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Conserved domains on  [gi|578178742|gb|EUL39075|]
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methyltransferase type 11 [Enterobacter hormaechei subsp. hoffmannii UCI 50]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 10789277)

class I SAM-dependent methyltransferase is an enzyme that uses S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyl transfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:0008168|GO:1904047
PubMed:  12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 36-152 1.30e-40

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


:

Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 136.66  E-value: 1.30e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  36 RLGERLAAFPDAHVLDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLNnVTTRQGYAESLPFEDASFEAV 115
Cdd:COG2226   13 ALLAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGLN-VEFVVGDAEDLPFPDGSFDLV 91

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 578178742 116 ISRYSAHHWHDVGQALREVKRVLKPGGIFIIMDVMSP 152
Cdd:COG2226   92 ISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPP 128
 
Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 36-152 1.30e-40

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 136.66  E-value: 1.30e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  36 RLGERLAAFPDAHVLDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLNnVTTRQGYAESLPFEDASFEAV 115
Cdd:COG2226   13 ALLAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGLN-VEFVVGDAEDLPFPDGSFDLV 91

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 578178742 116 ISRYSAHHWHDVGQALREVKRVLKPGGIFIIMDVMSP 152
Cdd:COG2226   92 ISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPP 128
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 50-146 1.30e-32

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 114.68  E-value: 1.30e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   50 LDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLNNVttrQGYAESLPFEDASFEAVISRYSAHHWHDVGQ 129
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGLTFV---VGDAEDLPFPDNSFDLVLSSEVLHHVEDPER 77

                          90
                  ....*....|....*..
gi 578178742  130 ALREVKRVLKPGGIFII 146
Cdd:pfam08241  78 ALREIARVLKPGGILII 94
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 1-164 1.11e-25

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 101.00  E-value: 1.11e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   1 MTTTHSHHDNVEKQFGSQASAY------LSSAVHASGRDLVRlgERLAAFPDAHVLDLGCGAGHASFTAAQQV---AQVT 71
Cdd:PRK00216   3 TVAEEEKQEKVAEMFDSIAPKYdlmndlLSFGLHRVWRRKTI--KWLGVRPGDKVLDLACGTGDLAIALAKAVgktGEVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  72 AYDLSSQMLDVVAEAAKAKGL-NNVTTRQGYAESLPFEDASFEAV-ISrYSAHHWHDVGQALREVKRVLKPGGIFIIMDV 149
Cdd:PRK00216  81 GLDFSEGMLAVGREKLRDLGLsGNVEFVQGDAEALPFPDNSFDAVtIA-FGLRNVPDIDKALREMYRVLKPGGRLVILEF 159

                        170
                 ....*....|....*....
gi 578178742 150 MSPGHP----VRNIWLQTV 164
Cdd:PRK00216 160 SKPTNPplkkAYDFYLFKV 178
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 11-164 1.59e-24

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 97.33  E-value: 1.59e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   11 VEKQFGSQASAY------LSSAVHASGRDlvRLGERLAAFPDAHVLDLGCGAGHASFTAAQ---QVAQVTAYDLSSQMLD 81
Cdd:TIGR01934   1 VQEMFDRIAPKYdllndlLSFGLHRLWRR--RAVKLIGVFKGQKVLDVACGTGDLAIELAKsapDRGKVTGVDFSSEMLE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   82 VVAEaaKAKGLNNVTTRQGYAESLPFEDASFEAVISRYSAHHWHDVGQALREVKRVLKPGGIFIIMDVMSPGH----PVR 157
Cdd:TIGR01934  79 VAKK--KSELPLNIEFIQADAEALPFEDNSFDAVTIAFGLRNVTDIQKALREMYRVLKPGGRLVILEFSKPANallkKFY 156


                  ....*..
gi 578178742  158 NIWLQTV 164
Cdd:TIGR01934 157 KFYLKNV 163
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 49-149 3.47e-20

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 82.86  E-value: 3.47e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  49 VLDLGCGAGHASFTAAQQ-VAQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGYAESLPF-EDASFEAVISRYSAHHWH- 125
Cdd:cd02440    2 VLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPeADESFDVIISDPPLHHLVe 81

                         90       100
                 ....*....|....*....|....
gi 578178742 126 DVGQALREVKRVLKPGGIFIIMDV 149
Cdd:cd02440   82 DLARFLEEARRLLKPGGVLVLTLV 105
PKS_MT smart00828
Methyltransferase in polyketide synthase (PKS) enzymes;
48-236 5.48e-06

Methyltransferase in polyketide synthase (PKS) enzymes;


Pssm-ID: 214839 [Multi-domain]  Cd Length: 224  Bit Score: 46.26  E-value: 5.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742    48 HVLDLGCGAGHASFTAAQQVA--QVTAYDLSSQMLDVVAEAAKAKGLNN-VTTRQGYAESLPFEDaSFEAVISRYSAHHW 124
Cdd:smart00828   2 RVLDFGCGYGSDLIDLAERHPhlQLHGYTISPEQAEVGRERIRALGLQGrIRIFYRDSAKDPFPD-TYDLVFGFEVIHHI 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   125 HDVGQALREVKRVLKPGGIFIIMDVMSpgHPVRNIWLQtvealrdTSHVQNYSSGEWLTFITEAGLISRSLITdrLSLEF 204
Cdd:smart00828  81 KDKMDLFSNISRHLKDGGHLVLADFIA--NLLSAIEHE-------ETTSYLVTREEWAELLARNNLRVVEGVD--ASLEI 149

                          170       180       190
                   ....*....|....*....|....*....|..
gi 578178742   205 TSWiarMRTPEALTQAIRLYQESASADVKAYF 236
Cdd:smart00828 150 ANF---LYDPGFEDNLERLYQDDLDEVTKRHF 178
 
Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 36-152 1.30e-40

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 136.66  E-value: 1.30e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  36 RLGERLAAFPDAHVLDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLNnVTTRQGYAESLPFEDASFEAV 115
Cdd:COG2226   13 ALLAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGLN-VEFVVGDAEDLPFPDGSFDLV 91

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 578178742 116 ISRYSAHHWHDVGQALREVKRVLKPGGIFIIMDVMSP 152
Cdd:COG2226   92 ISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPP 128
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 50-146 1.30e-32

