|
Name |
Accession |
Description |
Interval |
E-value |
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-850 |
0e+00 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 1914.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 1 MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVK 80
Cdd:PRK11636 1 MKFVKYLLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 81 AFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL 160
Cdd:PRK11636 81 AFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQF 240
Cdd:PRK11636 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 241 DQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPA 320
Cdd:PRK11636 241 DQARSEPIVANYHAPEIAFSAPYLSEMVRQEMYNRYGENAYEDGYRVYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 321 NVLWKVGESAWDNNKITDTLKALPTYGPLLPAAVTSANPQEATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVTD 400
Cdd:PRK11636 321 NVLWKVGESAWDNKKITDTLKALPTYGPLLPAVVTSANPQEATAMLADGSSVALPMEGVRWARPYRSDTQQGPTPRKVTD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 401 VLQTGQQIWVRQVGDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL 480
Cdd:PRK11636 401 VVQTGQQIWVRQVDDAWWLAQVPDVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 481 TLASMLNDVPISRWDAGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGFPAQNIVHTES 560
Cdd:PRK11636 481 TLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTES 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 561 LALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDTQKSNVLENNDVEDVAI 640
Cdd:PRK11636 561 LALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKVACPECDIPVIYGDTQKSNVLENDDVENVAT 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 641 SREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTT 720
Cdd:PRK11636 641 SQEQQNSSVPMPQLEQANQALVAQNGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWMGTGWRAGRDLKRRDIGGKTGTT 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 721 NSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPGIV 800
Cdd:PRK11636 721 NSSKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTASGAIKDQISGYEGGAKSAQPAWDDYMKAALEGVPEQPLTPPPGIV 800
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 585376740 801 TVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF 850
Cdd:PRK11636 801 TVNIDRSTGKLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGETHELF 850
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
1-850 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 1217.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 1 MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVK 80
Cdd:COG5009 1 MRLLKILLILLLLLLLLGALAVAGLYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLIN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 81 AFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL 160
Cdd:COG5009 81 AFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQF 240
Cdd:COG5009 161 ELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 241 DQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGE-SAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGP 319
Cdd:COG5009 241 EAAKAEPLTARYHGASAEVDAPYFAEMVRRELVERYGEdALYTGGLKVYTTLDPRLQEAAEKALRDGLLAYDRRHGYRGP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 320 ANVLWkVGESAWDnnkitDTLKALPTYGPLLPAAVTSANPQEATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVT 399
Cdd:COG5009 321 EAHLD-LAEEDWD-----EALAEVPDVGDLRPAVVLEVDDKSARVGLRDGETGTLPLEGLKWARPYINDNRRGPAPKSAS 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 400 DVLQTGQQIWVRQVGDA-WWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDK 478
Cdd:COG5009 395 DVLKPGDVIRVRPVADGgWRLRQIPEVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFVYAAALDN 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 479 GLTLASMLNDVPISRWDAGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGFPAQnIVHT 558
Cdd:COG5009 475 GYTPATIINDAPIVFDDGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIYSK-LPPN 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 559 ESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDipviygdtqksnvlenndvedv 638
Cdd:COG5009 554 LSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARACEDCD---------------------- 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 639 aisreQQNVSVPMPQLeqanqalvaktgaQEYAPHVINTPLAFLIKSALNTNIfgepgWQGTGWRAgRDLqRRDIGGKTG 718
Cdd:COG5009 612 -----AAEWDGAEPRL-------------PDPAEQVIDPRTAYQMTSMLRGVV-----QRGTGRRA-RAL-GRDIAGKTG 666
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 719 TTNSSKDAWFSGYGPGVVTSVWIGFDDHrRNLGHttasgaikdqisgYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG 798
Cdd:COG5009 667 TTNDSKDAWFVGFTPDLVAGVWVGFDDP-RSLGR-------------GETGGRAALPIWIDFMKAALKDKPEKPFPVPEG 732
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 585376740 799 IVTVNIDRSTGQLANGG--NSREEYFIEGTQPTQQAVHEVGTTiIDNGEAQELF 850
Cdd:COG5009 733 IVTVRIDPKTGLLASPGdpDAIFEAFKPGTEPTESASEDLGPD-ASEGTGEGLF 785
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
65-787 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 561.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 65 RRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEV 144
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 145 FLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNV 224
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 225 VLSRMLDEGYITQQQFDQTRTEAINANYHAP-EIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAV 303
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKkSEQYKAPYFVDYVIQELEEEYGEELYTGGLKIYTTLDLDAQKAAEKVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 304 RNNVLDYDMRHGYrgpanvlwkvgesawdnnkitdtlkalptygpllpaavtsanpqeatamladgstvalsmegvrwar 383
Cdd:TIGR02074 241 NTGLRVAGRRDGD------------------------------------------------------------------- 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 384 pyrsdtqqgptprkvtdvlqtgqqiwvrqvgdawwlaqvpEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQV 463
Cdd:TIGR02074 254 ----------------------------------------DLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQP 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 464 GSNIKPFLYTAAMDKGLTLASMLNDVPISrwdAGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAE 543
Cdd:TIGR02074 294 GSTFKPFVYAAALEKGLTPATIVNDEPIT---YNGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVA 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 544 YLQRFGFPAqNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKvacpecdipviygd 623
Cdd:TIGR02074 371 LAKRFGITS-PLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPK-------------- 435
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 624 tqksnvlenndvEDVAISREQQNVSVPMpqleqanqalvaktgaqeyaphvintplaflIKSALNTnifgepgwqGTGWR 703
Cdd:TIGR02074 436 ------------TTQVISPATAYIMTDM-------------------------------LKGVVES---------GTGRS 463
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 704 AgrDLQRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTasgaikdqisgyegGAKSAQPAWDAYMKA 783
Cdd:TIGR02074 464 A--RLPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTLGKSGT--------------GGGLAAPIWRDFMAE 527
|
....
