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Conserved domains on  [gi|607235393|gb|AHW46357|]
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RNA-dependent RNA polymerase [Mammarenavirus tacaribeense]

Protein Classification

ArenaCapSnatch and Arena_RNA_pol domain-containing protein( domain architecture ID 13879651)

ArenaCapSnatch and Arena_RNA_pol domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Arena_RNA_pol super family cl38204
Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins ...
 179-2205 0e+00

Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins (EC:2.7.7.48).


The actual alignment was detected with superfamily member pfam06317:

Pssm-ID: 399372  Cd Length: 2039  Bit Score: 3049.47  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   179 IEDQEYQRLIHSLSNVRNQSLGFENIECLKRNLLEYDDRLAKSLFVGVKGDVRESVIREELMKLRLWYKKEVFDKNL-GK 257
Cdd:pfam06317    1 FEESEYSRLCESLSMTSGRLSGVESLNCLKDNRSNHYDEVIASCHQGINNKLTAHEVKLQIEELYQVFRNRLRKGELeGQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   258 FRITNRSELLNNLIRLgkHEDNTTSDcpfcvnkfmDIIYSLTFTALKR-----------QDREKSNSELdqyvvcpHEKA 326
Cdd:pfam06317   81 FLKVNKSQLLNELNNL--YEDKVTSD---------DIIEHLTFQAKRAspilrflyantQDRERGNSTI-------GECQ 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   327 YLGVLSICNKIKGLKVFNTRRNTLLFLD-LIMVNFLDDLFtaKPEALDSLRRSGLILGQMVTLVNDRALDFlEAVKlikk 405
Cdd:pfam06317  143 YQCWLSFLNKVKSLKILNTRRKLLLILDaLILLASKHDLF--KQKALKGLRRSGLWLGQCFTSVNDRLVSF-EATK---- 215

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   406 kiETNVKWVQN--CSKILRR-SQQDIWSQIsvwarypdLSKLISIAQT------ISSDR--------------------- 455
Cdd:pfam06317  216 --EDLVKWVENrkRSKILRSvSKNQILNSI--------FSKTISKAQTalldvgISVDHykidmevichipydlimdfdv 285

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   456 ----PIMRYSaggnfntECKHKTFHMMSDAEQ---VEAFKILSSVSLSLINSMKTSFSSRLLINEKEYSRYfGNVRLREC 528
Cdd:pfam06317  286 sgvhPIMSYQ-------RTKEETFPYMMGDEQllnTTDLERLSSVSLALVNSMKTSSTVRLRQNEFGPARY-QVVRCKEA 357

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   529 YQQRFFLtDGLIVILFYQKTGERSRCYSIYTCEDGVLVekgSFYCDPKRFFLPIFSQEVLVEMCDEMTTWLDFNSDL--- 605
Cdd:pfam06317  358 YCQEFSL-DGTEVQLIYQKTGECSKCYSINDNEDGELC---SFYADPKRFFLPIFSAEVLQTMIDTMISWIEDCNDLedq 433

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   606 MVISKEKLRLLLLSILCAPSKRNQVFLQGLRYFLMAYSNQFHHVDLLSKLKVECMSGSEVIVQRLAVDLFQCLLGEGVDS 685
Cdd:pfam06317  434 LVIIRSLLRMLLLLILAHPSKRNQKLLQNLRYFVMAYVSDFHHKDLIDKLREELITDVEFLVYRLLRTLMQLVLGEGVKS 513

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   686 dpYFARRFKYLLNVSYLCHLITKETPDRLTDQIKCFEKFIEPKIDFNCVIVNPSlnGQLTEAQEGMMLDGLDKFYSKTLk 765
Cdd:pfam06317  514 --MMTNRFKFILNVSYLCHLITKETPDRLTDQIKCFEKFLEPKVDFGHVSVNPA--DTATEEEEDDMVYNAKKFLSKTL- 588

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   766 DCSDTKLPGVSKELLSYCISLFNKGKLKVTGELKNDPFKPNITS--TALDLSSNKSVVVPKLDELGNVLSvYDREKMISS 843
Cdd:pfam06317  589 DCTDYKLPGVSKEYLSLLTSSFNNGSLFKEGEVKNEIKDPLITSgsTALDLASNKSVVVNKYTDGSRVLN-YDFNKLTAS 667

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   844 CVSSMAERFKTKGRYNIDPSTLDYLILKNLTGLV--SIGSKTQRDCEELS-MMFEGltEEQAEAFNDIKNSVQLAMVKMK 920
Cdd:pfam06317  668 AVSQLTEVFSRKGKYLLNKSDYEYKVQKAMSNLVigSKQEKTDRDEADLDeILFDG--LEASEYFNQLKETVEKIVDQYR 745

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   921 DSKSGdvnLSPNQKEGRVKSSTGTLEEL----WGPFGIMREIKTEVSLHEVKDFDPDVLASDLYKELCDVVYYSSS-KPE 995
Cdd:pfam06317  746 EPVKG---GSGNNGDGRVKSSTPSLNDLdeivSGKFGYIRLIKGELSNHMVEDFDPDVLPSDFYKEFCDAVYESSSlKPK 822

