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Conserved domains on  [gi|570745508|gb|AHF16020|]
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membrane protein [Niabella soli DSM 19437]

Protein Classification

SusC/RagA family TonB-linked outer membrane protein( domain architecture ID 13730627)

SusC/RagA family TonB-linked outer membrane protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OMP_RagA_SusC super family cl37378
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 107-1094 1.38e-147

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


The actual alignment was detected with superfamily member TIGR04056:

Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 467.07  E-value: 1.38e-147
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   107 IMVKGVVTNAKGEPVAGATVS-SNKGKATITNDAGAYSIEVSEFDELTFSYVGYTTQVIKVNSQGTINVILQEANRALEE 185
Cdd:TIGR04056    1 ITVTGVVVDETGEPLIGASVVvKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   186 VVVTALGIKRQeKALGYATQKVGGSAVQAVKTVDLGTSLTGQVSGLVVKNTT-EFNKTPGIQLRG-------ETPLLVIN 257
Cdd:TIGR04056   81 VVVVGYGTQKK-KSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSgEPGGDAEIWIRGissfggnNSPLYVID 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   258 GVPYGNmSLRDVPADDIETIDVLKGATASALYGSRGGAGAIMITTKSGKGKGFAIDVNSNNMFTlGYTAIPKVQTSYGHG 337
Cdd:TIGR04056  160 GVPRDN-GLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISYNAEFGFS-TPTRLPEMLNAYEYA 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   338 ldgkiatDYVWGPKLDRGDSALQWNPVTKQSQMMPLvsSGRDNLKN-------FLQTGVISNNNISVTQSGDNGFFRAGL 410
Cdd:TIGR04056  238 -------ELYNEALLNRGSSPPDIYTDEEIEAYRNG--LDPDLYPNtdwqdeiFKRTAFNQRHNLSVSGGTEKARYYVSL 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   411 NYIYNKGEWPNARLQIINYTMSGQMKLGKKFDLSASMGYTWQQSPQNVGGGYDNQGYLYQMLMWTGPDYDIRQYRDYWVT 490
Cdd:TIGR04056  309 GYYNEEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNPGGSTSNIWGALMLFPRGTPYSTPPVYSDGYYPA 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   491 PNlkqNWLYDawYDNPWLIAYEKLLSNQNNKLNSSLTANYSFTPHLKLMFRTGYDYYSNETTQRNPANVNSDRGGFSTSG 570
Cdd:TIGR04056  389 YN---SGNTS--LQNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSNYKNKKYYKNPYYYNATGGANNG 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   571 LFRDNLAWGFSTNNDLILTYDRNFGKFGLNALAGGSVYYYEdrmqgaATANGLSIPGWYSLanaapSTAVGVNSINNSYS 650
Cdd:TIGR04056  464 YYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQENK------SSSYGGLLDDLPSL-----DAGTSDASVSGSDS 532

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   651 FYRKQtnGAYGKASFSYDNGVYLDITGRNDWASTQQASQRSYFYPSAGLSFILSRY---LKLPDWVDLLKLRGSWTISKN 727
Cdd:TIGR04056  533 EYRLQ--SLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEEkfmKKLKKWLSFLKLRASYGIVGN 610

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   728 V--------LDVYSTNrsfSSGTSFGlISNSYPSNLLGESLLPSTNRTWET------GIASYLFKSRLHVDATYFAKLYY 793
Cdd:TIGR04056  611 DnigdrypyLSLYNLG---DGGYNFG-TNNGTSVTGITESRYGNPNLKWEKtkkwnlGLDLGFFNNRLSLTVDYYYKKTK 686

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   794 NRQVSASVSGASGFTSTLVNTNETYArRGMEITVDGDAIKTGKFKWHSTINWSYDHKYWVNLD-SVYTTDDNWHKK---- 868
Cdd:TIGR04056  687 DILQSRSLPSVTGYSSPYANIGKVKN-KGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILELDeGAYLPVKYPYISkegg 765

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   869 -------NIRLDVYTTKEWARDPSGN-------YINVGGKPIKNPYNTQ-IGYGD-PNYSFGFINDFTWKDFVLGINIDG 932
Cdd:TIGR04056  766 pigqiygYIADGLFKDDDSPKQTFGNvrpgdikYKDVNGDGKIDDDDRVpIGYSNtPDLTYGFGNSFSYKGFDLSALFQG 845

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   933 RIGGLMYDYiwDKMFDTGSNPETDNQFR--YNQVVNKDNTYTapgvkiasgkasydKYGNLisdTRTYAPNDVPIGYQTY 1010
Cdd:TIGR04056  846 SGGGDVFND--GRGFYPFNGGDWGNVLKivADNRWTPENPNA--------------DYPRL---SYGDSNNSNNYQASTR 906

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  1011 ARnfRDGhygimseSFVKLRQVSIGYNLPKNAIKSVrGLRSASVSVTGQNLLLITKFKFSDPDIDTEDLNA-PSQRMVGF 1089
Cdd:TIGR04056  907 WL--EDG-------SYLRLKNLTLGYTLPKKWLKKI-GISNLRVYFSGQNLFTFSKYKGWDPELQGNDGGAyPLQRTFSF 976


                   ....*
gi 570745508  1090 NIKLG 1094
Cdd:TIGR04056  977 GVNLT 981
STN pfam07660
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 50-98 6.97e-03

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


:

Pssm-ID: 429580 [Multi-domain]  Cd Length: 51  Bit Score: 35.57  E-value: 6.97e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 570745508    50 FVYSNKVVDDIGTINIKVVNTPVLDLVSRILNGSALEFQQMDNKLIVIR 98
Cdd:pfam07660    2 ILYDSDLVDGKQSVSLNVGNVTLEEALDQLLAGTGLSYEIGGNTIVLRP 50
 
Name Accession Description Interval E-value
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 107-1094 1.38e-147

