|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
35-455 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 720.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 115 KNEKKGLkDWEKRLIISDRAHLgdsgqqeAVDGLQEvqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEFS 194
Cdd:pfam00709 81 ELEERGI-DVPDRLFISDRAHLilp-yhkALDGLRE---EARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVFR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 195 SRFKNLAHQHQSMFPTL---EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYPFV 271
Cdd:pfam00709 155 EKLEALLELKNKLLEKLygePLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEG-KKILFEGAQGTLLDIDHGTYPYV 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 272 TSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYA 351
Cdd:pfam00709 234 TSSNTTAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 352 HMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYI 431
Cdd:pfam00709 314 VRINGVTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYV 393
|
410 420
....*....|....*....|....
gi 578825468 432 RFVENHVGVAVKWVGVGKSRESMI 455
Cdd:pfam00709 394 EFIEELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
33-455 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 651.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEE 112
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 113 AEKNEKKGLkDWEKRLIISDRAHLGDSGQQEaVDglqevqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDE 192
Cdd:smart00788 81 IEELEAKGV-DVKDRLFISDRAHLILPYHIA-LD-------KAREKARIGTTGRGIGPAYEDKVARRGIRVGDLF-DEEV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 193 FSSRFKNLAHQHQSMFPTL----EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTY 268
Cdd:smart00788 151 LREKLEELLDYKNFLLKKLygaePVDVEEILEELLEYAERLRPYVTDVSELLNEALKAG-KKVLFEGAQGTLLDIDHGTY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 269 PFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMIL 348
Cdd:smart00788 230 PYVTSSNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLL 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 349 RYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQ 428
Cdd:smart00788 310 RYAVRINGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAK 389
|
410 420
....*....|....*....|....*..
gi 578825468 429 NYIRFVENHVGVAVKWVGVGKSRESMI 455
Cdd:smart00788 390 KYIERIEELVGVPVSIISTGPDREQTI 416
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
30-455 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 614.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 30 GSRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGL 109
Cdd:PTZ00350 11 KSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 110 FEEAEKNEKKGlKDWEKRLIISDRAHLGDSGQQeAVDGLQEvQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsD 189
Cdd:PTZ00350 91 LEEIEQLTKKG-INLLGRLYISDRAHLVFDLHQ-AIDGIQE-SEKGKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLL-N 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 190 FDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGTYP 269
Cdd:PTZ00350 167 FETFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIK-EGKRVLVEGANATMLDIDFGTYP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 270 FVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILR 349
Cdd:PTZ00350 246 YVTSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALR 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 350 YAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGK--RIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQA 427
Cdd:PTZ00350 326 YVQMINGFDSINLTKLDVLSGLKEIKICVNYKNKGTglEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENA 405
|
410 420
....*....|....*....|....*...
gi 578825468 428 QNYIRFVENHVGVAVKWVGVGKSRESMI 455
Cdd:PTZ00350 406 QKYVLFIEELLGVPIVWIGVGPNRENMI 433
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
33-457 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 607.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEE 112
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 113 AEKNEKKGLkDWEKRLIISDRAHLGDSGQQeAVDGLQEvqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDE 192
Cdd:COG0104 81 IDGLEARGV-DVRSRLRISERAHLILPYHR-ALDKARE---EARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPEV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 193 FSSRFKNLAHQHQSMFPTL----EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALH-GppKKILVEGANAALLDIDFGT 267
Cdd:COG0104 155 LREKLEELLEYKNFLLEKLygaePLDFEELLEEYLEYAERLKPYVADTSELLNEALKaG--KKVLFEGAQGTLLDIDHGT 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 268 YPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMI 347
Cdd:COG0104 233 YPYVTSSNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 348 LRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQA 427
Cdd:COG0104 313 LRYAVRINGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENA 392
|
410 420 430
....*....|....*....|....*....|
gi 578825468 428 QNYIRFVENHVGVAVKWVGVGKSRESMIQL 457
Cdd:COG0104 393 RAYVERIEELLGVPISIVSVGPDREQTIVR 422
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
32-455 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 508.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 32 RVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFE 111
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 112 EAEKNEKKGLkDWEKRLIISDRAHLGDSGQQEaVDGLQEVQRQaqeGKNIGTTKKGIGPTYSSKAARTGLRICDllsdfd 191
Cdd:cd03108 81 EIEELEKKGI-DVKGRLLISDRAHLVFPYHQE-LDGLEEKERG---GKKIGTTKRGIGPAYADKAARTGIRVGD------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 192 efssrfknlahqhqsmfptleidiegqlkrlkgfaerirPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGTYPFV 271
Cdd:cd03108 150 ---------------------------------------PYVVDTVELLNEALK-AGKKVLFEGAQGTLLDIDFGTYPYV 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 272 TSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYA 351
Cdd:cd03108 190 TSSNTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYA 269
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 352 HMVNGFTALALTKLDIldvlgevkvgvsyklngkripyfpanqemlqkveveyetlpgwkadttgarrwedlppQAQNYI 431
Cdd:cd03108 270 VRINGLTELALTKLDV----------------------------------------------------------NAQKYI 291
|
410 420
....*....|....*....|....
