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Conserved domains on  [gi|578807238|ref|XP_006713634|]
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target of Nesh-SH3 isoform X37 [Homo sapiens]

Protein Classification

fibronectin type III domain-containing protein( domain architecture ID 10414115)

fibronectin type III (FN3) domain-containing protein may be involved in specific interactions with other molecules through its FN3 domain

Gene Ontology:  GO:0005515
PubMed:  8981327

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
706-1203 3.82e-16

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 85.38  E-value: 3.82e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  706 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 761
Cdd:PHA03247 2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  762 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 838
Cdd:PHA03247 2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  839 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 913
Cdd:PHA03247 2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  914 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 992
Cdd:PHA03247 2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  993 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1070
Cdd:PHA03247 2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1071 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1150
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 578807238 1151 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1203
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
PHA03247 super family cl33720
large tegument protein UL36; Provisional
377-908 1.20e-10

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.89  E-value: 1.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  377 PQFELPLSTLAPKSLPEFP--EAKTPFPFEKPRG--TLASSEK----PWIVPTAK-ISEDSKVLQPQTAP-------QQT 440
Cdd:PHA03247 2506 PDAPPAPSRLAPAILPDEPvgEPVHPRMLTWIRGleELASDDAgdppPPLPPAAPpAAPDRSVPPPRPAPrpsepavTSR 2585
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  441 TSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTTPAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLP 518
Cdd:PHA03247 2586 ARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPSPSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSR 2663
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  519 SQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVPKSKPalePATIQPEPLVPTTASKPSERPKTTHRPD 598
Cdd:PHA03247 2664 PRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAP---HALVSATPLPPGPAAARQASPALPAAPA 2740
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  599 APQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETEAPSMTIVPTTDIEP-----------VTVRTEATVT 663
Cdd:PHA03247 2741 PPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTRPAVASLSESRESLPspwdpadppaaVLAPAAALPP 2820
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  664 TLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAPTTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPA 738
Cdd:PHA03247 2821 AASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GDVRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTE 2896
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  739 TILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE-------LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPV 811
Cdd:PHA03247 2897 SFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqppLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVP 2975
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  812 TFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPVPATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKT 886
Cdd:PHA03247 2976 RFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPPPVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLE 3053
                         570       580
                  ....*....|....*....|..
gi 578807238  887 TPRPEAPESKPVPTAELKPVTL 908
Cdd:PHA03247 3054 ALDPLPPEPHDPFAHEPDPATP 3075
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
1485-1576 1.00e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 57.12  E-value: 1.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1485 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1562
Cdd:cd00063     2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
                          90
                  ....*....|....
gi 578807238 1563 LGEGPVSNTVAFST 1576
Cdd:cd00063    80 GGESPPSESVTVTT 93
PRK10263 super family cl35903
DNA translocase FtsK; Provisional
1086-1338 8.52e-06

DNA translocase FtsK; Provisional


The actual alignment was detected with superfamily member PRK10263:

Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 50.85  E-value: 8.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1086 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1163
Cdd:PRK10263  327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1164 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1243
Cdd:PRK10263  402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1244 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1312
Cdd:PRK10263  474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550
                         250       260       270
                  ....*....|....*....|....*....|..
gi 578807238 1313 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1338
Cdd:PRK10263  551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
FN3 super family cl27307
Fibronectin type 3 domain [General function prediction only];
1302-1581 4.55e-04

Fibronectin type 3 domain [General function prediction only];


The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.99  E-value: 4.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1302 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1381
Cdd:COG3401    48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1382 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1458
Cdd:COG3401   128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1459 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1537
Cdd:COG3401   208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 578807238 1538 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1581
Cdd:COG3401   283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
FN3 super family cl21522
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
123-202 5.48e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


The actual alignment was detected with superfamily member pfam00041:

Pssm-ID: 473895 [Multi-domain]  Cd Length: 85  Bit Score: 40.48  E-value: 5.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   123 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 199
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71

                   ...
gi 578807238   200 GVK 202
Cdd:pfam00041   72 RVQ 74
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
706-1203 3.82e-16

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 85.38  E-value: 3.82e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  706 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 761
Cdd:PHA03247 2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  762 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 838
Cdd:PHA03247 2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  839 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 913
Cdd:PHA03247 2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  914 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 992
Cdd:PHA03247 2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  993 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1070
Cdd:PHA03247 2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1071 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1150
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 578807238 1151 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1203
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
PHA03247 PHA03247
large tegument protein UL36; Provisional
377-908 1.20e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.89  E-value: 1.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  377 PQFELPLSTLAPKSLPEFP--EAKTPFPFEKPRG--TLASSEK----PWIVPTAK-ISEDSKVLQPQTAP-------QQT 440
Cdd:PHA03247 2506 PDAPPAPSRLAPAILPDEPvgEPVHPRMLTWIRGleELASDDAgdppPPLPPAAPpAAPDRSVPPPRPAPrpsepavTSR 2585
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  441 TSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTTPAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLP 518
Cdd:PHA03247 2586 ARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPSPSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSR 2663
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  519 SQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVPKSKPalePATIQPEPLVPTTASKPSERPKTTHRPD 598
Cdd:PHA03247 2664 PRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAP---HALVSATPLPPGPAAARQASPALPAAPA 2740
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  599 APQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETEAPSMTIVPTTDIEP-----------VTVRTEATVT 663
Cdd:PHA03247 2741 PPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTRPAVASLSESRESLPspwdpadppaaVLAPAAALPP 2820
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  664 TLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAPTTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPA 738
Cdd:PHA03247 2821 AASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GDVRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTE 2896
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  739 TILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE-------LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPV 811
Cdd:PHA03247 2897 SFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqppLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVP 2975
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  812 TFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPVPATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKT 886
Cdd:PHA03247 2976 RFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPPPVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLE 3053
                         570       580
                  ....*....|....*....|..
gi 578807238  887 TPRPEAPESKPVPTAELKPVTL 908
Cdd:PHA03247 3054 ALDPLPPEPHDPFAHEPDPATP 3075
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
1485-1576 1.00e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 57.12  E-value: 1.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1485 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1562
Cdd:cd00063     2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
                          90
                  ....*....|....
gi 578807238 1563 LGEGPVSNTVAFST 1576
Cdd:cd00063    80 GGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
1486-1566 1.45e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 50.69  E-value: 1.45e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   1486 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 1563
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80