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 114.68  E-value: 1.30e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   50 LDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLNNVttrQGYAESLPFEDASFEAVISRYSAHHWHDVGQ 129
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGLTFV---VGDAEDLPFPDNSFDLVLSSEVLHHVEDPER 77

                          90
                  ....*....|....*..
gi 578178742  130 ALREVKRVLKPGGIFII 146
Cdd:pfam08241  78 ALREIARVLKPGGILII 94
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 49-142 3.46e-31

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 111.12  E-value: 3.46e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   49 VLDLGCGAGHASFTAAQQV-AQVTAYDLSSQMLDVVAEAAKAKGLNnVTTRQGYAESLPFEDASFEAVISRYSAHHWH-- 125
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGgARVTGVDLSPEMLERARERAAEAGLN-VEFVQGDAEDLPFPDGSFDLVVSSGVLHHLPdp 79

                          90
                  ....*....|....*..
gi 578178742  126 DVGQALREVKRVLKPGG 142
Cdd:pfam13649  80 DLEAALREIARVLKPGG 96
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 32-148 6.58e-28

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 103.56  E-value: 6.58e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  32 RDLVRLGERLAAfPDAHVLDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAkglNNVTTRQGYAESLPFEDAS 111
Cdd:COG2227   12 RRLAALLARLLP-AGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAE---LNVDFVQGDLEDLPLEDGS 87

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 578178742 112 FEAVISRYSAHHWHDVGQALREVKRVLKPGGIFIIMD 148
Cdd:COG2227   88 FDLVICSEVLEHLPDPAALLRELARLLKPGGLLLLST 124
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 1-164 1.11e-25

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 101.00  E-value: 1.11e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   1 MTTTHSHHDNVEKQFGSQASAY------LSSAVHASGRDLVRlgERLAAFPDAHVLDLGCGAGHASFTAAQQV---AQVT 71
Cdd:PRK00216   3 TVAEEEKQEKVAEMFDSIAPKYdlmndlLSFGLHRVWRRKTI--KWLGVRPGDKVLDLACGTGDLAIALAKAVgktGEVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  72 AYDLSSQMLDVVAEAAKAKGL-NNVTTRQGYAESLPFEDASFEAV-ISrYSAHHWHDVGQALREVKRVLKPGGIFIIMDV 149
Cdd:PRK00216  81 GLDFSEGMLAVGREKLRDLGLsGNVEFVQGDAEALPFPDNSFDAVtIA-FGLRNVPDIDKALREMYRVLKPGGRLVILEF 159

                        170
                 ....*....|....*....
gi 578178742 150 MSPGHP----VRNIWLQTV 164
Cdd:PRK00216 160 SKPTNPplkkAYDFYLFKV 178
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 11-164 1.59e-24

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 97.33  E-value: 1.59e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   11 VEKQFGSQASAY------LSSAVHASGRDlvRLGERLAAFPDAHVLDLGCGAGHASFTAAQ---QVAQVTAYDLSSQMLD 81
Cdd:TIGR01934   1 VQEMFDRIAPKYdllndlLSFGLHRLWRR--RAVKLIGVFKGQKVLDVACGTGDLAIELAKsapDRGKVTGVDFSSEMLE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   82 VVAEaaKAKGLNNVTTRQGYAESLPFEDASFEAVISRYSAHHWHDVGQALREVKRVLKPGGIFIIMDVMSPGH----PVR 157
Cdd:TIGR01934  79 VAKK--KSELPLNIEFIQADAEALPFEDNSFDAVTIAFGLRNVTDIQKALREMYRVLKPGGRLVILEFSKPANallkKFY 156


                  ....*..
gi 578178742  158 NIWLQTV 164
Cdd:TIGR01934 157 KFYLKNV 163
PRK08317 PRK08317
hypothetical protein; Provisional
 39-207 7.22e-24

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 96.16  E-value: 7.22e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  39 ERLAAFPDAHVLDLGCGAGHASFTAAQQV---AQVTAYDLSSQMLDVVAEAAKAKGLNnVTTRQGYAESLPFEDASFEAV 115
Cdd:PRK08317  13 ELLAVQPGDRVLDVGCGPGNDARELARRVgpeGRVVGIDRSEAMLALAKERAAGLGPN-VEFVRGDADGLPFPDGSFDAV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742 116 ISRYSAHHWHDVGQALREVKRVLKPGGIFIIMD------VMSPGHPVR-----NIWLqtvealrdtSHVQNYSSGEWL-T 183
Cdd:PRK08317  92 RSDRVLQHLEDPARALAEIARVLRPGGRVVVLDtdwdtlVWHSGDRALmrkilNFWS---------DHFADPWLGRRLpG 162

                        170       180
                 ....*....|....*....|....*....
gi 578178742 184 FITEAGLIS-----RSLITDRLSLEFTSW 207
Cdd:PRK08317 163 LFREAGLTDievepYTLIETDLKEADKGF 191
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 45-189 6.90e-22

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 88.63  E-value: 6.90e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   45 PDAHVLDLGCGAGHASFTAAQQV---AQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGYAESLP--FEDASFEAVISRY 119
Cdd:pfam13847   3 KGMRVLDLGCGTGHLSFELAEELgpnAEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEELPelLEDDKFDVVISNC 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578178742  120 SAHHWHDVGQALREVKRVLKPGGIFIIMDVmspghpvrNIWLQTVEALRDTSHVQN------YSSGEWLTFITEAG 189
Cdd:pfam13847  83 VLNHIPDPDKVLQEILRVLKPGGRLIISDP--------DSLAELPAHVKEDSTYYAgcvggaILKKKLYELLEEAG 150
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 45-152 2.43e-20

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 85.74  E-value: 2.43e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  45 PDAHVLDLGCGAG-HASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQG-YAESLPFEDASFEAVISRYSAH 122
Cdd:COG0500   26 KGGRVLDLGCGTGrNLLALAARFGGRVIGIDLSPEAIALARARAAKAGLGNVEFLVAdLAELDPLPAESFDLVVAFGVLH 105