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   996 YFLERPLEVCPLGLLLKNLTTSAYFDEEYFECFKYLLIQGHYDQKLGSYEHRSRSRLGFTNEALRVKDEVRLSMRESNSE 1075
Cdd:pfam06317  823 YFYCGHMSQCPLGELTKNLSTRTYFDHEYFQCFKSILLQMNANALMGKYTHYKRRNLNFKFDMGKLSDDVRISERESNSE 902

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1076 AIADKLDRSYFTNAALRNLCFYSDDSPTEFTSISSNNGNLKFGLSYKEQVGSNRELYVGDLNTKLITRLVEDFAEAVGSS 1155
Cdd:pfam06317  903 ALSKALSLTNCTTAALKNLCFYSQESPTSYTSVGPDTGRLKFSLSYKEQVGGNRELYIGDLRTKMFTRLIEDYFEAVSSQ 982

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1156 MRYTCLNSEKEFDRAICDMKLAVNNGDLSCSLDHSKWGPTMSPALFLTFLQFLELRTPKERNIIN-LEPVLNVLRWHLHK 1234
Cdd:pfam06317  983 LSGSCLNNEKEFENAILSMKLNVSNGHLSYSMDHSKWGPMMCPFLFLTFLQNLILLSKDLQADIKgRDYVSTLLMWHMHK 1062

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1235 VIEVPVNVAEAYCTGNLKRSLGLMGCGSSSVGEEFFHQFMQVqGEIPSHIMSVLDMGQGILHNMSDLYGLITEQFLNYVL 1314
Cdd:pfam06317 1063 MVEVPFNVVEAMMKSFIKAQLGLRKKTKQSVTEDFFYQNFQV-GVVPSHISSILDMGQGILHNTSDFYGLITERFINYAI 1141

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1315 DLLYDVIPTSYTSSDDQVTLIklpcasdDNQVND-------EWLEMLCFHEYLSSKLNKFVSPKSVAGTFVAEFKSRFFV 1387
Cdd:pfam06317 1142 SCICGGTPDAYTSSDDQITLF-------DQQLTDllvrdpeEFLELLEFHYYLSDQLNKFVSPKSVAGRFVAEFKSRFFV 1214

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1388 MGEETPLLTKFVAAALHNVKCKTPTQLSETIDTICDQCVANGVSVQIVSKISQRVNQLIKYSGFKETPFGAVEKQDVKDW 1467
Cdd:pfam06317 1215 WGEEVPLLTKFVAAALHNVKCKEPHQLAETIDTICDQSVANGVPVHLVNLIQQRTLQLLKYARFPIDPFLLNCETDVKDW 1294

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1468 VDGTRGYRLQRKIESIFSDDemTGFIRSCAKRVFNDIKRGKVFEENLISLIGRGGDDA---LVGFLRYSSCSEQDIMRAL 1544
Cdd:pfam06317 1295 VDGNRGYRIQRQIEGLIPDA--TSKIRSMLRRLYNRLKTGQLHEEFTTNLLSRDHLSAllnLCELLGVEPPSESDLMRAL 1372

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1545 GFRWVNLSSFGDLRLVLRTKLMTSRRV-LEREEVPTLIKTLQSRLSRNFTKGVKKILAESINKSAFQSSVASGFIGFCKS 1623
Cdd:pfam06317 1373 EYSWLNLAAHHPLRMVLRQKIIYSGAVnLDDEKIPTLIKTLQNKLSSTFTRGAQKLLSEAINKSAFQSSIASGFIGLCKT 1452

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1624 MGSKCVRDGEGGFLYIK---DIYTKVKPcLCEVCNmKRGVIYCRPSLE------KIEKFSKPILWDYFSLVLTNACEIGE 1694
Cdd:pfam06317 1453 LGSKCVRGPNKENLYIKsiqDLITDVKG-ICLVCN-SRGVQYWRVPLElrneseSIVSYFRPLLWDYMCISLSNAIELGA 1530

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1695 WVFSsvkEPQIPVVLS----NRNLFWAVKPRIVRQLEDQLGMNHVLYSIRKNYPKLFDEHLSPFMSDLQVNRTLDGRKLK 1770
Cdd:pfam06317 1531 WVLG---EPKTPKVLSffkhNPCDYFALKPTASRLLEDRVGLNHVIHSLRRLYPKVFEKHLLPFMSDLASTKMKWSPRIK 1607

                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1771 FLDVCIALDLMNENLGIVSHLLKARDNSVYIVKQSDCAMAHVRQSDYVDKEVGLSPQQVCYNFMVQIILSSMVNPLVMST 1850
Cdd:pfam06317 1608 FLDLCVALDVNCEALSLVSHIVKWKREEHYIVLSSDLAMSHVRTHEPMVEERVVSTSDVCDNFMRQIYFESYVRPFVATT 1687

                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1851 SCLKSFFWF-NEVLELEDDGQIELGELTDFTFLVRDQKISRAMFIEDIAMGY--VISNLEDVRLYIDKITigEQPLAPGR 1927
Cdd:pfam06317 1688 RTLGSFTWFpHKTSEPEGDGLHRLGPFSSFVEKVIHKGVERPMFKHDLMMGYawIDFDIEDVRFNQNQLI--AQGLVDPK 1765

