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Conserved domains on  [gi|577038302|gb|EUC80591|]
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LPXTG cell wall anchor domain protein, partial [Streptococcus sp. SR1]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SHIRT pfam18655
SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.
 10-90 1.24e-27

SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.


:

Pssm-ID: 465830  Cd Length: 82  Bit Score: 102.85  E-value: 1.24e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577038302   10 THKATHEFVSGTPGKELPQEVKALLPADQTNLKDGSQATPTQPSQTEVKTSEGAWSFKSYDKTSETVNGSDVKFVGTWEF 89
Cdd:pfam18655   2 KYTVTYEFVSGTEGKELPQEVLDKLPADKTKVANGTKITLPKPEDDQVKVKDGTWKFSGWYLDEVTVNGADLKFTGTWTF 81


                  .
gi 577038302   90 T 90
Cdd:pfam18655  82 E 82
SHIRT pfam18655
SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.
 184-264 5.15e-27

SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.


:

Pssm-ID: 465830  Cd Length: 82  Bit Score: 101.31  E-value: 5.15e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577038302  184 THKAVHEFVSGTPGKELPQEVKALLPADQTDLKDGSQAIPTQPSQTEVKTAEGTWSFKSYDKTSETINGADAHFVGTWEF 263
Cdd:pfam18655   2 KYTVTYEFVSGTEGKELPQEVLDKLPADKTKVANGTKITLPKPEDDQVKVKDGTWKFSGWYLDEVTVNGADLKFTGTWTF 81


                  .
gi 577038302  264 T 264
Cdd:pfam18655  82 E 82
SHIRT pfam18655
SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.
 96-176 1.23e-26

SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.


:

Pssm-ID: 465830  Cd Length: 82  Bit Score: 100.15  E-value: 1.23e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577038302   96 THKAVHEFVSGTPGKELPQEVKALLPADQTNLKDGSQATPTQPSQTEVKTVEGTWSFKSYDKTSETINGSDVKFIGAWEF 175
Cdd:pfam18655   2 KYTVTYEFVSGTEGKELPQEVLDKLPADKTKVANGTKITLPKPEDDQVKVKDGTWKFSGWYLDEVTVNGADLKFTGTWTF 81


                  .
gi 577038302  176 T 176
Cdd:pfam18655  82 E 82
LPXTG_anchor TIGR01167
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region ...
 288-317 6.76e-06

LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other]


:

Pssm-ID: 273478 [Multi-domain]  Cd Length: 34  Bit Score: 42.08  E-value: 6.76e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 577038302  288 LPNTGSAVSGLLSIIGLAFASLAAFVLRKK 317
Cdd:TIGR01167   2 LPKTGESGNSLLLLLGLLLLGLGGLLLRKR 31
 
Name Accession Description Interval E-value
SHIRT pfam18655
SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.
 10-90 1.24e-27

SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.


Pssm-ID: 465830  Cd Length: 82  Bit Score: 102.85  E-value: 1.24e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577038302   10 THKATHEFVSGTPGKELPQEVKALLPADQTNLKDGSQATPTQPSQTEVKTSEGAWSFKSYDKTSETVNGSDVKFVGTWEF 89
Cdd:pfam18655   2 KYTVTYEFVSGTEGKELPQEVLDKLPADKTKVANGTKITLPKPEDDQVKVKDGTWKFSGWYLDEVTVNGADLKFTGTWTF 81


                  .
gi 577038302   90 T 90
Cdd:pfam18655  82 E 82
SHIRT pfam18655
SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.
 184-264 5.15e-27

SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.


Pssm-ID: 465830  Cd Length: 82  Bit Score: 101.31  E-value: 5.15e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577038302  184 THKAVHEFVSGTPGKELPQEVKALLPADQTDLKDGSQAIPTQPSQTEVKTAEGTWSFKSYDKTSETINGADAHFVGTWEF 263
Cdd:pfam18655   2 KYTVTYEFVSGTEGKELPQEVLDKLPADKTKVANGTKITLPKPEDDQVKVKDGTWKFSGWYLDEVTVNGADLKFTGTWTF 81


                  .
gi 577038302  264 T 264
Cdd:pfam18655  82 E 82
SHIRT pfam18655
SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.
 96-176 1.23e-26

SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.


