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Conserved domains on  [gi|566155488|ref|XP_006386119|]
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uncharacterized protein LOC7474534 isoform X1 [Populus trichocarpa]

Protein Classification

YjbQ family protein( domain architecture ID 10001434)

YjbQ family protein may have thiamin phosphate synthase activity

CATH:  2.60.120.460
PubMed:  18178222
SCOP:  4002602

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YjbQ COG0432
Thiamin phosphate synthase YjbQ, UPF0047 family [Coenzyme transport and metabolism];
48-149 3.35e-44

Thiamin phosphate synthase YjbQ, UPF0047 family [Coenzyme transport and metabolism];


:

Pssm-ID: 440201  Cd Length: 133  Bit Score: 143.67  E-value: 3.35e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 566155488  48 QKTITL-PPHRRGCHLITPKILNEIgsDLSEFKCGLAHLFLHHTSASLTINENYDSDVRDDTETFLNKIVPEGrsAPWKH 126
Cdd:COG0432    1 QEELTVeTTRRRGFIDITDEVEEAV--AESGIKEGLVHVFVPHTTASLTINENADPGVRRDLEAFLERLVPED--DPYRH 76

                         90       100
                 ....*....|....*....|...
gi 566155488 127 TLEGPDDMPAHIKSSMFGCSLTF 149
Cdd:COG0432   77 NLEGPDNMPAHLKASLLGSSLTI 99
 
Name Accession Description Interval E-value
YjbQ COG0432
Thiamin phosphate synthase YjbQ, UPF0047 family [Coenzyme transport and metabolism];
48-149 3.35e-44

Thiamin phosphate synthase YjbQ, UPF0047 family [Coenzyme transport and metabolism];


Pssm-ID: 440201  Cd Length: 133  Bit Score: 143.67  E-value: 3.35e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 566155488  48 QKTITL-PPHRRGCHLITPKILNEIgsDLSEFKCGLAHLFLHHTSASLTINENYDSDVRDDTETFLNKIVPEGrsAPWKH 126
Cdd:COG0432    1 QEELTVeTTRRRGFIDITDEVEEAV--AESGIKEGLVHVFVPHTTASLTINENADPGVRRDLEAFLERLVPED--DPYRH 76

                         90       100
                 ....*....|....*....|...
gi 566155488 127 TLEGPDDMPAHIKSSMFGCSLTF 149
Cdd:COG0432   77 NLEGPDNMPAHLKASLLGSSLTI 99
UPF0047 pfam01894
Uncharacterized protein family UPF0047; This family has no known function. The alignment ...
 62-149 5.86e-39

Uncharacterized protein family UPF0047; This family has no known function. The alignment contains a conserved aspartate and histidine that may be functionally important.


Pssm-ID: 460376  Cd Length: 116  Bit Score: 129.83  E-value: 5.86e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 566155488   62 LITPKILNEIgsDLSEFKCGLAHLFLHHTSASLTINENYDSDVRDDTETFLNKIVPEGRsaPWKHTLEGPDDMPAHIKSS 141
Cdd:pfam01894   1 DITDEVEEAV--AESGIKEGLVHVFVPHTTASLTINENADPDVRRDLEAFLERLVPEDD--PYRHNDEGPDNMPAHLKAS 76


                  ....*...
gi 566155488  142 MFGCSLTF 149
Cdd:pfam01894  77 LLGPSLTI 84
TIGR00149_YjbQ TIGR00149
secondary thiamine-phosphate synthase enzyme; Members of this protein family have been studied ...
 48-148 1.05e-27

secondary thiamine-phosphate synthase enzyme; Members of this protein family have been studied extensively by crystallography. Members from several different species have been shown to have sufficient thiamin phosphate synthase activity (EC 2.5.1.3) to complement thiE mutants. However, it is presumed that this is a secondary activity, and the primary function of this enzyme remains unknown. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 129253  Cd Length: 132  Bit Score: 101.37  E-value: 1.05e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 566155488   48 QKTITLPPHRRGCHLITPKILNEIGSdlSEFKCGLAHLFLHHTSASLTINENYDSDVRDDTETFLNKIVPEGRSapWKHT 127
Cdd:TIGR00149   1 QELLLKTTKRVELIDITSEIEAVLQS--SGVKDGLLLVYVPHTTASLTINENADPDVLHDIERFFERLVPDDGN--YEHD 76