                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1928 HINDLLDLLGNFDDHEDCDLRFLIQVEHSRTSTKYRFKRKMTYSFSVTCvskviDLKEASVELqVVDVTQSVSGSGGSHL 2007
Cdd:pfam06317 1766 HFDSLEDLFDAVASLPDGSLKFSITVRFRRKSQDASFKRKFAIHFSVTC-----SLNQQAVYL-VHDVTQMYSGAVSPCV 1839

                         1930      1940      1950      1960      1970      1980      1990      2000
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  2008 LLDGVSMIAGLPIFTGQGTFNMASLMMDADLVETNDN-------LILTDVRFSFggflselsDKYAYTLNGPVDQGEPLV 2080
Cdd:pfam06317 1840 LSDCWRLVLSGPTFKGKGVFYVDSEMINEFLVDTNQLghvtpveLILDMERLQF--------DEYDFTLVGPCDEPVPLV 1911

                         2010      2020      2030      2040      2050      2060      2070      2080
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  2081 LRDGHFFMGTEKVSTYRVELTGDIIVKAIGALDDPEDVNALLNQLWPYLKSTAQVMLFQQEDFV---LVYDLHRSGLIRS 2157
Cdd:pfam06317 1912 VRRGGLFEGTKKVASFTVVLQDQDLEKFVRELGDPEDVNALLNQLWPYLKTTSDLLLGALSDMIldrLGLDMHRSGLSAV 1991

                         2090      2100      2110      2120
                   ....*....|....*....|....*....|....*....|....*...
gi 607235393  2158 LELIGDWVEFVNFKVAYSKSLKDLVVSDNQGSLRLRGIMCRPLARRNT 2205
Cdd:pfam06317 1992 LELVDDWVEFKGYALCYSKSRGDLMVQSSGGKLRLKGRTCEELTRGNE 2039
ArenaCapSnatch pfam17296
Arenavirus cap snatching domain; This domain represents the N-terminal domain of the ...
 2-172 5.84e-99

Arenavirus cap snatching domain; This domain represents the N-terminal domain of the Arenavirus polymerase that is involved in cap snatching during transcription initiation.


:

Pssm-ID: 340012  Cd Length: 171  Bit Score: 315.63  E-value: 5.84e-99
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393     2 DETVSELKDLVRKHIPNRHEFAHQKDAFLSQCHSGSLLQEGFKLLSNLVELESCESHACHLNTCQKYVDVILSDHGIPCP 81
Cdd:pfam17296    1 DETISELKDLVRKYIPNRERLSRQKLAFLSQCEPRMLLQEGLKLLSNCIELDSCESHGCHHNTCDKSVEVILSDHGIPCP 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393    82 TLPKVIPDGFKLTGKTLILLETFVRVNPEEFERKWKSDMTKLLNLKQDLLRSGITLVPVVDGRTNYSNRFTPEWVVERIR 161
Cdd:pfam17296   81 TLPLVIPDGYKLTGNTLILLECFVRSNPAEFERKWIEDMTKLLNLKEDLLRSGITLVPVVDGRTNYSNRFTPEWVNEKIR 160

                          170
                   ....*....|.
gi 607235393   162 WLLIEILRKSR 172
Cdd:pfam17296  161 DLLFELLRYSR 171
 
Name Accession Description Interval E-value
Arena_RNA_pol pfam06317
Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins ...
 179-2205 0e+00

Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins (EC:2.7.7.48).


Pssm-ID: 399372  Cd Length: 2039  Bit Score: 3049.47  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   179 IEDQEYQRLIHSLSNVRNQSLGFENIECLKRNLLEYDDRLAKSLFVGVKGDVRESVIREELMKLRLWYKKEVFDKNL-GK 257
Cdd:pfam06317    1 FEESEYSRLCESLSMTSGRLSGVESLNCLKDNRSNHYDEVIASCHQGINNKLTAHEVKLQIEELYQVFRNRLRKGELeGQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   258 FRITNRSELLNNLIRLgkHEDNTTSDcpfcvnkfmDIIYSLTFTALKR-----------QDREKSNSELdqyvvcpHEKA 326
Cdd:pfam06317   81 FLKVNKSQLLNELNNL--YEDKVTSD---------DIIEHLTFQAKRAspilrflyantQDRERGNSTI-------GECQ 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   327 YLGVLSICNKIKGLKVFNTRRNTLLFLD-LIMVNFLDDLFtaKPEALDSLRRSGLILGQMVTLVNDRALDFlEAVKlikk 405
Cdd:pfam06317  143 YQCWLSFLNKVKSLKILNTRRKLLLILDaLILLASKHDLF--KQKALKGLRRSGLWLGQCFTSVNDRLVSF-EATK---- 215

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   406 kiETNVKWVQN--CSKILRR-SQQDIWSQIsvwarypdLSKLISIAQT------ISSDR--------------------- 455
Cdd:pfam06317  216 --EDLVKWVENrkRSKILRSvSKNQILNSI--------FSKTISKAQTalldvgISVDHykidmevichipydlimdfdv 285

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   456 ----PIMRYSaggnfntECKHKTFHMMSDAEQ---VEAFKILSSVSLSLINSMKTSFSSRLLINEKEYSRYfGNVRLREC 528
Cdd:pfam06317  286 sgvhPIMSYQ-------RTKEETFPYMMGDEQllnTTDLERLSSVSLALVNSMKTSSTVRLRQNEFGPARY-QVVRCKEA 357