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 467.07  E-value: 1.38e-147
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   107 IMVKGVVTNAKGEPVAGATVS-SNKGKATITNDAGAYSIEVSEFDELTFSYVGYTTQVIKVNSQGTINVILQEANRALEE 185
Cdd:TIGR04056    1 ITVTGVVVDETGEPLIGASVVvKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   186 VVVTALGIKRQeKALGYATQKVGGSAVQAVKTVDLGTSLTGQVSGLVVKNTT-EFNKTPGIQLRG-------ETPLLVIN 257
Cdd:TIGR04056   81 VVVVGYGTQKK-KSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSgEPGGDAEIWIRGissfggnNSPLYVID 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   258 GVPYGNmSLRDVPADDIETIDVLKGATASALYGSRGGAGAIMITTKSGKGKGFAIDVNSNNMFTlGYTAIPKVQTSYGHG 337
Cdd:TIGR04056  160 GVPRDN-GLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISYNAEFGFS-TPTRLPEMLNAYEYA 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   338 ldgkiatDYVWGPKLDRGDSALQWNPVTKQSQMMPLvsSGRDNLKN-------FLQTGVISNNNISVTQSGDNGFFRAGL 410
Cdd:TIGR04056  238 -------ELYNEALLNRGSSPPDIYTDEEIEAYRNG--LDPDLYPNtdwqdeiFKRTAFNQRHNLSVSGGTEKARYYVSL 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   411 NYIYNKGEWPNARLQIINYTMSGQMKLGKKFDLSASMGYTWQQSPQNVGGGYDNQGYLYQMLMWTGPDYDIRQYRDYWVT 490
Cdd:TIGR04056  309 GYYNEEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNPGGSTSNIWGALMLFPRGTPYSTPPVYSDGYYPA 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   491 PNlkqNWLYDawYDNPWLIAYEKLLSNQNNKLNSSLTANYSFTPHLKLMFRTGYDYYSNETTQRNPANVNSDRGGFSTSG 570
Cdd:TIGR04056  389 YN---SGNTS--LQNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSNYKNKKYYKNPYYYNATGGANNG 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   571 LFRDNLAWGFSTNNDLILTYDRNFGKFGLNALAGGSVYYYEdrmqgaATANGLSIPGWYSLanaapSTAVGVNSINNSYS 650
Cdd:TIGR04056  464 YYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQENK------SSSYGGLLDDLPSL-----DAGTSDASVSGSDS 532

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   651 FYRKQtnGAYGKASFSYDNGVYLDITGRNDWASTQQASQRSYFYPSAGLSFILSRY---LKLPDWVDLLKLRGSWTISKN 727
Cdd:TIGR04056  533 EYRLQ--SLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEEkfmKKLKKWLSFLKLRASYGIVGN 610

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   728 V--------LDVYSTNrsfSSGTSFGlISNSYPSNLLGESLLPSTNRTWET------GIASYLFKSRLHVDATYFAKLYY 793
Cdd:TIGR04056  611 DnigdrypyLSLYNLG---DGGYNFG-TNNGTSVTGITESRYGNPNLKWEKtkkwnlGLDLGFFNNRLSLTVDYYYKKTK 686

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   794 NRQVSASVSGASGFTSTLVNTNETYArRGMEITVDGDAIKTGKFKWHSTINWSYDHKYWVNLD-SVYTTDDNWHKK---- 868
Cdd:TIGR04056  687 DILQSRSLPSVTGYSSPYANIGKVKN-KGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILELDeGAYLPVKYPYISkegg 765

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   869 -------NIRLDVYTTKEWARDPSGN-------YINVGGKPIKNPYNTQ-IGYGD-PNYSFGFINDFTWKDFVLGINIDG 932
Cdd:TIGR04056  766 pigqiygYIADGLFKDDDSPKQTFGNvrpgdikYKDVNGDGKIDDDDRVpIGYSNtPDLTYGFGNSFSYKGFDLSALFQG 845

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   933 RIGGLMYDYiwDKMFDTGSNPETDNQFR--YNQVVNKDNTYTapgvkiasgkasydKYGNLisdTRTYAPNDVPIGYQTY 1010
Cdd:TIGR04056  846 SGGGDVFND--GRGFYPFNGGDWGNVLKivADNRWTPENPNA--------------DYPRL---SYGDSNNSNNYQASTR 906

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  1011 ARnfRDGhygimseSFVKLRQVSIGYNLPKNAIKSVrGLRSASVSVTGQNLLLITKFKFSDPDIDTEDLNA-PSQRMVGF 1089
Cdd:TIGR04056  907 WL--EDG-------SYLRLKNLTLGYTLPKKWLKKI-GISNLRVYFSGQNLFTFSKYKGWDPELQGNDGGAyPLQRTFSF 976


                   ....*
gi 570745508  1090 NIKLG 1094
Cdd:TIGR04056  977 GVNLT 981
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
183-907 9.71e-33

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 135.73  E-value: 9.71e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  183 LEEVVVTALGIKRQEKALGYATQKVGGSAVQAVKTVDLGTSLtGQVSGLVVknTTEFNKTPGIQLRG-----ETPLLVIN 257
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSV--TSAGGGAGQISIRGfggggNRVLVLVD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  258 GVPYGNMS-----LRDVPADDIETIDVLKGAtASALYGSRGGAGAIMITTKSGKGKGFAidvnsnnmftlgytaipKVQT 332
Cdd:COG1629    78 GVPLNDPSggdggLSYIDPEDIERVEVLRGP-SSALYGSGALGGVINIVTKKPKDGKGG-----------------EVSA 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  333 SYGhgldgkiatdyvwgpkldrgdsalqwnpvtkqsqmmplvSSGRdnlknflqtgviSNNNISVTQSGDNGFFRAGLNY 412
Cdd:COG1629   140 SYG---------------------------------------SYGT------------YRASLSLSGGNGKLAYRLSASY 168

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  413 IYNKGEWPNARLQIINYTMSGQMKLGKKFDLSASMGYTWQQspqnvgggYDNQGYLyqmlmwTGPDYDIRQYRDYWVTPN 492
Cdd:COG1629   169 RDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSD--------QDSPGYL------TLAALRPRGAMDDGTNPY 234

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  493 LKQNwlydawydnpwliayekllsNQNNKLNSSLTANYS-FTPHLKLMFRTGYDYYSNETTQRNPANVNSDRGGFSTSgl 571
Cdd:COG1629   235 SNDT--------------------DDNTRDRYSLSLEYEhLGDGLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQTD-- 292

