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Conserved domains on  [gi|575508803|ref|XP_006683672|]
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uncharacterized protein CANTEDRAFT_101113 [Yamadazyma tenuis ATCC 10573]

Protein Classification

CENP-Q domain-containing protein( domain architecture ID 10586783)

CENP-Q domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CENP-Q pfam13094
CENP-Q, a CENPA-CAD centromere complex subunit; CENP-Q is one of the components that assembles ...
 157-320 1.85e-27

CENP-Q, a CENPA-CAD centromere complex subunit; CENP-Q is one of the components that assembles onto the CENPA-nucleosome distal (CAD) centromere. The centromere, which is the basic element of chromosome inheritance, is epigenetically determined in mammals. CENP-A, the centromere-specific histone H3 variant, assembles an array of nucleosomes and it is this that seems to be the prime candidate for specifying centromere identity. CENPA nucleosomes directly recruit a proximal CENPA-nucleosome-associated complex (NAC) comprised of CENP-M, CENP-N and CENP-T, CENP-U(50), CENP-C and CENP-H. Assembly of the CENPA NAC at centromeres is dependent on CENP-M, CENP-N and CENP-T. Additionally, there are seven other subunits which make up the CENPA-nucleosome distal (CAD) centromere, CENP-K, CENP-L, CENP-O, CENP-P, CENP-Q, CENP-R and CENP-S, also assembling on the CENP-A NAC. Fta7 is the equivalent component of the fission yeast Sim4 complex.


:

Pssm-ID: 432970 [Multi-domain]  Cd Length: 159  Bit Score: 105.06  E-value: 1.85e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575508803  157 FKRRLQTTKLPRrvsihstnpqnDENKYVLNHDILNRRKTFLETYLSAELKQLKDLTKTYNKIELNYKSDLEYLKEFNKT 236
Cdd:pfam13094   1 LLRRLARLPFPP-----------GGKEKVLDFEKLLDRNKALEAQLSAELHSLELLEEEIEKEEALLESDEEYLEELEKN 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575508803  237 VEANESKMSQEvytKKTTMNLKYSDTSNLDSDVTSSNV---------RFTPREDDEVNELLEKLDSGLKRVSGNSKDLID 307
Cdd:pfam13094  70 AKAEARERKEK---LKKEHPLLQEDDSGVLSLPELSSDlglgdtdfsLFDPTLDEELLPLLEQLQKHLESMQGNLAQLEG 146

                         170
                  ....*....|...
gi 575508803  308 FHERLQNFQDSLD 320
Cdd:pfam13094 147 LNEAIERAYAALD 159
 
Name Accession Description Interval E-value
CENP-Q pfam13094
CENP-Q, a CENPA-CAD centromere complex subunit; CENP-Q is one of the components that assembles ...
 157-320 1.85e-27

CENP-Q, a CENPA-CAD centromere complex subunit; CENP-Q is one of the components that assembles onto the CENPA-nucleosome distal (CAD) centromere. The centromere, which is the basic element of chromosome inheritance, is epigenetically determined in mammals. CENP-A, the centromere-specific histone H3 variant, assembles an array of nucleosomes and it is this that seems to be the prime candidate for specifying centromere identity. CENPA nucleosomes directly recruit a proximal CENPA-nucleosome-associated complex (NAC) comprised of CENP-M, CENP-N and CENP-T, CENP-U(50), CENP-C and CENP-H. Assembly of the CENPA NAC at centromeres is dependent on CENP-M, CENP-N and CENP-T. Additionally, there are seven other subunits which make up the CENPA-nucleosome distal (CAD) centromere, CENP-K, CENP-L, CENP-O, CENP-P, CENP-Q, CENP-R and CENP-S, also assembling on the CENP-A NAC. Fta7 is the equivalent component of the fission yeast Sim4 complex.


Pssm-ID: 432970 [Multi-domain]  Cd Length: 159  Bit Score: 105.06  E-value: 1.85e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575508803  157 FKRRLQTTKLPRrvsihstnpqnDENKYVLNHDILNRRKTFLETYLSAELKQLKDLTKTYNKIELNYKSDLEYLKEFNKT 236
Cdd:pfam13094   1 LLRRLARLPFPP-----------GGKEKVLDFEKLLDRNKALEAQLSAELHSLELLEEEIEKEEALLESDEEYLEELEKN 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575508803  237 VEANESKMSQEvytKKTTMNLKYSDTSNLDSDVTSSNV---------RFTPREDDEVNELLEKLDSGLKRVSGNSKDLID 307
Cdd:pfam13094  70 AKAEARERKEK---LKKEHPLLQEDDSGVLSLPELSSDlglgdtdfsLFDPTLDEELLPLLEQLQKHLESMQGNLAQLEG 146

                         170
                  ....*....|...
gi 575508803  308 FHERLQNFQDSLD 320
Cdd:pfam13094 147 LNEAIERAYAALD 159
 
Name Accession Description Interval E-value
CENP-Q pfam13094
CENP-Q, a CENPA-CAD centromere complex subunit; CENP-Q is one of the components that assembles ...
 157-320 1.85e-27

CENP-Q, a CENPA-CAD centromere complex subunit; CENP-Q is one of the components that assembles onto the CENPA-nucleosome distal (CAD) centromere. The centromere, which is the basic element of chromosome inheritance, is epigenetically determined in mammals. CENP-A, the centromere-specific histone H3 variant, assembles an array of nucleosomes and it is this that seems to be the prime candidate for specifying centromere identity. CENPA nucleosomes directly recruit a proximal CENPA-nucleosome-associated complex (NAC) comprised of CENP-M, CENP-N and CENP-T, CENP-U(50), CENP-C and CENP-H. Assembly of the CENPA NAC at centromeres is dependent on CENP-M, CENP-N and CENP-T. Additionally, there are seven other subunits which make up the CENPA-nucleosome distal (CAD) centromere, CENP-K, CENP-L, CENP-O, CENP-P, CENP-Q, CENP-R and CENP-S, also assembling on the CENP-A NAC. Fta7 is the equivalent component of the fission yeast Sim4 complex.


Pssm-ID: 432970 [Multi-domain]  Cd Length: 159  Bit Score: 105.06  E-value: 1.85e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575508803  157 FKRRLQTTKLPRrvsihstnpqnDENKYVLNHDILNRRKTFLETYLSAELKQLKDLTKTYNKIELNYKSDLEYLKEFNKT 236
Cdd:pfam13094   1 LLRRLARLPFPP-----------GGKEKVLDFEKLLDRNKALEAQLSAELHSLELLEEEIEKEEALLESDEEYLEELEKN 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575508803  237 VEANESKMSQEvytKKTTMNLKYSDTSNLDSDVTSSNV---------RFTPREDDEVNELLEKLDSGLKRVSGNSKDLID 307
Cdd:pfam13094  70 AKAEARERKEK---LKKEHPLLQEDDSGVLSLPELSSDlglgdtdfsLFDPTLDEELLPLLEQLQKHLESMQGNLAQLEG 146

                         170
                  ....*....|...
gi 575508803  308 FHERLQNFQDSLD 320
Cdd:pfam13094 147 LNEAIERAYAALD 159
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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