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   529 YQQRFFLtDGLIVILFYQKTGERSRCYSIYTCEDGVLVekgSFYCDPKRFFLPIFSQEVLVEMCDEMTTWLDFNSDL--- 605
Cdd:pfam06317  358 YCQEFSL-DGTEVQLIYQKTGECSKCYSINDNEDGELC---SFYADPKRFFLPIFSAEVLQTMIDTMISWIEDCNDLedq 433

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   606 MVISKEKLRLLLLSILCAPSKRNQVFLQGLRYFLMAYSNQFHHVDLLSKLKVECMSGSEVIVQRLAVDLFQCLLGEGVDS 685
Cdd:pfam06317  434 LVIIRSLLRMLLLLILAHPSKRNQKLLQNLRYFVMAYVSDFHHKDLIDKLREELITDVEFLVYRLLRTLMQLVLGEGVKS 513

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   686 dpYFARRFKYLLNVSYLCHLITKETPDRLTDQIKCFEKFIEPKIDFNCVIVNPSlnGQLTEAQEGMMLDGLDKFYSKTLk 765
Cdd:pfam06317  514 --MMTNRFKFILNVSYLCHLITKETPDRLTDQIKCFEKFLEPKVDFGHVSVNPA--DTATEEEEDDMVYNAKKFLSKTL- 588

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   766 DCSDTKLPGVSKELLSYCISLFNKGKLKVTGELKNDPFKPNITS--TALDLSSNKSVVVPKLDELGNVLSvYDREKMISS 843
Cdd:pfam06317  589 DCTDYKLPGVSKEYLSLLTSSFNNGSLFKEGEVKNEIKDPLITSgsTALDLASNKSVVVNKYTDGSRVLN-YDFNKLTAS 667

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   844 CVSSMAERFKTKGRYNIDPSTLDYLILKNLTGLV--SIGSKTQRDCEELS-MMFEGltEEQAEAFNDIKNSVQLAMVKMK 920
Cdd:pfam06317  668 AVSQLTEVFSRKGKYLLNKSDYEYKVQKAMSNLVigSKQEKTDRDEADLDeILFDG--LEASEYFNQLKETVEKIVDQYR 745

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   921 DSKSGdvnLSPNQKEGRVKSSTGTLEEL----WGPFGIMREIKTEVSLHEVKDFDPDVLASDLYKELCDVVYYSSS-KPE 995
Cdd:pfam06317  746 EPVKG---GSGNNGDGRVKSSTPSLNDLdeivSGKFGYIRLIKGELSNHMVEDFDPDVLPSDFYKEFCDAVYESSSlKPK 822

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   996 YFLERPLEVCPLGLLLKNLTTSAYFDEEYFECFKYLLIQGHYDQKLGSYEHRSRSRLGFTNEALRVKDEVRLSMRESNSE 1075
Cdd:pfam06317  823 YFYCGHMSQCPLGELTKNLSTRTYFDHEYFQCFKSILLQMNANALMGKYTHYKRRNLNFKFDMGKLSDDVRISERESNSE 902

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1076 AIADKLDRSYFTNAALRNLCFYSDDSPTEFTSISSNNGNLKFGLSYKEQVGSNRELYVGDLNTKLITRLVEDFAEAVGSS 1155
Cdd:pfam06317  903 ALSKALSLTNCTTAALKNLCFYSQESPTSYTSVGPDTGRLKFSLSYKEQVGGNRELYIGDLRTKMFTRLIEDYFEAVSSQ 982

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1156 MRYTCLNSEKEFDRAICDMKLAVNNGDLSCSLDHSKWGPTMSPALFLTFLQFLELRTPKERNIIN-LEPVLNVLRWHLHK 1234
Cdd:pfam06317  983 LSGSCLNNEKEFENAILSMKLNVSNGHLSYSMDHSKWGPMMCPFLFLTFLQNLILLSKDLQADIKgRDYVSTLLMWHMHK 1062

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1235 VIEVPVNVAEAYCTGNLKRSLGLMGCGSSSVGEEFFHQFMQVqGEIPSHIMSVLDMGQGILHNMSDLYGLITEQFLNYVL 1314
Cdd:pfam06317 1063 MVEVPFNVVEAMMKSFIKAQLGLRKKTKQSVTEDFFYQNFQV-GVVPSHISSILDMGQGILHNTSDFYGLITERFINYAI 1141

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1315 DLLYDVIPTSYTSSDDQVTLIklpcasdDNQVND-------EWLEMLCFHEYLSSKLNKFVSPKSVAGTFVAEFKSRFFV 1387
Cdd:pfam06317 1142 SCICGGTPDAYTSSDDQITLF-------DQQLTDllvrdpeEFLELLEFHYYLSDQLNKFVSPKSVAGRFVAEFKSRFFV 1214

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1388 MGEETPLLTKFVAAALHNVKCKTPTQLSETIDTICDQCVANGVSVQIVSKISQRVNQLIKYSGFKETPFGAVEKQDVKDW 1467
Cdd:pfam06317 1215 WGEEVPLLTKFVAAALHNVKCKEPHQLAETIDTICDQSVANGVPVHLVNLIQQRTLQLLKYARFPIDPFLLNCETDVKDW 1294