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  572 fRDNLAWGFSTNndliLTYDRNFGKfGLNALAGGSVYYYEDRMQGAATANGLSIPGWYSlanaapstavgvnsiNNSYSF 651
Cdd:COG1629   293 -FDNRTYGLELR----LTYDLGFGG-KHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLT---------------SGADDD 351

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  652 YRKQTNGAYGKASFSYDNGVYLDITGRNDWAS----------TQQASQRSY--FYPSAGLSFILSrylklpdwvDLLKLR 719
Cdd:COG1629   352 GTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSydvddtvtgtDSASGSRSYsaFSPSLGLTYQLS---------PNLSLY 422

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  720 GSWTisknvldvystnRSFSSGTSFGLISNSYPSNLLGESLL-PSTNRTWETGIASYLFKSRLHVDATYFAKLYYNRQVS 798
Cdd:COG1629   423 ASYS------------RGFRAPTFGELYANGTDPYSVGNPDLkPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILS 490

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  799 ASVSGASGFTSTLVNTNETYaRRGMEITVDGDAIKtgkfKWHSTINWSY-DHKYWVNLDSVYTTDDNW------HKKNIR 871
Cdd:COG1629   491 VPLPNDSGFSTYYTNAGKAR-SYGVELELSYQLTP----GLSLNASYSYtDAKFDDDTDGSADLDGNRlpgvppLTANLG 565

                         730       740       750
                  ....*....|....*....|....*....|....*...
gi 570745508  872 LDVYTTKEWARDPSGNYinVGGKPIK--NPYNTQIGYG 907
Cdd:COG1629   566 LTYEFPGGWSLGLGVRY--VGDRYLDdaNTQGAPGGYT 601
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
 109-188 4.13e-15

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 71.47  E-value: 4.13e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   109 VKGVVTNAK-GEPVAGATVS-SNKGKATITNDAGAYSIEVSEFDE--LTFSYVGYTTQVIKVNSQG----TINVILQEAN 180
Cdd:pfam13715    1 ISGTVVDENtGEPLPGATVYvKGTTKGTVTDADGNFELKNLPAGTytLVVSFVGYKTQEKKVTVSNdntlDVNFLLKEDA 80


                   ....*...
gi 570745508   181 RALEEVVV 188
Cdd:pfam13715   81 LLLDEVVV 88
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 244-863 1.02e-09

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 62.47  E-value: 1.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  244 GIQLRGETP---LLVINGVPY------GNMSLRDVPADDIETIDVLKGAtASALYGSRGGAGAIMITTKSGKGKGFAidv 314
Cdd:cd01347    40 TISIRGFGPdrtLVLVDGLPLassnygRGVDLNTIPPELIERVEVLKGP-SSALYGSGAIGGVVNIITKRPTDEFGG--- 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  315 nsnnMFTLGYTAIPKVQTSYGHgldgkiatdyvwgpkLDRGDSAlqwnpvtkqsqmmplvsSGRDNLKNFLqtgvisnnn 394
Cdd:cd01347   116 ----SVTAGYGSDNSGSSGGGG---------------FDVSGAL-----------------ADDGAFGARL--------- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  395 isvtqsgdNGFFRAGLNYIYNKGEWPNARLQIINYTMSGQMKLGKKFDLSASMGYTWQQSPQNVGGGYDNqgylyqmlmW 474
Cdd:cd01347   151 --------YGAYRDGDGTIDGDGQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPAN---------G 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  475 TGPDYDIRQYRDYWVTPNLKQNWLYDAWYDNPWliayekllSNQNNKLNSSLTANYsftphlklmfrtgydYYSNETTQR 554
Cdd:cd01347   214 TGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGL--------EHDLNDTGWTLRANL---------------SYSYTDNDG 270

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  555 NPANVNSDRGGFSTSGLFRDNLAWGFSTNNDLILTYDRNFGKFGLN-ALAGGSVYYYEdrmqgaatanglsipgwyslan 633
Cdd:cd01347   271 DPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLNAPFGTGPVAhTLTLGVEYRRE---------------------- 328

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  634 aapstavgvnsinnsySFYRKQTnGAYGKASFSYDNGVYLDITGRNDWASTQQASQ----------RSYFYPSAGLSFil 703
Cdd:cd01347   329 ----------------ELDEKQT-ALYAQDTIELTDDLTLTLGLRYDHYDQDSKDTiaggttakksYSHWSPSLGLVY-- 389

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  704 srylKLPDWVDlLKLRGSWTISKNVLDVYSTNRSFSSGTSFGlisnsypsnllGESLLPSTNRTWETGIASYlFKSRLHV 783
Cdd:cd01347   390 ----KLTDGLS-LYASYSQGFRAPSLGELYGGGSHGGTAAVG-----------NPNLKPEKSKQYELGLKYD-PGDGLTL 452

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  784 DATYFAKLYYNRQVSASVSGASGFTSTLVNTNETYArRGMEITVDGDAikTGKFKWhsTINWSYDHKYWVNLDSVYTTDD 863
Cdd:cd01347   453 SAALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARI-RGVELEASYDL--TDGLGL--TGSYTYTDTEVKRTDGATTGNR 527
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
245-308 3.37e-03

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 41.55  E-value: 3.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  245 IQLRG---ETPLLVINGVP--------YGNMSLRD-------VPADDIETIDVLKGAtASALYGSRGGAGAIMITTKSGK 306
Cdd:PRK13524   99 IDIRGmgpENTLILIDGKPvssrnsvrYGWRGERDtrgdtnwVPPEMIERIEVLRGP-AAARYGNGAAGGVVNIITKKPT 177


                  ..
gi 570745508  307 GK 308
Cdd:PRK13524  178 GE 179
STN pfam07660
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 50-98 6.97e-03

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 429580 [Multi-domain]  Cd Length: 51  Bit Score: 35.57  E-value: 6.97e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 570745508    50 FVYSNKVVDDIGTINIKVVNTPVLDLVSRILNGSALEFQQMDNKLIVIR 98
Cdd:pfam07660    2 ILYDSDLVDGKQSVSLNVGNVTLEEALDQLLAGTGLSYEIGGNTIVLRP 50
 
Name Accession Description Interval E-value
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 107-1094 1.38e-147

