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Conserved domains on  [gi|552909034|ref|WP_023039682|]
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N-acetylglucosamine-specific PTS transporter subunit IIBC [Fusobacterium nucleatum]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PTS-II-BC-nag super family cl37023
PTS system, N-acetylglucosamine-specific IIBC component; This model represents the combined B ...
1-484 0e+00

PTS system, N-acetylglucosamine-specific IIBC component; This model represents the combined B and C domains of the PTS transport system enzyme II specific for N-acetylglucosamine transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, N-acetylglucosamine-specific IIABC component". This family is most closely related to the glucose-specific PTS enzymes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


The actual alignment was detected with superfamily member TIGR01998:

Pssm-ID: 273920 [Multi-domain]  Cd Length: 475  Bit Score: 537.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034    1 MFGYLQKIGKALMVPVAVLPAAAIMLGIGYWidptGWGANSQLAAFLIKAGAAIMDNMAILFAVGVAYGLSKDKDGAAAL 80
Cdd:TIGR01998   1 ILGYFQKLGRALMLPIATLPVAALLLRIGNA----THGADLLVANFFIAAGGAIFDNLGLLFAIGVAIGMSKDNDGAAAL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   81 AGLVAFEIVTTLLSTGAVSQIMGIpQEEVHAAFGKINNQFIGILCGVISGELYNKFHKIELPRFLAFFSGKRFVPIITSV 160
Cdd:TIGR01998  77 AGLVAYFVVTKVLSPPPLAAALGI-KSEINMAFSAWKNVFVGILAGLIAGALYNRFSEIKLPEALSFFSGKRLVPIMAGF 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  161 VMIVVSFILTYIWPIIYGALVTFGTNIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNVAGINDIGRFWGSPDmaya 240
Cdd:TIGR01998 156 VGLVLAALLGYVWPTLYGGIVAFGESISGLGALGAGIYGFLNRLLIPTGLHHALNSVFWFDVAGINDFGNFTGGGD---- 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  241 dlpeiLQGTYHV-GMYQAGFFPIMMFGLLGACVAFIQTSKPENRTKIFSIMVAAGFTSFLTGVTEPIEFAFMFVAPVLYL 319
Cdd:TIGR01998 232 -----LNRFKGIaGMFMAGFFPIMMFGLPAAALAMYHTARPERRKQVGGMLLSVAFASFLTGVTEPLEFSFMFLAPVLYA 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  320 LHALLTGISLFLAASFNWMAGFSFSGGFIDFFLSLKNPNANNPFMLIVLGLVFFVVYYFVFLFVIKAFNLKTPGREESEE 399
Cdd:TIGR01998 307 LHALLTGLSLFIAAMLHWTAGFSFSAGLIDYVLSFNNPTANQPLMLLVQGLVFFALYYVVFRFAIRRFNLKTPGREDEDP 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  400 EKAEAIKVKTTNS---ELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL-VPGVLKPSKESVQVIIGPH 475
Cdd:TIGR01998 387 EGATAAAVTSTGDskmQLAKQYLAALGGHDNLVSIDACITRLRLTLKDTSIVDEPALKALgARGVVKLGKHNLQVILGPL 466

                  ....*....
gi 552909034  476 VEFVATELK 484
Cdd:TIGR01998 467 AEIVAGEMK 475
 
Name Accession Description Interval E-value
PTS-II-BC-nag TIGR01998
PTS system, N-acetylglucosamine-specific IIBC component; This model represents the combined B ...
1-484 0e+00

PTS system, N-acetylglucosamine-specific IIBC component; This model represents the combined B and C domains of the PTS transport system enzyme II specific for N-acetylglucosamine transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, N-acetylglucosamine-specific IIABC component". This family is most closely related to the glucose-specific PTS enzymes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273920 [Multi-domain]  Cd Length: 475  Bit Score: 537.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034    1 MFGYLQKIGKALMVPVAVLPAAAIMLGIGYWidptGWGANSQLAAFLIKAGAAIMDNMAILFAVGVAYGLSKDKDGAAAL 80
Cdd:TIGR01998   1 ILGYFQKLGRALMLPIATLPVAALLLRIGNA----THGADLLVANFFIAAGGAIFDNLGLLFAIGVAIGMSKDNDGAAAL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   81 AGLVAFEIVTTLLSTGAVSQIMGIpQEEVHAAFGKINNQFIGILCGVISGELYNKFHKIELPRFLAFFSGKRFVPIITSV 160
Cdd:TIGR01998  77 AGLVAYFVVTKVLSPPPLAAALGI-KSEINMAFSAWKNVFVGILAGLIAGALYNRFSEIKLPEALSFFSGKRLVPIMAGF 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  161 VMIVVSFILTYIWPIIYGALVTFGTNIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNVAGINDIGRFWGSPDmaya 240
Cdd:TIGR01998 156 VGLVLAALLGYVWPTLYGGIVAFGESISGLGALGAGIYGFLNRLLIPTGLHHALNSVFWFDVAGINDFGNFTGGGD---- 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  241 dlpeiLQGTYHV-GMYQAGFFPIMMFGLLGACVAFIQTSKPENRTKIFSIMVAAGFTSFLTGVTEPIEFAFMFVAPVLYL 319
Cdd:TIGR01998 232 -----LNRFKGIaGMFMAGFFPIMMFGLPAAALAMYHTARPERRKQVGGMLLSVAFASFLTGVTEPLEFSFMFLAPVLYA 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  320 LHALLTGISLFLAASFNWMAGFSFSGGFIDFFLSLKNPNANNPFMLIVLGLVFFVVYYFVFLFVIKAFNLKTPGREESEE 399
Cdd:TIGR01998 307 LHALLTGLSLFIAAMLHWTAGFSFSAGLIDYVLSFNNPTANQPLMLLVQGLVFFALYYVVFRFAIRRFNLKTPGREDEDP 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  400 EKAEAIKVKTTNS---ELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL-VPGVLKPSKESVQVIIGPH 475
Cdd:TIGR01998 387 EGATAAAVTSTGDskmQLAKQYLAALGGHDNLVSIDACITRLRLTLKDTSIVDEPALKALgARGVVKLGKHNLQVILGPL 466