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1468 VDGTRGYRLQRKIESIFSDDemTGFIRSCAKRVFNDIKRGKVFEENLISLIGRGGDDA---LVGFLRYSSCSEQDIMRAL 1544
Cdd:pfam06317 1295 VDGNRGYRIQRQIEGLIPDA--TSKIRSMLRRLYNRLKTGQLHEEFTTNLLSRDHLSAllnLCELLGVEPPSESDLMRAL 1372

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1545 GFRWVNLSSFGDLRLVLRTKLMTSRRV-LEREEVPTLIKTLQSRLSRNFTKGVKKILAESINKSAFQSSVASGFIGFCKS 1623
Cdd:pfam06317 1373 EYSWLNLAAHHPLRMVLRQKIIYSGAVnLDDEKIPTLIKTLQNKLSSTFTRGAQKLLSEAINKSAFQSSIASGFIGLCKT 1452

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1624 MGSKCVRDGEGGFLYIK---DIYTKVKPcLCEVCNmKRGVIYCRPSLE------KIEKFSKPILWDYFSLVLTNACEIGE 1694
Cdd:pfam06317 1453 LGSKCVRGPNKENLYIKsiqDLITDVKG-ICLVCN-SRGVQYWRVPLElrneseSIVSYFRPLLWDYMCISLSNAIELGA 1530

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1695 WVFSsvkEPQIPVVLS----NRNLFWAVKPRIVRQLEDQLGMNHVLYSIRKNYPKLFDEHLSPFMSDLQVNRTLDGRKLK 1770
Cdd:pfam06317 1531 WVLG---EPKTPKVLSffkhNPCDYFALKPTASRLLEDRVGLNHVIHSLRRLYPKVFEKHLLPFMSDLASTKMKWSPRIK 1607

                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1771 FLDVCIALDLMNENLGIVSHLLKARDNSVYIVKQSDCAMAHVRQSDYVDKEVGLSPQQVCYNFMVQIILSSMVNPLVMST 1850
Cdd:pfam06317 1608 FLDLCVALDVNCEALSLVSHIVKWKREEHYIVLSSDLAMSHVRTHEPMVEERVVSTSDVCDNFMRQIYFESYVRPFVATT 1687

                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1851 SCLKSFFWF-NEVLELEDDGQIELGELTDFTFLVRDQKISRAMFIEDIAMGY--VISNLEDVRLYIDKITigEQPLAPGR 1927
Cdd:pfam06317 1688 RTLGSFTWFpHKTSEPEGDGLHRLGPFSSFVEKVIHKGVERPMFKHDLMMGYawIDFDIEDVRFNQNQLI--AQGLVDPK 1765

                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1928 HINDLLDLLGNFDDHEDCDLRFLIQVEHSRTSTKYRFKRKMTYSFSVTCvskviDLKEASVELqVVDVTQSVSGSGGSHL 2007
Cdd:pfam06317 1766 HFDSLEDLFDAVASLPDGSLKFSITVRFRRKSQDASFKRKFAIHFSVTC-----SLNQQAVYL-VHDVTQMYSGAVSPCV 1839

                         1930      1940      1950      1960      1970      1980      1990      2000
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  2008 LLDGVSMIAGLPIFTGQGTFNMASLMMDADLVETNDN-------LILTDVRFSFggflselsDKYAYTLNGPVDQGEPLV 2080
Cdd:pfam06317 1840 LSDCWRLVLSGPTFKGKGVFYVDSEMINEFLVDTNQLghvtpveLILDMERLQF--------DEYDFTLVGPCDEPVPLV 1911

                         2010      2020      2030      2040      2050      2060      2070      2080
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  2081 LRDGHFFMGTEKVSTYRVELTGDIIVKAIGALDDPEDVNALLNQLWPYLKSTAQVMLFQQEDFV---LVYDLHRSGLIRS 2157
Cdd:pfam06317 1912 VRRGGLFEGTKKVASFTVVLQDQDLEKFVRELGDPEDVNALLNQLWPYLKTTSDLLLGALSDMIldrLGLDMHRSGLSAV 1991

                         2090      2100      2110      2120
                   ....*....|....*....|....*....|....*....|....*...
gi 607235393  2158 LELIGDWVEFVNFKVAYSKSLKDLVVSDNQGSLRLRGIMCRPLARRNT 2205
Cdd:pfam06317 1992 LELVDDWVEFKGYALCYSKSRGDLMVQSSGGKLRLKGRTCEELTRGNE 2039
ArenaCapSnatch pfam17296
Arenavirus cap snatching domain; This domain represents the N-terminal domain of the ...
 2-172 5.84e-99

Arenavirus cap snatching domain; This domain represents the N-terminal domain of the Arenavirus polymerase that is involved in cap snatching during transcription initiation.


