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Conserved domains on  [gi|62901109|sp|Q9JLI7|]
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RecName: Full=Sperm-associated antigen 6; AltName: Full=Axoneme central apparatus protein; AltName: Full=Protein PF16 homolog

Protein Classification

armadillo/beta-catenin-like repeat-containing protein( domain architecture ID 1000979)

armadillo/beta-catenin-like repeat-containing protein similar to Saccharomyces cerevisiae vacuolar protein 8 that functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SRP1 super family cl34886
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
112-423 1.71e-21

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5064:

Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 97.65  E-value: 1.71e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 112 KHSPQLaQAIVDCGALDTLVICLEDFDPGVKE-AAAWALGYIARHNTELSQAVVDAGAIPLLVLCIQEPEIALKRIAASA 190
Cdd:COG5064 102 ETSPPI-QPVIDAGVVPRFVEFMDEIQRDMLQfEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWA 180

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 191 LSDISKHSPELAQTVVDAGAIAHLAQMILN--PDAKLKRQVLSALSQIAKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVK 268
Cdd:COG5064 181 LGNIAGDSEGCRDYVLQCGALEPLLGLLLSsaIHISMLRNATWTLSNLCRGKNPPPDWSNISQALPILAKLIYSRDPEVL 260

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 269 KNACTLIREIAKHTPELSQLIVNAGGVAAVIDCIGSCKGNIRLPGIMMLGYVAAHSEnLAMAVIISKGVPQLSICLSEEP 348
Cdd:COG5064 261 VDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSD-DQTQVIINCGALKAFRSLLSSP 339

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 62901109 349 EDHIKAAAAWALGQLGRHTPEHARAVAVTNTLPVLLSLYMSPEssedlqLKSKK----AIKNILQKCTYLPALEPFLYD 423
Cdd:COG5064 340 KENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAE------YKIKKeacwAISNATSGGLNRPDIIRYLVS 412
SRP1 super family cl34886
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
34-183 1.21e-03

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5064:

Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 41.41  E-value: 1.21e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109  34 IETLQNAGVMSLLRPLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKGDILPQLVYSLAEQNRFYKKAAAFVLRAVGKH 113
Cdd:COG5064 278 IQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVIINCGALKAFRSLLSSPKENIRKEACWTISNITAG 357

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 62901109 114 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIARHNTELSQAV---VDAGAIPLL--VLCIQE---PEIAL 183
Cdd:COG5064 358 NTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWAISNATSGGLNRPDIIrylVSQGFIKPLcdLLDVVDnkiIEVAL 435
 
Name Accession Description Interval E-value
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
112-423 1.71e-21

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 97.65  E-value: 1.71e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 112 KHSPQLaQAIVDCGALDTLVICLEDFDPGVKE-AAAWALGYIARHNTELSQAVVDAGAIPLLVLCIQEPEIALKRIAASA 190
Cdd:COG5064 102 ETSPPI-QPVIDAGVVPRFVEFMDEIQRDMLQfEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWA 180

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 191 LSDISKHSPELAQTVVDAGAIAHLAQMILN--PDAKLKRQVLSALSQIAKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVK 268
Cdd:COG5064 181 LGNIAGDSEGCRDYVLQCGALEPLLGLLLSsaIHISMLRNATWTLSNLCRGKNPPPDWSNISQALPILAKLIYSRDPEVL 260

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 269 KNACTLIREIAKHTPELSQLIVNAGGVAAVIDCIGSCKGNIRLPGIMMLGYVAAHSEnLAMAVIISKGVPQLSICLSEEP 348
Cdd:COG5064 261 VDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSD-DQTQVIINCGALKAFRSLLSSP 339

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 62901109 349 EDHIKAAAAWALGQLGRHTPEHARAVAVTNTLPVLLSLYMSPEssedlqLKSKK----AIKNILQKCTYLPALEPFLYD 423
Cdd:COG5064 340 KENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAE------YKIKKeacwAISNATSGGLNRPDIIRYLVS 412
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 114-154 2.84e-07

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 46.68  E-value: 2.84e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 62901109   114 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIAR 154
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 114-154 1.51e-05

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 42.03  E-value: 1.51e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 62901109    114 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIAR 154
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 64-229 1.07e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 42.01  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109    64 ALGRLANYNDDLAEAVVKG---DILPQLVYS---LAEQNrfykkaAAFVL----RAVGKHSPQlaqaIVDCGALDTLVIC 133
Cdd:PLN03200  170 ALRNLCGSTDGFWSATLEAggvDILVKLLSSgnsDAQAN------AASLLarlmMAFESSISK----VLDAGAVKQLLKL 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109   134 L-EDFDPGVKEAAAWALGYIARHNTELSQAVVDAGAIPLLVL--------CIQ-EPEIALKRIAASALSDIS-------- 195
Cdd:PLN03200  240 LgQGNEVSVRAEAAGALEALSSQSKEAKQAIADAGGIPALINatvapskeFMQgEFAQALQENAMGALANICggmsalil 319