Pssm-ID: 465830  Cd Length: 82  Bit Score: 100.15  E-value: 1.23e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577038302   96 THKAVHEFVSGTPGKELPQEVKALLPADQTNLKDGSQATPTQPSQTEVKTVEGTWSFKSYDKTSETINGSDVKFIGAWEF 175
Cdd:pfam18655   2 KYTVTYEFVSGTEGKELPQEVLDKLPADKTKVANGTKITLPKPEDDQVKVKDGTWKFSGWYLDEVTVNGADLKFTGTWTF 81


                  .
gi 577038302  176 T 176
Cdd:pfam18655  82 E 82
LPXTG_anchor TIGR01167
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region ...
 288-317 6.76e-06

LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other]


Pssm-ID: 273478 [Multi-domain]  Cd Length: 34  Bit Score: 42.08  E-value: 6.76e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 577038302  288 LPNTGSAVSGLLSIIGLAFASLAAFVLRKK 317
Cdd:TIGR01167   2 LPKTGESGNSLLLLLGLLLLGLGGLLLRKR 31
 
Name Accession Description Interval E-value
SHIRT pfam18655
SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.
 10-90 1.24e-27

SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.


Pssm-ID: 465830  Cd Length: 82  Bit Score: 102.85  E-value: 1.24e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577038302   10 THKATHEFVSGTPGKELPQEVKALLPADQTNLKDGSQATPTQPSQTEVKTSEGAWSFKSYDKTSETVNGSDVKFVGTWEF 89
Cdd:pfam18655   2 KYTVTYEFVSGTEGKELPQEVLDKLPADKTKVANGTKITLPKPEDDQVKVKDGTWKFSGWYLDEVTVNGADLKFTGTWTF 81


                  .
gi 577038302   90 T 90
Cdd:pfam18655  82 E 82
SHIRT pfam18655
SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.
 184-264 5.15e-27

SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.


Pssm-ID: 465830  Cd Length: 82  Bit Score: 101.31  E-value: 5.15e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577038302  184 THKAVHEFVSGTPGKELPQEVKALLPADQTDLKDGSQAIPTQPSQTEVKTAEGTWSFKSYDKTSETINGADAHFVGTWEF 263
Cdd:pfam18655   2 KYTVTYEFVSGTEGKELPQEVLDKLPADKTKVANGTKITLPKPEDDQVKVKDGTWKFSGWYLDEVTVNGADLKFTGTWTF 81


                  .
gi 577038302  264 T 264
Cdd:pfam18655  82 E 82
SHIRT pfam18655
SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.
 96-176 1.23e-26

SHIRT domain; The SHIRT domain is found in a range of presumed bacterial adhesin proteins.


Pssm-ID: 465830  Cd Length: 82  Bit Score: 100.15  E-value: 1.23e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577038302   96 THKAVHEFVSGTPGKELPQEVKALLPADQTNLKDGSQATPTQPSQTEVKTVEGTWSFKSYDKTSETINGSDVKFIGAWEF 175
Cdd:pfam18655   2 KYTVTYEFVSGTEGKELPQEVLDKLPADKTKVANGTKITLPKPEDDQVKVKDGTWKFSGWYLDEVTVNGADLKFTGTWTF 81


                  .
gi 577038302  176 T 176
Cdd:pfam18655  82 E 82
LPXTG_anchor TIGR01167
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region ...
 288-317 6.76e-06

LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other]


Pssm-ID: 273478 [Multi-domain]  Cd Length: 34  Bit Score: 42.08  E-value: 6.76e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 577038302  288 LPNTGSAVSGLLSIIGLAFASLAAFVLRKK 317
Cdd:TIGR01167   2 LPKTGESGNSLLLLLGLLLLGLGGLLLRKR 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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