                    ...
gi 578807238   1564 GEG 1566
Cdd:smart00060   81 GEG 83
PRK10263 PRK10263
DNA translocase FtsK; Provisional
1086-1338 8.52e-06

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 50.85  E-value: 8.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1086 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1163
Cdd:PRK10263  327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1164 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1243
Cdd:PRK10263  402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1244 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1312
Cdd:PRK10263  474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550
                         250       260       270
                  ....*....|....*....|....*....|..
gi 578807238 1313 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1338
Cdd:PRK10263  551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
fn3 pfam00041
Fibronectin type III domain;
1486-1569 4.18e-05

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 43.56  E-value: 4.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  1486 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 1562
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78

                   ....*..
gi 578807238  1563 LGEGPVS 1569
Cdd:pfam00041   79 GGEGPPS 85
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1302-1581 4.55e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.99  E-value: 4.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1302 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1381
Cdd:COG3401    48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1382 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1458
Cdd:COG3401   128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1459 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1537
Cdd:COG3401   208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 578807238 1538 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1581
Cdd:COG3401   283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
fn3 pfam00041
Fibronectin type III domain;
123-202 5.48e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.48  E-value: 5.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   123 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 199
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71

                   ...
gi 578807238   200 GVK 202
Cdd:pfam00041   72 RVQ 74
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
571-937 5.68e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 44.76  E-value: 5.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   571 PATIQPEPLVPTTASKPSERPKtthrPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTD 650
Cdd:pfam03154  179 GAASPPSPPPPGTTQAATAGPT----PSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQ 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   651 IEPVTVRT-----EATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDFGPITPGTS-SAPTTTTKRTRRPHPKPKT 724
Cdd:pfam03154  255 PPPPSQVSpqplpQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSpAAPGQSQQRIHTPPSQSQL 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   725 TPHPEVPQTKLVPATILEPVLRTEAsgTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIFEPVSPIK-EAPGTTFV 803
Cdd:pfam03154  335 QSQQPPREQPLPPAPLSMPHIKPPP--TTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLStHHPPSAHP 412
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   804 PVTDLEPVTFRTEIPATT--LATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTlRPEASTTLASKTSQRTRRPR 881
Cdd:pfam03154  413 PPLQLMPQSQQLPPPPAQppVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGG-PPPITPPSGPPTSTSSAMPG 491
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   882 LRTKTTPRPEAPESKP-VPTAELKPVTLRTETWVTTQAPKT---SQRTRRPRPKTKTTPS 937
Cdd:pfam03154  492 IQPPSSASVSSSGPVPaAVSCPLPPVQIKEEALDEAEEPESpppPPRSPSPEPTVVNTPS 551
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1480-1624 5.72e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.61  E-value: 5.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1480 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 1557
Cdd:COG3401   324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578807238 1558 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1624
Cdd:COG3401   398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
124-202 5.74e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 40.29  E-value: 5.74e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238    124 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 199
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72

                    ...
gi 578807238    200 GVK 202
Cdd:smart00060   73 RVR 75
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
123-202 2.75e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 2.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  123 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 200
Cdd:cd00063     3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73

                  ..
gi 578807238  201 VK 202
Cdd:cd00063    74 VR 75
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
706-1203 3.82e-16

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 85.38  E-value: 3.82e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  706 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 761
Cdd:PHA03247 2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  762 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 838
Cdd:PHA03247 2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  839 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 913
Cdd:PHA03247 2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  914 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 992
Cdd:PHA03247 2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  993 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1070
Cdd:PHA03247 2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1071 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1150
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 578807238 1151 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1203
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
PHA03247 PHA03247
large tegument protein UL36; Provisional
563-953 2.72e-14