                         90       100       110
                 ....*....|....*....|....*....|..
gi 578178742 123 HW--HDVGQALREVKRVLKPGGIFIIMDVMSP 152
Cdd:COG0500  106 HLppEEREALLRELARALKPGGVLLLSASDAA 137
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 34-146 2.86e-20

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 84.60  E-value: 2.86e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  34 LVRLGERLAAFPDAHVLDLGCGAGHASFTAAQQV-AQVTAYDLSSQMLDVVAEAAKAKGL-NNVTTRQGYAESLPFeDAS 111
Cdd:COG2230   40 LDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYgVRVTGVTLSPEQLEYARERAAEAGLaDRVEVRLADYRDLPA-DGQ 118

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 578178742 112 FEAVISRYSAHH--WHDVGQALREVKRVLKPGGIFII 146
Cdd:COG2230  119 FDAIVSIGMFEHvgPENYPAYFAKVARLLKPGGRLLL 155
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 49-149 3.47e-20

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 82.86  E-value: 3.47e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  49 VLDLGCGAGHASFTAAQQ-VAQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGYAESLPF-EDASFEAVISRYSAHHWH- 125
Cdd:cd02440    2 VLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPeADESFDVIISDPPLHHLVe 81

                         90       100
                 ....*....|....*....|....
gi 578178742 126 DVGQALREVKRVLKPGGIFIIMDV 149
Cdd:cd02440   82 DLARFLEEARRLLKPGGVLVLTLV 105
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
39-196 1.23e-19

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 83.51  E-value: 1.23e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  39 ERLAAFPDAHVLDLGCGAGHASFTAAQQVAQVTAYDLSSQMLdvvaEAAKAKGLNNVTTRQGYAEsLPFEDASFEAVISR 118
Cdd:COG4976   40 ARLPPGPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEML----AKAREKGVYDRLLVADLAD-LAEPDGRFDLIVAA 114

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578178742 119 YSAHHWHDVGQALREVKRVLKPGGIFIImdvmspghpvrniwlqTVEALrDTSHVQNYSSGEWLTFITEAGLISRSLI 196
Cdd:COG4976  115 DVLTYLGDLAAVFAGVARALKPGGLFIF----------------SVEDA-DGSGRYAHSLDYVRDLLAAAGFEVPGLL 175
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
45-146 1.23e-18

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 78.33  E-value: 1.23e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  45 PDAHVLDLGCGAGHASFTAAQQV--AQVTAYDLSSQMLdvvaEAAKAKgLNNVTTRQGYAESLPFEdASFEAVISRYSAH 122
Cdd:COG4106    1 PPRRVLDLGCGTGRLTALLAERFpgARVTGVDLSPEML----ARARAR-LPNVRFVVADLRDLDPP-EPFDLVVSNAALH 74

                         90       100
                 ....*....|....*....|....
gi 578178742 123 HWHDVGQALREVKRVLKPGGIFII 146
Cdd:COG4106   75 WLPDHAALLARLAAALAPGGVLAV 98
arsM PRK11873
arsenite methyltransferase;
49-149 4.58e-18

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 81.15  E-value: 4.58e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  49 VLDLGCGAGHASFTAAQQVA---QVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGYAESLPFEDASFEAVIS----RYSA 121
Cdd:PRK11873  81 VLDLGSGGGFDCFLAARRVGptgKVIGVDMTPEMLAKARANARKAGYTNVEFRLGEIEALPVADNSVDVIISncviNLSP 160

                         90       100
                 ....*....|....*....|....*...
gi 578178742 122 hhwhDVGQALREVKRVLKPGGIFIIMDV 149
Cdd:PRK11873 161 ----DKERVFKEAFRVLKPGGRFAISDV 184
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 50-144 9.76e-17

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 73.17  E-value: 9.76e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   50 LDLGCGAGHASFTAAQQV--AQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGYAESLPFED-ASFEAVISRYSAHHWHD 126
Cdd:pfam08242   1 LEIGCGTGTLLRALLEALpgLEYTGLDISPAALEAARERLAALGLLNAVRVELFQLDLGELDpGSFDVVVASNVLHHLAD 80

                          90
                  ....*....|....*...
gi 578178742  127 VGQALREVKRVLKPGGIF 144
Cdd:pfam08242  81 PRAVLRNIRRLLKPGGVL 98
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 15-145 1.63e-16

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 76.17  E-value: 1.63e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   15 FGSQASAYLSSAV--HASGRDLVRLGERLAAFPDAHVLDLGCGAGHASFTAAQQVAQV--TAYDLSSQMLDVVAEAAKAk 90
Cdd:TIGR02072   2 FNKAAKTYDRHAKiqREMAKRLLALLKEKGIFIPASVLDIGCGTGYLTRALLKRFPQAefIALDISAGMLAQAKTKLSE- 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 578178742   91 glnNVTTRQGYAESLPFEDASFEAVISRySAHHW-HDVGQALREVKRVLKPGGIFI 145
Cdd:TIGR02072  81 ---NVQFICGDAEKLPLEDSSFDLIVSN-LALQWcDDLSQALSELARVLKPGGLLA 132
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
11-155 2.63e-16

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 75.55  E-value: 2.63e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   11 VEKQFGSQASAY------LSSAVHASGRDLVRlgERLAAFPDAHVLDLGCGAGHASFTAAQQV---AQVTAYDLSSQMLD 81
Cdd:pfam01209   4 VGDVFSSVASKYdlmndvISFGIHRLWKDFTM--KCMGVKRGNKFLDVAGGTGDWTFGLSDSAgssGKVVGLDINENMLK 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578178742   82 VVAEAAKAKGLNNVTTRQGYAESLPFEDASFEAVISRYSAHHWHDVGQALREVKRVLKPGGIFIIMDVMSPGHP 155
Cdd:pfam01209  82 EGEKKAKEEGKYNIEFLQGNAEELPFEDDSFDIVTISFGLRNFPDYLKVLKEAFRVLKPGGRVVCLEFSKPENP 155
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 32-190 6.58e-13

