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Conserved domains on  [gi|576077485|emb|CDL93555|]
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unnamed protein product [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SLC5-6-like_sbd super family cl00456
Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the ...
 6-381 6.96e-55

Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporters or solute sodium symporters), SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporters or Na+/Cl--dependent transporters), and nucleobase-cation-symport-1 (NCS1) transporters. SLC5s co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. SLC6s include Na+/Cl--dependent plasma membrane transporters for the monoamine neurotransmitters serotonin, dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. Members of this superfamily are important in human physiology and disease. They contain a functional core of 10 transmembrane helices (TMs): an inverted structural repeat, TMs1-5 and TMs6-10; TMs numbered to conform to the SLC6 Aquifex aeolicus LeuT.


The actual alignment was detected with superfamily member pfam01490:

Pssm-ID: 444915  Cd Length: 410  Bit Score: 197.14  E-value: 6.96e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485     6 ASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLAFHAYGKA 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLGYRLLGPK 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485    81 GKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGfqvGGTFRMFLLFAVSLCIVLPLSLQRNMMA-SIQS-FSAMAL 158
Cdd:pfam01490   83 GRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSS 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   159 LFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVV 237
Cdd:pfam01490  160 LYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIA 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   238 TTFYVMVGFFGYVSFTEATAGNVLMHFP-SNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLceqQQKDGTFAAGGYM 316
Cdd:pfam01490  240 TVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLL---FRKEAPFGASGKN 316

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 576077485   317 PP---LRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLW 381
Cdd:pfam01490  317 NPkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
 523-976 7.31e-08

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 56.92  E-value: 7.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  523 PSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQAleeagdlpedPQKVPEADGQPAVQPAKEdlgpgdrg 602
Cdd:PRK07764  381 LERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPA----------PAAAPQPAPAPAPAPAPP-------- 442

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  603 lhPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPgPGLPPEPREQRDVERAGgNQ 682
Cdd:PRK07764  443 --SPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAA-PAAPAGADDAATLRERW-PE 518

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  683 AASQLEEAGR---AEMLDHAVLLQVIKEQQV-------QQKRLLDQQ--EKLLAVIeeqHKEIHQQRQEDeedkprqVEV 750
Cdd:PRK07764  519 ILAAVPKRSRktwAILLPEATVLGVRGDTLVlgfstggLARRFASPGnaEVLVTAL---AEELGGDWQVE-------AVV 588

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  751 HQEPGAAVPRGQEAPEGKARETvenlpPLPLDPVLRAPGGRPAPSQDlnQRSLEHSEGPVGRDPAGPPdgGPDTEPRAAQ 830
Cdd:PRK07764  589 GPAPGAAGGEGPPAPASSGPPE-----EAARPAAPAAPAAPAAPAPA--GAAAAPAEASAAPAPGVAA--PEHHPKHVAV 659

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  831 AKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERlaeefPGQSQDVTGGSQDRKKPGKEVAATGTSILKEA 910
Cdd:PRK07764  660 PDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA-----PAPAATPPAGQADDPAAQPPQAAQGASAPSPA 734

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 576077485  911 NWlVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHR 976
Cdd:PRK07764  735 AD-DPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR 799
 
Name Accession Description Interval E-value
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
 6-381 6.96e-55

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 197.14  E-value: 6.96e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485     6 ASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLAFHAYGKA 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLGYRLLGPK 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485    81 GKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGfqvGGTFRMFLLFAVSLCIVLPLSLQRNMMA-SIQS-FSAMAL 158
Cdd:pfam01490   83 GRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSS 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   159 LFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVV 237
Cdd:pfam01490  160 LYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIA 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   238 TTFYVMVGFFGYVSFTEATAGNVLMHFP-SNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLceqQQKDGTFAAGGYM 316
Cdd:pfam01490  240 TVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLL---FRKEAPFGASGKN 316

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 576077485   317 PP---LRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLW 381
Cdd:pfam01490  317 NPkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00206 PTZ00206
amino acid transporter; Provisional
 14-366 1.09e-25