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 79.21  E-value: 2.72e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  563 PKSKPALEPATiqPEPLVPTT--ASKPSERPKTT--HRPDAPQIQ--------PGSKPPKQLLPKPQTTAEPDMPPTKSV 630
Cdd:PHA03247 2553 PPLPPAAPPAA--PDRSVPPPrpAPRPSEPAVTSraRRPDAPPQSarprapvdDRGDPRGPAPPSPLPPDTHAPDPPPPS 2630
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  631 SEPVPFETEAPSMTIVPttdiEPVTVRTEATVTTLA-PKTSQRTRTRRPRPKHKTTPRPETLQTkldfgPITPGTSSA-- 707
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVP----PPERPRDDPAPGRVSrPRRARRLGRAAQASSPPQRPRRRAARP-----TVGSLTSLAdp 2701
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  708 PTTTTKRTRRPHPKPKTTPHPEVPQT--KLVPATILEPVLRTEASGTT--------AAPKVPQRTHRPHPK--PKTTLSP 775
Cdd:PHA03247 2702 PPPPPTPEPAPHALVSATPLPPGPAAarQASPALPAAPAPPAVPAGPAtpggparpARPPTTAGPPAPAPPaaPAAGPPR 2781
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  776 EELQTELVPATIFEPVSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATv 855
Cdd:PHA03247 2782 RLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG- 2860
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  856 lePVTLRPEASTTlASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTlrtetwvTTQAPKTSQRTRRPRPKTKTT 935
Cdd:PHA03247 2861 --DVRRRPPSRSP-AAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPP-------QPQAPPPPQPQPQPPPPPQPQ 2930
                         410       420
                  ....*....|....*....|.
gi 578807238  936 PSPEV---PQTKLVPSTDLEP 953
Cdd:PHA03247 2931 PPPPPpprPQPPLAPTTDPAG 2951
PHA03247 PHA03247
large tegument protein UL36; Provisional
377-908 1.20e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.89  E-value: 1.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  377 PQFELPLSTLAPKSLPEFP--EAKTPFPFEKPRG--TLASSEK----PWIVPTAK-ISEDSKVLQPQTAP-------QQT 440
Cdd:PHA03247 2506 PDAPPAPSRLAPAILPDEPvgEPVHPRMLTWIRGleELASDDAgdppPPLPPAAPpAAPDRSVPPPRPAPrpsepavTSR 2585
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  441 TSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTTPAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLP 518
Cdd:PHA03247 2586 ARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPSPSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSR 2663
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  519 SQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVPKSKPalePATIQPEPLVPTTASKPSERPKTTHRPD 598
Cdd:PHA03247 2664 PRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAP---HALVSATPLPPGPAAARQASPALPAAPA 2740
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  599 APQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETEAPSMTIVPTTDIEP-----------VTVRTEATVT 663
Cdd:PHA03247 2741 PPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTRPAVASLSESRESLPspwdpadppaaVLAPAAALPP 2820
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  664 TLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAPTTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPA 738
Cdd:PHA03247 2821 AASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GDVRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTE 2896
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  739 TILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE-------LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPV 811
Cdd:PHA03247 2897 SFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqppLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVP 2975
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  812 TFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPVPATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKT 886
Cdd:PHA03247 2976 RFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPPPVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLE 3053
                         570       580
                  ....*....|....*....|..
gi 578807238  887 TPRPEAPESKPVPTAELKPVTL 908
Cdd:PHA03247 3054 ALDPLPPEPHDPFAHEPDPATP 3075
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
1485-1576 1.00e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 57.12  E-value: 1.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1485 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1562
Cdd:cd00063     2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
                          90
                  ....*....|....
gi 578807238 1563 LGEGPVSNTVAFST 1576
Cdd:cd00063    80 GGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
1486-1566 1.45e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 50.69  E-value: 1.45e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   1486 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 1563
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80

                    ...
gi 578807238   1564 GEG 1566
Cdd:smart00060   81 GEG 83
PRK10263 PRK10263
DNA translocase FtsK; Provisional
629-1228 2.21e-06

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 52.78  E-value: 2.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  629 SVSEPVPFETEAPSMTIVPTTDIEPVTvrTEATVTTLAPKTSQRTRtrrprpKHKTTPRPETLQTKLDFGPitpgTSSAP 708
Cdd:PRK10263  315 PITEPVAVAAAATTATQSWAAPVEPVT--QTPPVASVDVPPAQPTV------AWQPVPGPQTGEPVIAPAP----EGYPQ 382
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  709 TTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIF 788
Cdd:PRK10263  383 QSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTY 462
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  789 EPVSPIKE--APGTTFVPVTDLEPVTFRTEIPATTlATKTSKRTRPPRPRPKTTPSPQ----APETKPVPATVLEPVTLR 862
Cdd:PRK10263  463 QTEQTYQQpaAQEPLYQQPQPVEQQPVVEPEPVVE-ETKPARPPLYYFEEVEEKRAREreqlAAWYQPIPEPVKEPEPIK 541
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  863 PEASTTLASKTSqrtrrprlrtkttPRPEAPESKPVpTAELKPVTLRTETWVTTQAPKTSQRTR-RPRPKTKTTPSPEVP 941
Cdd:PRK10263  542 SSLKAPSVAAVP-------------PVEAAAAVSPL-ASGVKKATLATGAAATVAAPVFSLANSgGPRPQVKEGIGPQLP 607
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  942 QtklvpstdlepgtlrteaPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----------SPEVPQNKS 1011
Cdd:PRK10263  608 R------------------PKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQynddeidamqQDELARQFA 669
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1012 VSVTGFEPVVHSTDAPGTT--------------FALTELQTLILKPVTSP---SLEMTESQPVSDVLEsvtlstESPKEt 1074
Cdd:PRK10263  670 QTQQQRYGEQYQHDVPVNAedadaaaeaelarqFAQTQQQRYSGEQPAGAnpfSLDDFEFSPMKALLD------DGPHE- 742
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1075 iaPAKTDYVYPTAKaPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQsitlPSPDEPQTEPAPKQTPRAPPKPkTSPR 1154
Cdd:PRK10263  743 --PLFTPIVEPVQQ-PQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQ----PQYQQPQQPVAPQPQYQQPQQP-VAPQ 814
                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578807238 1155 PRIPQTQPvPKVPQRVTAKPKTSPSpevsyttPAPKDVLLpHKPYPEVSQSEPVLQPVT-----FRFEPPKTTIAPLET 1228
Cdd:PRK10263  815 PQYQQPQQ-PVAPQPQYQQPQQPVA-------PQPQDTLL-HPLLMRNGDSRPLHKPTTplpslDLLTPPPSEVEPVDT 884
PRK10263 PRK10263
DNA translocase FtsK; Provisional
1086-1338 8.52e-06

