membrane protein; similar to GPI-anchored cell wall protein involved in stabilizing the cell wall

Gene Ontology:  GO:0046872
PubMed:  12633989
SCOP:  4005677

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CFEM smart00747
eight cysteine-containing domain present in fungal extracellular membrane proteins;
20-84 5.01e-12

eight cysteine-containing domain present in fungal extracellular membrane proteins;


:

Pssm-ID: 128986  Cd Length: 65  Bit Score: 59.44  E-value: 5.01e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6323423      20 VLATPPACLLACVAQVGKSSsTCdSLNQVTCYCEHEN--SAVKKCLDSICPNNDADAAYSAFKSSCS 84
Cdd:smart00747   1 IVDNLPSCALPCVNQALGSF-PC-SLTDAKCLCVNPEfgSAITDCVAKKCKGSDADSVISATKSVCS 65
 
Name Accession Description Interval E-value
CFEM smart00747
eight cysteine-containing domain present in fungal extracellular membrane proteins;
20-84 5.01e-12

eight cysteine-containing domain present in fungal extracellular membrane proteins;


Pssm-ID: 128986  Cd Length: 65  Bit Score: 59.44  E-value: 5.01e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6323423      20 VLATPPACLLACVAQVGKSSsTCdSLNQVTCYCEHEN--SAVKKCLDSICPNNDADAAYSAFKSSCS 84
Cdd:smart00747   1 IVDNLPSCALPCVNQALGSF-PC-SLTDAKCLCVNPEfgSAITDCVAKKCKGSDADSVISATKSVCS 65
CFEM pfam05730
CFEM domain; This fungal specific cysteine rich domain is found in some proteins with proposed ...
 21-84 2.06e-09

CFEM domain; This fungal specific cysteine rich domain is found in some proteins with proposed roles in fungal pathogenesis. The structure of the CFEM domain containing protein 'Surface antigen protein 2' from Candida albicans has been solved.


Pssm-ID: 399033 [Multi-domain]  Cd Length: 66  Bit Score: 52.45  E-value: 2.06e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6323423     21 LATPPACLLACVAQVGKSSSTCdSLNQVTCYC--EHENSAVKKCLDSICPNNDADAAYSAFKSSCS 84
Cdd:pfam05730   2 LAALPACAQPCVAQALKASSLC-SLTDFACLCtnPNFQGAITDCVASACTADDALAAINAASSICS 66
 
Name Accession Description Interval E-value
CFEM smart00747
eight cysteine-containing domain present in fungal extracellular membrane proteins;
20-84 5.01e-12

eight cysteine-containing domain present in fungal extracellular membrane proteins;


Pssm-ID: 128986  Cd Length: 65  Bit Score: 59.44  E-value: 5.01e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6323423      20 VLATPPACLLACVAQVGKSSsTCdSLNQVTCYCEHEN--SAVKKCLDSICPNNDADAAYSAFKSSCS 84
Cdd:smart00747   1 IVDNLPSCALPCVNQALGSF-PC-SLTDAKCLCVNPEfgSAITDCVAKKCKGSDADSVISATKSVCS 65
CFEM pfam05730
CFEM domain; This fungal specific cysteine rich domain is found in some proteins with proposed ...
 21-84 2.06e-09

CFEM domain; This fungal specific cysteine rich domain is found in some proteins with proposed roles in fungal pathogenesis. The structure of the CFEM domain containing protein 'Surface antigen protein 2' from Candida albicans has been solved.


Pssm-ID: 399033 [Multi-domain]  Cd Length: 66  Bit Score: 52.45  E-value: 2.06e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6323423     21 LATPPACLLACVAQVGKSSSTCdSLNQVTCYC--EHENSAVKKCLDSICPNNDADAAYSAFKSSCS 84
Cdd:pfam05730   2 LAALPACAQPCVAQALKASSLC-SLTDFACLCtnPNFQGAITDCVASACTADDALAAINAASSICS 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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