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Conserved domains on  [gi|55770834|ref|NP_057427|]
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centromere protein F [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CENP-F_N pfam10481
Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound ...
 1-307 8.76e-136

Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound across the centromere as one of the proteins of the outer layer of the kinetochore. Most of the kinetochore/centromere functions appear to depend upon binding of the C-terminal par to f the molecule, whereas the N-terminal part, here, may be a cytoplasmic player in controlling the function of microtubules and dynein.


:

Pssm-ID: 463106 [Multi-domain]  Cd Length: 304  Bit Score: 427.32  E-value: 8.76e-136
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834      1 MSWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLE 80
Cdd:pfam10481    1 MSWAVEEWKEGLPTKALQKIQELESQLDKLKKERQQKQFQLESLEAALQKQKQKVENEKNEGSALKRENQSLMESCDNLE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     81 KTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYS 160
Cdd:pfam10481   81 KSRQKISHDLQVKESQVNFLEGQLNSSKKQIEKLEQELKRYKSELERSQQALLAGDVSLQPCSTPQKSFATPLTPSQRHN 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    161 GSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRD 240
Cdd:pfam10481  161 DSKYEELQEKYNKEVEERKRLEAELKVLQVKKTNQTLPQSTVSHRDIARHQASSSVFPWQQEKTPSRQSSDAQETPLKRG 240

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834    241 FSASYFSGEQEVTPSRSTLqigKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKE 307
Cdd:pfam10481  241 FTASHFLWEHEETPSKRSQ---RSSSNSSLQSNSSSSQLMDQLKAQNQELRSRVSELELRLQAQEKD 304
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2131-2270 1.87e-42

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


:

Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 152.84  E-value: 1.87e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2131 DEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2211 EKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNE 2270
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2313-2452 4.62e-41

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


:

Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 148.98  E-value: 4.62e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2313 DEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRS 2392
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2393 EKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNE 2452
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1983-2758 3.43e-28

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 125.17  E-value: 3.43e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1983 KMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLN 2062
Cdd:TIGR02168  233 RLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2063 KEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKL 2142
Cdd:TIGR02168  309 ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2143 KERERENDSLKDKVENLERELQMSEENQElvILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEK 2222
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRE--RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2223 QGQLSELDKLLSSFKSLLEEKEQaeiqikeeSKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 2302
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQA--------RLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2303 IEK-LRARLEA----DEKKQLCVLQQLKESEhhadllKGRVENLERELEIARTNQEHAALEAENSKG------EVETLKA 2371
Cdd:TIGR02168  539 IEAaLGGRLQAvvveNLNAAKKAIAFLKQNE------LGRVTFLPLDSIKGTEIQGNDREILKNIEGflgvakDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2372 KIEGMTQSLRGLELDVVTIRSekenlTNELQKE---QERISEL--EIINSSFeNILQEKEQEKVQMKEKSStAMEMLQTQ 2446
Cdd:TIGR02168  613 KLRKALSYLLGGVLVVDDLDN-----ALELAKKlrpGYRIVTLdgDLVRPGG-VITGGSAKTNSSILERRR-EIEELEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2447 LKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISR 2526
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2527 LKNQIqdqEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMS 2606
Cdd:TIGR02168  766 LEERL---EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2607 FVEKVNKMTAKETELQREMHEMAQKTAELQEEL---SGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDcmhk 2683
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELealLNERASLEEALALLRSELEELSEELRELESKRSELRRELE---- 918

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55770834   2684 dqvekegKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNN 2758
Cdd:TIGR02168  919 -------ELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP 986
CENP-F_C_Rb_bdg pfam10490
Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2967-3013 4.00e-20

Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. This domain is at the very C-terminus of the C-terminal coiled-coil, and is one of the key Rb-binding domains.


:

Pssm-ID: 463111  Cd Length: 47  Bit Score: 85.58  E-value: 4.00e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 55770834   2967 PAEDTEGTEFEPEGLPEVVKKGFADIPTGKTSPYILRRTTMATRTSP 3013
Cdd:pfam10490    1 NRAEQDDEEFEPEGLPEVVQKGFADIPSGEVSPYILRRTTLQLRCSP 47
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 316-1160 6.74e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.56  E-value: 6.74e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    316 QELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQAsTKYTALEQKLKKLTEDLSCQRQNAESARcsleqkiKEKEKE 395
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKA-ERYKELKAELRELELALLVLRLEELREE-------LEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    396 FQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKEN 475
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    476 ELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLnqsqnfaEEMKAKNTSQETMLRDLQEKINQQENSLTLEK 555
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL-------EELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    556 LKLAVADLEKQRdcSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEyeelkeektlfscwksENEKLLTQMES 635
Cdd:TIGR02168  400 NEIERLEARLER--LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE----------------ELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    636 EKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLaymeLQQKAEFsDQKHQ 715
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV----LSELISV-DEGYE 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    716 KEIENMCLKTSQLTgQVEDLEHKLQ----LLSNEIMDKDRCYQDLHAEYE---SLRDLLKSKD------ASLVTNEDHQR 782
Cdd:TIGR02168  537 AAIEAALGGRLQAV-VVENLNAAKKaiafLKQNELGRVTFLPLDSIKGTEiqgNDREILKNIEgflgvaKDLVKFDPKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    783 SLLAF---------------DQQPAMHHSFANI------IGEQGSM--------------PSERSECRLEADQSPKNSAI 827
Cdd:TIGR02168  616 KALSYllggvlvvddldnalELAKKLRPGYRIVtldgdlVRPGGVItggsaktnssilerRREIEELEEKIEELEEKIAE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFvaetSQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL----EERIAQLSKELTELEAEIEELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    988 QEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEEtgnaYEDLSQKYKAAQEKNSKLECLLNECTSLCENR 1067
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE----LEELSEELRELESKRSELRRELEELREKLAQL 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1068 KNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDnQNNSKSEAGGLK----QEIMTLKEEQNKMQ 1143
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNlaaiEEYEELKERYDFLT 1006

                          890
                   ....*....|....*..
gi 55770834   1144 KEVNDLLQENEQLMKVM 1160
Cdd:TIGR02168 1007 AQKEDLTEAKETLEEAI 1023
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2623-2930 1.44e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 1.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2623 REMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLdcmhKDQVEKEGKVREEIAEYQLR 2702
Cdd:COG1196  235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEER 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2703 LHEAEKKHQALlldtnkqyEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVN 2782
Cdd:COG1196  311 RRELEERLEEL--------EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2783 QLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQktgtvmDTKVDELTTEIKELKETLEEKTKEADEYLD 2862
Cdd:COG1196  383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL------EEALAELEEEEEEEEEALEEAAEEEAELEE 456

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 55770834 2863 KYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPLLGPVVPGPSPIPSVTEKRLSSGQNKASG 2930
Cdd:COG1196  457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524
PRK02224 super family cl32023
DNA double-strand break repair Rad50 ATPase;
1766-2194 1.34e-05

DNA double-strand break repair Rad50 ATPase;


The actual alignment was detected with superfamily member PRK02224:

Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 1.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1766 QEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1846 LEyfscdhqellqrvetseglnsDLEMHadkssREDIGDNVAKVNDSWKERFLDVENELSRIRsekasiEHEALyleadl 1925
Cdd:PRK02224  407 LG---------------------NAEDF-----LEELREERDELREREAELEATLRTARERVE------EAEAL------ 448

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1926 evvQTEKLCLEKDNENKQKVIVCL----EEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEkTQELESHQSECLHC 2001
Cdd:PRK02224  449 ---LEAGKCPECGQPVEGSPHVETieedRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR-IERLEERREDLEEL 524

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS- 2080
Cdd:PRK02224  525 IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADa 604

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2081 ESDYEKLNVSKALEAALVEkgEFALRLSSTQEEVHQLRRG-----IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDK 2155
Cdd:PRK02224  605 EDEIERLREKREALAELND--ERRERLAEKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREERDDLQAE 682

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 55770834  2156 VENLERELQMSEENQELviLDA-ENSKAEVETLKTQIEEM 2194
Cdd:PRK02224  683 IGAVENELEELEELRER--REAlENRVEALEALYDEAEEL 720
 
Name Accession Description Interval E-value
CENP-F_N pfam10481
Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound ...
 1-307 8.76e-136

Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound across the centromere as one of the proteins of the outer layer of the kinetochore. Most of the kinetochore/centromere functions appear to depend upon binding of the C-terminal par to f the molecule, whereas the N-terminal part, here, may be a cytoplasmic player in controlling the function of microtubules and dynein.


Pssm-ID: 463106 [Multi-domain]  Cd Length: 304  Bit Score: 427.32  E-value: 8.76e-136
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834      1 MSWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLE 80
Cdd:pfam10481    1 MSWAVEEWKEGLPTKALQKIQELESQLDKLKKERQQKQFQLESLEAALQKQKQKVENEKNEGSALKRENQSLMESCDNLE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     81 KTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYS 160
Cdd:pfam10481   81 KSRQKISHDLQVKESQVNFLEGQLNSSKKQIEKLEQELKRYKSELERSQQALLAGDVSLQPCSTPQKSFATPLTPSQRHN 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    161 GSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRD 240
Cdd:pfam10481  161 DSKYEELQEKYNKEVEERKRLEAELKVLQVKKTNQTLPQSTVSHRDIARHQASSSVFPWQQEKTPSRQSSDAQETPLKRG 240

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834    241 FSASYFSGEQEVTPSRSTLqigKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKE 307
Cdd:pfam10481  241 FTASHFLWEHEETPSKRSQ---RSSSNSSLQSNSSSSQLMDQLKAQNQELRSRVSELELRLQAQEKD 304
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2131-2270 1.87e-42

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 152.84  E-value: 1.87e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2131 DEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2211 EKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNE 2270
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2313-2452 4.62e-41

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 148.98  E-value: 4.62e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2313 DEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRS 2392
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2393 EKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNE 2452
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1983-2758 3.43e-28

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 125.17  E-value: 3.43e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1983 KMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLN 2062
Cdd:TIGR02168  233 RLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2063 KEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKL 2142
Cdd:TIGR02168  309 ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2143 KERERENDSLKDKVENLERELQMSEENQElvILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEK 2222
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRE--RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2223 QGQLSELDKLLSSFKSLLEEKEQaeiqikeeSKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 2302
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQA--------RLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2303 IEK-LRARLEA----DEKKQLCVLQQLKESEhhadllKGRVENLERELEIARTNQEHAALEAENSKG------EVETLKA 2371
Cdd:TIGR02168  539 IEAaLGGRLQAvvveNLNAAKKAIAFLKQNE------LGRVTFLPLDSIKGTEIQGNDREILKNIEGflgvakDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2372 KIEGMTQSLRGLELDVVTIRSekenlTNELQKE---QERISEL--EIINSSFeNILQEKEQEKVQMKEKSStAMEMLQTQ 2446
Cdd:TIGR02168  613 KLRKALSYLLGGVLVVDDLDN-----ALELAKKlrpGYRIVTLdgDLVRPGG-VITGGSAKTNSSILERRR-EIEELEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2447 LKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISR 2526
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2527 LKNQIqdqEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMS 2606
Cdd:TIGR02168  766 LEERL---EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2607 FVEKVNKMTAKETELQREMHEMAQKTAELQEEL---SGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDcmhk 2683
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELealLNERASLEEALALLRSELEELSEELRELESKRSELRRELE---- 918

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55770834   2684 dqvekegKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNN 2758
Cdd:TIGR02168  919 -------ELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP 986
CENP-F_C_Rb_bdg pfam10490
Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2967-3013 4.00e-20

Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. This domain is at the very C-terminus of the C-terminal coiled-coil, and is one of the key Rb-binding domains.


Pssm-ID: 463111  Cd Length: 47  Bit Score: 85.58  E-value: 4.00e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 55770834   2967 PAEDTEGTEFEPEGLPEVVKKGFADIPTGKTSPYILRRTTMATRTSP 3013
Cdd:pfam10490    1 NRAEQDDEEFEPEGLPEVVQKGFADIPSGEVSPYILRRTTLQLRCSP 47
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1977-2519 5.28e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.47  E-value: 5.28e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1977 LDQLSEKMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELEN 2056
Cdd:COG1196  241 LEELEAELEELEAELEELEAE----LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2057 QIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQL 2136
Cdd:COG1196  317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA 396

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2137 HIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLT 2216
Cdd:COG1196  397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2217 KQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEE 2296
Cdd:COG1196  477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2297 HQLRNSIEKLRARLEAdeKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGM 2376
Cdd:COG1196  557 EVAAAAIEYLKAAKAG--RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2377 TQSL-RGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVA 2455
Cdd:COG1196  635 ALRRaVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 55770834 2456 ALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEK 2519
Cdd:COG1196  715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2053-2603 6.10e-20

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 97.80  E-value: 6.10e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2053 ELENQIAQlnKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSS---TQEEVHQLRRGIEKLRVRIE 2129
Cdd:PRK02224  191 QLKAQIEE--KEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEheeRREELETLEAEIEDLRETIA 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2130 ADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Cdd:PRK02224  269 ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQN---QLKELNEAVAALCGDQEIMKATE 2286
Cdd:PRK02224  349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDapvDLGNAEDFLEELREERDELRERE 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2287 QSLDPPIEEehqLRNSIEKLRARLEADeKKQLCVlQQLKESEH--HADLLKGRVENLERELEIARTnqehaaleaenskg 2364
Cdd:PRK02224  429 AELEATLRT---ARERVEEAEALLEAG-KCPECG-QPVEGSPHveTIEEDRERVEELEAELEDLEE-------------- 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2365 EVETLKAKIEGMTqSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEmlq 2444
Cdd:PRK02224  490 EVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEE--- 565

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2445 tQLKELNERVAALHNDQEACKAKEQNLSSQVECLEL--EKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDE 2522
Cdd:PRK02224  566 -EAEEAREEVAELNSKLAELKERIESLERIRTLLAAiaDAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFD 644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2523 EiSRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQS---KNASLQDTLEVLQSSYKNLEnELEL 2599
Cdd:PRK02224  645 E-ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEElreRREALENRVEALEALYDEAE-ELES 722


                  ....
gi 55770834  2600 TKMD 2603
Cdd:PRK02224  723 MYGD 726
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 316-1160 6.74e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.56  E-value: 6.74e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    316 QELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQAsTKYTALEQKLKKLTEDLSCQRQNAESARcsleqkiKEKEKE 395
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKA-ERYKELKAELRELELALLVLRLEELREE-------LEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    396 FQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKEN 475
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    476 ELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLnqsqnfaEEMKAKNTSQETMLRDLQEKINQQENSLTLEK 555
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL-------EELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    556 LKLAVADLEKQRdcSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEyeelkeektlfscwksENEKLLTQMES 635
Cdd:TIGR02168  400 NEIERLEARLER--LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE----------------ELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    636 EKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLaymeLQQKAEFsDQKHQ 715
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV----LSELISV-DEGYE 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    716 KEIENMCLKTSQLTgQVEDLEHKLQ----LLSNEIMDKDRCYQDLHAEYE---SLRDLLKSKD------ASLVTNEDHQR 782
Cdd:TIGR02168  537 AAIEAALGGRLQAV-VVENLNAAKKaiafLKQNELGRVTFLPLDSIKGTEiqgNDREILKNIEgflgvaKDLVKFDPKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    783 SLLAF---------------DQQPAMHHSFANI------IGEQGSM--------------PSERSECRLEADQSPKNSAI 827
Cdd:TIGR02168  616 KALSYllggvlvvddldnalELAKKLRPGYRIVtldgdlVRPGGVItggsaktnssilerRREIEELEEKIEELEEKIAE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFvaetSQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL----EERIAQLSKELTELEAEIEELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    988 QEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEEtgnaYEDLSQKYKAAQEKNSKLECLLNECTSLCENR 1067
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE----LEELSEELRELESKRSELRRELEELREKLAQL 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1068 KNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDnQNNSKSEAGGLK----QEIMTLKEEQNKMQ 1143
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNlaaiEEYEELKERYDFLT 1006

                          890
                   ....*....|....*..
gi 55770834   1144 KEVNDLLQENEQLMKVM 1160
Cdd:TIGR02168 1007 AQKEDLTEAKETLEEAI 1023
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2129-2896 3.04e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.53  E-value: 3.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2129 EADEKKQLHIAEKLKERERENdslKDKVENLERElqmsEENQELVILDAENSKAEVETLKTQIEEMARSLKVfeLDLVTL 2208
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETEN---LAELIIDLEE----LKLQELKLKEQAKKALEYYQLKEKLELEEEYLLY--LDYLKL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2209 RSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVaalcgdQEIMKATEQS 2288
Cdd:pfam02463  235 NEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEEL------KSELLKLERR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2289 LDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAensKGEVET 2368
Cdd:pfam02463  309 KVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKK---KLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2369 LKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLK 2448
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2449 ELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLK 2528
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2529 NQIQDQEQLVSKLSQVEGEHqlwKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKmSFV 2608
Cdd:pfam02463  546 STAVIVEVSATADEVEERQK---LVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADED-DKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2609 EKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEK 2688
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2689 EGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILE 2768
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2769 ELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKE 2848
Cdd:pfam02463  782 KTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEE 861

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 55770834   2849 TLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQD 2896
Cdd:pfam02463  862 EITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKL 909
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 288-568 1.10e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  288 QELRNKINELELRLQGH-----EKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ 362
Cdd:COG1196  216 RELKEELKELEAELLLLklrelEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  363 KLKKLTEDLSCQRQNAESARcsleqKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKL 442
Cdd:COG1196  296 ELARLEQDIARLEERRRELE-----ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  443 TSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNF 522
Cdd:COG1196  371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 55770834  523 AEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRD 568
Cdd:COG1196  451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 360-588 5.49e-08

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 58.71  E-value: 5.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    360 LEQKLKKLTEDLSCQRQNAESAR--CSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQaknMHNVLQA 437
Cdd:pfam09726  400 LEQDIKKLKAELQASRQTEQELRsqISSLTSLERSLKSELGQLRQENDLLQTKLHNAVSAKQKDKQTVQQ---LEKRLKA 476

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    438 ELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENE----LRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIK 513
Cdd:pfam09726  477 EQEARASAEKQLAEEKKRKKEEEATAARAVALAAASRGEctesLKQRKRELESEIKKLTHDIKLKEEQIRELEIKVQELR 556

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    514 QCLNQSQNFAEEMKAkntsqetmLRDLQEKINQQENSLTLE-KLKL----AVADLEKQRDCSQDLLKKREHHIEQLNDKL 588
Cdd:pfam09726  557 KYKESEKDTEVLMSA--------LSAMQDKNQHLENSLSAEtRIKLdlfsALGDAKRQLEIAQGQIYQKDQEIKDLKQKI 628
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2623-2930 1.44e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 1.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2623 REMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLdcmhKDQVEKEGKVREEIAEYQLR 2702
Cdd:COG1196  235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEER 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2703 LHEAEKKHQALlldtnkqyEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVN 2782
Cdd:COG1196  311 RRELEERLEEL--------EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2783 QLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQktgtvmDTKVDELTTEIKELKETLEEKTKEADEYLD 2862
Cdd:COG1196  383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL------EEALAELEEEEEEEEEALEEAAEEEAELEE 456

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 55770834 2863 KYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPLLGPVVPGPSPIPSVTEKRLSSGQNKASG 2930
Cdd:COG1196  457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2034-2275 2.01e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 2.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2034 QEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQaRLSESDYEKLNVsKALEAALVEKGEFALRLSSTQEE 2113
Cdd:COG4913  609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQ-RLAEYSWDEIDV-ASAEREIAELEAELERLDASSDD 686

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2114 VHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQ-MSEENQELVILDAENSKAEvETLKTQIE 2192
Cdd:COG4913  687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEaAEDLARLELRALLEERFAA-ALGDAVER 765

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2193 EMARSLkvfELDLVTLRSEKENLTKQIQEKQGQ----------------------LSELDKLLSS--------FKSLLEE 2242
Cdd:COG4913  766 ELRENL---EERIDALRARLNRAEEELERAMRAfnrewpaetadldadleslpeyLALLDRLEEDglpeyeerFKELLNE 842

                        250       260       270
                 ....*....|....*....|....*....|....
gi 55770834 2243 KEQAEI-QIKEESKTAVEMLQNQLKELNEAVAAL 2275
Cdd:COG4913  843 NSIEFVaDLLSKLRRAIREIKERIDPLNDSLKRI 876
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 20-362 1.06e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 1.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   20 IQELEGQLDKLKKEKQQ-----------RQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISH 88
Cdd:COG1196  195 LGELERQLEPLERQAEKaeryrelkeelKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   89 ELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLnpcntpqkifttpltpsqyysgskyEDLK 168
Cdd:COG1196  275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL-------------------------AELE 329

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  169 EKYNKEVEERKRLEAEVKALQAKKASQtlpQATMNHRDIARHQASSSVFSWQQEktpshlssnsqrtpiRRDFSASYFSG 248
Cdd:COG1196  330 EELEELEEELEELEEELEEAEEELEEA---EAELAEAEEALLEAEAELAEAEEE---------------LEELAEELLEA 391

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  249 EQEVTPSRSTLQIGKRDANSSFFdnsssphLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVE 328
Cdd:COG1196  392 LRAAAELAAQLEELEEAEEALLE-------RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                        330       340       350
                 ....*....|....*....|....*....|....
gi 55770834  329 LIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ 362
Cdd:COG1196  465 LAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2271-2484 5.79e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 5.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2271 AVAALCGDQEIMKATEQSLDppieeehQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL----- 2345
Cdd:COG4942   11 LALAAAAQADAAAEAEAELE-------QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELaalea 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2346 EIARTNQEHAALEAE-----------------NSKGEVETLKAKIEGMTQSLRGLELdVVTIRSEKENLTNELQKEQERI 2408
Cdd:COG4942   84 ELAELEKEIAELRAEleaqkeelaellralyrLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAEL 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 55770834 2409 SELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQ 2484
Cdd:COG4942  163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
809-1235 6.64e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.99  E-value: 6.64e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   809 SERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQsfVAETSQRISKL 888
Cdd:PRK03918  238 EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEE--YLDELREIEKR 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   889 QEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLkelQLLSETLSLEKKEMSSIISLNKRE 968
Cdd:PRK03918  316 LSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK---AKKEELERLKKRLTGLTPEKLEKE 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   969 IEELTQENGTLKEINASLNQEKMNLIQKsesfanyIDEREKSISELSdqyKQEKLILLQRCEETGNAYEDLSQKYKAaqe 1048
Cdd:PRK03918  393 LEELEKAKEEIEEEISKITARIGELKKE-------IKELKKAIEELK---KAKGKCPVCGRELTEEHRKELLEEYTA--- 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1049 KNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQefLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGL 1128
Cdd:PRK03918  460 ELKRIEKELKEIEEKERKLRKELRELEKVLKKESE--LIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKL 537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1129 KQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCN---------FKPQMDLEVK 1199
Cdd:PRK03918  538 KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEpfyneylelKDAEKELERE 617

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 55770834  1200 EISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQ 1235
Cdd:PRK03918  618 EKELKKLEEELDKAFEELAETEKRLEELRKELEELE 653
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1766-2194 1.34e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 1.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1766 QEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1846 LEyfscdhqellqrvetseglnsDLEMHadkssREDIGDNVAKVNDSWKERFLDVENELSRIRsekasiEHEALyleadl 1925
Cdd:PRK02224  407 LG---------------------NAEDF-----LEELREERDELREREAELEATLRTARERVE------EAEAL------ 448

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1926 evvQTEKLCLEKDNENKQKVIVCL----EEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEkTQELESHQSECLHC 2001
Cdd:PRK02224  449 ---LEAGKCPECGQPVEGSPHVETieedRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR-IERLEERREDLEEL 524

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS- 2080
Cdd:PRK02224  525 IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADa 604

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2081 ESDYEKLNVSKALEAALVEkgEFALRLSSTQEEVHQLRRG-----IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDK 2155
Cdd:PRK02224  605 EDEIERLREKREALAELND--ERRERLAEKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREERDDLQAE 682

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 55770834  2156 VENLERELQMSEENQELviLDA-ENSKAEVETLKTQIEEM 2194
Cdd:PRK02224  683 IGAVENELEELEELRER--REAlENRVEALEALYDEAEEL 720
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 1893-2018 8.08e-05

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 44.98  E-value: 8.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1893 WKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSK 1972
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 55770834   1973 KTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQT 2018
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKT 126
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 18-371 8.29e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 8.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKESQV 97
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     98 NFQEGQLNSGKKQIEKLEQELKRCKSELERSQQaaqsadvslnpcntpqkifttpltpsqyysgsKYEDLKEKYNKEVEE 177
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEA--------------------------------QIEQLKEELKALREA 804

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    178 RKRLEAEVKALQAKKASQTLPQAtMNHRDIARHQASSSVFSWQQEKTPSHLSSNsqrtpirrdfSASYFSGEQEVTPSRS 257
Cdd:TIGR02168  805 LDELRAELTLLNEEAANLRERLE-SLERRIAATERRLEDLEEQIEELSEDIESL----------AAEIEELEELIEELES 873

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    258 TLQigkrdanSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIE-KEKVL 336
Cdd:TIGR02168  874 ELE-------ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNlQERLS 946

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 55770834    337 NKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDL 371
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1765-2094 1.12e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1765 NQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSE 1844
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1845 KLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREdigdnvakvNDSWKERFLDVENELSRIRSEKASiehealyLEAD 1924
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE---------LKALREALDELRAELTLLNEEAAN-------LRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1925 LEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQV 2004
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2005 AEAEVKEKTELLQ-------TLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTK--------CELENQIAQLNKEKELL- 2068
Cdd:TIGR02168  906 LESKRSELRRELEelreklaQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALenkieddeEEARRRLKRLENKIKELg 985

                          330       340       350
                   ....*....|....*....|....*....|..
gi 55770834   2069 ------VKESESLQARLSESDYEKLNVSKALE 2094
Cdd:TIGR02168  986 pvnlaaIEEYEELKERYDFLTAQKEDLTEAKE 1017
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2634-2883 2.00e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.23  E-value: 2.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2634 ELQEELSGEKNRLAGELqllLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEyqlrlhEAEKkhqal 2713
Cdd:PRK05771   35 DLKEELSNERLRKLRSL---LTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELE------KIEK----- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2714 lldtnkqyEV-EIQTYREKLTSKEECLSSQKLEIDLLK--SSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENER 2790
Cdd:PRK05771  101 --------EIkELEEEISELENEIKELEQEIERLEPWGnfDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYI 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2791 AQGKMK---LLIKSCKQLEEEKEILQK-ELSQLQAAQEkqktGTVMD------TKVDELTTEIKELKETLEEKTKE-ADE 2859
Cdd:PRK05771  173 STDKGYvyvVVVVLKELSDEVEEELKKlGFERLELEEE----GTPSElireikEELEEIEKERESLLEELKELAKKyLEE 248

                         250       260
                  ....*....|....*....|....
gi 55770834  2860 YLDKYCSLLISHEKLEKAKEMLET 2883
Cdd:PRK05771  249 LLALYEYLEIELERAEALSKFLKT 272
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2654-2900 2.31e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2654 LEEIKSSKDQLKELTLENSELKksldcmhkDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLT 2733
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKR--------QQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2734 SKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKY-VNQLKKENERAQGKMKLLIKSCKQLEEEKEIL 2812
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEkIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2813 QKELSQLQAAQEKQKTG-TVMDTKVDELTTEIKELKET-------LEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQ 2884
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREiEEERKRRDKLTEEYAELKEEledlraeLEEVDKEFAETRDELKDYREKLEKLKREINELKRE 407

                          250
                   ....*....|....*.
gi 55770834   2885 VAHLCSQQSKQDSRGS 2900
Cdd:TIGR02169  408 LDRLQEELQRLSEELA 423
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2191-2441 2.74e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.46  E-value: 2.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2191 IEEMARslkvfeLDLVTLRSEKENLTKQIQE----------KQGQ----------LSELDKLLSSFKSLLEEkeqAEIQI 2250
Cdd:PRK05771    3 PVRMKK------VLIVTLKSYKDEVLEALHElgvvhiedlkEELSnerlrklrslLTKLSEALDKLRSYLPK---LNPLR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2251 KEESKTAVEMLQNQLKELNEAVAALcgdqeimkatEQSLDPPIEEEHQLRNSIEKLRARLEADEK-KQLCVLQQLKESEH 2329
Cdd:PRK05771   74 EEKKKVSVKSLEELIKDVEEELEKI----------EKEIKELEEEISELENEIKELEQEIERLEPwGNFDLDLSLLLGFK 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2330 HADLLKGRVeNLERELEIARTNQEHAALEAENSKGE----VETLKAKIEGMTQSLRGLELDVVTIrSEKENLTNELQKEQ 2405
Cdd:PRK05771  144 YVSVFVGTV-PEDKLEELKLESDVENVEYISTDKGYvyvvVVVLKELSDEVEEELKKLGFERLEL-EEEGTPSELIREIK 221

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 55770834  2406 ERI----SELEIINSSFENILQEKEQEKVQMKEKSSTAME 2441
Cdd:PRK05771  222 EELeeieKERESLLEELKELAKKYLEELLALYEYLEIELE 261
Leu_zip pfam15294
Leucine zipper; This family includes Leucine zipper transcription factor-like protein 1 ...
 2779-2885 3.81e-03

Leucine zipper; This family includes Leucine zipper transcription factor-like protein 1 (LZTFL1) and Leucine zipper protein 2 (LUZP2).


Pssm-ID: 464620 [Multi-domain]  Cd Length: 276  Bit Score: 42.00  E-value: 3.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2779 KYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELK----ETLEEKT 2854
Cdd:pfam15294  133 MEIERLKEENEKLKERLKTLESQATQALDEKSKLEKALKDLQKEQGAKKDVKSNLKEISDLEEKMAALKsdleKTLNAST 212

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 55770834   2855 KEADEYLDKYCS----LLISHEKLEKAKEMLETQV 2885
Cdd:pfam15294  213 ALQKSLEEDLAStkheLLKVQEQLEMAEKELEKKF 247
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 2579-2732 7.05e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.54  E-value: 7.05e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    2579 LQDTLEVLQSSYKNLENELELTKmdkmsfvEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIK 2658
Cdd:smart00787  149 LDENLEGLKEDYKLLMKELELLN-------SIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAKEKLKKLLQEIM 221

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55770834    2659 SSKDQLKELTLENSELKKSLDcmhkdqvekegKVREEIAEYQLRLHEAEKKhqallLDTNKQYEV-EIQTYREKL 2732
Cdd:smart00787  222 IKVKKLEELEEELQELESKIE-----------DLTNKKSELNTEIAEAEKK-----LEQCRGFTFkEIEKLKEQL 280
PRK12704 PRK12704
phosphodiesterase; Provisional
 44-201 8.06e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 8.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    44 LEAALQKQKQKVENEKTEGTNLKRE-----NQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQEL 118
Cdd:PRK12704   33 IKEAEEEAKRILEEAKKEAEAIKKEalleaKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEEL 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   119 KRCKSELERSQQAAQSADVSLnpcntpQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEER---------KRLEAEVKALQ 189
Cdd:PRK12704  113 EKKEKELEQKQQELEKKEEEL------EELIEEQLQELERISGLTAEEAKEILLEKVEEEarheaavliKEIEEEAKEEA 186

                         170
                  ....*....|..
gi 55770834   190 AKKASQTLPQAT 201
Cdd:PRK12704  187 DKKAKEILAQAI 198
pepcterm_ChnLen TIGR03007
polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Members of this ...
 2215-2442 9.85e-03

polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Members of this protein family belong to the family of polysaccharide chain length determinant proteins (pfam02706). All are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria, and are found near the epsH homolog that is the putative exosortase gene. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274386 [Multi-domain]  Cd Length: 498  Bit Score: 41.58  E-value: 9.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2215 LTKQIQEKQGQLSELDKLLSSFKSlleEK----EQAEIQIKEESKTAVEMLQNQLKELNEAVAAL------CGDQEIMKA 2284
Cdd:TIGR03007  166 IDEQIKTYEKKLEAAENRLKAFKQ---ENggilPDQEGDYYSEISEAQEELEAARLELNEAIAQRdalkrqLGGEEPVLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2285 TEQSLDPPieeehQLRNSIEKLRARLEAdekkqlcvlQQLKESEHHADllkgrVENLERELEIARTNQEHAALEAENSKG 2364
Cdd:TIGR03007  243 AGSSVANS-----ELDGRIEALEKQLDA---------LRLRYTDKHPD-----VIATKREIAQLEEQKEEEGSAKNGGPE 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEK------VQMKEKSST 2438
Cdd:TIGR03007  304 RGEIANPVYQQLQIELAEAEAEIASLEARVAELTARIERLESLLRTIPEVEAELTQLNRDYEVNKsnyeqlLTRRESAEV 383


                   ....
gi 55770834   2439 AMEM 2442
Cdd:TIGR03007  384 SKQM 387
 
Name Accession Description Interval E-value
CENP-F_N pfam10481
Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound ...
 1-307 8.76e-136

Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound across the centromere as one of the proteins of the outer layer of the kinetochore. Most of the kinetochore/centromere functions appear to depend upon binding of the C-terminal par to f the molecule, whereas the N-terminal part, here, may be a cytoplasmic player in controlling the function of microtubules and dynein.


Pssm-ID: 463106 [Multi-domain]  Cd Length: 304  Bit Score: 427.32  E-value: 8.76e-136
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834      1 MSWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLE 80
Cdd:pfam10481    1 MSWAVEEWKEGLPTKALQKIQELESQLDKLKKERQQKQFQLESLEAALQKQKQKVENEKNEGSALKRENQSLMESCDNLE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     81 KTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYS 160
Cdd:pfam10481   81 KSRQKISHDLQVKESQVNFLEGQLNSSKKQIEKLEQELKRYKSELERSQQALLAGDVSLQPCSTPQKSFATPLTPSQRHN 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    161 GSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRD 240
Cdd:pfam10481  161 DSKYEELQEKYNKEVEERKRLEAELKVLQVKKTNQTLPQSTVSHRDIARHQASSSVFPWQQEKTPSRQSSDAQETPLKRG 240

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834    241 FSASYFSGEQEVTPSRSTLqigKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKE 307
Cdd:pfam10481  241 FTASHFLWEHEETPSKRSQ---RSSSNSSLQSNSSSSQLMDQLKAQNQELRSRVSELELRLQAQEKD 304
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2131-2270 1.87e-42

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 152.84  E-value: 1.87e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2131 DEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2211 EKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNE 2270
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2313-2452 4.62e-41

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 148.98  E-value: 4.62e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2313 DEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRS 2392
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2393 EKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNE 2452
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1983-2758 3.43e-28

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 125.17  E-value: 3.43e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1983 KMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLN 2062
Cdd:TIGR02168  233 RLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2063 KEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKL 2142
Cdd:TIGR02168  309 ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2143 KERERENDSLKDKVENLERELQMSEENQElvILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEK 2222
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRE--RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2223 QGQLSELDKLLSSFKSLLEEKEQaeiqikeeSKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 2302
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQA--------RLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2303 IEK-LRARLEA----DEKKQLCVLQQLKESEhhadllKGRVENLERELEIARTNQEHAALEAENSKG------EVETLKA 2371
Cdd:TIGR02168  539 IEAaLGGRLQAvvveNLNAAKKAIAFLKQNE------LGRVTFLPLDSIKGTEIQGNDREILKNIEGflgvakDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2372 KIEGMTQSLRGLELDVVTIRSekenlTNELQKE---QERISEL--EIINSSFeNILQEKEQEKVQMKEKSStAMEMLQTQ 2446
Cdd:TIGR02168  613 KLRKALSYLLGGVLVVDDLDN-----ALELAKKlrpGYRIVTLdgDLVRPGG-VITGGSAKTNSSILERRR-EIEELEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2447 LKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISR 2526
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2527 LKNQIqdqEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMS 2606
Cdd:TIGR02168  766 LEERL---EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2607 FVEKVNKMTAKETELQREMHEMAQKTAELQEEL---SGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDcmhk 2683
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELealLNERASLEEALALLRSELEELSEELRELESKRSELRRELE---- 918

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55770834   2684 dqvekegKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNN 2758
Cdd:TIGR02168  919 -------ELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP 986
CENP-F_C_Rb_bdg pfam10490
Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2967-3013 4.00e-20

Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. This domain is at the very C-terminus of the C-terminal coiled-coil, and is one of the key Rb-binding domains.