gi 585376740 784 VLEG 787
Cdd:TIGR02074 528 ALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
54-230 |
9.36e-91 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 283.64 E-value: 9.36e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 54 DGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSP 133
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 134 ERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLY 213
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 585376740 214 SMDRAVARRNVVLSRML 230
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-850 |
0e+00 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 1914.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 1 MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVK 80
Cdd:PRK11636 1 MKFVKYLLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 81 AFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL 160
Cdd:PRK11636 81 AFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQF 240
Cdd:PRK11636 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 241 DQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPA 320
Cdd:PRK11636 241 DQARSEPIVANYHAPEIAFSAPYLSEMVRQEMYNRYGENAYEDGYRVYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 321 NVLWKVGESAWDNNKITDTLKALPTYGPLLPAAVTSANPQEATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVTD 400
Cdd:PRK11636 321 NVLWKVGESAWDNKKITDTLKALPTYGPLLPAVVTSANPQEATAMLADGSSVALPMEGVRWARPYRSDTQQGPTPRKVTD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 401 VLQTGQQIWVRQVGDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL 480
Cdd:PRK11636 401 VVQTGQQIWVRQVDDAWWLAQVPDVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 481 TLASMLNDVPISRWDAGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGFPAQNIVHTES 560
Cdd:PRK11636 481 TLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTES 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 561 LALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDTQKSNVLENNDVEDVAI 640
Cdd:PRK11636 561 LALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKVACPECDIPVIYGDTQKSNVLENDDVENVAT 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 641 SREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTT 720
Cdd:PRK11636 641 SQEQQNSSVPMPQLEQANQALVAQNGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWMGTGWRAGRDLKRRDIGGKTGTT 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 721 NSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPGIV 800
Cdd:PRK11636 721 NSSKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTASGAIKDQISGYEGGAKSAQPAWDDYMKAALEGVPEQPLTPPPGIV 800
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 585376740 801 TVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF 850
Cdd:PRK11636 801 TVNIDRSTGKLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGETHELF 850
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
1-850 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 1217.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 1 MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVK 80
Cdd:COG5009 1 MRLLKILLILLLLLLLLGALAVAGLYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLIN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 81 AFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL 160
Cdd:COG5009 81 AFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQF 240
Cdd:COG5009 161 ELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 241 DQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGE-SAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGP 319
Cdd:COG5009 241 EAAKAEPLTARYHGASAEVDAPYFAEMVRRELVERYGEdALYTGGLKVYTTLDPRLQEAAEKALRDGLLAYDRRHGYRGP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 320 ANVLWkVGESAWDnnkitDTLKALPTYGPLLPAAVTSANPQEATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVT 399
Cdd:COG5009 321 EAHLD-LAEEDWD-----EALAEVPDVGDLRPAVVLEVDDKSARVGLRDGETGTLPLEGLKWARPYINDNRRGPAPKSAS 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 400 DVLQTGQQIWVRQVGDA-WWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDK 478
Cdd:COG5009 395 DVLKPGDVIRVRPVADGgWRLRQIPEVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFVYAAALDN 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 479 GLTLASMLNDVPISRWDAGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGFPAQnIVHT 558
Cdd:COG5009 475 GYTPATIINDAPIVFDDGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIYSK-LPPN 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 559 ESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDipviygdtqksnvlenndvedv 638
Cdd:COG5009 554 LSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARACEDCD---------------------- 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 639 aisreQQNVSVPMPQLeqanqalvaktgaQEYAPHVINTPLAFLIKSALNTNIfgepgWQGTGWRAgRDLqRRDIGGKTG 718
Cdd:COG5009 612 -----AAEWDGAEPRL-------------PDPAEQVIDPRTAYQMTSMLRGVV-----QRGTGRRA-RAL-GRDIAGKTG 666
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 719 TTNSSKDAWFSGYGPGVVTSVWIGFDDHrRNLGHttasgaikdqisgYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG 798