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 467.07  E-value: 1.38e-147
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   107 IMVKGVVTNAKGEPVAGATVS-SNKGKATITNDAGAYSIEVSEFDELTFSYVGYTTQVIKVNSQGTINVILQEANRALEE 185
Cdd:TIGR04056    1 ITVTGVVVDETGEPLIGASVVvKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   186 VVVTALGIKRQeKALGYATQKVGGSAVQAVKTVDLGTSLTGQVSGLVVKNTT-EFNKTPGIQLRG-------ETPLLVIN 257
Cdd:TIGR04056   81 VVVVGYGTQKK-KSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSgEPGGDAEIWIRGissfggnNSPLYVID 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   258 GVPYGNmSLRDVPADDIETIDVLKGATASALYGSRGGAGAIMITTKSGKGKGFAIDVNSNNMFTlGYTAIPKVQTSYGHG 337
Cdd:TIGR04056  160 GVPRDN-GLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISYNAEFGFS-TPTRLPEMLNAYEYA 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   338 ldgkiatDYVWGPKLDRGDSALQWNPVTKQSQMMPLvsSGRDNLKN-------FLQTGVISNNNISVTQSGDNGFFRAGL 410
Cdd:TIGR04056  238 -------ELYNEALLNRGSSPPDIYTDEEIEAYRNG--LDPDLYPNtdwqdeiFKRTAFNQRHNLSVSGGTEKARYYVSL 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   411 NYIYNKGEWPNARLQIINYTMSGQMKLGKKFDLSASMGYTWQQSPQNVGGGYDNQGYLYQMLMWTGPDYDIRQYRDYWVT 490
Cdd:TIGR04056  309 GYYNEEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNPGGSTSNIWGALMLFPRGTPYSTPPVYSDGYYPA 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   491 PNlkqNWLYDawYDNPWLIAYEKLLSNQNNKLNSSLTANYSFTPHLKLMFRTGYDYYSNETTQRNPANVNSDRGGFSTSG 570
Cdd:TIGR04056  389 YN---SGNTS--LQNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSNYKNKKYYKNPYYYNATGGANNG 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   571 LFRDNLAWGFSTNNDLILTYDRNFGKFGLNALAGGSVYYYEdrmqgaATANGLSIPGWYSLanaapSTAVGVNSINNSYS 650
Cdd:TIGR04056  464 YYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQENK------SSSYGGLLDDLPSL-----DAGTSDASVSGSDS 532

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   651 FYRKQtnGAYGKASFSYDNGVYLDITGRNDWASTQQASQRSYFYPSAGLSFILSRY---LKLPDWVDLLKLRGSWTISKN 727
Cdd:TIGR04056  533 EYRLQ--SLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEEkfmKKLKKWLSFLKLRASYGIVGN 610

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   728 V--------LDVYSTNrsfSSGTSFGlISNSYPSNLLGESLLPSTNRTWET------GIASYLFKSRLHVDATYFAKLYY 793
Cdd:TIGR04056  611 DnigdrypyLSLYNLG---DGGYNFG-TNNGTSVTGITESRYGNPNLKWEKtkkwnlGLDLGFFNNRLSLTVDYYYKKTK 686

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   794 NRQVSASVSGASGFTSTLVNTNETYArRGMEITVDGDAIKTGKFKWHSTINWSYDHKYWVNLD-SVYTTDDNWHKK---- 868
Cdd:TIGR04056  687 DILQSRSLPSVTGYSSPYANIGKVKN-KGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILELDeGAYLPVKYPYISkegg 765

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   869 -------NIRLDVYTTKEWARDPSGN-------YINVGGKPIKNPYNTQ-IGYGD-PNYSFGFINDFTWKDFVLGINIDG 932
Cdd:TIGR04056  766 pigqiygYIADGLFKDDDSPKQTFGNvrpgdikYKDVNGDGKIDDDDRVpIGYSNtPDLTYGFGNSFSYKGFDLSALFQG 845

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   933 RIGGLMYDYiwDKMFDTGSNPETDNQFR--YNQVVNKDNTYTapgvkiasgkasydKYGNLisdTRTYAPNDVPIGYQTY 1010
Cdd:TIGR04056  846 SGGGDVFND--GRGFYPFNGGDWGNVLKivADNRWTPENPNA--------------DYPRL---SYGDSNNSNNYQASTR 906

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  1011 ARnfRDGhygimseSFVKLRQVSIGYNLPKNAIKSVrGLRSASVSVTGQNLLLITKFKFSDPDIDTEDLNA-PSQRMVGF 1089
Cdd:TIGR04056  907 WL--EDG-------SYLRLKNLTLGYTLPKKWLKKI-GISNLRVYFSGQNLFTFSKYKGWDPELQGNDGGAyPLQRTFSF 976


                   ....*
gi 570745508  1090 NIKLG 1094
Cdd:TIGR04056  977 GVNLT 981
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
183-907 9.71e-33

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 135.73  E-value: 9.71e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  183 LEEVVVTALGIKRQEKALGYATQKVGGSAVQAVKTVDLGTSLtGQVSGLVVknTTEFNKTPGIQLRG-----ETPLLVIN 257
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSV--TSAGGGAGQISIRGfggggNRVLVLVD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  258 GVPYGNMS-----LRDVPADDIETIDVLKGAtASALYGSRGGAGAIMITTKSGKGKGFAidvnsnnmftlgytaipKVQT 332
Cdd:COG1629    78 GVPLNDPSggdggLSYIDPEDIERVEVLRGP-SSALYGSGALGGVINIVTKKPKDGKGG-----------------EVSA 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  333 SYGhgldgkiatdyvwgpkldrgdsalqwnpvtkqsqmmplvSSGRdnlknflqtgviSNNNISVTQSGDNGFFRAGLNY 412
Cdd:COG1629   140 SYG---------------------------------------SYGT------------YRASLSLSGGNGKLAYRLSASY 168

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  413 IYNKGEWPNARLQIINYTMSGQMKLGKKFDLSASMGYTWQQspqnvgggYDNQGYLyqmlmwTGPDYDIRQYRDYWVTPN 492
Cdd:COG1629   169 RDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSD--------QDSPGYL------TLAALRPRGAMDDGTNPY 234

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  493 LKQNwlydawydnpwliayekllsNQNNKLNSSLTANYS-FTPHLKLMFRTGYDYYSNETTQRNPANVNSDRGGFSTSgl 571
Cdd:COG1629   235 SNDT--------------------DDNTRDRYSLSLEYEhLGDGLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQTD-- 292

