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Conserved domains on  [gi|614712334|gb|AHX58144|]
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male fertility factor kl5, partial [Drosophila sechellia x Drosophila simulans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DHC_N1 super family cl20356
Dynein heavy chain, N-terminal region 1; Dynein heavy chains interact with other heavy chains ...
 1-151 1.60e-15

Dynein heavy chain, N-terminal region 1; Dynein heavy chains interact with other heavy chains to form dimers, and with intermediate chain-light chain complexes to form a basal cargo binding unit. The region featured in this family includes the sequences implicated in mediating these interactions. It is thought to be flexible and not to adopt a rigid conformation.


The actual alignment was detected with superfamily member pfam08385:

Pssm-ID: 462457  Cd Length: 560  Bit Score: 72.22  E-value: 1.60e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 614712334    1 VKKEFINFKNVFTVLGLNELPTDDCFPKVSGAISFLKKLGHRIIGLHKEHELYEYPLFDNErGGYVSDIFNIMVQEIDDF 80
Cdd:pfam08385 351 FKKELDAVKKIFDKQKYNPSPIAKNMPPVAGAIIWARQLFRRIQEPMKRFKEELGLLKHAE-GKKVIKKYNELAKKLDEY 429

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 614712334   81 TKMLLDKWIVECWQGIQQDIILTLLVKDEANK--LRVNFTERLIFALKDIKVVRLLSCDVSVNLTKFFCREDE 151
Cdd:pfam08385 430 ERLIYEAWLKEVEEASEGNLKRPLLVRHPETGklLSVNFDPQLLALLREVKYLQKLGFEIPESALNIALKEER 502
 
Name Accession Description Interval E-value
DHC_N1 pfam08385
Dynein heavy chain, N-terminal region 1; Dynein heavy chains interact with other heavy chains ...
 1-151 1.60e-15

Dynein heavy chain, N-terminal region 1; Dynein heavy chains interact with other heavy chains to form dimers, and with intermediate chain-light chain complexes to form a basal cargo binding unit. The region featured in this family includes the sequences implicated in mediating these interactions. It is thought to be flexible and not to adopt a rigid conformation.


Pssm-ID: 462457  Cd Length: 560  Bit Score: 72.22  E-value: 1.60e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 614712334    1 VKKEFINFKNVFTVLGLNELPTDDCFPKVSGAISFLKKLGHRIIGLHKEHELYEYPLFDNErGGYVSDIFNIMVQEIDDF 80
Cdd:pfam08385 351 FKKELDAVKKIFDKQKYNPSPIAKNMPPVAGAIIWARQLFRRIQEPMKRFKEELGLLKHAE-GKKVIKKYNELAKKLDEY 429

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 614712334   81 TKMLLDKWIVECWQGIQQDIILTLLVKDEANK--LRVNFTERLIFALKDIKVVRLLSCDVSVNLTKFFCREDE 151
Cdd:pfam08385 430 ERLIYEAWLKEVEEASEGNLKRPLLVRHPETGklLSVNFDPQLLALLREVKYLQKLGFEIPESALNIALKEER 502
 
Name Accession Description Interval E-value
DHC_N1 pfam08385
Dynein heavy chain, N-terminal region 1; Dynein heavy chains interact with other heavy chains ...
 1-151 1.60e-15

Dynein heavy chain, N-terminal region 1; Dynein heavy chains interact with other heavy chains to form dimers, and with intermediate chain-light chain complexes to form a basal cargo binding unit. The region featured in this family includes the sequences implicated in mediating these interactions. It is thought to be flexible and not to adopt a rigid conformation.


Pssm-ID: 462457  Cd Length: 560  Bit Score: 72.22  E-value: 1.60e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 614712334    1 VKKEFINFKNVFTVLGLNELPTDDCFPKVSGAISFLKKLGHRIIGLHKEHELYEYPLFDNErGGYVSDIFNIMVQEIDDF 80
Cdd:pfam08385 351 FKKELDAVKKIFDKQKYNPSPIAKNMPPVAGAIIWARQLFRRIQEPMKRFKEELGLLKHAE-GKKVIKKYNELAKKLDEY 429

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 614712334   81 TKMLLDKWIVECWQGIQQDIILTLLVKDEANK--LRVNFTERLIFALKDIKVVRLLSCDVSVNLTKFFCREDE 151
Cdd:pfam08385 430 ERLIYEAWLKEVEEASEGNLKRPLLVRHPETGklLSVNFDPQLLALLREVKYLQKLGFEIPESALNIALKEER 502
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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