                  ....*....
gi 552909034  476 VEFVATELK 484
Cdd:TIGR01998 467 AEIVAGEMK 475
PRK10255 PRK10255
PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional
1-489 4.22e-105

PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional


Pssm-ID: 182338 [Multi-domain]  Cd Length: 648  Bit Score: 327.21  E-value: 4.22e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   1 MFGYLQKIGKALMVPVAVLPAAAIMLGIGYwidptgwgANSQLAAFLIKAGAAIMDNMAILFAVGVAYGLSKDKDGAAAL 80
Cdd:PRK10255   3 ILGFFQRLGRALQLPIAVLPVAALLLRFGQ--------PDLLNVAFIAQAGGAIFDNLALIFAIGVASSWSKDSAGAAAL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  81 AGLVAFEIVTTLLSTGAVSQIMGIpqeevhaafgkinnqFIGILCGVISGELYNKFHKIELPRFLAFFSGKRFVPIITSV 160
Cdd:PRK10255  75 AGAVGYFVLTKAMVTINPEINMGV---------------LAGIITGLVGGAAYNRWSDIKLPDFLSFFGGKRFVPIATGF 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 161 VMIVVSFILTYIWPIIYGALVTFGTNIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNvagindIGRFWGSPDMAY- 239
Cdd:PRK10255 140 FCLVLAAIFGYVWPPVQHAIHAGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQ------IGEFTNAAGTVFh 213
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 240 ADLPEILQGTYHVGMYQAGFFPIMMFGLLGACVAFIQTSKPENRTKIFSIMVAAGFTSFLTGVTEPIEFAFMFVAPVLYL 319
Cdd:PRK10255 214 GDINRFYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAVTAFLTGVTEPLEFLFMFLAPLLYL 293
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 320 LHALLTGISLFLAASFNWMAGFSFSGGFIDFFLSLKNPNA-NNPFMLIVLGLVFFVVYYFVFLFVIKAFNLKTPGREESE 398
Cdd:PRK10255 294 LHALLTGISLFVATLLGIHAGFSFSAGAIDYALMYNLPAAsQNVWMLLVMGVVFFAIYFVLFSAVIRMFNLKTPGREDKE 373
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 399 EEKAEAIKVKTTN---SELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL-VPGVLKPSKESVQVIIGP 474
Cdd:PRK10255 374 DEIVTEEANSNTEeglTQLATNYIAAVGGTDNLKAIDACITRLRLTVADSARVNDAMCKRLgASGVVKLNKQTIQVIVGA 453
                        490
                 ....*....|....*
gi 552909034 475 HVEFVATELKRILGK 489
Cdd:PRK10255 454 KAESIGDAMKKVVAR 468
PtsG1 COG1263
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific ...
1-476 1.36e-70

Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism];


Pssm-ID: 440875 [Multi-domain]  Cd Length: 463  Bit Score: 231.75  E-value: 1.36e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   1 MFGYLQKIGKALMVPVAVLPAAAIMLGIGYWIDPTGW----GANSQLAAFLIKAGAAIMDNMAILFAVGVAYGLSkdkdG 76
Cdd:COG1263    8 LFRFLQKIGGIFMPPIPVLPAAGLLLGLGALLTNPGLlgegSFLSGTYQILNAAGDAVFYFLPLLFAIGAAKGFG----G 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  77 AAALAGLVAFEIVTTLLST-----GAVSQIMGIPQeevhaafgKINNQ---FIGILCGVISGELyNKFHKIELPRFLAFF 148
Cdd:COG1263   84 NPALAAVIGYLLVHPTLLNayavaGGYISFLGIPT--------LIGYQggvFPGILAGWLAAYL-EKFLKKKLPDALGFF 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 149 sgkrFVPIITSVVMIVVSF-ILTYIWPIIYGALVT-FGTNIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNVAGIN 226
Cdd:COG1263  155 ----FVPILTLLIMVPLALlVIGPIWPPIGNGIAAgLGWIYGLAGAIGGFIYGFLYRLLVPTGLHHGLNPIFWFLLGGTG 230
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 227 DIGRFwgspdmayadlpeilqgtyhvgmyqaGFFPIMMFGLLGACVAFIQTSKPENRTKifSIMVAAGFTSFLTGVTEPI 306
Cdd:COG1263  231 DDGLF--------------------------PILAAAMFGQPGAALAVYLKAKPNKKVK--GLAISAALTAFLTGITEPA 282
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 307 EFAFMFVAPVLYLLHALLTGISLFLAASFNWMAgFSFS-GGFIDfFLSLKNPNANNpFMLIVLGLVFFVVYYFVFLFVIk 385
Cdd:COG1263  283 EFGFNLVAPKLFIAHAIGGGLGGAIAGLLGVKA-FSFGvGGLID-FPSILNPGATN-LLLYLIGLVIAFVYYFVFTFLI- 358
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 386 afnlktpGREESEEEKAEAIKVKTTNSELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKLVPGVLKPSK 465
Cdd:COG1263  359 -------GREDEEEEEKLATKADAKKEEAEAAAAALGGGGGLLLLEADITVLLLTLVDVVIVVVKDVVKLAAAGAVVVGV 431
                        490
                 ....*....|.
gi 552909034 466 ESVQVIIGPHV 476
Cdd:COG1263  432 GGVGAVGGVGG 442
PTS_EIIC pfam02378
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ...
9-326 1.42e-49

Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.


