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Conserved domains on  [gi|56967112]
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Chain F, T-cell surface glycoprotein CD3 delta chain

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IgC1_CD3_gamma_delta cd07691
Immunoglobulin (Ig)-like domain of Cluster of Differentiation (CD) 3 gamma and delta chains; ...
 4-73 4.75e-31

Immunoglobulin (Ig)-like domain of Cluster of Differentiation (CD) 3 gamma and delta chains; member of the C1-set of IgSF domains; The members here are composed of immunoglobulin (Ig)-like domain of Cluster of Differentiation (CD) 3 gamma and delta chains. CD3 is a T cell surface receptor that is associated with alpha/beta T cell receptors (TCRs). The CD3 complex consists of one gamma, one delta, two epsilon, and two zeta chains. The CD3 subunits form heterodimers as gamma/epsilon, delta/epsilon, and zeta/zeta. The gamma, delta, and epsilon chains each contain an extracellular Ig domain, whereas the extracellular domains of the zeta chains are very small and have unknown structure. The CD3 domain participates in intracellular signaling once the TCR has bound an MHC/antigen complex.


:

Pssm-ID: 409488  Cd Length: 69  Bit Score: 103.39  E-value: 4.75e-31
                       10        20        30        40        50        60        70
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 56967112  4 PIEELEDRVFVNCN--TSITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGTDiykDKESTVQVHYRMCQ 73
Cdd:cd07691  1 SVKENEDKVFLKCNsaSSITWKKGTEGIEASDKTDLDLGSRINDPRGTYQCKGSE---NKEKTLQVHYRMCQ 69
 
Name Accession Description Interval E-value
IgC1_CD3_gamma_delta cd07691
Immunoglobulin (Ig)-like domain of Cluster of Differentiation (CD) 3 gamma and delta chains; ...
 4-73 4.75e-31

Immunoglobulin (Ig)-like domain of Cluster of Differentiation (CD) 3 gamma and delta chains; member of the C1-set of IgSF domains; The members here are composed of immunoglobulin (Ig)-like domain of Cluster of Differentiation (CD) 3 gamma and delta chains. CD3 is a T cell surface receptor that is associated with alpha/beta T cell receptors (TCRs). The CD3 complex consists of one gamma, one delta, two epsilon, and two zeta chains. The CD3 subunits form heterodimers as gamma/epsilon, delta/epsilon, and zeta/zeta. The gamma, delta, and epsilon chains each contain an extracellular Ig domain, whereas the extracellular domains of the zeta chains are very small and have unknown structure. The CD3 domain participates in intracellular signaling once the TCR has bound an MHC/antigen complex.


Pssm-ID: 409488  Cd Length: 69  Bit Score: 103.39  E-value: 4.75e-31
                       10        20        30        40        50        60        70
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 56967112  4 PIEELEDRVFVNCN--TSITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGTDiykDKESTVQVHYRMCQ 73
Cdd:cd07691  1 SVKENEDKVFLKCNsaSSITWKKGTEGIEASDKTDLDLGSRINDPRGTYQCKGSE---NKEKTLQVHYRMCQ 69
Ig_4 pfam16680
T-cell surface glycoprotein CD3 delta chain; This is an immunoglobulin-like domain. It is ...
 9-71 9.15e-24

T-cell surface glycoprotein CD3 delta chain; This is an immunoglobulin-like domain. It is found on the T-cell surface glycoprotein CD3 delta chain. CD3delta and CD3epsilon complex together as part of the T-cell receptor complex.


Pssm-ID: 465231  Cd Length: 63  Bit Score: 84.61  E-value: 9.15e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56967112    9 EDRVFVNCNT---SITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGtdiYKDKESTVQVHYRM 71
Cdd:pfam16680  1 DGKVLLTCNSsskSITWLKDGKGIKSTNTKTLDLGKFSEDPRGLYQCQG---EKKKSSTLQVYYRM 63
 
Name Accession Description Interval E-value
IgC1_CD3_gamma_delta cd07691
Immunoglobulin (Ig)-like domain of Cluster of Differentiation (CD) 3 gamma and delta chains; ...
 4-73 4.75e-31

Immunoglobulin (Ig)-like domain of Cluster of Differentiation (CD) 3 gamma and delta chains; member of the C1-set of IgSF domains; The members here are composed of immunoglobulin (Ig)-like domain of Cluster of Differentiation (CD) 3 gamma and delta chains. CD3 is a T cell surface receptor that is associated with alpha/beta T cell receptors (TCRs). The CD3 complex consists of one gamma, one delta, two epsilon, and two zeta chains. The CD3 subunits form heterodimers as gamma/epsilon, delta/epsilon, and zeta/zeta. The gamma, delta, and epsilon chains each contain an extracellular Ig domain, whereas the extracellular domains of the zeta chains are very small and have unknown structure. The CD3 domain participates in intracellular signaling once the TCR has bound an MHC/antigen complex.


Pssm-ID: 409488  Cd Length: 69  Bit Score: 103.39  E-value: 4.75e-31
                       10        20        30        40        50        60        70
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 56967112  4 PIEELEDRVFVNCN--TSITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGTDiykDKESTVQVHYRMCQ 73
Cdd:cd07691  1 SVKENEDKVFLKCNsaSSITWKKGTEGIEASDKTDLDLGSRINDPRGTYQCKGSE---NKEKTLQVHYRMCQ 69
Ig_4 pfam16680
T-cell surface glycoprotein CD3 delta chain; This is an immunoglobulin-like domain. It is ...
 9-71 9.15e-24

T-cell surface glycoprotein CD3 delta chain; This is an immunoglobulin-like domain. It is found on the T-cell surface glycoprotein CD3 delta chain. CD3delta and CD3epsilon complex together as part of the T-cell receptor complex.


Pssm-ID: 465231  Cd Length: 63  Bit Score: 84.61  E-value: 9.15e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56967112    9 EDRVFVNCNT---SITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGtdiYKDKESTVQVHYRM 71
Cdd:pfam16680  1 DGKVLLTCNSsskSITWLKDGKGIKSTNTKTLDLGKFSEDPRGLYQCQG---EKKKSSTLQVYYRM 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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