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Conserved domains on  [gi|569002005|ref|XP_006525167|]
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UNC5C-like protein isoform X4 [Mus musculus]

Protein Classification

ZU5 and UPA domain-containing protein( domain architecture ID 12010079)

ZU5 and UPA domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZU5 pfam00791
ZU5 domain; Domain present in ZO-1 and Unc5-like netrin receptors Domain of unknown function.
 108-185 2.34e-28

ZU5 domain; Domain present in ZO-1 and Unc5-like netrin receptors Domain of unknown function.


:

Pssm-ID: 459941  Cd Length: 97  Bit Score: 106.84  E-value: 2.34e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 569002005  108 VDHRGGCLILQDTGISLLIPPGAVTVGRQERVSLVLVWDLTDAPSLSHRQGLVSPVVACGPHGASFLKPCTLTFKHCA 185
Cdd:pfam00791   5 VDSRGGRLVLPNSGVSLLIPPGAIPEGTRIECYLAVNRDESSRPPLEEGETLLSPVVECGPPGLKFLKPVILEVPHCA 82
UPA super family cl25437
UPA domain; The UPA domain is conserved in UNC5, PIDD, and Ankyrins. It has a beta sandwich ...
 243-346 1.00e-06

UPA domain; The UPA domain is conserved in UNC5, PIDD, and Ankyrins. It has a beta sandwich structure.


The actual alignment was detected with superfamily member pfam17217:

Pssm-ID: 465384  Cd Length: 140  Bit Score: 47.74  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569002005  243 ARKWLQLAMFcSPLVPGQTHLQLRVYFLNNTPCALQWAITNEQPHGGR-MRGPCQLFdFTGARADQCLKLKYISEG-WEN 320
Cdd:pfam17217   1 AIKRLRLAVF-APAACTSLEYSLRVYCLDDTPDALKEVVQLEKQLGGQlLEEPKTLH-FKDSTHNLRLSIHDIPPSlWKS 78

                          90       100
                  ....*....|....*....|....*.
gi 569002005  321 VDDSSSQLVPHLHIWHGKCPFRSFCF 346
Cdd:pfam17217  79 KLFAKYQEIPFYHVWSGNQNPLHCTF 104
 
Name Accession Description Interval E-value
ZU5 pfam00791
ZU5 domain; Domain present in ZO-1 and Unc5-like netrin receptors Domain of unknown function.
 108-185 2.34e-28

ZU5 domain; Domain present in ZO-1 and Unc5-like netrin receptors Domain of unknown function.


Pssm-ID: 459941  Cd Length: 97  Bit Score: 106.84  E-value: 2.34e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 569002005  108 VDHRGGCLILQDTGISLLIPPGAVTVGRQERVSLVLVWDLTDAPSLSHRQGLVSPVVACGPHGASFLKPCTLTFKHCA 185
Cdd:pfam00791   5 VDSRGGRLVLPNSGVSLLIPPGAIPEGTRIECYLAVNRDESSRPPLEEGETLLSPVVECGPPGLKFLKPVILEVPHCA 82
ZU5 smart00218
Domain present in ZO-1 and Unc5-like netrin receptors; Domain of unknown function.
 108-185 1.43e-19

Domain present in ZO-1 and Unc5-like netrin receptors; Domain of unknown function.


Pssm-ID: 128514  Cd Length: 104  Bit Score: 83.17  E-value: 1.43e-19
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 569002005   108 VDHRGGCLILQDTGISLLIPPGAVTVGRQERVSLVLVWDLTDAPSLSHRQGLVSPVVACGPHGASFLKPCTLTFKHCA 185
Cdd:smart00218   9 FDARGGRLRGPRTGVRLIIPPGAIPQGTRYTCYLVVHKTLSTPPPLEEGETLLSPVVECGPHGALFLRPVILEVPHCA 86
UPA pfam17217
UPA domain; The UPA domain is conserved in UNC5, PIDD, and Ankyrins. It has a beta sandwich ...
 243-346 1.00e-06

UPA domain; The UPA domain is conserved in UNC5, PIDD, and Ankyrins. It has a beta sandwich structure.


Pssm-ID: 465384  Cd Length: 140  Bit Score: 47.74  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569002005  243 ARKWLQLAMFcSPLVPGQTHLQLRVYFLNNTPCALQWAITNEQPHGGR-MRGPCQLFdFTGARADQCLKLKYISEG-WEN 320
Cdd:pfam17217   1 AIKRLRLAVF-APAACTSLEYSLRVYCLDDTPDALKEVVQLEKQLGGQlLEEPKTLH-FKDSTHNLRLSIHDIPPSlWKS 78

                          90       100
                  ....*....|....*....|....*.
gi 569002005  321 VDDSSSQLVPHLHIWHGKCPFRSFCF 346
Cdd:pfam17217  79 KLFAKYQEIPFYHVWSGNQNPLHCTF 104
 
Name Accession Description Interval E-value
ZU5 pfam00791
ZU5 domain; Domain present in ZO-1 and Unc5-like netrin receptors Domain of unknown function.
 108-185 2.34e-28

ZU5 domain; Domain present in ZO-1 and Unc5-like netrin receptors Domain of unknown function.


Pssm-ID: 459941  Cd Length: 97  Bit Score: 106.84  E-value: 2.34e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 569002005  108 VDHRGGCLILQDTGISLLIPPGAVTVGRQERVSLVLVWDLTDAPSLSHRQGLVSPVVACGPHGASFLKPCTLTFKHCA 185
Cdd:pfam00791   5 VDSRGGRLVLPNSGVSLLIPPGAIPEGTRIECYLAVNRDESSRPPLEEGETLLSPVVECGPPGLKFLKPVILEVPHCA 82
ZU5 smart00218
Domain present in ZO-1 and Unc5-like netrin receptors; Domain of unknown function.
 108-185 1.43e-19

Domain present in ZO-1 and Unc5-like netrin receptors; Domain of unknown function.


Pssm-ID: 128514  Cd Length: 104  Bit Score: 83.17  E-value: 1.43e-19
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 569002005   108 VDHRGGCLILQDTGISLLIPPGAVTVGRQERVSLVLVWDLTDAPSLSHRQGLVSPVVACGPHGASFLKPCTLTFKHCA 185
Cdd:smart00218   9 FDARGGRLRGPRTGVRLIIPPGAIPQGTRYTCYLVVHKTLSTPPPLEEGETLLSPVVECGPHGALFLRPVILEVPHCA 86
UPA pfam17217
UPA domain; The UPA domain is conserved in UNC5, PIDD, and Ankyrins. It has a beta sandwich ...
 243-346 1.00e-06

UPA domain; The UPA domain is conserved in UNC5, PIDD, and Ankyrins. It has a beta sandwich structure.


Pssm-ID: 465384  Cd Length: 140  Bit Score: 47.74  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569002005  243 ARKWLQLAMFcSPLVPGQTHLQLRVYFLNNTPCALQWAITNEQPHGGR-MRGPCQLFdFTGARADQCLKLKYISEG-WEN 320
Cdd:pfam17217   1 AIKRLRLAVF-APAACTSLEYSLRVYCLDDTPDALKEVVQLEKQLGGQlLEEPKTLH-FKDSTHNLRLSIHDIPPSlWKS 78

                          90       100
                  ....*....|....*....|....*.
gi 569002005  321 VDDSSSQLVPHLHIWHGKCPFRSFCF 346
Cdd:pfam17217  79 KLFAKYQEIPFYHVWSGNQNPLHCTF 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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