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Conserved domains on  [gi|571488168|ref|XP_006590858|]
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zinc finger CCCH domain-containing protein 16 [Glycine max]

Protein Classification

zinc finger CCCH domain-containing protein( domain architecture ID 16062263)

zinc finger CCCH domain-containing protein similar to vertebrate nucleoporin NUP42, which is required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm, and Arabidopsis thaliana protein FRIGIDA-ESSENTIAL 1, a transcriptional activator involved in the FRIGIDA-mediated vernalization pathway

CATH:  4.10.1000.10
Gene Ontology:  GO:0046872|GO:0003676
PubMed:  12665246|27990022
SCOP:  3001741

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf_CCCH_4 pfam18345
Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...
 5-23 9.04e-07

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.


:

Pssm-ID: 465719 [Multi-domain]  Cd Length: 19  Bit Score: 44.72  E-value: 9.04e-07
                          10
                  ....*....|....*....
gi 571488168    5 CRNFQRGSCQYGERCRYLH 23
Cdd:pfam18345   1 CKFFLKGRCRYGDKCRFAH 19
 
Name Accession Description Interval E-value
zf_CCCH_4 pfam18345
Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...
 5-23 9.04e-07

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.


Pssm-ID: 465719 [Multi-domain]  Cd Length: 19  Bit Score: 44.72  E-value: 9.04e-07
                          10
                  ....*....|....*....
gi 571488168    5 CRNFQRGSCQYGERCRYLH 23
Cdd:pfam18345   1 CKFFLKGRCRYGDKCRFAH 19
ZnF_C3H1 smart00356
zinc finger;
4-24 5.68e-06

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 42.62  E-value: 5.68e-06
                           10        20
                   ....*....|....*....|.
gi 571488168     4 ICRNFQRGSCQYGERCRYLHV 24
Cdd:smart00356   6 LCKFFKRGYCPRGDRCKFAHP 26
 
Name Accession Description Interval E-value
zf_CCCH_4 pfam18345
Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...
 5-23 9.04e-07

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.


Pssm-ID: 465719 [Multi-domain]  Cd Length: 19  Bit Score: 44.72  E-value: 9.04e-07
                          10
                  ....*....|....*....
gi 571488168    5 CRNFQRGSCQYGERCRYLH 23
Cdd:pfam18345   1 CKFFLKGRCRYGDKCRFAH 19
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
2-25 3.08e-06

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 43.34  E-value: 3.08e-06
                          10        20
                  ....*....|....*....|....*
gi 571488168    2 RDICRNFQR-GSCQYGERCRYLHVQ 25
Cdd:pfam00642   3 TELCRFFLRtGYCKYGDRCKFAHGQ 27
ZnF_C3H1 smart00356
zinc finger;
4-24 5.68e-06

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 42.62  E-value: 5.68e-06
                           10        20
                   ....*....|....*....|.
gi 571488168     4 ICRNFQRGSCQYGERCRYLHV 24
Cdd:smart00356   6 LCKFFKRGYCPRGDRCKFAHP 26
zf-CCCH_4 pfam18044
CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and ...
 4-23 1.77e-05

CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and one histidine to coordinate the zinc ion. This domain is found in a wide variety of proteins such as E3 ligases.


Pssm-ID: 465626  Cd Length: 22  Bit Score: 41.03  E-value: 1.77e-05
                          10        20
                  ....*....|....*....|
gi 571488168    4 ICRNFQRGSCQYGERCRYLH 23
Cdd:pfam18044   2 LCRYFQKGGCRYGDNCRFSH 21
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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