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 64.76  E-value: 6.58e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   32 RDLVRLGERLAAFPDAH--VLDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLnnvttrqgYAESLPFED 109
Cdd:pfam13489   7 RLLADLLLRLLPKLPSPgrVLDFGCGTGIFLRLLRAQGFSVTGVDPSPIAIERALLNVRFDQF--------DEQEAAVPA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  110 ASFEAVISRYSAHHWHDVGQALREVKRVLKPGGIFIIMDVMSPGHpvRNIWLQTVEALRDTS-HVQNYSSGEWLTFITEA 188
Cdd:pfam13489  79 GKFDVIVAREVLEHVPDPPALLRQIAALLKPGGLLLLSTPLASDE--ADRLLLEWPYLRPRNgHISLFSARSLKRLLEEA 156


                  ..
gi 578178742  189 GL 190
Cdd:pfam13489 157 GF 158
PRK10258 PRK10258
biotin biosynthesis protein BioC; Provisional
 11-142 7.03e-13

biotin biosynthesis protein BioC; Provisional


Pssm-ID: 182340 [Multi-domain]  Cd Length: 251  Bit Score: 66.32  E-value: 7.03e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  11 VEKQ-----FGSQASAYLSSAvhasgrDLVR-----LGERLAAFPDAHVLDLGCGAGHASFTAAQQVAQVTAYDLSSQML 80
Cdd:PRK10258   4 VNKQaiaaaFGRAAAHYEQHA------ELQRqsadaLLAMLPQRKFTHVLDAGCGPGWMSRYWRERGSQVTALDLSPPML 77

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578178742  81 DVVAEAAKAKglnnvTTRQGYAESLPFEDASFEAVISRYSAHHWHDVGQALREVKRVLKPGG 142
Cdd:PRK10258  78 AQARQKDAAD-----HYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPGG 134
PLN02233 PLN02233
ubiquinone biosynthesis methyltransferase
 49-156 3.58e-12

ubiquinone biosynthesis methyltransferase


Pssm-ID: 177877 [Multi-domain]  Cd Length: 261  Bit Score: 64.53  E-value: 3.58e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  49 VLDLGCGAGHASFTAAQQVA---QVTAYDLSSQMLDVVAEAAKAKG---LNNVTTRQGYAESLPFEDASFEAVISRYSAH 122
Cdd:PLN02233  77 VLDLCCGSGDLAFLLSEKVGsdgKVMGLDFSSEQLAVAASRQELKAkscYKNIEWIEGDATDLPFDDCYFDAITMGYGLR 156

                         90       100       110
                 ....*....|....*....|....*....|....
gi 578178742 123 HWHDVGQALREVKRVLKPGGIFIIMDVMSPGHPV 156
Cdd:PLN02233 157 NVVDRLKAMQEMYRVLKPGSRVSILDFNKSTQPF 190
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 41-146 1.89e-11

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 61.36  E-value: 1.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  41 LAAFPDA---HVLDLGCGAGHASFTAAQQ--VAQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGYAESlPFEDASFEAV 115
Cdd:COG2813   42 LEHLPEPlggRVLDLGCGYGVIGLALAKRnpEARVTLVDVNARAVELARANAAANGLENVEVLWSDGLS-GVPDGSFDLI 120

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 578178742 116 IS----RYSAHHWHDVGQAL-REVKRVLKPGGIFII 146
Cdd:COG2813  121 LSnppfHAGRAVDKEVAHALiADAARHLRPGGELWL 156
COG4627 COG4627
Predicted SAM-depedendent methyltransferase [General function prediction only];
50-146 8.83e-10

Predicted SAM-depedendent methyltransferase [General function prediction only];


Pssm-ID: 443666 [Multi-domain]  Cd Length: 161  Bit Score: 56.03  E-value: 8.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  50 LDLGCG-AGHASFTAAQQVAQVTAydlssqmlDVVAEAAKAkglnnvttrqgyaesLPFEDASFEAVisrYSAH---H-- 123
Cdd:COG4627    7 LNIGCGpKRLPGWLNVDIVPAPGV--------DIVGDLTDP---------------LPFPDNSVDAI---YSSHvleHld 60

                         90       100
                 ....*....|....*....|...
gi 578178742 124 WHDVGQALREVKRVLKPGGIFII 146
Cdd:COG4627   61 YEEAPLALKECYRVLKPGGILRI 83
PLN02490 PLN02490
MPBQ/MSBQ methyltransferase
 45-161 2.63e-09

MPBQ/MSBQ methyltransferase


Pssm-ID: 215270 [Multi-domain]  Cd Length: 340  Bit Score: 56.82  E-value: 2.63e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  45 PDAHVLDLGCGAGHASFTAAQQV--AQVTAYDLSSQMLdvvAEAAKAKGLNNVTTRQGYAESLPFEDASFEAVISRYSAH 122
Cdd:PLN02490 113 RNLKVVDVGGGTGFTTLGIVKHVdaKNVTILDQSPHQL---AKAKQKEPLKECKIIEGDAEDLPFPTDYADRYVSAGSIE 189

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 578178742 123 HWHDVGQALREVKRVLKPGGIFIImdvMSPGHPvrNIWL 161
Cdd:PLN02490 190 YWPDPQRGIKEAYRVLKIGGKACL---IGPVHP--TFWL 223
PLN02244 PLN02244
tocopherol O-methyltransferase
 49-146 1.11e-08

tocopherol O-methyltransferase


Pssm-ID: 215135 [Multi-domain]  Cd Length: 340  Bit Score: 54.75  E-value: 1.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  49 VLDLGCGAGHAS-FTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLNN-VTTRQGYAESLPFEDASFEAVISRYSAHHWHD 126
Cdd:PLN02244 122 IVDVGCGIGGSSrYLARKYGANVKGITLSPVQAARANALAAAQGLSDkVSFQVADALNQPFEDGQFDLVWSMESGEHMPD 201

                         90       100
                 ....*....|....*....|
gi 578178742 127 VGQALREVKRVLKPGGIFII 146
Cdd:PLN02244 202 KRKFVQELARVAAPGGRIII 221
PRK11036 PRK11036
tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM;
33-147 2.43e-08

tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM;