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  572 fRDNLAWGFSTNndliLTYDRNFGKfGLNALAGGSVYYYEDRMQGAATANGLSIPGWYSlanaapstavgvnsiNNSYSF 651
Cdd:COG1629   293 -FDNRTYGLELR----LTYDLGFGG-KHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLT---------------SGADDD 351

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  652 YRKQTNGAYGKASFSYDNGVYLDITGRNDWAS----------TQQASQRSY--FYPSAGLSFILSrylklpdwvDLLKLR 719
Cdd:COG1629   352 GTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSydvddtvtgtDSASGSRSYsaFSPSLGLTYQLS---------PNLSLY 422

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  720 GSWTisknvldvystnRSFSSGTSFGLISNSYPSNLLGESLL-PSTNRTWETGIASYLFKSRLHVDATYFAKLYYNRQVS 798
Cdd:COG1629   423 ASYS------------RGFRAPTFGELYANGTDPYSVGNPDLkPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILS 490

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  799 ASVSGASGFTSTLVNTNETYaRRGMEITVDGDAIKtgkfKWHSTINWSY-DHKYWVNLDSVYTTDDNW------HKKNIR 871
Cdd:COG1629   491 VPLPNDSGFSTYYTNAGKAR-SYGVELELSYQLTP----GLSLNASYSYtDAKFDDDTDGSADLDGNRlpgvppLTANLG 565

                         730       740       750
                  ....*....|....*....|....*....|....*...
gi 570745508  872 LDVYTTKEWARDPSGNYinVGGKPIK--NPYNTQIGYG 907
Cdd:COG1629   566 LTYEFPGGWSLGLGVRY--VGDRYLDdaNTQGAPGGYT 601
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 176-925 3.53e-26

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 114.95  E-value: 3.53e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  176 LQEANRALEEVVVTALGIKRQEKALGYATQKVGGSAVQAVKTVDLGTSLTgQVSGLVVKNTTEFNKTPGIQLRGETP--- 252
Cdd:COG4771    20 LAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALR-LLPGVSVTRSGGRGGSSGISIRGLGGdrv 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  253 LLVINGVP------YGNMSLRDVPADDIETIDVLKGAtASALYGSRGGAGAIMITTKSGKGKGFAidvnsnnmftlgyta 326
Cdd:COG4771    99 LVLIDGVPvnnpalGGGGDLSYIPPDDIERIEVIRGP-ASALYGSDAIGGVINIITKKPTDELEG--------------- 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  327 ipKVQTSYGHGLDGKIatdyvwgpkldrgdsalqwnpvtkqsqmmplvssgrdnlknflqtgvisNNNISVTQSGDNGFF 406
Cdd:COG4771   163 --SVSLGYGSNGNGTY-------------------------------------------------SGSLSLGGPGDKLSF 191

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  407 RAGLNY--------IYNKGEWPNARLQIINYTMSGQMKLGKKFDLSASMGYTWqqspQNVGGGYDNQGYlyqmlmwTGPD 478
Cdd:COG4771   192 LLSGSYrdrdgyldYRNGGFVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSR----QDRDGGPPTLGD-------TEIS 260

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  479 YDIRQYRDYwvtpnlkqnwlydawydnpwliayekllsnQNNKLNSSLTANYSFTPHLKLMFrtgydYYSNETTQRNPAN 558
Cdd:COG4771   261 SDNAGDRDT------------------------------TTDRGNYSLRYNGDLGDNLDLSL-----YYSRTDRDSTNGS 305

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  559 VNSDRGGFSTSglfrDNLAWGFSTNNDLILTYDRNFgKFGLNalaggsvyYYEDRMQGAATANGLSipgwyslanaapst 638
Cdd:COG4771   306 LGGSTGSFSDS----DDTTYGLELDLTYPLGGNHTL-TLGAE--------YRYDDLDSSSFLGGAD-------------- 358

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  639 avgvnsinnsysfYRKQTNGAYGKASFSYDNGVYLDITGRNDWASTQQASQRSYFYPSAGLSFILSrylklpdwvDLLKL 718
Cdd:COG4771   359 -------------ASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGASNYTAFSPRLGLRYDLS---------DNLTL 416

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  719 RGSWTISKNVLDVYSTNRSFSSGTSFGLISNsypsnllgESLLPSTNRTWETGIASYLFKSRLHVDATYFAKLYYNRQVS 798
Cdd:COG4771   417 RASYGRGFRAPSLAELYGSGTGTPGRYVLGN--------PDLKPETSDNYELGLEYRLGNGGLSLSLTGFYTDIKDLIVL 488

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  799 ASVSGASGFTSTLVNTNETYArRGMEITVDGDAIKtgkfKWHSTINWSY-DHKYWVNLDSVYTTDDNWHKKNIRLDVYTT 877
Cdd:COG4771   489 VPVGPGPGDVLQYENVGKART-YGLELELKYRLGK----GLTLTASYTYlDSKIDDGDTGEPLPNVPPHKANLGLDYRLP 563

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....*...
gi 570745508  878 KEWARdpSGNYINVGGKPIKNPYNTQIGYGDPNYSFGFINDFTWKDFV 925
Cdd:COG4771   564 KWWLL--LLLTRYYGGRYVTPPSGRLEGYTPGYTLLDLRASYKLTKNL 609
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
186-340 7.43e-24

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 102.64  E-value: 7.43e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  186 VVVTALGIKRQEKALGYATQKVGGSAVQAVKTVDLGTSLTgQVSGLVVKNTTEFNKTPGIQLRGET---PLLVINGVPY- 261
Cdd:COG4206     1 VVVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQVSSSGGPGSAASISIRGLGsnqTLVLIDGVPLn 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  262 ----GNMSLRDVPADDIETIDVLKGAtASALYGSRGGAGAIMITTKSGKgKGFAIDVNsnnmFTLGYTAIPKVQTSYGHG 337
Cdd:COG4206    80 dpslGGVDLSLIPPDDIERIEVLKGA-ASALYGSDAIGGVINITTKKGK-KGFKGSVS----ASYGSFGTRRLSASLSGG 153


                  ...
gi 570745508  338 LDG 340
Cdd:COG4206   154 AGK 156
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
 109-188 4.13e-15