amino acid transporter; Provisional


Pssm-ID: 240313  Cd Length: 467  Bit Score: 111.88  E-value: 1.09e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   14 NIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLM 93
Cdd:PTZ00206   68 NIASSTVGAGIVGLPSAANSSGLVMAMIYLIIITAMTIFSIYALGVAADKTNIRTYEGVARVLLGPWGSYYVAATRAFHG 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   94 LGTCIAFYVVIGDL------GSNffARLFGFQVGGTfrMFLLFAVSLCIVLPLSLQRNmMASIQSFSAMALLFYTVFMFV 167
Cdd:PTZ00206  148 FSACVAYVISVGDIlsatlkGTN--APDFLKQKSGN--RLLTSLMWLCFMLPLVIPRH-IDSLRYVSTIAVSFMVYLVIV 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  168 IVLSSLKHGLfsGQWLRRVSY--------VRWEGVFRCIP---IFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNV 236
Cdd:PTZ00206  223 IVVHSCMNGL--PENIKNVSVgkddnaeiILFNSGNRAIEglgVFIFAYVFQITAYEVYMDMTNRSVGKFVLASTIAMGM 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  237 VTTFYVMVGFFGYVSFTEATAGNVLMHF-PSNLVTEMLR-VGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGg 314
Cdd:PTZ00206  301 CFTMYVLTAFFGYMDFGRNVTGSVLLMYdPVNEPAIMVGfVGVLVKLFVSYALLGMACRNALYDVIGWDARKVAFWKHC- 379

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 576077485  315 ympplrFKALTLSVVFgtMVGGILIPNVETILGLTGATMGSLICFICPALIY 366
Cdd:PTZ00206  380 ------IAVVTLSVVM--LLCGLFIPKINTVLGFAGSISGGLLGFILPALLF 423
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 523-976 7.31e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 56.92  E-value: 7.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  523 PSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQAleeagdlpedPQKVPEADGQPAVQPAKEdlgpgdrg 602
Cdd:PRK07764  381 LERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPA----------PAAAPQPAPAPAPAPAPP-------- 442

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  603 lhPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPgPGLPPEPREQRDVERAGgNQ 682
Cdd:PRK07764  443 --SPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAA-PAAPAGADDAATLRERW-PE 518

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  683 AASQLEEAGR---AEMLDHAVLLQVIKEQQV-------QQKRLLDQQ--EKLLAVIeeqHKEIHQQRQEDeedkprqVEV 750
Cdd:PRK07764  519 ILAAVPKRSRktwAILLPEATVLGVRGDTLVlgfstggLARRFASPGnaEVLVTAL---AEELGGDWQVE-------AVV 588

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  751 HQEPGAAVPRGQEAPEGKARETvenlpPLPLDPVLRAPGGRPAPSQDlnQRSLEHSEGPVGRDPAGPPdgGPDTEPRAAQ 830
Cdd:PRK07764  589 GPAPGAAGGEGPPAPASSGPPE-----EAARPAAPAAPAAPAAPAPA--GAAAAPAEASAAPAPGVAA--PEHHPKHVAV 659

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  831 AKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERlaeefPGQSQDVTGGSQDRKKPGKEVAATGTSILKEA 910
Cdd:PRK07764  660 PDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA-----PAPAATPPAGQADDPAAQPPQAAQGASAPSPA 734

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 576077485  911 NWlVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHR 976
Cdd:PRK07764  735 AD-DPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR 799
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 399-708 1.24e-03

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 42.74  E-value: 1.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  399 EEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQD---------PVVAVAEDGREKPKL-PKEREELEQAQIKGPVDVPGR 468
Cdd:COG5180   160 PILAKDPDGDSASTLPPPAEKLDKVLTEPRDALKdspekldrpKVEVKDEAQEEPPDLtGGADHPRPEAASSPKVDPPST 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  469 EDGKEAPeeaqLDRPGQGIAVPVGEAHRHEPPVPHDKvvvDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSERE 548
Cdd:COG5180   240 SEARSRP----ATVDAQPEMRPPADAKERRRAAIGDT---PAAEPPGLPVLEAGSEPQSDAPEAETARPIDVKGVASAPP 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  549 KQEPEQGEVGKRPGQAQALEEAGdlpEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKG 628
Cdd:COG5180   313 ATRPVRPPGGARDPGTPRPGQPT---ERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNG 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  629 GPPPGN---AAGDTGQPAEDS---DHGGKPPLPAE------------KPAPGPGLPPEPREQRDVERAGGNQAASQLEEA 690
Cdd:COG5180   390 APQPGLgrrGAPGPPMGAGDLvqaALDGGGRETASlggaaggagqgpKADFVPGDAESVSGPAGLADQAGAAASTAMADF 469

                         330       340
                  ....*....|....*....|..
gi 576077485  691 GR----AEMLDHAVLLQVIKEQ 708
Cdd:COG5180   470 VApvtdATPVDVADVLGVRPDA 491
DUF4670 pfam15709
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...
 552-753 4.51e-03

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.