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 62901109   196 -----KHSPELAQTVVDA-GAIAHlAQMILNPDAKLKRQV 229
Cdd:PLN03200  320 ylgelSESPRSPAPIADTlGALAY-ALMVFDSSAESTRAF 358
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
34-183 1.21e-03

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 41.41  E-value: 1.21e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109  34 IETLQNAGVMSLLRPLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKGDILPQLVYSLAEQNRFYKKAAAFVLRAVGKH 113
Cdd:COG5064 278 IQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVIINCGALKAFRSLLSSPKENIRKEACWTISNITAG 357

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 62901109 114 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIARHNTELSQAV---VDAGAIPLL--VLCIQE---PEIAL 183
Cdd:COG5064 358 NTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWAISNATSGGLNRPDIIrylVSQGFIKPLcdLLDVVDnkiIEVAL 435
 
Name Accession Description Interval E-value
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
112-423 1.71e-21

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 97.65  E-value: 1.71e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 112 KHSPQLaQAIVDCGALDTLVICLEDFDPGVKE-AAAWALGYIARHNTELSQAVVDAGAIPLLVLCIQEPEIALKRIAASA 190
Cdd:COG5064 102 ETSPPI-QPVIDAGVVPRFVEFMDEIQRDMLQfEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWA 180

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 191 LSDISKHSPELAQTVVDAGAIAHLAQMILN--PDAKLKRQVLSALSQIAKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVK 268
Cdd:COG5064 181 LGNIAGDSEGCRDYVLQCGALEPLLGLLLSsaIHISMLRNATWTLSNLCRGKNPPPDWSNISQALPILAKLIYSRDPEVL 260

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 269 KNACTLIREIAKHTPELSQLIVNAGGVAAVIDCIGSCKGNIRLPGIMMLGYVAAHSEnLAMAVIISKGVPQLSICLSEEP 348
Cdd:COG5064 261 VDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSD-DQTQVIINCGALKAFRSLLSSP 339

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 62901109 349 EDHIKAAAAWALGQLGRHTPEHARAVAVTNTLPVLLSLYMSPEssedlqLKSKK----AIKNILQKCTYLPALEPFLYD 423
Cdd:COG5064 340 KENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAE------YKIKKeacwAISNATSGGLNRPDIIRYLVS 412
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
11-310 7.38e-15

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 76.85  E-value: 7.38e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109  11 EQYQKARTQFVQMVAElATRPQnIETLQNAGVMSLLRPLLLDVVPTIQQ-TAALALGRLANYNDDLAEAVVKGDILPQLV 89
Cdd:COG5064  86 EQQLQAVYKFRKLLSK-ETSPP-IQPVIDAGVVPRFVEFMDEIQRDMLQfEAAWALTNIASGTTQQTKVVVDAGAVPLFI 163

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109  90 YSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVK--EAAAWALGYIAR-HNTELSQAVVDA 166
Cdd:COG5064 164 QLLSSTEDDVREQAVWALGNIAGDSEGCRDYVLQCGALEPLLGLLLSSAIHISmlRNATWTLSNLCRgKNPPPDWSNISQ 243

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 167 gAIPLL--VLCIQEPEIALKriAASALSDISKHSPELAQTVVDAGAIAHLAQMILNPDAKLKRQVLSALSQIAKHSVDLA 244
Cdd:COG5064 244 -ALPILakLIYSRDPEVLVD--ACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQT 320

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 62901109 245 EMVVEAEIFPVVLTCLKDKDEYVKKNACTLIREIAKHTPELSQLIVNAGGVAAVIDCIGSCKGNIR 310
Cdd:COG5064 321 QVIINCGALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAEYKIK 386
HEAT COG1413
HEAT repeat [General function prediction only];
126-279 2.49e-09

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 55.41  E-value: 2.49e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 126 ALDTLVICLEDFDPGVKEAAAWALGYIArhntelsqavvDAGAIPLLVLCIQEPEIALKRIAASALSDISkhspelaqtv 205
Cdd:COG1413  17 AVPALIAALADEDPDVRAAAARALGRLG-----------DPRAVPALLEALKDPDPEVRAAAAEALGRIG---------- 75