Pssm-ID: 463111  Cd Length: 47  Bit Score: 85.58  E-value: 4.00e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 55770834   2967 PAEDTEGTEFEPEGLPEVVKKGFADIPTGKTSPYILRRTTMATRTSP 3013
Cdd:pfam10490    1 NRAEQDDEEFEPEGLPEVVQKGFADIPSGEVSPYILRRTTLQLRCSP 47
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1977-2519 5.28e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.47  E-value: 5.28e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1977 LDQLSEKMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELEN 2056
Cdd:COG1196  241 LEELEAELEELEAELEELEAE----LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2057 QIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQL 2136
Cdd:COG1196  317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA 396

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2137 HIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLT 2216
Cdd:COG1196  397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2217 KQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEE 2296
Cdd:COG1196  477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2297 HQLRNSIEKLRARLEAdeKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGM 2376
Cdd:COG1196  557 EVAAAAIEYLKAAKAG--RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2377 TQSL-RGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVA 2455
Cdd:COG1196  635 ALRRaVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 55770834 2456 ALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEK 2519
Cdd:COG1196  715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2053-2603 6.10e-20

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 97.80  E-value: 6.10e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2053 ELENQIAQlnKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSS---TQEEVHQLRRGIEKLRVRIE 2129
Cdd:PRK02224  191 QLKAQIEE--KEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEheeRREELETLEAEIEDLRETIA 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2130 ADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Cdd:PRK02224  269 ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQN---QLKELNEAVAALCGDQEIMKATE 2286
Cdd:PRK02224  349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDapvDLGNAEDFLEELREERDELRERE 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2287 QSLDPPIEEehqLRNSIEKLRARLEADeKKQLCVlQQLKESEH--HADLLKGRVENLERELEIARTnqehaaleaenskg 2364
Cdd:PRK02224  429 AELEATLRT---ARERVEEAEALLEAG-KCPECG-QPVEGSPHveTIEEDRERVEELEAELEDLEE-------------- 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2365 EVETLKAKIEGMTqSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEmlq 2444
Cdd:PRK02224  490 EVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEE--- 565

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2445 tQLKELNERVAALHNDQEACKAKEQNLSSQVECLEL--EKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDE 2522
Cdd:PRK02224  566 -EAEEAREEVAELNSKLAELKERIESLERIRTLLAAiaDAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFD 644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2523 EiSRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQS---KNASLQDTLEVLQSSYKNLEnELEL 2599
Cdd:PRK02224  645 E-ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEElreRREALENRVEALEALYDEAE-ELES 722


                  ....
gi 55770834  2600 TKMD 2603
Cdd:PRK02224  723 MYGD 726
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2021-2862 7.60e-20

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 97.83  E-value: 7.60e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2021 SDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESEsLQARLSEsdYEKLNVSKALEAALVEK 2100
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQA-LLKEKRE--YEGYELLKEKEALERQK 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2101 GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKER-ERENDSLKDKVENLERELqmseenqelvildaEN 2179
Cdd:TIGR02169  240 EAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEI--------------AS 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2180 SKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGqlsELDKLLSSFKSLLEEKEQAEIQIKEESKTAVE 2259
Cdd:TIGR02169  306 LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERK---RRDKLTEEYAELKEELEDLRAELEEVDKEFAE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2260 MLQNQlkelneavaalcgdqeimKATEQSLDPPIEEehqlRNSIEKLRARLEaDEKKQlcvlqqlkesehhadlLKGRVE 2339
Cdd:TIGR02169  383 TRDEL------------------KDYREKLEKLKRE----INELKRELDRLQ-EELQR----------------LSEELA 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2340 NLERELEIARtnQEHAALEAenskgEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIinssfE 2419
Cdd:TIGR02169  424 DLNAAIAGIE--AKINELEE-----EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR-----E 491

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2420 NILQEKEQEKVQMKEKSSTAMEMLqtqlkeLNERVAALHndqeackakeqNLSSQVECLELEKAQLLQGLDEAKNNYIVL 2499
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEV------LKASIQGVH-----------GTVAQLGSVGERYATAIEVAAGNRLNNVVV 554

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2500 QSSvngliqevEDGKQKLE-KKDEEISRLK----NQIQDQEQLVSKLSQ----------VEGEHQ--------------- 2549
Cdd:TIGR02169  555 EDD--------AVAKEAIElLKRRKAGRATflplNKMRDERRDLSILSEdgvigfavdlVEFDPKyepafkyvfgdtlvv 626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2550 ----LWKEQNLELRNLTVELE------------QKIQVLQSKNASLQDTLEVLQSSYKNLENELEltkmdkmSFVEKVNK 2613
Cdd:TIGR02169  627 edieAARRLMGKYRMVTLEGElfeksgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELS-------SLQSELRR 699

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2614 MTAKETELQREMHEMAQKTAELQEELsgekNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKE---G 2690
Cdd:TIGR02169  700 IENRLDELSQELSDASRKIGEIEKEI----EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEedlH 775

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2691 KVREEIAEYQLRL-HEAEKKHQALLLDTNKqyevEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEE 2769
Cdd:TIGR02169  776 KLEEALNDLEARLsHSRIPEIQAELSKLEE----EVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS 851

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2770 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKtgtvmdTKVDELTTEIKELKET 2849
Cdd:TIGR02169  852 IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE------AQIEKKRKRLSELKAK 925

                          890
                   ....*....|...
gi 55770834   2850 LEEKTKEADEYLD 2862
Cdd:TIGR02169  926 LEALEEELSEIED 938
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1766-2491 6.21e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.12  E-value: 6.21e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1766 QEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1846 LEYFSCDHQELLQRVETS----EGLNSDL--EMHADKSSREDIGDNVAKVNDSWKERfldvENELSRIRS-EKASIEHEA 1918
Cdd:TIGR02168  360 LEELEAELEELESRLEELeeqlETLRSKVaqLELQIASLNNEIERLEARLERLEDRR----ERLQQEIEElLKKLEEAEL 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1919 LYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQ---ELESHQ 1995
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEgvkALLKNQ 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1996 SECLHCIQVA----EAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQI-AQLNKEKELLVK 2070
Cdd:TIGR02168  516 SGLSGILGVLseliSVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKgTEIQGNDREILK 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2071 ESESLQARLSESDYEKLNVSKALEAAL-----VEKGEFALRLSS---------TQEEVHQLRRGieklrVRIEADEKKQL 2136
Cdd:TIGR02168  596 NIEGFLGVAKDLVKFDPKLRKALSYLLggvlvVDDLDNALELAKklrpgyrivTLDGDLVRPGG-----VITGGSAKTNS 670

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2137 HIAEK---LKERERENDSLKDKVENLERELQMSEENQelvildaENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE 2213
Cdd:TIGR02168  671 SILERrreIEELEEKIEELEEKIAELEKALAELRKEL-------EELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2214 NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLdppi 2293
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA---- 819

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2294 eeeHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKI 2373
Cdd:TIGR02168  820 ---ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL 896

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2374 EGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEK----EQEKVQMKEKSSTAMEMLQTQLKE 2449
Cdd:TIGR02168  897 EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR 976

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 55770834   2450 LNERVAALHN-------DQEACKAKEQNLSSQVECLELEKAQLLQGLDE 2491
Cdd:TIGR02168  977 LENKIKELGPvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2033-2659 1.40e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.85  E-value: 1.40e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2033 LQEKLQslEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDyeklnvsKALEAALVEKGEFALRLSSTQE 2112
Cdd:COG1196  218 LKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE-------AELEELRLELEELELELEEAQA 288

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2113 EVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2192
Cdd:COG1196  289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2193 EMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2272
Cdd:COG1196  369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2273 AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLcVLQQLKESEHHADLLKGRVENLERELEIARTNQ 2352
Cdd:COG1196  449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL-LLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2353 EHAALEAenskgEVETlkakiegmtqslrglELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQM 2432
Cdd:COG1196  528 VLIGVEA-----AYEA---------------ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAA 587

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2433 KEKSSTAMEMLqtqlkelnERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVED 2512
Cdd:COG1196  588 LAAALARGAIG--------AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG 659

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2513 GKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKN 2592
Cdd:COG1196  660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE 739

                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834 2593 LENELELTKMDkmsFVEKVNKMTAKETELQREMHEMAQKTAEL----------QEELSGEKNRLAGELQLLLEEIKS 2659
Cdd:COG1196  740 ELLEEEELLEE---EALEELPEPPDLEELERELERLEREIEALgpvnllaieeYEELEERYDFLSEQREDLEEARET 813
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1900-2713 8.52e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 91.28  E-value: 8.52e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1900 VENELSRIRSEKA-SIEHEALYL---EADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKtt 1975
Cdd:TIGR02169  196 KRQQLERLRREREkAERYQALLKekrEYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQL-- 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1976 aLDQLSEKMKEKTQElESHQseclhcIQVAEAEVKEKTELLQTLSSDVSELLKDkthLQEKLQSLEKDSQALSLTKCELE 2055
Cdd:TIGR02169  274 -LEELNKKIKDLGEE-EQLR------VKEKIGELEAEIASLERSIAEKERELED---AEERLAKLEAEIDKLLAEIEELE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2056 NQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQ 2135
Cdd:TIGR02169  343 REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2136 LHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLvtlrSEKENL 2215
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQREL----AEAEAQ 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2216 TKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEM-----LQNQLKElNEAVAALCgdqeIMKATEQSLD 2290
Cdd:TIGR02169  499 ARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVaagnrLNNVVVE-DDAVAKEA----IELLKRRKAG 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2291 P----PIEEEHQLRNSIEKLRAR---------LEADEKKQLCVLQQLKESehhadLLKGRVENLERELEIARTnqehAAL 2357
Cdd:TIGR02169  574 RatflPLNKMRDERRDLSILSEDgvigfavdlVEFDPKYEPAFKYVFGDT-----LVVEDIEAARRLMGKYRM----VTL 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2358 EaenskGEVETLKAKIEGMTQSLRGLELDVvtiRSEKEnltnELQKEQERISELEIinsSFENILQEKEQEKVQMKEKSS 2437
Cdd:TIGR02169  645 E-----GELFEKSGAMTGGSRAPRGGILFS---RSEPA----ELQRLRERLEGLKR---ELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2438 tamemlqtQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEkaqlLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKL 2517
Cdd:TIGR02169  710 --------ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED----LSSLEQEIENVKSELKELEARIEELEEDLHKL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2518 EKKDEEISRLKNQiQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENEL 2597
Cdd:TIGR02169  778 EEALNDLEARLSH-SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEI 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2598 ELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRlageLQLLLEEIKSSKDQLKELTLENSELKKS 2677
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERK----IEELEAQIEKKRKRLSELKAKLEALEEE 932

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 55770834   2678 LdcmhkDQVEKEGKVREEIAEYQLRLHEAEKKHQAL 2713
Cdd:TIGR02169  933 L-----SEIEDPKGEDEEIPEEELSLEDVQAELQRV 963
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2120-2859 2.21e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 89.74  E-value: 2.21e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2120 GIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELvilDAENSKAEVETLKTQIEEMARSLK 2199
Cdd:TIGR02169  164 GVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAL---LKEKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2200 VFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAE-IQIKEEsktaVEMLQNQLKELNEAVAALCGD 2278
Cdd:TIGR02169  241 AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEqLRVKEK----IGELEAEIASLERSIAEKERE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2279 QEIMKATEQSLDppiEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARtnQEHAALe 2358
Cdd:TIGR02169  317 LEDAEERLAKLE---AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR--DELKDY- 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2359 aensKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEiinssfenilqEKEQEKVQMKEKSST 2438
Cdd:TIGR02169  391 ----REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELE-----------EEKEDKALEIKKQEW 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2439 AMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEV-------- 2510
Cdd:TIGR02169  456 KLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVaqlgsvge 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2511 ----------------------EDGKQKLE-KKDEEISRLK----NQIQDQEQLVSKLSQ----------VEGEHQ---- 2549
Cdd:TIGR02169  536 ryataievaagnrlnnvvveddAVAKEAIElLKRRKAGRATflplNKMRDERRDLSILSEdgvigfavdlVEFDPKyepa 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2550 ---------------LWKEQNLELRNLTVELE------------QKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKM 2602
Cdd:TIGR02169  616 fkyvfgdtlvvedieAARRLMGKYRMVTLEGElfeksgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQS 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2603 DKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLA-----------------GELQLLLEEIKSSKDQLK 2665
Cdd:TIGR02169  696 ELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEeleedlssleqeienvkSELKELEARIEELEEDLH 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2666 ELTLENSELKKSLDCMHKDQVEKE-GKVREEIAEYQLRLHEAEKKHQALLLDtnKQY-EVEIQTYREKLTSKEECLSSQK 2743
Cdd:TIGR02169  776 KLEEALNDLEARLSHSRIPEIQAElSKLEEEVSRIEARLREIEQKLNRLTLE--KEYlEKEIQELQEQRIDLKEQIKSIE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2744 LEIDLLKSSKEELNNSLKATTQILEELKKTKMDnlkyvnqLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQ 2823
Cdd:TIGR02169  854 KEIENLNGKKEELEEELEELEAALRDLESRLGD-------LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 55770834   2824 EKQKtgtvmdtkvDELTTEIKELKETLEEKTKEADE 2859
Cdd:TIGR02169  927 EALE---------EELSEIEDPKGEDEEIPEEELSL 953
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1950-2713 5.79e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 88.59  E-value: 5.79e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1950 EEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKE--------KTQELESHQSECLHCIQVAEAEVKEKTELLQTLSS 2021
Cdd:TIGR02169  186 IERLDLIIDEKRQQLERLRREREKAERYQALLKEKREyegyellkEKEALERQKEAIERQLASLEEELEKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2022 DVSELLKDKTHLQEKLQSLEKDSQALSLTKC-ELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEK 2100
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLGEEEQLRVKEKIgELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREI 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2101 GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENS 2180
Cdd:TIGR02169  346 EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADL 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2181 KAEVETLKTQI-------EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKE---QAEIQI 2250
Cdd:TIGR02169  426 NAAIAGIEAKIneleeekEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEaqaRASEER 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2251 KEESKTAVEMLQNQLKELNEAVAALCG-DQEIMKATEQSLDPP-----IEEEHQLRNSIEKLRAR--------------- 2309
Cdd:TIGR02169  506 VRGGRAVEEVLKASIQGVHGTVAQLGSvGERYATAIEVAAGNRlnnvvVEDDAVAKEAIELLKRRkagratflplnkmrd 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2310 --------------------LEADEKKQLCVLQQLK-----ESEHHADLLKGRVENLERELEI---------ARTNQEHA 2355
Cdd:TIGR02169  586 errdlsilsedgvigfavdlVEFDPKYEPAFKYVFGdtlvvEDIEAARRLMGKYRMVTLEGELfeksgamtgGSRAPRGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2356 ALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEiinSSFENILQEKEQEKVQMKEk 2435
Cdd:TIGR02169  666 ILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE---KEIEQLEQEEEKLKERLEE- 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2436 sstamemLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKnnyivlqssvnglIQEVEDGKQ 2515
Cdd:TIGR02169  742 -------LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR-------------IPEIQAELS 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2516 KLEkkdEEISRLKNQIQDQEQLVSKLSQ----VEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYK 2591
Cdd:TIGR02169  802 KLE---EEVSRIEARLREIEQKLNRLTLekeyLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2592 NLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLEN 2671
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQA 958

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 55770834   2672 SELKKSLDCMHKDQVEKegKVREEIAEYQLRLHEAEKKHQAL 2713
Cdd:TIGR02169  959 ELQRVEEEIRALEPVNM--LAIQEYEEVLKRLDELKEKRAKL 998
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2303-2852 1.71e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.37  E-value: 1.71e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2303 IEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRG 2382
Cdd:COG1196  234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2383 LELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEksstAMEMLQTQLKELNERVAALHNDQE 2462
Cdd:COG1196  314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE----ALLEAEAELAEAEEELEELAEELL 389

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2463 ACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLs 2542
Cdd:COG1196  390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL- 468

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2543 qvEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQ 2622
Cdd:COG1196  469 --LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAA 546

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2623 REMHEMAQKTAELQEELSGEKNRLAGELQLLLEEiKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLR 2702
Cdd:COG1196  547 ALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD-KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR 625

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2703 LHEAEKKHQALLLDTNKQYEVEIQTYREK---LTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLK 2779
Cdd:COG1196  626 TLVAARLEAALRRAVTLAGRLREVTLEGEggsAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE 705

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 55770834 2780 YVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEE 2852
Cdd:COG1196  706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1790-2677 1.78e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 80.50  E-value: 1.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1790 IEDRDRKVESLLNEMKELdsKLHLQEVQLMTKieaciELEKIVGELKKENsdlsEKLEYFScDHQELLQRVETSEGLNSD 1869
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEV--EENIERLDLIID-----EKRQQLERLRRER----EKAERYQ-ALLKEKREYEGYELLKEK 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1870 LEMHADKSSredigdnvakvndswkerfldVENELSRIRSEKASIEHE----ALYLEADLEVVQTEKLCLEKDNENKQkv 1945
Cdd:TIGR02169  233 EALERQKEA---------------------IERQLASLEEELEKLTEEiselEKRLEEIEQLLEELNKKIKDLGEEEQ-- 289

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1946 iVCLEEELSVVTSERNQLRGELDtmskkttALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSE 2025
Cdd:TIGR02169  290 -LRVKEKIGELEAEIASLERSIA-------EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2026 LLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFAL 2105
Cdd:TIGR02169  362 LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2106 RLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLkererenDSLKDKVENLERELQMSEENQELVILDAENSKAEVE 2185
Cdd:TIGR02169  442 EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY-------DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEE 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2186 TLKTQI--------------EEMARSLK----------VFELDLVTlrSEKENLTKQIQEKQGQLSELDKLLSSFKSLLE 2241
Cdd:TIGR02169  515 VLKASIqgvhgtvaqlgsvgERYATAIEvaagnrlnnvVVEDDAVA--KEAIELLKRRKAGRATFLPLNKMRDERRDLSI 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2242 EKEQAEIQIkeesktAVEMLQNQlKELNEAVAALCGDQEIMKATEQ-----------SLDPPIEEEH------------- 2297
Cdd:TIGR02169  593 LSEDGVIGF------AVDLVEFD-PKYEPAFKYVFGDTLVVEDIEAarrlmgkyrmvTLEGELFEKSgamtggsraprgg 665

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2298 -----QLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAK 2372
Cdd:TIGR02169  666 ilfsrSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED 745

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2373 IEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEiinssfenilQEKEQEKVQMKEKSstaMEMLQTQLKELNE 2452
Cdd:TIGR02169  746 LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLE----------ARLSHSRIPEIQAE---LSKLEEEVSRIEA 812

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2453 RVAALhndqeackakEQNLSSqvecLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIq 2532
Cdd:TIGR02169  813 RLREI----------EQKLNR----LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL- 877

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2533 dqEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENEL--ELTKMDKMSFVEK 2610
Cdd:TIGR02169  878 --RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKgeDEEIPEEELSLED 955

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834   2611 VNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEikssKDQLKELTLENSELKKS 2677
Cdd:TIGR02169  956 VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEE----RKAILERIEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1786-2491 1.85e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 80.11  E-value: 1.85e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1786 LLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEkleyfscdhQELLQRVETSEG 1865
Cdd:TIGR02169  228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE---------EEQLRVKEKIGE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1866 LNSDLE-----MHADKSSREDIGDNVAKVN---DSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEK 1937
Cdd:TIGR02169  299 LEAEIAslersIAEKERELEDAEERLAKLEaeiDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDK 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1938 DNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQ 2017
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2018 TLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQ----------------------------IAQLNKEKELLV 2069
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQaraseervrggraveevlkasiqgvhgtVAQLGSVGERYA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2070 KESES-----LQARLSESD----------------------YEKLNVSKALEAALVEKG-------------------EF 2103
Cdd:TIGR02169  539 TAIEVaagnrLNNVVVEDDavakeaiellkrrkagratflpLNKMRDERRDLSILSEDGvigfavdlvefdpkyepafKY 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2104 ALRLSSTQEEVHQLRRGIEKLR-VRIEAD--EKKQLHIAEKLKERERENDSLKDKvenlERELQMSEENQELvildaens 2180
Cdd:TIGR02169  619 VFGDTLVVEDIEAARRLMGKYRmVTLEGElfEKSGAMTGGSRAPRGGILFSRSEP----AELQRLRERLEGL-------- 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2181 KAEVETLKTQIEEMARSLKvfeldlvTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEqAEIQIKEESKTAVE- 2259
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLD-------ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE-EDLSSLEQEIENVKs 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2260 MLQNQLKELNEAVAALCGDQEIMKATEQSLDP-PIEEEHQLRNSIEKLRAR-------LEADEKKQLCVLQQLKESEHHA 2331
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEARLSHsRIPEIQAELSKLEEEVSRiearlreIEQKLNRLTLEKEYLEKEIQEL 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2332 ----DLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQER 2407
Cdd:TIGR02169  839 qeqrIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR 918

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2408 ISELEIINSSFENILQEKEQEKVQMKEKSSTAM--EMLQTQLKELNERVAALH-------NDQEACKAKEQNLSSQVECL 2478
Cdd:TIGR02169  919 LSELKAKLEALEEELSEIEDPKGEDEEIPEEELslEDVQAELQRVEEEIRALEpvnmlaiQEYEEVLKRLDELKEKRAKL 998

                          810
                   ....*....|...
gi 55770834   2479 ELEKAQLLQGLDE 2491
Cdd:TIGR02169  999 EEERKAILERIEE 1011
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 316-1160 6.74e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.56  E-value: 6.74e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    316 QELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQAsTKYTALEQKLKKLTEDLSCQRQNAESARcsleqkiKEKEKE 395
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKA-ERYKELKAELRELELALLVLRLEELREE-------LEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    396 FQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKEN 475
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    476 ELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLnqsqnfaEEMKAKNTSQETMLRDLQEKINQQENSLTLEK 555
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL-------EELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    556 LKLAVADLEKQRdcSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEyeelkeektlfscwksENEKLLTQMES 635
Cdd:TIGR02168  400 NEIERLEARLER--LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE----------------ELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    636 EKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLaymeLQQKAEFsDQKHQ 715
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV----LSELISV-DEGYE 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    716 KEIENMCLKTSQLTgQVEDLEHKLQ----LLSNEIMDKDRCYQDLHAEYE---SLRDLLKSKD------ASLVTNEDHQR 782
Cdd:TIGR02168  537 AAIEAALGGRLQAV-VVENLNAAKKaiafLKQNELGRVTFLPLDSIKGTEiqgNDREILKNIEgflgvaKDLVKFDPKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    783 SLLAF---------------DQQPAMHHSFANI------IGEQGSM--------------PSERSECRLEADQSPKNSAI 827
Cdd:TIGR02168  616 KALSYllggvlvvddldnalELAKKLRPGYRIVtldgdlVRPGGVItggsaktnssilerRREIEELEEKIEELEEKIAE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFvaetSQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL----EERIAQLSKELTELEAEIEELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    988 QEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEEtgnaYEDLSQKYKAAQEKNSKLECLLNECTSLCENR 1067
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE----LEELSEELRELESKRSELRRELEELREKLAQL 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1068 KNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDnQNNSKSEAGGLK----QEIMTLKEEQNKMQ 1143
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNlaaiEEYEELKERYDFLT 1006

                          890
                   ....*....|....*..
gi 55770834   1144 KEVNDLLQENEQLMKVM 1160
Cdd:TIGR02168 1007 AQKEDLTEAKETLEEAI 1023
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2053-2667 8.91e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 8.91e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2053 ELENQIAQLNKEKELLvKESESLQARLSESDyeklnvskaLEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADE 2132
Cdd:COG1196  197 ELERQLEPLERQAEKA-ERYRELKEELKELE---------AELLLLKLRELEAELEELEAELEELEAELEELEAELAELE 266

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2133 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEmarslkvfeldlvtLRSEK 2212
Cdd:COG1196  267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE--------------LEEEL 332

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2213 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPP 2292
Cdd:COG1196  333 EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2293 IEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAK 2372
Cdd:COG1196  413 LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2373 IEGMTQSLRGLE--LDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQmkEKSSTAMEMLQTQLKEL 2450
Cdd:COG1196  493 LLLLLEAEADYEgfLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVV--EDDEVAAAAIEYLKAAK 570

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2451 NERVAAL-HNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEisRLKN 2529
Cdd:COG1196  571 AGRATFLpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG--RLRE 648

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2530 QIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKmdkmsfvE 2609
Cdd:COG1196  649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE-------L 721

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 55770834 2610 KVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKEL 2667
Cdd:COG1196  722 EEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2063-2650 1.17e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 77.41  E-value: 1.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2063 KEKELLVKESESLQARLSESDYE---KLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIA 2139
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKEleeVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLE 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2140 EKLKERERENDSLKDKVENLERELQMSEENQELVIL---------DAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:PRK03918  259 EKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyiklsefyeEYLDELREIEKRLSRLEEEINGIEERIKELEEKEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2211 EKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLD 2290
Cdd:PRK03918  339 RLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2291 PPIEEehqLRNSIEKLR----------ARLEADEKKQLC---------VLQQLKESEHHADLLKGRVENLERELEIAR-- 2349
Cdd:PRK03918  419 KEIKE---LKKAIEELKkakgkcpvcgRELTEEHRKELLeeytaelkrIEKELKEIEEKERKLRKELRELEKVLKKESel 495

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2350 -----TNQEHAALEAENSKGEVETLKAKiegmTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQE 2424
Cdd:PRK03918  496 iklkeLAEQLKELEEKLKKYNLEELEKK----AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEE 571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2425 KEQEKVQMKEKSSTAMEMLQTQLKELNErvaaLHNDQEACKAKEQNLSSQVECLELEKaqllqgldeaknnyivlqssvn 2504
Cdd:PRK03918  572 LAELLKELEELGFESVEELEERLKELEP----FYNEYLELKDAEKELEREEKELKKLE---------------------- 625

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2505 gliQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSklsqvegehqlwKEQNLELRNLTVELEQKIQVLQSKNASLQDTLE 2584
Cdd:PRK03918  626 ---EELDKAFEELAETEKRLEELRKELEELEKKYS------------EEEYEELREEYLELSRELAGLRAELEELEKRRE 690

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 55770834  2585 VLQSSYKNLENELELTKMDKMSfVEKVNKMTAKETELQREMHEMaqkTAELQEELSGEKNRLAGEL 2650
Cdd:PRK03918  691 EIKKTLEKLKEELEEREKAKKE-LEKLEKALERVEELREKVKKY---KALLKERALSKVGEIASEI 752
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1772-2415 8.49e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 74.72  E-value: 8.49e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1772 LQLRVKETSNENL-RLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLmtkieacIELEKIVGELKKENSDLSEKLEYFS 1850
Cdd:PRK03918  155 LGLDDYENAYKNLgEVIKEIKRRIERLEKFIKRTENIEELIKEKEKEL-------EEVLREINEISSELPELREELEKLE 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1851 CDHQELLQRVETSEGLNSDLEmhadkssredigdNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEaDLEVVQT 1930
Cdd:PRK03918  228 KEVKELEELKEEIEELEKELE-------------SLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAE 293

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1931 EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELEshqseclhciqvaeaEVK 2010
Cdd:PRK03918  294 EYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLE---------------ELE 358

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2011 EKTELLQtlssDVSELLKDKTHLQEKLQSLEKDsqalsltkcELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVS 2090
Cdd:PRK03918  359 ERHELYE----EAKAKKEELERLKKRLTGLTPE---------KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELK 425

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2091 KALEAALVEKGEFAL--RLSSTQEEVHQLRRGIEKLRvRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEE 2168
Cdd:PRK03918  426 KAIEELKKAKGKCPVcgRELTEEHRKELLEEYTAELK-RIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQ 504

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2169 NQELvildaenskaEVETLKTQIEEMARSLKVFEL---DLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQ 2245
Cdd:PRK03918  505 LKEL----------EEKLKKYNLEELEKKAEEYEKlkeKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAE 574

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2246 AEIQIKEESKTAVEMLQNQLKElneavaalcgdqeimkateqsLDPPIEEEHQLRNSIEKLRARLEADEKKQlcvlQQLK 2325
Cdd:PRK03918  575 LLKELEELGFESVEELEERLKE---------------------LEPFYNEYLELKDAEKELEREEKELKKLE----EELD 629

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2326 ESEHHADLLKGRVENLERELEiaRTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQ 2405
Cdd:PRK03918  630 KAFEELAETEKRLEELRKELE--ELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707

                         650
                  ....*....|
gi 55770834  2406 ERISELEIIN 2415
Cdd:PRK03918  708 KAKKELEKLE 717
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2138-2814 1.04e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 74.29  E-value: 1.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2138 IAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTK 2217
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQK 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2218 QIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIkEESKTAVEMLQNQLKELNEAVAALcgdQEIMKATEQSLDppieeeh 2297
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLSNLKKKIQKNKSLESQI-SELKKQNNQLKDNIEKKQQEINEK---TTEISNTQTQLN------- 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2298 QLRNSIEKLRARLEadekkqlcvlqqlkesehhadllkgrvenlERELEIARTNQEHAALEAENSKGEVETLKAKIEGMT 2377
Cdd:TIGR04523  257 QLKDEQNKIKKQLS------------------------------EKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQ 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2378 QSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQmkeksstamemLQTQLKELNERVAAL 2457
Cdd:TIGR04523  307 DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSE-----------KQRELEEKQNEIEKL 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2458 HNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQL 2537
Cdd:TIGR04523  376 KKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELI 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2538 VSKLSQV-EGEHQLWKEQNLELRNLTVELEQKIQVLQSKNaslqDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTA 2616
Cdd:TIGR04523  456 IKNLDNTrESLETQLKVLSRSINKIKQNLEQKQKELKSKE----KELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2617 KETELQREMHEMAQKTAELQEELSgeKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEkegkVREEI 2696
Cdd:TIGR04523  532 EKKEKESKISDLEDELNKDDFELK--KENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKD----LIKEI 605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2697 AEYQLRLHEAEKKHQaLLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMD 2776
Cdd:TIGR04523  606 EEKEKKISSLEKELE-KAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKD 684

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 55770834   2777 NLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQK 2814
Cdd:TIGR04523  685 WLKELSLHYKKYITRMIRIKDLPKLEEKYKEIEKELKK 722
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2228-2796 1.12e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 74.33  E-value: 1.12e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2228 ELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQnQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLR 2307
Cdd:PRK03918  173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLR-EINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLE 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2308 ARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAAL--EAENSKGEVETLKAKIEGMTQSLRGLEL 2385
Cdd:PRK03918  252 GSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFyeEYLDELREIEKRLSRLEEEINGIEERIK 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2386 DVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACK 2465
Cdd:PRK03918  332 ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKIT 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2466 AKEQNLSSQVEclELEKAqlLQGLDEAKNnyivlQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVE 2545
Cdd:PRK03918  412 ARIGELKKEIK--ELKKA--IEELKKAKG-----KCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2546 GEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSF---VEKVNKMTAKETELQ 2622
Cdd:PRK03918  483 RELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLkkeLEKLEELKKKLAELE 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2623 REMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEgKVREEIAEYQLR 2702
Cdd:PRK03918  563 KKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELD-KAFEELAETEKR 641

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2703 LHEAEKKHQALLLDTNKQyevEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDnLKYVN 2782
Cdd:PRK03918  642 LEELRKELEELEKKYSEE---EYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKE-LEKLE 717

                         570
                  ....*....|....
gi 55770834  2783 QLKKENERAQGKMK 2796
Cdd:PRK03918  718 KALERVEELREKVK 731
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2446-2714 1.28e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 1.28e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2446 QLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEIS 2525
Cdd:COG1196  233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2526 RLKNQIQDQEQlvsKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKM 2605
Cdd:COG1196  313 ELEERLEELEE---ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2606 SFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDcMHKDQ 2685
Cdd:COG1196  390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE-LLAEL 468

                        250       260
                 ....*....|....*....|....*....
gi 55770834 2686 VEKEGKVREEIAEYQLRLHEAEKKHQALL 2714
Cdd:COG1196  469 LEEAALLEAALAELLEELAEAAARLLLLL 497
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2300-2882 2.49e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 69.71  E-value: 2.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2300 RNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEhaalEAENSKGEVETLKAKIEGMTQS 2379
Cdd:PRK03918  178 IERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK----ELEELKEEIEELEKELESLEGS 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2380 LRGLELDVVTIRSEKENLTNELQKEQERISELE---------IINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKEL 2450
Cdd:PRK03918  254 KRKLEEKIRELEERIEELKKEIEELEEKVKELKelkekaeeyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2451 NERVAALhndqEACKAKEQNLSSQVECLElEKAQLLQGLDEAKNNYIVLQSSVNGL--------IQEVEDGKQKLEKK-- 2520
Cdd:PRK03918  334 EEKEERL----EELKKKLKELEKRLEELE-ERHELYEEAKAKKEELERLKKRLTGLtpeklekeLEELEKAKEEIEEEis 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2521 --DEEISRLKNQIQDQEQLVSKLSQVEGE-----HQLWKEQNLEL-RNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKN 2592
Cdd:PRK03918  409 kiTARIGELKKEIKELKKAIEELKKAKGKcpvcgRELTEEHRKELlEEYTAELKRIEKELKEIEEKERKLRKELRELEKV 488

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2593 LENELELTKMDKMsfvekVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENS 2672
Cdd:PRK03918  489 LKKESELIKLKEL-----AEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEK 563

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2673 ELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLldtnkqyevEIQTYREKLTSKEECLSSQKLEIDLLKSS 2752
Cdd:PRK03918  564 KLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYL---------ELKDAEKELEREEKELKKLEEELDKAFEE 634

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2753 KEELNNSLKATTQILEELKKtkmdnlkyvNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKelsqlqaaqekqktgtvm 2832
Cdd:PRK03918  635 LAETEKRLEELRKELEELEK---------KYSEEEYEELREEYLELSRELAGLRAELEELEK------------------ 687

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|
gi 55770834  2833 dtKVDELTTEIKELKETLEEKTKEADEYldkycsllishEKLEKAKEMLE 2882
Cdd:PRK03918  688 --RREEIKKTLEKLKEELEEREKAKKEL-----------EKLEKALERVE 724
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2300-2679 3.33e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.71  E-value: 3.33e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2300 RNSIEKLRARLEADEKKQLcVLQQLKESEHHADLLKGRVENLERELEIARTNQEHA----ALEAENSKGEVETLKAKIEG 2375
Cdd:TIGR02169  156 RKIIDEIAGVAEFDRKKEK-ALEELEEVEENIERLDLIIDEKRQQLERLRREREKAeryqALLKEKREYEGYELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2376 MTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEiinssfenilQEKEQEKVQMKEKSSTAMEMLQTQLKELnerva 2455
Cdd:TIGR02169  235 LERQKEAIERQLASLEEELEKLTEEISELEKRLEEIE----------QLLEELNKKIKDLGEEEQLRVKEKIGEL----- 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2456 alHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEaknnyivLQSSVNGLIQEVEDGKQKLEKKDEEISRLKnqiQDQE 2535
Cdd:TIGR02169  300 --EAEIASLERSIAEKERELEDAEERLAKLEAEIDK-------LLAEIEELEREIEEERKRRDKLTEEYAELK---EELE 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2536 QLVSKLSQVEGEHQLWKEQnlelrnlTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMT 2615
Cdd:TIGR02169  368 DLRAELEEVDKEFAETRDE-------LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELE 440

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 55770834   2616 AKETELQREMHEMAQKTAELQEELSGEKNrlagELQLLLEEIKSSKDQLKELTLENSELKKSLD 2679
Cdd:TIGR02169  441 EEKEDKALEIKKQEWKLEQLAADLSKYEQ----ELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500
PTZ00121 PTZ00121
MAEBL; Provisional
 2069-2859 5.02e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.40  E-value: 5.02e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2069 VKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERE 2148
Cdd:PTZ00121 1066 VGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA 1145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2149 NDSLKDKVENLERELQMSEENQElvILDAENSKAEVETLKTqiEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSE 2228
Cdd:PTZ00121 1146 RKAEDAKRVEIARKAEDARKAEE--ARKAEDAKKAEAARKA--EEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAE 1221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2229 LDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQnqlKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSiEKLRa 2308
Cdd:PTZ00121 1222 DAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIR---KFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA-DEAK- 1296

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2309 rlEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDvv 2388
Cdd:PTZ00121 1297 --KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK-- 1372

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2389 tiRSEKENLTNELQKEQERISELEIINSSFENilQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKE 2468
Cdd:PTZ00121 1373 --KEEAKKKADAAKKKAEEKKKADEAKKKAEE--DKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADE 1448

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2469 QNLSSQveclELEKAQLLQGLDEAKnnyivlqssvngliQEVEDGKQKLEKKdEEISRLKNQIQDQEQLVSKLSQVEGEh 2548
Cdd:PTZ00121 1449 AKKKAE----EAKKAEEAKKKAEEA--------------KKADEAKKKAEEA-KKADEAKKKAEEAKKKADEAKKAAEA- 1508

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2549 qlwKEQNLELRnltvELEQKIQVLQSKNASLQDTLEVLQSSYKNLENElELTKMDKMSFVEKVNKmtAKETELQREMHEM 2628
Cdd:PTZ00121 1509 ---KKKADEAK----KAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD-ELKKAEELKKAEEKKK--AEEAKKAEEDKNM 1578