Cdd:COG5009 667 TTNDSKDAWFVGFTPDLVAGVWVGFDDP-RSLGR-------------GETGGRAALPIWIDFMKAALKDKPEKPFPVPEG 732
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 585376740 799 IVTVNIDRSTGQLANGG--NSREEYFIEGTQPTQQAVHEVGTTiIDNGEAQELF 850
Cdd:COG5009 733 IVTVRIDPKTGLLASPGdpDAIFEAFKPGTEPTESASEDLGPD-ASEGTGEGLF 785
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-832 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 632.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 1 MKFVKYFLILAVCCILLGAGSIYGLYRYIEpqLPDVATLKDVRLQIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVK 80
Cdd:COG0744 11 LRRLLGLLLLLLAVLVLAALAGLVALYVAD--LPDPEELEDLALPQTSTIYDRDGTLIATLGDENREWVPLDQIPPHLKD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 81 AFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL 160
Cdd:COG0744 89 AVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEIL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQF 240
Cdd:COG0744 169 ELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 241 DQTRTEAIN-ANYHAPEIAFSAPYLSEMVRQEMYNRYGESA-YEDGYRIYTTITRKVQQAAQQAVRNNVldydmrhgyrg 318
Cdd:COG0744 249 DAAKAEPLTlVPPPNGAAAGKYPYFVDYVRRELEELLGEDDlYRGGLKIYTTLDPKLQKAAEKAVKNVL----------- 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 319 panvlwkvgesawdnnkitdtlkalptygpllpaavtsanpqeatamladgstvalsmegvrwarpyrsdtqqgptPRKV 398
Cdd:COG0744 318 ----------------------------------------------------------------------------PEGK 321
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 399 TDVLQTgqqiwvrqvgdawwlaqvpevnsALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDK 478
Cdd:COG0744 322 PGGLQA-----------------------ALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEQ 378
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 479 GLTLASMLNDVPISrwdaGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGFPaQNIVHT 558
Cdd:COG0744 379 GYTPATTVDDEPVT----FPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT-SPLDPN 453
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 559 ESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKvacpecdipviygdtqksnvlenndvedv 638
Cdd:COG0744 454 PSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPK----------------------------- 504
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 639 aisREQqnvsvpmpqleqanqalvaktgaqeyaphVINTPLAFLIKSALNTNIFGepgwqGTGWRAGrdLQRRDIGGKTG 718
Cdd:COG0744 505 ---CEQ-----------------------------VISPEVAYLMTDMLQDVVTS-----GTGRAAR--LPGRPVAGKTG 545
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 719 TTNSSKDAWFSGYGPGVVTSVWIGFDDHRRNlghttasgaikdqisGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG 798
Cdd:COG0744 546 TTNDNRDAWFVGYTPQLVTAVWVGNDDNSPM---------------GYVTGGSLPAPIWRDFMEAALEGLPVEDFPKPSG 610
|
810 820 830
....*....|....*....|....*....|....
gi 585376740 799 IVTVNIDRSTGQlanggnsreeyfieGTQPTQQA 832
Cdd:COG0744 611 VVRIDEPSPTPS--------------GTEPTETS 630
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
65-787 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 561.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 65 RRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEV 144
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 145 FLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNV 224
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 225 VLSRMLDEGYITQQQFDQTRTEAINANYHAP-EIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAV 303
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKkSEQYKAPYFVDYVIQELEEEYGEELYTGGLKIYTTLDLDAQKAAEKVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 304 RNNVLDYDMRHGYrgpanvlwkvgesawdnnkitdtlkalptygpllpaavtsanpqeatamladgstvalsmegvrwar 383
Cdd:TIGR02074 241 NTGLRVAGRRDGD------------------------------------------------------------------- 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 384 pyrsdtqqgptprkvtdvlqtgqqiwvrqvgdawwlaqvpEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQV 463
Cdd:TIGR02074 254 ----------------------------------------DLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQP 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 464 GSNIKPFLYTAAMDKGLTLASMLNDVPISrwdAGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAE 543
Cdd:TIGR02074 294 GSTFKPFVYAAALEKGLTPATIVNDEPIT---YNGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVA 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 544 YLQRFGFPAqNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKvacpecdipviygd 623
Cdd:TIGR02074 371 LAKRFGITS-PLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPK-------------- 435
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 624 tqksnvlenndvEDVAISREQQNVSVPMpqleqanqalvaktgaqeyaphvintplaflIKSALNTnifgepgwqGTGWR 703
Cdd:TIGR02074 436 ------------TTQVISPATAYIMTDM-------------------------------LKGVVES---------GTGRS 463
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 704 AgrDLQRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTasgaikdqisgyegGAKSAQPAWDAYMKA 783
Cdd:TIGR02074 464 A--RLPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTLGKSGT--------------GGGLAAPIWRDFMAE 527
|
....
