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Conserved domains on  [gi|56117844|ref|NP_005628|]
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protein SSXT isoform 2 [Homo sapiens]

Protein Classification

SS18 family protein( domain architecture ID 10523487)

SS18 family protein similar to human calcium-responsive transactivator (also called SS18-like protein 1) that is required for calcium-dependent dendritic growth and branching in cortical neurons

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SSXT pfam05030
SSXT protein (N-terminal region); The SSXT or SS18 protein is involved in synovial sarcoma in ...
 14-73 5.59e-26

SSXT protein (N-terminal region); The SSXT or SS18 protein is involved in synovial sarcoma in humans. A SYT-SSX fusion gene resulting from the chromosomal translocation t(X;18) (p11;q11) is characteriztic of synovial sarcomas. This translocation fuses the SSXT (SYT) gene from chromosome 18 to either of two homologous genes at Xp11, SSX1 or SSX2.


:

Pssm-ID: 428268  Cd Length: 60  Bit Score: 98.88  E-value: 5.59e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 56117844    14 GEITPAAIQKMLDDNNHLIQCIMDSQNKGKTSECSQYQQMLHTNLVYLATIADSNQNMQS 73
Cdd:pfam05030   1 PPPNQEQIQKMLDENSQLIQCIQEYQNKGRAQECMQYQQILHRNLVYLATIADSNQNIQQ 60
 
Name Accession Description Interval E-value
SSXT pfam05030
SSXT protein (N-terminal region); The SSXT or SS18 protein is involved in synovial sarcoma in ...
 14-73 5.59e-26

SSXT protein (N-terminal region); The SSXT or SS18 protein is involved in synovial sarcoma in humans. A SYT-SSX fusion gene resulting from the chromosomal translocation t(X;18) (p11;q11) is characteriztic of synovial sarcomas. This translocation fuses the SSXT (SYT) gene from chromosome 18 to either of two homologous genes at Xp11, SSX1 or SSX2.


Pssm-ID: 428268  Cd Length: 60  Bit Score: 98.88  E-value: 5.59e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 56117844    14 GEITPAAIQKMLDDNNHLIQCIMDSQNKGKTSECSQYQQMLHTNLVYLATIADSNQNMQS 73
Cdd:pfam05030   1 PPPNQEQIQKMLDENSQLIQCIQEYQNKGRAQECMQYQQILHRNLVYLATIADSNQNIQQ 60
 
Name Accession Description Interval E-value
SSXT pfam05030
SSXT protein (N-terminal region); The SSXT or SS18 protein is involved in synovial sarcoma in ...
 14-73 5.59e-26

SSXT protein (N-terminal region); The SSXT or SS18 protein is involved in synovial sarcoma in humans. A SYT-SSX fusion gene resulting from the chromosomal translocation t(X;18) (p11;q11) is characteriztic of synovial sarcomas. This translocation fuses the SSXT (SYT) gene from chromosome 18 to either of two homologous genes at Xp11, SSX1 or SSX2.


Pssm-ID: 428268  Cd Length: 60  Bit Score: 98.88  E-value: 5.59e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 56117844    14 GEITPAAIQKMLDDNNHLIQCIMDSQNKGKTSECSQYQQMLHTNLVYLATIADSNQNMQS 73
Cdd:pfam05030   1 PPPNQEQIQKMLDENSQLIQCIQEYQNKGRAQECMQYQQILHRNLVYLATIADSNQNIQQ 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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