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Conserved domains on  [gi|5533285|gb|AAD45106|]
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polyprotein, partial [Hepacivirus hominis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HCV_env super family cl03255
Hepatitis C virus envelope glycoprotein E1;
1-54 1.57e-24

Hepatitis C virus envelope glycoprotein E1;


The actual alignment was detected with superfamily member pfam01539:

Pssm-ID: 110536  Cd Length: 190  Bit Score: 90.71  E-value: 1.57e-24
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 5533285      1 TTALVVSQLLRIPQADMDMVTGAHWGVLAGLAYYSMVGNWAKVFIVMLLFAGVD 54
Cdd:pfam01539 137 TATMILAYALRVPEAVLDIIAGAHWGVLFGLAYFSMQGAWAKVLVILLLFAGVD 190
HCV_NS1 super family cl03263
Hepatitis C virus non-structural protein E2/NS1; The hypervariable region of the E2/NS1 region ...
 58-90 1.28e-11

Hepatitis C virus non-structural protein E2/NS1; The hypervariable region of the E2/NS1 region of hepatitis C virus varies greatly between viral isolates. E2 is thought to encode a structurally unconstrained envelope protein.


The actual alignment was detected with superfamily member pfam01560:

Pssm-ID: 110557  Cd Length: 344  Bit Score: 58.71  E-value: 1.28e-11
                          10        20        30
                  ....*....|....*....|....*....|...
gi 5533285     58 YVTGGTAARSTGGLVSMFSPGPSQHIQLINTNG 90
Cdd:pfam01560   1 HVTGGSAARTTRGLVSLFSPGAKQNIQLINTNG 33
 
Name Accession Description Interval E-value
HCV_env pfam01539
Hepatitis C virus envelope glycoprotein E1;
1-54 1.57e-24

Hepatitis C virus envelope glycoprotein E1;


Pssm-ID: 110536  Cd Length: 190  Bit Score: 90.71  E-value: 1.57e-24
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 5533285      1 TTALVVSQLLRIPQADMDMVTGAHWGVLAGLAYYSMVGNWAKVFIVMLLFAGVD 54
Cdd:pfam01539 137 TATMILAYALRVPEAVLDIIAGAHWGVLFGLAYFSMQGAWAKVLVILLLFAGVD 190
HCV_NS1 pfam01560
Hepatitis C virus non-structural protein E2/NS1; The hypervariable region of the E2/NS1 region ...
 58-90 1.28e-11

Hepatitis C virus non-structural protein E2/NS1; The hypervariable region of the E2/NS1 region of hepatitis C virus varies greatly between viral isolates. E2 is thought to encode a structurally unconstrained envelope protein.


Pssm-ID: 110557  Cd Length: 344  Bit Score: 58.71  E-value: 1.28e-11
                          10        20        30
                  ....*....|....*....|....*....|...
gi 5533285     58 YVTGGTAARSTGGLVSMFSPGPSQHIQLINTNG 90
Cdd:pfam01560   1 HVTGGSAARTTRGLVSLFSPGAKQNIQLINTNG 33
 
Name Accession Description Interval E-value
HCV_env pfam01539
Hepatitis C virus envelope glycoprotein E1;
1-54 1.57e-24

Hepatitis C virus envelope glycoprotein E1;


Pssm-ID: 110536  Cd Length: 190  Bit Score: 90.71  E-value: 1.57e-24
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 5533285      1 TTALVVSQLLRIPQADMDMVTGAHWGVLAGLAYYSMVGNWAKVFIVMLLFAGVD 54
Cdd:pfam01539 137 TATMILAYALRVPEAVLDIIAGAHWGVLFGLAYFSMQGAWAKVLVILLLFAGVD 190
HCV_NS1 pfam01560
Hepatitis C virus non-structural protein E2/NS1; The hypervariable region of the E2/NS1 region ...
 58-90 1.28e-11

Hepatitis C virus non-structural protein E2/NS1; The hypervariable region of the E2/NS1 region of hepatitis C virus varies greatly between viral isolates. E2 is thought to encode a structurally unconstrained envelope protein.


Pssm-ID: 110557  Cd Length: 344  Bit Score: 58.71  E-value: 1.28e-11
                          10        20        30
                  ....*....|....*....|....*....|...
gi 5533285     58 YVTGGTAARSTGGLVSMFSPGPSQHIQLINTNG 90
Cdd:pfam01560   1 HVTGGSAARTTRGLVSLFSPGAKQNIQLINTNG 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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