gi 585376740 784 VLEG 787
Cdd:TIGR02074 528 ALKN 531
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
36-830 |
4.70e-109 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 351.33 E-value: 4.70e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 36 VATLKDVRLQIPMQIYSADGELIA----QYGEKRRIpVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFS 111
Cdd:TIGR02071 114 LSKIENLDNNKEFGFFRLDPKLIAmlysPNGEQRLF-VPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTA 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 112 GHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRA----YGVGAAAQVYFGKT 187
Cdd:TIGR02071 193 GRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDARYSKDRILELYLNEVYLGQSGddaiHGFPLASQYYFGRP 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 188 VDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQFDQTRTEAINANyHAPEIAFSAPYLSEM 267
Cdd:TIGR02071 273 LGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQKIIDDEEYDMLSARPLGVQ-KKGGIISRQPAFLQL 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 268 VRQEMYNRYGESAYED-GYRIYTTITRKVQQAAQQAVRnnvldydmrhgyrgpanvlwkvgesawdnnkitDTLKALpty 346
Cdd:TIGR02071 352 VRRELRQKLGDKVKDLsGLRIFTTLDPVSQSAAEQAVQ---------------------------------ETIPAL--- 395
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 347 gpllpaavtsanpqeatamladgstvalsmEGVRwarpyrsdtqqgptprkvtdvlqtgqqiwvrqvgdawwlaQVPEVN 426
Cdd:TIGR02071 396 ------------------------------KKKK----------------------------------------KLPDLE 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 427 SALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMD--KGLTLASMLNDVPISRWDAGaGSDWQP 504
Cdd:TIGR02071 406 AAMVVTDRFTGEVRAMVGGSDPQFAGFNRALQARRQIGSLVKPAVYLTALSqpDKYRLNTWIEDQPLSIKLSN-GQVWSP 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 505 KNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGG 584
Cdd:TIGR02071 485 QNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGINKDEIPPVPSMLLGAINLTPYEVAQLYQTIASGG 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 585 FLVDPWFISKIENDQGGVIFEAKPKVAcpecdipviygdtqksnvlenndvedvaisreqqnvsvPMPQLEQANQALVA- 663
Cdd:TIGR02071 565 NRAPLSAVRSVLDEDGKVLYQSDPQAE--------------------------------------QAVPSQAAYLTLYAm 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 664 KTGAQEyaphvintplafliksalntnifgepgwqGTGWRAGRDLQRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGF 743
Cdd:TIGR02071 607 QQVVQR-----------------------------GTARSLGADFPSLSLAGKTGTTNDNRDSWFAGIDGKEVTIIWLGR 657
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 744 DDHRRNlGHTTASGAIkdQIsgyeggaksaqpaWDAYMKavlEGVPEQ-PLTPPPGIVTVNIDRSTGQL--ANGGNSREE 820
Cdd:TIGR02071 658 DDNGPT-KLTGASGAL--QV-------------YARYLS---YQTPEPlLLVPPEGIDWFGVDPQGNGGckANCPGARRL 718
|
810
....*....|
gi 585376740 821 YFIEGTQPTQ 830
Cdd:TIGR02071 719 PIWTGNPQAL 728
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
5-830 |
5.39e-101 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 331.03 E-value: 5.39e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 5 KYFLILAVCCILLGAGsIYGLYRYIEPQL---PDVATLkdvrlqipmqIYSADGELIAQY---GEKRRIPVTLDQIPPEM 78
Cdd:COG4953 9 RRLLALLLALLLLALA-LWALDRLFPLPLlfaVPYSTV----------VLDRDGTLLRAFlaaDGQWRLPVPLDEVSPRY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 79 VKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARnffLS--PERTLMRKIKEVFLAIRIEQLLTK 156
Cdd:COG4953 78 LQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQVAR---LLepRPRTLSGKLRQILRALQLERRYSK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 157 DEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYIT 236
Cdd:COG4953 155 DEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVID 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 237 QQQFDQTRTEAINANYHAPeiAFSAPYLSEMVRQEmynrygesaYEDGYRIYTTITRKVQQAAQQAVRNnvldydmrhgy 316
Cdd:COG4953 235 AEEAALALLEPVPARRRPL--PQLAPHLARRLLRQ---------LPGGTRIRTTLDAGLQRRLERLVRR----------- 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 317 rgpanvlwkvgesawdnnkitdtlkalptygpllpaavtsanpqeatamladgstvalsmegvrwarpyrsdtqqgptpr 396
Cdd:COG4953 --------------------------------------------------------------------------------
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 397 kvtdvlqtgqqiWVRQvgdawwLAQVPEVNSALVSINPQNGAVMALVGGFDFN---QSKFNRATQALRQVGSNIKPFLYT 473
Cdd:COG4953 293 ------------YVRR------LKQNGIHNAAVLVVDNRTGEVLAYVGSADFFdasRQGQVDMVRALRSPGSTLKPFLYG 354