Pssm-ID: 464815 [Multi-domain]  Cd Length: 522  Bit Score: 41.09  E-value: 4.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   552 PEQGEVGKRPGQAQAleeagdlpedpqkvpeADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKakgGPP 631
Cdd:pfam15709  193 PKREREGKVHGEAEA----------------AVGKSRESKAEKKSELISKGKKTGAKRKRTQKERNLEVAAELS---GPD 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   632 PGNAAGDTGQPAE---DSDHGGKPPLPAEK--------------------PAPGPGLPPEPREQRD-----VERAGGNQA 683
Cdd:pfam15709  254 VINSKETEDASERgafSSDSVVEDPWLSSKydaeesqvsidgrssptqtfVVTGNMESEEERSEEDpskalLEKREQEKA 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   684 ASQLEEAGRAEMLdhavLLQV---IKEQQVQQKRLLDQQEKLLAVIEE----------------QHKEIHQQRQEDEEDK 744
Cdd:pfam15709  334 SRDRLRAERAEMR----RLEVerkRREQEEQRRLQQEQLERAEKMREEleleqqrrfeeirlrkQRLEEERQRQEEEERK 409

                          250
                   ....*....|
gi 576077485   745 PR-QVEVHQE 753
Cdd:pfam15709  410 QRlQLQAAQE 419
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 505-773 6.97e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 40.75  E-value: 6.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   505 KVVVDEGQDR--EVPEENKPPSRhAGGKAPGVQGQMAPPLPDSEREKQEPEQGEV-----GKRPGQAQALEEAGDLPEDP 577
Cdd:TIGR00927  632 KGDVAEAEHTgeRTGEEGERPTE-AEGENGEESGGEAEQEGETETKGENESEGEIpaerkGEQEGEGEIEAKEADHKGET 710

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   578 QKVPEADGQPAVQPAKEDLGPGDRGlhPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDH------GGK 651
Cdd:TIGR00927  711 EAEEVEHEGETEAEGTEDEGEIETG--EEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDegeiqaGED 788

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   652 PPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHK 731
Cdd:TIGR00927  789 GEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDGGDSEEEEE 868

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 576077485   732 EihqQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETV 773
Cdd:TIGR00927  869 E---EEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQAI 907
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 532-680 8.50e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 39.75  E-value: 8.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  532 PGVQGQMAPPLPDSEREKQEPEQG--EVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQA 609
Cdd:NF040712  170 PGAHGGTVTALDDEARWLIDPDFGrpLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRR 249

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 576077485  610 VLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPG-PGLPPEPREQRDVERAGG 680
Cdd:NF040712  250 AGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPaAPAAPEAEEPARPEPPPA 321
 
Name Accession Description Interval E-value
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
 6-381 6.96e-55

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 197.14  E-value: 6.96e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485     6 ASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLAFHAYGKA 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLGYRLLGPK 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485    81 GKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGfqvGGTFRMFLLFAVSLCIVLPLSLQRNMMA-SIQS-FSAMAL 158
Cdd:pfam01490   83 GRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSS 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   159 LFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVV 237
Cdd:pfam01490  160 LYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIA 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   238 TTFYVMVGFFGYVSFTEATAGNVLMHFP-SNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLceqQQKDGTFAAGGYM 316
Cdd:pfam01490  240 TVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLL---FRKEAPFGASGKN 316

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 576077485   317 PP---LRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLW 381
Cdd:pfam01490  317 NPkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00206 PTZ00206
amino acid transporter; Provisional
 14-366 1.09e-25

amino acid transporter; Provisional


Pssm-ID: 240313  Cd Length: 467  Bit Score: 111.88  E-value: 1.09e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   14 NIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLM 93
Cdd:PTZ00206   68 NIASSTVGAGIVGLPSAANSSGLVMAMIYLIIITAMTIFSIYALGVAADKTNIRTYEGVARVLLGPWGSYYVAATRAFHG 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   94 LGTCIAFYVVIGDL------GSNffARLFGFQVGGTfrMFLLFAVSLCIVLPLSLQRNmMASIQSFSAMALLFYTVFMFV 167
Cdd:PTZ00206  148 FSACVAYVISVGDIlsatlkGTN--APDFLKQKSGN--RLLTSLMWLCFMLPLVIPRH-IDSLRYVSTIAVSFMVYLVIV 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  168 IVLSSLKHGLfsGQWLRRVSY--------VRWEGVFRCIP---IFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNV 236
Cdd:PTZ00206  223 IVVHSCMNGL--PENIKNVSVgkddnaeiILFNSGNRAIEglgVFIFAYVFQITAYEVYMDMTNRSVGKFVLASTIAMGM 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  237 VTTFYVMVGFFGYVSFTEATAGNVLMHF-PSNLVTEMLR-VGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGg 314
Cdd:PTZ00206  301 CFTMYVLTAFFGYMDFGRNVTGSVLLMYdPVNEPAIMVGfVGVLVKLFVSYALLGMACRNALYDVIGWDARKVAFWKHC- 379