gi 578825468 432 RFVENHVGVAVKWVGVGKSRESMI 455
Cdd:cd03108 292 ERIEELLGVPITYISVGPDREQTI 315
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
35-457 |
5.15e-174 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 494.76 E-value: 5.15e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 115 KNEKkGLKDWEKRLIISDRAHLGDSGQQEavdgLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD---FD 191
Cdd:TIGR00184 81 YLEK-RGISVRDRLFVSYRCHLILPYHKK----LDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDeafAE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 192 EFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYPFV 271
Cdd:TIGR00184 156 KAKNILEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEG-EKVLFEGAQGTMLDIDYGTYPYV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 272 TSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYA 351
Cdd:TIGR00184 235 TSSNTTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 352 HMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYI 431
Cdd:TIGR00184 315 CRLNGATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYI 394
|
410 420
....*....|....*....|....*.
gi 578825468 432 RFVENHVGVAVKWVGVGKSRESMIQL 457
Cdd:TIGR00184 395 ERIEELTGVPVTIISTGPEREQTIDL 420
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
33-356 |
1.09e-26 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 109.00 E-value: 1.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQ-GGNNAGHTVVVD-GKEYDFHLLPSGI-INTKAVSFIGNGVVIHLPGL 109
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTYIDDeGRKFVHRMLPNGIvSPPLKQVLIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 110 FEEAEKNEKKGLkDWEKRLIISDRAHLgdsgqqeaVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTglricdllsd 189
Cdd:NF038379 81 REEIEELEDAGH-DVGKRLLIHEQATV--------IELHKHVEEEAGPMTKIGSTKKGIGAARAAKIRRN---------- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 190 fdefssrfknlahqhqsmfPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYP 269
Cdd:NF038379 142 -------------------PSTLGDAEGDFGEGAVRDQPWEIAERVVDNALYDFALQAAERIQIEGTQGYSLGLHAGFYP 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 270 FVTSSNCTVGGVCTGLGIPPQNI--GDVYGVVKAYTTRVGIGAFPT---------EQIneigGLLQtrghEWGVTTGRKR 338
Cdd:NF038379 203 YCTSRDCTPADFLADAGIPLPNVdaFKVVGTARTYPIRVAGWSGNSypdqgettwEEL----GLPE----ELTTVTKKVR 274
|
330
....*....|....*...
gi 578825468 339 RCGWLDLMILRYAHMVNG 356
Cdd:NF038379 275 RVGTFSAEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
35-455 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 720.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 115 KNEKKGLkDWEKRLIISDRAHLgdsgqqeAVDGLQEvqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEFS 194
Cdd:pfam00709 81 ELEERGI-DVPDRLFISDRAHLilp-yhkALDGLRE---EARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVFR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 195 SRFKNLAHQHQSMFPTL---EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYPFV 271
Cdd:pfam00709 155 EKLEALLELKNKLLEKLygePLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEG-KKILFEGAQGTLLDIDHGTYPYV 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 272 TSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYA 351
Cdd:pfam00709 234 TSSNTTAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 352 HMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYI 431
Cdd:pfam00709 314 VRINGVTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYV 393
|
410 420
....*....|....*....|....