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 474 AAMDKGLTL-ASMLNDVPISRwdagagSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGFPA 552
Cdd:COG4953 355 LALDQGLIHpETLLADVPTSF------GGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRL 428
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 553 QNIVHTE---SLALGSASFTPMQVARGYAVMANGGFLVDPWFiskiendqggvifeakpkvacpecdipviygdtqksnv 629
Cdd:COG4953 429 LLPPAEHyglSLILGGAEVTLEELVGLYAALARGGEARPLRL-------------------------------------- 470
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 630 lenndvedvaisREQQNVSVPMPQLEQANQALVAKTGAQEYAPhvintplafliksalntnifgepgWQGTGWRAGRDLQ 709
Cdd:COG4953 471 ------------LAGEPASPGRRLLSPGAAWLVRDILSDVPRP------------------------DGAFGWRALDSPP 514
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 710 RrdIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTtasgaikdqisgyegGAKSAQPAWDAYMKAVLEGVP 789
Cdd:COG4953 515 P--IAWKTGTSYGFRDAWAVGFTGRYTVGVWVGNPDGTPVPGLT---------------GAEAAAPLLFDIFDLLPASRW 577
|
810 820 830 840
....*....|....*....|....*....|....*....|...
gi 585376740 790 EQPLTPPPGIVTVNIDRSTGQLANG--GNSREEYFIEGTQPTQ 830
Cdd:COG4953 578 PLPFPPPAGLLRVEVCAPSGLLAGPncPQRVTEWFIPGTSPPT 620
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
54-230 |
9.36e-91 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 283.64 E-value: 9.36e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 54 DGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSP 133
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 134 ERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLY 213
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 585376740 214 SMDRAVARRNVVLSRML 230
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
50-843 |
3.61e-73 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 254.27 E-value: 3.61e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 50 IYSADGELIAQY---GEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLA 126
Cdd:TIGR02073 14 VLDRHGTLLRALlanDGQWRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRRVSGGSTLTMQLA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 127 RNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAP 206
Cdd:TIGR02073 94 RLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLAALPQAP 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 207 STFNPLYSMDRAVARRNVVLSRMLDEGYITQQQFDQTRTEAINA-NYHAPEIafsAPYLSEMVRQEmynrygesAYEDGY 285
Cdd:TIGR02073 174 SARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPLPAlPEPLPQL---APHFALKLLRA--------RPEIAS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 286 RIYTTITRKVQQAAQQAVRNNvldydmrhgyrgpanvlwkvgesawdnnkitdtLKALPtygpllpaavtsanpqeatam 365
Cdd:TIGR02073 243 VIVSTLDADLQRRLEELARRY---------------------------------LSALR--------------------- 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 366 ladgstvalsmegvrwarpyrsdtqqgptPRKVtdvlqtgqqiwvrqvgdawwlaqvpeVNSALVSINPQNGAVMALVGG 445
Cdd:TIGR02073 269 -----------------------------PRGI--------------------------SNLAILVVDNRSGAVLAYVGS 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 446 FDFNQ-SKFNR--ATQALRQVGSNIKPFLYTAAMDKGLTLA-SMLNDVPiSRWdagagSDWQPKNSPPQYAGPIRLRQGL 521
Cdd:TIGR02073 294 ADFFDdSNSGQvdGVRAPRSPGSTLKPFLYALALDDGLLHPdSLLKDVP-LRF-----GDYAPENFDKTFHGPVPAREAL 367
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 522 GQSKNVVMVRAMRAMGVDYSAEYLQRFGFP---AQNIVHTESLALGSASFTPMQVARGYAVMANGGflvdpwfiskiend 598
Cdd:TIGR02073 368 ARSLNIPAVRLLERVGPPRFADFLRQAGLNllkPKSDYYGLSLALGGAEITLQDLANLYAMLANQG-------------- 433
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 599 qggvifEAKPKVACPecdipviygdtqksnvlenndvedvaisrEQQNVSVPMPQLEQANQALVAKTGAQEYAPHVIntp 678
Cdd:TIGR02073 434 ------LSGPLRFLQ-----------------------------TDAKRPERERLLSPGAAWIVLDILKDRPRPDDT--- 475
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 679 lafLIKSALntnifgePGWQGTGWragrdlqrrdiggKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTtasga 758
Cdd:TIGR02073 476 ---LPLSAL-------PTRLPLAW-------------KTGTSYGFRDAWAAGVSGRYTIGVWVGNFDGKPNPGFF----- 527
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 759 ikdqisgyegGAKSAQPAWdaymKAVLEGVPE-QPLTPPPGIVTVNIDRSTGQLANGG--NSREEYFIEGTQPTQQAVHE 835
Cdd:TIGR02073 528 ----------GAAAAAPLL----FDILDALQAsEASTLPRPLKEVPGCLVLGNLPILPcpEQISTWFLPGGSPPTLSEPH 593
|
....*...