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2629 AQKTAELQEELsgEKNRLAGELQLLLEEIKSSKDQLKEltlenselkksldcmhkdqvEKEGKVREEiaeyQLRLHEAEK 2708
Cdd:PTZ00121 1579 ALRKAEEAKKA--EEARIEEVMKLYEEEKKMKAEEAKK--------------------AEEAKIKAE----ELKKAEEEK 1632

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2709 KHQALLldtnkqyeveiqtyreKLTSKEECLSSQKLEidllkssKEELNNSLKAttqilEELKKTKMDNLKYVNQLKKEN 2788
Cdd:PTZ00121 1633 KKVEQL----------------KKKEAEEKKKAEELK-------KAEEENKIKA-----AEEAKKAEEDKKKAEEAKKAE 1684

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 55770834  2789 ERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADE 2859
Cdd:PTZ00121 1685 EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE 1755
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1761-2271 6.21e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.55  E-value: 6.21e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1761 DFLGNQEDIHNLQLRVKETSNENLRLLHVIEDRDR-------KVESLLNEMKELDSKLHLQEVQL------MTKIEACI- 1826
Cdd:PRK03918  183 KFIKRTENIEELIKEKEKELEEVLREINEISSELPelreeleKLEKEVKELEELKEEIEELEKELeslegsKRKLEEKIr 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1827 ELEKIVGELKKENSDLSEKLEyfscDHQELLQRVETSEGLNSDLEMHADKSS---------REDIGDNVAKVND--SWKE 1895
Cdd:PRK03918  263 ELEERIEELKKEIEELEEKVK----ELKELKEKAEEYIKLSEFYEEYLDELReiekrlsrlEEEINGIEERIKEleEKEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1896 RFLDVENELSRIRSEKASIEHEA-LYLEADLEVVQTEKLCLEKDNENKQKvivcLEEELSVVTSERNQLRGELDTMSKKT 1974
Cdd:PRK03918  339 RLEELKKKLKELEKRLEELEERHeLYEEAKAKKEELERLKKRLTGLTPEK----LEKELEELEKAKEEIEEEISKITARI 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1975 TALDQLSEKMKEKTQELESHQSECLHCiqVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKdsqalsltkcEL 2054
Cdd:PRK03918  415 GELKKEIKELKKAIEELKKAKGKCPVC--GRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRK----------EL 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2055 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKaLEAALVEKGEFALRLSSTQEEVHQLRRGIEKLrvriEADEKK 2134
Cdd:PRK03918  483 RELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEE-LEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL----EELKKK 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2135 QLHIAEKLKERERENDSLKDKVENL--ERELQMSEENQEL-----VILDAENSKAEVETLKTQIEEMARSLKVFELDLVT 2207
Cdd:PRK03918  558 LAELEKKLDELEEELAELLKELEELgfESVEELEERLKELepfynEYLELKDAEKELEREEKELKKLEEELDKAFEELAE 637

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 55770834  2208 LRSEKENLTKQIQEKQGQLSELD---------KLLSSFKSLLEEKEQAEIQIKEESKTAvEMLQNQLKELNEA 2271
Cdd:PRK03918  638 TEKRLEELRKELEELEKKYSEEEyeelreeylELSRELAGLRAELEELEKRREEIKKTL-EKLKEELEEREKA 709
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2392-2887 7.79e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 68.12  E-value: 7.79e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2392 SEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSsTAMEMLQTQLKELNERVAALHNDQEACKAKEQNL 2471
Cdd:TIGR04523  152 KELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKL-LKLELLLSNLKKKIQKNKSLESQISELKKQNNQL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2472 SSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQ-------- 2543
Cdd:TIGR04523  231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNqkeqdwnk 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2544 -VEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNL-------ENELELTKMDKMSFVEKVNKMT 2615
Cdd:TIGR04523  311 eLKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKqreleekQNEIEKLKKENQSYKQEIKNLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2616 AKETELQREMHEMAQKTAELQEELSG---EKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKV 2692
Cdd:TIGR04523  391 SQINDLESKIQNQEKLNQQKDEQIKKlqqEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2693 REEIAEYQLRLHEAEKKHQALlldtnKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKK 2772
Cdd:TIGR04523  471 KVLSRSINKIKQNLEQKQKEL-----KSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2773 --TKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAaqekqktgtvmdtKVDELTTEIKELKETL 2850
Cdd:TIGR04523  546 elNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEK-------------EKKDLIKEIEEKEKKI 612

                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 55770834   2851 EEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAH 2887
Cdd:TIGR04523  613 SSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1921-2369 1.85e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 66.99  E-value: 1.85e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1921 LEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLH 2000
Cdd:PRK02224  256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRV 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2001 CIQVAEAEVKEKTELLQTLSSDVSELlkdkthlQEKLQSLEKDSQALSLTKCELENQIAQLNKE---------------- 2064
Cdd:PRK02224  336 AAQAHNEEAESLREDADDLEERAEEL-------REEAAELESELEEAREAVEDRREEIEELEEEieelrerfgdapvdlg 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2065 -----KELLVKESESLQARLSESDYEKLNVSKALEAAL--------------VEKGEFALRLSSTQEEVHQLRRGIEKLR 2125
Cdd:PRK02224  409 naedfLEELREERDELREREAELEATLRTARERVEEAEalleagkcpecgqpVEGSPHVETIEEDRERVEELEAELEDLE 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2126 VRIEADEKKqLHIAEKLKERERENDSLKDKVENL------------ERELQMSEENQELVILD--AENSKAEVETLKTQI 2191
Cdd:PRK02224  489 EEVEEVEER-LERAEDLVEAEDRIERLEERREDLeeliaerretieEKRERAEELRERAAELEaeAEEKREAAAEAEEEA 567

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2192 EEMARSLKVFELDLVTLRSEKENLTKqIQEKQGQLSELDKLLSSfkslLEEKEQAEIQIKEESKTAVEMLQNQLKELNEA 2271
Cdd:PRK02224  568 EEAREEVAELNSKLAELKERIESLER-IRTLLAAIADAEDEIER----LREKREALAELNDERRERLAEKRERKRELEAE 642

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2272 V--AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKqlcvLQQLKESEHHADLLKGRVENLERELEIAR 2349
Cdd:PRK02224  643 FdeARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENE----LEELEELRERREALENRVEALEALYDEAE 718

                         490       500
                  ....*....|....*....|.
gi 55770834  2350 TNQE-HAALEAENSKGEVETL 2369
Cdd:PRK02224  719 ELESmYGDLRAELRQRNVETL 739
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2129-2896 3.04e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.53  E-value: 3.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2129 EADEKKQLHIAEKLKERERENdslKDKVENLERElqmsEENQELVILDAENSKAEVETLKTQIEEMARSLKVfeLDLVTL 2208
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETEN---LAELIIDLEE----LKLQELKLKEQAKKALEYYQLKEKLELEEEYLLY--LDYLKL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2209 RSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVaalcgdQEIMKATEQS 2288
Cdd:pfam02463  235 NEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEEL------KSELLKLERR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2289 LDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAensKGEVET 2368
Cdd:pfam02463  309 KVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKK---KLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2369 LKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLK 2448
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2449 ELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLK 2528
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2529 NQIQDQEQLVSKLSQVEGEHqlwKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKmSFV 2608
Cdd:pfam02463  546 STAVIVEVSATADEVEERQK---LVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADED-DKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2609 EKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEK 2688
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2689 EGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILE 2768
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2769 ELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKE 2848
Cdd:pfam02463  782 KTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEE 861

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 55770834   2849 TLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQD 2896
Cdd:pfam02463  862 EITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKL 909
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 433-1187 3.64e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.23  E-value: 3.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    433 NVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNI 512
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    513 KQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVAdlEKQRDCSQDLLKKREHHIEQLNDKLSKTE 592
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL--EAELEELESRLEELEEQLETLRSKVAQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    593 KEsKALLSALElkkkeyeelkeektlfscwkSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEynERVRTLEMDR 672
Cdd:TIGR02168  393 LQ-IASLNNEI--------------------ERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQ--AELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    673 ENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKhQKEIENMCLKTSQLTGQVEDLEHKLQLLSNeimDKDRC 752
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR-LDSLERLQENLEGFSEGVKALLKNQSGLSG---ILGVL 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    753 YQDLH--AEYES--LRDLLKSKDASLVTNEDHQRSLLAFDQQPAMhhSFANIIGEQGSMPSERSECRLEADQSPKNSAIL 828
Cdd:TIGR02168  526 SELISvdEGYEAaiEAALGGRLQAVVVENLNAAKKAIAFLKQNEL--GRVTFLPLDSIKGTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    829 QNRVDslEFSLESQKQMNSDLQkqceeLVQIKGEIEE--NLMKAEQMHQSFVAETSQRISKLQEDTSAHqnvvAETLSAL 906
Cdd:TIGR02168  604 AKDLV--KFDPKLRKALSYLLG-----GVLVVDDLDNalELAKKLRPGYRIVTLDGDLVRPGGVITGGS----AKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    907 ENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASL 986
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    987 NQEKMNLIQKSESFANYIDEREKSISELS----------DQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECL 1056
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEaeieeleaqiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1057 LNECTSLCENRKNELEQLKEAFAK------EHQEFLTKLAFAEERNQNLMLELETVQQALRSE---MTDNQNNSKSEAGG 1127
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESlaaeieELEELIEELESELEALLNERASLEEALALLRSEleeLSEELRELESKRSE 912

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 55770834   1128 LKQEIMTLKEEQNKMQKEVNDLLQENEQL-----------MKVMKTKHECQNLESEPIRNSVKERESERNQ 1187
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLqerlseeysltLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2106-2737 4.40e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 65.71  E-value: 4.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2106 RLSSTQEEVHQLRRGIEKL-----------RVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVI 2174
Cdd:COG4913  236 DLERAHEALEDAREQIELLepirelaeryaAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2175 LDAENSKAEVETLKTQIeemaRSLKVFELDlvTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEES 2254
Cdd:COG4913  316 ARLDALREELDELEAQI----RGNGGDRLE--QLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2255 KTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSI----EKLRARLEA------DEKKQLCVLQQL 2324
Cdd:COG4913  390 AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIparlLALRDALAEalgldeAELPFVGELIEV 469

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2325 KESE-----------------------HHADL--------LKGRVeNLEReleiARTNQEHAALEAENSKGEVETLKAKI 2373
Cdd:COG4913  470 RPEEerwrgaiervlggfaltllvppeHYAAAlrwvnrlhLRGRL-VYER----VRTGLPDPERPRLDPDSLAGKLDFKP 544

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2374 EGMTQSLRGL---ELDVVTIRSEKE------NLTNELQ----------KEQERISELEIINSSFENILQEKEQEKVQMKE 2434
Cdd:COG4913  545 HPFRAWLEAElgrRFDYVCVDSPEElrrhprAITRAGQvkgngtrhekDDRRRIRSRYVLGFDNRAKLAALEAELAELEE 624

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2435 ksstAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKA-----QLLQGLDEAKNNYIVLQSSVNGLIQE 2509
Cdd:COG4913  625 ----ELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREiaeleAELERLDASSDDLAALEEQLEELEAE 700

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2510 VEDGKQKLEKKDEEISRLKNQIQD----QEQLVSKLSQVEGEHQLWKEQNLE-----------LRNLTVELEQKIQVLQS 2574
Cdd:COG4913  701 LEELEEELDELKGEIGRLEKELEQaeeeLDELQDRLEAAEDLARLELRALLEerfaaalgdavERELRENLEERIDALRA 780

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2575 KNASLQDTLEVLQSSYKnleNELELTKMDKMSFVEKVNKMTAKETELQRE-MHEMAQKTAELQEELSGEKnrLAGELQLL 2653
Cdd:COG4913  781 RLNRAEEELERAMRAFN---REWPAETADLDADLESLPEYLALLDRLEEDgLPEYEERFKELLNENSIEF--VADLLSKL 855

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2654 LEEIKSSKDQLKELtleNSELKksldcmHKD-------QVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQ 2726
Cdd:COG4913  856 RRAIREIKERIDPL---NDSLK------RIPfgpgrylRLEARPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALK 926

                        730
                 ....*....|.
gi 55770834 2727 TYREKLTSKEE 2737
Cdd:COG4913  927 RLIERLRSEEE 937
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 22-746 5.59e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 5.59e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     22 ELEGQLDKLKKEKQQRQ------FQLDSLEAALQKQKQKVENEKTEGTN--LKRENQRLMEICESLEKTKQKIS---HEL 90
Cdd:TIGR02168  197 ELERQLKSLERQAEKAErykelkAELRELELALLVLRLEELREELEELQeeLKEAEEELEELTAELQELEEKLEelrLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     91 QVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYysgsKYEDLKEK 170
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE----KLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    171 YNKEVEERKRLEAEVKALQAKKASQTlPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQ 250
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEELE-EQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    251 EVTPSRSTLQIGKRDANSSFFDNSssphlLDQLKAQNQELRNKINELELRLQGHEKEM---KGQVNKFQELQLQLE---K 324
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEE-----LERLEEALEELREELEEAEQALDAAERELaqlQARLDSLERLQENLEgfsE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    325 AKVELIEKEKVLNKCRD---ELVRTTAQYDQAstKYTALEQKLKKL-TEDLSCQRQNAES---------ARCSLEQKIKE 391
Cdd:TIGR02168  507 GVKALLKNQSGLSGILGvlsELISVDEGYEAA--IEAALGGRLQAVvVENLNAAKKAIAFlkqnelgrvTFLPLDSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    392 KEKEFQEELSRQQRSFQTLDQECIQMKARL-------------TQELQQAKNMHNVLQAEL------------------- 439
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvVDDLDNALELAKKLRPGYrivtldgdlvrpggvitgg 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    440 -DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQ 518
Cdd:TIGR02168  665 sAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    519 SQNFAEEMKAKNTSQETMLRDLQEKINqqENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKAL 598
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLE--EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    599 LSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVE 678
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    679 IRNLHNVLDSK------------SVEVETQKLAYMELQQKAEFSDQkHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI 746
Cdd:TIGR02168  903 LRELESKRSELrreleelreklaQLELRLEGLEVRIDNLQERLSEE-YSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2300-2883 9.80e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 64.68  E-value: 9.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2300 RNSIEKLRARLEADEKKQLcvLQQLKESEHHADLLKGRVENLERELEIARTNQEHAAL---EAENSKGEVETLKAKIEGM 2376
Cdd:PRK02224  186 RGSLDQLKAQIEEKEEKDL--HERLNGLESELAELDEEIERYEEQREQARETRDEADEvleEHEERREELETLEAEIEDL 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2377 TQSLRGLEldvvtirSEKENLTNELQKEQERISELEiinssfenilqEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAA 2456
Cdd:PRK02224  264 RETIAETE-------REREELAEEVRDLRERLEELE-----------EERDDLLAEAGLDDADAEAVEARREELEDRDEE 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2457 LHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEq 2536
Cdd:PRK02224  326 LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAP- 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2537 lvSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLE----------VLQSSYKNLENELEltkmdkms 2606
Cdd:PRK02224  405 --VDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpecgqpVEGSPHVETIEEDR-------- 474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2607 fvEKVNKMTAKETELQREMHEMAQKTAELQE--ELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKsldcmHKD 2684
Cdd:PRK02224  475 --ERVEELEAELEDLEEEVEEVEERLERAEDlvEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRE-----RAA 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2685 QVEKEGKVREEIAEyqlRLHEAEKKHQALLLDTNKQYEvEIQTYREKLTSKEECLSsqklEIDLLKSSKEELNNSLKATT 2764
Cdd:PRK02224  548 ELEAEAEEKREAAA---EAEEEAEEAREEVAELNSKLA-ELKERIESLERIRTLLA----AIADAEDEIERLREKREALA 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2765 QILEELKKtkmdnlkyvnQLKKENERAqgkmkllikscKQLEEEKEilqkeLSQLQAAQEKQKTGTVMDTKVDELTTEIK 2844
Cdd:PRK02224  620 ELNDERRE----------RLAEKRERK-----------RELEAEFD-----EARIEEAREDKERAEEYLEQVEEKLDELR 673

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 55770834  2845 ELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLET 2883
Cdd:PRK02224  674 EERDDLQAEIGAVENELEELEELRERREALENRVEALEA 712
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 288-568 1.10e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  288 QELRNKINELELRLQGH-----EKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ 362
Cdd:COG1196  216 RELKEELKELEAELLLLklrelEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  363 KLKKLTEDLSCQRQNAESARcsleqKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKL 442
Cdd:COG1196  296 ELARLEQDIARLEERRRELE-----ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  443 TSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNF 522
Cdd:COG1196  371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 55770834  523 AEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRD 568
Cdd:COG1196  451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 283-1020 1.15e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 1.15e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    283 LKAQNQELRNKINELE---LRLQGHEKEMKGQVNKfqeLQLQLEKAKvELIEKEKVLNKCRDELvrTTAQYDQASTKYTA 359
Cdd:TIGR02168  170 YKERRKETERKLERTRenlDRLEDILNELERQLKS---LERQAEKAE-RYKELKAELRELELAL--LVLRLEELREELEE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    360 LEQKLKKLTEDLscqrqNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL 439
Cdd:TIGR02168  244 LQEELKEAEEEL-----EELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQS 519
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    520 QNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALL 599
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    600 SALELKKKEYEELKEEKTLFscwksENEKLLTQMESEKENLQSKINHLETCLKtQQIKSHEYNER--VRTLEMDRENLSV 677
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQ-----ENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAaiEAALGGRLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    678 EIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLH 757
Cdd:TIGR02168  553 ENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    758 AEYESLRDLlkSKDASLVTNEDH----------------------QRSLLAFDQQPAMHHSFANII--------GEQGSM 807
Cdd:TIGR02168  633 NALELAKKL--RPGYRIVTLDGDlvrpggvitggsaktnssilerRREIEELEEKIEELEEKIAELekalaelrKELEEL 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    808 PSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMhqsfVAETSQRISK 887
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE----LAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    888 LQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKR 967
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 55770834    968 EIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQ 1020
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 2069-2827 1.30e-09

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 64.22  E-value: 1.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2069 VKESESLQARLSESDYEKLNVSkaleaALVEKGEFALRLSSTQEEVHQLRRGIEKLrvrieadekkqlHIAEKLKERERE 2148
Cdd:TIGR00618  125 KSETEEVIHDLLKLDYKTFTRV-----VLLPQGEFAQFLKAKSKEKKELLMNLFPL------------DQYTQLALMEFA 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2149 ND-SLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLS 2227
Cdd:TIGR00618  188 KKkSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRA 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2228 ELDKLLSSFKSLLEEKEQAEIQIKEEsktavemlqnQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLR 2307
Cdd:TIGR00618  268 RIEELRAQEAVLEETQERINRARKAA----------PLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQ 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2308 ARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELE----IARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGL 2383
Cdd:TIGR00618  338 SSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTltqhIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTS 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2384 ELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKsstAMEMLQTQLKELNERVAALHNDQEA 2463
Cdd:TIGR00618  418 AFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLK---EREQQLQTKEQIHLQETRKKAVVLA 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2464 CKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNG---LIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSK 2540
Cdd:TIGR00618  495 RLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTyaqLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSI 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2541 LSQVEGEhqlWKEQNLELRNLTVELEQKIQVL----QSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTA 2616
Cdd:TIGR00618  575 LTQCDNR---SKEDIPNLQNITVRLQDLTEKLseaeDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHAL 651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2617 KETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEI 2696
Cdd:TIGR00618  652 QLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLG 731

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2697 AEYQLR---LHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKT 2773
Cdd:TIGR00618  732 SDLAARedaLNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE 811

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 55770834   2774 KMDNL--KYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKE--LSQLQAAQEKQK 2827
Cdd:TIGR00618  812 IPSDEdiLNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEecSKQLAQLTQEQA 869
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1791-2536 3.61e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 62.83  E-value: 3.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1791 EDRDRKVESLLNEMKELDSKLH----LQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVEtsegl 1866
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNesneLHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQ----- 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1867 NSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEkasiehealyleadleVVQTEKLCLEKDNENKQKVI 1946
Cdd:pfam15921  149 NTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSI----------------LVDFEEASGKKIYEHDSMST 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1947 VCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQE-----LESHQSECLHCIQVAEAEVKEKTELLQTLSS 2021
Cdd:pfam15921  213 MHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARS 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2022 DVSELLKDKTHLQEklQSLEKDSQALSLTKcELENQIAQLNKEkelLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2101
Cdd:pfam15921  293 QANSIQSQLEIIQE--QARNQNSMYMRQLS-DLESTVSQLRSE---LREAKRMYEDKIEELEKQLVLANSELTEARTERD 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2102 EFALRLSSTQEEVHQLRRGIEKLR--VRIEADEKKQL------------HIAEKLKERERENDSLKDKVENLERELQMSE 2167
Cdd:pfam15921  367 QFSQESGNLDDQLQKLLADLHKREkeLSLEKEQNKRLwdrdtgnsitidHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2168 ENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKEN-------LTKQIQEKQGQLSELDKLLSSFKSLL 2240
Cdd:pfam15921  447 ERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESsertvsdLTASLQEKERAIEATNAEITKLRSRV 526

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2241 EEKEQAEIQIKEES------KTAVEMLQNQLKELNEAVaalcgdqEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADE 2314
Cdd:pfam15921  527 DLKLQELQHLKNEGdhlrnvQTECEALKLQMAEKDKVI-------EILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEI 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2315 KKQLCVLQQLKESEHHADL----LKGRVENLERE---LEIARTNQEHAALEAENSK----GEVETLKAKIEGMTQSLRGL 2383
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAkireLEARVSDLELEkvkLVNAGSERLRAVKDIKQERdqllNEVKTSRNELNSLSEDYEVL 679

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2384 ELDVVTIRSEKENLTNELQKE-QERISELEIINSSFENIL-QEKEQEKVQM-KEKSSTA----MEMLQTQLKELNERVAA 2456
Cdd:pfam15921  680 KRNFRNKSEEMETTTNKLKMQlKSAQSELEQTRNTLKSMEgSDGHAMKVAMgMQKQITAkrgqIDALQSKIQFLEEAMTN 759

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2457 LHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDeaknnyiVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQ 2536
Cdd:pfam15921  760 ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELE-------VLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQ 832
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 280-598 4.70e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 4.70e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    280 LDQLKAQNQELRNKINELELRLQGHEKEmKGQVNKFQELQLQLEKAKVELIEKEKvlNKCRDELVRTTAQYDqastkytA 359
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEK--EALERQKEAIERQLA-------S 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLT---QELQQAKNMHNVLQ 436
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAekeRELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCL 516
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    517 NQSQNFAEEMKAKNTSQETMLRDLQEKINQQENslTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESK 596
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEE--EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELS 486


                   ..
gi 55770834    597 AL 598
Cdd:TIGR02169  487 KL 488
PTZ00121 PTZ00121
MAEBL; Provisional
 2170-2963 6.94e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 6.94e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2170 QELVILDAEN---SKAEVETLKTQIEEMARSLKVFELDlvtlrSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQA 2246
Cdd:PTZ00121 1045 KDIIDEDIDGnheGKAEAKAHVGQDEGLKPSYKDFDFD-----AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEE 1119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2247 EIQIKEESKTAVEMLQ-NQLKELNEAVAAlcGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLcvlQQLK 2325
Cdd:PTZ00121 1120 AKKKAEDARKAEEARKaEDARKAEEARKA--EDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKA---EELR 1194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2326 ESEHHADLLKGRVENLERELEIARTNQEHAALEA-----ENSKGEVETLKAKIEGMTQSLRGLELDVVT--------IRS 2392
Cdd:PTZ00121 1195 KAEDARKAEAARKAEEERKAEEARKAEDAKKAEAvkkaeEAKKDAEEAKKAEEERNNEEIRKFEEARMAhfarrqaaIKA 1274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2393 EKENLTNELQKEQERISELEIINSSFENILQE--KEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQN 2470
Cdd:PTZ00121 1275 EEARKADELKKAEEKKKADEAKKAEEKKKADEakKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEA 1354

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2471 LSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGlIQEVEDGKQKLE---KKDEEISRLKNQIQDQEQLVSKLSQVEGE 2547
Cdd:PTZ00121 1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEE-KKKADEAKKKAEedkKKADELKKAAAAKKKADEAKKKAEEKKKA 1433

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2548 HQLWKEqnlelrnltVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHE 2627
Cdd:PTZ00121 1434 DEAKKK---------AEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKK 1504

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2628 MAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE 2707
Cdd:PTZ00121 1505 AAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2708 ---KKHQALLLDTNKQYEVEIQTYREKLTSKEEclssQKLEIDLLKSSKEElnnslkatTQILEELKKTKMDNLKYVNQL 2784
Cdd:PTZ00121 1585 eakKAEEARIEEVMKLYEEEKKMKAEEAKKAEE----AKIKAEELKKAEEE--------KKKVEQLKKKEAEEKKKAEEL 1652

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2785 KKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKY 2864
Cdd:PTZ00121 1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKA 1732

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2865 CSLLISHEKLEKAKEML------ETQVAHLCSQQSKQDSRGSPLLGPVVpgPSPIPSVTEKRLSSGQNKASGKRQRSSGI 2938
Cdd:PTZ00121 1733 EEAKKEAEEDKKKAEEAkkdeeeKKKIAHLKKEEEKKAEEIRKEKEAVI--EEELDEEDEKRRMEVDKKIKDIFDNFANI 1810

                         810       820
                  ....*....|....*....|....*...
gi 55770834  2939 WENGRGPTP---ATPESFSKKSKKAVMS 2963
Cdd:PTZ00121 1811 IEGGKEGNLvinDSKEMEDSAIKEVADS 1838
PTZ00121 PTZ00121
MAEBL; Provisional
 1971-2540 1.30e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 1.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1971 SKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKdsQALSLT 2050
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK--KAEEKK 1391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2051 KCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAAlvEKGEFALRLSSTQEEVHQLRRGIEKLRvriEA 2130
Cdd:PTZ00121 1392 KADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAK--KKAEEAKKADEAKKKAEEAKKAEEAKK---KA 1466

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2131 DEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQElvildaENSKAEvETLKTQIEEMARSLKVFEldlvtlRS 2210
Cdd:PTZ00121 1467 EEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAE------AKKKAD-EAKKAEEAKKADEAKKAE------EA 1533

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2211 EKENLTKQIQEKQgQLSELDKLLSSFKSllEEKEQAEIQIKEESKTAV-----EMLQNQLKELNEAVAALCGDQEIMKAT 2285
Cdd:PTZ00121 1534 KKADEAKKAEEKK-KADELKKAEELKKA--EEKKKAEEAKKAEEDKNMalrkaEEAKKAEEARIEEVMKLYEEEKKMKAE 1610

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2286 EqsldppIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGE 2365
Cdd:PTZ00121 1611 E------AKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2366 VETLKAKiegmtQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQT 2445
Cdd:PTZ00121 1685 EDEKKAA-----EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKI 1759

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2446 QLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQgldEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEIS 2525
Cdd:PTZ00121 1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK---DIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVA 1836

                         570
                  ....*....|....*
gi 55770834  2526 RLKNQIQDQEQLVSK 2540
Cdd:PTZ00121 1837 DSKNMQLEEADAFEK 1851
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2590-2888 1.60e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 1.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2590 YKNLENELE-----LTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSgeknrlagELQLLLEEIKSSKDQL 2664
Cdd:TIGR02168  215 YKELKAELRelelaLLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE--------ELRLEVSELEEEIEEL 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2665 KELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQyeveiqtyREKLTSKEECLSSQKL 2744
Cdd:TIGR02168  287 QKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL--------EEKLEELKEELESLEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2745 EIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELsQLQAAQE 2824
Cdd:TIGR02168  359 ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL-EEAELKE 437

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 55770834   2825 KQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHL 2888
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2395-2882 2.01e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.46  E-value: 2.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2395 ENLTNELQKEQERISELEIINSSFENI---LQEKEQEKVQMKEKSSTAMEMLQTQLKELnERVAALHNDQEACKAKEQNL 2471
Cdd:PRK03918  165 KNLGEVIKEIKRRIERLEKFIKRTENIeelIKEKEKELEEVLREINEISSELPELREEL-EKLEKEVKELEELKEEIEEL 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2472 SSQVECLELEKAQLLQGLDEaknnyivLQSSVNGLIQEVEDgkqkLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLW 2551
Cdd:PRK03918  244 EKELESLEGSKRKLEEKIRE-------LEERIEELKKEIEE----LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREI 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2552 KEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLqssyKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQK 2631
Cdd:PRK03918  313 EKRLSRLEEEINGIEERIKELEEKEERLEELKKKL----KELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEK 388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2632 TAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKS----------LDCMHKDQVEKEgkVREEIAEYQL 2701
Cdd:PRK03918  389 LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpvcgreLTEEHRKELLEE--YTAELKRIEK 466

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2702 RLHEAEKKHQALlldtnKQYEVEIqtyrEKLTSKEECLSSQKLEIDLLKSSKEELNN----SLKATTQILEELKKTKMDN 2777
Cdd:PRK03918  467 ELKEIEEKERKL-----RKELREL----EKVLKKESELIKLKELAEQLKELEEKLKKynleELEKKAEEYEKLKEKLIKL 537

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2778 LKYVNQLKKENERAQG---KMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMD-----TKVDELTTEIKELKET 2849
Cdd:PRK03918  538 KGEIKSLKKELEKLEElkkKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKElepfyNEYLELKDAEKELERE 617

                         490       500       510
                  ....*....|....*....|....*....|...
gi 55770834  2850 LEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 2882
Cdd:PRK03918  618 EKELKKLEEELDKAFEELAETEKRLEELRKELE 650
PRK11281 PRK11281
mechanosensitive channel MscK;
2140-2584 2.54e-08

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 59.93  E-value: 2.54e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2140 EKLKERERENDSLKDKVENLERELQmsEENQELVILDAENSKAEVETLKTqieemarslkvfeLDLVTLRSEKENLTKQI 2219
Cdd:PRK11281   73 DKIDRQKEETEQLKQQLAQAPAKLR--QAQAELEALKDDNDEETRETLST-------------LSLRQLESRLAQTLDQL 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2220 QEKQGQLSELDKLLSSFKSLLeEKEQAEIQikeESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLdppieeehqL 2299
Cdd:PRK11281  138 QNAQNDLAEYNSQLVSLQTQP-ERAQAALY---ANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQAL---------L 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2300 RNSIEKLRARLEADEkkqlcVLQQLKESEHhaDLLKGRVENLERELEIART--NQEHAALeAENSKGEVETLKAKIEGMT 2377
Cdd:PRK11281  205 NAQNDLQRKSLEGNT-----QLQDLLQKQR--DYLTARIQRLEHQLQLLQEaiNSKRLTL-SEKTVQEAQSQDEAARIQA 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2378 QSLRGLELDVVTirsekeNLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSStameMLQTQL---KELNERV 2454
Cdd:PRK11281  277 NPLVAQELEINL------QLSQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQIS----VLKGSLllsRILYQQQ 346

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2455 AALHNDQEackakEQNLSSQVECLELEKAQLLQGLDEAknnyivlqSSVNGLIQEVEDGkQKLEKKDEEISRLKNQIQDQ 2534
Cdd:PRK11281  347 QALPSADL-----IEGLADRIADLRLEQFEINQQRDAL--------FQPDAYIDKLEAG-HKSEVTDEVRDALLQLLDER 412

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 55770834  2535 EQLVSKLSqvegehqlwKEQNLELrNLTVELEQKIQVLQSKNASLQDTLE 2584
Cdd:PRK11281  413 RELLDQLN---------KQLNNQL-NLAINLQLNQQQLLSVSDSLQSTLT 452
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 4-720 2.74e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 2.74e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834      4 ALEEWKEGLptrALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTK 83
Cdd:TIGR02168  221 ELRELELAL---LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     84 QKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTtpltpsqyysgSK 163
Cdd:TIGR02168  298 SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE-----------AE 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    164 YEDLKEKYNKEVEERKRLEAEVKALQAKKASQtlpqatMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSA 243
Cdd:TIGR02168  367 LEELESRLEELEEQLETLRSKVAQLELQIASL------NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    244 SYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQElQLQLE 323
Cdd:TIGR02168  441 ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN-QSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    324 KAK---VELIEKEKVLNKCRDELVRTTAQY-----------------DQASTKYTALEQKLKKLTEDLSCQRQNAESARC 383
Cdd:TIGR02168  520 GILgvlSELISVDEGYEAAIEAALGGRLQAvvvenlnaakkaiaflkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEG 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    384 SLEQKIKEKEKEFQ------------------------EELSRQQRSFQTLDQECIQMKARLTQE--------LQQAKNM 431
Cdd:TIGR02168  600 FLGVAKDLVKFDPKlrkalsyllggvlvvddldnalelAKKLRPGYRIVTLDGDLVRPGGVITGGsaktnssiLERRREI 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    432 HNvLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKN 511
Cdd:TIGR02168  680 EE-LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    512 IKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEK------------LKLAVADLEKQRDCSQDLLKKREH 579
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRealdelraeltlLNEEAANLRERLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    580 HIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSH 659
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE 918

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 55770834    660 EYNERVRTLEMDRENLSVEIRNLhnvLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIEN 720
Cdd:TIGR02168  919 ELREKLAQLELRLEGLEVRIDNL---QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 280-514 3.23e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 3.23e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Cdd:COG1196  262 LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE 341

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQEciqmkARLTQELQQAKNMHNVLQAEL 439
Cdd:COG1196  342 LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA-----AELAAQLEELEEAEEALLERL 416

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55770834  440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQ 514
Cdd:COG1196  417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1949-2402 3.61e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 59.75  E-value: 3.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKM------KEKTQELESHQSECLHCIQVAEA--------------- 2007
Cdd:pfam15921  347 LEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLladlhkREKELSLEKEQNKRLWDRDTGNSitidhlrrelddrnm 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2008 EVKEKTELLQTLSSDVS-ELLKDKTHLQEKLQSLEKDSqalSLTkcelenqiAQLNKEKELLVKESESLQARL-----SE 2081
Cdd:pfam15921  427 EVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEKVS---SLT--------AQLESTKEMLRKVVEELTAKKmtlesSE 495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2082 SDYEKLNVS-----KALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERErendSLKDKV 2156
Cdd:pfam15921  496 RTVSDLTASlqekeRAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIE----ILRQQI 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2157 ENLER----------ELQMSEENQELVILDAENSKAEVETLK----TQIEEMARSLKVFELD---LVTLRSEKENLTKQI 2219
Cdd:pfam15921  572 ENMTQlvgqhgrtagAMQVEKAQLEKEINDRRLELQEFKILKdkkdAKIRELEARVSDLELEkvkLVNAGSERLRAVKDI 651

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2220 QEKQGQL-SELDKLLSSFKSLLEEKEQAEIQIKEESKtAVEMLQNQLK-ELNEAVAALCGDQEIMKATEQSLDPPIEEEH 2297
Cdd:pfam15921  652 KQERDQLlNEVKTSRNELNSLSEDYEVLKRNFRNKSE-EMETTTNKLKmQLKSAQSELEQTRNTLKSMEGSDGHAMKVAM 730

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2298 QLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGM- 2376
Cdd:pfam15921  731 GMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMe 810

                          490       500       510
                   ....*....|....*....|....*....|
gi 55770834   2377 ----TQSLRGLELDVVTIRSEKENLTNELQ 2402
Cdd:pfam15921  811 valdKASLQFAECQDIIQRQEQESVRLKLQ 840
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2213-2647 4.14e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 59.01  E-value: 4.14e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2213 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEesktavemLQNQLKELNEAVAALcgdqeimkateqsldPP 2292
Cdd:COG4717   74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEE--------LREELEKLEKLLQLL---------------PL 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2293 IEEEHQLRNSIEKLRARLEADEKKqlcvLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEA-ENSKGEVETLKA 2371
Cdd:COG4717  131 YQELEALEAELAELPERLEELEER----LEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQ 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2372 KIEGMTQSLRGLELDVVTIRSEKENLTNEL--QKEQERISELEIINSSFeNILQEKEQEKVQMKEKSSTAMEMLQTQLKE 2449
Cdd:COG4717  207 RLAELEEELEEAQEELEELEEELEQLENELeaAALEERLKEARLLLLIA-AALLALLGLGGSLLSLILTIAGVLFLVLGL 285

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2450 LNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLK- 2528
Cdd:COG4717  286 LALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQl 365

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2529 NQIQDQEQLVSKLSQVEGEHQLWK--EQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQssYKNLENELELTKMDKMS 2606
Cdd:COG4717  366 EELEQEIAALLAEAGVEDEEELRAalEQAEEYQELKEELEELEEQLEELLGELEELLEALD--EEELEEELEELEEELEE 443