Pssm-ID: 367061  Cd Length: 315  Bit Score: 172.15  E-value: 1.42e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034    9 GKALMVPVAVLPAAAIMLGIGYWIDPTGW------GANSQLAAFLIKAGAAIMDNMAILFAVGVAYGLSKDKDGAAALAG 82
Cdd:pfam02378   1 GDGFMPPIPLLIAGGILLGLGNLPNDTTGlpaggfTGDSPLAEILKQAGSAAFGILPILFAIGIAYGLAGGDGVAGAAGL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   83 LVA--FEIVTTLLSTGAVSQIMGIPqeEVHAAFGKINNQFIGILCGVISGELYNKFHK---IELPRFLAFFSGKRFVPII 157
Cdd:pfam02378  81 IGLlsFNLAAAISVALTAAGLSGGG--NILGIGLGATGVFGAIIPGLLAAYLYNRFEKnitIKLPDSLPFFVGKRFVPII 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  158 TS-VVMIVVSFILTYIWPIIYGALVTFGT-NIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNVAGIndigrfwgsp 235
Cdd:pfam02378 159 TGfVTLLVIGPVLGLIWPAIQGGLNALGLlLIIAGGILGGLIFGFLERLLWPFGLHGAFIAIFWFLPIGG---------- 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  236 dmaYADLPEILQGTYHVGMYQAGFFpIMMFGLLGACVAFIQTSKPENRTKIFSIMVAAGFTSFLTGVTEPIEFAFMFVAP 315
Cdd:pfam02378 229 ---SNPIANQQAYGAGAAHILTGGF-DVMFGGPGATLALYAAAFLFKKSKVKKLLGSAALTPFLFGITEPLEFGFPFVLN 304
                         330
                  ....*....|.
gi 552909034  316 VLYLLHALLTG 326
Cdd:pfam02378 305 PPFFIPAILAG 315
PTS_IIB_glc cd00212
PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: ...
412-487 7.35e-20

PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation


Pssm-ID: 238130 [Multi-domain]  Cd Length: 78  Bit Score: 83.74  E-value: 7.35e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 552909034 412 SELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL--VPGVLKpSKESVQVIIGPHV-EFVATELKRIL 487
Cdd:cd00212    1 EQLAKDILEALGGKENIVSLDHCATRLRLTVKDESKVDEAALKKLggVKGVVK-NGGQYQVIIGPGVaDVYKEAIKLLG 78
 
Name Accession Description Interval E-value
PTS-II-BC-nag TIGR01998
PTS system, N-acetylglucosamine-specific IIBC component; This model represents the combined B ...
1-484 0e+00

PTS system, N-acetylglucosamine-specific IIBC component; This model represents the combined B and C domains of the PTS transport system enzyme II specific for N-acetylglucosamine transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, N-acetylglucosamine-specific IIABC component". This family is most closely related to the glucose-specific PTS enzymes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273920 [Multi-domain]  Cd Length: 475  Bit Score: 537.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034    1 MFGYLQKIGKALMVPVAVLPAAAIMLGIGYWidptGWGANSQLAAFLIKAGAAIMDNMAILFAVGVAYGLSKDKDGAAAL 80
Cdd:TIGR01998   1 ILGYFQKLGRALMLPIATLPVAALLLRIGNA----THGADLLVANFFIAAGGAIFDNLGLLFAIGVAIGMSKDNDGAAAL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   81 AGLVAFEIVTTLLSTGAVSQIMGIpQEEVHAAFGKINNQFIGILCGVISGELYNKFHKIELPRFLAFFSGKRFVPIITSV 160
Cdd:TIGR01998  77 AGLVAYFVVTKVLSPPPLAAALGI-KSEINMAFSAWKNVFVGILAGLIAGALYNRFSEIKLPEALSFFSGKRLVPIMAGF 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  161 VMIVVSFILTYIWPIIYGALVTFGTNIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNVAGINDIGRFWGSPDmaya 240
Cdd:TIGR01998 156 VGLVLAALLGYVWPTLYGGIVAFGESISGLGALGAGIYGFLNRLLIPTGLHHALNSVFWFDVAGINDFGNFTGGGD---- 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  241 dlpeiLQGTYHV-GMYQAGFFPIMMFGLLGACVAFIQTSKPENRTKIFSIMVAAGFTSFLTGVTEPIEFAFMFVAPVLYL 319
Cdd:TIGR01998 232 -----LNRFKGIaGMFMAGFFPIMMFGLPAAALAMYHTARPERRKQVGGMLLSVAFASFLTGVTEPLEFSFMFLAPVLYA 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  320 LHALLTGISLFLAASFNWMAGFSFSGGFIDFFLSLKNPNANNPFMLIVLGLVFFVVYYFVFLFVIKAFNLKTPGREESEE 399
Cdd:TIGR01998 307 LHALLTGLSLFIAAMLHWTAGFSFSAGLIDYVLSFNNPTANQPLMLLVQGLVFFALYYVVFRFAIRRFNLKTPGREDEDP 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  400 EKAEAIKVKTTNS---ELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL-VPGVLKPSKESVQVIIGPH 475
Cdd:TIGR01998 387 EGATAAAVTSTGDskmQLAKQYLAALGGHDNLVSIDACITRLRLTLKDTSIVDEPALKALgARGVVKLGKHNLQVILGPL 466

                  ....*....
gi 552909034  476 VEFVATELK 484
Cdd:TIGR01998 467 AEIVAGEMK 475
PTS-II-BC-glcB TIGR02002
PTS system, glucose-specific IIBC component; This model represents the combined B and C ...
2-487 1.53e-107

PTS system, glucose-specific IIBC component; This model represents the combined B and C domains of the PTS transport system enzyme II specific for glucose transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, glucose-specific IIABC component" while the B. subtilus enzyme also contains an enzyme III domain which appears to act independently of the enzyme II domains. This family is most closely related to the N-acetylglucosamine-specific PTS enzymes (TIGR01998). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273923 [Multi-domain]  Cd Length: 502  Bit Score: 329.05  E-value: 1.53e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034    2 FGYLQKIGKALMVPVAVLPAAAIMLGIG---------YWIDPTGWGANSQLAAFLIKAGAAIMDNMAILFAVGVAYGLSK 72
Cdd:TIGR02002   5 FGQLQKIGKALMLPVAVLPVAGILLGFGnanqnnqvfSFLPFLHMEWIQLVSKVMEAAGGIIFANLPLIFAIGVALGLAG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   73 DKDGAAALAGLVAFEIVTTLLSTGAVSQIMGIPQEEVHAAFGKINNQFIGILCGVISGEL----YNKFHKIELPRFLAFF 148
Cdd:TIGR02002  85 NDGVAGLAALVGYLIMNKTMGVVAGLTLLLIASEIASFASVLGIPTLQTGVFGGIIIGAIaaycYNRFYNIKLPEYLGFF 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  149 SGKRFVPIITSVVMIVVSFILTYIWPIIYGALVTFGTNIAKLGP-VGAGIYGFFNRLLIPVGLHHAVNSVFWFNVAG-IN 226
Cdd:TIGR02002 165 AGKRFVPIITGLAAIVTGIVLSFIWPPVQDALNTFSHWAAYQNPvVAFFIFGFIERSLIPFGLHHIFNAPFWFEFGSyTN 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  227 DIGR-FWGSPDMAYADLPEILQGTyhVGMYQAGFFPIMMFGLLGACVAFIQTSKPENRTKIFSIMVAAGFTSFLTGVTEP 305
Cdd:TIGR02002 245 EAGNlFRGDQPIFMAQLKDGVAFT--AGGFLSGGFPFMMFGLPAAALAIYHSAKPENKKLVGGLMISAALTSFLTGITEP 322
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  306 IEFAFMFVAPVLYLLHALLTGISLFLAASFNWMAGFSFSGGFIDFFLSLKNPNANNPFMLIVLGLVFFVVYYFVFLFVIK 385
Cdd:TIGR02002 323 LEFSFLFVAPILYVIHAILAGLSFPIMILLGVKIGTTFSGGAIDFILYGLLSNRSKAWLFIIVGIGYAIIYYFLFRFLIK 402
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  386 AFNLKTPGREESEEEKaeaiKVKTTNSELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL-VPGVLKPS 464
Cdd:TIGR02002 403 KLNLKTPGREDATAEA----KATGEPSELAFDVVAALGGKENITSLDACITRLRVSVADISKVDVAKLKKLgAAGVLVVG 478
                         490       500
                  ....*....|....*....|...
gi 552909034  465 kESVQVIIGPHVEFVATELKRIL 487
Cdd:TIGR02002 479 -NNVQAIFGPKSDTIKSEMHDII 500
PRK10255 PRK10255
PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional
1-489 4.22e-105

PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional


Pssm-ID: 182338 [Multi-domain]  Cd Length: 648  Bit Score: 327.21  E-value: 4.22e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   1 MFGYLQKIGKALMVPVAVLPAAAIMLGIGYwidptgwgANSQLAAFLIKAGAAIMDNMAILFAVGVAYGLSKDKDGAAAL 80
Cdd:PRK10255   3 ILGFFQRLGRALQLPIAVLPVAALLLRFGQ--------PDLLNVAFIAQAGGAIFDNLALIFAIGVASSWSKDSAGAAAL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  81 AGLVAFEIVTTLLSTGAVSQIMGIpqeevhaafgkinnqFIGILCGVISGELYNKFHKIELPRFLAFFSGKRFVPIITSV 160
Cdd:PRK10255  75 AGAVGYFVLTKAMVTINPEINMGV---------------LAGIITGLVGGAAYNRWSDIKLPDFLSFFGGKRFVPIATGF 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 161 VMIVVSFILTYIWPIIYGALVTFGTNIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNvagindIGRFWGSPDMAY- 239
Cdd:PRK10255 140 FCLVLAAIFGYVWPPVQHAIHAGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQ------IGEFTNAAGTVFh 213
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 240 ADLPEILQGTYHVGMYQAGFFPIMMFGLLGACVAFIQTSKPENRTKIFSIMVAAGFTSFLTGVTEPIEFAFMFVAPVLYL 319
Cdd:PRK10255 214 GDINRFYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAVTAFLTGVTEPLEFLFMFLAPLLYL 293
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 320 LHALLTGISLFLAASFNWMAGFSFSGGFIDFFLSLKNPNA-NNPFMLIVLGLVFFVVYYFVFLFVIKAFNLKTPGREESE 398
Cdd:PRK10255 294 LHALLTGISLFVATLLGIHAGFSFSAGAIDYALMYNLPAAsQNVWMLLVMGVVFFAIYFVLFSAVIRMFNLKTPGREDKE 373
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 399 EEKAEAIKVKTTN---SELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL-VPGVLKPSKESVQVIIGP 474
Cdd:PRK10255 374 DEIVTEEANSNTEeglTQLATNYIAAVGGTDNLKAIDACITRLRLTVADSARVNDAMCKRLgASGVVKLNKQTIQVIVGA 453
                        490
                 ....*....|....*
gi 552909034 475 HVEFVATELKRILGK 489
Cdd:PRK10255 454 KAESIGDAMKKVVAR 468
PRK11089 PRK11089
PTS system glucose-specific transporter subunits IIBC; Provisional
2-483 1.49e-103

PTS system glucose-specific transporter subunits IIBC; Provisional


Pssm-ID: 182955 [Multi-domain]  Cd Length: 477  Bit Score: 317.81  E-value: 1.49e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   2 FGYLQKIGKALMVPVAVLPAAAIMLGIGY----WIDPTgwgaNSQLAAfliKAGAAIMDNMAILFAVGVAYGLSKDkDGA 77
Cdd:PRK11089   6 FANLQKVGKSLMLPVSVLPIAGILLGVGSanfsWLPAV----VSHVMA---EAGGSVFANMPLIFAIGVALGFTNN-DGV 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  78 AALAGLVAFEIVTTLLSTGAvSQIMGIPQEEVHAAFGKINNQFIGILCGVISGELYNKFHKIELPRFLAFFSGKRFVPII 157
Cdd:PRK11089  78 SALAAVVAYGIMVKTMAVVA-PLVLHLPAEEIAAKHLADTGVLGGIIAGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPII 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 158 TSVVMIVVSFILTYIWPIIYGALVTFGTNIAKLGPVGA-GIYGFFNRLLIPVGLHHAVNSVFWFNVAG-INDIGRFWgsp 235
Cdd:PRK11089 157 SGLAAIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAfGIYGFVERSLVPFGLHHIWNVPFQMQIGEyTNAAGQVF--- 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 236 dmaYADLPEILQGTYHVGMYQAGFFpIMMFGLLGACVAFIQTSKPENRTKIFSIMVAAGFTSFLTGVTEPIEFAFMFVAP 315
Cdd:PRK11089 234 ---HGDIPRYMAGDPTAGKLSGGFL-FKMYGLPAAAIAIWHSAKPENRAKVGGIMISAALTSFLTGITEPIEFSFMFVAP 309
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 316 VLYLLHALLTGISLFLAASFNWMAGFSFSGGFIDFFlsLKNPNANNPFMLIVLGLVFFVVYYFVFLFVIKAFNLKTPGRe 395
Cdd:PRK11089 310 ILYIIHAILAGLAFPICILLGMRDGTSFSHGLIDFI--VLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGR- 386
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 396 eseeEKAEAIKVKTTNSELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKLVPGVLKPSKESVQVIIGPH 475
Cdd:PRK11089 387 ----EDETEDAKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVVAGSGVQAIFGTK 462

                 ....*...
gi 552909034 476 VEFVATEL 483
Cdd:PRK11089 463 SDNLKTEM 470
PtsG1 COG1263
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific ...
1-476 1.36e-70

Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism];


Pssm-ID: 440875 [Multi-domain]  Cd Length: 463  Bit Score: 231.75  E-value: 1.36e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   1 MFGYLQKIGKALMVPVAVLPAAAIMLGIGYWIDPTGW----GANSQLAAFLIKAGAAIMDNMAILFAVGVAYGLSkdkdG 76
Cdd:COG1263    8 LFRFLQKIGGIFMPPIPVLPAAGLLLGLGALLTNPGLlgegSFLSGTYQILNAAGDAVFYFLPLLFAIGAAKGFG----G 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  77 AAALAGLVAFEIVTTLLST-----GAVSQIMGIPQeevhaafgKINNQ---FIGILCGVISGELyNKFHKIELPRFLAFF 148
Cdd:COG1263   84 NPALAAVIGYLLVHPTLLNayavaGGYISFLGIPT--------LIGYQggvFPGILAGWLAAYL-EKFLKKKLPDALGFF 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 149 sgkrFVPIITSVVMIVVSF-ILTYIWPIIYGALVT-FGTNIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNVAGIN 226
Cdd:COG1263  155 ----FVPILTLLIMVPLALlVIGPIWPPIGNGIAAgLGWIYGLAGAIGGFIYGFLYRLLVPTGLHHGLNPIFWFLLGGTG 230
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 227 DIGRFwgspdmayadlpeilqgtyhvgmyqaGFFPIMMFGLLGACVAFIQTSKPENRTKifSIMVAAGFTSFLTGVTEPI 306
Cdd:COG1263  231 DDGLF--------------------------PILAAAMFGQPGAALAVYLKAKPNKKVK--GLAISAALTAFLTGITEPA 282
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 307 EFAFMFVAPVLYLLHALLTGISLFLAASFNWMAgFSFS-GGFIDfFLSLKNPNANNpFMLIVLGLVFFVVYYFVFLFVIk 385
Cdd:COG1263  283 EFGFNLVAPKLFIAHAIGGGLGGAIAGLLGVKA-FSFGvGGLID-FPSILNPGATN-LLLYLIGLVIAFVYYFVFTFLI- 358
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 386 afnlktpGREESEEEKAEAIKVKTTNSELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKLVPGVLKPSK 465
Cdd:COG1263  359 -------GREDEEEEEKLATKADAKKEEAEAAAAALGGGGGLLLLEADITVLLLTLVDVVIVVVKDVVKLAAAGAVVVGV 431
                        490
                 ....*....|.
gi 552909034 466 ESVQVIIGPHV 476
Cdd:COG1263  432 GGVGAVGGVGG 442
PRK10110 PRK10110
PTS maltose transporter subunit IICB;
1-488 5.63e-64

PTS maltose transporter subunit IICB;


Pssm-ID: 182245 [Multi-domain]  Cd Length: 530  Bit Score: 216.14  E-value: 5.63e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   1 MFGYLQKIGKALMVPVAVLPAAAIMLGIGY------WIDPTGWGANSQLAA---FLIKAGAAIMDNMAILFAVGVAYGLS 71
Cdd:PRK10110  11 LWEFFQQLGKTFMLPVALLSFCGIMLGIGSslsshdVITLIPFLGNPVLQAiftWMSKIGSFAFSFLPVMFCIAIPLGLA 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  72 KDKDGAAALAGLVAFEIVTtlLSTGAVSQIMGIPQEEVHAAFGKINNQFI--------GILCGVISG----ELYNKFHKI 139
Cdd:PRK10110  91 RENKGVAAFAGFVGYAVMN--LAVNFWLTNKGILPTTDAAVLKANNIQSIlgiqsidtGILGAVIAGiivwMLHERFHNI 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 140 ELPRFLAFFSGKRFVPIITSVVMIVVSFILTYIWPIIYGALVTFGTNIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFW 219
Cdd:PRK10110 169 RLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINSAGDFGPMLFGTGERLLLPFGLHHILVALIR 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 220 FNVAGINDI---GRFWGSPDMAYADL--PEILQGTYHVGMY-QAGFFPIMMFGLLGACVAFIQTSKPENRTKIFSIMVAA 293
Cdd:PRK10110 249 FTDAGGTQEvcgQTVSGALTIFQAQLscPTTHGFSESATRFlSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISG 328
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 294 GFTSFLTGVTEPIEFAFMFVAPVLYLLHALLTGISLFLAASFNWMAGfSFSGGFIDFFL-SLKNPNANNPFMLIVLGLVF 372
Cdd:PRK10110 329 VIACVVGGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIG-NTDGNIIDFVVfGILHGLSTKWYMVPVVAAIW 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 373 FVVYYFVFLFVIKAFNLKTPGREESEEEKAEAIKVKTTNSE--LAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKE 450
Cdd:PRK10110 408 FVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSgyNVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVDV 487
                        490       500       510
                 ....*....|....*....|....*....|....*....
gi 552909034 451 SEIKKL-VPGVLKPSKESVQVIIGPHVEFVATELKRILG 488
Cdd:PRK10110 488 QALKDNrAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMH 526
PTS-IIBC-malX TIGR02004
PTS system, maltose and glucose-specific IIBC component; This model represents a family of PTS ...
4-487 3.82e-58