Pssm-ID: 340012  Cd Length: 171  Bit Score: 315.63  E-value: 5.84e-99
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393     2 DETVSELKDLVRKHIPNRHEFAHQKDAFLSQCHSGSLLQEGFKLLSNLVELESCESHACHLNTCQKYVDVILSDHGIPCP 81
Cdd:pfam17296    1 DETISELKDLVRKYIPNRERLSRQKLAFLSQCEPRMLLQEGLKLLSNCIELDSCESHGCHHNTCDKSVEVILSDHGIPCP 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393    82 TLPKVIPDGFKLTGKTLILLETFVRVNPEEFERKWKSDMTKLLNLKQDLLRSGITLVPVVDGRTNYSNRFTPEWVVERIR 161
Cdd:pfam17296   81 TLPLVIPDGYKLTGNTLILLECFVRSNPAEFERKWIEDMTKLLNLKEDLLRSGITLVPVVDGRTNYSNRFTPEWVNEKIR 160

                          170
                   ....*....|.
gi 607235393   162 WLLIEILRKSR 172
Cdd:pfam17296  161 DLLFELLRYSR 171
capSnatchArena TIGR04202
RNA endonuclease, cap-snatching, arenavirus family; This model describes a shared signature ...
 86-146 3.26e-27

RNA endonuclease, cap-snatching, arenavirus family; This model describes a shared signature region from an RNA endonuclease region associated with cap-snatching for mRNA production by RNA viruses. This domain usually is part of a multifunctional protein, the L protein responsible for RNA-dependent RNA polymerase activity. Cap-snatching is a viral alternative to synthesizing a eukaryotic-like mRNA cap itself.


Pssm-ID: 275049  Cd Length: 61  Bit Score: 106.13  E-value: 3.26e-27
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 607235393    86 VIPDGFKLTGKTLILLETFVRVNPEEFERKWKSDMTKLLNLKQDLLRSGITLVPVVDGRTN 146
Cdd:TIGR04202    1 VTPDNYKLTGNVLILLEVFVRVDPESFEKKYKEKYEKLLSLKGDLLSPGITLVPVVDGRTD 61
 
Name Accession Description Interval E-value
Arena_RNA_pol pfam06317
Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins ...
 179-2205 0e+00

Arenavirus RNA polymerase; This family consists of several Arenavirus RNA polymerase proteins (EC:2.7.7.48).


Pssm-ID: 399372  Cd Length: 2039  Bit Score: 3049.47  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   179 IEDQEYQRLIHSLSNVRNQSLGFENIECLKRNLLEYDDRLAKSLFVGVKGDVRESVIREELMKLRLWYKKEVFDKNL-GK 257
Cdd:pfam06317    1 FEESEYSRLCESLSMTSGRLSGVESLNCLKDNRSNHYDEVIASCHQGINNKLTAHEVKLQIEELYQVFRNRLRKGELeGQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   258 FRITNRSELLNNLIRLgkHEDNTTSDcpfcvnkfmDIIYSLTFTALKR-----------QDREKSNSELdqyvvcpHEKA 326
Cdd:pfam06317   81 FLKVNKSQLLNELNNL--YEDKVTSD---------DIIEHLTFQAKRAspilrflyantQDRERGNSTI-------GECQ 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   327 YLGVLSICNKIKGLKVFNTRRNTLLFLD-LIMVNFLDDLFtaKPEALDSLRRSGLILGQMVTLVNDRALDFlEAVKlikk 405
Cdd:pfam06317  143 YQCWLSFLNKVKSLKILNTRRKLLLILDaLILLASKHDLF--KQKALKGLRRSGLWLGQCFTSVNDRLVSF-EATK---- 215

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   406 kiETNVKWVQN--CSKILRR-SQQDIWSQIsvwarypdLSKLISIAQT------ISSDR--------------------- 455
Cdd:pfam06317  216 --EDLVKWVENrkRSKILRSvSKNQILNSI--------FSKTISKAQTalldvgISVDHykidmevichipydlimdfdv 285

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   456 ----PIMRYSaggnfntECKHKTFHMMSDAEQ---VEAFKILSSVSLSLINSMKTSFSSRLLINEKEYSRYfGNVRLREC 528
Cdd:pfam06317  286 sgvhPIMSYQ-------RTKEETFPYMMGDEQllnTTDLERLSSVSLALVNSMKTSSTVRLRQNEFGPARY-QVVRCKEA 357

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   529 YQQRFFLtDGLIVILFYQKTGERSRCYSIYTCEDGVLVekgSFYCDPKRFFLPIFSQEVLVEMCDEMTTWLDFNSDL--- 605
Cdd:pfam06317  358 YCQEFSL-DGTEVQLIYQKTGECSKCYSINDNEDGELC---SFYADPKRFFLPIFSAEVLQTMIDTMISWIEDCNDLedq 433

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   606 MVISKEKLRLLLLSILCAPSKRNQVFLQGLRYFLMAYSNQFHHVDLLSKLKVECMSGSEVIVQRLAVDLFQCLLGEGVDS 685
Cdd:pfam06317  434 LVIIRSLLRMLLLLILAHPSKRNQKLLQNLRYFVMAYVSDFHHKDLIDKLREELITDVEFLVYRLLRTLMQLVLGEGVKS 513

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   686 dpYFARRFKYLLNVSYLCHLITKETPDRLTDQIKCFEKFIEPKIDFNCVIVNPSlnGQLTEAQEGMMLDGLDKFYSKTLk 765
Cdd:pfam06317  514 --MMTNRFKFILNVSYLCHLITKETPDRLTDQIKCFEKFLEPKVDFGHVSVNPA--DTATEEEEDDMVYNAKKFLSKTL- 588