                          90       100
                  ....*....|....*....|.
gi 566155488  128 lEGPDDMPAHIKSSMFGCSLT 148
Cdd:TIGR00149  77 -EGDDNMDAHIKSSLLGTSQH 96
 
Name Accession Description Interval E-value
YjbQ COG0432
Thiamin phosphate synthase YjbQ, UPF0047 family [Coenzyme transport and metabolism];
48-149 3.35e-44

Thiamin phosphate synthase YjbQ, UPF0047 family [Coenzyme transport and metabolism];


Pssm-ID: 440201  Cd Length: 133  Bit Score: 143.67  E-value: 3.35e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 566155488  48 QKTITL-PPHRRGCHLITPKILNEIgsDLSEFKCGLAHLFLHHTSASLTINENYDSDVRDDTETFLNKIVPEGrsAPWKH 126
Cdd:COG0432    1 QEELTVeTTRRRGFIDITDEVEEAV--AESGIKEGLVHVFVPHTTASLTINENADPGVRRDLEAFLERLVPED--DPYRH 76

                         90       100
                 ....*....|....*....|...
gi 566155488 127 TLEGPDDMPAHIKSSMFGCSLTF 149
Cdd:COG0432   77 NLEGPDNMPAHLKASLLGSSLTI 99
UPF0047 pfam01894
Uncharacterized protein family UPF0047; This family has no known function. The alignment ...
 62-149 5.86e-39

Uncharacterized protein family UPF0047; This family has no known function. The alignment contains a conserved aspartate and histidine that may be functionally important.


Pssm-ID: 460376  Cd Length: 116  Bit Score: 129.83  E-value: 5.86e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 566155488   62 LITPKILNEIgsDLSEFKCGLAHLFLHHTSASLTINENYDSDVRDDTETFLNKIVPEGRsaPWKHTLEGPDDMPAHIKSS 141
Cdd:pfam01894   1 DITDEVEEAV--AESGIKEGLVHVFVPHTTASLTINENADPDVRRDLEAFLERLVPEDD--PYRHNDEGPDNMPAHLKAS 76


                  ....*...
gi 566155488  142 MFGCSLTF 149
Cdd:pfam01894  77 LLGPSLTI 84
TIGR00149_YjbQ TIGR00149
secondary thiamine-phosphate synthase enzyme; Members of this protein family have been studied ...
 48-148 1.05e-27

secondary thiamine-phosphate synthase enzyme; Members of this protein family have been studied extensively by crystallography. Members from several different species have been shown to have sufficient thiamin phosphate synthase activity (EC 2.5.1.3) to complement thiE mutants. However, it is presumed that this is a secondary activity, and the primary function of this enzyme remains unknown. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 129253  Cd Length: 132  Bit Score: 101.37  E-value: 1.05e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 566155488   48 QKTITLPPHRRGCHLITPKILNEIGSdlSEFKCGLAHLFLHHTSASLTINENYDSDVRDDTETFLNKIVPEGRSapWKHT 127
Cdd:TIGR00149   1 QELLLKTTKRVELIDITSEIEAVLQS--SGVKDGLLLVYVPHTTASLTINENADPDVLHDIERFFERLVPDDGN--YEHD 76

                          90       100
                  ....*....|....*....|.
gi 566155488  128 lEGPDDMPAHIKSSMFGCSLT 148
Cdd:TIGR00149  77 -EGDDNMDAHIKSSLLGTSQH 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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