gi 578825468 432 RFVENHVGVAVKWVGVGKSRESMI 455
Cdd:pfam00709 394 EFIEELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
33-455 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 651.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEE 112
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 113 AEKNEKKGLkDWEKRLIISDRAHLGDSGQQEaVDglqevqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDE 192
Cdd:smart00788 81 IEELEAKGV-DVKDRLFISDRAHLILPYHIA-LD-------KAREKARIGTTGRGIGPAYEDKVARRGIRVGDLF-DEEV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 193 FSSRFKNLAHQHQSMFPTL----EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTY 268
Cdd:smart00788 151 LREKLEELLDYKNFLLKKLygaePVDVEEILEELLEYAERLRPYVTDVSELLNEALKAG-KKVLFEGAQGTLLDIDHGTY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 269 PFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMIL 348
Cdd:smart00788 230 PYVTSSNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLL 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 349 RYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQ 428
Cdd:smart00788 310 RYAVRINGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAK 389
|
410 420
....*....|....*....|....*..
gi 578825468 429 NYIRFVENHVGVAVKWVGVGKSRESMI 455
Cdd:smart00788 390 KYIERIEELVGVPVSIISTGPDREQTI 416
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
30-455 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 614.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 30 GSRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGL 109
Cdd:PTZ00350 11 KSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 110 FEEAEKNEKKGlKDWEKRLIISDRAHLGDSGQQeAVDGLQEvQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsD 189
Cdd:PTZ00350 91 LEEIEQLTKKG-INLLGRLYISDRAHLVFDLHQ-AIDGIQE-SEKGKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLL-N 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 190 FDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGTYP 269
Cdd:PTZ00350 167 FETFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIK-EGKRVLVEGANATMLDIDFGTYP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 270 FVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILR 349
Cdd:PTZ00350 246 YVTSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALR 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 350 YAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGK--RIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQA 427
Cdd:PTZ00350 326 YVQMINGFDSINLTKLDVLSGLKEIKICVNYKNKGTglEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENA 405
|
410 420
....*....|....*....|....*...
gi 578825468 428 QNYIRFVENHVGVAVKWVGVGKSRESMI 455
Cdd:PTZ00350 406 QKYVLFIEELLGVPIVWIGVGPNRENMI 433
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
33-457 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 607.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEE 112
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 113 AEKNEKKGLkDWEKRLIISDRAHLGDSGQQeAVDGLQEvqrQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDE 192
Cdd:COG0104 81 IDGLEARGV-DVRSRLRISERAHLILPYHR-ALDKARE---EARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPEV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 193 FSSRFKNLAHQHQSMFPTL----EIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALH-GppKKILVEGANAALLDIDFGT 267
Cdd:COG0104 155 LREKLEELLEYKNFLLEKLygaePLDFEELLEEYLEYAERLKPYVADTSELLNEALKaG--KKVLFEGAQGTLLDIDHGT 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 268 YPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMI 347
Cdd:COG0104 233 YPYVTSSNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 348 LRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQA 427
Cdd:COG0104 313 LRYAVRINGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENA 392
|
410 420 430
....*....|....*....|....*....|
gi 578825468 428 QNYIRFVENHVGVAVKWVGVGKSRESMIQL 457
Cdd:COG0104 393 RAYVERIEELLGVPISIVSVGPDREQTIVR 422
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
32-457 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 592.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 32 RVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFE 111
Cdd:PRK01117 2 KNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 112 EAEKNEKKGLkDWEKRLIISDRAHLgdsgqqeAVDGLQEVQRqaqeGKN-IGTTKKGIGPTYSSKAARTGLRICDLLsDF 190
Cdd:PRK01117 82 EIDELEARGV-DVRERLRISERAHLilp-yhrALDKAREKAR----GKKkIGTTGRGIGPAYEDKVARRGIRVGDLL-DP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 191 DEFSSRFKNLAHQH----QSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALH-GppKKILVEGANAALLDIDF 265
Cdd:PRK01117 155 ETFAEKLEENLEYKnfllTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKaG--KRVLFEGAQGTLLDIDH 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 266 GTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDL 345
Cdd:PRK01117 233 GTYPFVTSSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 346 MILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPP 425
Cdd:PRK01117 313 VALRYAVRVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPE 392
|
410 420 430
....*....|....*....|....*....|..