Pssm-ID: 182918  Cd Length: 255  Bit Score: 53.43  E-value: 2.43e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  33 DLVRLgerLAAFPDA--HVLDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGL-NNVTTRQGYAESL---- 105
Cdd:PRK11036  33 DLDRL---LAELPPRplRVLDAGGGEGQTAIKLAELGHQVILCDLSAEMIQRAKQAAEAKGVsDNMQFIHCAAQDIaqhl 109

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 578178742 106 --PFEDASFEAVIsrysahHW-HDVGQALREVKRVLKPGGIFIIM 147
Cdd:PRK11036 110 etPVDLILFHAVL------EWvADPKSVLQTLWSVLRPGGALSLM 148
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 37-146 3.04e-08

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 51.82  E-value: 3.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   37 LGERLAAFPDAHVLDLGCGAGHASFTAAQ--QVAQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQ--GYAEslpFEDASF 112
Cdd:pfam05175  23 LLEHLPKDLSGKVLDLGCGAGVLGAALAKesPDAELTMVDINARALESARENLAANGLENGEVVAsdVYSG---VEDGKF 99

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 578178742  113 EAVIS----RYSAHHWHDVGQAL-REVKRVLKPGGIFII 146
Cdd:pfam05175 100 DLIISnppfHAGLATTYNVAQRFiADAKRHLRPGGELWI 138
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 45-116 1.06e-07

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 51.38  E-value: 1.06e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578178742  45 PDAHVLDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLN-NVTTRQGYAESLpfeDASFEAVI 116
Cdd:PRK07580  63 TGLRILDAGCGVGSLSIPLARRGAKVVASDISPQMVEEARERAPEAGLAgNITFEVGDLESL---LGRFDTVV 132
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 41-146 1.89e-07

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 50.53  E-value: 1.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  41 LAAFPDA----HVLDLGCGAGHASFTAAQQV--AQVTAYDLSSQMLDVVAEAAKAKGLNN-VTTRQG----YAEslPFED 109
Cdd:COG4123   29 LAAFAPVkkggRVLDLGTGTGVIALMLAQRSpgARITGVEIQPEAAELARRNVALNGLEDrITVIHGdlkeFAA--ELPP 106

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 578178742 110 ASFEAVIS-----------------RYSAHH-----WHDVgqaLREVKRVLKPGGIFII 146
Cdd:COG4123  107 GSFDLVVSnppyfkagsgrkspdeaRAIARHedaltLEDL---IRAAARLLKPGGRFAL 162
PRK05785 PRK05785
hypothetical protein; Provisional
 32-147 6.69e-07

hypothetical protein; Provisional


Pssm-ID: 235607 [Multi-domain]  Cd Length: 226  Bit Score: 48.92  E-value: 6.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  32 RDLVRLGERLAAFPdAHVLDLGCGAGHASFT-AAQQVAQVTAYDLSSQMLDvvaeaakakgLNNVTTR--QGYAESLPFE 108
Cdd:PRK05785  39 AELVKTILKYCGRP-KKVLDVAAGKGELSYHfKKVFKYYVVALDYAENMLK----------MNLVADDkvVGSFEALPFR 107

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 578178742 109 DASFEAVISRYSAHHWHDVGQALREVKRVLKPGGIFIIM 147
Cdd:PRK05785 108 DKSFDVVMSSFALHASDNIEKVIAEFTRVSRKQVGFIAM 146
rrmA PRK11088
23S rRNA methyltransferase A; Provisional
 47-153 6.84e-07

23S rRNA methyltransferase A; Provisional


Pssm-ID: 236841 [Multi-domain]  Cd Length: 272  Bit Score: 49.14  E-value: 6.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  47 AHVLDLGCGAGHASFTAAQQVAQVTAYDLssQMLDVVAEAAK--AKGLNNVTTRQGYAESLPFEDASFEAVISRYS---A 121
Cdd:PRK11088  87 TALLDIGCGEGYYTHALADALPEITTMQL--FGLDISKVAIKyaAKRYPQVTFCVASSHRLPFADQSLDAIIRIYApckA 164

                         90       100       110
                 ....*....|....*....|....*....|..
gi 578178742 122 hhwhdvgqalREVKRVLKPGGIFIimdVMSPG 153
Cdd:PRK11088 165 ----------EELARVVKPGGIVI---TVTPG 183
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 49-147 1.36e-06

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 47.25  E-value: 1.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  49 VLDLGCGAGhasfT----AAQQVAQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGYAESLPFEDASFEAVIS-----RY 119
Cdd:COG1041   30 VLDPFCGTG----TilieAGLLGRRVIGSDIDPKMVEGARENLEHYGYEDADVIRGDARDLPLADESVDAIVTdppygRS 105

                         90       100       110
                 ....*....|....*....|....*....|..
gi 578178742 120 SAHHWHD----VGQALREVKRVLKPGGIFIIM 147
Cdd:COG1041  106 SKISGEEllelYEKALEEAARVLKPGGRVVIV 137
TrmA COG2265
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ...
 39-116 2.75e-06

tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441866 [Multi-domain]  Cd Length: 377  Bit Score: 47.86  E-value: 2.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  39 ERLAAFPDAHVLDLGCGAGhaSFTA--AQQVAQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGYAE-SLP--FEDASFE 113
Cdd:COG2265  227 EWLDLTGGERVLDLYCGVG--TFALplARRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEeVLPelLWGGRPD 304


                 ...
gi 578178742 114 AVI 116
Cdd:COG2265  305 VVV 307
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
39-145 2.79e-06

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 46.95  E-value: 2.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  39 ERLAAF---------PDAHVLDLGCGAGHASFTAAQQVA-QVTAYDLSSQMLDVVAEAAKAKGLN-NVTTRQGYAESLPF 107
Cdd:COG4076   20 ERNDAFkaaiervvkPGDVVLDIGTGSGLLSMLAARAGAkKVYAVEVNPDIAAVARRIIAANGLSdRITVINADATDLDL 99