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 71.47  E-value: 4.13e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   109 VKGVVTNAK-GEPVAGATVS-SNKGKATITNDAGAYSIEVSEFDE--LTFSYVGYTTQVIKVNSQG----TINVILQEAN 180
Cdd:pfam13715    1 ISGTVVDENtGEPLPGATVYvKGTTKGTVTDADGNFELKNLPAGTytLVVSFVGYKTQEKKVTVSNdntlDVNFLLKEDA 80


                   ....*...
gi 570745508   181 RALEEVVV 188
Cdd:pfam13715   81 LLLDEVVV 88
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
177-862 2.07e-11

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 68.03  E-value: 2.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  177 QEANRALEEVVVTALGIKRQE-KALGYATQKVGGSAVQAVKTVDLGTSLtGQVSGLVVKNTTEFNKTPGIQLRGETP--- 252
Cdd:COG4772    17 AEAATTLETVVVTGSRAAEARlKDVPGSVSVVDREELENQAATSLREVL-RRVPGVNVQEEDGFGLRPNIGIRGLGPrrs 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  253 ---LLVINGVP-----YGNMSLR-DVPADDIETIDVLKGAtASALYGSRGGAGAImittksgkgkgfaidvnsnNMFTlg 323
Cdd:COG4772    96 rgiTLLEDGIPiapapYGDPAAYyFPDLERMERIEVLRGA-AALRYGPQTVGGAI-------------------NFVT-- 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  324 yTAIPKVQTsyghgldGKIATDYvwgpkldrgdsalqwnpvtkqsqmmplvssGRDNL-KNFLQTGvisnnnisvtqsGD 402
Cdd:COG4772   154 -RTIPTAFG-------GELRVTG------------------------------GSFGYrRTHASVG------------GT 183

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  403 NGFFRAGLNYIYNKGE-W-PNARLQIINYTMSGQMKLGKKFDLSASMGYTwqqspqnvggGYDNQGYLYQmlmwTGPDYD 480
Cdd:COG4772   184 VGNFGYLVEYSRKRGDgFrDNSGFDINDFNAKLGYRLSDRQELTLKFQYY----------DEDANTPGGL----TDAQFD 249

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  481 IRQYRDYwvTPNlkqnwlydAWYDNPWLIAyekllsnqnnklnsSLTANYSFTPHLKLMFrTGYDYYSNETTQRNPANVN 560
Cdd:COG4772   250 ADPRQSY--RPA--------DQFDTRRTQL--------------SLRYEHQLSDNTTLTT-TAYYNDFSRNWYIRQNTAD 304

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  561 SDRGGFSTSGLFRDNLAWGFSTNndliLTYDRNFGKFGLNALAGGSVYY-YEDRMQGAATANGLSIPGWYSLANAAPSTA 639
Cdd:COG4772   305 PNTPGLGLRGNPRGYRSYGIEPR----LTHRFELGGVPHTLEVGLRYHReEEDRKQYVNTYGQGRSGAGLRRDRRFSADA 380

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  640 VGVNsINNSYSFYRKQ--TNGA-YGKASFSYDNgVYLDITGRNDWASTqqasQRSYFYPSAGLSFILSrylklPDWvdll 716
Cdd:COG4772   381 LAAY-AQNRFELTGRLtlTPGLrYEHIRRDRTD-RYSTRTGGDDSGSN----SYSEFLPGLGLLYQLT-----DNL---- 445

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  717 klrgswtisknvlDVY-STNRSFSSGTSFGLISNSYPSNLLGesllPSTNRTWETGiASYLFKSRLHVDATYFAKLYYNR 795
Cdd:COG4772   446 -------------QLYaNVSRGFEPPTFGDLAYGNGGNPDLK----PEKSWNYELG-TRGRIGNGLSAEVALFYIDYDNE 507

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 570745508  796 QVSASVSGasGFTSTLVNTNETYaRRGMEITVDGDAIKTGKFKWHSTINWSYdhkywvnLDSVYTTD 862
Cdd:COG4772   508 LGSCSAAG--GDRSTFTNAGETR-HQGLELALDYDLLKGGGLGLPLFAAYTY-------TDAEFTSD 564
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 461-830 7.63e-11

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 65.95  E-value: 7.63e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   461 GYDNQGYLYQMLMWTGPDYDIRQY-RDYWVTPNLKQNWLYDAWYDNPWLIAYEKLLSNQNNKLNSSLTANYSFTPHLKLM 539
Cdd:pfam00593    1 GWQLSLDLLGDDTLLTLGYDYSRYtDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLST 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   540 FRTGYDYYSNETTQRNPANVNSDRGGFSTSGLFRDNLAWGFSTNNDLILTYDRNFGKFGLNALAGgsvyyyedrmqgaat 619
Cdd:pfam00593   81 LRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLD--------------- 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   620 anglsipgWYSLANAAPSTAVGVNSINNSYSFYRKQTNGAYGKASFSYDNGVYLDITGRNDWASTQQASQR--------- 690
Cdd:pfam00593  146 --------YRRLDDDAYDPYDPANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNgggdnfsrs 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   691 -SYFYPSAGLSFILSrylklpdwvDLLKLRGSWTisknvldvystnRSFSSGTSFGLISNSYPSNLLG-----ESLLPST 764
Cdd:pfam00593  218 ySAFSPRLGLVYKPT---------DNLSLYASYS------------RGFRAPSLGELYGSGSGGGGGAvaggnPDLKPET 276

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570745508   765 NRTWETGIasYLFKSRLHVDATYFAKLYYNRQVSASVSGASGFTSTLVNTNETYARRGMEITVDGD 830
Cdd:pfam00593  277 SDNYELGL--KYDDGRLSLSLALFYIDIKNLITSDPDGPGLGGTVYTYTNVGKARIRGVELELSGR 340
SusC_RagA_signa TIGR04057
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ...
 273-303 9.13e-10

TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.