PTS system, maltose and glucose-specific IIBC component; This model represents a family of PTS enzyme II fused B and C components including and most closely related to the MalX maltose and glucose-specific transporter of E. coli. A pair of paralogous genes from E. coli strain CFT073 score between trusted and noise and may have diverged sufficiently to have an altered substrate specificity. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273924 [Multi-domain]  Cd Length: 517  Bit Score: 200.45  E-value: 3.82e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034    4 YLQKIGKALMVPVAVLPAAAIMLGIGYWIDPTgwgANSQLAAFLIKAGAAI----MDN--------MAILFAVGVAYGLS 71
Cdd:TIGR02004   7 FFQGLGKTFMLPVALLAFMGILLGLGSSFSSE---AMIETIPFLGKPAFKIifqwMSTiglvafayLPVMFAMAIPLGLA 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   72 KDKDGAAALAGLVAFEIVTTLLSTGAVSQIMGIPQEEVHAA-----FGkINNQFIGILCGVISG----ELYNKFHKIELP 142
Cdd:TIGR02004  84 REEKGVAAFSGFVGYTAMNLAINFYLTQTGVLVDPEQLREAgqgmvFG-IQSIDTGVLGAVIVGlivyKLHNRFYTVQMP 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  143 RFLAFFSGKRFVPIITSVVMIVVSFILTYIWPIIYGALVTFGTNIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNV 222
Cdd:TIGR02004 163 DALAFFGGARFVPIISALVLAVVGLVIPLVWPLFALMIMAIGQLIQRSGIFGPFLFGSGERLLLPIGLHHILVAMIRFTE 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  223 AGINDI---GRFWGSPDMAYADLPEILQGTYH---VGMYQAGFFPIMMFGLLGACVAFIQTSKPENRTKIFSIMVAAGFT 296
Cdd:TIGR02004 243 AGGSAVvcgKEVSGALNIFYAELQCNLPISAVpsaTAFLSQGKMPTFLGGLPGAALAMYHCARPANRHKIKALLLSGVVA 322
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  297 SFLTGVTEPIEFAFMFVAPVLYLLHALLTGISLFLAASFNWMAGfSFSGGFIDFFL-SLKNPNANNPFMLIVLGLVFFVV 375
Cdd:TIGR02004 323 CAVGGITEPLEFLFLFVAPLLYLVHAILTGLGFMVMALLGVVIG-NTDGNLIDFLVfGVLQGTYTKWYLVPIVAAIWFVV 401
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  376 YYFVFLFVIKAFNLKTPGREESEEEKAE---AIKVKTTNSELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESE 452
Cdd:TIGR02004 402 YYFVFKTAITTFDLKTPGREKVLDAEEYteqEVAYKKTGGYDAAAILAALGGQENIQSLDNCITRLRLVVADANKVDDAK 481
                         490       500       510
                  ....*....|....*....|....*....|....*.
gi 552909034  453 IKKL-VPGVLKPSKESVQVIIGPHVEFVATELKRIL 487
Cdd:TIGR02004 482 LKQLgALGVVKLDAHNVQVVIGTQVTTVKNQLEMIL 517
PTS_EIIC pfam02378
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ...
9-326 1.42e-49

Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.


Pssm-ID: 367061  Cd Length: 315  Bit Score: 172.15  E-value: 1.42e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034    9 GKALMVPVAVLPAAAIMLGIGYWIDPTGW------GANSQLAAFLIKAGAAIMDNMAILFAVGVAYGLSKDKDGAAALAG 82
Cdd:pfam02378   1 GDGFMPPIPLLIAGGILLGLGNLPNDTTGlpaggfTGDSPLAEILKQAGSAAFGILPILFAIGIAYGLAGGDGVAGAAGL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   83 LVA--FEIVTTLLSTGAVSQIMGIPqeEVHAAFGKINNQFIGILCGVISGELYNKFHK---IELPRFLAFFSGKRFVPII 157
Cdd:pfam02378  81 IGLlsFNLAAAISVALTAAGLSGGG--NILGIGLGATGVFGAIIPGLLAAYLYNRFEKnitIKLPDSLPFFVGKRFVPII 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  158 TS-VVMIVVSFILTYIWPIIYGALVTFGT-NIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNVAGIndigrfwgsp 235
Cdd:pfam02378 159 TGfVTLLVIGPVLGLIWPAIQGGLNALGLlLIIAGGILGGLIFGFLERLLWPFGLHGAFIAIFWFLPIGG---------- 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  236 dmaYADLPEILQGTYHVGMYQAGFFpIMMFGLLGACVAFIQTSKPENRTKIFSIMVAAGFTSFLTGVTEPIEFAFMFVAP 315
Cdd:pfam02378 229 ---SNPIANQQAYGAGAAHILTGGF-DVMFGGPGATLALYAAAFLFKKSKVKKLLGSAALTPFLFGITEPLEFGFPFVLN 304
                         330
                  ....*....|.
gi 552909034  316 VLYLLHALLTG 326
Cdd:pfam02378 305 PPFFIPAILAG 315
PTS-IIBC-alpha TIGR02005
PTS system, alpha-glucoside-specific IIBC component; This model represents a family of fused ...
5-487 7.34e-48

PTS system, alpha-glucoside-specific IIBC component; This model represents a family of fused PTS enzyme II B and C domains. A gene from Clostridium has been partially characterized as a maltose transporter, while genes from Fusobacterium and Klebsiella have been proposed to transport the five non-standard isomers of sucrose. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273925 [Multi-domain]  Cd Length: 524  Bit Score: 172.69  E-value: 7.34e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034    5 LQKIGKALMVPVAVLPAAAIMLGIGYWI-DPTGWGANSQLAAFLIK-------AGAAIMDNMAILFAVGVAYGLSKDKDG 76
Cdd:TIGR02005   4 IQRFGGAMFVPVLLFAFAGIVVGFAILFkNPDIMGSLADQNTFWYKfwsvieeGGWTVFRQMPLIFVVGLPIGLAKKAQG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   77 AAALAGLVAF--------EIVTTLLSTGAVS----QIMGIPQEEVHAAFGKINNQFIG-ILCGVISGELYNKFHKIELPR 143
Cdd:TIGR02005  84 RACLAALMGYltfnyfinAILTQWGSSFGVNftqgVGVGVSGLTSIAGIKTLDTSIIGaIIISGIITYIHNRFFDKRLPV 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  144 FLAFFSGKRFVPIITSVVMIVVSFILTYIWPIIYGALVTFGTNIAKLGPVGAGIYGFFNRLLIPVGLHHAVNSVFWFNVA 223
Cdd:TIGR02005 164 FLGIFQGTTFVVTIAFFVMLPCAAITCLVWPKVQMGIGSLQAFLISSGYIGVWLYTFLERILIPTGLHHFIYGPFIFGPA 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  224 GIND-IGRFWGSPDMAYADLPEILQgtyhvGMYQAGFFPIM----MFGLLGACVAFIQTSKPENRTKIFSIMVAAGFTSF 298
Cdd:TIGR02005 244 VVNHgIQAYWAQHLNEFAKSTKPLK-----ELFPYGGFALHgnskVFGCLGIALAMYATAPPENRKKVAGLLIPATLTAV 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  299 LTGVTEPIEFAFMFVAPVLYLLHALLTGISLFLAASFNWMAgfSFSGGFIDFF----LSLKNPNANNPFMLIVLGLVFFV 374
Cdd:TIGR02005 319 VVGITEPLEFTFLFIAPYLFVVHAVLAASMATVMYAFGVVG--NMGGGLIDFIatnwLPLFKNHWGTYVTQIIIGLCFTA 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  375 VYYFVFLFVIKAFNLKTPGREESEEEKAEAIK----------VKTTNSEL----AETLVGLLGGADNIVEVDNCTTRLRL 440
Cdd:TIGR02005 397 IYFLVFRFLILKFNIPTPGREDTEEEVKLYSKadykakkgdsVESKRASSgndkAAYFLQALGGKENIKDVTNCATRLRI 476
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 552909034  441 KVKDSANIKESEI--KKLVPGVLKPSKeSVQVIIGPHVEFVATELKRIL 487
Cdd:TIGR02005 477 SVKDESKVLDDEVfkKAGAHGVVRSGK-AIQVIVGLSVPQVREAFEQLV 524
pts-Glc TIGR00852
PTS system, maltose and glucose-specific subfamily, IIC component; The PTS Glucose-Glucoside ...
51-333 2.49e-42