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 578178742 108 EDAsFEAVISrysahHWHDVGqALRE---------VKRVLKPGGIFI 145
Cdd:COG4076  100 PEK-ADVIIS-----EMLDTA-LLDEgqvpilnhaRKRLLKPGGRII 139
PLN02336 PLN02336
phosphoethanolamine N-methyltransferase
 45-155 4.78e-06

phosphoethanolamine N-methyltransferase


Pssm-ID: 177970 [Multi-domain]  Cd Length: 475  Bit Score: 47.05  E-value: 4.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  45 PDAHVLDLGCGAGHASFTAAQQV-AQVTAYDLSSQMLDVVAEaaKAKGLN-NVTTRQGYAESLPFEDASFEAVISRYSAH 122
Cdd:PLN02336 266 PGQKVLDVGCGIGGGDFYMAENFdVHVVGIDLSVNMISFALE--RAIGRKcSVEFEVADCTKKTYPDNSFDVIYSRDTIL 343

                         90       100       110
                 ....*....|....*....|....*....|....
gi 578178742 123 HWHDVGQALREVKRVLKPGGIFIIMD-VMSPGHP 155
Cdd:PLN02336 344 HIQDKPALFRSFFKWLKPGGKVLISDyCRSPGTP 377
PKS_MT smart00828
Methyltransferase in polyketide synthase (PKS) enzymes;
48-236 5.48e-06

Methyltransferase in polyketide synthase (PKS) enzymes;


Pssm-ID: 214839 [Multi-domain]  Cd Length: 224  Bit Score: 46.26  E-value: 5.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742    48 HVLDLGCGAGHASFTAAQQVA--QVTAYDLSSQMLDVVAEAAKAKGLNN-VTTRQGYAESLPFEDaSFEAVISRYSAHHW 124
Cdd:smart00828   2 RVLDFGCGYGSDLIDLAERHPhlQLHGYTISPEQAEVGRERIRALGLQGrIRIFYRDSAKDPFPD-TYDLVFGFEVIHHI 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   125 HDVGQALREVKRVLKPGGIFIIMDVMSpgHPVRNIWLQtvealrdTSHVQNYSSGEWLTFITEAGLISRSLITdrLSLEF 204
Cdd:smart00828  81 KDKMDLFSNISRHLKDGGHLVLADFIA--NLLSAIEHE-------ETTSYLVTREEWAELLARNNLRVVEGVD--ASLEI 149

                          170       180       190
                   ....*....|....*....|....*....|..
gi 578178742   205 TSWiarMRTPEALTQAIRLYQESASADVKAYF 236
Cdd:smart00828 150 ANF---LYDPGFEDNLERLYQDDLDEVTKRHF 178
PRK14103 PRK14103
trans-aconitate 2-methyltransferase; Provisional
 20-93 7.08e-06

trans-aconitate 2-methyltransferase; Provisional


Pssm-ID: 184509  Cd Length: 255  Bit Score: 45.84  E-value: 7.08e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578178742  20 SAYLSSAVHaSGRDLVRLGERLAAFPDAHVLDLGCGAGHASFTAAQQ--VAQVTAYDLSSQMLdvvaEAAKAKGLN 93
Cdd:PRK14103   5 DVYLAFADH-RGRPFYDLLARVGAERARRVVDLGCGPGNLTRYLARRwpGAVIEALDSSPEMV----AAARERGVD 75
PLN02232 PLN02232
ubiquinone biosynthesis methyltransferase
 74-148 3.45e-05

ubiquinone biosynthesis methyltransferase


Pssm-ID: 165876  Cd Length: 160  Bit Score: 43.14  E-value: 3.45e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578178742  74 DLSSQMLDVVA--EAAKAKGLNN-VTTRQGYAESLPFEDASFEAVISRYSAHHWHDVGQALREVKRVLKPGGIFIIMD 148
Cdd:PLN02232   4 DFSSEQLAVAAtrQSLKARSCYKcIEWIEGDAIDLPFDDCEFDAVTMGYGLRNVVDRLRAMKEMYRVLKPGSRVSILD 81
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 44-170 4.23e-05

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 43.61  E-value: 4.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  44 FPDAHVLDlgCGAGHASFTA--AQQVA---QVTAYDLSSQMLDVVAEAAKAKGL-NNVTTRQGYAESlPFEDASFEAVIS 117
Cdd:COG2519   90 FPGARVLE--AGTGSGALTLalARAVGpegKVYSYERREDFAEIARKNLERFGLpDNVELKLGDIRE-GIDEGDVDAVFL 166

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742 118 rysahhwhDVGQ---ALREVKRVLKPGGIFII----MDVMSpghpvrniwlQTVEALRDT 170
Cdd:COG2519  167 --------DMPDpweALEAVAKALKPGGVLVAyvptVNQVS----------KLVEALRES 208
PRK12335 PRK12335
tellurite resistance protein TehB; Provisional
 49-93 5.31e-04

tellurite resistance protein TehB; Provisional


Pssm-ID: 183450 [Multi-domain]  Cd Length: 287  Bit Score: 40.31  E-value: 5.31e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 578178742  49 VLDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLN 93
Cdd:PRK12335 124 ALDLGCGQGRNSLYLALLGFDVTAVDINQQSLENLQEIAEKENLN 168
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 39-146 5.56e-04

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 40.53  E-value: 5.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  39 ERLAAFPDAHVLDLGCGAGHASFTAAQQV--AQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGyaeSL--PFEDASFEA 114
Cdd:PRK09328 102 EALLLKEPLRVLDLGTGSGAIALALAKERpdAEVTAVDISPEALAVARRNAKHGLGARVEFLQG---DWfePLPGGRFDL 178

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 578178742 115 VISR--Y-SAHHWHDVGQ---------AL--------------REVKRVLKPGGIFII 146
Cdd:PRK09328 179 IVSNppYiPEADIHLLQPevrdhephlALfggedgldfyrriiEQAPRYLKPGGWLLL 236
MetW pfam07021
Methionine biosynthesis protein MetW; This family consists of several bacterial and one ...
 45-137 6.25e-04

Methionine biosynthesis protein MetW; This family consists of several bacterial and one archaeal methionine biosynthesis MetW proteins. Biosynthesis of methionine from homoserine in Pseudomonas putida takes place in three steps. The first step is the acylation of homoserine to yield an acyl-L-homoserine. This reaction is catalyzed by the products of the metXW genes and is equivalent to the first step in enterobacteria, gram-positive bacteria and fungi, except that in these microorganizms the reaction is catalyzed by a single polypeptide (the product of the metA gene in Escherichia coli and the met5 gene product in Neurospora crassa). In Pseudomonas putida, as in gram-positive bacteria and certain fungi, the second and third steps are a direct sulfhydrylation that converts the O-acyl-L-homoserine into homocysteine and further methylation to yield methionine. The latter reaction can be mediated by either of the two methionine synthetases present in the cells.


