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Conserved domains on  [gi|62990174|ref|NP_898964|]
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protein phosphatase 1 regulatory subunit 29 precursor [Mus musculus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
60-205 2.19e-16

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 82.29  E-value: 2.19e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174  60 LRLNENKLKAvLYSSLNRFGNLTDLNLTKNEISYIedGAFLGQ-TSLQVLQLGYNRLSNLTEGmLRGMSRLQFLFVQHNL 138
Cdd:COG4886 118 LDLSGNQLTD-LPEELANLTNLKELDLSNNQLTDL--PEPLGNlTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQ 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 62990174 139 IEVVtPTAFSECPSLISIDLSSNRLSRLDgATFASLASLMVCELAGNPFNCECDLFGF--LAWLVVFNN 205
Cdd:COG4886 194 ITDL-PEPLGNLTNLEELDLSGNQLTDLP-EPLANLTNLETLDLSNNQLTDLPELGNLtnLEELDLSNN 260
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
60-205 2.19e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 82.29  E-value: 2.19e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174  60 LRLNENKLKAvLYSSLNRFGNLTDLNLTKNEISYIedGAFLGQ-TSLQVLQLGYNRLSNLTEGmLRGMSRLQFLFVQHNL 138
Cdd:COG4886 118 LDLSGNQLTD-LPEELANLTNLKELDLSNNQLTDL--PEPLGNlTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQ 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 62990174 139 IEVVtPTAFSECPSLISIDLSSNRLSRLDgATFASLASLMVCELAGNPFNCECDLFGF--LAWLVVFNN 205
Cdd:COG4886 194 ITDL-PEPLGNLTNLEELDLSGNQLTDLP-EPLANLTNLETLDLSNNQLTDLPELGNLtnLEELDLSNN 260
LRR_8 pfam13855
Leucine rich repeat;
80-139 4.07e-13

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 64.47  E-value: 4.07e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174    80 NLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLI 139
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 157-227 3.10e-07

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 54.32  E-value: 3.10e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 62990174    157 DLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLL 227
Cdd:TIGR00864    1 DISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPGALAGQPLL 71
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 60-187 1.49e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.78  E-value: 1.49e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174  60 LRLNENKLKA-----------VLY---------SSLNRFGNLTDLNLTKNEISYIEDgaFLGQTSLQVLQLGYNR----- 114
Cdd:cd21340   7 LYLNDKNITKidnlslcknlkVLYlydnkitkiENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRisvve 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174 115 ----LSNLTE------------------GMLRGMSR-LQFLFVQHNLIEVVTPtaFSECPSLISIDLSSNRLSRLD--GA 169
Cdd:cd21340  85 glenLTNLEElhienqrlppgekltfdpRSLAALSNsLRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLD 162

                       170
                ....*....|....*...
gi 62990174 170 TFASLASLMVCELAGNPF 187
Cdd:cd21340 163 LLSSWPSLRELDLTGNPV 180
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 60-188 2.09e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.22  E-value: 2.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174   60 LRLNENKLKAVLYSSLnRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLI 139
Cdd:PLN00113 457 LSLARNKFFGGLPDSF-GSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQL 535

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 62990174  140 EVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFN 188
Cdd:PLN00113 536 SGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLH 584
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
60-205 2.19e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 82.29  E-value: 2.19e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174  60 LRLNENKLKAvLYSSLNRFGNLTDLNLTKNEISYIedGAFLGQ-TSLQVLQLGYNRLSNLTEGmLRGMSRLQFLFVQHNL 138
Cdd:COG4886 118 LDLSGNQLTD-LPEELANLTNLKELDLSNNQLTDL--PEPLGNlTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQ 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 62990174 139 IEVVtPTAFSECPSLISIDLSSNRLSRLDgATFASLASLMVCELAGNPFNCECDLFGF--LAWLVVFNN 205
Cdd:COG4886 194 ITDL-PEPLGNLTNLEELDLSGNQLTDLP-EPLANLTNLETLDLSNNQLTDLPELGNLtnLEELDLSNN 260
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
60-187 3.16e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 75.74  E-value: 3.16e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174  60 LRLNENKLKaVLYSSLNRFGNLTDLNLTKNEISYIedGAFLGQ-TSLQVLQLGYNRLSNLTEGmLRGMSRLQFLFVQHNL 138
Cdd:COG4886 164 LDLSNNQLT-DLPEELGNLTNLKELDLSNNQITDL--PEPLGNlTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQ 239

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 62990174 139 IEVVTptAFSECPSLISIDLSSNRLSRLDgaTFASLASLMVCELAGNPF 187
Cdd:COG4886 240 LTDLP--ELGNLTNLEELDLSNNQLTDLP--PLANLTNLKTLDLSNNQL 284
LRR_8 pfam13855
Leucine rich repeat;
80-139 4.07e-13

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 64.47  E-value: 4.07e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174    80 NLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLI 139
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
39-197 4.06e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 65.73  E-value: 4.06e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174  39 CSQNQppYETIPQHINSTVH--DLRLNENKLKAvLYSSLNRFGNLTDLNLTKNEISYIEDGafLGQ-TSLQVLQLGYNRL 115
Cdd:COG4886 166 LSNNQ--LTDLPEELGNLTNlkELDLSNNQITD-LPEPLGNLTNLEELDLSGNQLTDLPEP--LANlTNLETLDLSNNQL 240

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174 116 SNLTEgmLRGMSRLQFLFVQHNLIEVVTPTAfsECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFG 195
Cdd:COG4886 241 TDLPE--LGNLTNLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLIL 316