gi 585376740 836 VGTTIIDN 843
Cdd:TIGR02073 594 KPVVILIN 601
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
41-818 |
2.10e-69 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 245.83 E-value: 2.10e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 41 DVRLqIPMqIYSADGEliaqygekRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGAST 120
Cdd:PRK09506 196 DPRL-ITM-LQSPNGE--------QRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGST 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 121 ITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGY----RAYGVGAAAQVYFGKTVDQLTLNEM 196
Cdd:PRK09506 266 LTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRILELYLNEVYLGQsgddQIRGFPLASLYYFGRPVEELSLDQQ 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 197 AVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQFD---------QTRTEAInanyhAPEIAFsapylSEM 267
Cdd:PRK09506 346 ALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDmlsarplgvQPKGGVI-----SPQPAF-----MQM 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 268 VRQEMYNRYGESAYE-DGYRIYTTITRKVQQAAQQAVRNNVldydmrhgyrgpanvlwkvgesawdnnkitdtlkalpty 346
Cdd:PRK09506 416 VRQELQAKLGDKVKDlSGVKIFTTLDPVSQDAAEKAVEEGI--------------------------------------- 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 347 gPLLPAAvtsanpqeatamladgstvalsmegvrwarpyrsdtqqgptpRKVTDvlqtgqqiwvrqvgdawwlaqvpeVN 426
Cdd:PRK09506 457 -PALKKQ------------------------------------------RKLSD------------------------LE 469
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 427 SALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGLT--LASMLNDVPISRWDAGaGSDWQP 504
Cdd:PRK09506 470 TAMVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPDKyrLNTWIADAPISLRQPN-GQVWSP 548
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 505 KNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGG 584
Cdd:PRK09506 549 QNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGG 628
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 585 FLVDPWFISKIENDQGGVIFEAKPkvacpecdipviygdtqksnvlenndvedvaisreQQNVSVPmpqleqANQALVAK 664
Cdd:PRK09506 629 NRAPLSALRSVIAEDGKVLYQSFP-----------------------------------QAERAVP------AQAAYLTL 667
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 665 TGAQEYAPHvintplafliksalntnifgepgwqGTGWRAGRDLQRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFD 744
Cdd:PRK09506 668 YTMQQVVQR-------------------------GTGRQLGAKYPNLHLAGKTGTTNDLVDSWFAGIDGKEVTITWVGRD 722
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 585376740 745 DHRR-NLghTTASGAIkdqisgyeggaksaqpawdAYMKAVLEGVPEQPL--TPPPGIVTVNIDRSTGQLANGGNSR 818
Cdd:PRK09506 723 NNQPtKL--YGASGAM-------------------TIYQRYLENQTPTPLnlTPPEDIVDMGVDYDGNFVCGSGGMR 778
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
23-823 |
3.49e-67 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 238.59 E-value: 3.49e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 23 YGLYRyIEPQLpdvatlkdvrlqIPMQiYSADGEliaqygekRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIF 102
Cdd:PRK14850 136 FSFLR-LDPKL------------IAML-YSPEGK--------KRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIG 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 103 RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGY----RAYGVGA 178
Cdd:PRK14850 194 RAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILDRFYSKDRILELYLNEVYLGQdgneQIRGFPL 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 179 AAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHApEIA 258
Cdd:PRK14850 274 ASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTLKRRNLVLFLLYKQKVITRKLYKDLCSRPLNVQSKG-NII 352
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 259 FSAPYLSEMVRQEMYNRYGESAYE-DGYRIYTTITRKVQQAAQQAvrnnvldydMRHGYRgpanvlwkvgesawdnnkit 337
Cdd:PRK14850 353 SSHPAFIQLVCEEFHKKIHYPFKNfSGTKIFTTLDYISQNAAEQA---------VKIGIP-------------------- 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 338 dtlkalptygpllpaavtsanpqeatamladgstvalsmegvRWARPYRsdtqqgptprkvtdvlqtgqqiwvrqvgdaw 417
Cdd:PRK14850 404 ------------------------------------------ILKRKKR------------------------------- 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 418 wlaqVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDK--GLTLASMLNDVPISrWD 495
Cdd:PRK14850 411 ----LKDLEVAMVIIDRFSGEVRALIGSSKPEFNGYNRALKARRSIGSLSKPITYLTALSQpeKYHLNTWISDTPIS-IK 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 496 AGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGFPAQNIVHTESLALGSASFTPMQVAR 575
Cdd:PRK14850 486 LDNGQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSNYITPLPSISLGAINLTPMEVAQ 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 576 GYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVAcpecdipviygdtqksnvlenndvedvaisreqqnvsvpmpqle 655
Cdd:PRK14850 566 VFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSK-------------------------------------------- 601
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 656 qanqalvaktgaqeyapHVINTPLAFLIKSALNTNIFgepgwQGTGWRAGRDLQRRDIGGKTGTTNSSKDAWFSGYGPGV 735
Cdd:PRK14850 602 -----------------HVESSQASYLTLYAMQQVVK-----SGTAKSLGTIFKEFSLAGKTGTTNNLVDSWFVGIDGKQ 659
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 736 VTSVWIGFDDHrrnlgHTT----ASGAIKdqisgyeggaksaqpAWDAYMKavLEGVPEQPLTPPPGIVTVNIDRSTGQL 811
Cdd:PRK14850 660 VVITWIGRDNN-----HTTklygSSGAMK---------------IYKRYLQ--YQNPVPLVLKAPNNINMFYINNLGELF 717
|
810
....*....|..