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 576077485  315 ympplrFKALTLSVVFgtMVGGILIPNVETILGLTGATMGSLICFICPALIY 366
Cdd:PTZ00206  380 ------IAVVTLSVVM--LLCGLFIPKINTVLGFAGSISGGLLGFILPALLF 423
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 523-976 7.31e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 56.92  E-value: 7.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  523 PSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQAleeagdlpedPQKVPEADGQPAVQPAKEdlgpgdrg 602
Cdd:PRK07764  381 LERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPA----------PAAAPQPAPAPAPAPAPP-------- 442

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  603 lhPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPgPGLPPEPREQRDVERAGgNQ 682
Cdd:PRK07764  443 --SPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAA-PAAPAGADDAATLRERW-PE 518

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  683 AASQLEEAGR---AEMLDHAVLLQVIKEQQV-------QQKRLLDQQ--EKLLAVIeeqHKEIHQQRQEDeedkprqVEV 750
Cdd:PRK07764  519 ILAAVPKRSRktwAILLPEATVLGVRGDTLVlgfstggLARRFASPGnaEVLVTAL---AEELGGDWQVE-------AVV 588

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  751 HQEPGAAVPRGQEAPEGKARETvenlpPLPLDPVLRAPGGRPAPSQDlnQRSLEHSEGPVGRDPAGPPdgGPDTEPRAAQ 830
Cdd:PRK07764  589 GPAPGAAGGEGPPAPASSGPPE-----EAARPAAPAAPAAPAAPAPA--GAAAAPAEASAAPAPGVAA--PEHHPKHVAV 659

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  831 AKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERlaeefPGQSQDVTGGSQDRKKPGKEVAATGTSILKEA 910
Cdd:PRK07764  660 PDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA-----PAPAATPPAGQADDPAAQPPQAAQGASAPSPA 734

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 576077485  911 NWlVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHR 976
Cdd:PRK07764  735 AD-DPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR 799
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 517-699 6.40e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 50.37  E-value: 6.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  517 PEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPA-VQPAKED 595
Cdd:PRK07764  606 SGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAApAAPPPAP 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  596 LGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDV 675
Cdd:PRK07764  686 APAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPA 765

                         170       180
                  ....*....|....*....|....
gi 576077485  676 ERAGGNQAASQLEEAGRAEMLDHA 699
Cdd:PRK07764  766 PAAAPAAAPPPSPPSEEEEMAEDD 789
PHA03247 PHA03247
large tegument protein UL36; Provisional
 448-930 2.41e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 2.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  448 PKEREELEQAQIKGPvDVPGREDGKEAPEEAQLDRPGQGIAVPVgeahrhePPVPHdkvvvdegqdrevPEENKPPSRHA 527
Cdd:PHA03247 2575 PRPSEPAVTSRARRP-DAPPQSARPRAPVDDRGDPRGPAPPSPL-------PPDTH-------------APDPPPPSPSP 2633

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  528 GGKAPGVQGQMAPPLPdsEREKQEPEQGEVgKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQP--AKEDLGPGDRGLHP 605
Cdd:PHA03247 2634 AANEPDPHPPPTVPPP--ERPRDDPAPGRV-SRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltSLADPPPPPPTPEP 2710

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  606 RPQAVLSEQQNGLAVGGGEKAKGGPP----PGNAAGDTGQPAEDSdHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGN 681
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPALPaapaPPAVPAGPATPGGPA-RPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVA 2789

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  682 QAASQLEEAGRAEmldhavllqvikeqqvqqkrlldqqekllavieeqhkeihqqrqeDEEDKPRQV--EVHQEPGAAVP 759
Cdd:PHA03247 2790 SLSESRESLPSPW---------------------------------------------DPADPPAAVlaPAAALPPAASP 2824

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  760 RGQEAPEGKARETVENLPPLPLDPVLrAPGGRPAPSQDLNQRSlehsegpvgrdPAGPPDGGPDTEPRAAQAKLrdgQKD 839
Cdd:PHA03247 2825 AGPLPPPTSAQPTAPPPPPGPPPPSL-PLGGSVAPGGDVRRRP-----------PSRSPAAKPAAPARPPVRRL---ARP 2889

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  840 AAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVAATG-TSILKEANWLVAGPG 918
Cdd:PHA03247 2890 AVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGePSGAVPQPWLGALVP 2969

                         490
                  ....*....|..
gi 576077485  919 AETGDPRMKPKQ 930
Cdd:PHA03247 2970 GRVAVPRFRVPQ 2981
PHA03169 PHA03169
hypothetical protein; Provisional
 448-670 1.50e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 45.73  E-value: 1.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  448 PKEREELEQAQIKGPVDVPGREDGKEAPEEaqldRPGQGIAVPVGE--AHRHEPPVPHDKVVVDEGQDREVPEENKP--P 523
Cdd:PHA03169   56 PQVRAVAEQGHRQTESDTETAEESRHGEKE----ERGQGGPSGSGSesVGSPTPSPSGSAEELASGLSPENTSGSSPesP 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  524 SRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQaqalEEAGDLPEDPQKVPEADGQPAVQ-PAKEDLGP-GDR 601
Cdd:PHA03169  132 ASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSH----EDSPEEPEPPTSEPEPDSPGPPQsETPTSSPPpQSP 207