PTS system, maltose and glucose-specific subfamily, IIC component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Glc family includes permeases specific for glucose, N-acetylglucosamine and a large variety of a- and b-glucosides. However, not all b-glucoside PTS permeases are in this class, as the cellobiose (Cel) b-glucoside PTS permease is in the Lac family (TC #4.A.3). These permeases show limited sequence similarity with members of the Fru family (TC #4.A.2). Several of the E. coli PTS permeases in the Glc family lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). Most of these permeases have the B and C domains linked together in a single polypeptide chain, and a cysteyl residue in the IIB domain is phosphorylated by direct phosphoryl transfer from IIAglc(his~P). Those permeases which lack a IIA domain include the maltose (Mal), arbutin-salicin-cellobiose (ASC), trehalose (Tre), putative glucoside (Glv) and sucrose (Scr) permeases of E. coli . Most, but not all Scr permeases of other bacteria also lack a IIA domain. This model is specific for the IIC domain of the Glc family PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]


Pssm-ID: 273299  Cd Length: 289  Bit Score: 152.09  E-value: 2.49e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034   51 GAAIMDNMAILFAVGVAYGLSKDKDGAAALAGLVAFEIVTTLLSTGAVSQImGIPQEEVHAAfgKINNQFIGILCGVISG 130
Cdd:TIGR00852   1 GSAAFFFLPLLFAIGAAKGFGGNPYLGAALAGILVHPVLNNAMGVGAQAVG-NFFGFEIAKV--GYTGVVGPIIVGAIAL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  131 ELYNKFHKIELPRFLAFFSGKRFVPIITSVVMIVVSFILTYIWPIIyGALVTFGTNIAKLGPVGAGIYGFFNRLLIPVGL 210
Cdd:TIGR00852  78 ALHERFLDKKLPDVLGFFLGPRFVVIIAGFVAILLIGPLGRVWPPV-GISALLHWLYSAGGALGGAIFGFLYRLLVPTGL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  211 HHAVNSVFWFNVAGINDIGR---FWGSPDMAYADLPEILQGTYHVGMYQ---AGFFPIMMFGLLGACVAFIQTSKPENRT 284
Cdd:TIGR00852 157 HHIFYAIFIQLIAGGTVIGGgqvIPGDALANMAQGGAALAVFFTAGDAKfksIGLPAAFSAGLGITEPAMYGVALRERRP 236
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 552909034  285 KIFSIMVAAGFTSFLTGVTEPIEFAFMFVAPVLYLLHALLTGISLFLAA 333
Cdd:TIGR00852 237 FVAGLIGSALLTAFLTGITEPLEFLFLFGAPGLYSIHAVLAGSIFTVAI 285
PtsG2 COG1264
Phosphotransferase system IIB components [Carbohydrate transport and metabolism];
412-487 8.16e-26

Phosphotransferase system IIB components [Carbohydrate transport and metabolism];


Pssm-ID: 440876 [Multi-domain]  Cd Length: 76  Bit Score: 100.19  E-value: 8.16e-26
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 552909034 412 SELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL-VPGVLKPSKEsVQVIIGPHVEFVATELKRIL 487
Cdd:COG1264    1 KELAKDILEALGGKENIVSVDHCATRLRVTVKDPSKVDEAALKKLgVKGVVKNGGQ-VQVIIGPGVDKVADEIEKLL 76
PTS_IIB_glc cd00212
PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: ...
412-487 7.35e-20

PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation


Pssm-ID: 238130 [Multi-domain]  Cd Length: 78  Bit Score: 83.74  E-value: 7.35e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 552909034 412 SELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL--VPGVLKpSKESVQVIIGPHV-EFVATELKRIL 487
Cdd:cd00212    1 EQLAKDILEALGGKENIVSLDHCATRLRLTVKDESKVDEAALKKLggVKGVVK-NGGQYQVIIGPGVaDVYKEAIKLLG 78
EIIB_glc TIGR00826
PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) ...
385-473 6.87e-12

PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Glc family includes permeases specific for glucose, N-acetylglucosamine and a large variety of a- and b-glucosides. However, not all b-glucoside PTS permeases are in this class, as the cellobiose (Cel) b-glucoside PTS permease is in the Lac family (TC #4.A.3). These permeases show limited sequence similarity with members of the Fru family (TC #4.A.2). Several of the E. coli PTS permeases in the Glc family lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). Most of these permeases have the B and C domains linked together in a single polypeptide chain, and a cysteyl residue in the IIB domain is phosphorylated by direct phosphoryl transfer from IIAglc(his~P). Those permeases which lack a IIA domain include the maltose (Mal), arbutin-salicin-cellobiose (ASC), trehalose (Tre), putative glucoside (Glv) and sucrose (Scr) permeases of E. coli . Most, but not all Scr permeases of other bacteria also lack a IIA domain. This model is specific for the IIB domain of the Glc family PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]