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|...
gi 55770834 2607 FVEKVNKMTAKETELQREMHEMAQKT--AELQEELSGEKNRLA 2647
Cdd:COG4717  444 LEEELEELREELAELEAELEQLEEDGelAELLQELEELKAELR 486
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1853-2360 4.29e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 4.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1853 HQELL---QRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWK--ERFLDVENELSRIRSEKASIEHEALYLEADLEV 1927
Cdd:COG4913  241 HEALEdarEQIELLEPIRELAERYAAARERLAELEYLRAALRLWFaqRRLELLEAELEELRAELARLEAELERLEARLDA 320

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1928 VQTEKLCLEKD-NENKQKVIVCLEEELSVVTSERNQLRGELDTMSKkttALDQLSEKMKEKTQELESHQSECLHCIQVAE 2006
Cdd:COG4913  321 LREELDELEAQiRGNGGDRLEQLEREIERLERELEERERRRARLEA---LLAALGLPLPASAEEFAALRAEAAALLEALE 397

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2007 AEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEkdSQALSLTKcELENQIAQLnkEKELLVKES------ESLQARLS 2080
Cdd:COG4913  398 EELEALEEALAEAEAALRDLRRELRELEAEIASLE--RRKSNIPA-RLLALRDAL--AEALGLDEAelpfvgELIEVRPE 472

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2081 ESDYEKlnvskALEAALvekGEFALRLSSTQE---------EVHQLRRGI--EKLRVRIEADEKKQLH---IAEKLKERE 2146
Cdd:COG4913  473 EERWRG-----AIERVL---GGFALTLLVPPEhyaaalrwvNRLHLRGRLvyERVRTGLPDPERPRLDpdsLAGKLDFKP 544

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2147 RE-----NDSLKD-----KVENLE----------RELQMS------------EENQELVIldAENSKAEVETLKTQIEEM 2194
Cdd:COG4913  545 HPfrawlEAELGRrfdyvCVDSPEelrrhpraitRAGQVKgngtrhekddrrRIRSRYVL--GFDNRAKLAALEAELAEL 622

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2195 ARSLKVFELDLVTLRSEKENLTKQIQEKQgQLSELDKLLSSFKSLLEEKEQAEIQIK--EESKTAVEMLQNQLKELNEAV 2272
Cdd:COG4913  623 EEELAEAEERLEALEAELDALQERREALQ-RLAEYSWDEIDVASAEREIAELEAELErlDASSDDLAALEEQLEELEAEL 701

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2273 AALCGDQEIMKATEQSLDppiEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL--EIART 2350
Cdd:COG4913  702 EELEEELDELKGEIGRLE---KELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLeeRIDAL 778

                        570
                 ....*....|
gi 55770834 2351 NQEHAALEAE 2360
Cdd:COG4913  779 RARLNRAEEE 788
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 360-588 5.49e-08

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 58.71  E-value: 5.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    360 LEQKLKKLTEDLSCQRQNAESAR--CSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQaknMHNVLQA 437
Cdd:pfam09726  400 LEQDIKKLKAELQASRQTEQELRsqISSLTSLERSLKSELGQLRQENDLLQTKLHNAVSAKQKDKQTVQQ---LEKRLKA 476

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    438 ELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENE----LRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIK 513
Cdd:pfam09726  477 EQEARASAEKQLAEEKKRKKEEEATAARAVALAAASRGEctesLKQRKRELESEIKKLTHDIKLKEEQIRELEIKVQELR 556

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    514 QCLNQSQNFAEEMKAkntsqetmLRDLQEKINQQENSLTLE-KLKL----AVADLEKQRDCSQDLLKKREHHIEQLNDKL 588
Cdd:pfam09726  557 KYKESEKDTEVLMSA--------LSAMQDKNQHLENSLSAEtRIKLdlfsALGDAKRQLEIAQGQIYQKDQEIKDLKQKI 628
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 435-708 5.99e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 5.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    435 LQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQ 514
Cdd:TIGR02169  672 EPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    515 clnqsqnfaeemkaKNTSQETMLRDLQEKINQQEnsLTLEKLKLAVADLEKqrdcsqdllKKREHHIEQLNDKLSKTEKE 594
Cdd:TIGR02169  752 --------------EIENVKSELKELEARIEELE--EDLHKLEEALNDLEA---------RLSHSRIPEIQAELSKLEEE 806

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    595 SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEK-------ENLQSKINHLETCLKTQQIKSHEYNERVRT 667
Cdd:TIGR02169  807 VSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIksiekeiENLNGKKEELEEELEELEAALRDLESRLGD 886

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 55770834    668 LEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAE 708
Cdd:TIGR02169  887 LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 623-1251 6.11e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 6.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    623 KSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHN---VLDSKSVEVETQKLA 699
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQqkqILRERLANLERQLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    700 YMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNED 779
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    780 HQRSLLAFDQQpamhhsfaniigeqgsmpSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQI 859
Cdd:TIGR02168  401 EIERLEARLER------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    860 KGEIEENLMKAEQMHQSFVAETSQRISKL-----------------------QEDTSAHQNVVAETLSALENKEKEL--- 913
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQARLdslerlqenlegfsegvkallknQSGLSGILGVLSELISVDEGYEAAIeaa 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    914 ------QLLNDKVETEQAEIQELKKSNH-----LLEDSLKELQLLSETLSLEKKEMSSIISLNKRE-------------- 968
Cdd:TIGR02168  543 lggrlqAVVVENLNAAKKAIAFLKQNELgrvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVkfdpklrkalsyll 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    969 -----IEELTQENGTLKEINA-----SLNQEKMN----LIQKSESFANYIDEREKSISELSdqykQEKLILLQRCEETGN 1034
Cdd:TIGR02168  623 ggvlvVDDLDNALELAKKLRPgyrivTLDGDLVRpggvITGGSAKTNSSILERRREIEELE----EKIEELEEKIAELEK 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1035 AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAK-------------EHQEFLTKLAFAEERNQNLML 1101
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQleeriaqlskeltELEAEIEELEERLEEAEEELA 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1102 ELETVQQALRSEMTDNQNN---SKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSV 1178
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEElkaLREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 55770834   1179 KERESERNQCNfKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQ 1251
Cdd:TIGR02168  859 AEIEELEELIE-ELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR 930
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2564-2893 1.11e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.16  E-value: 1.11e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2564 ELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELEL-TKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELqEELSGE 2642
Cdd:TIGR02169  181 EVEENIERLDLIIDEKRQQLERLRREREKAERYQALlKEKREYEGYELLKEKEALERQKEAIERQLASLEEEL-EKLTEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2643 KNRLAGELQLLLEEIKSSKDQLKELTLENS-ELKKSldcMHKDQVEKEgKVREEIAEYQLRLHEAEKKHQallldtnkQY 2721
Cdd:TIGR02169  260 ISELEKRLEEIEQLLEELNKKIKDLGEEEQlRVKEK---IGELEAEIA-SLERSIAEKERELEDAEERLA--------KL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2722 EVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKS 2801
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2802 CKQLEEEKEILQKELSQLQAAQEKQKTG-TVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEM 2880
Cdd:TIGR02169  408 LDRLQEELQRLSEELADLNAAIAGIEAKiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSK 487

                          330
                   ....*....|...
gi 55770834   2881 LETQVAHLCSQQS 2893
Cdd:TIGR02169  488 LQRELAEAEAQAR 500
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1796-2570 1.24e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.72  E-value: 1.24e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1796 KVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLeyfSCDHQELLQRVETSEGLNSDLEMHAD 1875
Cdd:TIGR04523   41 KLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKL---KKNKDKINKLNSDLSKINSEIKNDKE 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1876 -KSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELs 1954
Cdd:TIGR04523  118 qKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKL- 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1955 vvtSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSsdvSELLKDKTHLQ 2034
Cdd:TIGR04523  197 ---LKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLK---DEQNKIKKQLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2035 EKLQSLEKDSQALSltkcELENQIAQLNKEKELLVKESESlqarlsesdyeklnvskaleaalvekgefalrlsstqeev 2114
Cdd:TIGR04523  271 EKQKELEQNNKKIK----ELEKQLNQLKSEISDLNNQKEQ---------------------------------------- 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2115 hqlrRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEM 2194
Cdd:TIGR04523  307 ----DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSY 382

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2195 ARSLKVFELDLVTLRSEKENLTKQIQEKQGQLseldkllssfKSLLEEKEQAEIQIKEESKTaVEMLQNQLKELNEAVAA 2274
Cdd:TIGR04523  383 KQEIKNLESQINDLESKIQNQEKLNQQKDEQI----------KKLQQEKELLEKEIERLKET-IIKNNSEIKDLTNQDSV 451

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2275 LCGDQEIMKATEQSLDPPIEEehqLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEH 2354
Cdd:TIGR04523  452 KELIIKNLDNTRESLETQLKV---LSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK 528

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2355 AALEAENSKGEVETLKAKIEGMTQslrglELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKE 2434
Cdd:TIGR04523  529 LESEKKEKESKISDLEDELNKDDF-----ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIK 603

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2435 KsstaMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGK 2514
Cdd:TIGR04523  604 E----IEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDII 679

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 55770834   2515 QKLEKKDEEIS-----RLKNQI--QDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQ 2570
Cdd:TIGR04523  680 ELMKDWLKELSlhykkYITRMIriKDLPKLEEKYKEIEKELKKLDEFSKELENIIKNFNKKFD 742
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2623-2930 1.44e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 1.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2623 REMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLdcmhKDQVEKEGKVREEIAEYQLR 2702
Cdd:COG1196  235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEER 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2703 LHEAEKKHQALlldtnkqyEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVN 2782
Cdd:COG1196  311 RRELEERLEEL--------EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2783 QLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQktgtvmDTKVDELTTEIKELKETLEEKTKEADEYLD 2862
Cdd:COG1196  383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL------EEALAELEEEEEEEEEALEEAAEEEAELEE 456

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 55770834 2863 KYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPLLGPVVPGPSPIPSVTEKRLSSGQNKASG 2930
Cdd:COG1196  457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 280-988 1.56e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 1.56e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRttaqydqASTKYTA 359
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER-------LEARLER 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL 439
Cdd:TIGR02168  412 LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQ-----ASQIK-ENELRRSMEEMKKE--NNLLKSHSEQKAREVCHLE----- 506
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGilgvlSELISvDEGYEAAIEAALGGrlQAVVVENLNAAKKAIAFLKqnelg 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    507 ----AELKNIKQCLNQSQNfaEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADlekQRDCSQDLLKKREHHI- 581
Cdd:TIGR02168  572 rvtfLPLDSIKGTEIQGND--REILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD---DLDNALELAKKLRPGYr 646

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    582 ------EQLNDKLSKTEKESKALLSALelkkkeyeelkeektlfscwksENEKLLTQMESEKENLQSKINHLETCLKTQQ 655
Cdd:TIGR02168  647 ivtldgDLVRPGGVITGGSAKTNSSIL----------------------ERRREIEELEEKIEELEEKIAELEKALAELR 704

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    656 IKSHEYNERVRTLEMDRENLSVEIRNLHNVLdsKSVEVETQKLAYMELQQKAEFSDQKHQKE-----IENMCLKTSQLTG 730
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDL--ARLEAEVEQLEERIAQLSKELTELEAEIEeleerLEEAEEELAEAEA 782

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    731 QVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEdhQRSLLAFDQQPAMHHSFANIIGEQGSMPSE 810
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE--RRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    811 RSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFV---AETSQRISK 887
Cdd:TIGR02168  861 IEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLElrlEGLEVRIDN 940

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    888 LQEDTSAHQNVVAETLSALENK-EKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNK 966
Cdd:TIGR02168  941 LQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLE 1020

                          730       740
                   ....*....|....*....|....*..
gi 55770834    967 REIEELTQE-----NGTLKEINASLNQ 988
Cdd:TIGR02168 1021 EAIEEIDREarerfKDTFDQVNENFQR 1047
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2130-2709 1.77e-07

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 57.22  E-value: 1.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2130 ADEKKQLHIAEKLKERERENDSLKDKVENLERELQmseeNQELVILDAENSKAEVETLKTQIEEMARSLKVFEldlvtlr 2209
Cdd:PRK01156  149 AQRKKILDEILEINSLERNYDKLKDVIDMLRAEIS----NIDYLEEKLKSSNLELENIKKQIADDEKSHSITL------- 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK--EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEq 2287
Cdd:PRK01156  218 KEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKtaESDLSMELEKNNYYKELEERHMKIINDPVYKNRNY- 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2288 sldppIEEEHQLRNSIEKLRARLE---ADEKKQLCVLQQLkesehhADLLKGRVENLERELEIARTNQEHAALEAENSK- 2363
Cdd:PRK01156  297 -----INDYFKYKNDIENKKQILSnidAEINKYHAIIKKL------SVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDy 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2364 ----GEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERI-SELEIINSSFENiLQEKEQEKVQMKEKSST 2438
Cdd:PRK01156  366 nsylKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEInVKLQDISSKVSS-LNQRIRALRENLDELSR 444

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2439 AMEMLQ---------TQLKELNERVAALHNDQEACKakeqnLSSQVECLELEkaqlLQGLDEAKNNYIVLQSSVNG-LIQ 2508
Cdd:PRK01156  445 NMEMLNgqsvcpvcgTTLGEEKSNHIINHYNEKKSR-----LEEKIREIEIE----VKDIDEKIVDLKKRKEYLESeEIN 515

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2509 EVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRN------LTVELEQKIQVLQSKNASLQDT 2582
Cdd:PRK01156  516 KSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRtswlnaLAVISLIDIETNRSRSNEIKKQ 595

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2583 LEVLQSSYKNLENELEltkmDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQllleEIKSSKD 2662
Cdd:PRK01156  596 LNDLESRLQEIEIGFP----DDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIA----EIDSIIP 667

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834  2663 QLKELTLENSE-------LKKSLDCMHKDQVEKEGKV---REEIAEYQLRLHEAEKK 2709
Cdd:PRK01156  668 DLKEITSRINDiednlkkSRKALDDAKANRARLESTIeilRTRINELSDRINDINET 724
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2034-2275 2.01e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 2.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2034 QEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQaRLSESDYEKLNVsKALEAALVEKGEFALRLSSTQEE 2113
Cdd:COG4913  609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQ-RLAEYSWDEIDV-ASAEREIAELEAELERLDASSDD 686

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2114 VHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQ-MSEENQELVILDAENSKAEvETLKTQIE 2192
Cdd:COG4913  687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEaAEDLARLELRALLEERFAA-ALGDAVER 765

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2193 EMARSLkvfELDLVTLRSEKENLTKQIQEKQGQ----------------------LSELDKLLSS--------FKSLLEE 2242
Cdd:COG4913  766 ELRENL---EERIDALRARLNRAEEELERAMRAfnrewpaetadldadleslpeyLALLDRLEEDglpeyeerFKELLNE 842

                        250       260       270
                 ....*....|....*....|....*....|....
gi 55770834 2243 KEQAEI-QIKEESKTAVEMLQNQLKELNEAVAAL 2275
Cdd:COG4913  843 NSIEFVaDLLSKLRRAIREIKERIDPLNDSLKRI 876
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2104-2363 2.44e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 2.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2104 ALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAE 2183
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2184 VETLKTQIEEMARSLkvfeldlvtlrsekenltkqiqEKQGQLSELDKLLSSfKSLLEEKEQAEI--QIKEESKTAVEML 2261
Cdd:COG4942   99 LEAQKEELAELLRAL----------------------YRLGRQPPLALLLSP-EDFLDAVRRLQYlkYLAPARREQAEEL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2262 QNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESehhADLLKGRVENL 2341
Cdd:COG4942  156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE---AEELEALIARL 232

                        250       260
                 ....*....|....*....|..
gi 55770834 2342 ERELEIARTNQEHAALEAENSK 2363
Cdd:COG4942  233 EAEAAAAAERTPAAGFAALKGK 254
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 2107-2598 2.88e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 56.65  E-value: 2.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2107 LSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVET 2186
Cdd:pfam05483  284 LKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEE 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2187 L----KTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEiQIKEESKTAVEMLQ 2262
Cdd:pfam05483  364 LlrteQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFE-KIAEELKGKEQELI 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2263 NQLKELNEAVAALCGDQEIMKATEQSLDPPIEEehqLRNSIEKlrarleadekkqlcvlQQLKESEHHADLLKGRVENLE 2342
Cdd:pfam05483  443 FLLQAREKEIHDLEIQLTAIKTSEEHYLKEVED---LKTELEK----------------EKLKNIELTAHCDKLLLENKE 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2343 RELEIArtnqeHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNEL-QKEQERISELEIINSSFENI 2421
Cdd:pfam05483  504 LTQEAS-----DMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFiQKGDEVKCKLDKSEENARSI 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2422 LQEKEQEKVQMKEKSSTAMEmLQTQLKELNERVAALHNDQEACKAKEQNLSSQ-------VECLELEKAQLLQGLDEAKN 2494
Cdd:pfam05483  579 EYEVLKKEKQMKILENKCNN-LKKQIENKNKNIEELHQENKALKKKGSAENKQlnayeikVNKLELELASAKQKFEEIID 657

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2495 NYI----VLQSSVNGLIQEVEDGK----QKLEKKDEEISRLKNQIQDQEQLVSK--------LSQVEGEHQLWKEQNLEL 2558
Cdd:pfam05483  658 NYQkeieDKKISEEKLLEEVEKAKaiadEAVKLQKEIDKRCQHKIAEMVALMEKhkhqydkiIEERDSELGLYKNKEQEQ 737

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 55770834   2559 RNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELE 2598
Cdd:pfam05483  738 SSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAK 777
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1919-2721 3.16e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.52  E-value: 3.16e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1919 LYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSEC 1998
Cdd:pfam02463  232 LKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1999 LHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQAR 2078
Cdd:pfam02463  312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2079 LSESDYEKLNVSKAleAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVEN 2158
Cdd:pfam02463  392 LKEEELELKSEEEK--EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKK 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2159 LERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKS 2238
Cdd:pfam02463  470 SEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2239 LLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQL 2318
Cdd:pfam02463  550 IVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGIL 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2319 CVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLT 2398
Cdd:pfam02463  630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2399 NELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECL 2478
Cdd:pfam02463  710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVE 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2479 ELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSqvegehqlwKEQNLEL 2558
Cdd:pfam02463  790 EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAE---------EELERLE 860

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2559 RNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEE 2638
Cdd:pfam02463  861 EEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL 940

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2639 LSGEKNRLAGELQLLLEEIKSSKDQLKELtlensELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTN 2718
Cdd:pfam02463  941 LLEEADEKEKEENNKEEEEERNKRLLLAK-----EELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEET 1015


                   ...
gi 55770834   2719 KQY 2721
Cdd:pfam02463 1016 CQR 1018
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1980-2302 3.19e-07

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 56.09  E-value: 3.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1980 LSEKMKEKTQELesHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQalSLTKCELENQIA 2059
Cdd:PRK05771   14 LKSYKDEVLEAL--HELGVVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKK--KVSVKSLEELIK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2060 QLNKEKELLVKESESLQARLSESDYEKlnvsKALEAALVEkgefALRLSSTQEEVHQLRRG----IEKLRVRIEADEKKQ 2135
Cdd:PRK05771   90 DVEEELEKIEKEIKELEEEISELENEI----KELEQEIER----LEPWGNFDLDLSLLLGFkyvsVFVGTVPEDKLEELK 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2136 LhIAEKLKEREREND---------SLKDKVENLERELQmSEENQELVILDAENSKAEVETLKTQIEEmarslkvfeldlv 2206
Cdd:PRK05771  162 L-ESDVENVEYISTDkgyvyvvvvVLKELSDEVEEELK-KLGFERLELEEEGTPSELIREIKEELEE------------- 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2207 tLRSEKENLTKQIQEKQGQLSELdkLLSSFKSLLEEKEQAEIQIKE-ESKTAVeMLQ-----NQLKELNEAVAALCGDQE 2280
Cdd:PRK05771  227 -IEKERESLLEELKELAKKYLEE--LLALYEYLEIELERAEALSKFlKTDKTF-AIEgwvpeDRVKKLKELIDKATGGSA 302

                         330       340
                  ....*....|....*....|....*
gi 55770834  2281 IMkateQSLDPPIEEEH---QLRNS 2302
Cdd:PRK05771  303 YV----EFVEPDEEEEEvptKLKNP 323
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1895-2460 3.39e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.46  E-value: 3.39e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1895 ERFLDVENELSRIRSEKASIEHEALYLEADLEvvqteKLCLEKDNENKQKvivcLEEELSVVTSERNQLRGELDTMSKK- 1973
Cdd:COG4913  262 ERYAAARERLAELEYLRAALRLWFAQRRLELL-----EAELEELRAELAR----LEAELERLEARLDALREELDELEAQi 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1974 ----TTALDQLSEKMKEKTQELESHQSEclhciqvaEAEVKEKTELLQ-TLSSDVSELLKDKTHLQEKLQSLEKDSQALS 2048
Cdd:COG4913  333 rgngGDRLEQLEREIERLERELEERERR--------RARLEALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALE 404

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2049 LTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGE---FALRLSSTQEEVHQLRRGIEKL- 2124
Cdd:COG4913  405 EALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAelpFVGELIEVRPEEERWRGAIERVl 484

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2125 ---RVRI---EADEKKQLHIAEKLKERERENdslKDKVENLERELQMS--EENQELVILDAENSKAEvETLKTQIEEMAR 2196
Cdd:COG4913  485 ggfALTLlvpPEHYAAALRWVNRLHLRGRLV---YERVRTGLPDPERPrlDPDSLAGKLDFKPHPFR-AWLEAELGRRFD 560

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2197 SLKVfeLDLVTLRSEKENLTKQIQEKQ-GQLSELDKllssfksllEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAAL 2275
Cdd:COG4913  561 YVCV--DSPEELRRHPRAITRAGQVKGnGTRHEKDD---------RRRIRSRYVLGFDNRAKLAALEAELAELEEELAEA 629

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2276 cgdqeimkateqsldppIEEEHQLRNSIEKLRARLEADEKkqlcvLQQLKESEHHADLLKGRVENLERELE-IARTNQEH 2354
Cdd:COG4913  630 -----------------EERLEALEAELDALQERREALQR-----LAEYSWDEIDVASAEREIAELEAELErLDASSDDL 687

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2355 AALEAenskgEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKE 2434
Cdd:COG4913  688 AALEE-----QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA 762

                        570       580
                 ....*....|....*....|....*.
gi 55770834 2435 KSSTAMEMLQTQLKELNERVAALHND 2460
Cdd:COG4913  763 VERELRENLEERIDALRARLNRAEEE 788
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1956-2852 3.50e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 56.59  E-value: 3.50e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1956 VTSERNQLRGELDTMSKKTTALDQLSEKMKE--------------------KTQELESHQSEC-LHCIQVAEAEVKEKTE 2014
Cdd:TIGR00606  226 ITSKEAQLESSREIVKSYENELDPLKNRLKEiehnlskimkldneikalksRKKQMEKDNSELeLKMEKVFQGTDEQLND 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2015 LLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNkekellvKESESLQARLSESDYEKLNVSKALE 2094
Cdd:TIGR00606  306 LYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQ-------LQADRHQEHIRARDSLIQSLATRLE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2095 AALVEKGEFALRlssTQEEVHQLRRGIEKLRVRIEADEKKQLhiAEKLKERERENDSLKDKVENLERELQMSEENQELVI 2174
Cdd:TIGR00606  379 LDGFERGPFSER---QIKNFHTLVIERQEDEAKTAAQLCADL--QSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2175 LDAENSKAEVETLKT---QIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKsllEEKEQAEIQIK 2251
Cdd:TIGR00606  454 EELKFVIKELQQLEGssdRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRK---LDQEMEQLNHH 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2252 EESKTAVEMLqnqlkelneAVAALCGDQEIMKATEQSLDPPIEEEHQLRNsieklrarleadeKKQLCvlQQLKESEHHA 2331
Cdd:TIGR00606  531 TTTRTQMEML---------TKDKMDKDEQIRKIKSRHSDELTSLLGYFPN-------------KKQLE--DWLHSKSKEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2332 DLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSlRGLELDVvtirsekENLTNELQKEQERISEL 2411
Cdd:TIGR00606  587 NQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEESDL-------ERLKEEIEKSSKQRAML 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2412 EIINSSFENILQEKEQEKvqmKEKSSTAMEMLQTQlKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLqGLDE 2491
Cdd:TIGR00606  659 AGATAVYSQFITQLTDEN---QSCCPVCQRVFQTE-AELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEML-GLAP 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2492 AKNNYIVLQssvnglIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQ-------LWKEQNLELRNLTVE 2564
Cdd:TIGR00606  734 GRQSIIDLK------EKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcltdvtIMERFQMELKDVERK 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2565 LEQKIQVLQSKNASLQDT-----LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQeEL 2639
Cdd:TIGR00606  808 IAQQAAKLQGSDLDRTVQqvnqeKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQ-QF 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2640 SGEKNRLAGELQLLLEEIKSSKDQ-------LKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQA 2712
Cdd:TIGR00606  887 EEQLVELSTEVQSLIREIKDAKEQdspletfLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQD 966

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2713 LLLDTNKQYEVEIQTYREKLTSKE-------ECLSSQKLEIDLLKSSKEEL--NNSLKATTQILEELKKTKMDNLKYVN- 2782
Cdd:TIGR00606  967 GKDDYLKQKETELNTVNAQLEECEkhqekinEDMRLMRQDIDTQKIQERWLqdNLTLRKRENELKEVEEELKQHLKEMGq 1046

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2783 ----QLKKENERAQGKMKLL-------IKSCKQLEEEKEILQKELS--QLQAAQEKQKTGTVMDTKVDELTTEIKELKET 2849
Cdd:TIGR00606 1047 mqvlQMKQEHQKLEENIDLIkrnhvlaLGRQKGYEKEIKHFKKELRepQFRDAEEKYREMMIVMRTTELVNKDLDIYYKT 1126


                   ...
gi 55770834   2850 LEE 2852
Cdd:TIGR00606 1127 LDQ 1129
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2208-2743 3.95e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.28  E-value: 3.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2208 LRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQ 2287
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2288 SLDPPIEEEHQLRNSiEKLRARLEADEKKQLC---------VLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALE 2358
Cdd:pfam15921  342 DKIEELEKQLVLANS-ELTEARTERDQFSQESgnlddqlqkLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2359 AENSKGEVETLKAKIEGMTQSLRG-LELDVVTIRSEKENLtnelQKEQERISELEIINSSFENILQEKEQEKVQMkEKSS 2437
Cdd:pfam15921  421 LDDRNMEVQRLEALLKAMKSECQGqMERQMAAIQGKNESL----EKVSSLTAQLESTKEMLRKVVEELTAKKMTL-ESSE 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2438 TAMEMLQTQLKELNERVaalhndqEACKAKEQNLSSQVECleleKAQLLQGLDEAKNNYIVLQSSVNGLiqevedgKQKL 2517
Cdd:pfam15921  496 RTVSDLTASLQEKERAI-------EATNAEITKLRSRVDL----KLQELQHLKNEGDHLRNVQTECEAL-------KLQM 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2518 EKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQ--------NLELRNLTVELEQKIQVLQSKNASLQDtLEVLQSS 2589
Cdd:pfam15921  558 AEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQlekeindrRLELQEFKILKDKKDAKIRELEARVSD-LELEKVK 636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2590 YKNLENE----LELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLK 2665
Cdd:pfam15921  637 LVNAGSErlraVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLK 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2666 ELTLENSELKKSLDCMHKDQVEKEGKV---REEIAEYQLRLHEAEKKHQALLLDTNK--QYEVEIQTYREKLTSKEECLS 2740
Cdd:pfam15921  717 SMEGSDGHAMKVAMGMQKQITAKRGQIdalQSKIQFLEEAMTNANKEKHFLKEEKNKlsQELSTVATEKNKMAGELEVLR 796


                   ...
gi 55770834   2741 SQK 2743
Cdd:pfam15921  797 SQE 799
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1795-2692 4.50e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 56.21  E-value: 4.50e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1795 RKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGlnsdLEMHA 1874
Cdd:TIGR00606  241 KSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQ----RTVRE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1875 DKSSREDIGDNVAKVNDSWKE---RFLDVENELSR-----------IRSEKASIEHEALYLEAD---------LEVVQTE 1931
Cdd:TIGR00606  317 KERELVDCQRELEKLNKERRLlnqEKTELLVEQGRlqlqadrhqehIRARDSLIQSLATRLELDgfergpfseRQIKNFH 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1932 KLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSEclhcIQVAEAEVKE 2011
Cdd:TIGR00606  397 TLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKE----LQQLEGSSDR 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2012 KTELLQTLSSDVSELLK-DKTHLQEKLQ----SLEKDSQALSLTKCELENQIAQLNKEK------ELLVKESESLQARLS 2080
Cdd:TIGR00606  473 ILELDQELRKAERELSKaEKNSLTETLKkevkSLQNEKADLDRKLRKLDQEMEQLNHHTttrtqmEMLTKDKMDKDEQIR 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2081 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLe 2160
Cdd:TIGR00606  553 KIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDV- 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2161 relqMSEENQElviLDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLL 2240
Cdd:TIGR00606  632 ----CGSQDEE---SDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKL 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2241 ----EEKEQAEIQIKEESKTAVEML------QNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSI---EKLR 2307
Cdd:TIGR00606  705 rlapDKLKSTESELKKKEKRRDEMLglapgrQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpeEESA 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2308 ARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSK--GEVETLKAKIEGMTQSLRGLEL 2385
Cdd:TIGR00606  785 KVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTvvSKIELNRKLIQDQQEQIQHLKS 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2386 DVVTIRSEKENLTNELQKEQERISELEIINSSfeniLQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACK 2465
Cdd:TIGR00606  865 KTNELKSEKLQIGTNLQRRQQFEEQLVELSTE----VQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQ 940

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2466 AKEQNLSSQVECLELEKAQLLQGLDEAKNNYIV-LQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQlvsklsqv 2544
Cdd:TIGR00606  941 DKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKqKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKI-------- 1012

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2545 egeHQLWKEQNLELRNLTVELEQKIQVLQSKNASL-QDTLEVLQSSYKNLENELELTKMDKmsfvekvNKMTAKETELQR 2623
Cdd:TIGR00606 1013 ---QERWLQDNLTLRKRENELKEVEEELKQHLKEMgQMQVLQMKQEHQKLEENIDLIKRNH-------VLALGRQKGYEK 1082

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 55770834   2624 EMHEMAQKTAELQEELSGEKNRLAgelqllLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKV 2692
Cdd:TIGR00606 1083 EIKHFKKELREPQFRDAEEKYREM------MIVMRTTELVNKDLDIYYKTLDQAIMKFHSMKMEEINKI 1145
PTZ00121 PTZ00121
MAEBL; Provisional
 2065-2691 4.94e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 4.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2065 KELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKE 2144
Cdd:PTZ00121 1268 RQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEA 1347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2145 RERENDSLKDKVENlerelqmSEENQELVILDAENSKAEVETLKTQIEEMARSlkvfeldlvtlrsekENLTKQIQEKQG 2224
Cdd:PTZ00121 1348 AKAEAEAAADEAEA-------AEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA---------------DEAKKKAEEDKK 1405

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2225 QLSELDKllssfkslleekeqaeiqiKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEqsLDPPIEEEHQLRNSIE 2304
Cdd:PTZ00121 1406 KADELKK-------------------AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADE--AKKKAEEAKKAEEAKK 1464

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2305 KLRARLEADEKKqlcvlqqlKESEHhadllKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRgle 2384
Cdd:PTZ00121 1465 KAEEAKKADEAK--------KKAEE-----AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK--- 1528

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2385 ldvvtiRSEKENLTNELQKEQERISELEIINSsfENILQEKEQEKVQMKEKSSTAMEMLQTQLKELnervaalhndQEAC 2464
Cdd:PTZ00121 1529 ------KAEEAKKADEAKKAEEKKKADELKKA--EELKKAEEKKKAEEAKKAEEDKNMALRKAEEA----------KKAE 1590

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2465 KAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSvngliQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVS-KLSQ 2543
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA-----EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKiKAAE 1665

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2544 VEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQssyknlENELELTKMDKMSFVEKVNKMTAKetELQR 2623
Cdd:PTZ00121 1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK------KEAEEKKKAEELKKAEEENKIKAE--EAKK 1737

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 55770834  2624 EMHEMAQKTAELQEElSGEKNRLAgelQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGK 2691
Cdd:PTZ00121 1738 EAEEDKKKAEEAKKD-EEEKKKIA---HLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1960-2407 7.29e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.16  E-value: 7.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1960 RNQLRGELDTMSKKTTALDQL-SEKMKEKTQELESHQSEclhciqvaEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQ 2038
Cdd:COG4717   48 LERLEKEADELFKPQGRKPELnLKELKELEEELKEAEEK--------EEEYAELQEELEELEEELEELEAELEELREELE 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2039 SLEKDSQALSLTK--CELENQIAQLNKEKELL---VKESESLQARLSESDYEKLNVSKALEAALVEKGEfalrlsSTQEE 2113
Cdd:COG4717  120 KLEKLLQLLPLYQelEALEAELAELPERLEELeerLEELRELEEELEELEAELAELQEELEELLEQLSL------ATEEE 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2114 VHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDA-----ENSKAEVETLK 2188
Cdd:COG4717  194 LQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAAllallGLGGSLLSLIL 273

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2189 TQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLS-------ELDKLLSSF-----------KSLLEEKEQAEIQI 2250
Cdd:COG4717  274 TIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAleeleeeELEELLAALglppdlspeelLELLDRIEELQELL 353

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2251 KEESKTAVEMLQNQLKELNEAVAALCG---DQEIMKATEQSldppiEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKES 2327
Cdd:COG4717  354 REAEELEEELQLEELEQEIAALLAEAGvedEEELRAALEQA-----EEYQELKEELEELEEQLEELLGELEELLEALDEE 428

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2328 EHHADLLKGRVENLERELEIARTNQEHAALEAENSK----GEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQK 2403
Cdd:COG4717  429 ELEEELEELEEELEELEEELEELREELAELEAELEQleedGELAELLQELEELKAELRELAEEWAALKLALELLEEAREE 508


                 ....
gi 55770834 2404 EQER 2407
Cdd:COG4717  509 YREE 512
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 420-988 7.41e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.33  E-value: 7.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  500 REVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLtLEKLKLAVADLEKQRDCSQDLLKKREH 579
Cdd:COG1196  316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL-LEAEAELAEAEEELEELAEELLEALRA 394

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  580 HIEQLNDKLSKTEKESKALLSALELKKKeyeelkeektlfscwKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSH 659
Cdd:COG1196  395 AAELAAQLEELEEAEEALLERLERLEEE---------------LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  660 EYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVE-----D 734
Cdd:COG1196  460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEaayeaA 539

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  735 LEHKLQLLSNEIMDKDRcyQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIgeqgsmpsersEC 814
Cdd:COG1196  540 LEAALAAALQNIVVEDD--EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV-----------AS 606

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  815 RLEADQSPKNSAILQNRVDSLEfsLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSA 894
Cdd:COG1196  607 DLREADARYYVLGDTLLGRTLV--AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  895 HQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQ 974
Cdd:COG1196  685 AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764

                        570
                 ....*....|....
gi 55770834  975 ENGTLKEINASLNQ 988
Cdd:COG1196  765 LERELERLEREIEA 778
mukB PRK04863
chromosome partition protein MukB;
2055-2355 9.60e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 54.96  E-value: 9.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2055 ENQIAQLNKEKELLVKESESLQARLS--ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEklrvRIEADE 2132
Cdd:PRK04863  785 EKRIEQLRAEREELAERYATLSFDVQklQRLHQAFSRFIGSHLAVAFEADPEAELRQLNRRRVELERALA----DHESQE 860

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2133 KKQLHIAEKLKERER------------ENDSLKDKVENLERELQMSEEN---------------QELVILDAENSkaEVE 2185
Cdd:PRK04863  861 QQQRSQLEQAKEGLSalnrllprlnllADETLADRVEEIREQLDEAEEAkrfvqqhgnalaqlePIVSVLQSDPE--QFE 938

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2186 TLK---TQIEEMARSLKVFELDLVTLRSEKENLTkqIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAvemlQ 2262
Cdd:PRK04863  939 QLKqdyQQAQQTQRDAKQQAFALTEVVQRRAHFS--YEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQA----Q 1012

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2263 NQLKELNEAVAALCGD----QEIMKATEQSLDP-----PIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADL 2333
Cdd:PRK04863 1013 AQLAQYNQVLASLKSSydakRQMLQELKQELQDlgvpaDSGAEERARARRDELHARLSANRSRRNQLEKQLTFCEAEMDN 1092

                         330       340
                  ....*....|....*....|..
gi 55770834  2334 LKGRVENLERELEIARTNQEHA 2355
Cdd:PRK04863 1093 LTKKLRKLERDYHEMREQVVNA 1114
COG5022 COG5022
Myosin heavy chain [General function prediction only];
845-1324 9.82e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.08  E-value: 9.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  845 MNSDLQKQCE-ELVQIKGEIEENLMKAEQMHQSFV--AETSQRISKLQEDTsahqnVVAETLSALENKEKELQLLNDKVE 921
Cdd:COG5022  818 CIIKLQKTIKrEKKLRETEEVEFSLKAEVLIQKFGrsLKAKKRFSLLKKET-----IYLQSAQRVELAERQLQELKIDVK 892

