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Conserved domains on  [gi|613410243|ref|NP_001278410|]
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midkine isoform a precursor [Mus musculus]

Protein Classification

PTN domain-containing protein( domain architecture ID 10640840)

PTN domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTN smart00193
Pleiotrophin / midkine family; Heparin-binding domain family.
 34-113 3.69e-45

Pleiotrophin / midkine family; Heparin-binding domain family.


:

Pssm-ID: 128490  Cd Length: 80  Bit Score: 141.94  E-value: 3.69e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613410243    34 CSEWTWGPCTPSSKDCGMGFREGTCGAQTQRVHCKVPCNWKKEFGADCKYKFESWGACDGSTGTKARQGTLKKARYNAQC 113
Cdd:smart00193   1 CGEWQWGPCIPNSKDCGLGTREGTCGQETRKLKCKIPCNWKKQFGADCKYKFESWGECDANTGLKTRSGTLKKALYNADC 80
 
Name Accession Description Interval E-value
PTN smart00193
Pleiotrophin / midkine family; Heparin-binding domain family.
 34-113 3.69e-45

Pleiotrophin / midkine family; Heparin-binding domain family.


Pssm-ID: 128490  Cd Length: 80  Bit Score: 141.94  E-value: 3.69e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613410243    34 CSEWTWGPCTPSSKDCGMGFREGTCGAQTQRVHCKVPCNWKKEFGADCKYKFESWGACDGSTGTKARQGTLKKARYNAQC 113
Cdd:smart00193   1 CGEWQWGPCIPNSKDCGLGTREGTCGQETRKLKCKIPCNWKKQFGADCKYKFESWGECDANTGLKTRSGTLKKALYNADC 80
PTN_MK_N pfam05196
PTN/MK heparin-binding protein family, N-terminal domain;
31-77 8.32e-22

PTN/MK heparin-binding protein family, N-terminal domain;


Pssm-ID: 461582  Cd Length: 57  Bit Score: 82.12  E-value: 8.32e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 613410243   31 GSECSEWTWGPCTPSSKDCGMGFREGTCGAQTQRVHCKVPCNWKKEF 77
Cdd:pfam05196  11 GSDCAEWQWGKCVPNSGDCGLGFREGTCKEQTKKIKCKIPCNWKKEF 57
 
Name Accession Description Interval E-value
PTN smart00193
Pleiotrophin / midkine family; Heparin-binding domain family.
 34-113 3.69e-45

Pleiotrophin / midkine family; Heparin-binding domain family.


Pssm-ID: 128490  Cd Length: 80  Bit Score: 141.94  E-value: 3.69e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613410243    34 CSEWTWGPCTPSSKDCGMGFREGTCGAQTQRVHCKVPCNWKKEFGADCKYKFESWGACDGSTGTKARQGTLKKARYNAQC 113
Cdd:smart00193   1 CGEWQWGPCIPNSKDCGLGTREGTCGQETRKLKCKIPCNWKKQFGADCKYKFESWGECDANTGLKTRSGTLKKALYNADC 80
PTN_MK_N pfam05196
PTN/MK heparin-binding protein family, N-terminal domain;
31-77 8.32e-22

PTN/MK heparin-binding protein family, N-terminal domain;


Pssm-ID: 461582  Cd Length: 57  Bit Score: 82.12  E-value: 8.32e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 613410243   31 GSECSEWTWGPCTPSSKDCGMGFREGTCGAQTQRVHCKVPCNWKKEF 77
Cdd:pfam05196  11 GSDCAEWQWGKCVPNSGDCGLGFREGTCKEQTKKIKCKIPCNWKKEF 57
PTN_MK_C pfam01091
PTN/MK heparin-binding protein family, C-terminal domain;
78-123 7.66e-19

PTN/MK heparin-binding protein family, C-terminal domain;


Pssm-ID: 460059  Cd Length: 65  Bit Score: 74.79  E-value: 7.66e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 613410243   78 GADCKYKFESWGACDGSTGTKARQGTLKKARYNAQCQETIRVTKPC 123
Cdd:pfam01091   1 GADCKYKFGAWGECDPATGTKTRTGTLKKALFNAECQQTVSVTKPC 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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