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 576077485  602 GLHPRPQavlseqqnglavgGGEKAKGGPPPgnaagDTGQPAEDSDHggkpplPAEKPAPGPGlPPEPR 670
Cdd:PHA03169  208 PDEPGEP-------------QSPTPQQAPSP-----NTQQAVEHEDE------PTEPEREGPP-FPGHR 251
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
756-966 1.58e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.00  E-value: 1.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  756 AAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPsQDLNQRSLEHSEGPVGRdPAGPPDGGPDTEPRAAQAKLrd 835
Cdd:PRK07003  374 ARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAP-KAAAAAAATRAEAPPAA-PAPPATADRGDDAADGDAPV-- 449

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  836 gQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAeefpgqsqdvtggsqdRKKPGKEVAATGTSILKEANWLVA 915
Cdd:PRK07003  450 -PAKANARASADSRCDERDAQPPADSGSASAPASDAPPDA----------------AFEPAPRAAAPSAATPAAVPDARA 512

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 576077485  916 GPGAETGD---PRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISD 966
Cdd:PRK07003  513 PAAASREDapaAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSD 566
PHA03247 PHA03247
large tegument protein UL36; Provisional
 517-905 2.03e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 2.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  517 PEENKPPSRHAGGKAPGVQGQ---MAPPLPDSEREKQEPEQgevgkRPGQA---------QALEE-----AGD----LPE 575
Cdd:PHA03247 2483 PAEARFPFAAGAAPDPGGGGPpdpDAPPAPSRLAPAILPDE-----PVGEPvhprmltwiRGLEElasddAGDppppLPP 2557

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  576 DPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAvlSEQQNGLAVGGGEKakgGPPPGNAAGDTGQPAedsDHGGKPPLP 655
Cdd:PHA03247 2558 AAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDA--PPQSARPRAPVDDR---GDPRGPAPPSPLPPD---THAPDPPPP 2629

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  656 AEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAVllQVIKEQQVQQKRLLDQQEKLLAVIEEQHKeihQ 735
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAA--QASSPPQRPRRRAARPTVGSLTSLADPPP---P 2704

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  736 QRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPSQdlnqrslehseGPVGRDPA 815
Cdd:PHA03247 2705 PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAG-----------PPAPAPPA 2773

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  816 GPPDGGPDTEPRAAQAKLRDGQKDA--------------APRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQ 881
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpspwdpadppaavlAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         410       420
                  ....*....|....*....|....
gi 576077485  882 SQDVTGGSQDRKKPGKEVAATGTS 905
Cdd:PHA03247 2854 GSVAPGGDVRRRPPSRSPAAKPAA 2877
PHA03169 PHA03169
hypothetical protein; Provisional
 502-676 5.41e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 43.81  E-value: 5.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  502 PHDKVVVDEGQDR-EVPEENKPPSRHAGGKAPGVQGqmapPLPDSEREKQEPEQGEVGKRPGQAQALE--------EAGD 572
Cdd:PHA03169   56 PQVRAVAEQGHRQtESDTETAEESRHGEKEERGQGG----PSGSGSESVGSPTPSPSGSAEELASGLSpentsgssPESP 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  573 LPEDPQKVPEADGQPAVQPAKEDLGP-----GDRGLHPRPQAVLSEqqnglavggGEKAKGGPPPGNAAGDTGQPAEDSD 647
Cdd:PHA03169  132 ASHSPPPSPPSHPGPHEPAPPESHNPspnqqPSSFLQPSHEDSPEE---------PEPPTSEPEPDSPGPPQSETPTSSP 202

                         170       180       190
                  ....*....|....*....|....*....|
gi 576077485  648 HGGKPP-LPAEKPAPGPGLPPEPREQRDVE 676
Cdd:PHA03169  203 PPQSPPdEPGEPQSPTPQQAPSPNTQQAVE 232
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 396-694 7.46e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 7.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  396 SVSEEVPEDLAEEAPG---GRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGK 472
Cdd:PHA03307   26 ATPGDAADDLLSGSQGqlvSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGS 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  473 EAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQ-GQMAPPLPDSEREKQE 551
Cdd:PHA03307  106 PTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASsRQAALPLSSPEETARA 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  552 PEQGEVGKRPGQAQALEEAGDLPEDPqkvPEADGQPAVQPAkeDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPP 631
Cdd:PHA03307  186 PSSPPAEPPPSTPPAAASPRPPRRSS---PISASASSPAPA--PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRP 260