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 50.85  E-value: 8.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1086 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1163
Cdd:PRK10263  327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1164 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1243
Cdd:PRK10263  402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1244 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1312
Cdd:PRK10263  474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550
                         250       260       270
                  ....*....|....*....|....*....|..
gi 578807238 1313 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1338
Cdd:PRK10263  551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
1043-1312 1.82e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 49.69  E-value: 1.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1043 PVTSPSLEMTESQPVSDVLESvtlstESPKETIAPAKTDYVYPTAKaplwPEEPKTEVVESITYVSEPPEttletspLPS 1122
Cdd:PTZ00449  520 PPKAPGDKEGEEGEHEDSKES-----DEPKEGGKPGETKEGEVGKK----PGPAKEHKPSKIPTLSKKPE-------FPK 583
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1123 QSitlPSPDEPQtEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA--KPKTSPSPEVSYTTPAPKDVLLPHKPYP 1200
Cdd:PTZ00449  584 DP---KHPKDPE-EPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESpkSPKRPPPPQRPSSPERPEGPKIIKSPKP 659
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1201 EVSQSEPvlqpvtfrFEPPKTTiapletrgiPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPhr 1280
Cdd:PTZ00449  660 PKSPKPP--------FDPKFKE---------KFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRP-- 720
                         250       260       270
                  ....*....|....*....|....*....|..
gi 578807238 1281 fYTTVRPRTSDKPHIRPvlnrttTRPTRPKPS 1312
Cdd:PTZ00449  721 -LPPKLPRDEEFPFEPI------GDPDAEQPD 745
PHA03247 PHA03247
large tegument protein UL36; Provisional
1089-1507 1.96e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.94  E-value: 1.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1089 APLWPEEPKTEVVESityvsEPPETTLETSPLPSQSitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVP---K 1165
Cdd:PHA03247 2591 APPQSARPRAPVDDR-----GDPRGPAPPSPLPPDT---HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPgrvS 2662
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1166 VPQRVTAK--PKTSPSPEVSYTTPAPKDVLLP---------------HKPYPEVSQSEPVLQPVTFRFEPPKTTIAPLeT 1228
Cdd:PHA03247 2663 RPRRARRLgrAAQASSPPQRPRRRAARPTVGSltsladpppppptpePAPHALVSATPLPPGPAAARQASPALPAAPA-P 2741
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1229 RGIPFIPMISPSPSQEELQTTLEETDQST--QEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPVLNRTTTRP 1306
Cdd:PHA03247 2742 PAVPAGPATPGGPARPARPPTTAGPPAPAppAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1307 TRPKPSGMPSGNGVGTGVKQAPRPSGADRNV--SVDSTHPTKKPGTRRPplppRPTHPRRKPLPPNNVTGKPGSAGIISS 1384
Cdd:PHA03247 2822 ASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggSVAPGGDVRRRPPSRS----PAAKPAAPARPPVRRLARPAVSRSTES 2897
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1385 GPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRfkgPHVRYIQKPDNSPCSITD 1464
Cdd:PHA03247 2898 FALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPS---GAVPQPWLGALVPGRVAV 2974
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 578807238 1465 SVKRFPkEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWE 1507
Cdd:PHA03247 2975 PRFRVP-QPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEE 3016
fn3 pfam00041
Fibronectin type III domain;
1486-1569 4.18e-05

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 43.56  E-value: 4.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  1486 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 1562
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78

                   ....*..
gi 578807238  1563 LGEGPVS 1569
Cdd:pfam00041   79 GGEGPPS 85
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
920-1316 5.99e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 48.15  E-value: 5.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  920 KTSQRTRRPRPKTKTTPSPEVPQTKLVPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPK 999
Cdd:PTZ00449  528 EGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPT 607
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1000 TTSSPEVPQNKSVSVTGFEPvvHSTDAPgttfaltelqtlilKPVTSPSLEMTESQPVSDVLESVTLSTESPKETIAPAK 1079
Cdd:PTZ00449  608 RPKSPKLPELLDIPKSPKRP--ESPKSP--------------KRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1080 TDYVYPT-AKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSP----- 1153
Cdd:PTZ00449  672 KEKFYDDyLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDiefft 751
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1154 -----RPRIPQTQPVPKVPQRVTAKPKTspsPEVSYTTPAPKDVL----LPHKPYPEVSQSEPVLQPVTFRFEPPKTTIA 1224
Cdd:PTZ00449  752 ppeeeRTFFHETPADTPLPDILAEEFKE---EDIHAETGEPDEAMkrpdSPSEHEDKPPGDHPSLPKKRHRLDGLALSTT 828
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1225 PLETRgiPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELA-----------KTTQAPHRFYTTVRPRTSDKP 1293
Cdd:PTZ00449  829 DLESD--AGRIAKDASGKIVKLKRSKSFDDLTTVEEAEEMGAEARKIVvdddgteaddeDTHPPEEKHKSEVRRRRPPKK 906
                         410       420
                  ....*....|....*....|...
gi 578807238 1294 HIRPVLNRTTTRPTRPKPSGMPS 1316
Cdd:PTZ00449  907 PSKPKKPSKPKKPKKPDSAFIPS 929
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
1112-1206 7.31e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 47.50  E-value: 7.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1112 ETTLETSPLPSQ-SITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPK 1190
Cdd:PRK14950  357 EALLVPVPAPQPaKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAI 436
                          90
                  ....*....|....*.
gi 578807238 1191 DVLLPHKPYPEVSQSE 1206
Cdd:PRK14950  437 PVDEKPKYTPPAPPKE 452
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1302-1581 4.55e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.99  E-value: 4.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1302 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1381
Cdd:COG3401    48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1382 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1458
Cdd:COG3401   128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1459 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1537
Cdd:COG3401   208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 578807238 1538 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1581
Cdd:COG3401   283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
461-777 4.56e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 45.07  E-value: 4.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  461 ERTTSAGTITPKISKSPEPTWTT-----PAPGKTQfislKP-KIPlspevTHTKPAPEPQTllpSQSTIGPETPgTKPST 534
Cdd:PTZ00449  533 EHEDSKESDEPKEGGKPGETKEGevgkkPGPAKEH----KPsKIP-----TLSKKPEFPKD---PKHPKDPEEP-KKPKR 599
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  535 TLAPRKTKRpgrrprpRPRPKTTPSPEVPKSKPALEPATIQPEPLVPTtaskpseRPKTTHRPDAPQIQPGSKPPKQllP 614
Cdd:PTZ00449  600 PRSAQRPTR-------PKSPKLPELLDIPKSPKRPESPKSPKRPPPPQ-------RPSSPERPEGPKIIKSPKPPKS--P 663
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  615 KPqttaepdmpptksvsepvPFEteaPSMTIVPTTDIEPVTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPrpetLQTK 694
Cdd:PTZ00449  664 KP------------------PFD---PKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP----FTTP 718
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  695 LDFGPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLS 774
Cdd:PTZ00449  719 RPLPPKLPRDEEFPFEPIGDPDAEQPDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEEDIHAETGEPDEAMKRPDS 798