Pssm-ID: 273288 [Multi-domain]  Cd Length: 88  Bit Score: 61.22  E-value: 6.87e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034  385 KAFNLKTPGREESEEEKAEAIKVKTTNsELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKLVPGVLKPS 464
Cdd:TIGR00826   1 TRLRLKTPGREKADEEAIAAGEGVKGV-FTAAGQIQALGGTGNVNKVDACITRLRVGVADVSKVDDAVLKKLGAHGVNPL 79

                  ....*....
gi 552909034  465 KESVQVIIG 473
Cdd:TIGR00826  80 QRAVQVISG 88
PTS_EIIB pfam00367
phosphotransferase system, EIIB;
416-446 5.26e-10

phosphotransferase system, EIIB;


Pssm-ID: 459785 [Multi-domain]  Cd Length: 32  Bit Score: 54.30  E-value: 5.26e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 552909034  416 ETLVGLLGGADNIVEVDNCTTRLRLKVKDSA 446
Cdd:pfam00367   1 KEILEALGGKENIKSVDHCATRLRLTVKDES 31
murP PRK09586
PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed
408-474 1.00e-07

PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed


Pssm-ID: 181971 [Multi-domain]  Cd Length: 476  Bit Score: 54.30  E-value: 1.00e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 552909034 408 KTTNSELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKLvPGVLK--PSKESVQVIIGP 474
Cdd:PRK09586   2 AKISSELLNTILTRVGGPGNIASCGNCMTRLRLTLHDSSLVDPAAIKTI-EGVKGviLSDDQVQVVLGP 69
PRK09702 PRK09702
PTS sugar transporter subunit IIB;
384-487 5.24e-07

PTS sugar transporter subunit IIB;


Pssm-ID: 77355 [Multi-domain]  Cd Length: 161  Bit Score: 49.32  E-value: 5.24e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 384 IKAFNLKTPGREESEEEKAEAIKVKTTNSEL-----------AETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESE 452
Cdd:PRK09702  31 ILQFNMCTPGREDAEVKLYSKAEYKASRGQTtaaepkkeldqAAGILQALGGVGNISSINNCATRLRIALHDMSQTLDDE 110
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 552909034 453 I-KKL-VPGVLKpSKESVQVIIGPHVEFVATELKRIL 487
Cdd:PRK09702 111 VfKKLgAHGVFR-SGDAIQVIIGLHVSQLREQLDSLI 146
PRK09796 PRK09796
PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional
412-488 7.17e-07

PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional


Pssm-ID: 182081  Cd Length: 472  Bit Score: 51.72  E-value: 7.17e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 552909034 412 SELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL--VPGVLKpSKESVQVIIGPHVEFVATELKRILG 488
Cdd:PRK09796   6 AALARSVIAALGGVDNISAVTHCMTRLRFVIKDDALIDSPTLKTIpgVLGVVR-SDNQCQVIIGNTVSQAFQEVVSLLP 83
PRK14905 PRK14905
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; ...
412-487 5.06e-06

triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; Provisional


Pssm-ID: 184898 [Multi-domain]  Cd Length: 355  Bit Score: 48.49  E-value: 5.06e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 552909034 412 SELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL--VPGVLKPSKEsVQVIIGPH-VEFVATELKRIL 487
Cdd:PRK14905 275 SEIAIQLIDHLGGKDNISALTHCASRIRVMLRNDGHIDKSAIEKIdcVKGLFSIANQ-YQIILGAGiVEKIHEEMKALL 352
PRK11007 PRK11007
PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional
411-489 8.04e-06

PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional


Pssm-ID: 182896  Cd Length: 473  Bit Score: 48.14  E-value: 8.04e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 411 NSELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANIKESEIKKL--VPGVLKPSKEsVQVIIGPHVEFVATELKRILG 488
Cdd:PRK11007   6 NQQDIDRLIELVGGRENIATVSHCITRLRFVLNDPANADPKEIEQLpmVKGCFTNAGQ-FQVVIGTEVGDYYKALIATTG 84

                 .
gi 552909034 489 K 489
Cdd:PRK11007  85 Q 85
PRK09824 PRK09824
PTS system beta-glucoside-specific transporter subunits IIABC; Provisional
413-488 8.32e-06

PTS system beta-glucoside-specific transporter subunits IIABC; Provisional


Pssm-ID: 236627 [Multi-domain]  Cd Length: 627  Bit Score: 48.17  E-value: 8.32e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 552909034 413 ELAETLVGLLGGADNIVEVDNCTTRLRLKVKDSANiKESEIKKLVPGVLK--PSKESVQVIIGPHVEFVATELKRILG 488
Cdd:PRK09824   5 ELAREIVAGVGGADNIVSLMHCATRLRFKLKDNSK-AQAEVLKKNPGVIMvvESGGQFQVVIGNHVADVFLAVNSVAG 81
PRK11007 PRK11007
PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional
144-332 1.01e-04

PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional


Pssm-ID: 182896  Cd Length: 473  Bit Score: 44.68  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 144 FLAFFSG--KRFVP-----IITSVVMIVVSFIL--TYIWPI--IYGALVTFGTNIAKLG---PVGAGIYGFFNRLLIPVG 209
Cdd:PRK11007 241 ALGFIETrlKRIVPdylylVVVPVCSLILAVFLahALIGPFgrMIGDGVAFAVKALMTGsfaPIGAALFGFLYAPLVITG 320
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 552909034 210 LHHAVNSVfwfNVAGINDIGrfwGSPDMAYADLPEILQGTyhvgmyqagffpimmfgllgACVAFIQTSKPENRTKifsI 289
Cdd:PRK11007 321 VHQTTLAI---DLQMIQSMG---GTPVWPLIALSNIAQAS--------------------AVVGIIIISRKHNERE---I 371
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 552909034 290 MVAAGFTSFLtGVTEP------IEFAF-MFVAPVLYLLHALLTGISLFLA 332
Cdd:PRK11007 372 SVPAAISAYL-GVTEPamyginLKYRFpMLCAMIGSALAGLICGLNGVMA 420
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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