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   766 DCSDTKLPGVSKELLSYCISLFNKGKLKVTGELKNDPFKPNITS--TALDLSSNKSVVVPKLDELGNVLSvYDREKMISS 843
Cdd:pfam06317  589 DCTDYKLPGVSKEYLSLLTSSFNNGSLFKEGEVKNEIKDPLITSgsTALDLASNKSVVVNKYTDGSRVLN-YDFNKLTAS 667

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   844 CVSSMAERFKTKGRYNIDPSTLDYLILKNLTGLV--SIGSKTQRDCEELS-MMFEGltEEQAEAFNDIKNSVQLAMVKMK 920
Cdd:pfam06317  668 AVSQLTEVFSRKGKYLLNKSDYEYKVQKAMSNLVigSKQEKTDRDEADLDeILFDG--LEASEYFNQLKETVEKIVDQYR 745

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   921 DSKSGdvnLSPNQKEGRVKSSTGTLEEL----WGPFGIMREIKTEVSLHEVKDFDPDVLASDLYKELCDVVYYSSS-KPE 995
Cdd:pfam06317  746 EPVKG---GSGNNGDGRVKSSTPSLNDLdeivSGKFGYIRLIKGELSNHMVEDFDPDVLPSDFYKEFCDAVYESSSlKPK 822

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393   996 YFLERPLEVCPLGLLLKNLTTSAYFDEEYFECFKYLLIQGHYDQKLGSYEHRSRSRLGFTNEALRVKDEVRLSMRESNSE 1075
Cdd:pfam06317  823 YFYCGHMSQCPLGELTKNLSTRTYFDHEYFQCFKSILLQMNANALMGKYTHYKRRNLNFKFDMGKLSDDVRISERESNSE 902

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1076 AIADKLDRSYFTNAALRNLCFYSDDSPTEFTSISSNNGNLKFGLSYKEQVGSNRELYVGDLNTKLITRLVEDFAEAVGSS 1155
Cdd:pfam06317  903 ALSKALSLTNCTTAALKNLCFYSQESPTSYTSVGPDTGRLKFSLSYKEQVGGNRELYIGDLRTKMFTRLIEDYFEAVSSQ 982

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1156 MRYTCLNSEKEFDRAICDMKLAVNNGDLSCSLDHSKWGPTMSPALFLTFLQFLELRTPKERNIIN-LEPVLNVLRWHLHK 1234
Cdd:pfam06317  983 LSGSCLNNEKEFENAILSMKLNVSNGHLSYSMDHSKWGPMMCPFLFLTFLQNLILLSKDLQADIKgRDYVSTLLMWHMHK 1062

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1235 VIEVPVNVAEAYCTGNLKRSLGLMGCGSSSVGEEFFHQFMQVqGEIPSHIMSVLDMGQGILHNMSDLYGLITEQFLNYVL 1314
Cdd:pfam06317 1063 MVEVPFNVVEAMMKSFIKAQLGLRKKTKQSVTEDFFYQNFQV-GVVPSHISSILDMGQGILHNTSDFYGLITERFINYAI 1141

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1315 DLLYDVIPTSYTSSDDQVTLIklpcasdDNQVND-------EWLEMLCFHEYLSSKLNKFVSPKSVAGTFVAEFKSRFFV 1387
Cdd:pfam06317 1142 SCICGGTPDAYTSSDDQITLF-------DQQLTDllvrdpeEFLELLEFHYYLSDQLNKFVSPKSVAGRFVAEFKSRFFV 1214

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1388 MGEETPLLTKFVAAALHNVKCKTPTQLSETIDTICDQCVANGVSVQIVSKISQRVNQLIKYSGFKETPFGAVEKQDVKDW 1467
Cdd:pfam06317 1215 WGEEVPLLTKFVAAALHNVKCKEPHQLAETIDTICDQSVANGVPVHLVNLIQQRTLQLLKYARFPIDPFLLNCETDVKDW 1294

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1468 VDGTRGYRLQRKIESIFSDDemTGFIRSCAKRVFNDIKRGKVFEENLISLIGRGGDDA---LVGFLRYSSCSEQDIMRAL 1544
Cdd:pfam06317 1295 VDGNRGYRIQRQIEGLIPDA--TSKIRSMLRRLYNRLKTGQLHEEFTTNLLSRDHLSAllnLCELLGVEPPSESDLMRAL 1372

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1545 GFRWVNLSSFGDLRLVLRTKLMTSRRV-LEREEVPTLIKTLQSRLSRNFTKGVKKILAESINKSAFQSSVASGFIGFCKS 1623
Cdd:pfam06317 1373 EYSWLNLAAHHPLRMVLRQKIIYSGAVnLDDEKIPTLIKTLQNKLSSTFTRGAQKLLSEAINKSAFQSSIASGFIGLCKT 1452

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1624 MGSKCVRDGEGGFLYIK---DIYTKVKPcLCEVCNmKRGVIYCRPSLE------KIEKFSKPILWDYFSLVLTNACEIGE 1694
Cdd:pfam06317 1453 LGSKCVRGPNKENLYIKsiqDLITDVKG-ICLVCN-SRGVQYWRVPLElrneseSIVSYFRPLLWDYMCISLSNAIELGA 1530

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1695 WVFSsvkEPQIPVVLS----NRNLFWAVKPRIVRQLEDQLGMNHVLYSIRKNYPKLFDEHLSPFMSDLQVNRTLDGRKLK 1770
Cdd:pfam06317 1531 WVLG---EPKTPKVLSffkhNPCDYFALKPTASRLLEDRVGLNHVIHSLRRLYPKVFEKHLLPFMSDLASTKMKWSPRIK 1607