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  922 T--------EQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKemssiiSLNKREIEELTQENGTLKEINASLNQEKMNL 993
Cdd:COG5022  893 SisslklvnLELESEIIELKKSLSSDLIENLEFKTELIARLKK------LLNNIDLEEGPSIEYVKLPELNKLHEVESKL 966

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  994 IQKSESFANYIDEREKSISELSDQykQEKLILLQRceetgnAYEDLSQKYKAAQEKNSKLECLLNECTSLcenrKNELEQ 1073
Cdd:COG5022  967 KETSEEYEDLLKKSTILVREGNKA--NSELKNFKK------ELAELSKQYGALQESTKQLKELPVEVAEL----QSASKI 1034

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1074 LKEAFAKEHQefLTKLafaeernQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQEN 1153
Cdd:COG5022 1035 ISSESTELSI--LKPL-------QKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTN 1105

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1154 EQLmkvMKTKHECQNLESEPIRNSVKERESE--RNQCNFKPQM-------DLEVKEISLDSYNAQLVQLEAMLRNKELKL 1224
Cdd:COG5022 1106 RNL---VKPANVLQFIVAQMIKLNLLQEISKflSQLVNTLEPVfqklsvlQLELDGLFWEANLEALPSPPPFAALSEKRL 1182

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1225 QESEKEKEC---LQHELQTIRGDLETsnlqdMQSQEISGL-KDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQTTMNK- 1299
Cdd:COG5022 1183 YQSALYDEKsklSSSEVNDLKNELIA-----LFSKIFSGWpRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMs 1257

                        490       500       510
                 ....*....|....*....|....*....|..
gi 55770834 1300 -------LNELEKICEILQAEKYELVTELNDS 1324
Cdd:COG5022 1258 nekllslLNSIDNLLSSYKLEEEVLPATINSL 1289
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 410-1208 1.03e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    410 LDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMeemkkenn 489
Cdd:pfam15921  108 LRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMM-------- 179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    490 llKSHseqkarevchlEAELKNIKQCLnqsQNFAEEMKAKNTSQETMlrdlqekinqqeNSLTLEKLKLAVADLEKQRDC 569
Cdd:pfam15921  180 --LSH-----------EGVLQEIRSIL---VDFEEASGKKIYEHDSM------------STMHFRSLGSAISKILRELDT 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    570 SQDLLKKREHHIEqlnDKLSKTEKESKALLSALELKKKEYEELKEektlfscwkSENEKLLTQMESEKENLQSKINHLET 649
Cdd:pfam15921  232 EISYLKGRIFPVE---DQLEALKSESQNKIELLLQQHQDRIEQLI---------SEHEVEITGLTEKASSARSQANSIQS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    650 CLKTQQIKSHEYNE----RVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQ-KLAYMELQQKAEFSDQkhqkeienmclk 724
Cdd:pfam15921  300 QLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQlVLANSELTEARTERDQ------------ 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    725 TSQLTGQVEDLEHKLqllsneIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLlafDQQPAMHHSFANIIGEQ 804
Cdd:pfam15921  368 FSQESGNLDDQLQKL------LADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRREL---DDRNMEVQRLEALLKAM 438

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    805 GSMPSERSECRLEADQSpKNSAIlqNRVDSLEFSLESQKQMnsdLQKQCEELVQIKGEIE------ENLMKAEQMHQSFV 878
Cdd:pfam15921  439 KSECQGQMERQMAAIQG-KNESL--EKVSSLTAQLESTKEM---LRKVVEELTAKKMTLEssertvSDLTASLQEKERAI 512

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    879 AETSQRISKLQedtsAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLL-------SETL 951
Cdd:pfam15921  513 EATNAEITKLR----SRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLvgqhgrtAGAM 588

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    952 SLEKKEMSSIISLNKREIEELT----QENGTLKEINASLNQEKMNLIQksesFANYIDEREKSISELsdqyKQEKLILLQ 1027
Cdd:pfam15921  589 QVEKAQLEKEINDRRLELQEFKilkdKKDAKIRELEARVSDLELEKVK----LVNAGSERLRAVKDI----KQERDQLLN 660

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1028 RCEETGNAYEDLSQKYKAAQE----KNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQE--FLTKLAFAEERN----Q 1097
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLKRnfrnKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSdgHAMKVAMGMQKQitakR 740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1098 NLMLELETVQQALRSEMTDNQNNS---KSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQL------MKVMKTKHECQN 1168
Cdd:pfam15921  741 GQIDALQSKIQFLEEAMTNANKEKhflKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLkekvanMEVALDKASLQF 820

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 55770834   1169 LESEPIRNSvKERESERnqcnFKPQMDLEVKEISLDSYNA 1208
Cdd:pfam15921  821 AECQDIIQR-QEQESVR----LKLQHTLDVKELQGPGYTS 855
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1787-2272 1.03e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1787 LHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGL 1866
Cdd:TIGR04523  175 LNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1867 NSDLEMHADK-----SSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNEN 1941
Cdd:TIGR04523  255 LNQLKDEQNKikkqlSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNN 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1942 KQ-----KVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELL 2016
Cdd:TIGR04523  335 KIisqlnEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQI 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2017 QTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAA 2096
Cdd:TIGR04523  415 KKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2097 LVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKD--KVENLERELQMSEENQELVI 2174
Cdd:TIGR04523  495 EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFelKKENLEKEIDEKNKEIEELK 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2175 LDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEES 2254
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654

                          490
                   ....*....|....*...
gi 55770834   2255 KTAVEMLQNQLKELNEAV 2272
Cdd:TIGR04523  655 KEIRNKWPEIIKKIKESK 672
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 20-362 1.06e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 1.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   20 IQELEGQLDKLKKEKQQ-----------RQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISH 88
Cdd:COG1196  195 LGELERQLEPLERQAEKaeryrelkeelKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   89 ELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLnpcntpqkifttpltpsqyysgskyEDLK 168
Cdd:COG1196  275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL-------------------------AELE 329

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  169 EKYNKEVEERKRLEAEVKALQAKKASQtlpQATMNHRDIARHQASSSVFSWQQEktpshlssnsqrtpiRRDFSASYFSG 248
Cdd:COG1196  330 EELEELEEELEELEEELEEAEEELEEA---EAELAEAEEALLEAEAELAEAEEE---------------LEELAEELLEA 391

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  249 EQEVTPSRSTLQIGKRDANSSFFdnsssphLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVE 328
Cdd:COG1196  392 LRAAAELAAQLEELEEAEEALLE-------RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                        330       340       350
                 ....*....|....*....|....*....|....
gi 55770834  329 LIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ 362
Cdd:COG1196  465 LAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2417-2885 1.53e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 1.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2417 SFENILQEKEQEKVQMKEKsstaMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNY 2496
Cdd:TIGR04523   23 GYKNIANKQDTEEKQLEKK----LKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKI 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2497 IVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSK-LSQVEGEHQLWKEQNLELRNLTVELEQkiqvLQSK 2575
Cdd:TIGR04523   99 NKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKfLTEIKKKEKELEKLNNKYNDLKKQKEE----LENE 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2576 NASLQDTLEVLQSSYKNLENELeLTKMDKMSFVEKVNKmtaKETELQREMHEMAQKTAELQEELSGEKNrlagELQLLLE 2655
Cdd:TIGR04523  175 LNLLEKEKLNIQKNIDKIKNKL-LKLELLLSNLKKKIQ---KNKSLESQISELKKQNNQLKDNIEKKQQ----EINEKTT 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2656 EIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVRE---EIAEYQLRLHEAEKKHQAlllDTNKQYEVEIQTYREKL 2732
Cdd:TIGR04523  247 EISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKElekQLNQLKSEISDLNNQKEQ---DWNKELKSELKNQEKKL 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2733 TSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEeekeil 2812
Cdd:TIGR04523  324 EEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE------ 397

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 55770834   2813 QKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQV 2885
Cdd:TIGR04523  398 SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL 470
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 879-1155 1.67e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  879 AETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLslekkem 958
Cdd:COG1196  242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL------- 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  959 ssiislnKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYED 1038
Cdd:COG1196  315 -------EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1039 LSQKYKAAQEKNSKLECLLNECTSLcENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEmTDNQ 1118
Cdd:COG1196  388 LLEALRAAAELAAQLEELEEAEEAL-LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL-LELL 465

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 55770834 1119 NNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQ 1155
Cdd:COG1196  466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1787-2857 2.17e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 53.64  E-value: 2.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1787 LHVIEDRDRKVESLLNEMKE-----LDSKLHLQEvQLMTKIEACIELEKIVGELKKENSDLSEKLeyfscdhQELLQRVE 1861
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKkhqqlCEEKNALQE-QLQAETELCAEAEEMRARLAARKQELEEIL-------HELESRLE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1862 TSEGLNSDLEMHADKssredigdnvakvndsWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNEN 1941
Cdd:pfam01576   86 EEEERSQQLQNEKKK----------------MQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSK 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1942 KQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSS 2021
Cdd:pfam01576  150 LSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQA 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2022 DVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKg 2101
Cdd:pfam01576  230 QIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL- 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2102 EFALRLSSTQEEVHQlRRGIEKLRVRIEADEKKQLHIAEKLKEREREN---DSLKDKVENLERELQMSEENQELVILDAE 2178
Cdd:pfam01576  309 EDTLDTTAAQQELRS-KREQEVTELKKALEEETRSHEAQLQEMRQKHTqalEELTEQLEQAKRNKANLEKAKQALESENA 387

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2179 NSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAV 2258
Cdd:pfam01576  388 ELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLE 467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2259 EMLQNQLKELNEAVAALCGDQEIMKATEqsldppiEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRV 2338
Cdd:pfam01576  468 SQLQDTQELLQEETRQKLNLSTRLRQLE-------DERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTL 540

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2339 ENLErelEIARTNQEhaaleaenskgEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSF 2418
Cdd:pfam01576  541 EALE---EGKKRLQR-----------ELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKF 606

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2419 ENILQEKEQEKVQMKEKSSTAmemlQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIV 2498
Cdd:pfam01576  607 DQMLAEEKAISARYAEERDRA----EAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHE 682

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2499 LQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKL-SQVEGEHQLWKEQNLELRNLTV----ELEQKIQVLQ 2573
Cdd:pfam01576  683 LERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALkAQFERDLQARDEQGEEKRRQLVkqvrELEAELEDER 762

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2574 SKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAEL---QEELSGEKNRLAGEL 2650
Cdd:pfam01576  763 KQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEIlaqSKESEKKLKNLEAEL 842

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2651 QLLLEEIKSSKDQLKELTLENSELKKSLDCMHKD---QVEKEGKVREEIAEYQLRLHEaEKKHQALLLDTNKQYEVEIQT 2727
Cdd:pfam01576  843 LQLQEDLAASERARRQAQQERDELADEIASGASGksaLQDEKRRLEARIAQLEEELEE-EQSNTELLNDRLRKSTLQVEQ 921

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2728 YREKLTSkeECLSSQKLEIDllKSSKEELNNSLKATTQILEELKKTKMDN---------LKYVNQLKKENERAQGKMKLL 2798
Cdd:pfam01576  922 LTTELAA--ERSTSQKSESA--RQQLERQNKELKAKLQEMEGTVKSKFKSsiaaleakiAQLEEQLEQESRERQAANKLV 997

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 55770834   2799 IKSCKQLEEEkeILQKELSQLQAAQEKQKtgtvmdtkVDELTTEIKELKETLEEKTKEA 2857
Cdd:pfam01576  998 RRTEKKLKEV--LLQVEDERRHADQYKDQ--------AEKGNSRMKQLKRQLEEAEEEA 1046
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1914-2666 2.36e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.69  E-value: 2.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1914 IEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKK--------TTALDQLSEKMK 1985
Cdd:pfam12128  239 IRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQwkekrdelNGELSAADAAVA 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1986 EKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQAL-SLTKCELENQIAQLNKE 2064
Cdd:pfam12128  319 KDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRrSKIKEQNNRDIAGIKDK 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2065 KELlVKESESLQARLSESDYEklnvskALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVrieadekKQLHIAEKLKE 2144
Cdd:pfam12128  399 LAK-IREARDRQLAVAEDDLQ------ALESELREQLEAGKLEFNEEEYRLKSRLGELKLRL-------NQATATPELLL 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2145 RERENDSLKDKVenleRELQmseenqelvildaENSKAEVETLktqieemarslkvfELDLVTLRSEKENLTKQIQEKQG 2224
Cdd:pfam12128  465 QLENFDERIERA----REEQ-------------EAANAEVERL--------------QSELRQARKRRDQASEALRQASR 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2225 QLSELDKLLssfkslleekEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCgDQEIMKATEqsLDPPIEEEHQL-RNSI 2303
Cdd:pfam12128  514 RLEERQSAL----------DELELQLFPQAGTLLHFLRKEAPDWEQSIGKVI-SPELLHRTD--LDPEVWDGSVGgELNL 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2304 EKLRARLEAdekkqlcvlQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGL 2383
Cdd:pfam12128  581 YGVKLDLKR---------IDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNA 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2384 ELDvvtirsekenltnelqkeQERISEleiinssfenilqEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEA 2463
Cdd:pfam12128  652 RLD------------------LRRLFD-------------EKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQA 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2464 CKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIV-----LQSSVNGLIQEVE-DGKQKLEKKD---EEISRLKNQIQDQ 2534
Cdd:pfam12128  701 WLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKaaiaaRRSGAKAELKALEtWYKRDLASLGvdpDVIAKLKREIRTL 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2535 EQLVSKLSQVEGE----HQLWKEQNLELRnltveleqkiQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK 2610
Cdd:pfam12128  781 ERKIERIAVRRQEvlryFDWYQETWLQRR----------PRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKA 850

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834   2611 VNKMTAKETELQREMHEMAQKTAELQEELSGEKNRL-AGELQLLLEEIKSSKDQLKE 2666
Cdd:pfam12128  851 SEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGsIGERLAQLEDLKLKRDYLSE 907
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 2355-2894 3.21e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.05  E-value: 3.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2355 AALEAENSKgeveTLKAKIEGMTQSLRGLELD----VVTIRSEKENLTNELQKEQERISELEIINSSFEnilqeKEQEKV 2430
Cdd:TIGR00618  182 ALMEFAKKK----SLHGKAELLTLRSQLLTLCtpcmPDTYHERKQVLEKELKHLREALQQTQQSHAYLT-----QKREAQ 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2431 QMKEKSSTAMEMLQTQLKELNERVAALHNDQEackakEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEV 2510
Cdd:TIGR00618  253 EEQLKKQQLLKQLRARIEELRAQEAVLEETQE-----RINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2511 EDGK--QKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLE---- 2584
Cdd:TIGR00618  328 MKRAahVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDilqr 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2585 -------------VLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGElq 2651
Cdd:TIGR00618  408 eqatidtrtsafrDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQE-- 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2652 lllEEIKSSKDQLKELTLENS-ELKKSldCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYRE 2730
Cdd:TIGR00618  486 ---TRKKAVVLARLLELQEEPcPLCGS--CIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRAS 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2731 KLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQIL----EELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLE 2806
Cdd:TIGR00618  561 LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQdlteKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQE 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2807 EEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDK---YCSLLIS--HEKLEKAKEML 2881
Cdd:TIGR00618  641 LALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEmlaQCQTLLRelETHIEEYDREF 720

                          570
                   ....*....|...
gi 55770834   2882 ETQVAHLCSQQSK 2894
Cdd:TIGR00618  721 NEIENASSSLGSD 733
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2033-2500 3.64e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.85  E-value: 3.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2033 LQEKLQSLEKDS-QALSLTKCELENQIAQLnKEKELLVKESESLQARLSESDYEKLNVSKALEAA--LVEKGEFALRLSS 2109
Cdd:COG4717   51 LEKEADELFKPQgRKPELNLKELKELEEEL-KEAEEKEEEYAELQEELEELEEELEELEAELEELreELEKLEKLLQLLP 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2110 TQEEVHQLRRGIEKLRVRIEADEKKQlhiaEKLKERERENDSLKDKVENLERELqmseenQELVILDAENSKAEVETLKT 2189
Cdd:COG4717  130 LYQELEALEAELAELPERLEELEERL----EELRELEEELEELEAELAELQEEL------EELLEQLSLATEEELQDLAE 199

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2190 QIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2269
Cdd:COG4717  200 ELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVL 279

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLR--------ARLEADEKKQLCVLQQLKESEHHADLLKGRVENL 2341
Cdd:COG4717  280 FLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEeeeleellAALGLPPDLSPEELLELLDRIEELQELLREAEEL 359

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2342 ERELEIARTNQEHAALEAENSKGEVETLKAKIEgmtqslrgleldvvtIRSEKENLTNELQKEQERISEleiINSSFENI 2421
Cdd:COG4717  360 EEELQLEELEQEIAALLAEAGVEDEEELRAALE---------------QAEEYQELKEELEELEEQLEE---LLGELEEL 421

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2422 LQEKEQEKVQMKEKSstamemLQTQLKELNERVAALHNDQEACKAKEQNLSSQ--VECLELEKAQLLQGLDEAKNNYIVL 2499
Cdd:COG4717  422 LEALDEEELEEELEE------LEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQELEELKAELRELAEEWAAL 495


                 .
gi 55770834 2500 Q 2500
Cdd:COG4717  496 K 496
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2355-2598 4.91e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 4.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2355 AALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKE 2434
Cdd:COG4942   11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2435 KSSTAMEMLQTQLKELNERVAALHndqeackakeqnLSSQVECLELEKAQllQGLDEAKNNYIVLQSSVNGLIQEVEDGK 2514
Cdd:COG4942   91 EIAELRAELEAQKEELAELLRALY------------RLGRQPPLALLLSP--EDFLDAVRRLQYLKYLAPARREQAEELR 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2515 QKLEKKDEEISRLKNQIQDQEQLVSKLsqvegehqlwKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLE 2594
Cdd:COG4942  157 ADLAELAALRAELEAERAELEALLAEL----------EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226


                 ....
gi 55770834 2595 NELE 2598
Cdd:COG4942  227 ALIA 230
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2650-2888 5.12e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 5.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2650 LQLLLEEIKSSKDQLK----------ELTLENSELKKSLDCMHKDQVEKE-GKVREEIAEYQLRLHEAEKKHQALlldtn 2718
Cdd:COG1196  191 LEDILGELERQLEPLErqaekaeryrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAEL----- 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2719 kqyEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLL 2798
Cdd:COG1196  266 ---EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2799 IKSCKQLEEEKEILQKELSQLQAAQEKQKtgtvmdTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAK 2878
Cdd:COG1196  343 EEELEEAEEELEEAEAELAEAEEALLEAE------AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416

                        250
                 ....*....|
gi 55770834 2879 EMLETQVAHL 2888
Cdd:COG1196  417 ERLEEELEEL 426
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 2327-2898 5.68e-06

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 52.13  E-value: 5.68e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2327 SEHHADLLKGRVENLERELEIARTNQEHAALEAENSKgevETLKAKIEgmtqSLRGLeLDVVTIRSEKENLTNELQKEQE 2406
Cdd:pfam10174  114 TEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQK---QTLGARDE----SIKKL-LEMLQSKGLPKKSGEEDWERTR 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2407 RISELEIINSSFENILQEKEQEKVQMKEKSSTamemlQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELE----K 2482
Cdd:pfam10174  186 RIAEAEMQLGHLEVLLDQKEKENIHLREELHR-----RNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEvqmlK 260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2483 AQLLQGLDEAKNNYI---VLQSSVNGLIQEVEDGKQKLEKKDEEI-------SRLKNQIQDQEQLVSKLSqvegEHQLWK 2552
Cdd:pfam10174  261 TNGLLHTEDREEEIKqmeVYKSHSKFMKNKIDQLKQELSKKESELlalqtklETLTNQNSDCKQHIEVLK----ESLTAK 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2553 EQ-----NLELRNLTVELEQKIQVLQSKNASLQDTLE---VLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQRE 2624
Cdd:pfam10174  337 EQraailQTEVDALRLRLEEKESFLNKKTKQLQDLTEeksTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQ 416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2625 MHEMAQKTAELQ-------------EELSGEKNRLAGELQLLLE-EIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEG 2690
Cdd:pfam10174  417 LAGLKERVKSLQtdssntdtalttlEEALSEKERIIERLKEQRErEDRERLEELESLKKENKDLKEKVSALQPELTEKES 496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2691 KVREEIAEYQLRLHEAEKKHQALlldtnKQYEVEIQTyrekltSKEECLssqKLEIDLLKSSKEELNNslKATTQILEEL 2770
Cdd:pfam10174  497 SLIDLKEHASSLASSGLKKDSKL-----KSLEIAVEQ------KKEECS---KLENQLKKAHNAEEAV--RTNPEINDRI 560

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2771 KKTKMDnlkyVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQ-KTGTVMDTKVDELTTEI-KELKE 2848
Cdd:pfam10174  561 RLLEQE----VARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQmKEQNKKVANIKHGQQEMkKKGAQ 636

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 55770834   2849 TLEEKTKEADEYLDKYCSLLISH--EKLEKAKEMLETQVAHLCSQQSKQDSR 2898
Cdd:pfam10174  637 LLEEARRREDNLADNSQQLQLEElmGALEKTRQELDATKARLSSTQQSLAEK 688
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2271-2484 5.79e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 5.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2271 AVAALCGDQEIMKATEQSLDppieeehQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL----- 2345
Cdd:COG4942   11 LALAAAAQADAAAEAEAELE-------QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELaalea 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2346 EIARTNQEHAALEAE-----------------NSKGEVETLKAKIEGMTQSLRGLELdVVTIRSEKENLTNELQKEQERI 2408
Cdd:COG4942   84 ELAELEKEIAELRAEleaqkeelaellralyrLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAEL 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 55770834 2409 SELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQ 2484
Cdd:COG4942  163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
809-1235 6.64e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.99  E-value: 6.64e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   809 SERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQsfVAETSQRISKL 888
Cdd:PRK03918  238 EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEE--YLDELREIEKR 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   889 QEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLkelQLLSETLSLEKKEMSSIISLNKRE 968
Cdd:PRK03918  316 LSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK---AKKEELERLKKRLTGLTPEKLEKE 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   969 IEELTQENGTLKEINASLNQEKMNLIQKsesfanyIDEREKSISELSdqyKQEKLILLQRCEETGNAYEDLSQKYKAaqe 1048
Cdd:PRK03918  393 LEELEKAKEEIEEEISKITARIGELKKE-------IKELKKAIEELK---KAKGKCPVCGRELTEEHRKELLEEYTA--- 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1049 KNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQefLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGL 1128
Cdd:PRK03918  460 ELKRIEKELKEIEEKERKLRKELRELEKVLKKESE--LIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKL 537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1129 KQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCN---------FKPQMDLEVK 1199
Cdd:PRK03918  538 KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEpfyneylelKDAEKELERE 617

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 55770834  1200 EISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQ 1235
Cdd:PRK03918  618 EKELKKLEEELDKAFEELAETEKRLEELRKELEELE 653
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2422-2611 6.78e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.94  E-value: 6.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2422 LQEKEQEKVQMKEKS-----STAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQ--GLDEAKN 2494
Cdd:COG3206  191 LEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQspVIQQLRA 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2495 NYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVskLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQS 2574
Cdd:COG3206  271 QLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI--LASLEAELEALQAREASLQAQLAQLEARLAELPE 348

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 55770834 2575 KNA---SLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2611
Cdd:COG3206  349 LEAelrRLEREVEVARELYESLLQRLEEARLAEALTVGNV 388
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2212-2636 7.18e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 7.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2212 KENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEesktavemLQNQLKELNEAVAALcgdqeimkATEQSLDP 2291
Cdd:COG4717   66 PELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEE--------LEAELEELREELEKL--------EKLLQLLP 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2292 PIEEEHQLRNSIEKLRARLEADEKKqlcvLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEA-ENSKGEVETLK 2370
Cdd:COG4717  130 LYQELEALEAELAELPERLEELEER----LEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQ 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2371 AKIEGMTQSLRGLELDVVTIRSEKENLTNEL--QKEQERISELEIINSSFeNILQEKEQEKVQMKEKSSTAMEMLQTQLK 2448
Cdd:COG4717  206 QRLAELEEELEEAQEELEELEEELEQLENELeaAALEERLKEARLLLLIA-AALLALLGLGGSLLSLILTIAGVLFLVLG 284

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2449 ELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLK 2528
Cdd:COG4717  285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2529 --------------NQIQDQEQLVSKLSQVEGEHQL---WKEQNLELRNL------------TVELEQKIQVLQSKNASL 2579
Cdd:COG4717  365 leeleqeiaallaeAGVEDEEELRAALEQAEEYQELkeeLEELEEQLEELlgeleellealdEEELEEELEELEEELEEL 444

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834 2580 QDTLEVLQSSYKNLENELELTKMDkmsfvEKVNKMTAKETELQREMHEMAQKTAELQ 2636
Cdd:COG4717  445 EEELEELREELAELEAELEQLEED-----GELAELLQELEELKAELRELAEEWAALK 496
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2441-2860 7.88e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 7.88e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2441 EMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVEclELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKK 2520
Cdd:COG4717   67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEE--ELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAEL 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2521 DEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLT---------------VELEQKIQVLQSKNASLQDTLEV 2585
Cdd:COG4717  145 PERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLslateeelqdlaeelEELQQRLAELEEELEEAQEELEE 224

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2586 LQSSYKNLENELELTKMDK-----------MSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLL 2654
Cdd:COG4717  225 LEEELEQLENELEAAALEErlkearlllliAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2655 EEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDtnkQYEVEIQTYREKLTS 2734
Cdd:COG4717  305 EELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE---ELEQEIAALLAEAGV 381

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2735 KEECLSSQKLEIdllKSSKEELNNSLKATTQILEELKKTKMDNLKYVN--QLKKENERAQGKMKLLIKSCKQLEEEKEIL 2812
Cdd:COG4717  382 EDEEELRAALEQ---AEEYQELKEELEELEEQLEELLGELEELLEALDeeELEEELEELEEELEELEEELEELREELAEL 458

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*...
gi 55770834 2813 QKELSQLQAaqekqktgtvmDTKVDELTTEIKELKETLEEKTKEADEY 2860
Cdd:COG4717  459 EAELEQLEE-----------DGELAELLQELEELKAELRELAEEWAAL 495
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2225-2496 8.63e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 8.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2225 QLSELDKLLSSFksLLEEKEqaeiqikeeSKTAVEMLQNQLKELNEAvaalcgDQEIMKATEQ--SLDPpIEEEHQlrns 2302
Cdd:COG4913  205 PIGDLDDFVREY--MLEEPD---------TFEAADALVEHFDDLERA------HEALEDAREQieLLEP-IRELAE---- 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2303 iEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELeiARTNQEHAALEAenskgEVETLKAKIEGMTQSLRG 2382
Cdd:COG4913  263 -RYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAEL--ARLEAELERLEA-----RLDALREELDELEAQIRG 334

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2383 LELDvvtirsEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQE 2462
Cdd:COG4913  335 NGGD------RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALA 408

                        250       260       270
                 ....*....|....*....|....*....|....
gi 55770834 2463 ACKAKEQNLSSQVECLELEKAQLLQGldeaKNNY 2496
Cdd:COG4913  409 EAEAALRDLRRELRELEAEIASLERR----KSNI 438
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 2393-2859 8.67e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 51.65  E-value: 8.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2393 EKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLS 2472
Cdd:pfam05483  280 QDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTC 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2473 SQVECLELEKAQLLQGLDEAKNNYIVLQSSVNgliqEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWK 2552
Cdd:pfam05483  360 SLEELLRTEQQRLEKNEDQLKIITMELQKKSS----ELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELK 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2553 EQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKT 2632
Cdd:pfam05483  436 GKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLEL 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2633 AELQEELSGEKNR-----------------LAGELQLLLEEIKSSKDQLKeLTLENSELKKSLDCMHKDQVEKEGKVREE 2695
Cdd:pfam05483  516 KKHQEDIINCKKQeermlkqienleekemnLRDELESVREEFIQKGDEVK-CKLDKSEENARSIEYEVLKKEKQMKILEN 594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2696 IAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQI--------L 2767
Cdd:pfam05483  595 KCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDkkiseeklL 674

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2768 EELKKTKMDNLKYVNQLKKENERAQGKM----KLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTV-MDTKVDELTTE 2842
Cdd:pfam05483  675 EEVEKAKAIADEAVKLQKEIDKRCQHKIaemvALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAaLEIELSNIKAE 754

                          490
                   ....*....|....*..
gi 55770834   2843 IKELKETLEEKTKEADE 2859
Cdd:pfam05483  755 LLSLKKQLEIEKEEKEK 771
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 280-502 8.95e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 8.95e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Cdd:COG4942   22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  360 LEQKLKKLTeDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL 439
Cdd:COG4942  102 QKEELAELL-RALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 55770834  440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREV 502
Cdd:COG4942  181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 879-1114 9.02e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 9.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  879 AETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEM 958
Cdd:COG4942   23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  959 SSIISLNKREIeeltQENGTLKEINASLNQEKMNLIQKSesfANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYED 1038
Cdd:COG4942  103 KEELAELLRAL----YRLGRQPPLALLLSPEDFLDAVRR---LQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 55770834 1039 LSQKYKAAQEKNSKLECLLNEctslcenRKNELEQLKEAFAKEHQEfLTKLAFAEERNQNLMLELETVQQALRSEM 1114
Cdd:COG4942  176 LEALLAELEEERAALEALKAE-------RQKLLARLEKELAELAAE-LAELQQEAEELEALIARLEAEAAAAAERT 243
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1827-2412 1.10e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 51.62  E-value: 1.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1827 ELEKIVGELKKENSDLSEKLEYFSCDHQELLQRV-ETSEGLNSDLEMHADKSSR-EDIGDNVAKVNDSWKErfLDVENEL 1904
Cdd:COG5022  879 LAERQLQELKIDVKSISSLKLVNLELESEIIELKkSLSSDLIENLEFKTELIARlKKLLNNIDLEEGPSIE--YVKLPEL 956

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1905 SRIRSEKASIehealyleadlevvqtEKLCLEKDNENKQKVIvcLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKM 1984
Cdd:COG5022  957 NKLHEVESKL----------------KETSEEYEDLLKKSTI--LVREGNKANSELKNFKKELAELSKQYGALQESTKQL 1018

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1985 KEKTQELESHQSEcLHCIQVAEAEVKEKTEllqtLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKE 2064
Cdd:COG5022 1019 KELPVEVAELQSA-SKIISSESTELSILKP----LQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLL 1093

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2065 KELLVKESESLQARL-SESDYEKLNVSKALEAALV-EKGEFALRLSSTQEEVHQLRRGIEKLR--VRIEADEKKQLHI-- 2138
Cdd:COG5022 1094 KTINVKDLEVTNRNLvKPANVLQFIVAQMIKLNLLqEISKFLSQLVNTLEPVFQKLSVLQLELdgLFWEANLEALPSPpp 1173

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2139 -AEKLKERERENDSLKDKVENLERELQM-SEENQELVILDAENSKAEVETLKTQIEEMarslkvfeLDLVTLRSEKENLT 2216
Cdd:COG5022 1174 fAALSEKRLYQSALYDEKSKLSSSEVNDlKNELIALFSKIFSGWPRGDKLKKLISEGW--------VPTEYSTSLKGFNN 1245

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2217 KQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEE 2296
Cdd:COG5022 1246 LNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKSATEVNYNSEELDD 1325

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2297 HQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLK-------GRVENLERELEIArtNQEHAALEAENSKGEVETL 2369
Cdd:COG5022 1326 WCREFEISDVDEELEELIQAVKVLQLLKDDLNKLDELLDacyslnpAEIQNLKSRYDPA--DKENNLPKEILKKIEALLI 1403

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|....*.
gi 55770834 2370 KAKIEGMTQSLRGLELDVVTIRSEKEN---LTNELQKEQERISELE 2412
Cdd:COG5022 1404 KQELQLSLEGKDETEVHLSEIFSEEKSlisLDRNSIYKEEVLSSLS 1449
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1766-2194 1.34e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 1.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1766 QEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1846 LEyfscdhqellqrvetseglnsDLEMHadkssREDIGDNVAKVNDSWKERFLDVENELSRIRsekasiEHEALyleadl 1925
Cdd:PRK02224  407 LG---------------------NAEDF-----LEELREERDELREREAELEATLRTARERVE------EAEAL------ 448

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1926 evvQTEKLCLEKDNENKQKVIVCL----EEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEkTQELESHQSECLHC 2001
Cdd:PRK02224  449 ---LEAGKCPECGQPVEGSPHVETieedRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR-IERLEERREDLEEL 524

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS- 2080
Cdd:PRK02224  525 IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADa 604

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2081 ESDYEKLNVSKALEAALVEkgEFALRLSSTQEEVHQLRRG-----IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDK 2155
Cdd:PRK02224  605 EDEIERLREKREALAELND--ERRERLAEKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREERDDLQAE 682

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 55770834  2156 VENLERELQMSEENQELviLDA-ENSKAEVETLKTQIEEM 2194
Cdd:PRK02224  683 IGAVENELEELEELRER--REAlENRVEALEALYDEAEEL 720
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2215-2439 1.44e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.79  E-value: 1.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2215 LTKQIQEKQGQLSELDKLLSSFKslleeKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIE 2294
Cdd:COG3206  180 LEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPD 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2295 EEHQLRNS--IEKLRARLEADEKKqlcvLQQLKE--SEHHADL--LKGRVENLERELEiARTNQEHAALEAEnskgeVET 2368
Cdd:COG3206  255 ALPELLQSpvIQQLRAQLAELEAE----LAELSAryTPNHPDViaLRAQIAALRAQLQ-QEAQRILASLEAE-----LEA 324

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 55770834 2369 LKAKIEGMTQSLRGLELDVVTIrsekenltNELQKEQERIS-ELEIINSSFENILQEKEQEKVQMKEKSSTA 2439
Cdd:COG3206  325 LQAREASLQAQLAQLEARLAEL--------PELEAELRRLErEVEVARELYESLLQRLEEARLAEALTVGNV 388
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1940-2129 1.48e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 1.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1940 ENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEkMKEKTQELESHQSEclhciqVAEAEvKEKTELLQTl 2019
Cdd:COG4913  613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE-YSWDEIDVASAERE------IAELE-AELERLDAS- 683

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2020 SSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNvsKALEAALVE 2099
Cdd:COG4913  684 SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE--ERFAAALGD 761

                        170       180       190
                 ....*....|....*....|....*....|
gi 55770834 2100 KGEFALRlSSTQEEVHQLRRGIEKLRVRIE 2129
Cdd:COG4913  762 AVERELR-ENLEERIDALRARLNRAEEELE 790
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
425-949 1.53e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 1.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   425 LQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE---QKARE 501
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEeieELEKE 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   502 VCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLK-----------LAVADLEKQRDCS 570
Cdd:PRK03918  247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYeeyldelreieKRLSRLEEEINGI 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   571 QDLLKKREH---HIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSEN----EKLLTQMESEKENLQSK 643
Cdd:PRK03918  327 EERIKELEEkeeRLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTpeklEKELEELEKAKEEIEEE 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   644 INHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHN----------VLDSKSVEVETQKLAYMELQQKAEFSDQK 713
Cdd:PRK03918  407 ISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEehrkelleeyTAELKRIEKELKEIEEKERKLRKELRELE 486

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   714 HQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKD-RCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAF----D 788
Cdd:PRK03918  487 KVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKaEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELekklD 566

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   789 QQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAI-LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENL 867
Cdd:PRK03918  567 ELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLeLKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELR 646

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   868 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLL 947
Cdd:PRK03918  647 KELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEEL 726


                  ..
gi 55770834   948 SE 949
Cdd:PRK03918  727 RE 728
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 280-768 1.77e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 1.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Cdd:TIGR04523  206 LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    360 LEQKLKKLTEDLSCQRQNAESarcsleqkikEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNmhnvLQAEL 439
Cdd:TIGR04523  286 LEKQLNQLKSEISDLNNQKEQ----------DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ----LKKEL 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    440 DKLTSVKQQLENNLEEFKQKLcraeqafqASQIKENE-LRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQ 518
Cdd:TIGR04523  352 TNSESENSEKQRELEEKQNEI--------EKLKKENQsYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    519 SQNFAEEMKAKNTSQETMLRDLQEKINQQEnsLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKAL 598
Cdd:TIGR04523  424 LEKEIERLKETIIKNNSEIKDLTNQDSVKE--LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    599 LSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKS--HEYNERVRTLEMDRENLS 676
Cdd:TIGR04523  502 NEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKeiDEKNKEIEELKQTQKSLK 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    677 VEIRNLHNVLDSKSVEVETQKlaymelqqkaefsdqkhqKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDL 756
Cdd:TIGR04523  582 KKQEEKQELIDQKEKEKKDLI------------------KEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643