gi 585376740 812 ANGGNSREEYFI 823
Cdd:PRK14850 718 CKKGNNQYNRML 729
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
66-584 |
5.90e-46 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 176.81 E-value: 5.90e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 66 RIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARnfFLSPE-RTLMRKIKEV 144
Cdd:PRK11240 62 RYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVAR--LLDPHpRTFGGKIRQL 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 145 FLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNV 224
Cdd:PRK11240 140 WRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNK 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 225 VLSRMLDEGYITQQQFDQTRTEAInanyhapeiaFSAPylsemvRQEmynrygesayedgyriyttitrkvqqaaqqavr 304
Cdd:PRK11240 220 VLERMAEQGVWSAEQVKESREEPV----------WLAP------RQM--------------------------------- 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 305 nnvldydmrhgyrgpanvlwkvgesawdnnkitdtlkalPTYGPLLPAAVTSANPQEatamladgstvalsmegvrwarp 384
Cdd:PRK11240 251 ---------------------------------------PQLAPLFARMMLGKSKSD----------------------- 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 385 yrsdtqqgptprKVTDVLQTGQQiwvRQVGD--AWWLAQVPEVNS-ALVSINPQNGAVMALVGGFDFN-QSKFNRA--TQ 458
Cdd:PRK11240 269 ------------KIVTTLDAGLQ---RRLEDlaLNWKGRLPPRSSlAMIVVDHTDMAVRGWVGSVDLNdDSRFGHVdmVN 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 459 ALRQVGSNIKPFLYTAAMDKGLT-LASMLNDVPiSRWDagagsDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMG 537
Cdd:PRK11240 334 AIRSPGSVLKPFVYGLALDDGLIhPASLLQDVP-RRTG-----DYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYG 407
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 585376740 538 VDYSAEYLQRFGFPAQNIVHTE---SLALGSASFTPMQVARGYAVMANGG 584
Cdd:PRK11240 408 PKRFAAKLRNVGLPLYLPAGAEpnlSLILGGAGARLEDMVAAYSAFARHG 457
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
63-246 |
3.45e-42 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 153.81 E-value: 3.45e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 63 EKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALfSGHASQGASTITQQLARNFFLSPERTLMRKIK 142
Cdd:PRK13481 42 ENKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTI-SDRDVQGGSTITQQVVKNYFYDNERSFTRKVK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 143 EVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVD-------QLTLNEMAVIAGLPKAPSTFNPLYSM 215
Cdd:PRK13481 121 ELFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNknsttmsHITVLQSAILASKVNAPSVYNINDMS 200
|
170 180 190
....*....|....*....|....*....|.
gi 585376740 216 DRAVARRNVVLSRMLDEGYITQQQFDQTRTE 246
Cdd:PRK13481 201 ENFTQRVSTNLEKMKQQNYINETQYQQAMSQ 231
|
|
| PCB_OB |
pfam17092 |
Penicillin-binding protein OB-like domain; |
316-425 |
2.19e-40 |
|
Penicillin-binding protein OB-like domain;
Pssm-ID: 465343 [Multi-domain] Cd Length: 111 Bit Score: 143.93 E-value: 2.19e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 316 YRGPANVLWKVGESAWDNNKITDTLKALPTYGPLLPAAVTSANPQEATAMLADGSTVALSMEGVRWARPYRSDTQQGPTP 395
Cdd:pfam17092 1 YRGPEAHLDLPADWAERLAAIDEALADLPDVGGLRPAVVLSVSPKSARVGLRDGETGTIPGEGLRWARPYLSDKRQGPAP 80
|
90 100 110
....*....|....*....|....*....|.