                ..
gi 62990174 196 FL 197
Cdd:COG4886 317 LL 318
LRR_8 pfam13855
Leucine rich repeat;
103-163 9.50e-11

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 57.92  E-value: 9.50e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 62990174   103 TSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRL 163
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
40-188 1.59e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.18  E-value: 1.59e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174  40 SQNQPPYETIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKN-EISYIED--------------GAFLGQ-T 103
Cdd:COG4886  57 LRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNeELSNLTNlesldlsgnqltdlPEELANlT 136

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174 104 SLQVLQLGYNRLSNLTEGmLRGMSRLQFLFVQHNLIEVVtPTAFSECPSLISIDLSSNRLSRLdGATFASLASLMVCELA 183
Cdd:COG4886 137 NLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLS 213


                ....*
gi 62990174 184 GNPFN 188
Cdd:COG4886 214 GNQLT 218
LRR_8 pfam13855
Leucine rich repeat;
127-187 1.57e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 54.45  E-value: 1.57e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 62990174   127 SRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPF 187
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 157-227 3.10e-07

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 54.32  E-value: 3.10e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 62990174    157 DLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLL 227
Cdd:TIGR00864    1 DISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPGALAGQPLL 71
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 60-187 1.49e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.78  E-value: 1.49e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174  60 LRLNENKLKA-----------VLY---------SSLNRFGNLTDLNLTKNEISYIEDgaFLGQTSLQVLQLGYNR----- 114
Cdd:cd21340   7 LYLNDKNITKidnlslcknlkVLYlydnkitkiENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRisvve 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174 115 ----LSNLTE------------------GMLRGMSR-LQFLFVQHNLIEVVTPtaFSECPSLISIDLSSNRLSRLD--GA 169
Cdd:cd21340  85 glenLTNLEElhienqrlppgekltfdpRSLAALSNsLRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLD 162

                       170
                ....*....|....*...
gi 62990174 170 TFASLASLMVCELAGNPF 187
Cdd:cd21340 163 LLSSWPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
55-115 1.51e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.98  E-value: 1.51e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 62990174    55 STVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRL 115
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 75-165 1.03e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 44.39  E-value: 1.03e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174  75 LNRFGNLTDLNLTKNEIS--------------YIED-----G---AFLGQT------SLQVLQLGYNRLSNLTEgmLRGM 126
Cdd:cd21340  64 LENLVNLKKLYLGGNRISvveglenltnleelHIENqrlppGeklTFDPRSlaalsnSLRVLNISGNNIDSLEP--LAPL 141

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 62990174 127 SRLQFLFVQHNLIEVVTPTA--FSECPSLISIDLSSNRLSR 165
Cdd:cd21340 142 RNLEQLDASNNQISDLEELLdlLSSWPSLRELDLTGNPVCK 182
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 60-188 2.09e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.22  E-value: 2.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174   60 LRLNENKLKAVLYSSLnRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLI 139
Cdd:PLN00113 457 LSLARNKFFGGLPDSF-GSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQL 535

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 62990174  140 EVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFN 188
Cdd:PLN00113 536 SGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLH 584
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 60-187 2.28e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 44.84  E-value: 2.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174   60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYiEDGAFLGQ-TSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNL 138
Cdd:PLN00113 193 LTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSG-EIPYEIGGlTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNK 271

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 62990174  139 IEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPF 187
Cdd:PLN00113 272 LSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNF 320
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 60-228 8.02e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 43.30  E-value: 8.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174   60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLS-NLTEgmLRGMSRLQFLFVQHNL 138
Cdd:PLN00113 409 VRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFgGLPD--SFGSKRLENLDLSRNQ 486

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174  139 IEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLfGFlAWLVVFNNVTKNYDRLQCESP 218
Cdd:PLN00113 487 FSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPA-SF-SEMPVLSQLDLSQNQLSGEIP 564

                        170
                 ....*....|
gi 62990174  219 REFAGYPLLV 228
Cdd:PLN00113 565 KNLGNVESLV 574
PLN03150 PLN03150
hypothetical protein; Provisional
 39-146 1.37e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.11  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174   39 CSQNQPPYETIPQHINST-----VHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYN 113
Cdd:PLN03150 397 CVPQQHPWSGADCQFDSTkgkwfIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYN 476

                         90       100       110
                 ....*....|....*....|....*....|...
gi 62990174  114 RLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTA 146
Cdd:PLN03150 477 SFNGSIPESLGQLTSLRILNLNGNSLSGRVPAA 509
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
 80-161 3.85e-03

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 38.29  E-value: 3.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174    80 NLTDLNLTKNeISYIEDGAFLGQTSLQVLQLGynrlSNLTE-GmlrgmsrlQFLFVQHNLIEVVTPT--------AFSEC 150
Cdd:pfam13306  12 SLTSITIPSS-LTSIGEYAFSNCTSLKSITLP----SSLTSiG--------SYAFYNCSLTSITIPSsltsigeyAFSNC 78

                          90
                  ....*....|.
gi 62990174   151 PSLISIDLSSN 161
Cdd:pfam13306  79 SNLKSITLPSN 89
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 40-139 9.77e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.45  E-value: 9.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62990174   40 SQNQPPyETIPQHIN--STVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSN 117
Cdd:PLN00113 483 SRNQFS-GAVPRKLGslSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSG 561

                         90       100
                 ....*....|....*....|..
gi 62990174  118 LTEGMLRGMSRLQFLFVQHNLI 139
Cdd:PLN00113 562 EIPKNLGNVESLVQVNISHNHL 583
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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