                  ...
gi 578807238  775 PEE 777
Cdd:PTZ00449  799 PSE 801
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
1066-1400 4.58e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.16  E-value: 4.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1066 LSTESPKETIAPAKTDYVYPTAKAPLWPE-EPKTEVV--ESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQT 1142
Cdd:PHA03307   44 VSDSAELAAVTVVAGAAACDRFEPPTGPPpGPGTEAPanESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPP 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1143 PRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTFRFEPPKTT 1222
Cdd:PHA03307  124 ASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAAS 203
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1223 IAPLETRGIPFIPMISPSPS---QEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVR------PRTSDKP 1293
Cdd:PHA03307  204 PRPPRRSSPISASASSPAPApgrSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWeasgwnGPSSRPG 283
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1294 HIRPvlnRTTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT 1373
Cdd:PHA03307  284 PASS---SSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPA 360
                         330       340
                  ....*....|....*....|....*..
gi 578807238 1374 GKPGSAGIISSGPITTPPLRSTPRPTG 1400
Cdd:PHA03307  361 DPSSPRKRPRPSRAPSSPAASAGRPTR 387
PRK10263 PRK10263
DNA translocase FtsK; Provisional
1013-1266 5.00e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.08  E-value: 5.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1013 SVTgfEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESPkeTIAPAKTDYV-YPTAKAPL 1091
Cdd:PRK10263  315 PIT--EPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEP--VIAPAPEGYPqQSQYAQPA 390
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1092 WP-----EEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPK-----PKTSPRPRIPQTQ 1161
Cdd:PRK10263  391 VQyneplQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQqstfaPQSTYQTEQTYQQ 470
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1162 PVPK-----VPQRVTAKPKTSPSPEVSYTTPAPKDVL----LPHKPYPEVSQSEPVLQPVTFRFEPPKTTIAPLETRGIP 1232
Cdd:PRK10263  471 PAAQeplyqQPQPVEQQPVVEPEPVVEETKPARPPLYyfeeVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVA 550
                         250       260       270
                  ....*....|....*....|....*....|....
gi 578807238 1233 FIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 1266
Cdd:PRK10263  551 AVPPVEAAAAVSPLASGVKKATLATGAAATVAAP 584
fn3 pfam00041
Fibronectin type III domain;
123-202 5.48e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.48  E-value: 5.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   123 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 199
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71

                   ...
gi 578807238   200 GVK 202
Cdd:pfam00041   72 RVQ 74
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
571-937 5.68e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 44.76  E-value: 5.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   571 PATIQPEPLVPTTASKPSERPKtthrPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTD 650
Cdd:pfam03154  179 GAASPPSPPPPGTTQAATAGPT----PSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQ 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   651 IEPVTVRT-----EATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDFGPITPGTS-SAPTTTTKRTRRPHPKPKT 724
Cdd:pfam03154  255 PPPPSQVSpqplpQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSpAAPGQSQQRIHTPPSQSQL 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   725 TPHPEVPQTKLVPATILEPVLRTEAsgTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIFEPVSPIK-EAPGTTFV 803
Cdd:pfam03154  335 QSQQPPREQPLPPAPLSMPHIKPPP--TTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLStHHPPSAHP 412
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   804 PVTDLEPVTFRTEIPATT--LATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTlRPEASTTLASKTSQRTRRPR 881
Cdd:pfam03154  413 PPLQLMPQSQQLPPPPAQppVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGG-PPPITPPSGPPTSTSSAMPG 491
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   882 LRTKTTPRPEAPESKP-VPTAELKPVTLRTETWVTTQAPKT---SQRTRRPRPKTKTTPS 937
Cdd:pfam03154  492 IQPPSSASVSSSGPVPaAVSCPLPPVQIKEEALDEAEEPESpppPPRSPSPEPTVVNTPS 551
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1480-1624 5.72e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.61  E-value: 5.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1480 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 1557
Cdd:COG3401   324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578807238 1558 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1624
Cdd:COG3401   398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
124-202 5.74e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 40.29  E-value: 5.74e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238    124 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 199
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72