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 576077485  632 PGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAE 694
Cdd:PHA03307  261 APITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRE 323
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 471-873 7.85e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 7.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  471 GKEAPEEAQLDRPGQgiaVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQ 550
Cdd:PHA03307   28 PGDAADDLLSGSQGQ---LVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREG 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  551 EPEQGEVGKRPGQAQALEEAG-------DLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSeqqNGLAVGGG 623
Cdd:PHA03307  105 SPTPPGPSSPDPPPPTPPPASpppspapDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAA---LPLSSPEE 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  624 EKAKGGPPPGNAAGDTGQP-AEDSDHGGKPPLPAEKPAPGPGLPPEPReqRDVERAGGNQAASQLEEAGRAemldhavll 702
Cdd:PHA03307  182 TARAPSSPPAEPPPSTPPAaASPRPPRRSSPISASASSPAPAPGRSAA--DDAGASSSDSSSSESSGCGWG--------- 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  703 qvikeqqvqqkrlldqqekllavieeqhkeihqQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLD 782
Cdd:PHA03307  251 ---------------------------------PENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPS 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  783 PVLRAPGGRPAPSQ--DLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKElpKGPEQVPV 860
Cdd:PHA03307  298 PSPSSPGSGPAPSSprASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRK--RPRPSRAP 375

                         410
                  ....*....|...
gi 576077485  861 PDPAREAGGPEER 873
Cdd:PHA03307  376 SSPAASAGRPTRR 388
PHA03321 PHA03321
tegument protein VP11/12; Provisional
 468-669 9.25e-04

tegument protein VP11/12; Provisional


Pssm-ID: 223041 [Multi-domain]  Cd Length: 694  Bit Score: 43.41  E-value: 9.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  468 REDgkEAPEEAQLDRPGQGIAVPVgEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQM---APPLPD 544
Cdd:PHA03321  437 RRD--NDPPPPPRARPGSTPACAR-RARAQRARDAGPEYVDPLGALRRLPAGAAPPPEPAAAPSPATYYTRmggGPPRLP 513

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  545 SeREKQEPEQgevgkRPGQAQALEEAGDLPEDPQKVPEADGQPAvqpakEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGE 624
Cdd:PHA03321  514 P-RNRATETL-----RPDWGPPAAAPPEQMEDPYLEPDDDRFDR-----RDGAAAAATSHPREAPAPDDDPIYEGVSDSE 582

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 576077485  625 ---------------------KAKGGPPPGNAAGDTGQPAEDSDHG------GKPPLPAEKPAPGPGLPPEP 669
Cdd:PHA03321  583 epvyeeiptprvyqnplprpmEGAGEPPDLDAPTSPWVEEENPIYGwgdsplFSPPPAARFPPPDPALSPEP 654
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 399-708 1.24e-03

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 42.74  E-value: 1.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  399 EEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQD---------PVVAVAEDGREKPKL-PKEREELEQAQIKGPVDVPGR 468
Cdd:COG5180   160 PILAKDPDGDSASTLPPPAEKLDKVLTEPRDALKdspekldrpKVEVKDEAQEEPPDLtGGADHPRPEAASSPKVDPPST 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  469 EDGKEAPeeaqLDRPGQGIAVPVGEAHRHEPPVPHDKvvvDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSERE 548
Cdd:COG5180   240 SEARSRP----ATVDAQPEMRPPADAKERRRAAIGDT---PAAEPPGLPVLEAGSEPQSDAPEAETARPIDVKGVASAPP 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  549 KQEPEQGEVGKRPGQAQALEEAGdlpEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKG 628
Cdd:COG5180   313 ATRPVRPPGGARDPGTPRPGQPT---ERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNG 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  629 GPPPGN---AAGDTGQPAEDS---DHGGKPPLPAE------------KPAPGPGLPPEPREQRDVERAGGNQAASQLEEA 690
Cdd:COG5180   390 APQPGLgrrGAPGPPMGAGDLvqaALDGGGRETASlggaaggagqgpKADFVPGDAESVSGPAGLADQAGAAASTAMADF 469

                         330       340
                  ....*....|....*....|..
gi 576077485  691 GR----AEMLDHAVLLQVIKEQ 708
Cdd:COG5180   470 VApvtdATPVDVADVLGVRPDA 491
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 619-878 1.38e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 1.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  619 AVGGGEkAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGlpPEPREQRDVERAGGNQAASQLEEAGRAEMLDH 698
Cdd:PRK07764  586 AVVGPA-PGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPA--GAAAAPAEASAAPAPGVAAPEHHPKHVAVPDA 662