gi 578825468 426 QAQNYIRFVENHVGVAVKWVGVGKSRESMIQL 457
Cdd:PRK01117 393 NARKYIKRIEELTGVPISIISTGPDRDQTIIL 424
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
31-455 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 575.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 31 SRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVV-VDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGL 109
Cdd:PLN02513 2 SQVSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYnDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 110 FEEAEKNEKKGLkDWEKRLIISDRAHLGDSGQQEaVDGLQEVQRqaqEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsD 189
Cdd:PLN02513 82 FEEIDGLESNGV-SCEGRLLVSDRAHLLFDFHQE-VDGLREAEL---AGSKIGTTKRGIGPAYSSKATRNGLRVGDLR-H 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 190 FDEFSSRFKNLAHQHQSMFPTLEID---IEGQLKRLKGFAERIRPMVRDGVYFMYEAlHGPPKKILVEGANAALLDIDFG 266
Cdd:PLN02513 156 MDTFAEKLRELLADAAARFEGFEYDasmVEEEVEAYKKFAERLEPFITDTVHYLNEA-IQAGKKILVEGAQATMLDIDFG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 267 TYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLM 346
Cdd:PLN02513 235 TYPFVTSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 347 ILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKL-NGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPP 425
Cdd:PLN02513 315 ALKYSCQINGFTSLNLTKLDVLSGLPEIKIGVAYKTpDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPA 394
|
410 420 430
....*....|....*....|....*....|
gi 578825468 426 QAQNYIRFVENHVGVAVKWVGVGKSRESMI 455
Cdd:PLN02513 395 AAQAYVERIEELVGVPVHYIGVGPGRDALI 424
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
32-455 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 508.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 32 RVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFE 111
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 112 EAEKNEKKGLkDWEKRLIISDRAHLGDSGQQEaVDGLQEVQRQaqeGKNIGTTKKGIGPTYSSKAARTGLRICDllsdfd 191
Cdd:cd03108 81 EIEELEKKGI-DVKGRLLISDRAHLVFPYHQE-LDGLEEKERG---GKKIGTTKRGIGPAYADKAARTGIRVGD------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 192 efssrfknlahqhqsmfptleidiegqlkrlkgfaerirPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGTYPFV 271
Cdd:cd03108 150 ---------------------------------------PYVVDTVELLNEALK-AGKKVLFEGAQGTLLDIDFGTYPYV 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 272 TSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYA 351
Cdd:cd03108 190 TSSNTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYA 269
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 352 HMVNGFTALALTKLDIldvlgevkvgvsyklngkripyfpanqemlqkveveyetlpgwkadttgarrwedlppQAQNYI 431
Cdd:cd03108 270 VRINGLTELALTKLDV----------------------------------------------------------NAQKYI 291
|
410 420
....*....|....*....|....
gi 578825468 432 RFVENHVGVAVKWVGVGKSRESMI 455
Cdd:cd03108 292 ERIEELLGVPITYISVGPDREQTI 315
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
35-457 |
5.15e-174 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 494.76 E-value: 5.15e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 115 KNEKkGLKDWEKRLIISDRAHLGDSGQQEavdgLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD---FD 191
Cdd:TIGR00184 81 YLEK-RGISVRDRLFVSYRCHLILPYHKK----LDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDeafAE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 192 EFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDFGTYPFV 271
Cdd:TIGR00184 156 KAKNILEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEG-EKVLFEGAQGTMLDIDYGTYPYV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 272 TSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYA 351
Cdd:TIGR00184 235 TSSNTTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 352 HMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYI 431
Cdd:TIGR00184 315 CRLNGATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYI 394
|
410 420
....*....|....*....|....*.