                    ...
gi 578807238    200 GVK 202
Cdd:smart00060   73 RVR 75
PRK11633 PRK11633
cell division protein DedD; Provisional
1087-1190 7.98e-04

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 43.07  E-value: 7.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1087 AKAPLWP---EEPKTEVVESITYV--SEPPETTLE-----TSPLPSQSITLPSPDEPQTEPAPKqtPRAPPKPKtsPRPR 1156
Cdd:PRK11633   39 AAIPLVPkpgDRDEPDMMPAATQAlpTQPPEGAAEavragDAAAPSLDPATVAPPNTPVEPEPA--PVEPPKPK--PVEK 114
                          90       100       110
                  ....*....|....*....|....*....|....
gi 578807238 1157 iPQTQPVPKVPQRVTAKPKTSPSPEVSyTTPAPK 1190
Cdd:PRK11633  115 -PKPKPKPQQKVEAPPAPKPEPKPVVE-EKAAPT 146
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
567-635 1.21e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 43.64  E-value: 1.21e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578807238  567 PALEPATIQPEPLVPTtASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVP 635
Cdd:PRK14950  362 PVPAPQPAKPTAAAPS-PVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAP 429
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
863-1189 1.34e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 43.41  E-value: 1.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   863 PEASTTLASKTSQRT-RRPRLRTKTTPRPEAPESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVP 941
Cdd:pfam17823   66 APAPVTLTKGTSAAHlNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAP 145
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   942 QTKlVPSTdlePGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----SPEVPQNKSVSVTGF 1017
Cdd:pfam17823  146 RAA-ACRA---NASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSApatlTPARGISTAATATGH 221
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  1018 EPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESP-KETIAPAKTDYVYPTAKAPLWPEEP 1096
Cdd:pfam17823  222 PAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPhARRLSPAKHMPSDTMARNPAAPMGA 301
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  1097 KTEVVESITYVSEPPETTlETSPLPSQSITLPSPDEPQ-----------TEPAPKQTPRAPPKP--KTSPRPRI----PQ 1159
Cdd:pfam17823  302 QAQGPIIQVSTDQPVHNT-AGEPTPSPSNTTLEPNTPKsvastnlavvtTTKAQAKEPSASPVPvlHTSMIPEVeatsPT 380
                          330       340       350
                   ....*....|....*....|....*....|
gi 578807238  1160 TQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 1189
Cdd:pfam17823  381 TQPSPLLPTQGAAGPGILLAPEQVATEATA 410
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
585-956 1.54e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.52  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  585 SKPSERPKTTHRPDAPQIQPGSKPPKqllpkPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTDIEPVTvrTEATVTT 664
Cdd:PTZ00449  537 SKESDEPKEGGKPGETKEGEVGKKPG-----PAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRS--AQRPTRP 609
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  665 LAPKTSQRTRTRRPRPKHKTTPRPETlqtkldfgPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEV-PQTK-LVPATILE 742
Cdd:PTZ00449  610 KSPKLPELLDIPKSPKRPESPKSPKR--------PPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFdPKFKeKFYDDYLD 681
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  743 PVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVP------ATIFEPV-SPIKEAPGTTFVPVTDLEPVTFRT 815
Cdd:PTZ00449  682 AAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPklprdeEFPFEPIgDPDAEQPDDIEFFTPPEEERTFFH 761
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  816 EIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPvpatvLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTPRpEAPES 895
Cdd:PTZ00449  762 ETPADTPLPDILAEEFKEEDIHAETGEPDEAMKRP-----DSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTDL-ESDAG 835
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  896 KPVPTAELKPVTLR-----------------------------------TETWVTTQAPKTSQRTRRPRPKTKTTPSPEV 940
Cdd:PTZ00449  836 RIAKDASGKIVKLKrsksfddlttveeaeemgaearkivvdddgteaddEDTHPPEEKHKSEVRRRRPPKKPSKPKKPSK 915
                         410
                  ....*....|....*.
gi 578807238  941 PQTKLVPSTDLEPGTL 956
Cdd:PTZ00449  916 PKKPKKPDSAFIPSII 931
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
818-986 2.10e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.94  E-value: 2.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  818 PATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTLRPEA-----STTLASKTSQRTRRPRLRTKTTPRPEA 892
Cdd:PRK12323  374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAaparrSPAPEALAAARQASARGPGGAPAPAPA 453
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  893 PESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPS-PEVPQTKLVPS-TDLEPGTLRTEAPKTMVVTTVL 970
Cdd:PRK12323  454 PAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPwEELPPEFASPApAQPDAAPAGWVAESIPDPATAD 533
                         170
                  ....*....|....*.
gi 578807238  971 EPDTFRTKFPETTLAP 986
Cdd:PRK12323  534 PDDAFETLAPAPAAAP 549
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
849-1166 2.27e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 42.75  E-value: 2.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  849 KPVPATVLEP-----VTLRPEASTTLAS----KTSQRTRRPRLRTKTT--PRPEAPESKPVPTAELKPvtlrtETWVTTQ 917
Cdd:PTZ00449  560 KPGPAKEHKPskiptLSKKPEFPKDPKHpkdpEEPKKPKRPRSAQRPTrpKSPKLPELLDIPKSPKRP-----ESPKSPK 634
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  918 APKTSQRTRRPR----PKT-KTTPSPEVPQTKLVPS------TDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAP 986
Cdd:PTZ00449  635 RPPPPQRPSSPErpegPKIiKSPKPPKSPKPPFDPKfkekfyDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP 714
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  987 KTQRTRRPRPRPKTTSSPEVPQNksvsvtgfEPVVHSTDaPGTTFALTELQTLILKpvtspslEMTESQPVSDVL----- 1061
Cdd:PTZ00449  715 FTTPRPLPPKLPRDEEFPFEPIG--------DPDAEQPD-DIEFFTPPEEERTFFH-------ETPADTPLPDILaeefk 778
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1062 -ESVTLSTESPKETIAPAKTDYVYPTAKAPLWPEEPK-----------------------------------TEVVESIT 1105
Cdd:PTZ00449  779 eEDIHAETGEPDEAMKRPDSPSEHEDKPPGDHPSLPKkrhrldglalsttdlesdagriakdasgkivklkrSKSFDDLT 858
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578807238 1106 YVSEPPETTLETSPLPSQSITLPSPDEpQTEPA------------PKQTPRAPPKPKTSPRPRIPQTQPVPKV 1166
Cdd:PTZ00449  859 TVEEAEEMGAEARKIVVDDDGTEADDE-DTHPPeekhksevrrrrPPKKPSKPKKPSKPKKPKKPDSAFIPSI 930
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
123-202 2.75e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 2.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  123 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 200
Cdd:cd00063     3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73