                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1771 FLDVCIALDLMNENLGIVSHLLKARDNSVYIVKQSDCAMAHVRQSDYVDKEVGLSPQQVCYNFMVQIILSSMVNPLVMST 1850
Cdd:pfam06317 1608 FLDLCVALDVNCEALSLVSHIVKWKREEHYIVLSSDLAMSHVRTHEPMVEERVVSTSDVCDNFMRQIYFESYVRPFVATT 1687

                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1851 SCLKSFFWF-NEVLELEDDGQIELGELTDFTFLVRDQKISRAMFIEDIAMGY--VISNLEDVRLYIDKITigEQPLAPGR 1927
Cdd:pfam06317 1688 RTLGSFTWFpHKTSEPEGDGLHRLGPFSSFVEKVIHKGVERPMFKHDLMMGYawIDFDIEDVRFNQNQLI--AQGLVDPK 1765

                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  1928 HINDLLDLLGNFDDHEDCDLRFLIQVEHSRTSTKYRFKRKMTYSFSVTCvskviDLKEASVELqVVDVTQSVSGSGGSHL 2007
Cdd:pfam06317 1766 HFDSLEDLFDAVASLPDGSLKFSITVRFRRKSQDASFKRKFAIHFSVTC-----SLNQQAVYL-VHDVTQMYSGAVSPCV 1839

                         1930      1940      1950      1960      1970      1980      1990      2000
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  2008 LLDGVSMIAGLPIFTGQGTFNMASLMMDADLVETNDN-------LILTDVRFSFggflselsDKYAYTLNGPVDQGEPLV 2080
Cdd:pfam06317 1840 LSDCWRLVLSGPTFKGKGVFYVDSEMINEFLVDTNQLghvtpveLILDMERLQF--------DEYDFTLVGPCDEPVPLV 1911

                         2010      2020      2030      2040      2050      2060      2070      2080
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393  2081 LRDGHFFMGTEKVSTYRVELTGDIIVKAIGALDDPEDVNALLNQLWPYLKSTAQVMLFQQEDFV---LVYDLHRSGLIRS 2157
Cdd:pfam06317 1912 VRRGGLFEGTKKVASFTVVLQDQDLEKFVRELGDPEDVNALLNQLWPYLKTTSDLLLGALSDMIldrLGLDMHRSGLSAV 1991

                         2090      2100      2110      2120
                   ....*....|....*....|....*....|....*....|....*...
gi 607235393  2158 LELIGDWVEFVNFKVAYSKSLKDLVVSDNQGSLRLRGIMCRPLARRNT 2205
Cdd:pfam06317 1992 LELVDDWVEFKGYALCYSKSRGDLMVQSSGGKLRLKGRTCEELTRGNE 2039
ArenaCapSnatch pfam17296
Arenavirus cap snatching domain; This domain represents the N-terminal domain of the ...
 2-172 5.84e-99

Arenavirus cap snatching domain; This domain represents the N-terminal domain of the Arenavirus polymerase that is involved in cap snatching during transcription initiation.


Pssm-ID: 340012  Cd Length: 171  Bit Score: 315.63  E-value: 5.84e-99
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393     2 DETVSELKDLVRKHIPNRHEFAHQKDAFLSQCHSGSLLQEGFKLLSNLVELESCESHACHLNTCQKYVDVILSDHGIPCP 81
Cdd:pfam17296    1 DETISELKDLVRKYIPNRERLSRQKLAFLSQCEPRMLLQEGLKLLSNCIELDSCESHGCHHNTCDKSVEVILSDHGIPCP 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 607235393    82 TLPKVIPDGFKLTGKTLILLETFVRVNPEEFERKWKSDMTKLLNLKQDLLRSGITLVPVVDGRTNYSNRFTPEWVVERIR 161
Cdd:pfam17296   81 TLPLVIPDGYKLTGNTLILLECFVRSNPAEFERKWIEDMTKLLNLKEDLLRSGITLVPVVDGRTNYSNRFTPEWVNEKIR 160

                          170
                   ....*....|.
gi 607235393   162 WLLIEILRKSR 172
Cdd:pfam17296  161 DLLFELLRYSR 171
capSnatchArena TIGR04202
RNA endonuclease, cap-snatching, arenavirus family; This model describes a shared signature ...
 86-146 3.26e-27

RNA endonuclease, cap-snatching, arenavirus family; This model describes a shared signature region from an RNA endonuclease region associated with cap-snatching for mRNA production by RNA viruses. This domain usually is part of a multifunctional protein, the L protein responsible for RNA-dependent RNA polymerase activity. Cap-snatching is a viral alternative to synthesizing a eukaryotic-like mRNA cap itself.


Pssm-ID: 275049  Cd Length: 61  Bit Score: 106.13  E-value: 3.26e-27
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 607235393    86 VIPDGFKLTGKTLILLETFVRVNPEEFERKWKSDMTKLLNLKQDLLRSGITLVPVVDGRTN 146
Cdd:TIGR04202    1 VTPDNYKLTGNVLILLEVFVRVDPESFEKKYKEKYEKLLSLKGDLLSPGITLVPVVDGRTD 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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