gi 578825468 432 RFVENHVGVAVKWVGVGKSRESMIQL 457
Cdd:TIGR00184 395 ERIEELTGVPVTIISTGPEREQTIDL 420
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
34-457 |
1.00e-121 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 361.58 E-value: 1.00e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 34 TVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEA 113
Cdd:PRK13787 4 SLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFIEEC 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 114 EKNEKKGLKDWEKrLIISDRAHLGDSGQQEaVDGLQEVQrQAQEGKnIGTTKKGIGPTYSSKAARTGLRICDLLSDfdEF 193
Cdd:PRK13787 84 DRLQKEGFPVKDK-LLLSDACHLLFPYHSQ-IDSARETT-SSQEHK-IGTTKKGIGICYADKMMRTGLRVGDLLDK--SY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 194 SSRFKNLAH-------QHQSMFPTLEIDIEgqlKRLKGFAERIRPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFG 266
Cdd:PRK13787 158 KRRLKHLVDeknreldKLYGMPPVSYNDIN---DGLKFFLSKVGKNIINTAYYLDTELK-KGKRVLLEGAQGTGLDVDFG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 267 TYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLM 346
Cdd:PRK13787 234 TYPYVTSSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVE 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 347 ILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPAnqEMLQKVEVEYETLPGWKADTTGARRWEDLPPQ 426
Cdd:PRK13787 314 MLKHSVRINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPS--QGLEKVEPLYEEFPGWKDDISGINEFQKLPEK 391
|
410 420 430
....*....|....*....|....*....|.
gi 578825468 427 AQNYIRFVENHVGVAVKWVGVGKSRESMIQL 457
Cdd:PRK13787 392 CKNYISALEKWIGVKINLVSTGPDRKDTIIG 422
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
34-456 |
1.91e-115 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 345.25 E-value: 1.91e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 34 TVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVsFIGNGVVIHLPGLFEEA 113
Cdd:PRK13786 3 TIITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARV-LIGPGVVLNPEVLAEEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 114 EKNEKKGLKDWEKRLIISDRAHLGDSGQQEaVDGLQEVQRQAQegknIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEF 193
Cdd:PRK13786 82 DMLEKHGVKVDAEKLGIDAKTSIIMPYHIE-LDGLRESARTEK----IGTTKRGIGFAYIDKIARDEVRMSDLV-DKERL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 194 SSRFKNLAHQHQSMFPTLEIDI-----EGQLKRLKGFAERIRPMVRDGVYFMYEALHgPPKKILVEGANAALLDIDFGTY 268
Cdd:PRK13786 156 MRRLEELAPQKEKEIKELGGDPsivrdEALIDKYLELGRQLAPYITDVSYEINKALD-EGKSVLAEGAQGTHLDVIHGTQ 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 269 PFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMIL 348
Cdd:PRK13786 235 KFVTSSSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLL 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 349 RYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQ 428
Cdd:PRK13786 315 KKAIYLNGYTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENAR 394
|
410 420
....*....|....*....|....*...
gi 578825468 429 NYIRFVENHVGVAVKWVGVGKSRESMIQ 456
Cdd:PRK13786 395 NYVERLEELMGVPIKYISVGPGREQTFK 422
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
35-457 |
2.94e-114 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 341.70 E-value: 2.94e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:PRK13783 4 VIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVEELE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 115 KNEKKGlKDWEKRLIISDRAHLGDSGQQEaVDGLQEVQRqaqeGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDfDEFS 194
Cdd:PRK13783 84 ELKEKF-PDYSGRIFISELAHVVLPVHKE-LDEIIESVR----KNAIGTTKRGIGPAYADKVMRVGVRLADLFDE-EKLR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 195 SRFKNLAHQHQSMFpTLEIDIEGQLKRLKGFAERIRPMVRDGVYfMYEALHGppKKILVEGANAALLDIDFGTYPFVTSS 274
Cdd:PRK13783 157 EFLEKILSLYKKLY-GIEFDVEKMMEDLLTFYEKIKDLVVSPVE-IKRILEE--KSVLFEGTQGVLLDLDVGTYPYVTSS 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 275 NCTVGGVCTGLGIPPQnIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMV 354
Cdd:PRK13783 233 NCSTTGVSAGMGFPVK-VDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 355 NGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYfPANQEMLQKVEVEYETLPGWKadTTGARRWEDlppqaqnYIRFV 434
Cdd:PRK13783 312 SGVDSLVMTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGWK--SLEDKNFLK-------FVDFI 381
|
410 420
....*....|....*....|...