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  699 AvllqvikeqqvqqkrlldqqekllAVIEEQHKEIHQQRQEDEEdkPRQVEVHQEPGAAVPRGQEAPEGKAREtvenlpp 778
Cdd:PRK07764  663 S------------------------DGGDGWPAKAGGAAPAAPP--PAPAPAAPAAPAGAAPAQPAPAPAATP------- 709

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  779 lpldpvlrAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKELP---KGP 855
Cdd:PRK07764  710 --------PAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPpspPSE 781

                         250       260
                  ....*....|....*....|...
gi 576077485  856 EQVPVPDPAREAGGPEERLAEEF 878
Cdd:PRK07764  782 EEEMAEDDAPSMDDEDRRDAEEV 804
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 487-695 3.59e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 3.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  487 IAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPG----VQGQMAPPLPDSEREKQEPEQGEVGKRP- 561
Cdd:PRK07764  588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAapaeASAAPAPGVAAPEHHPKHVAVPDASDGGd 667

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  562 GQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGG-----PPPGNAA 636
Cdd:PRK07764  668 GWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAAddpvpLPPEPDD 747

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 576077485  637 GDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEM 695
Cdd:PRK07764  748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVAM 806
rne PRK10811
ribonuclease E; Reviewed
 537-748 3.74e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.56  E-value: 3.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  537 QMAPPLPDSEREKQEPEQgevgkrPGQAqaleeAGDLPEDPQKVPEAdgQPAVQPAKEDlgpgdrglhPRPQAVLSEQQN 616
Cdd:PRK10811  509 AMALPSEEEFAERKRPEQ------PALA-----TFAMPDVPPAPTPA--EPAAPVVAAA---------PKAAAATPPAQP 566

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  617 GL----------AVGGGEKAKGGPPPGNAAGDTGQPAEDS---------DHGGKPPLPAEKPAPgpglppEPREQRDVER 677
Cdd:PRK10811  567 GLlsrffgalkaLFSGGEETKPQEQPAPKAEAKPERQQDRrkprqnnrrDRNERRDTRDNRTRR------EGRENREENR 640

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  678 AGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQ-----------KRLLDQQEKLLAVIEEQHKEihqqrqEDEEDKPR 746
Cdd:PRK10811  641 RNRRQAQQQTAETRESQQAEVTEKARTQDEQQQAPrrerqrrrndeKRQAQQEAKALNVEEQSVQE------TEQEERVQ 714


                  ..
gi 576077485  747 QV 748
Cdd:PRK10811  715 QV 716
dnaA PRK14086
chromosomal replication initiator protein DnaA;
539-682 4.05e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 41.35  E-value: 4.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  539 APPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPqkvPEADGQPAVQPAKEDLGPGDR-GLHPRPQAVLSEQQNG 617
Cdd:PRK14086   95 PAPPPPHARRTSEPELPRPGRRPYEGYGGPRADDRPPGL---PRQDQLPTARPAYPAYQQRPEpGAWPRAADDYGWQQQR 171

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 576077485  618 LavgggekakgGPPPGNaagDTGQPAEDSdhggkPPLPAEKPAPGPGLPPEPREQRDVERAGGNQ 682
Cdd:PRK14086  172 L----------GFPPRA---PYASPASYA-----PEQERDREPYDAGRPEYDQRRRDYDHPRPDW 218
PHA03247 PHA03247
large tegument protein UL36; Provisional
 433-663 4.18e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 4.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  433 PVVAVAEDGREKPKLPKEREELEQaqikgPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKV---VVD 509
Cdd:PHA03247 2784 TRPAVASLSESRESLPSPWDPADP-----PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggsVAP 2858

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  510 EGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEvgKRPGQAQAleeagdlPEDPQKVPEADGQPAV 589
Cdd:PHA03247 2859 GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQP--ERPPQPQA-------PPPPQPQPQPPPPPQP 2929

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 576077485  590 QPAKEDlgpgdrglHPRPQAVLSEQQNglAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGP 663
Cdd:PHA03247 2930 QPPPPP--------PPRPQPPLAPTTD--PAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASST 2993
DUF4670 pfam15709
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...
 552-753 4.51e-03

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.


Pssm-ID: 464815 [Multi-domain]  Cd Length: 522  Bit Score: 41.09  E-value: 4.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   552 PEQGEVGKRPGQAQAleeagdlpedpqkvpeADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKakgGPP 631
Cdd:pfam15709  193 PKREREGKVHGEAEA----------------AVGKSRESKAEKKSELISKGKKTGAKRKRTQKERNLEVAAELS---GPD 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   632 PGNAAGDTGQPAE---DSDHGGKPPLPAEK--------------------PAPGPGLPPEPREQRD-----VERAGGNQA 683
Cdd:pfam15709  254 VINSKETEDASERgafSSDSVVEDPWLSSKydaeesqvsidgrssptqtfVVTGNMESEEERSEEDpskalLEKREQEKA 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   684 ASQLEEAGRAEMLdhavLLQV---IKEQQVQQKRLLDQQEKLLAVIEE----------------QHKEIHQQRQEDEEDK 744
Cdd:pfam15709  334 SRDRLRAERAEMR----RLEVerkRREQEEQRRLQQEQLERAEKMREEleleqqrrfeeirlrkQRLEEERQRQEEEERK 409