Pssm-ID: 274949 [Multi-domain]  Cd Length: 31  Bit Score: 54.51  E-value: 9.13e-10
                           10        20        30
                   ....*....|....*....|....*....|.
gi 570745508   273 DIETIDVLKGATASALYGSRGGAGAIMITTK 303
Cdd:TIGR04057    1 DIESISVLKDASAAAIYGSRGANGVILITTK 31
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 244-863 1.02e-09

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 62.47  E-value: 1.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  244 GIQLRGETP---LLVINGVPY------GNMSLRDVPADDIETIDVLKGAtASALYGSRGGAGAIMITTKSGKGKGFAidv 314
Cdd:cd01347    40 TISIRGFGPdrtLVLVDGLPLassnygRGVDLNTIPPELIERVEVLKGP-SSALYGSGAIGGVVNIITKRPTDEFGG--- 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  315 nsnnMFTLGYTAIPKVQTSYGHgldgkiatdyvwgpkLDRGDSAlqwnpvtkqsqmmplvsSGRDNLKNFLqtgvisnnn 394
Cdd:cd01347   116 ----SVTAGYGSDNSGSSGGGG---------------FDVSGAL-----------------ADDGAFGARL--------- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  395 isvtqsgdNGFFRAGLNYIYNKGEWPNARLQIINYTMSGQMKLGKKFDLSASMGYTWQQSPQNVGGGYDNqgylyqmlmW 474
Cdd:cd01347   151 --------YGAYRDGDGTIDGDGQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPAN---------G 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  475 TGPDYDIRQYRDYWVTPNLKQNWLYDAWYDNPWliayekllSNQNNKLNSSLTANYsftphlklmfrtgydYYSNETTQR 554
Cdd:cd01347   214 TGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGL--------EHDLNDTGWTLRANL---------------SYSYTDNDG 270

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  555 NPANVNSDRGGFSTSGLFRDNLAWGFSTNNDLILTYDRNFGKFGLN-ALAGGSVYYYEdrmqgaatanglsipgwyslan 633
Cdd:cd01347   271 DPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLNAPFGTGPVAhTLTLGVEYRRE---------------------- 328

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  634 aapstavgvnsinnsySFYRKQTnGAYGKASFSYDNGVYLDITGRNDWASTQQASQ----------RSYFYPSAGLSFil 703
Cdd:cd01347   329 ----------------ELDEKQT-ALYAQDTIELTDDLTLTLGLRYDHYDQDSKDTiaggttakksYSHWSPSLGLVY-- 389

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  704 srylKLPDWVDlLKLRGSWTISKNVLDVYSTNRSFSSGTSFGlisnsypsnllGESLLPSTNRTWETGIASYlFKSRLHV 783
Cdd:cd01347   390 ----KLTDGLS-LYASYSQGFRAPSLGELYGGGSHGGTAAVG-----------NPNLKPEKSKQYELGLKYD-PGDGLTL 452

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  784 DATYFAKLYYNRQVSASVSGASGFTSTLVNTNETYArRGMEITVDGDAikTGKFKWhsTINWSYDHKYWVNLDSVYTTDD 863
Cdd:cd01347   453 SAALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARI-RGVELEASYDL--TDGLGL--TGSYTYTDTEVKRTDGATTGNR 527
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 202-297 1.83e-09

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 56.12  E-value: 1.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   202 YATQKVGGSAVQAVKTVDLGTSLTGqVSGLVVKNTTeFNKTPGIQLRG---ETPLLVINGVP-----YGNMSLRDVPADD 273
Cdd:pfam07715    7 GSVSVVTAEDIEDQGATNLADALRG-VPGVSVSSGG-GGGGSSISIRGfgsNRVLVLVDGVPlnsggGGSVDLNSIDPED 84

                           90       100
                   ....*....|....*....|....
gi 570745508   274 IETIDVLKGAtASALYGSRGGAGA 297
Cdd:pfam07715   85 IERVEVLKGP-ASALYGSGAIGGV 107
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
228-864 3.26e-09

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 61.05  E-value: 3.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  228 VSGlVVKNTTEFNKTPGIQLRG---ETPLLViNGVPYGNMSLRDVpaDDIETIDVLKGAtASALYGSRGGAGAIMITTKS 304
Cdd:COG4774    36 VPG-VTFGAGEGGNGDSFSIRGfsaSGDIYV-DGLRDPGQYRRDT--FNLERVEVLKGP-ASVLYGRGSPGGVINLVTKR 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  305 gkgkgfAIDVNSNNmFTLGYtaipkvqTSYGHgldGKIATDYvwgpkldrgdsalqwnpvtkqsqmmplvssgrdnlknf 384
Cdd:COG4774   111 ------PTDEPFTE-VTLTY-------GSDGQ---RRATLDV-------------------------------------- 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  385 lqTGVIsnnnisvtqsGDNGFFRagLNYIYNKGEWP--NARLQIINYTMSGQMKLGKKFDLSASMGYTWQqspqnvgggy 462
Cdd:COG4774   136 --NGPL----------GDDLAYR--LNGMYRDSDSYrdGVDNDRWGIAPSLTWRLGDRTRLTLDYEYQDD---------- 191

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  463 dnqgylyqmlmWTGPDYDIrqyrdYWVTPNLKQNWLYDAWYDNPWliayekllSNQNNKLNS-SLTANYSFTPHLKLMFR 541
Cdd:COG4774   192 -----------DRTPDYGV-----PAVANGRPVDVDRSTFYGQPD--------DYSDSETDSaTLRLEHDFNDNWTLRNA 247

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  542 TGYDYYSNETTQRNPANVNSDrGGFSTSGLFRDNLAWGFStnNDLILTYDRNFGKFGLNALAGGSVYYYEDRMQGAATAN 621
Cdd:COG4774   248 LRYSDYDRDYRNTYPTGGNAT-GTVTRSAYRRDQDNDTLS--NQTDLTGKFDTGGVKHTLLAGVEYSREDSDNARYSGGG 324

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  622 GLsipGWYSLANAAPSTAVGVNSINNSYSFYRKQTNGAYGKASFSYDNGVYLDITGRNDWASTQQASQR----------S 691
Cdd:COG4774   325 TA---PTVNLYNPVYGAPVTGPTLGGADNDSRTDTTGLYLQDTISLTDRWSLLAGLRYDRFDTDYTDRTtgattssyddS 401

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  692 YFYPSAGLSFilsrylKLPDWVdllklrgSwtisknvldVY-STNRSFSSGTSFGLISNSypsnllGESLLPSTNRTWET 770
Cdd:COG4774   402 AFSPRAGLVY------KPTPNL-------S---------LYaSYSTSFNPGGGAPSLSNA------GQALDPEKSRQYEV 453