gi 578825468 435 ENHVGVAVKWVGVGKSRESMIQL 457
Cdd:PRK13783 382 ERETGRKIAYISTGPKIEEIVEV 404
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
36-452 |
1.86e-111 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 334.47 E-value: 1.86e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 36 VLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEK 115
Cdd:PRK13788 6 IIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFAEEREN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 116 NEKKGLkdwEKRLIISDRAHLGDSgQQEAVDGlqevqrqaqeGKN-IGTTKKGIGPTYSSKAARTGLRICDLLSD--FDE 192
Cdd:PRK13788 86 LRAGGL---NPKLLISERAHLVLP-HHKYVDG----------RKNfVGTTGRGIGPAYSDRARRVGIRFGDLLDEavLRE 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 193 FSSRFknLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEAL-HGppKKILVEGANAALLDIDFGTYPFV 271
Cdd:PRK13788 152 RVERL--LEAKPNSTREAGWDTVEKALADLAPMREILLPFIADTGSLLREAIrEG--KRVLFEGAQATLLDLNYGTYPYV 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 272 TSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRG----HEWGVTTGRKRRCGWLDLMI 347
Cdd:PRK13788 228 TSSHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 348 LRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKripyfpanqemlqkveVEYETLPGWkADTTGARRWEDLPPQA 427
Cdd:PRK13788 308 LKYACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDGQ----------------PVYKELPGW-GDLDGVKSREALPKEA 370
|
410 420
....*....|....*....|....*
gi 578825468 428 QNYIRFVENHVGVAVKWVGVGKSRE 452
Cdd:PRK13788 371 QAYLELIEETTGVPVVMFSTSPRRE 395
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
33-457 |
1.23e-101 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 310.92 E-value: 1.23e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 33 VTVVlGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKaVSFIGNGVVIHLPGLFEE 112
Cdd:PRK13785 3 VTIV-GSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGK-IGVLGNGCVVNPETLFDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 113 AEKNEKKGLkDWEKRliISDRAHLgDSGQQEAVDGLQEvQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDE 192
Cdd:PRK13785 81 IDALRERGL-DPDVR--VAERAHV-ILPYHRVLDGIEE-EAKSDSDLEVGTTGRGIGPTYEDKAGRRGVRVGDLL-DPDV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 193 FSSRFKNLAHQHQSMFPTL----------EIDIEGQLKRLKGFAERIRP--MVRDGVYFMYEALHGPpKKILVEGANAAL 260
Cdd:PRK13785 155 LRDRLEYVVPQKRALAEDVygldasetpeAFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDG-DNVMLEGAQGTS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 261 LDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGD--VYGVVKAYTTRVGIGAFPTE---------------QINEIGGLL 323
Cdd:PRK13785 234 IDIDHGNYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTElggvegdtpdeggrpDEEELATYI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 324 QTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVE 403
Cdd:PRK13785 314 REEGGEYGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPN 393
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 578825468 404 YETLPGWKA---DTTGARRWEDLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMIQL 457
Cdd:PRK13785 394 FRSFDGWPEvdwAAVAEEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVL 450
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
35-455 |
2.88e-90 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 280.75 E-value: 2.88e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 35 VVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAE 114
Cdd:PRK13784 5 VIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALDEEIT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 115 KNEKKGLKDWEKRLIISDRAHLGDSGQQeavdgLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLsDFDEFS 194
Cdd:PRK13784 85 RLQAKGIAISAENLFVSESCTIITSYHK-----LLDAVRESNTSEKIGTTGKGIGPAYEDKVSRKGIKFKHLF-DKDLLR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 195 SRFKNLAHQHQSMF--------PTLEIDIEgqlkRLKGFAERIRPMVRDGVYFMYEALhGPPKKILVEGANAALLDIDFG 266
Cdd:PRK13784 159 SRLAISLAEKETLFrdlykveyPTLEQEFD----KLFALGQKLKQYAADTFSIIDQAI-AAGKNVVYEGAQGVLLDVDYG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 267 TYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLM 346
Cdd:PRK13784 234 TYPFVTSSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLP 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 347 ILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYKLNGKRIpYFPANQEMLQKVEVEYETLPGWKADTTGARrwEDLPPQ 426
Cdd:PRK13784 314 LLKYSAKCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEI-YCAYPGIDLYKVEPILVEMEPFSIDETVTK--DNMPAA 390
|
410 420
....*....|....*....|....*....