                          490
                   ....*....|..
gi 55770834    757 HAEYESLRDLLK 768
Cdd:TIGR04523  644 KQEVKQIKETIK 655
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2480-2707 2.07e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 2.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2480 LEKAQLLQGLDEAKNNYIVLqssvNGLIQEVEDGKQKLE------KKDEEISRLKNQIQDQEQLVSKLSQVEGEH--QLW 2551
Cdd:COG4913  218 LEEPDTFEAADALVEHFDDL----ERAHEALEDAREQIEllepirELAERYAAARERLAELEYLRAALRLWFAQRrlELL 293

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2552 KEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSY---------------KNLENELELTKMDKMSFVEKVNKMTA 2616
Cdd:COG4913  294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIrgnggdrleqlereiERLERELEERERRRARLEALLAALGL 373

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2617 KETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEkegkVREEI 2696
Cdd:COG4913  374 PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLA----LRDAL 449

                        250
                 ....*....|.
gi 55770834 2697 AEyQLRLHEAE 2707
Cdd:COG4913  450 AE-ALGLDEAE 459
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1902-2134 2.29e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1902 NELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKttaLDQLS 1981
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE---IAELR 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1982 EKMKEKTQELEShqseclhciQVAEAEVKEKTELLQTL--SSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIA 2059
Cdd:COG4942   97 AELEAQKEELAE---------LLRALYRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55770834 2060 QLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKK 2134
Cdd:COG4942  168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2320-2476 2.30e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 48.38  E-value: 2.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2320 VLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKE--NL 2397
Cdd:COG1579   15 LDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyeAL 94

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 55770834 2398 TNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVE 2476
Cdd:COG1579   95 QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIP 173
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1766-2268 3.28e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.94  E-value: 3.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1766 QEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Cdd:COG1196  287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1846 LEYfscDHQELLQRVETSEGLNSDLEMHADKSSREDIG-DNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEAD 1924
Cdd:COG1196  367 LLE---AEAELAEAEEELEELAEELLEALRAAAELAAQlEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1925 LEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQ------ELESHQSEC 1998
Cdd:COG1196  444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvkaalLLAGLRGLA 523

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1999 LHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTkcelenqIAQLNKEKELLVKESESLQAR 2078
Cdd:COG1196  524 GAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT-------FLPLDKIRARAALAAALARGA 596

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2079 LSEsdyeklnVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVEN 2158
Cdd:COG1196  597 IGA-------AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2159 LERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKS 2238
Cdd:COG1196  670 LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749

                        490       500       510
                 ....*....|....*....|....*....|
gi 55770834 2239 LLEEKEQAEIQIKEESKTAVEMLQNQLKEL 2268
Cdd:COG1196  750 EEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 918-1184 3.50e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 3.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    918 DKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEInasLNQEKMNLIQKS 997
Cdd:TIGR02169  674 AELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER---LEELEEDLSSLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    998 ESFANYIDEREKSISELsdQYKQEKLILLQrcEETGNAYEDLSQ--------KYKAAQEKNSKLECLLNEctslCENRKN 1069
Cdd:TIGR02169  751 QEIENVKSELKELEARI--EELEEDLHKLE--EALNDLEARLSHsripeiqaELSKLEEEVSRIEARLRE----IEQKLN 822

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1070 ELEQLKEAFAKEHQEFLTKLAFAEER---NQNLMLELETVQQALRSEMTDNQNNSK---SEAGGLKQEIMTLKEEQNKMQ 1143
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIDLKEQiksIEKEIENLNGKKEELEEELEELEAALRdleSRLGDLKKERDELEAQLRELE 902

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 55770834   1144 KEVNDL---LQENEQLMKVMKTKHECQNLESEPIRNSVKERESE 1184
Cdd:TIGR02169  903 RKIEELeaqIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI 946
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1936-2363 3.61e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 3.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1936 EKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALD------QLSEKMKEKTQELESHQSEcLHCIQVAEAEV 2009
Cdd:COG4717   87 EEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyqeleALEAELAELPERLEELEER-LEELRELEEEL 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2010 KEKTELLQTLSSDVSELLKDKTHLQEK-LQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARL-SESDYEKL 2087
Cdd:COG4717  166 EELEAELAELQEELEELLEQLSLATEEeLQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELeAAALEERL 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2088 N------VSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQL-HIAEKLKERERENDSLKDKVENLE 2160
Cdd:COG4717  246 KearlllLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLgKEAEELQALPALEELEEEELEELL 325

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2161 RELQMSEENQELVILDAENSKAEVETLKTQIEEMARslkvfELDLVTLRSEKENLTKQIQEKQgqlseldklLSSFKSLL 2240
Cdd:COG4717  326 AALGLPPDLSPEELLELLDRIEELQELLREAEELEE-----ELQLEELEQEIAALLAEAGVED---------EEELRAAL 391

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2241 EEKEQAEiQIKEESKTAVEMLQNQLKELNEAVAALcgDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEAdEKKQLCV 2320
Cdd:COG4717  392 EQAEEYQ-ELKEELEELEEQLEELLGELEELLEAL--DEEELEEELEELEEELEELEEELEELREELAELEA-ELEQLEE 467

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*.
gi 55770834 2321 LQQLKESEHHADLLKGRVENLERE---LEIARTNQEHAALEAENSK 2363
Cdd:COG4717  468 DGELAELLQELEELKAELRELAEEwaaLKLALELLEEAREEYREER 513
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2082-2275 3.87e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.06  E-value: 3.87e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2082 SDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2161
Cdd:COG3883   14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2162 ELQMSEENQEL--VILDAENSKA---EVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSF 2236
Cdd:COG3883   94 ALYRSGGSVSYldVLLGSESFSDfldRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 55770834 2237 KSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAAL 2275
Cdd:COG3883  174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAA 212
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 446-1090 4.06e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.58  E-value: 4.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    446 KQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEE 525
Cdd:TIGR00618  165 KKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAY 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    526 MKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREH-----HIEQLNDKLSKTEKESKALLS 600
Cdd:TIGR00618  245 LTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHikavtQIEQQAQRIHTELQSKMRSRA 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    601 ALELKKKEYEELKEEKtlfscwksENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIR 680
Cdd:TIGR00618  325 KLLMKRAAHVKQQSSI--------EEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQ 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    681 NLHNVLDSKSVE---VETQKLAYMELQQK--AEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKD----- 750
Cdd:TIGR00618  397 SLCKELDILQREqatIDTRTSAFRDLQGQlaHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEReqqlq 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    751 ------RCYQDLHAEYESLRDLLKSKDASLVTNEDH--------------QRSLLAFDQQPAMHH-SFANIIGEQGSMPS 809
Cdd:TIGR00618  477 tkeqihLQETRKKAVVLARLLELQEEPCPLCGSCIHpnparqdidnpgplTRRMQRGEQTYAQLEtSEEDVYHQLTSERK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    810 ERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEI-----EENLMKAEQMHQSFVAETSQR 884
Cdd:TIGR00618  557 QRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLaceqhALLRKLQPEQDLQDVRLHLQQ 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    885 ISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISl 964
Cdd:TIGR00618  637 CSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEE- 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    965 NKREIEELTQENGTLKeinASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYK 1044
Cdd:TIGR00618  716 YDREFNEIENASSSLG---SDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNR 792

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*.
gi 55770834   1045 AAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLA 1090
Cdd:TIGR00618  793 LREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLE 838
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2128-2853 4.54e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.27  E-value: 4.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2128 IEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQElvildaenskaEVETLKTQIEEMARSLKVFEldlvT 2207
Cdd:TIGR00606  212 LKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLK-----------EIEHNLSKIMKLDNEIKALK----S 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2208 LRSEKENLTKQIQEK-----QGQLSELDKLLSSFKSLLEEKEQAEIQI---------------KEESKTAVEMLQNQLKE 2267
Cdd:TIGR00606  277 RKKQMEKDNSELELKmekvfQGTDEQLNDLYHNHQRTVREKERELVDCqreleklnkerrllnQEKTELLVEQGRLQLQA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2268 LNEAVAALCGDQEIMKATEQSLDPPIEE----EHQLRNSIEKLRARLEADEKKQLCVLQQLKESE----HHADLLKGRVE 2339
Cdd:TIGR00606  357 DRHQEHIRARDSLIQSLATRLELDGFERgpfsERQIKNFHTLVIERQEDEAKTAAQLCADLQSKErlkqEQADEIRDEKK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2340 NLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFE 2419
Cdd:TIGR00606  437 GLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRK 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2420 NILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVL 2499
Cdd:TIGR00606  517 LRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKL 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2500 QSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQD---QEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKN 2576
Cdd:TIGR00606  597 NKELASLEQNKNHINNELESKEEQLSSYEDKLFDvcgSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDEN 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2577 aslQDTLEVLQSSYKnlenelelTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEE 2656
Cdd:TIGR00606  677 ---QSCCPVCQRVFQ--------TEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKE 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2657 IKSSKDQLKELTLENSELKKSLDCMHK--DQVEKEGKVREE-------IAEYQLRLHEAEKKHQALLLDTNK-QYEVEIQ 2726
Cdd:TIGR00606  746 IPELRNKLQKVNRDIQRLKNDIEEQETllGTIMPEEESAKVcltdvtiMERFQMELKDVERKIAQQAAKLQGsDLDRTVQ 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2727 TYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKM---DNLKYVNQLKKENERAQGKMKLLIKSCK 2803
Cdd:TIGR00606  826 QVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLqigTNLQRRQQFEEQLVELSTEVQSLIREIK 905

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 55770834   2804 QLEEEKEILQKELSQLQaaQEKQKTGTVMDTKVDELTTEIKELKETLEEK 2853
Cdd:TIGR00606  906 DAKEQDSPLETFLEKDQ--QEKEELISSKETSNKKAQDKVNDIKEKVKNI 953
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1917-2232 4.57e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 49.16  E-value: 4.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1917 EALYleaDLEVVQTEKLCLEKDNENKQKVivclEEELSVVTSERNQLRGEldtMSKKTTALDQLSEKMKEKTQELESHQS 1996
Cdd:PRK05771   23 EALH---ELGVVHIEDLKEELSNERLRKL----RSLLTKLSEALDKLRSY---LPKLNPLREEKKKVSVKSLEELIKDVE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1997 ECLHCIqvaEAEVKEKTELLQTLSSDVSELLKDKTHLqEKLQSLEKDSQALsLTKCELENQIAQLNKEKELLVK-ESESL 2075
Cdd:PRK05771   93 EELEKI---EKEIKELEEEISELENEIKELEQEIERL-EPWGNFDLDLSLL-LGFKYVSVFVGTVPEDKLEELKlESDVE 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2076 QARLSESDYEKLNVskaleAALVEKgefalRLSSTQEEVhqLRR-GIEKLRVRIEAD-----EKKQLHIAEKLKEREREN 2149
Cdd:PRK05771  168 NVEYISTDKGYVYV-----VVVVLK-----ELSDEVEEE--LKKlGFERLELEEEGTpseliREIKEELEEIEKERESLL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2150 DSLKDKVENLERELQMSEEnqelvILDAENSKAEVEtlktqiEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSEL 2229
Cdd:PRK05771  236 EELKELAKKYLEELLALYE-----YLEIELERAEAL------SKFLKTDKTFAIEGWVPEDRVKKLKELIDKATGGSAYV 304


                  ...
gi 55770834  2230 DKL 2232
Cdd:PRK05771  305 EFV 307
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2294-2856 5.62e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.96  E-value: 5.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2294 EEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAAleaENSKGEVETLKAki 2373
Cdd:pfam15921  103 KQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDML---EDSNTQIEQLRK-- 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2374 egMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEI--INSSFENILQE--------------KEQEKVQMKEKSS 2437
Cdd:pfam15921  178 --MMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFrsLGSAISKILREldteisylkgrifpVEDQLEALKSESQ 255

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2438 TAMEMLQTQLKELNERVAALHN------DQEACKAKEQ--NLSSQVECLELE----KAQLLQGLDEAKNNYIVLQSSVNG 2505
Cdd:pfam15921  256 NKIELLLQQHQDRIEQLISEHEveitglTEKASSARSQanSIQSQLEIIQEQarnqNSMYMRQLSDLESTVSQLRSELRE 335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2506 LIQEVEDGKQKLEKK--------------DEEISRLKNQIQDQ-EQLVSKLSQVEGEHQLWKEQN--------------- 2555
Cdd:pfam15921  336 AKRMYEDKIEELEKQlvlanseltearteRDQFSQESGNLDDQlQKLLADLHKREKELSLEKEQNkrlwdrdtgnsitid 415

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2556 -----LELRNLTVE-LEQKIQVLQSK-NASLQDTLEVLQSSYKNLENELELT---KMDKMSFVEKVNKMTAKETELQREM 2625
Cdd:pfam15921  416 hlrreLDDRNMEVQrLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSSLTaqlESTKEMLRKVVEELTAKKMTLESSE 495

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2626 HEMAQKTAELQEE------LSGEKNRLAGELQLLLEEI---KSSKDQLKELTLENSELKksLDCMHKDQVEKegKVREEI 2696
Cdd:pfam15921  496 RTVSDLTASLQEKeraieaTNAEITKLRSRVDLKLQELqhlKNEGDHLRNVQTECEALK--LQMAEKDKVIE--ILRQQI 571

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2697 aEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTskeeclssqklEIDLLKSSKEELNNSLKATTQILEeLKKTKMD 2776
Cdd:pfam15921  572 -ENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ-----------EFKILKDKKDAKIRELEARVSDLE-LEKVKLV 638

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2777 N-----LKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELS---------------QLQAAQEK----------- 2825
Cdd:pfam15921  639 NagserLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRnkseemetttnklkmQLKSAQSEleqtrntlksm 718

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 55770834   2826 --------------QKTGTVMDTKVDELTTEIKELKETLEEKTKE 2856
Cdd:pfam15921  719 egsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEAMTNANKE 763
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 2358-2705 6.09e-05

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 48.70  E-value: 6.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2358 EAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKeqekvqmKEKSS 2437
Cdd:pfam06160   73 EELNDKYRFKKAKKALDEIEELLDDIEEDIKQILEELDELLESEEKNREEVEELKDKYRELRKTLLAN-------RFSYG 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2438 TAMEMLQTQLKELNERVAA---LHNDQEACKAKEQNLSSQVECLELEKAqllqgLDEAKNNYIVLQSSVNGLIQEVEDGK 2514
Cdd:pfam06160  146 PAIDELEKQLAEIEEEFSQfeeLTESGDYLEAREVLEKLEEETDALEEL-----MEDIPPLYEELKTELPDQLEELKEGY 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2515 QKLEKK---------DEEISRLKNQIQDQEQLVSKLsqvegehqlwkeqNLElrnltvELEQKIQVLQSKNASLQDTLEV 2585
Cdd:pfam06160  221 REMEEEgyalehlnvDKEIQQLEEQLEENLALLENL-------------ELD------EAEEALEEIEERIDQLYDLLEK 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2586 LQSSYKNLENELELTKmDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSK---- 2661
Cdd:pfam06160  282 EVDAKKYVEKNLPEIE-DYLEHAEEQNKELKEELERVQQSYTLNENELERVRGLEKQLEELEKRYDEIVERLEEKEvays 360

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 55770834   2662 ----------DQLKELTLENSELKKSLDCMHKDqvekEGKVREEIAEYQLRLHE 2705
Cdd:pfam06160  361 elqeeleeilEQLEEIEEEQEEFKESLQSLRKD----ELEAREKLDEFKLELRE 410
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 2067-2479 6.64e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 48.35  E-value: 6.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2067 LLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEklrvrieadekkqlhiaEKLKERE 2146
Cdd:pfam07888   24 LVVPRAELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELE-----------------SRVAELK 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2147 RENDSLKDKVENLerelqmsEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTlrsekenLTKQIQEKQGQL 2226
Cdd:pfam07888   87 EELRQSREKHEEL-------EEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKT-------LTQRVLERETEL 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2227 SELDkllssfksllEEKEQAEIQIKEEsKTAVEMLQNQLKELNEAVAALCGDQEIMKAteqSLDPPIEEEHQLRNSIEKL 2306
Cdd:pfam07888  153 ERMK----------ERAKKAGAQRKEE-EAERKQLQAKLQQTEEELRSLSKEFQELRN---SLAQRDTQVLQLQDTITTL 218

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2307 RARLEADEKKQL---CVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGl 2383
Cdd:pfam07888  219 TQKLTTAHRKEAeneALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALRE- 297

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2384 elDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMK-----EKSSTAMEMLQTQlKELNERVAALH 2458
Cdd:pfam07888  298 --GRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEvelgrEKDCNRVQLSESR-RELQELKASLR 374

                          410       420
                   ....*....|....*....|.
gi 55770834   2459 NDQeacKAKEQNLSSQVECLE 2479
Cdd:pfam07888  375 VAQ---KEKEQLQAEKQELLE 392
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 1893-2018 8.08e-05

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 44.98  E-value: 8.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1893 WKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSK 1972
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 55770834   1973 KTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQT 2018
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKT 126
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1795-2100 8.21e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 48.39  E-value: 8.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1795 RKVE--SLLNEMKELDSKLH-LQEVQlmtkIEAC---IELEKIvGELKKENSDLSEKLEyfscdhqeLLQRVETSEGLNS 1868
Cdd:PRK05771    7 KKVLivTLKSYKDEVLEALHeLGVVH----IEDLkeeLSNERL-RKLRSLLTKLSEALD--------KLRSYLPKLNPLR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1869 DLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEAL------YLEADLEVVQTEKLC------LE 1936
Cdd:PRK05771   74 EEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIErlepwgNFDLDLSLLLGFKYVsvfvgtVP 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1937 KDNENKQKVIVclEEELSVVTSERNQlrgeldtmsKKTTALDQLSEKMKEKTQELESHqseclhciQVAEAEVKEK---T 2013
Cdd:PRK05771  154 EDKLEELKLES--DVENVEYISTDKG---------YVYVVVVVLKELSDEVEEELKKL--------GFERLELEEEgtpS 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2014 ELLQTLSSDVSELLKDKTHLQEKLQSL-EKDSQALSLTKCELENQIAQLNKEKELLvkESE---SLQARLSESDYEKLnv 2089
Cdd:PRK05771  215 ELIREIKEELEEIEKERESLLEELKELaKKYLEELLALYEYLEIELERAEALSKFL--KTDktfAIEGWVPEDRVKKL-- 290

                         330
                  ....*....|.
gi 55770834  2090 SKALEAALVEK 2100
Cdd:PRK05771  291 KELIDKATGGS 301
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 18-371 8.29e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 8.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKESQV 97
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     98 NFQEGQLNSGKKQIEKLEQELKRCKSELERSQQaaqsadvslnpcntpqkifttpltpsqyysgsKYEDLKEKYNKEVEE 177
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEA--------------------------------QIEQLKEELKALREA 804

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    178 RKRLEAEVKALQAKKASQTLPQAtMNHRDIARHQASSSVFSWQQEKTPSHLSSNsqrtpirrdfSASYFSGEQEVTPSRS 257
Cdd:TIGR02168  805 LDELRAELTLLNEEAANLRERLE-SLERRIAATERRLEDLEEQIEELSEDIESL----------AAEIEELEELIEELES 873

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    258 TLQigkrdanSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIE-KEKVL 336
Cdd:TIGR02168  874 ELE-------ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNlQERLS 946

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 55770834    337 NKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDL 371
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 2214-2650 8.65e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.41  E-value: 8.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2214 NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEML---QNQLKeLNEAVAALCGDQEIM--KATEQS 2288
Cdd:COG3096  289 ELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLnlvQTALR-QQEKIERYQEDLEELteRLEEQE 367

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2289 LDPPIEEEHQLRNSIEKLRARLEADE-KKQLCVLQQ-LKESEHHADLLKGRVENLEReleiARTNQEHAALEAENSKGEV 2366
Cdd:COG3096  368 EVVEEAAEQLAEAEARLEAAEEEVDSlKSQLADYQQaLDVQQTRAIQYQQAVQALEK----ARALCGLPDLTPENAEDYL 443

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2367 ETLKAKIEGMTQSLRGLEldvvtirsEKENLTNELQKEQERISELeiinssFENILQEKEQEkvqmkEKSSTAMEMLQT- 2445
Cdd:COG3096  444 AAFRAKEQQATEEVLELE--------QKLSVADAARRQFEKAYEL------VCKIAGEVERS-----QAWQTARELLRRy 504

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2446 -QLKELNERVAALhndQEACKAKEQNLSSQVECLELEKaQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEI 2524
Cdd:COG3096  505 rSQQALAQRLQQL---RAQLAELEQRLRQQQNAERLLE-EFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR 580

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2525 SRLKNQIQDQEQLVSKLSQVEGEhqlWkeqnlelrnltVELEQKIQVLQSK-NASLQDTLEVLQSSYKNLENELELTkmd 2603
Cdd:COG3096  581 SELRQQLEQLRARIKELAARAPA---W-----------LAAQDALERLREQsGEALADSQEVTAAMQQLLEREREAT--- 643

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 55770834 2604 kmsfVEKvNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGEL 2650
Cdd:COG3096  644 ----VER-DELAARKQALESQIERLSQPGGAEDPRLLALAERLGGVL 685
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2013-2246 1.08e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2013 TELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKA 2092
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2093 LEAalvEKGEFALRLSstqeeVHQLRRGIEKLRVRIEADEKKQL--------HIAEKLKERERENDSLKDKVENLERELQ 2164
Cdd:COG4942   99 LEA---QKEELAELLR-----ALYRLGRQPPLALLLSPEDFLDAvrrlqylkYLAPARREQAEELRADLAELAALRAELE 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2165 MSEENQELVILDAENSKAEVETLKTQIEEMarslkvfeldLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKE 2244
Cdd:COG4942  171 AERAELEALLAELEEERAALEALKAERQKL----------LARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                 ..
gi 55770834 2245 QA 2246
Cdd:COG4942  241 ER 242
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1765-2094 1.12e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1765 NQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSE 1844
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1845 KLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREdigdnvakvNDSWKERFLDVENELSRIRSEKASiehealyLEAD 1924
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE---------LKALREALDELRAELTLLNEEAAN-------LRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1925 LEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQV 2004
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2005 AEAEVKEKTELLQ-------TLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTK--------CELENQIAQLNKEKELL- 2068
Cdd:TIGR02168  906 LESKRSELRRELEelreklaQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALenkieddeEEARRRLKRLENKIKELg 985

                          330       340       350
                   ....*....|....*....|....*....|..
gi 55770834   2069 ------VKESESLQARLSESDYEKLNVSKALE 2094
Cdd:TIGR02168  986 pvnlaaIEEYEELKERYDFLTAQKEDLTEAKE 1017
PRK01156 PRK01156
chromosome segregation protein; Provisional
 863-1351 1.23e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.97  E-value: 1.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   863 IEENLMKAEQMHQSFVAETSQrISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLK 942
Cdd:PRK01156  164 LERNYDKLKDVIDMLRAEISN-IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALN 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   943 ELQLLSET---LSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQyk 1019
Cdd:PRK01156  243 ELSSLEDMknrYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAE-- 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1020 qeklilLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKN------ELEQLKEAFAKEHQEFLTKLAFAE 1093
Cdd:PRK01156  321 ------INKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDynsylkSIESLKKKIEEYSKNIERMSAFIS 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1094 ERNQNLMLELETVqQALRSEMTDNQNNSKSEAGGLKQEIMTLKeeQNKMQKEVNDLLQENEQLMKVMKTkhecqNLESEP 1173
Cdd:PRK01156  395 EILKIQEIDPDAI-KKELNEINVKLQDISSKVSSLNQRIRALR--ENLDELSRNMEMLNGQSVCPVCGT-----TLGEEK 466

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1174 IRNSVKERESERNQCNFK-PQMDLEVKEIslDSYNAQLVQLEAMLRNKELKLQESEKEK-ECLQHELQTIRGDLET-SNL 1250
Cdd:PRK01156  467 SNHIINHYNEKKSRLEEKiREIEIEVKDI--DEKIVDLKKRKEYLESEEINKSINEYNKiESARADLEDIKIKINElKDK 544

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1251 QDMQSQEISGLKDCEI-DAEEKYISGPHELSTSQNdnahlqCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECI 1329
Cdd:PRK01156  545 HDKYEEIKNRYKSLKLeDLDSKRTSWLNALAVISL------IDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYID 618

                         490       500
                  ....*....|....*....|..
gi 55770834  1330 TATRKMAEEVGKLLNEVKILND 1351
Cdd:PRK01156  619 KSIREIENEANNLNNKYNEIQE 640
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 284-1020 1.40e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.66  E-value: 1.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    284 KAQNQELRNKINELELRLQGhekemkgqvnkfqeLQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTaleQK 363
Cdd:TIGR00618  186 FAKKKSLHGKAELLTLRSQL--------------LTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLT---QK 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    364 LKKLTEDLSCQRQNAESARcsleQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLT 443
Cdd:TIGR00618  249 REAQEEQLKKQQLLKQLRA----RIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRA 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    444 SVKQQLENNLEEfKQKLCRAEQAFQASQIKENELRRSMEEMKkennLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFA 523
Cdd:TIGR00618  325 KLLMKRAAHVKQ-QSSIEEQRRLLQTLHSQEIHIRDAHEVAT----SIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLC 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    524 EEMkakntsqeTMLRDLQEKINQQENSLTLEKLKLAVAdlEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALE 603
Cdd:TIGR00618  400 KEL--------DILQREQATIDTRTSAFRDLQGQLAHA--KKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    604 LKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLkTQQIKSHEYNERVRTLEMDRENLSVEIRNLH 683
Cdd:TIGR00618  470 EREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPAR-QDIDNPGPLTRRMQRGEQTYAQLETSEEDVY 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    684 NVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMclktSQLTGQVEDLEHKLQLLSNEimdKDRCYQDLHAEYESL 763
Cdd:TIGR00618  549 HQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDI----PNLQNITVRLQDLTEKLSEA---EDMLACEQHALLRKL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    764 RDLLKSKDASLVTNEDHQRSLLAfdqqpamhhsFANIIGEQGSMPSERSEcrleadqspknSAILQNRVDSLEfSLESQK 843
Cdd:TIGR00618  622 QPEQDLQDVRLHLQQCSQELALK----------LTALHALQLTLTQERVR-----------EHALSIRVLPKE-LLASRQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    844 QMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSfVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETE 923
Cdd:TIGR00618  680 LALQKMQSEKEQLTYWKEMLAQCQTLLRELETH-IEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKA 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    924 QAEIQELKKSNHL-LEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEngtLKEINASLNQEKMNLIQKSESFAN 1002
Cdd:TIGR00618  759 RTEAHFNNNEEVTaALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE---IPSDEDILNLQCETLVQEEEQFLS 835

                          730
                   ....*....|....*...
gi 55770834   1003 YIDEREKSISELSDQYKQ 1020
Cdd:TIGR00618  836 RLEEKSATLGEITHQLLK 853
PLN02939 PLN02939
transferase, transferring glycosyl groups
 2144-2476 1.45e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 47.59  E-value: 1.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2144 ERERENDSLKDkvenlERELQMSEENQElvildaenSKAEVETLKTQIEEMARSL------KVFEL-DLVTLRSEKENLT 2216
Cdd:PLN02939  103 QRDEAIAAIDN-----EQQTNSKDGEQL--------SDFQLEDLVGMIQNAEKNIlllnqaRLQALeDLEKILTEKEALQ 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2217 KQIQEKQGQLSELDkllssfkslleekeqAEIQIKEESKTAVEMLQNQLKEL-NEAVAALCGDQEIMKATEQSLDPPIEE 2295
Cdd:PLN02939  170 GKINILEMRLSETD---------------ARIKLAAQEKIHVEILEEQLEKLrNELLIRGATEGLCVHSLSKELDVLKEE 234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2296 EHQLRNSIEKLRARLE--ADEKKQLCVLqqlkESEHhaDLLKGRVENLERELEIARTNQehaaleAENSKGEVETLKAKI 2373
Cdd:PLN02939  235 NMLLKDDIQFLKAELIevAETEERVFKL----EKER--SLLDASLRELESKFIVAQEDV------SKLSPLQYDCWWEKV 302

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2374 EGMtqslrGLELDVVTIRSEKENLTneLQKEQERISELEIINSSFEnilqekeqeKVQMKEKSSTAMEMLQTQLKELNER 2453
Cdd:PLN02939  303 ENL-----QDLLDRATNQVEKAALV--LDQNQDLRDKVDKLEASLK---------EANVSKFSSYKVELLQQKLKLLEER 366

                         330       340       350
                  ....*....|....*....|....*....|.
gi 55770834  2454 VAALHND--------QEACKAKEQNLSSQVE 2476
Cdd:PLN02939  367 LQASDHEihsyiqlyQESIKEFQDTLSKLKE 397
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1926-2857 1.48e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.86  E-value: 1.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1926 EVVQTEKLCLEKDNENKQKVivclEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVA 2005
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKA----ESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHEL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2006 EAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCE--------------LENQIAQLNKEKELLVKE 2071
Cdd:pfam01576   81 ESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTteakikkleedillLEDQNSKLSKERKLLEER 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2072 SESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQeevhQLRRGIEKLRVRIEADekkqlhiAEKLKEREREnds 2151
Cdd:pfam01576  161 ISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEE----KGRQELEKAKRKLEGE-------STDLQEQIAE--- 226

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2152 LKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDK 2231
Cdd:pfam01576  227 LQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKT 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2232 LLSSfkSLLEEKEQAEIQIKEEskTAVEMLQNQLKELNEAVAALCGDQEIMKATE-QSLDPPIEEEHQLRNSIEKLRARL 2310
Cdd:pfam01576  307 ELED--TLDTTAAQQELRSKRE--QEVTELKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQAKRNKANLEKAKQAL 382

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2311 EADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENskgEVETLKAKIEGMTQSLRGLELDVVTI 2390
Cdd:pfam01576  383 ESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAE---KLSKLQSELESVSSLLNEAEGKNIKL 459

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2391 RSEKENLTNELQKEQE--------------RISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAA 2456
Cdd:pfam01576  460 SKDVSSLESQLQDTQEllqeetrqklnlstRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGT 539

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2457 LHNDQEACKAKEQNLSSQVECLElEKAQLLQGLDEAKNNyivLQSSVNGLIQEVEDGKQ---KLEKKDEEISR-LKNQIQ 2532
Cdd:pfam01576  540 LEALEEGKKRLQRELEALTQQLE-EKAAAYDKLEKTKNR---LQQELDDLLVDLDHQRQlvsNLEKKQKKFDQmLAEEKA 615

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2533 DQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVN 2612
Cdd:pfam01576  616 ISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVE 695

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2613 KMTAKETELQREMHEM---------------AQKTAELQ--EELSGEKNRL----AGELQLLLEEIKSSKDQL----KEL 2667
Cdd:pfam01576  696 EMKTQLEELEDELQATedaklrlevnmqalkAQFERDLQarDEQGEEKRRQlvkqVRELEAELEDERKQRAQAvaakKKL 775

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2668 TLENSELKKSLDCMHK---DQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTN------KQYEVEIQTYREKLTSKEEC 2738
Cdd:pfam01576  776 ELDLKELEAQIDAANKgreEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKesekklKNLEAELLQLQEDLAASERA 855

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2739 LSSQKLEIDLLkssKEELNNSLKATTQILEELKKTKmdnlKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQ 2818
Cdd:pfam01576  856 RRQAQQERDEL---ADEIASGASGKSALQDEKRRLE----ARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAA 928

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|
gi 55770834   2819 LQAAQEKQKTG-TVMDTKVDELTTEIKELKETLEEKTKEA 2857
Cdd:pfam01576  929 ERSTSQKSESArQQLERQNKELKAKLQEMEGTVKSKFKSS 968
PLN02939 PLN02939
transferase, transferring glycosyl groups
 2002-2309 1.51e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 47.59  E-value: 1.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSE 2081
Cdd:PLN02939  102 MQRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSE 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2082 SDyEKLNVSkALEAALVEKGEfalrlsstqeevHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2161
Cdd:PLN02939  182 TD-ARIKLA-AQEKIHVEILE------------EQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKA 247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2162 EL-QMSEENQELVILDAENS--KAEVETLKTQ-IEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFK 2237
Cdd:PLN02939  248 ELiEVAETEERVFKLEKERSllDASLRELESKfIVAQEDVSKLSPLQYDCWWEKVENLQDLLDRATNQVEKAALVLDQNQ 327

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834  2238 SLLEEKEQAEIQIKE-----ESKTAVEMLQNQLKELNEAVAAlcGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRAR 2309
Cdd:PLN02939  328 DLRDKVDKLEASLKEanvskFSSYKVELLQQKLKLLEERLQA--SDHEIHSYIQLYQESIKEFQDTLSKLKEESKKR 402
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2509-2894 1.55e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 47.73  E-value: 1.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2509 EVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQK-IQVLQSKNASLQDTLEVLQ 2587
Cdd:TIGR00606  232 QLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKmEKVFQGTDEQLNDLYHNHQ 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2588 SSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELsgeknrLAGELQLLLEEIKSSKDQLKEL 2667
Cdd:TIGR00606  312 RTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHI------RARDSLIQSLATRLELDGFERG 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2668 TLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQAlLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEID 2747
Cdd:TIGR00606  386 PFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADE-IRDEKKGLGRTIELKKEILEKKQEELKFVIKELQ 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2748 LLKSSKEELNNSLKATTQILEELKKTKMDNLkyVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQK 2827
Cdd:TIGR00606  465 QLEGSSDRILELDQELRKAERELSKAEKNSL--TETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTK 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2828 TGTVMDTKV--------DELTTEI------KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQS 2893
Cdd:TIGR00606  543 DKMDKDEQIrkiksrhsDELTSLLgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLS 622


                   .
gi 55770834   2894 K 2894
Cdd:TIGR00606  623 S 623
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 828-1352 1.94e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.42  E-value: 1.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSA-L 906
Cdd:pfam15921  147 LQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKiL 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    907 ENKEKELQLLNDKVETEQAEIQELKKsnhlleDSLKELQLLsetLSLEKKEMSSIISLNKREIEELTQENGTLKEINASL 986
Cdd:pfam15921  227 RELDTEISYLKGRIFPVEDQLEALKS------ESQNKIELL---LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSI 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    987 nQEKMNLIQKSESFANYIDEREksISELSDQYKQekliLLQRCEETGNAYED-LSQKYKAAQEKNSKLECLLNECTSLCE 1065
Cdd:pfam15921  298 -QSQLEIIQEQARNQNSMYMRQ--LSDLESTVSQ----LRSELREAKRMYEDkIEELEKQLVLANSELTEARTERDQFSQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1066 NRKNELEQLKEAFAKEHQEfLTKLAFAEERNQNLMlELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEE-QNKMQK 1144
Cdd:pfam15921  371 ESGNLDDQLQKLLADLHKR-EKELSLEKEQNKRLW-DRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMER 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1145 EVNDLLQENEQLMKVMKTKHECQNLEsEPIRNSVKE--------RESERNQCNFKPQmdLEVKEISLDSYNAQLVQLEAM 1216
Cdd:pfam15921  449 QMAAIQGKNESLEKVSSLTAQLESTK-EMLRKVVEEltakkmtlESSERTVSDLTAS--LQEKERAIEATNAEITKLRSR 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1217 LRNKELKLQESEKEKECLQH---ELQTIRGDL-ETSNLQDMQSQEISGLKdcEIDAEEKYISGPHELSTSQ-----NDN- 1286
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNvqtECEALKLQMaEKDKVIEILRQQIENMT--QLVGQHGRTAGAMQVEKAQlekeiNDRr 603

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 55770834   1287 ---AHLQCSLQTTMNKLNELEKICEILQAEKYELVtelnDSRSECITATRKMAEEVGKLLNEVKILNDD 1352
Cdd:pfam15921  604 lelQEFKILKDKKDAKIRELEARVSDLELEKVKLV----NAGSERLRAVKDIKQERDQLLNEVKTSRNE 668
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2634-2883 2.00e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.23  E-value: 2.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2634 ELQEELSGEKNRLAGELqllLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEyqlrlhEAEKkhqal 2713
Cdd:PRK05771   35 DLKEELSNERLRKLRSL---LTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELE------KIEK----- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2714 lldtnkqyEV-EIQTYREKLTSKEECLSSQKLEIDLLK--SSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENER 2790
Cdd:PRK05771  101 --------EIkELEEEISELENEIKELEQEIERLEPWGnfDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYI 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2791 AQGKMK---LLIKSCKQLEEEKEILQK-ELSQLQAAQEkqktGTVMD------TKVDELTTEIKELKETLEEKTKE-ADE 2859
Cdd:PRK05771  173 STDKGYvyvVVVVLKELSDEVEEELKKlGFERLELEEE----GTPSElireikEELEEIEKERESLLEELKELAKKyLEE 248