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  771 GIASYLFKSRLHVDATYFaklYYNRQVSASVSGASGFTSTLVNTNETyarRGMEITVDGDAIKtgkfKWHSTINWSYdhk 850
Cdd:COG4774   454 GVKWDLLDGRLSLTAALF---RIEKTNVRTTDPANPGVYVQTGEQRS---RGVELEATGELTP----GWSVLAGYTY--- 520

                         650
                  ....*....|....
gi 570745508  851 ywvnLDSVYTTDDN 864
Cdd:COG4774   521 ----LDAEITKSAN 530
CarboxypepD_reg pfam13620
Carboxypeptidase regulatory-like domain;
109-176 1.22e-06

Carboxypeptidase regulatory-like domain;


Pssm-ID: 433354 [Multi-domain]  Cd Length: 81  Bit Score: 47.27  E-value: 1.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508   109 VKGVVTNAKGEPVAGATVS-----SNKGKATITNDAGAYSIEVSEFD--ELTFSYVGYTTQVIK-----VNSQGTINVIL 176
Cdd:pfam13620    2 ISGTVTDPSGAPVPGATVTvtntdTGTVRTTTTDADGRYRFPGLPPGtyTVTVSAPGFKTATRTgvtvtAGQTTTLDVTL 81
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 152-788 1.55e-06

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 52.20  E-value: 1.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  152 LTFSYVGYTTQVIKVNSQGTInvilQEANRALEEVVVTAlgikRQEKALGYATQKVGG---------------SAV---- 212
Cdd:COG4773     5 LAGSGLAAAAAGALAQAAAAA----AAEATTLPEVTVTG----TAEGTGGYTAKSSSTatkldtplretpqsvSVVtrql 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  213 ---QAVKTVDlgtSLTGQVSGlVVKNTTEFNKTPGIQLRG-ETPLLVINGVPYGNMSLRDVPADDIETIDVLKGAtASAL 288
Cdd:COG4773    77 iedQGATTLD---DALRNVPG-VTVSSYDGGGRDSFSIRGfSIDNYLRDGLPLGGFGGGQPDTANLERVEVLKGP-AGLL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  289 YGSRGGAGAIMITTKsgkgKGFAIDVNSnnmFTLGYTaipkvqtSYGHGldgKIATDYvwgpkldrgdsalqwnpvtkqs 368
Cdd:COG4773   152 YGAGSPGGLVNLVTK----RPTAEPQGE---VSLSAG-------SWDTY---RATADV---------------------- 192

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  369 qmmplvssgrdnlknflqTGVIsnnnisvtqsGDNGFFRAGLNYIYNKGEwpnarlqiinytmsGQMKLGKKFDLSASMG 448
Cdd:COG4773   193 ------------------GGPL----------NEDGTLRYRLNAAYEDGD--------------SFRDGVDNRRTLIAPS 230

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  449 YTWQQSPQ---NVGGGY--DNQGYLYQMLMWTGPDYDIRQYRdywvtpNLKQNWLYdawydnpwliayekllsNQNNKLN 523
Cdd:COG4773   231 LDWDLTDDttlTLGAEYqdDDSTGDRGFLPLDGTLLDLPRST------NLGEPWDY-----------------YDTETTT 287

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  524 SSLTANYSFTPHLKlmFRTGYDYYSNETTQRN---PANVNSDRGGFSTSGLFRDNLAWGFSTNNDLILTYDrnFGKFGLN 600
Cdd:COG4773   288 LFAELEHRFNDDWS--LRANARYSDSDRDGRSayaYGAPDAATGTLTRYASARDGDSRSDSLDANLNGKFE--TGGLEHT 363

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  601 ALAGGSVYYYEDRmQGAATANGLSIPGWYSLANAAPSTavgvnsiNNSYSFYRKQTNGAYGKASFSYDNGVYLDITGRND 680
Cdd:COG4773   364 LLVGADYSRYDSD-SDSATAGTINIYNPVYGNLPEPDF-------DASDTDTTTRQTGLYAQDQISLTDRLSLLLGGRYD 435

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  681 WASTQQ-----ASQRSY----FYPSAGLSFilsrylKLPDWvdlLKLRGSWTisknvldvystnRSFSSGTSfglISNSy 751
Cdd:COG4773   436 WYETDStnrlgGSTTSYddsaFTPRAGLVY------DLTPG---LSLYASYS------------ESFEPQSG---ADNN- 490

                         650       660       670
                  ....*....|....*....|....*....|....*..
gi 570745508  752 psnllGESLLPSTNRTWETGIASYLFKSRLHVDATYF 788
Cdd:COG4773   491 -----GNPLDPETGKQYEAGVKGELFDGRLNATLAVF 522
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
245-308 3.37e-03

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 41.55  E-value: 3.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570745508  245 IQLRG---ETPLLVINGVP--------YGNMSLRD-------VPADDIETIDVLKGAtASALYGSRGGAGAIMITTKSGK 306
Cdd:PRK13524   99 IDIRGmgpENTLILIDGKPvssrnsvrYGWRGERDtrgdtnwVPPEMIERIEVLRGP-AAARYGNGAAGGVVNIITKKPT 177


                  ..
gi 570745508  307 GK 308
Cdd:PRK13524  178 GE 179
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 244-307 5.88e-03

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 40.47  E-value: 5.88e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 570745508   244 GIQLRGETPLLVINGVP-YGNMSLRDVPADDIETIDVLKGAtASALYGSRGGAGAIMITTKSGKG 307
Cdd:TIGR01783   50 GFGLEVDIDNVYLDGVPlLSRGNLAIVDPAMVERVEVLRGP-ASLLYGGSAPGGVINIVTKRPQD 113
STN pfam07660
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 50-98 6.97e-03

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 429580 [Multi-domain]  Cd Length: 51  Bit Score: 35.57  E-value: 6.97e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 570745508    50 FVYSNKVVDDIGTINIKVVNTPVLDLVSRILNGSALEFQQMDNKLIVIR 98
Cdd:pfam07660    2 ILYDSDLVDGKQSVSLNVGNVTLEEALDQLLAGTGLSYEIGGNTIVLRP 50
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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