                  ..
gi 578807238  201 VK 202
Cdd:cd00063    74 VR 75
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1031-1241 2.85e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 2.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1031 FALTELQTLILKPVTSPSlemtESQPVSDVLESVTLSTE--SPKETIAPAKTDYVYPTAKAPLwPEEPKTEVVESITYVS 1108
Cdd:PRK12323  353 FTMTLLRMLAFRPGQSGG----GAGPATAAAAPVAQPAPaaAAPAAAAPAPAAPPAAPAAAPA-AAAAARAVAAAPARRS 427
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1109 EPPEttletsplPSQSITLPSPDEPQTEPAPkqTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA 1188
Cdd:PRK12323  428 PAPE--------ALAAARQASARGPGGAPAP--APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPP 497
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578807238 1189 PKDVLLPHKPYPEVSQSEPVLQPV---------------TFRFEPPKTTIAPLETRGIPFIPMISPSP 1241
Cdd:PRK12323  498 PWEELPPEFASPAPAQPDAAPAGWvaesipdpatadpddAFETLAPAPAAAPAPRAAAATEPVVAPRP 565
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
1110-1187 2.93e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.46  E-value: 2.93e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578807238 1110 PPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTP 1187
Cdd:PRK14971  391 QPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPVSKVSSLGP 468
PRK10263 PRK10263
DNA translocase FtsK; Provisional
412-702 3.20e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 42.38  E-value: 3.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  412 SSEKPWIVPTAKISEDSKVLQPQTAPQQTTsipstpkrrprpkpprtkPERTTSAGTITPK--IskSPEPTWTTPAPGKT 489
Cdd:PRK10263  328 TATQSWAAPVEPVTQTPPVASVDVPPAQPT------------------VAWQPVPGPQTGEpvI--APAPEGYPQQSQYA 387
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  490 QfislkpkiplsPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVPKSKPAL 569
Cdd:PRK10263  388 Q-----------PAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTF 456
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  570 EP-ATIQPEPLV--PTTASKPSERPKTTHRPDAPQIQPG------SKPP---------------KQLLPKPQTTAEPDMP 625
Cdd:PRK10263  457 APqSTYQTEQTYqqPAAQEPLYQQPQPVEQQPVVEPEPVveetkpARPPlyyfeeveekrarerEQLAAWYQPIPEPVKE 536
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578807238  626 PtksvsEPVPFETEAPSMTIVPTTDIEPVTVRTEATV--TTLAPKTSQRTRTRRPRPKHKTTPRPetlQTKLDFGPITP 702
Cdd:PRK10263  537 P-----EPIKSSLKAPSVAAVPPVEAAAAVSPLASGVkkATLATGAAATVAAPVFSLANSGGPRP---QVKEGIGPQLP 607
rne PRK10811
ribonuclease E; Reviewed
1117-1291 4.84e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.95  E-value: 4.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1117 TSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQrVTAKPKTSPSPEVSYTTPAPKDVLLPH 1196
Cdd:PRK10811  848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPV-VVAEPQPEEVVVVETTHPEVIAAPVTE 926
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1197 KPYPEVSQSEPVLQPVTFRFEP---------PKTTIAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPR 1267
Cdd:PRK10811  927 QPQVITESDVAVAQEVAEHAEPvvepqdetaDIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQV 1006
                         170       180       190
                  ....*....|....*....|....*....|.
gi 578807238 1268 TTELAKT-------TQAPHRFYTTVRPRTSD 1291
Cdd:PRK10811 1007 PEATVEHnhatapmTRAPAPEYVPEAPRHSD 1037
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
1131-1211 5.21e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 41.47  E-value: 5.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1131 DEPQTEPAPKQTPRAPPKPKTSPRP-RIPQTQPVPKVPQRVTAKPKTSPSPEVSYT----TPAPKDVLLPHKPYPEVSQS 1205
Cdd:PRK14954  374 VRNDGGVAPSPAGSPDVKKKAPEPDlPQPDRHPGPAKPEAPGARPAELPSPASAPTpeqqPPVARSAPLPPSPQASAPRN 453