Pssm-ID: 399779  Cd Length: 193  Bit Score: 39.75  E-value: 6.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   45 PDAHVLDLGCGAGhASFTAAQQVAQVTAYDLSSQMLDVVaeAAKAKGLNNVttrQGYAES--LPFEDASFEAVISRYSAH 122
Cdd:pfam07021  13 PGSRVLDLGCGDG-TLLYLLKEEKGVDGYGIELDAAGVA--ECVAKGLYVI---QGDLDEglEHFPDKSFDYVILSQTLQ 86

                          90
                  ....*....|....*
gi 578178742  123 HWHDVGQALREVKRV 137
Cdd:pfam07021  87 ATRNPREVLDEMLRI 101
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 34-146 7.65e-04

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 40.13  E-value: 7.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  34 LVRLG-ERLAAFPDAHVLDLGCGAGHASFTAAQQV--AQVTAYDLSSQMLDVVAE-AAKAKGLNNVTTRQG-YAESLPfE 108
Cdd:COG2890  100 LVELAlALLPAGAPPRVLDLGTGSGAIALALAKERpdARVTAVDISPDALAVARRnAERLGLEDRVRFLQGdLFEPLP-G 178

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578178742 109 DASFEAVISR--Y-SAHHWHDVG---------QAL--------------REVKRVLKPGGIFII 146
Cdd:COG2890  179 DGRFDLIVSNppYiPEDEIALLPpevrdheprLALdggedgldfyrriiAQAPRLLKPGGWLLL 242
RsmB COG0144
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and ...
 41-143 1.23e-03

16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 439914 [Multi-domain]  Cd Length: 441  Bit Score: 39.61  E-value: 1.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  41 LAAFPDAHVLDLGCGAG----H-ASFTAAQqvAQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGYAESLP-FEDASFEA 114
Cdd:COG0144  245 LDPKPGERVLDLCAAPGgktlHlAELMGNK--GRVVAVDISEHRLKRLRENLARLGLSNVEVVVADARELLeWLPGKFDR 322

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 578178742 115 V-----------ISRysahH----WH----DVG-----QA--LREVKRVLKPGGI 143
Cdd:COG0144  323 VlldapcsgtgtLRR----HpdikWRrtpeDIAelaalQRelLDAAARLLKPGGR 373
metW TIGR02081
methionine biosynthesis protein MetW; This protein is found alongside MetX, of the enzyme that ...
 45-137 1.45e-03

methionine biosynthesis protein MetW; This protein is found alongside MetX, of the enzyme that acylates homoserine as a first step toward methionine biosynthesis, in many species. It appears to act in methionine biosynthesis but is not fully characterized. [Amino acid biosynthesis, Aspartate family]


Pssm-ID: 273958  Cd Length: 194  Bit Score: 38.50  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   45 PDAHVLDLGCGAGhASFTAAQQVAQVTAYDLSSQMLDVVaeAAKAKGLNNVttRQGYAESLP-FEDASFEAVISRYSAHH 123
Cdd:TIGR02081  13 PGSRVLDLGCGDG-ELLALLRDEKQVRGYGIEIDQDGVL--ACVARGVNVI--QGDLDEGLEaFPDKSFDYVILSQTLQA 87

                          90
                  ....*....|....
gi 578178742  124 WHDVGQALREVKRV 137
Cdd:TIGR02081  88 TRNPEEILDEMLRV 101
RlmK COG1092
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure ...
 40-145 1.54e-03

23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure and biogenesis]; 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 440709 [Multi-domain]  Cd Length: 392  Bit Score: 39.39  E-value: 1.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  40 RLAAF-PDAHVLDLGCGAGHASFTAAQQVA-QVTAYDLSSQMLDVVAEAAKAKGLN-NVTTRQG----YAESLPFEDASF 112
Cdd:COG1092  210 RVAELaKGKRVLNLFSYTGGFSVHAAAGGAkSVTSVDLSATALEWAKENAALNGLDdRHEFVQAdafdWLRELAREGERF 289

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 578178742 113 EAVI------SRySAHHWHDVGQA----LREVKRVLKPGGIFI 145
Cdd:COG1092  290 DLIIldppafAK-SKKDLFDAQRDykdlNRLALKLLAPGGILV 331
PLN02585 PLN02585
magnesium protoporphyrin IX methyltransferase
 49-114 2.11e-03

magnesium protoporphyrin IX methyltransferase


Pssm-ID: 215319 [Multi-domain]  Cd Length: 315  Bit Score: 38.68  E-value: 2.11e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578178742  49 VLDLGCGAGHASFTAAQQVAQVTAYDLSSQMldvVAEAAKakglnnvTTRQGYAESLPFEDASFEA 114
Cdd:PLN02585 148 VCDAGCGTGSLAIPLALEGAIVSASDISAAM---VAEAER-------RAKEALAALPPEVLPKFEA 203
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 39-153 2.18e-03

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 38.15  E-value: 2.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  39 ERLAAFPDAHVLDLGCGAGHAsfTA--AQQVAQVTAYDLSsqmlDVVAEAAKAK----GLNNVTTRQGY-AESLPfEDAS 111
Cdd:COG2518   60 EALDLKPGDRVLEIGTGSGYQ--AAvlARLAGRVYSVERD----PELAERARERlaalGYDNVTVRVGDgALGWP-EHAP 132

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 578178742 112 FEAVISRYSAhhwHDVGQALREvkrVLKPGGIfIIMDVMSPG 153
Cdd:COG2518  133 FDRIIVTAAA---PEVPEALLE---QLAPGGR-LVAPVGEGG 167
Rsm22 COG5459
Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) [Translation, ribosomal ...
 19-98 2.51e-03

Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) [Translation, ribosomal structure and biogenesis]; Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 444210 [Multi-domain]  Cd Length: 306  Bit Score: 38.40  E-value: 2.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  19 ASAYLSS-------AVHASgrdLVRLGERLAAFPDAHVLDLGCGAGHASFTAAQQ---VAQVTAYDLSSQMLDVVAEAAK 88
Cdd:COG5459   50 ALAYAAYrlpatyaAVRAA---LAELAEAGPDFAPLTVLDVGAGPGTAAWAAADAwpsLLDATLLERSAAALALGRRLAR 126

                         90
                 ....*....|
gi 578178742  89 AKGLNNVTTR 98
Cdd:COG5459  127 AAANPALETA 136
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
18-176 2.60e-03

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 38.12  E-value: 2.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   18 QASAYLSSA-VHASGRDLVRLGerlaafPDAHVLDLGCGAG-HASFTA--AQQVAQVTAYDLSSQMLDVVAEAAKAKGLN 93
Cdd:pfam01135  51 GYGQTISAPhMHAMMLELLELK------PGMRVLEIGSGSGyLTACFArmVGEVGRVVSIEHIPELVEIARRNLEKLGLE 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742   94 NVTT-----RQGYAESLPfedasfeavisrYSAHHwhdVGQALREVKRV----LKPGGIFIImdvmsPGHPVRNIWLQTV 164
Cdd:pfam01135 125 NVIVvvgdgRQGWPEFAP------------YDAIH---VGAAAPEIPEAlidqLKEGGRLVI-----PVGPNGNQVLQQF 184

                         170
                  ....*....|..
gi 578178742  165 EALRDTSHVQNY 176
Cdd:pfam01135 185 DKRNDGSVVIKD 196
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 48-153 4.34e-03

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 37.09  E-value: 4.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  48 HVLDLGCGAGHASF---TAAQQVAQVTAYDLSSQMLDVVAEAAKAKGL-NNVTTRQGYA-ESLP-FEDASFEAVI----- 116
Cdd:COG4122   19 RILEIGTGTGYSTLwlaRALPDDGRLTTIEIDPERAAIARENFARAGLaDRIRLILGDAlEVLPrLADGPFDLVFidadk 98

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 578178742 117 SRYSAHhwhdvgqaLREVKRVLKPGGIFIIMDVMSPG 153
Cdd:COG4122   99 SNYPDY--------LELALPLLRPGGLIVADNVLWHG 127
COG4798 COG4798
Predicted methyltransferase [General function prediction only];
86-148 6.30e-03

Predicted methyltransferase [General function prediction only];


Pssm-ID: 443826  Cd Length: 274  Bit Score: 37.20  E-value: 6.30e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578178742  86 AAKAKGLNNVTTRQGYAESLPFEDA-SFEAVISRYSAHHWHDVG---QALREVKRVLKPGGIFIIMD 148
Cdd:COG4798  121 AADPALYGNVRVTAFAPPDDPIAPPgSADLVLTFRNYHNWYRAGdaaAMFAAFFKALKPGGVLGVVD 187
Nnt1 COG3897
Protein N-terminal and lysine N-methylase, NNT1/EFM7 family [Posttranslational modification, ...
 44-174 6.43e-03

Protein N-terminal and lysine N-methylase, NNT1/EFM7 family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443104 [Multi-domain]  Cd Length: 216  Bit Score: 36.79  E-value: 6.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  44 FPDAHVLDLGCGAGHASFTAAQQ-VAQVTAYDLSSQMLDVVAEAAKAKGLnNVTTRQGYAESLPfEDASFEAVI-Srysa 121
Cdd:COG3897   69 VAGKRVLELGCGLGLVGIAAAKAgAADVTATDYDPEALAALRLNAALNGV-AITTRLGDWRDPP-AAGGFDLILgG---- 142

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742 122 hhwhDV-------GQALREVKRVLKPGGIFIIMDvmsPGHPVRNIWLQTVEALRDTSHVQ 174
Cdd:COG3897  143 ----DVlyerdlaEPLLPFLDRLAAPGGEVLIGD---PGRGYLPAFRERLEALAGYEVVT 195
PRK11207 PRK11207
tellurite resistance methyltransferase TehB;
49-110 6.47e-03

tellurite resistance methyltransferase TehB;


Pssm-ID: 183040  Cd Length: 197  Bit Score: 36.64  E-value: 6.47e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578178742  49 VLDLGCGAGHASFTAAQQVAQVTAYDLSSQMLDVVAEAAKAKGLNNVTTRQGYAESLPFEDA 110
Cdd:PRK11207  34 TLDLGCGNGRNSLYLAANGFDVTAWDKNPMSIANLERIKAAENLDNLHTAVVDLNNLTFDGE 95
PRK14967 PRK14967
putative methyltransferase; Provisional
 34-117 8.31e-03

putative methyltransferase; Provisional


Pssm-ID: 184931 [Multi-domain]  Cd Length: 223  Bit Score: 36.57  E-value: 8.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  34 LVRLGERLAAFPDAHVLDLGCGAGHASFTAAQQVA-QVTAYDLSSQMLDVVAEAAKAKGLnNVTTRQG-YAESLPFEdaS 111
Cdd:PRK14967  25 LADALAAEGLGPGRRVLDLCTGSGALAVAAAAAGAgSVTAVDISRRAVRSARLNALLAGV-DVDVRRGdWARAVEFR--P 101


                 ....*.
gi 578178742 112 FEAVIS 117
Cdd:PRK14967 102 FDVVVS 107
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
44-145 8.79e-03

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 36.67  E-value: 8.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578178742  44 FPDAHVLDLGCGAGHASFTAAQQ-VAQVTAYDLSSQMLDVVAEAAKakgLNNVTTrqgyAESLPFEDASFEAVIsrysah 122
Cdd:PRK00517 118 LPGKTVLDVGCGSGILAIAAAKLgAKKVLAVDIDPQAVEAARENAE---LNGVEL----NVYLPQGDLKADVIV------ 184

                         90       100       110
                 ....*....|....*....|....*....|...
gi 578178742 123 hwhdvgqA--LREV--------KRVLKPGGIFI 145
Cdd:PRK00517 185 -------AniLANPllelapdlARLLKPGGRLI 210
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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