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 62901109 206 vDAGAIAHLAQMILNPDAKLKRQVLSALSQIAkhsvdlaemvvEAEIFPVVLTCLKDKDEYVKKNACTLIREIA 279
Cdd:COG1413  76 -DPEAVPALIAALKDEDPEVRRAAAEALGRLG-----------DPAAVPALLEALKDPDWEVRRAAARALGRLG 137
HEAT COG1413
HEAT repeat [General function prediction only];
37-194 2.67e-08

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 52.71  E-value: 2.67e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109  37 LQNAGVMSLLRPLLLDVVPTIQQTAALALGRLANynddlAEAVvkgdilPQLVYSLAEQNRFYKKAAAFVLRAVGkhspq 116
Cdd:COG1413  12 LGDPAAVPALIAALADEDPDVRAAAARALGRLGD-----PRAV------PALLEALKDPDPEVRAAAAEALGRIG----- 75

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 62901109 117 laqaivDCGALDTLVICLEDFDPGVKEAAAWALGYIArhntelsqavvDAGAIPLLVLCIQEPEIALKRIAASALSDI 194
Cdd:COG1413  76 ------DPEAVPALIAALKDEDPEVRRAAAEALGRLG-----------DPAAVPALLEALKDPDWEVRRAAARALGRL 136
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 114-154 2.84e-07

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 46.68  E-value: 2.84e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 62901109   114 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIAR 154
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
HEAT COG1413
HEAT repeat [General function prediction only];
141-278 9.05e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 45.39  E-value: 9.05e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109 141 VKEAAAWALGYIArhntelsqavvDAGAIPLLVLCIQEPEIALKRIAASALSDISkhspelaqtvvDAGAIAHLAQMILN 220
Cdd:COG1413   1 VRRAAARALGRLG-----------DPAAVPALIAALADEDPDVRAAAARALGRLG-----------DPRAVPALLEALKD 58

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 62901109 221 PDAKLKRQVLSALSQIAkhsvdlaemvvEAEIFPVVLTCLKDKDEYVKKNACTLIREI 278
Cdd:COG1413  59 PDPEVRAAAAEALGRIG-----------DPEAVPALIAALKDEDPEVRRAAAEALGRL 105
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 114-154 1.51e-05

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 42.03  E-value: 1.51e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 62901109    114 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIAR 154
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 198-238 1.14e-04

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 39.33  E-value: 1.14e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 62901109    198 SPELAQTVVDAGAIAHLAQMILNPDAKLKRQVLSALSQIAK 238
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 198-237 1.25e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 39.36  E-value: 1.25e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 62901109   198 SPELAQTVVDAGAIAHLAQMILNPDAKLKRQVLSALSQIA 237
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 156-195 4.53e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.82  E-value: 4.53e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 62901109   156 NTELSQAVVDAGAIPLLVLCIQEPEIALKRIAASALSDIS 195
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 139-194 5.55e-04

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 38.12  E-value: 5.55e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 62901109   139 PGVKEAAAWALGYIARHNTELSQAVVDAgAIPLLVLCIQEPEIALKRIAASALSDI 194
Cdd:pfam13513   1 WRVREAAALALGSLAEGGPDLLAPAVPE-LLPALLPLLNDDSDLVREAAAWALGRL 55
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 130-234 7.23e-04

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.47  E-value: 7.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109   130 LVICLEDFDPGVKEAAAWALGYIArhntelsqavvDAGAIPLLVLCIQEPEIALKRIAASALSDISkhspelaqtvvDAG 209
Cdd:pfam13646   5 LQALLRDPDPEVRAAAIRALGRIG-----------DPEAVPALLELLKDEDPAVRRAAAEALGKIG-----------DPE 62

                          90       100
                  ....*....|....*....|....*.
gi 62901109   210 AIAHLAQMILN-PDAKLKRQVLSALS 234
Cdd:pfam13646  63 ALPALLELLRDdDDDVVRAAAAEALA 88
Adaptin_N pfam01602
Adaptin N terminal region; This family consists of the N terminal region of various alpha, ...
 17-333 1.03e-03

Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles.


Pssm-ID: 396262 [Multi-domain]  Cd Length: 523  Bit Score: 41.45  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109    17 RTQFVQMVAelatrpqnIETLQNAGVMSLLRPLLLDVV-------PTIQQTAALALGRLANYNDDLAEavvkgDILPQLV 89
Cdd:pfam01602  91 PNQLIRGLA--------LRTLSCIRVPELARDLAPDIKkllvdrsPYVRKKAALAILKLYRKSPDLVR-----DFVPELK 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109    90 YSLAEQNRFYKKAAAFVLRAVgKHSPQLAqaivdCGALDTLVICLEDFdpgVKEAAAWALGYI-------ARHNTELSQ- 161
Cdd:pfam01602 158 ELLSDKDPGVQSAAVALLYEI-CKNDRLY-----LKLLPLLFRRLCNL---LGVLNPWLQVKIlrlltrlAPLDPLLPKe 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109   162 --------------AVVDAGA---------IPLLVLCIQ-------EPEIALKRIAASALSDISKHSP------------ 199
Cdd:pfam01602 229 lledllnllqnsnnAVLYETAntivhlapaPELIVLAVNalgrllsSPDENLRYVALRNLNKIVMKEPkavqhldliifc 308