                         250       260
                  ....*....|....*....|....
gi 55770834  2860 YLDKYCSLLISHEKLEKAKEMLET 2883
Cdd:PRK05771  249 LLALYEYLEIELERAEALSKFLKT 272
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 896-1232 2.06e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 2.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    896 QNVVAETLSALENKEKELQL---------LNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSsiislnk 966
Cdd:TIGR02168  208 QAEKAERYKELKAELRELELallvlrleeLREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELE------- 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    967 REIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELsdqyKQEKLILLQRCEETGNAYEDLSQKYKAA 1046
Cdd:TIGR02168  281 EEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEEL----ESKLDELAEELAELEEKLEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1047 QEKNSKLECLLNECTSLCENRKNELEQLKEAFAkehqefltklafaeernqnlmleletvqqALRSEMTDNQNnskseag 1126
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVA-----------------------------QLELQIASLNN------- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1127 glkqEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKT----KHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEIS 1202
Cdd:TIGR02168  401 ----EIERLEARLERLEDRRERLQQEIEELLKKLEEaelkELQAELEELEEELEELQEELERLEEALEELREELEEAEQA 476

                          330       340       350
                   ....*....|....*....|....*....|
gi 55770834   1203 LDSYNAQLVQLEAMLRNKELKLQESEKEKE 1232
Cdd:TIGR02168  477 LDAAERELAQLQARLDSLERLQENLEGFSE 506
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2583-2852 2.23e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.98  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2583 LEVLQSSYKNLENELELTKMdKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLL---LEEIKS 2659
Cdd:PRK03918  157 LDDYENAYKNLGEVIKEIKR-RIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLekeVKELEE 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2660 SKDQLKELTLENSELKKSLdcmhKDQVEKEGKVREEIAEYQLRLHEAEKKHQAL------------LLDTNKQYEVEIQT 2727
Cdd:PRK03918  236 LKEEIEELEKELESLEGSK----RKLEEKIRELEERIEELKKEIEELEEKVKELkelkekaeeyikLSEFYEEYLDELRE 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2728 YREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEE 2807
Cdd:PRK03918  312 IEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEK 391

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 55770834  2808 EKEILQKELSQLQAAQEKqktgtvMDTKVDELTTEIKELKETLEE 2852
Cdd:PRK03918  392 ELEELEKAKEEIEEEISK------ITARIGELKKEIKELKKAIEE 430
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2467-2677 2.29e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.36  E-value: 2.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2467 KEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKL---SQ 2543
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaraLY 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2544 VEGEHQLWKEQNLELRNLTvELEQKIQVLQSKNASLQDTLEVLQSSYKNLENEleltkmdKMSFVEKVNKMTAKETELQR 2623
Cdd:COG3883   97 RSGGSVSYLDVLLGSESFS-DFLDRLSALSKIADADADLLEELKADKAELEAK-------KAELEAKLAELEALKAELEA 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 55770834 2624 EMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKS 2677
Cdd:COG3883  169 AKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2654-2900 2.31e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2654 LEEIKSSKDQLKELTLENSELKksldcmhkDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLT 2733
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKR--------QQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2734 SKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKY-VNQLKKENERAQGKMKLLIKSCKQLEEEKEIL 2812
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEkIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2813 QKELSQLQAAQEKQKTG-TVMDTKVDELTTEIKELKET-------LEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQ 2884
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREiEEERKRRDKLTEEYAELKEEledlraeLEEVDKEFAETRDELKDYREKLEKLKREINELKRE 407

                          250
                   ....*....|....*.
gi 55770834   2885 VAHLCSQQSKQDSRGS 2900
Cdd:TIGR02169  408 LDRLQEELQRLSEELA 423
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 2419-2674 2.47e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.97  E-value: 2.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2419 ENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQ--NLSSQVecleleKAQLLQGLDEAKNny 2496
Cdd:PRK10929   26 KQITQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQQVIDNfpKLSAEL------RQQLNNERDEPRS-- 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2497 IVLQSSVNGLIQEV-EDGKQKLEKkdeeiSRLKNQIQDQEQLVS-KLSQVegehqlwKEQNLELRNLTVELEQKIQVLQS 2574
Cdd:PRK10929   98 VPPNMSTDALEQEIlQVSSQLLEK-----SRQAQQEQDRAREISdSLSQL-------PQQQTEARRQLNEIERRLQTLGT 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2575 KNASL-QDTLEVLQ---SSYKNLENELELTKMDkmsfvekvnkmTAKETELQREMHEMAQKTAElqeelsgeknRLAGEL 2650
Cdd:PRK10929  166 PNTPLaQAQLTALQaesAALKALVDELELAQLS-----------ANNRQELARLRSELAKKRSQ----------QLDAYL 224

                         250       260
                  ....*....|....*....|....
gi 55770834  2651 QLLLEEIKSSKDQLKELTLENSEL 2674
Cdd:PRK10929  225 QALRNQLNSQRQREAERALESTEL 248
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 844-1156 2.49e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 2.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    844 QMNSDLQKQCEELVQIKGEIEENlmkaeqmhQSFVAETSQRISKLQEDT------------------SAHQNVVAETLSA 905
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERL--------DLIIDEKRQQLERLRRERekaeryqallkekreyegYELLKEKEALERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    906 LENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLE-----KKEMSSI---ISLNKREIEELTQENG 977
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrvKEKIGELeaeIASLERSIAEKERELE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    978 TLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQY---KQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLE 1054
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYaelKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1055 CLLNECTSLCENRKNELEQLKEAFAKEHQEfltkLAFAEERNQNLMLELETVQQALRsEMTDNQNNSKSEAGGLKQEIMT 1134
Cdd:TIGR02169  399 REINELKRELDRLQEELQRLSEELADLNAA----IAGIEAKINELEEEKEDKALEIK-KQEWKLEQLAADLSKYEQELYD 473

                          330       340
                   ....*....|....*....|..
gi 55770834   1135 LKEEQNKMQKEVNDLLQENEQL 1156
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRELAEA 495
PLN02939 PLN02939
transferase, transferring glycosyl groups
 2342-2679 2.53e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 2.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2342 ERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQS--------LRGLElDVVTIRSEKENLTNELQKEQERISELEi 2413
Cdd:PLN02939  106 EAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEKNilllnqarLQALE-DLEKILTEKEALQGKINILEMRLSETD- 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2414 inssfenilqekEQEKVQMKEKSSTamEMLQTQLKELNERVAALHNDQEACkakEQNLSSQVECLELEKAQLlqgldeaK 2493
Cdd:PLN02939  184 ------------ARIKLAAQEKIHV--EILEEQLEKLRNELLIRGATEGLC---VHSLSKELDVLKEENMLL-------K 239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2494 NNYIVLQSSVNGlIQEVEDGKQKLEKK----DEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLE--LRNLTVELEQ 2567
Cdd:PLN02939  240 DDIQFLKAELIE-VAETEERVFKLEKErsllDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVENLQdlLDRATNQVEK 318

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2568 KIQVLQsKNASLQDTLEVLQSSYKNLE-NELELTKMDKMSfvekvNKMTAKETELQREMHEMAQktaelqeelsgeknrl 2646
Cdd:PLN02939  319 AALVLD-QNQDLRDKVDKLEASLKEANvSKFSSYKVELLQ-----QKLKLLEERLQASDHEIHS---------------- 376

                         330       340       350
                  ....*....|....*....|....*....|...
gi 55770834  2647 agELQLLLEEIKSSKDQLKELtLENSElKKSLD 2679
Cdd:PLN02939  377 --YIQLYQESIKEFQDTLSKL-KEESK-KRSLE 405
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2191-2441 2.74e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.46  E-value: 2.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2191 IEEMARslkvfeLDLVTLRSEKENLTKQIQE----------KQGQ----------LSELDKLLSSFKSLLEEkeqAEIQI 2250
Cdd:PRK05771    3 PVRMKK------VLIVTLKSYKDEVLEALHElgvvhiedlkEELSnerlrklrslLTKLSEALDKLRSYLPK---LNPLR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2251 KEESKTAVEMLQNQLKELNEAVAALcgdqeimkatEQSLDPPIEEEHQLRNSIEKLRARLEADEK-KQLCVLQQLKESEH 2329
Cdd:PRK05771   74 EEKKKVSVKSLEELIKDVEEELEKI----------EKEIKELEEEISELENEIKELEQEIERLEPwGNFDLDLSLLLGFK 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2330 HADLLKGRVeNLERELEIARTNQEHAALEAENSKGE----VETLKAKIEGMTQSLRGLELDVVTIrSEKENLTNELQKEQ 2405
Cdd:PRK05771  144 YVSVFVGTV-PEDKLEELKLESDVENVEYISTDKGYvyvvVVVLKELSDEVEEELKKLGFERLEL-EEEGTPSELIREIK 221

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 55770834  2406 ERI----SELEIINSSFENILQEKEQEKVQMKEKSSTAME 2441
Cdd:PRK05771  222 EELeeieKERESLLEELKELAKKYLEELLALYEYLEIELE 261
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 828-1122 3.38e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 3.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKaeqmhqsfvaETSQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKD----------LGEEEQLRVKEKIGELEAEIASLERSIA 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    988 QEKMNLiqksesfanyIDEREKSISELSDqykqekliLLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENR 1067
Cdd:TIGR02169  392 EKLEKL----------KREINELKRELDR--------LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ 453

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 55770834   1068 KNELEQLKEAFAKEHQEFL---TKLAFAEERNQNLMLEL---ETVQQALRSEMTDNQNNSK 1122
Cdd:TIGR02169  454 EWKLEQLAADLSKYEQELYdlkEEYDRVEKELSKLQRELaeaEAQARASEERVRGGRAVEE 514
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2025-2584 3.44e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.43  E-value: 3.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2025 ELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEaalvekgefa 2104
Cdd:PRK01156  173 DVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALN---------- 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2105 lRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEK------------LKERERENDSLKDK---------VENLEREL 2163
Cdd:PRK01156  243 -ELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELeerhmkiindpvYKNRNYINDYFKYKndienkkqiLSNIDAEI 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2164 QMSEEN-QELVILDAENS-----KAEVETLKTQIEEmarsLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFK 2237
Cdd:PRK01156  322 NKYHAIiKKLSVLQKDYNdyikkKSRYDDLNNQILE----LEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEIL 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2238 SLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSL-----------DPPIEEEHQLRNSIEKL 2306
Cdd:PRK01156  398 KIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgtTLGEEKSNHIINHYNEK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2307 RARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREleiartnqehaalEAENSKGEVETLKAKIEGMTQSLRGLEld 2386
Cdd:PRK01156  478 KSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEIN-------------KSINEYNKIESARADLEDIKIKINELK-- 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2387 vvtirsEKENLTNELqKEQERISELEIINSSFENILQekeqekvQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKA 2466
Cdd:PRK01156  543 ------DKHDKYEEI-KNRYKSLKLEDLDSKRTSWLN-------ALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEI 608

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2467 KEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEG 2546
Cdd:PRK01156  609 GFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRK 688

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 55770834  2547 EHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLE 2584
Cdd:PRK01156  689 ALDDAKANRARLESTIEILRTRINELSDRINDINETLE 726
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 435-1099 3.55e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 3.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    435 LQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKE-NELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIK 513
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEqLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    514 QCLNQSQNFAEEMKAKNTSQETMLRDLQEKInqQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLsktek 593
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKLTEEY--AELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI----- 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    594 eskallsalelkkkeyEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRE 673
Cdd:TIGR02169  402 ----------------NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    674 NLSVEIRNLHNVLD--SKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQ-LTGQVEDL-----EHKLQL---- 741
Cdd:TIGR02169  466 KYEQELYDLKEEYDrvEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgVHGTVAQLgsvgeRYATAIevaa 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    742 ---LSNEIMDKD----RCYQDLHAE---------------YESLRDLLKSK-------------------------DASL 774
Cdd:TIGR02169  546 gnrLNNVVVEDDavakEAIELLKRRkagratflplnkmrdERRDLSILSEDgvigfavdlvefdpkyepafkyvfgDTLV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    775 VTNEDHQRSLLA-----------FDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKnsaiLQNRVDSLEFSLESQK 843
Cdd:TIGR02169  626 VEDIEAARRLMGkyrmvtlegelFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEG----LKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    844 QMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFvaetSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETE 923
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL----KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    924 QAEIQELKKsnHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEngtlkeiNASLNQEKMNLIQKSESFANY 1003
Cdd:TIGR02169  778 EEALNDLEA--RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE-------KEYLEKEIQELQEQRIDLKEQ 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1004 IDEREKSISELsdqyKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNEctslCENRKNELEQLKEAFAKEHQ 1083
Cdd:TIGR02169  849 IKSIEKEIENL----NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE----LERKIEELEAQIEKKRKRLS 920

                          730
                   ....*....|....*.
gi 55770834   1084 EFLTKLAFAEERNQNL 1099
Cdd:TIGR02169  921 ELKAKLEALEEELSEI 936
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1899-2111 3.65e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.98  E-value: 3.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1899 DVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTM-------S 1971
Cdd:COG3883   20 AKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaralyrsG 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1972 KKTTALDQLsekmkektqeLESHQ-SECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLT 2050
Cdd:COG3883  100 GSVSYLDVL----------LGSESfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 55770834 2051 KCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQ 2111
Cdd:COG3883  170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 1982-2584 3.70e-04

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 46.33  E-value: 3.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1982 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKdsqalsltkcelenqiaql 2061
Cdd:PRK10246  191 EQHKSARTELEKLQAQASGVALLTPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTR------------------- 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2062 nkeKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALR-LSSTQEE----VHQLRRGIEKLRVRIEADEKKQL 2136
Cdd:PRK10246  252 ---LDELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPARQLRpHWERIQEqsaaLAHTRQQIEEVNTRLQSTMALRA 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2137 HI----AEKLKERERENDSLKDKVENLERELQMSEE--NQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:PRK10246  329 RIrhhaAKQSAELQAQQQSLNTWLAEHDRFRQWNNElaGWRAQFSQQTSDREQLRQWQQQLTHAEQKLNALPAITLTLTA 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2211 EKenlTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEesktAVEMLQNQLKELNEAVAALcgDQEIMKATEQSLD 2290
Cdd:PRK10246  409 DE---VAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQV----AIQNVTQEQTQRNAALNEM--RQRYKEKTQQLAD 479

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2291 -PPIEEEHQLRNSIEKLRARLEADEKKQLCvlqqlKESEHHAdllkgrVENLErELEIARTNQEHAALEAE--NSKGEVE 2367
Cdd:PRK10246  480 vKTICEQEARIKDLEAQRAQLQAGQPCPLC-----GSTSHPA------VEAYQ-ALEPGVNQSRLDALEKEvkKLGEEGA 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2368 TLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELqkeQERISELEIINSSFENI---LQEKEQEKVQMKEKSSTamEMLQ 2444
Cdd:PRK10246  548 ALRGQLDALTKQLQRDESEAQSLRQEEQALTQQW---QAVCASLNITLQPQDDIqpwLDAQEEHERQLRLLSQR--HELQ 622

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2445 TQLKELNERVAALhndQEACKAKEQNLSSQVECLELekaQLLQGLDEAKnnyivlqssvngLIQEVEDGKQKLEKKDEEI 2524
Cdd:PRK10246  623 GQIAAHNQQIIQY---QQQIEQRQQQLLTALAGYAL---TLPQEDEEAS------------WLATRQQEAQSWQQRQNEL 684

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 55770834  2525 SRLKNQIQDQEQLVSKLSQ----VEGEHQLWKEQNLELRNLTVELEQKIQVLQSknaslQDTLE 2584
Cdd:PRK10246  685 TALQNRIQQLTPLLETLPQsddlPHSEETVALDNWRQVHEQCLSLHSQLQTLQQ-----QDVLE 743
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 249-565 3.80e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.20  E-value: 3.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   249 EQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKgQVNKFQELQLQLE----K 324
Cdd:PRK10929  108 EQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIERRLQTLGTPNT-PLAQAQLTALQAEsaalK 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   325 AKVELIEKEKVLNKCRDELVRTTAqyDQASTKYTALEQKLKKLTEDLSCQRQ-NAESArcsleqkikekekefqeeLSRQ 403
Cdd:PRK10929  187 ALVDELELAQLSANNRQELARLRS--ELAKKRSQQLDAYLQALRNQLNSQRQrEAERA------------------LEST 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   404 QRsfqtLDQECIQMKARLTQELQQAKNMHNVL--QA-ELDKLTSVKQQLENNLEEFKQKLCR-AEQA--FQASQIKENEL 477
Cdd:PRK10929  247 EL----LAEQSGDLPKSIVAQFKINRELSQALnqQAqRMDLIASQQRQAASQTLQVRQALNTlREQSqwLGVSNALGEAL 322

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   478 RRSME---EMKKennllkshSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKN---TSQETMLRDLQEKInQQE--N 549
Cdd:PRK10929  323 RAQVArlpEMPK--------PQQLDTEMAQLRVQRLRYEDLLNKQPQLRQIRQADGqplTAEQNRILDAQLRT-QREllN 393

                         330       340
                  ....*....|....*....|....*
gi 55770834   550 S---------LTLEKLKLAVADLEK 565
Cdd:PRK10929  394 SllsggdtliLELTKLKVANSQLED 418
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2691-2886 3.80e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.80e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2691 KVREEIAEYQLRLHEAEKKHQALLLDTNKQyEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEEL 2770
Cdd:COG4942   31 QLQQEIAELEKELAALKKEEKALLKQLAAL-ERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2771 KKT---------------------KMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTg 2829
Cdd:COG4942  110 LRAlyrlgrqpplalllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA- 188

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834 2830 tvmdtkvdELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVA 2886
Cdd:COG4942  189 --------ALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 420-999 3.99e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.17  E-value: 3.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKa 499
Cdd:TIGR04523  107 KINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNI- 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    500 revchlEAELKNIKQCLNQSQNFAEEMKA---KNTSQETMLRDLQEKINQQENSLTLEKLKLA--VADLEKQRDCSQDLL 574
Cdd:TIGR04523  186 ------QKNIDKIKNKLLKLELLLSNLKKkiqKNKSLESQISELKKQNNQLKDNIEKKQQEINekTTEISNTQTQLNQLK 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    575 KKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKtlfscwKSENEKLLTQMESEKENLQSKINHLETCLKTQ 654
Cdd:TIGR04523  260 DEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN------NQKEQDWNKELKSELKNQEKKLEEIQNQISQN 333

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    655 QIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLaymelqqkaefSDQKHQKEIENMCLKTSQLTGQVED 734
Cdd:TIGR04523  334 NKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK-----------ENQSYKQEIKNLESQINDLESKIQN 402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    735 LEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASL--VTNEDHQRSLlafdqqpamhhSFANIIGEQGSMPSERS 812
Cdd:TIGR04523  403 QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIkdLTNQDSVKEL-----------IIKNLDNTRESLETQLK 471

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    813 ECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDt 892
Cdd:TIGR04523  472 VLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD- 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    893 sahqnvvaetlsaleNKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEEL 972
Cdd:TIGR04523  551 ---------------DFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSL 615

                          570       580
                   ....*....|....*....|....*..
gi 55770834    973 TQENGTLKEINASLNQEKMNLIQKSES 999
Cdd:TIGR04523  616 EKELEKAKKENEKLSSIIKNIKSKKNK 642
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 627-1156 4.94e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 4.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    627 EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRN---LHNVLDSKSVEVETQKLAYMEL 703
Cdd:TIGR04523   60 DKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNdkeQKNKLEVELNKLEKQKKENKKN 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    704 QQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRS 783
Cdd:TIGR04523  140 IDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQ 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    784 LLAFDQQ----------------------PAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLES 841
Cdd:TIGR04523  220 ISELKKQnnqlkdniekkqqeinektteiSNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISD 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    842 ---------QKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSfVAETSQRISKLQEDTSAHQNVVAETLSALENKEKE 912
Cdd:TIGR04523  300 lnnqkeqdwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQ-ISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE 378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    913 -------LQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINAS 985
Cdd:TIGR04523  379 nqsykqeIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKN 458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    986 LNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETgnayEDLSQKYKAAQEKNSKLECLLNECTSLCE 1065
Cdd:TIGR04523  459 LDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEKLESEKK 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1066 NRKNELEQLKEAFAKEHQEfLTKLAFAEE--RNQNLMLELETVQQALRSEMTDNQN---NSKSEAGGLKQEIMTLKEEQN 1140
Cdd:TIGR04523  535 EKESKISDLEDELNKDDFE-LKKENLEKEidEKNKEIEELKQTQKSLKKKQEEKQElidQKEKEKKDLIKEIEEKEKKIS 613

                          570
                   ....*....|....*.
gi 55770834   1141 KMQKEVNDLLQENEQL 1156
Cdd:TIGR04523  614 SLEKELEKAKKENEKL 629
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2036-2198 5.08e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.53  E-value: 5.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2036 KLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEA--ALVEKGEFALRLSSTQEE 2113
Cdd:COG1579   11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEveARIKKYEEQLGNVRNNKE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2114 VHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELqmsEENQELVILDAENSKAEVETLKTQIEE 2193
Cdd:COG1579   91 YEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAEL---EEKKAELDEELAELEAELEELEAEREE 167


                 ....*
gi 55770834 2194 MARSL 2198
Cdd:COG1579  168 LAAKI 172
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2473-2709 5.17e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 5.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2473 SQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQlvsklsqvegehqlwk 2552
Cdd:COG3883   16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEA---------------- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2553 eqnlELRNLTVELEQKIQVLQsKNASLQDTLEVLQSSyKNLENELeltkmDKMSFVEKVNKMTAKE-TELQREMHEMAQK 2631
Cdd:COG3883   80 ----EIEERREELGERARALY-RSGGSVSYLDVLLGS-ESFSDFL-----DRLSALSKIADADADLlEELKADKAELEAK 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 55770834 2632 TAELQEELSgeknrlagELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKK 2709
Cdd:COG3883  149 KAELEAKLA--------ELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAA 218
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2312-2855 5.57e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 45.66  E-value: 5.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2312 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELeiarTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIR 2391
Cdd:PRK01156  149 AQRKKILDEILEINSLERNYDKLKDVIDMLRAEI----SNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLS 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2392 SEKENLTNELQKEQERISELeiinSSFENILQEKEQEkVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNL 2471
Cdd:PRK01156  225 IEYNNAMDDYNNLKSALNEL----SSLEDMKNRYESE-IKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYIND 299

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2472 SSQVECLELEKAQLLQGLDEAKNNYivlqSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQlw 2551
Cdd:PRK01156  300 YFKYKNDIENKKQILSNIDAEINKY----HAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIE-- 373

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2552 kEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREM------ 2625
Cdd:PRK01156  374 -SLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMemlngq 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2626 --------HEMAQKTAELQEELSGEKNRLAgelqlllEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKE-------G 2690
Cdd:PRK01156  453 svcpvcgtTLGEEKSNHIINHYNEKKSRLE-------EKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSineynkiE 525

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2691 KVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKL-EIDLLKSSKEELNNSLKATTQILEE 2769
Cdd:PRK01156  526 SARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLiDIETNRSRSNEIKKQLNDLESRLQE 605

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2770 L----------------------------------KKTKMDNL-KYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQK 2814
Cdd:PRK01156  606 IeigfpddksyidksireieneannlnnkyneiqeNKILIEKLrGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKK 685

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*
gi 55770834  2815 ELSQLQAAQ----EKQKTGTVMDTKVDELTTEIKELKETLEEKTK 2855
Cdd:PRK01156  686 SRKALDDAKanraRLESTIEILRTRINELSDRINDINETLESMKK 730
mukB PRK04863
chromosome partition protein MukB;
2209-2580 6.72e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 6.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2209 RSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATE-- 2286
Cdd:PRK04863  278 ANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQAdl 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2287 QSLDPPIEEEHQLRNSI----EKLRARLEADEKKQLCVLQQLKESEHHADLLKGRV---ENLERELEIARTNQEHAALEA 2359
Cdd:PRK04863  358 EELEERLEEQNEVVEEAdeqqEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAiqyQQAVQALERAKQLCGLPDLTA 437

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2360 ENSKGEVETLKAKIEGMTQSLRGLE--LDVV-TIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVqmkeks 2436
Cdd:PRK04863  438 DNAEDWLEEFQAKEQEATEELLSLEqkLSVAqAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRRLREQRHL------ 511

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2437 STAMEMLQTQLKELnERVAALHND-----QEACKAKEQNLS--SQVECLELEKAQLLQGLDEAKNNYIVLQSSVngliqe 2509
Cdd:PRK04863  512 AEQLQQLRMRLSEL-EQRLRQQQRaerllAEFCKRLGKNLDdeDELEQLQEELEARLESLSESVSEARERRMAL------ 584

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2510 vedgKQKLEKKDEEISRLKNQ----IQDQEQLvSKLSQVEGEH--------QLWKEQNLELRNLTVE---LEQKIQVLQS 2574
Cdd:PRK04863  585 ----RQQLEQLQARIQRLAARapawLAAQDAL-ARLREQSGEEfedsqdvtEYMQQLLERERELTVErdeLAARKQALDE 659


                  ....*.
gi 55770834  2575 KNASLQ 2580
Cdd:PRK04863  660 EIERLS 665
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 355-1252 6.76e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.42  E-value: 6.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    355 TKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRsfQTLDQECIQMKARLTQELQQAknmhnv 434
Cdd:TIGR00606  182 TRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQ--LESSREIVKSYENELDPLKNR------ 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    435 lQAELDKLTSVKQQLENNLEEFKQ-KLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIK 513
Cdd:TIGR00606  254 -LKEIEHNLSKIMKLDNEIKALKSrKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLN 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    514 QCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEK 593
Cdd:TIGR00606  333 KERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    594 ESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRE 673
Cdd:TIGR00606  413 LCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEK 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    674 NLSVEIRNLHNV---------------LDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHK 738
Cdd:TIGR00606  493 NSLTETLKKEVKslqnekadldrklrkLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNK 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    739 LQLlsNEIMDKDRcyQDLHAEYESLRDLLKSKdASLVTNEDHQRSLLAF--DQQPAMHHSFANIIGEQgSMPSERSECRL 816
Cdd:TIGR00606  573 KQL--EDWLHSKS--KEINQTRDRLAKLNKEL-ASLEQNKNHINNELESkeEQLSSYEDKLFDVCGSQ-DEESDLERLKE 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    817 EADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEEnlmkaeqmhqsfvaetsqRISKLQEDTSAHQ 896
Cdd:TIGR00606  647 EIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQE------------------FISDLQSKLRLAP 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    897 NVVAETLSALENKEKELQLLNDKVETEQAEIQelkksnhLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEn 976
Cdd:TIGR00606  709 DKLKSTESELKKKEKRRDEMLGLAPGRQSIID-------LKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPE- 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    977 gtlkEINASLNQEKMNLIQKsesFANYIDEREKSISELSDQYKQEKLILlqrceetgnAYEDLSQKYKAAQEKNSKLECL 1056
Cdd:TIGR00606  781 ----EESAKVCLTDVTIMER---FQMELKDVERKIAQQAAKLQGSDLDR---------TVQQVNQEKQEKQHELDTVVSK 844

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1057 LNECTSLCENRKNELEQLKEAFAKEHQEFLtKLAFAEERNQNLMLELETVQQALRSemtdnqnnskseaggLKQEIMTLK 1136
Cdd:TIGR00606  845 IELNRKLIQDQQEQIQHLKSKTNELKSEKL-QIGTNLQRRQQFEEQLVELSTEVQS---------------LIREIKDAK 908

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1137 EEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQmdlevkeislDSYNAQLVQLEAM 1216
Cdd:TIGR00606  909 EQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQ----------DGKDDYLKQKETE 978

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 55770834   1217 LRNKELKLQESEKEKECLQHELQTIRGDLETSNLQD 1252
Cdd:TIGR00606  979 LNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQE 1014
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 2053-2453 6.78e-04

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 45.07  E-value: 6.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2053 ELENQIAQLNKEKELLVKESESLQARLSESD-YEKLNVSKALEAALVEKgefalRLSSTQEEVHQLRRGIEKLRVRIEAD 2131
Cdd:pfam05622   18 ELDQQVSLLQEEKNSLQQENKKLQERLDQLEsGDDSGTPGGKKYLLLQK-----QLEQLQEENFRLETARDDYRIKCEEL 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2132 EKKQLHiaekLKERERENDSLKDKVENLERELQ-MSEENQELVILDAEnskaeVETLKTQIEEMA---RSLKVFE----- 2202
Cdd:pfam05622   93 EKEVLE----LQHRNEELTSLAEEAQALKDEMDiLRESSDKVKKLEAT-----VETYKKKLEDLGdlrRQVKLLEernae 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2203 -----LDL-------VTLRSEKENLTKQIQEKQGQLS-----------ELDKLLSSFKSLLEEKEQAEIQiKEESKTAVE 2259
Cdd:pfam05622  164 ymqrtLQLeeelkkaNALRGQLETYKRQVQELHGKLSeeskkadklefEYKKLEEKLEALQKEKERLIIE-RDTLRETNE 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2260 ML---QNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK--LRARLEADEKKQLCVLQQLKESEHHadll 2334
Cdd:pfam05622  243 ELrcaQLQQAELSQADALLSPSSDPGDNLAAEIMPAEIREKLIRLQHENkmLRLGQEGSYRERLTELQQLLEDANR---- 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2335 kgRVENLERELEIArtNQEHAALEA--ENSKGEVETLKAKIEGMTQSLRGLELDVVTIRsekeNLTNELQKEQERISELE 2412
Cdd:pfam05622  319 --RKNELETQNRLA--NQRILELQQqvEELQKALQEQGSKAEDSSLLKQKLEEHLEKLH----EAQSELQKKKEQIEELE 390

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 55770834   2413 IINSS--------FENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNER 2453
Cdd:pfam05622  391 PKQDSnlaqkideLQEALRKKDEDMKAMEERYKKYVEKAKSVIKTLDPK 439
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 16-567 7.08e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 7.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   16 ALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKES 95
Cdd:COG1196  230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   96 QVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADvslnpcntpqkifttpltpsqyysgSKYEDLKEKYNKEV 175
Cdd:COG1196  310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE-------------------------EELEEAEAELAEAE 364

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  176 EERKRLEAEVKALQAKKASQTlpqatmnhRDIARHQASSSVFSWQQEKTPSHLSSNSQRtpirrdfsasyfsgeqevtps 255
Cdd:COG1196  365 EALLEAEAELAEAEEELEELA--------EELLEALRAAAELAAQLEELEEAEEALLER--------------------- 415

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  256 RSTLQIGKRDANSSFFDNSSsphLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKV 335
Cdd:COG1196  416 LERLEEELEELEEALAELEE---EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  336 LNkcRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQ----------NAESARCSLEQKIKEKEKEFQEELSRQQR 405
Cdd:COG1196  493 LL--LLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLKAAK 570

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  406 ----SFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSM 481
Cdd:COG1196  571 agraTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  482 EEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVA 561
Cdd:COG1196  651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730


                 ....*.
gi 55770834  562 DLEKQR 567
Cdd:COG1196  731 EAEREE 736
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2573-2808 7.15e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 7.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2573 QSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELsgekNRLAGELQL 2652
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL----AELEKEIAE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2653 LLEEIKSSKDQLKEL------TLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQ 2726
Cdd:COG4942   95 LRAELEAQKEELAELlralyrLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2727 TYREKLTSKEEclssqkleidllksSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLE 2806
Cdd:COG4942  175 ELEALLAELEE--------------ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                 ..
gi 55770834 2807 EE 2808
Cdd:COG4942  241 ER 242
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 19-674 7.67e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 7.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     19 KIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRE----NQRLME---ICESLEKTKQKISHELQ 91
Cdd:TIGR04523   34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQikdlNDKLKKnkdKINKLNSDLSKINSEIK 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     92 VKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTpsqyysgsKYEDLKEKY 171
Cdd:TIGR04523  114 NDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELN--------LLEKEKLNI 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    172 NKEVE----ERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTpshlssnsqrtpirrDFSASYFS 247
Cdd:TIGR04523  186 QKNIDkiknKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEIN---------------EKTTEISN 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    248 GEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELE-LRLQGHEKEMKGQV----NKFQELQLQL 322
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNnQKEQDWNKELKSELknqeKKLEEIQNQI 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    323 ---EKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEE 399
Cdd:TIGR04523  331 sqnNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    400 lsrqQRSFQTLDQEciqmKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRR 479
Cdd:TIGR04523  411 ----DEQIKKLQQE----KELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQ 482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    480 SMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLA 559
Cdd:TIGR04523  483 NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKE 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    560 VADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFscwKSENEKLltqmESEKEN 639
Cdd:TIGR04523  563 IDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKA---KKENEKL----SSIIKN 635

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 55770834    640 LQSKINHLETCLKtqQIKSHEYNERVRTLEMDREN 674
Cdd:TIGR04523  636 IKSKKNKLKQEVK--QIKETIKEIRNKWPEIIKKI 668
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2116-2351 7.91e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 7.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2116 QLRRGIEKLRVRIEaDEKKQLHIAE-KLKERERENDSLKDKVENLERELQMSEENQELVILDAE--NSKAEVETLKTQIE 2192
Cdd:COG3206  172 EARKALEFLEEQLP-ELRKELEEAEaALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAElaEAEARLAALRAQLG 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2193 EMARSLKVFELDlvtlrSEKENLTKQIQEKQGQLSELDKLLS----SFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKEL 2268
Cdd:COG3206  251 SGPDALPELLQS-----PVIQQLRAQLAELEAELAELSARYTpnhpDVIALRAQIAALRAQLQQEAQRILASLEAELEAL 325

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2269 NEAVAalcgdqeimkateqsldppieeehQLRNSIEKLRARLEADEKKQlcvlQQLKEsehhadllkgrvenLERELEIA 2348
Cdd:COG3206  326 QAREA------------------------SLQAQLAQLEARLAELPELE----AELRR--------------LEREVEVA 363


                 ...
gi 55770834 2349 RTN 2351
Cdd:COG3206  364 REL 366
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2612-2825 8.01e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 8.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2612 NKMTAKETELQREMHEMAQKTAELQEeLSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGK 2691
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAA-LKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2692 VREEIAEYQLRLHEAEKKHQ----ALLLDTNKQYEVEIQTYREKLTSKEeclssQKLEIDLLKSSKEELNNSLKATTQIL 2767
Cdd:COG4942   99 LEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPA-----RREQAEELRADLAELAALRAELEAER 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 55770834 2768 EELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2825
Cdd:COG4942  174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
46 PHA02562
endonuclease subunit; Provisional
 1923-2117 8.14e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.01  E-value: 8.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1923 ADLEVVQTEKLCLEKDNENKqkvIVCLEEELSVVTSERNQLRGELdtmSKKTTALDQLSEKMKEKTQELESHQS--ECLH 2000
Cdd:PHA02562  216 ARKQNKYDELVEEAKTIKAE---IEELTDELLNLVMDIEDPSAAL---NKLNTAAAKIKSKIEQFQKVIKMYEKggVCPT 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2001 CIQVAEAEVKEKTELLQTLSSDVSELLKDKTHlQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS 2080
Cdd:PHA02562  290 CTQQISEGPDRITKIKDKLKELQHSLEKLDTA-IDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE 368

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 55770834  2081 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQL 2117
Cdd:PHA02562  369 ELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHR 405
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2005-2185 8.38e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.82  E-value: 8.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2005 AEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSE--- 2081
Cdd:COG3883   14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGErar 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2082 SDYEKLNVSKALEAALVEK--GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENL 2159
Cdd:COG3883   94 ALYRSGGSVSYLDVLLGSEsfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                        170       180
                 ....*....|....*....|....*.
gi 55770834 2160 ERelQMSEENQELVILDAENSKAEVE 2185
Cdd:COG3883  174 EA--QQAEQEALLAQLSAEEAAAEAQ 197
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2127-2275 8.99e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.76  E-value: 8.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2127 RIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEM--ARSLKVFELD 2204
Cdd:COG1579   18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnNKEYEALQKE 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 55770834 2205 LVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAAL 2275
Cdd:COG1579   98 IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2160-2493 9.29e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 9.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2160 ERELQMSEENQELVILD---AENSKAEVETLKTQIEEMARSLKVFELDL-----VTLRSEKENLTKQIqekqgqlseLDK 2231
Cdd:COG3206   86 QIEILKSRPVLERVVDKlnlDEDPLGEEASREAAIERLRKNLTVEPVKGsnvieISYTSPDPELAAAV---------ANA 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2232 LLSSFKSLLEEKEQaeiqikEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPiEEEHQLRNSIEKLRARLE 2311
Cdd:COG3206  157 LAEAYLEQNLELRR------EEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLS-EEAKLLLQQLSELESQLA 229