gi 585376740 396 RKVTDVLQTGQQIWVRQVGD-AWWLAQVPEV 425
Cdd:pfam17092 81 KSASDVLKPGDVIRVRPNGDgGWRLRQVPEV 111
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
69-213 |
1.79e-35 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 134.13 E-value: 1.79e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 69 VTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAI 148
Cdd:TIGR02070 58 RPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATW 137
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585376740 149 RIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAG-LPkapstfNPLY 213
Cdd:TIGR02070 138 MLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAvLP------NPKY 197
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
428-610 |
4.42e-21 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 98.36 E-value: 4.42e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 428 ALVSINPQNGAVMALVGGFDFNQSKF---------NRATQALRQVGSNIKPFLYTAAMDKGL-TLASMLND--------V 489
Cdd:COG0768 250 AVVVMDPKTGEILAMASYPSFDPNLFvggpdeplrNRAVQGTYEPGSTFKPFTAAAALEEGViTPDTTFDCpgyyrvggR 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 490 PISRWDAGAgsdwqpknsppqyAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGF--------P--AQNIVHTE 559
Cdd:COG0768 330 TIRDWDRGG-------------HGTLTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLgqktgidlPgeASGLLPSP 396
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 585376740 560 S----LALGSASF------TPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKV 610
Cdd:COG0768 397 KrwypGETATMSIgqglsvTPLQLAQAYAAIANGGVLVKPHLVKEIVDPDGEVVKEEPEVL 457
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
428-599 |
7.57e-21 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 94.02 E-value: 7.57e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 428 ALVSINPQNGAVMALVGGFDFNQSKF-----NRATQALRQVGSNIKPFLYTAAMDKG-LTLASMLNDVPISRWDAGAGSD 501
Cdd:pfam00905 2 SAVVLDPKTGEVLAMVGKPSYDPNGFigplrNRAVTSRYEPGSTFKPFTALAALDNGvLKPDETIFDWPGKQQGGKSIGD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 502 WQPKNsppqyAGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGF--------PAQN--IVHTESLALGSASF--- 568
Cdd:pfam00905 82 WNQDQ-----VGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYgnktgiglPGENagYLTPYWLEGATASFgig 156
|
170 180 190
....*....|....*....|....*....|....
gi 585376740 569 ---TPMQVARGYAVMANGGFLVDPWFISKIENDQ 599
Cdd:pfam00905 157 ltiTPLQQAQAYAAIANGGKLVPPHLVKSIEDKV 190
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
428-733 |
8.02e-16 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 81.42 E-value: 8.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 428 ALVSINPQNGAVMALVG--GFDFNQ------SK-------------FNRATQALRQVGSNIKPFLYTAAMDKGLTLASMl 486
Cdd:TIGR03423 250 AVVVMDPRTGEILAMVStpSFDPNLfvdgisSKdykallndpdrplLNRAIQGVYPPGSTFKPVVALAALEEGVITPET- 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 487 ndvpiSRWDAGAGS-------DWQPKNSppqyaGPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGF--------P 551
Cdd:TIGR03423 329 -----RIYCPGYFQlggrrfrCWKRGGH-----GRVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKRFGFgqktgidlP 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 552 AQN--IVHTE-----------------SLALGSA--SFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKV 610
Cdd:TIGR03423 399 GEKsgLVPSRewkrkrfgqpwypgdtlNVSIGQGyvLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRTEPEV 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 611 acpecdipviygdtqksnvlenndVEDVAISREqqnvsvpmpQLEQANQALVAktgaqeyaphVINTPlafliksalntn 690
Cdd:TIGR03423 479 ------------------------LRPLPISPE---------NLDVVREGMRD----------VVNGP------------ 503
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 585376740 691 ifgepgwQGTGWRAGRDLQRRdIGGKTGT-------TNSSKD-----------AWFSGYGP 733
Cdd:TIGR03423 504 -------GGTARRARLGLPYK-MAGKTGTaqvvslkQGEKYDaeqiperlrdhALFVAFAP 556
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
427-550 |
3.32e-03 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 40.91 E-value: 3.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585376740 427 SALVSINPQNGAVMALVGGFDFNQSKF---------------------NRATQALRQVGSNIKPFLYTAAMDKG-LTLAS 484
Cdd:PRK10795 272 AAVVVTDPRTGGILALVSTPSYDPNLFvdgisskdysgllndpnrpliNRATQGVYPPASTVKPYVAVSALSAGvITRNT 351
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 585376740 485 MLNDvpiSRWdagagsdWQPKNSPPQYA-------GPIRLRQGLGQSKNVVMVRAMRAMGVDYSAEYLQRFGF 550
Cdd:PRK10795 352 SLFD---PGW-------WQLPGSEKRYRdwkkwghGRLNVTKSLEESADTFFYQVAYDMGIDRLSEWMGKFGY 414
|
|
| |