                  ....*.
gi 578807238 1206 EPVLQP 1211
Cdd:PRK14954  454 VASGKP 459
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
654-967 6.03e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.10  E-value: 6.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   654 VTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKldfGPITPGTSSAPTTTTKRTRRPH-PKPKTTPHPEVPQ 732
Cdd:pfam17823   86 VTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSA---AQSLPAAIAALPSEAFSAPRAAaCRANASAAPRAAI 162
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   733 TKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTlspeelqtelvPATIFePVSPIKEAPGTTFVPVTDlepvT 812
Cdd:pfam17823  163 AAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSA-----------PATLT-PARGISTAATATGHPAAG----T 226
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   813 FRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVL---EPVTLRPEASTTLASKTSQRTRRPRLRTK---- 885
Cdd:pfam17823  227 ALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTInmgDPHARRLSPAKHMPSDTMARNPAAPMGAQaqgp 306
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   886 ------------TTPRPE-APESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVPQTKLVPSTDLE 952
Cdd:pfam17823  307 iiqvstdqpvhnTAGEPTpSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSMIPEVEATSPTTQPSPL 386
                          330
                   ....*....|....*
gi 578807238   953 PGTLRTEAPKTMVVT 967
Cdd:pfam17823  387 LPTQGAAGPGILLAP 401
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
496-722 6.77e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.40  E-value: 6.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  496 PKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRktkrpgrrprprprpKTTPSPEVPKSKPALEPATIQ 575
Cdd:PRK12323  374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAAR---------------AVAAAPARRSPAPEALAAARQ 438
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  576 PEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTDIEPVT 655
Cdd:PRK12323  439 ASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAP 518
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578807238  656 VRTEAtvttlapktsqrtrtrrprpkhKTTPRPETLQTKLDFGPITPGTSSAPTTTTKRTRRPHPKP 722
Cdd:PRK12323  519 AGWVA----------------------ESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAP 563
PRK10263 PRK10263
DNA translocase FtsK; Provisional
620-1192 6.77e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.22  E-value: 6.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  620 AEPDMPptksvSEPVPFETEAPSMtivPTTDIEPVT-VRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDFG 698
Cdd:PRK10263  337 VEPVTQ-----TPPVASVDVPPAQ---PTVAWQPVPgPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYY 408
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  699 PITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPqtklvpatILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEEL 778
Cdd:PRK10263  409 APAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQP--------VAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQ 480
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  779 QTELVPATIFEPVsPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATktskrTRPPRPRPKTTPSPQAPETKPVPATVLEP 858
Cdd:PRK10263  481 PQPVEQQPVVEPE-PVVEETKPARPPLYYFEEVEEKRAREREQLAA-----WYQPIPEPVKEPEPIKSSLKAPSVAAVPP 554
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  859 VTLRPeASTTLASKTSQRTrrprLRTKTTPRPEAPESKPVPTAELKPvtlRTETWVTTQAPKtSQRTRRPRPKTKTTPSP 938
Cdd:PRK10263  555 VEAAA-AVSPLASGVKKAT----LATGAAATVAAPVFSLANSGGPRP---QVKEGIGPQLPR-PKRIRVPTRRELASYGI 625
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238  939 EVPQTKLVPSTDLEPGTLRTEAPKTMVVTTV--LEPDTFRTKFPETTLAP--KTQRTRRPRPRPKTTSSPEVPQNKSVSV 1014
Cdd:PRK10263  626 KLPSQRAAEEKAREAQRNQYDSGDQYNDDEIdaMQQDELARQFAQTQQQRygEQYQHDVPVNAEDADAAAEAELARQFAQ 705
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1015 TGFEPVVHSTDAPGTTFALTELQtlilkpvTSPSLEMTESQPVSDVLESVTLSTESPKETIAPAktdyvyPTAKAPLWPE 1094
Cdd:PRK10263  706 TQQQRYSGEQPAGANPFSLDDFE-------FSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQ------QQYQQPQQPV 772
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238 1095 EPKTEVVESITYVSEPPETTLETSPLPSQsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 1174
Cdd:PRK10263  773 APQPQYQQPQQPVAPQPQYQQPQQPVAPQ----PQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHP 848
                         570       580       590
                  ....*....|....*....|....*....|.
gi 578807238 1175 -------------KTSPSPEVSYTTPAPKDV 1192
Cdd:PRK10263  849 llmrngdsrplhkPTTPLPSLDLLTPPPSEV 879
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
510-949 7.62e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.06  E-value: 7.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   510 APEPQTLLPSQSTIGPETPGTK---PSTTLAPRKTKRPGRRPRPRPRPKTTpSPEVPKSKPALEPATIQPEPLVPTTASK 586
Cdd:pfam05109  424 APESTTTSPTLNTTGFAAPNTTtglPSSTHVPTNLTAPASTGPTVSTADVT-SPTPAGTTSGASPVTPSPSPRDNGTESK 502
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   587 PSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEP--DMPPTKSVSEPVPFETEAPSMTIVPTTDiepvtvrteATVTT 664
Cdd:pfam05109  503 APDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTlgKTSPTSAVTTPTPNATSPTPAVTTPTPN---------ATIPT 573
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   665 LApKTSqrtrtrrprpkhkttprpetlqtkldfgPITPGTSSAPTTTTKRTRRPHPKPKTTPHPevpqtklVPATILEPV 744
Cdd:pfam05109  574 LG-KTS----------------------------PTSAVTTPTPNATSPTVGETSPQANTTNHT-------LGGTSSTPV 617
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   745 LRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIFEPVSPIkeaPGTTFVPVTDLEPVTFRTEIPATTLAT 824
Cdd:pfam05109  618 VTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHM---PLLTSAHPTGGENITQVTPASTSTHHV 694
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578807238   825 KTSkRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTK------------TTPRPEA 892
Cdd:pfam05109  695 STS-SPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTAVPTVTSTggkansttggkhTTGHGAR 773
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 578807238   893 PESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVPQTKLVPST 949
Cdd:pfam05109  774 TSTEPTTDYGGDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPPVTTAQATVPVPPT 830
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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