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2312 AdekkqlcVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALeaensKGEVETLKAKIEGMTQSLRGLELDVVTIR 2391
Cdd:COG3206  230 E-------ARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQL-----RAQLAELEAELAELSARYTPNHPDVIALR 297

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2392 SEKENLTNELQKEQERIseleiinssfeniLQEKEQEkvqmkeksstaMEMLQTQLKELNERVAALHNDQEACKAKEQ-- 2469
Cdd:COG3206  298 AQIAALRAQLQQEAQRI-------------LASLEAE-----------LEALQAREASLQAQLAQLEARLAELPELEAel 353

                        330       340
                 ....*....|....*....|....*
gi 55770834 2470 -NLSSQVECLELEKAQLLQGLDEAK 2493
Cdd:COG3206  354 rRLEREVEVARELYESLLQRLEEAR 378
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1910-2453 9.36e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.96  E-value: 9.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1910 EKASIEHEALYLEADLEVVQTEKLCLEKDNE--NKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQL------- 1980
Cdd:TIGR00618  254 EQLKKQQLLKQLRARIEELRAQEAVLEETQEriNRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLlmkraah 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   1981 ---SEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQ--TLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELE 2055
Cdd:TIGR00618  334 vkqQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQqhTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATID 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2056 NQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRgIEKLRVRIEADEKKQ 2135
Cdd:TIGR00618  414 TRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-KEQIHLQETRKKAVV 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2136 LHIAEKLKEREREndsLKDKVENLERELQMSEENQ------ELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Cdd:TIGR00618  493 LARLLELQEEPCP---LCGSCIHPNPARQDIDNPGpltrrmQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQ 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQL-------------KELNEAVAALC 2276
Cdd:TIGR00618  570 QSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQdlqdvrlhlqqcsQELALKLTALH 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2277 GDQE-------------IMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQL---CVLQQLKESEHH----ADLLKG 2336
Cdd:TIGR00618  650 ALQLtltqervrehalsIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTllrELETHIEEYDREfneiENASSS 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2337 RVENLERELEIARTNQEHA------ALEAENSKGEVETLKAKIEGMT-QSLRGLELDVVTIRSEKENLTNEL-----QKE 2404
Cdd:TIGR00618  730 LGSDLAAREDALNQSLKELmhqartVLKARTEAHFNNNEEVTAALQTgAELSHLAAEIQFFNRLREEDTHLLktleaEIG 809

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 55770834   2405 QERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEmLQTQLKELNER 2453
Cdd:TIGR00618  810 QEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGE-ITHQLLKYEEC 857
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2141-2309 1.08e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 1.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2141 KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE--NLTKQ 2218
Cdd:COG1579   18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyeALQKE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2219 IQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEhq 2298
Cdd:COG1579   98 IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPE-- 175

                        170
                 ....*....|.
gi 55770834 2299 LRNSIEKLRAR 2309
Cdd:COG1579  176 LLALYERIRKR 186
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 281-990 1.23e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.71  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    281 DQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKV----------ELIEKEKVLNKCRDELVRTTAQY 350
Cdd:pfam05483   88 EKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLkleeeiqenkDLIKENNATRHLCNLLKETCARS 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    351 DQASTKYTALEQKLKKLTEDLSCQ-----------RQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Cdd:pfam05483  168 AEKTKKYEYEREETRQVYMDLNNNiekmilafeelRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLI 247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499
Cdd:pfam05483  248 QITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTIC 327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    500 REVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKlavadlekqrdcsqdlLKKREH 579
Cdd:pfam05483  328 QLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITME----------------LQKKSS 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    580 HIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEkenlQSKINHLETCLKTQQIKSH 659
Cdd:pfam05483  392 ELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAR----EKEIHDLEIQLTAIKTSEE 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    660 EYNERVRTLEMDRENlsVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFsdQKHQKEIENMCLKTSQLTGQVEDLEHKL 739
Cdd:pfam05483  468 HYLKEVEDLKTELEK--EKLKNIELTAHCDKLLLENKELTQEASDMTLEL--KKHQEDIINCKKQEERMLKQIENLEEKE 543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    740 QLLSNEImdkdrcyQDLHAEYESLRDLLKSK-DASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEA 818
Cdd:pfam05483  544 MNLRDEL-------ESVREEFIQKGDEVKCKlDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQE 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    819 DQSPKNSAILQN--------RVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETsqriSKLQE 890
Cdd:pfam05483  617 NKALKKKGSAENkqlnayeiKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEA----VKLQK 692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    891 DTSAH-QNVVAETLSALENKEKELqllnDKVETEQAEIQELKKSNHLLEDSLKelQLLSETLSLEKKEMSSIISLNKREI 969
Cdd:pfam05483  693 EIDKRcQHKIAEMVALMEKHKHQY----DKIIEERDSELGLYKNKEQEQSSAK--AALEIELSNIKAELLSLKKQLEIEK 766

                          730       740
                   ....*....|....*....|.
gi 55770834    970 EELTQENGTLKEINASLNQEK 990
Cdd:pfam05483  767 EEKEKLKMEAKENTAILKDKK 787
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 2270-2840 1.41e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 44.36  E-value: 1.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRV-------ENLE 2342
Cdd:pfam07111   56 EGSQALSQQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALagaemvrKNLE 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2343 ----REL-EIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL-------DVVTIRSEKENLTNELQKEQERISE 2410
Cdd:pfam07111  136 egsqRELeEIQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLETkrageakQLAEAQKEAELLRKQLSKTQEELEA 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2411 LEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTqLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLD 2490
Cdd:pfam07111  216 QVTLVESLRKYVGEQVPPEVHSQTWELERQELLDT-MQHLQEDRADLQATVELLQVRVQSLTHMLALQEEELTRKIQPSD 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2491 EAKNNYIVLQSSVNGLIQE------VEDGKQKLEKKDE------EISRLKNQIQDQEQ--------LVSKLSQVEGEHQL 2550
Cdd:pfam07111  295 SLEPEFPKKCRSLLNRWREkvfalmVQLKAQDLEHRDSvkqlrgQVAELQEQVTSQSQeqailqraLQDKAAEVEVERMS 374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2551 WKEQNLELRnltvELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHE--- 2627
Cdd:pfam07111  375 AKGLQMELS----RAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVHTikg 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2628 -MAQKTAELQ-----------------------EELSGEKNRLAGELQL----LLEEIKSSKDQLKELTLENSELKKSLD 2679
Cdd:pfam07111  451 lMARKVALAQlrqescpppppappvdadlslelEQLREERNRLDAELQLsahlIQQEVGRAREQGEAERQQLSEVAQQLE 530

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2680 CMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEID-LLKSSKEELNN 2758
Cdd:pfam07111  531 QELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYGQALQEKVAEVETRLREQLSDTKrRLNEARREQAK 610

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2759 SLKATTQILEELKKTKMDNlKYVNQLKKENERAQGKMklLIKSCKQLEEEKEILQKELSQ--LQAAQEKQKTGTVMDTKV 2836
Cdd:pfam07111  611 AVVSLRQIQHRATQEKERN-QELRRLQDEARKEEGQR--LARRVQELERDKNLMLATLQQegLLSRYKQQRLLAVLPSGL 687


                   ....
gi 55770834   2837 DELT 2840
Cdd:pfam07111  688 DKKS 691
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2174-2729 1.46e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2174 ILDAENSKAEVETLKTQIEemarslkvfelDLVTLRSEKENLTKQIQekqgQLSELDKLLSSFKSLLEEKEQAEIQIK-- 2251
Cdd:COG4913  217 MLEEPDTFEAADALVEHFD-----------DLERAHEALEDAREQIE----LLEPIRELAERYAAARERLAELEYLRAal 281

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2252 --EESKTAVEMLQNQLKELNEAVAALcgDQEIMKATEQsldppieeEHQLRNSIEKLRARLEADEkkqlcvLQQLKESEH 2329
Cdd:COG4913  282 rlWFAQRRLELLEAELEELRAELARL--EAELERLEAR--------LDALREELDELEAQIRGNG------GDRLEQLER 345

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2330 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKI----EGMTQSLRGLELDVVTIRSEKENLTNELQKEQ 2405
Cdd:COG4913  346 EIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAaallEALEEELEALEEALAEAEAALRDLRRELRELE 425

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2406 ERISELE----IINSSFENILQEKEQ-------------EKVQMKEKSS---TAMEML---------------------- 2443
Cdd:COG4913  426 AEIASLErrksNIPARLLALRDALAEalgldeaelpfvgELIEVRPEEErwrGAIERVlggfaltllvppehyaaalrwv 505

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2444 -QTQLKE-LN-ERVAALHNDQEACKAKEQNLSSQVE---------------------CLE-------LEKAQLLQGLdeA 2492
Cdd:COG4913  506 nRLHLRGrLVyERVRTGLPDPERPRLDPDSLAGKLDfkphpfrawleaelgrrfdyvCVDspeelrrHPRAITRAGQ--V 583

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2493 KNNYIVLQSSVNGLIQEV----EDGKQKLEKKDEEISRLKNQIQDQEQLVSKLsqvEGEHQLWKEQNLELRNLTVELEQK 2568
Cdd:COG4913  584 KGNGTRHEKDDRRRIRSRyvlgFDNRAKLAALEAELAELEEELAEAEERLEAL---EAELDALQERREALQRLAEYSWDE 660

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2569 IQVlqsknASLQDTLEVLQSSYKNLENE-LELTKMDkmsfvEKVNKMTAKETELQREmhemaqktaelQEELSGEKNRLA 2647
Cdd:COG4913  661 IDV-----ASAEREIAELEAELERLDASsDDLAALE-----EQLEELEAELEELEEE-----------LDELKGEIGRLE 719

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2648 GELQLLLEEIKSSKDQLKELT-LENSELKKSLDCMHKDQV--EKEGKVRE----EIAEYQLRLHEAEKKHQALLLDTNKQ 2720
Cdd:COG4913  720 KELEQAEEELDELQDRLEAAEdLARLELRALLEERFAAALgdAVERELREnleeRIDALRARLNRAEEELERAMRAFNRE 799


                 ....*....
gi 55770834 2721 YEVEIQTYR 2729
Cdd:COG4913  800 WPAETADLD 808
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2625-2787 1.47e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.08  E-value: 1.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2625 MHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDcmhkdqvEKEgkvrEEIAEYQLRLH 2704
Cdd:COG2433  383 EELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELE-------EKD----ERIERLERELS 451

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2705 EAEKkhqallldtnkqyeveiQTYREKLTSKEecLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKT-KMDN------ 2777
Cdd:COG2433  452 EARS-----------------EERREIRKDRE--ISRLDREIERLERELEEERERIEELKRKLERLKELwKLEHsgelvp 512

                        170
                 ....*....|
gi 55770834 2778 LKYVNQLKKE 2787
Cdd:COG2433  513 VKVVEKFTKE 522
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2346-2862 1.53e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 1.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2346 EIARTNQEHAALEA-ENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQE 2424
Cdd:pfam12128  222 QVEHWIRDIQAIAGiMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2425 K----EQEKVQMKEKSSTA---MEMLQTQLKE-LNERVAALHNDQEackaKEQNLSSQVECLELEKAQLLQGLDEAKNNY 2496
Cdd:pfam12128  302 KrdelNGELSAADAAVAKDrseLEALEDQHGAfLDADIETAAADQE----QLPSWQSELENLEERLKALTGKHQDVTAKY 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2497 IVLQSSVNG-LIQEVEDGKQKLEKKDEEISRLKNQIQDQ-EQLVSKL-SQVEGEHQLWKEQ-----------NLELRNLT 2562
Cdd:pfam12128  378 NRRRSKIKEqNNRDIAGIKDKLAKIREARDRQLAVAEDDlQALESELrEQLEAGKLEFNEEeyrlksrlgelKLRLNQAT 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2563 VELEQKIQVLQSKNAsLQDTLEVLQSSYKNLEN-ELELTKMDKMSfvekvNKMTAKETELQREMHEMAQKTAELQEELSG 2641
Cdd:pfam12128  458 ATPELLLQLENFDER-IERAREEQEAANAEVERlQSELRQARKRR-----DQASEALRQASRRLEERQSALDELELQLFP 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2642 EKNRLageLQLLLEEIKSSKDQLKELTleNSELKKSLDCmhkDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNK-- 2719
Cdd:pfam12128  532 QAGTL---LHFLRKEAPDWEQSIGKVI--SPELLHRTDL---DPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEElr 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2720 ----QYEVEIQTYREKLTSKEECLSSQKLEIDllKSSKEElnnSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKm 2795
Cdd:pfam12128  604 erldKAEEALQSAREKQAAAEEQLVQANGELE--KASREE---TFARTALKNARLDLRRLFDEKQSEKDKKNKALAERK- 677

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 55770834   2796 KLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTgtvmdtkvdELTTEIKELKETLEEKTKEADEYLD 2862
Cdd:pfam12128  678 DSANERLNSLEAQLKQLDKKHQAWLEEQKEQKR---------EARTEKQAYWQVVEGALDAQLALLK 735
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1761-2311 1.66e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.12  E-value: 1.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1761 DFLGNQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENS 1840
Cdd:PRK01156  177 MLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYES 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1841 DLSEKLEYFSCDHQELLQRVETSEGLNsDLEMHADKSSREDIGDNVAKVNDswkerFLDVENELSRIRSEKASIeHEALY 1920
Cdd:PRK01156  257 EIKTAESDLSMELEKNNYYKELEERHM-KIINDPVYKNRNYINDYFKYKND-----IENKKQILSNIDAEINKY-HAIIK 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1921 LEADLEVVQTEKLCLEKDNENKQKvivcleeelsvvtsERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLH 2000
Cdd:PRK01156  330 KLSVLQKDYNDYIKKKSRYDDLNN--------------QILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISE 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2001 CIQVAEAE----VKEKTEL---LQTLSSDVSELLKDKTHLQEKLQSLEKDSQALS-LTKCELENQIAQLNKEKELLVKES 2072
Cdd:PRK01156  396 ILKIQEIDpdaiKKELNEInvkLQDISSKVSSLNQRIRALRENLDELSRNMEMLNgQSVCPVCGTTLGEEKSNHIINHYN 475

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2073 ESLqARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQ-EEVHQLRRGIEKLRVRIEADEKKQLHIAEK-LKEREREND 2150
Cdd:PRK01156  476 EKK-SRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEiNKSINEYNKIESARADLEDIKIKINELKDKhDKYEEIKNR 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2151 SLKDKVENLE-RELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSEL 2229
Cdd:PRK01156  555 YKSLKLEDLDsKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNK 634

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2230 DKLLSSFKSLLEEKEQAEIQIKEESKTavemLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRAR 2309
Cdd:PRK01156  635 YNEIQENKILIEKLRGKIDNYKKQIAE----IDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTR 710


                  ..
gi 55770834  2310 LE 2311
Cdd:PRK01156  711 IN 712
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2055-2274 1.67e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 1.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2055 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEkgefalrLSSTQEEVHQLRRGIEKLRVRIEADEkk 2134
Cdd:COG3883   15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE-------LEALQAEIDKLQAEIAEAEAEIEERR-- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2135 qlhiaEKLKERER----------------ENDSLKDKVENLERELQMSEENQELV------ILDAENSKAEVETLKTQIE 2192
Cdd:COG3883   86 -----EELGERARalyrsggsvsyldvllGSESFSDFLDRLSALSKIADADADLLeelkadKAELEAKKAELEAKLAELE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2193 EMARSLKVFELDLVTLRSEKENLTKQIQEKQGQL-SELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEA 2271
Cdd:COG3883  161 ALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAeAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 240


                 ...
gi 55770834 2272 VAA 2274
Cdd:COG3883  241 AAA 243
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
828-1172 1.73e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:COG4717  137 LEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLkELQLLSETLSLEkKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Cdd:COG4717  217 EAQEELEELEEELEQLENELEAAALEERLKEARL-LLLIAAALLALL-GLGGSLLSLILTIAGVLFLVLGLLALLFLLLA 294

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  988 QEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNS-----KLECLLNECTS 1062
Cdd:COG4717  295 REKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEleeelQLEELEQEIAA 374

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1063 LCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQnnsKSEAGGLKQEIMTLKEEQNKM 1142
Cdd:COG4717  375 LLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEL---EEELEELEEELEELEEELEEL 451

                        330       340       350
                 ....*....|....*....|....*....|...
gi 55770834 1143 QKEVNDLLQENEQLMK---VMKTKHECQNLESE 1172
Cdd:COG4717  452 REELAELEAELEQLEEdgeLAELLQELEELKAE 484
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
2014-2271 1.83e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2014 ELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKAL 2093
Cdd:COG4372   24 ILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEEL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2094 EAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELV 2173
Cdd:COG4372  104 ESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQ 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2174 ILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEE 2253
Cdd:COG4372  184 ALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEEL 263

                        250
                 ....*....|....*...
gi 55770834 2254 SKTAVEMLQNQLKELNEA 2271
Cdd:COG4372  264 ELAILVEKDTEEEELEIA 281
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2293-2713 1.94e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2293 IEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAE--NSKGEVETLK 2370
Cdd:COG4717   73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAElaELPERLEELE 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2371 AKIegmtQSLRGLELDVVTIRSEKENLTNELQKEQERISE--LEIINSSFENiLQEKEQEKVQMKEKSSTAMEMLQTQLK 2448
Cdd:COG4717  153 ERL----EELRELEEELEELEAELAELQEELEELLEQLSLatEEELQDLAEE-LEELQQRLAELEEELEEAQEELEELEE 227

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2449 ELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLK 2528
Cdd:COG4717  228 ELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL 307

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2529 NQIQDQEQLVS-KLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEvLQSSYKNLENELELTKMDKMSF 2607
Cdd:COG4717  308 QALPALEELEEeELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ-LEELEQEIAALLAEAGVEDEEE 386

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2608 VEKVNKMTAKETELQREMHEMAQKTAELQEELS-----GEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMH 2682
Cdd:COG4717  387 LRAALEQAEEYQELKEELEELEEQLEELLGELEelleaLDEEELEEELEELEEELEELEEELEELREELAELEAELEQLE 466

                        410       420       430
                 ....*....|....*....|....*....|.
gi 55770834 2683 KDqvEKEGKVREEIAEYQLRLHEAEKKHQAL 2713
Cdd:COG4717  467 ED--GELAELLQELEELKAELRELAEEWAAL 495
PRK12705 PRK12705
hypothetical protein; Provisional
 2687-2818 2.82e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 43.16  E-value: 2.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2687 EKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEV-------EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNS 2759
Cdd:PRK12705   34 EAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQearrereELQREEERLVQKEEQLDARAEKLDNLENQLEEREKA 113

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 55770834  2760 LKATTQILEELKKTKMDNLKYVNQLKKENERAQgkmkLLIKSCKQLEEEKEILQKELSQ 2818
Cdd:PRK12705  114 LSARELELEELEKQLDNELYRVAGLTPEQARKL----LLKLLDAELEEEKAQRVKKIEE 168
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
2574-2855 3.66e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 42.21  E-value: 3.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2574 SKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELsgeknrlagelQLL 2653
Cdd:COG1340    1 SKTDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKR-----------DEL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2654 LEEIKSSKDQLKELTLENSELKKSLDcMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEV--EIQTYREK 2731
Cdd:COG1340   70 NEKVKELKEERDELNEKLNELREELD-ELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEEKELveKIKELEKE 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2732 LTSKEECLSSQK------LEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQL 2805
Cdd:COG1340  149 LEKAKKALEKNEklkelrAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADEL 228

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 55770834 2806 EEEKEILQKELSQLQAAQEKQKTGTvMDTKVDELTTEIKELKETLEEKTK 2855
Cdd:COG1340  229 HEEIIELQKELRELRKELKKLRKKQ-RALKREKEKEELEEKAEEIFEKLK 277
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 32-195 3.73e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 3.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   32 KEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENqrlmeicESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQI 111
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL-------AALERRIAALARRIRALEQELAALEAELAELEKEI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  112 EKLEQELKRCKSELERSQQAAQsadvsLNPCNTPQKIFTTPLTPSQYYSGSKY------------EDLKEKYNKEVEERK 179
Cdd:COG4942   93 AELRAELEAQKEELAELLRALY-----RLGRQPPLALLLSPEDFLDAVRRLQYlkylaparreqaEELRADLAELAALRA 167

                        170
                 ....*....|....*.
gi 55770834  180 RLEAEVKALQAKKASQ 195
Cdd:COG4942  168 ELEAERAELEALLAEL 183
Leu_zip pfam15294
Leucine zipper; This family includes Leucine zipper transcription factor-like protein 1 ...
 2779-2885 3.81e-03

Leucine zipper; This family includes Leucine zipper transcription factor-like protein 1 (LZTFL1) and Leucine zipper protein 2 (LUZP2).


Pssm-ID: 464620 [Multi-domain]  Cd Length: 276  Bit Score: 42.00  E-value: 3.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2779 KYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELK----ETLEEKT 2854
Cdd:pfam15294  133 MEIERLKEENEKLKERLKTLESQATQALDEKSKLEKALKDLQKEQGAKKDVKSNLKEISDLEEKMAALKsdleKTLNAST 212

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 55770834   2855 KEADEYLDKYCS----LLISHEKLEKAKEMLETQV 2885
Cdd:pfam15294  213 ALQKSLEEDLAStkheLLKVQEQLEMAEKELEKKF 247
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1946-2116 3.94e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 3.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1946 IVCLEEELSVVTSERNQLRGELDTMSKK----TTALDQLSEKMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTL-- 2019
Cdd:COG3883   18 IQAKQKELSELQAELEAAQAELDALQAEleelNEEYNELQAELEALQAEIDKLQAE----IAEAEAEIEERREELGERar 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2020 -----------------SSDVSELLKD-------KTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESL 2075
Cdd:COG3883   94 alyrsggsvsyldvllgSESFSDFLDRlsalskiADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 55770834 2076 QARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQ 2116
Cdd:COG3883  174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
PLN02939 PLN02939
transferase, transferring glycosyl groups
 2573-2882 3.96e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.97  E-value: 3.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2573 QSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTA----ELQEELSGEKNRLAG 2648
Cdd:PLN02939   49 KRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAaidnEQQTNSKDGEQLSDF 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2649 ELQLLLEEIKSSKdqlKELTLENSELKKSLDCMHKDQVEKEgKVREEIAEYQLRLHEAEKKhqaLLLDTNKQYEVEI-QT 2727
Cdd:PLN02939  129 QLEDLVGMIQNAE---KNILLLNQARLQALEDLEKILTEKE-ALQGKINILEMRLSETDAR---IKLAAQEKIHVEIlEE 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2728 YREKLT--------SKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKmdnlKYVNQLKKENEraqgkmkLLI 2799
Cdd:PLN02939  202 QLEKLRnellirgaTEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETE----ERVFKLEKERS-------LLD 270

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2800 KSCKQLEEEKEILQKELSQLQAAQekqktgtvmdtkVDELTTEIKELKETLEEKTKEADeyldKYCSLLISHEKLEKAKE 2879
Cdd:PLN02939  271 ASLRELESKFIVAQEDVSKLSPLQ------------YDCWWEKVENLQDLLDRATNQVE----KAALVLDQNQDLRDKVD 334


                  ...
gi 55770834  2880 MLE 2882
Cdd:PLN02939  335 KLE 337
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1906-2245 4.30e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.14  E-value: 4.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1906 RIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNEnkqkvivCLEEELSVVTSERNQLRGELdtmsKKTTALD--QLSEK 1983
Cdd:COG5022  811 EYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAE-------VLIQKFGRSLKAKKRFSLLK----KETIYLQsaQRVEL 879

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 1984 MKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCEL--------- 2054
Cdd:COG5022  880 AERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYvklpelnkl 959

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2055 ---ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEAD 2131
Cdd:COG5022  960 hevESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSES 1039

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2132 EKKQlhiaEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAE-VETLKTQIEemARSLKVFELDLVTLRS 2210
Cdd:COG5022 1040 TELS----ILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLEsTENLLKTIN--VKDLEVTNRNLVKPAN 1113

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 55770834 2211 EKENLTKQiQEKQGQLSELDKLLSSFKSLLEEKEQ 2245
Cdd:COG5022 1114 VLQFIVAQ-MIKLNLLQEISKFLSQLVNTLEPVFQ 1147
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 828-1054 4.64e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 4.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEqmhqsfvaetsQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:COG1196  258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE-----------QDIARLEERRRELEERLEELEEELA 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKEL-QLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASL 986
Cdd:COG1196  327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAeEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 55770834  987 NQEKmNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLE 1054
Cdd:COG1196  407 EAEE-ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 2543-2856 4.86e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.57  E-value: 4.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2543 QVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQ 2622
Cdd:pfam07888   56 QREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELE 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2623 REMHEMAQKTAELQEELSGEKnrlagelqlllEEIKSSKDQLKELTLENSELKKSLDcmhkdqvEKEGKVREEIAEYQ-L 2701
Cdd:pfam07888  136 EDIKTLTQRVLERETELERMK-----------ERAKKAGAQRKEEEAERKQLQAKLQ-------QTEEELRSLSKEFQeL 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2702 RLHEAEKKHQALlldtnkQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYV 2781
Cdd:pfam07888  198 RNSLAQRDTQVL------QLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQ 271

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55770834   2782 NQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKtgtvmdTKVDELTTEIKELKETLEEKTKE 2856
Cdd:pfam07888  272 AELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADK------DRIEKLSAELQRLEERLQEERME 340
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
278-463 4.89e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  278 HLLDQLKAQNQE---LRNKINELE-----LRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQ 349
Cdd:COG4913  252 ELLEPIRELAERyaaARERLAELEylraaLRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQ 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  350 YDQAST-KYTALEQKLKKLTEDLSCQRQNAESARcSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQE---- 424
Cdd:COG4913  332 IRGNGGdRLEQLEREIERLERELEERERRRARLE-ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEAlaea 410

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 55770834  425 ---LQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRA 463
Cdd:COG4913  411 eaaLRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA 452
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2036-2292 5.19e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 5.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2036 KLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSEsdyeklnvskaleaalvekgefalrlssTQEEVH 2115
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEA----------------------------LQAEID 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2116 QLRRGIEKLRVRIEADEkkqlhiaEKLKERER----------------ENDSLKDKVENLERELQMSEENQELvILDAEN 2179
Cdd:COG3883   69 KLQAEIAEAEAEIEERR-------EELGERARalyrsggsvsyldvllGSESFSDFLDRLSALSKIADADADL-LEELKA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2180 SKAEVETLKTQIEEMARSLkvfELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVE 2259
Cdd:COG3883  141 DKAELEAKKAELEAKLAEL---EALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217

                        250       260       270
                 ....*....|....*....|....*....|...
gi 55770834 2260 MLQNQLKELNEAVAALCGDQEIMKATEQSLDPP 2292
Cdd:COG3883  218 AAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAG 250
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2521-2726 5.65e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 5.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2521 DEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTvELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELT 2600
Cdd:COG3206  181 EEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLS-ELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2601 KMDKM--SFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKS----SKDQLKELTLENSEL 2674
Cdd:COG3206  260 LQSPViqQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAeleaLQAREASLQAQLAQL 339

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 55770834 2675 KKsldcmhkdQVEKEGKVREEIAEYQLRLHEAEKKHQALLldtNKQYEVEIQ 2726
Cdd:COG3206  340 EA--------RLAELPELEAELRRLEREVEVARELYESLL---QRLEEARLA 380
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2064-2266 5.85e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.15  E-value: 5.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2064 EKELLVKESeslQARLSESDYEKLNVSKALEAALvekgeFALRlsstqEEVHQLRRGIEKLRVRIEADEKKQLHIA---- 2139
Cdd:COG2433  312 KEDLSVEEK---LHLAREYGYDNDHERDALAAAL-----KAYD-----AYKNKFERVEKKVPPDVDRDEVKARVIRglsi 378

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2140 ----EKLKERERENDSLKDKVENLERELQMSEENQELVILDA--ENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEK- 2212
Cdd:COG2433  379 eealEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEqvERLEAEVEELEAELEEKDERIERLERELSEARSEEr 458

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 55770834 2213 ----------------ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEI----QIKEESKTAVEMLQNQLK 2266
Cdd:COG2433  459 reirkdreisrldreiERLERELEEERERIEELKRKLERLKELWKLEHSGELvpvkVVEKFTKEAIRRLEEEYG 532
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2294-2459 6.98e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 6.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2294 EEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAEnskgeVETLKAKI 2373
Cdd:COG1579   31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKE-----IESLKRRI 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834 2374 EGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEiinSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNER 2453
Cdd:COG1579  106 SDLEDEILELMERIEELEEELAELEAELAELEAELEEKK---AELDEELAELEAELEELEAEREELAAKIPPELLALYER 182


                 ....*.
gi 55770834 2454 VAALHN 2459
Cdd:COG1579  183 IRKRKN 188
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 2579-2732 7.05e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.54  E-value: 7.05e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    2579 LQDTLEVLQSSYKNLENELELTKmdkmsfvEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIK 2658
Cdd:smart00787  149 LDENLEGLKEDYKLLMKELELLN-------SIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAKEKLKKLLQEIM 221

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55770834    2659 SSKDQLKELTLENSELKKSLDcmhkdqvekegKVREEIAEYQLRLHEAEKKhqallLDTNKQYEV-EIQTYREKL 2732
Cdd:smart00787  222 IKVKKLEELEEELQELESKIE-----------DLTNKKSELNTEIAEAEKK-----LEQCRGFTFkEIEKLKEQL 280
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
925-1247 7.56e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 7.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   925 AEIQELKKSNHL-LEDSLKELQLLSETLSlEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANY 1003
Cdd:PRK03918  189 ENIEELIKEKEKeLEEVLREINEISSELP-ELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1004 IDEREKSISELSDQYKQEKLI----------------LLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLcENR 1067
Cdd:PRK03918  268 IEELKKEIEELEEKVKELKELkekaeeyiklsefyeeYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEEL-KKK 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1068 KNELEQLKEAFAKEHQEFLTKLAFAEERNQ-----------NLMLELETVQQAlRSEMTDNQNNSKSEAGGLKQEIMTLK 1136
Cdd:PRK03918  347 LKELEKRLEELEERHELYEEAKAKKEELERlkkrltgltpeKLEKELEELEKA-KEEIEEEISKITARIGELKKEIKELK 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  1137 EEQNKMQKE------VNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQL 1210
Cdd:PRK03918  426 KAIEELKKAkgkcpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQL 505

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 55770834  1211 VQLEAMLRNKEL-KLQESEKEKECLQHELQTIRGDLET 1247
Cdd:PRK03918  506 KELEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKS 543
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 280-476 7.59e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 7.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Cdd:COG3883   25 LSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSY 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  360 LEQKL--KKLTEDLScqrqnaesaRCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQA 437
Cdd:COG3883  105 LDVLLgsESFSDFLD---------RLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEA 175

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 55770834  438 ELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENE 476
Cdd:COG3883  176 QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
PRK12704 PRK12704
phosphodiesterase; Provisional
 44-201 8.06e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 8.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    44 LEAALQKQKQKVENEKTEGTNLKRE-----NQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQEL 118
Cdd:PRK12704   33 IKEAEEEAKRILEEAKKEAEAIKKEalleaKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEEL 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   119 KRCKSELERSQQAAQSADVSLnpcntpQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEER---------KRLEAEVKALQ 189
Cdd:PRK12704  113 EKKEKELEQKQQELEKKEEEL------EELIEEQLQELERISGLTAEEAKEILLEKVEEEarheaavliKEIEEEAKEEA 186

                         170
                  ....*....|..
gi 55770834   190 AKKASQTLPQAT 201
Cdd:PRK12704  187 DKKAKEILAQAI 198
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1949-2066 8.48e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 8.48e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKtelLQTLSSDVSELLK 2028
Cdd:smart00787  149 LDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAKEK---LKKLLQEIMIKVK 225

                            90       100       110
                    ....*....|....*....|....*....|....*...
gi 55770834    2029 DKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKE 2066
Cdd:smart00787  226 KLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLE 263
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2602-2814 9.21e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 9.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2602 MDKMSFVEKVNKMTAKETELQREMHEmaQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELK--KSLD 2679
Cdd:PRK05771   56 SEALDKLRSYLPKLNPLREEKKKVSV--KSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEpwGNFD 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2680 C-----------------MHKDQVEK---EGKVREEIAEYQLRLHE-----AEKKHQALLLDTNKQYEVEIQTYREKLTS 2734
Cdd:PRK05771  134 LdlslllgfkyvsvfvgtVPEDKLEElklESDVENVEYISTDKGYVyvvvvVLKELSDEVEEELKKLGFERLELEEEGTP 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834  2735 KEEcLSSQKLEIDLLKSSKEELNNSLKATTQILEELKktkmdnLKYVNQLkkENERAQGKMKLLIKSC------------ 2802
Cdd:PRK05771  214 SEL-IREIKEELEEIEKERESLLEELKELAKKYLEEL------LALYEYL--EIELERAEALSKFLKTdktfaiegwvpe 284

                         250
                  ....*....|..
gi 55770834  2803 KQLEEEKEILQK 2814
Cdd:PRK05771  285 DRVKKLKELIDK 296
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 18-588 9.46e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.75  E-value: 9.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     18 QKIQELEGQLDKLKKEKQQRQFQLDSLEA-ALQKQKQKVENEKTEGTNL---KRENQRLMEICESLEKTKQKISHELQVK 93
Cdd:pfam12128  301 EKRDELNGELSAADAAVAKDRSELEALEDqHGAFLDADIETAAADQEQLpswQSELENLEERLKALTGKHQDVTAKYNRR 380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834     94 ESQVNFQEgqlnsgKKQIEKLEQELKRCKSELERSQQAAQSADVSL-NPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYN 172
Cdd:pfam12128  381 RSKIKEQN------NRDIAGIKDKLAKIREARDRQLAVAEDDLQALeSELREQLEAGKLEFNEEEYRLKSRLGELKLRLN 454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    173 K-EVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQAsssVFSWQQEKTPSHLSSNSQRTPIRRDFSASYfsgEQE 251
Cdd:pfam12128  455 QaTATPELLLQLENFDERIERAREEQEAANAEVERLQSELR---QARKRRDQASEALRQASRRLEERQSALDEL---ELQ 528

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    252 VTPSRSTL-------------QIGKRDANSSFFDNSSSPHLLDQLKAQ----------------------NQELRNKINE 296
Cdd:pfam12128  529 LFPQAGTLlhflrkeapdweqSIGKVISPELLHRTDLDPEVWDGSVGGelnlygvkldlkridvpewaasEEELRERLDK 608

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    297 LELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVR---------------TTAQYDQASTKYTALE 361
Cdd:pfam12128  609 AEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRlfdekqsekdkknkaLAERKDSANERLNSLE 688

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    362 QKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSF-QTLDQECIQMKARLTQELQQAKNMHNVLQAELD 440
Cdd:pfam12128  689 AQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLkAAIAARRSGAKAELKALETWYKRDLASLGVDPD 768

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834    441 KLTSVKQQLENnleeFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREV----CHLEAELKNIKQCL 516
Cdd:pfam12128  769 VIAKLKREIRT----LERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELqqqlARLIADTKLRRAKL 844

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 55770834    517 NQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADlekQRDCSQDLLKKREHHIEQLNDKL 588
Cdd:pfam12128  845 EMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGE---RLAQLEDLKLKRDYLSESVKKYV 913
pepcterm_ChnLen TIGR03007
polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Members of this ...
 2215-2442 9.85e-03

polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Members of this protein family belong to the family of polysaccharide chain length determinant proteins (pfam02706). All are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria, and are found near the epsH homolog that is the putative exosortase gene. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274386 [Multi-domain]  Cd Length: 498  Bit Score: 41.58  E-value: 9.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2215 LTKQIQEKQGQLSELDKLLSSFKSlleEK----EQAEIQIKEESKTAVEMLQNQLKELNEAVAAL------CGDQEIMKA 2284
Cdd:TIGR03007  166 IDEQIKTYEKKLEAAENRLKAFKQ---ENggilPDQEGDYYSEISEAQEELEAARLELNEAIAQRdalkrqLGGEEPVLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2285 TEQSLDPPieeehQLRNSIEKLRARLEAdekkqlcvlQQLKESEHHADllkgrVENLERELEIARTNQEHAALEAENSKG 2364
Cdd:TIGR03007  243 AGSSVANS-----ELDGRIEALEKQLDA---------LRLRYTDKHPD-----VIATKREIAQLEEQKEEEGSAKNGGPE 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55770834   2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEK------VQMKEKSST 2438
Cdd:TIGR03007  304 RGEIANPVYQQLQIELAEAEAEIASLEARVAELTARIERLESLLRTIPEVEAELTQLNRDYEVNKsnyeqlLTRRESAEV 383


                   ....
gi 55770834   2439 AMEM 2442
Cdd:TIGR03007  384 SKQM 387
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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