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109   200 --------------ELAQTVVDAGAIAHLAQMILN-----PDAKLKRQVLSALSQIAKHSVDLAEMVVeaeifPVVLTCL 260
Cdd:pfam01602 309 lktdddisirlralDLLYALVNESNVKEIVKELLKyvheiADPDFKIELVRAIGRLAEKFPTDAEWYL-----DVLLDLL 383

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 62901109   261 KDKDEYVKKNACTLIREIAKHTPELSQLIVNAggVAAVIDCIGSCkgNIRLPGIMMLGYVAAHSENLAMAVII 333
Cdd:pfam01602 384 SLAGSYVVDEIVEVIRDIIQNVPELREYILEH--LCELLEDIESP--EALAAALWILGEYGELIPNGSSPPDL 452
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 64-229 1.07e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 42.01  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109    64 ALGRLANYNDDLAEAVVKG---DILPQLVYS---LAEQNrfykkaAAFVL----RAVGKHSPQlaqaIVDCGALDTLVIC 133
Cdd:PLN03200  170 ALRNLCGSTDGFWSATLEAggvDILVKLLSSgnsDAQAN------AASLLarlmMAFESSISK----VLDAGAVKQLLKL 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109   134 L-EDFDPGVKEAAAWALGYIARHNTELSQAVVDAGAIPLLVL--------CIQ-EPEIALKRIAASALSDIS-------- 195
Cdd:PLN03200  240 LgQGNEVSVRAEAAGALEALSSQSKEAKQAIADAGGIPALINatvapskeFMQgEFAQALQENAMGALANICggmsalil 319

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 62901109   196 -----KHSPELAQTVVDA-GAIAHlAQMILNPDAKLKRQV 229
Cdd:PLN03200  320 ylgelSESPRSPAPIADTlGALAY-ALMVFDSSAESTRAF 358
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
34-183 1.21e-03

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 41.41  E-value: 1.21e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109  34 IETLQNAGVMSLLRPLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKGDILPQLVYSLAEQNRFYKKAAAFVLRAVGKH 113
Cdd:COG5064 278 IQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVIINCGALKAFRSLLSSPKENIRKEACWTISNITAG 357

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 62901109 114 SPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIARHNTELSQAV---VDAGAIPLL--VLCIQE---PEIAL 183
Cdd:COG5064 358 NTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWAISNATSGGLNRPDIIrylVSQGFIKPLcdLLDVVDnkiIEVAL 435
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
177-375 4.18e-03

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 39.83  E-value: 4.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109  177 QEPEIALKRIAASALSDISKHSPELAQTVVDAGAIAHLAQMILNPDAKLKRQVLSALSQiakhsvdlaemVVEAEIFPVV 256
Cdd:PRK13800 589 RAPAEGVSRAAAPATAPEPPSPRILAVLALDAPSVAELAPYLADPDPGVRRTAVAVLTE-----------TTPPGFGPAL 657

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62901109  257 LTCLKDKDEYVKKNACTLIREIAKHTPELSQL---------IVNA-----------GGVAAVIDCIGSCKGNIRLPGIMM 316
Cdd:PRK13800 658 VAALGDGAAAVRRAAAEGLRELVEVLPPAPALrdhlgspdpVVRAaaldvlralraGDAALFAAALGDPDHRVRIEAVRA 737

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 62901109  317 LGYV--------AAHSENLAMAVIISKGVPQLSI----------CLSEEPEDHIKAAAAWALGQLGRHTPEHARAVA 375
Cdd:PRK13800 738 LVSVddvesvagAATDENREVRIAVAKGLATLGAggapagdavrALTGDPDPLVRAAALAALAELGCPPDDVAAATA 814
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 156-196 4.53e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.10  E-value: 4.53e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 62901109    156 NTELSQAVVDAGAIPLLVLCIQEPEIALKRIAASALSDISK 196
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 99-152 4.80e-03

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 35.42  E-value: 4.80e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 62901109    99 YKKAAAFVLRAVGKHSPQLAQAIVDcGALDTLVICLEDFDPGVKEAAAWALGYI 152
Cdd:pfam13513   3 VREAAALALGSLAEGGPDLLAPAVP-ELLPALLPLLNDDSDLVREAAAWALGRL 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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