gi 578825468 427 AQNYIRFVENHVGVAVKWVGVGKSRESMI 455
Cdd:PRK13784 391 LKTYLKTIENHVGIPISSLAYGPSREQIL 419
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
33-457 |
1.22e-61 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 203.57 E-value: 1.22e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 33 VTVVLGAQWGDEGKGKVVDLLA-TD-ADIISRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLF 110
Cdd:PRK04293 3 CTIVVGGFFGDEGKGKIIAYLAlKDkPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEVLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 111 EEAEKNEKKGlkdwekRLIISDRAHLgdsgqqeavdgLQEVQRQAQEG-----KNIGTTKKGIGPTYSSKAARTGlricD 185
Cdd:PRK04293 83 KEVEELNVGG------RVFVDYRCGI-----------IEEKHVEEDRSdehlsKKIGSTGTGCGPANADRVLRRL----K 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 186 LLSDFDEfssrfknlahqhqsmfptleidiegqlkrlkgfaerIRPMVRDGVYFMYEALHGPpKKILVEGANAALLDIDF 265
Cdd:PRK04293 142 LAKDVEE------------------------------------LEKYLTDVPEEVNEALDRG-ENVLIEGTQGFGLSLYY 184
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 266 GTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGgllQTRG-HEWGVTTGRKRRCGWLD 344
Cdd:PRK04293 185 GTYPYVTSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEA---EKLGlVEYGTVTGRRRRVGPFD 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 345 LMILRYAHMVNGFTALALTKLDILDvlgevkvgvsyklngkripyfpanqemlqkveveyetlpgwkADTTGARRWEDLP 424
Cdd:PRK04293 262 FELARRAARINGATQIAITKLDKLD------------------------------------------KEAYGVTEYDKLP 299
|
410 420 430
....*....|....*....|....*....|...
gi 578825468 425 PQAQNYIRFVENHVGVAVKWVGVGKSRESMIQL 457
Cdd:PRK04293 300 PEAKKFIEEIEEELGVPVTLISTGPELEDTIDL 332
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
33-356 |
1.09e-26 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 109.00 E-value: 1.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 33 VTVVLGAQWGDEGKGKVVDLLATDADIISRCQ-GGNNAGHTVVVD-GKEYDFHLLPSGI-INTKAVSFIGNGVVIHLPGL 109
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTYIDDeGRKFVHRMLPNGIvSPPLKQVLIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 110 FEEAEKNEKKGLkDWEKRLIISDRAHLgdsgqqeaVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTglricdllsd 189
Cdd:NF038379 81 REEIEELEDAGH-DVGKRLLIHEQATV--------IELHKHVEEEAGPMTKIGSTKKGIGAARAAKIRRN---------- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 190 fdefssrfknlahqhqsmfPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKILVEGANAALLDIDFGTYP 269
Cdd:NF038379 142 -------------------PSTLGDAEGDFGEGAVRDQPWEIAERVVDNALYDFALQAAERIQIEGTQGYSLGLHAGFYP 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 270 FVTSSNCTVGGVCTGLGIPPQNI--GDVYGVVKAYTTRVGIGAFPT---------EQIneigGLLQtrghEWGVTTGRKR 338
Cdd:NF038379 203 YCTSRDCTPADFLADAGIPLPNVdaFKVVGTARTYPIRVAGWSGNSypdqgettwEEL----GLPE----ELTTVTKKVR 274
|
330
....*....|....*...
gi 578825468 339 RCGWLDLMILRYAHMVNG 356
Cdd:NF038379 275 RVGTFSAEQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
33-198 |
2.46e-10 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 62.76 E-value: 2.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 33 VTVVLGAQWGDEGKGKVVDLLATD--ADIISRCQGGNNAGHTVVVD-GKEYDFHLLPSGIINTKAVSFIGNGVVIHlPGL 109
Cdd:PTZ00351 171 VIMVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMD-PVS 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578825468 110 FEEAEKNE--KKGLkDWEKRLIISDRAHLgdSGQQEAVDGLQEVQRQaqegknigTTKKGIGPTYSSKAARTGLRICDLL 187
Cdd:PTZ00351 250 FMEKEIIQliDAGI-DYRDRLFIGNVCIV--TPYHKLLDLLGSAANS--------STLKGMAPVHGSKVMKRGIRLDHIF 318
|
170
....*....|.
gi 578825468 188 SDFDEFSSRFK 198
Cdd:PTZ00351 319 NDDETLRKRLE 329
|
|
| |