                          250
                   ....*....|
gi 576077485   745 PR-QVEVHQE 753
Cdd:pfam15709  410 QRlQLQAAQE 419
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
523-684 4.55e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.99  E-value: 4.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  523 PSRHAGGKAPGVQGQMAPPLPDSEREKQE---PEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPG 599
Cdd:PRK07003  385 ARAAAAVGASAVPAVTAVTGAAGAALAPKaaaAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCD 464

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  600 DRGLHPRPQAVLSEQQNGLAVGGGEKAKgGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLP----PEPREQRDV 675
Cdd:PRK07003  465 ERDAQPPADSGSASAPASDAPPDAAFEP-APRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPearpPTPAAAAPA 543


                  ....*....
gi 576077485  676 ERAGGNQAA 684
Cdd:PRK07003  544 ARAGGAAAA 552
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 432-874 6.05e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.84  E-value: 6.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  432 DPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGE---AHRHEPPVPHDKVVV 508
Cdd:PRK10263  370 EPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQpyyAPAPEQPVAGNAWQA 449

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  509 DEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPlPDSEREKQEPEQGEVGKRPGQAQA--LEEAGDLPEDPQKVPEADGQ 586
Cdd:PRK10263  450 EEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQ-PVEQQPVVEPEPVVEETKPARPPLyyFEEVEEKRAREREQLAAWYQ 528

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  587 PAVQPAKEDLgPGDRGLHPRPQAVLSEQQNGLAVGG-GEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPlPAEKPAPGPGL 665
Cdd:PRK10263  529 PIPEPVKEPE-PIKSSLKAPSVAAVPPVEAAAAVSPlASGVKKATLATGAAATVAAPVFSLANSGGPR-PQVKEGIGPQL 606

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  666 PPEPR----EQRDVERAGGNQAASQL--EEAGRAEMLDHAVLLQVIKE-----QQVQQKRLLDQQEKLLAVIEEQHKEIH 734
Cdd:PRK10263  607 PRPKRirvpTRRELASYGIKLPSQRAaeEKAREAQRNQYDSGDQYNDDeidamQQDELARQFAQTQQQRYGEQYQHDVPV 686

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  735 QQRQED---EEDKPRQVEVHQE-------PGAAVPRGQEAPE-GKARETVENLPPLPLDPVLRAPGGRPApSQDLNQRSL 803
Cdd:PRK10263  687 NAEDADaaaEAELARQFAQTQQqrysgeqPAGANPFSLDDFEfSPMKALLDDGPHEPLFTPIVEPVQQPQ-QPVAPQQQY 765

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  804 EHSEGPVG--------RDPAGPP-DGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKELPKGPE---QVPVPDPAREaggPE 871
Cdd:PRK10263  766 QQPQQPVApqpqyqqpQQPVAPQpQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQpqyQQPQQPVAPQ---PQ 842


                  ...
gi 576077485  872 ERL 874
Cdd:PRK10263  843 DTL 845
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 505-773 6.97e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 40.75  E-value: 6.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   505 KVVVDEGQDR--EVPEENKPPSRhAGGKAPGVQGQMAPPLPDSEREKQEPEQGEV-----GKRPGQAQALEEAGDLPEDP 577
Cdd:TIGR00927  632 KGDVAEAEHTgeRTGEEGERPTE-AEGENGEESGGEAEQEGETETKGENESEGEIpaerkGEQEGEGEIEAKEADHKGET 710

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   578 QKVPEADGQPAVQPAKEDLGPGDRGlhPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDH------GGK 651
Cdd:TIGR00927  711 EAEEVEHEGETEAEGTEDEGEIETG--EEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDegeiqaGED 788

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485   652 PPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHK 731
Cdd:TIGR00927  789 GEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDGGDSEEEEE 868

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 576077485   732 EihqQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETV 773
Cdd:TIGR00927  869 E---EEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQAI 907
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 532-680 8.50e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 39.75  E-value: 8.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576077485  532 PGVQGQMAPPLPDSEREKQEPEQG--EVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQA 609
Cdd:NF040712  170 PGAHGGTVTALDDEARWLIDPDFGrpLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRR 249

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 576077485  610 VLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPG-PGLPPEPREQRDVERAGG 680
Cdd:NF040712  250 AGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPaAPAAPEAEEPARPEPPPA 321
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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