NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|550045018|ref|WP_022580591|]
View 

FAD-dependent oxidoreductase [Pseudomonas aeruginosa]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Phn_aa_oxid super family cl26295
putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 ...
 5-452 0e+00

putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.


The actual alignment was detected with superfamily member TIGR03329:

Pssm-ID: 274522 [Multi-domain]  Cd Length: 460  Bit Score: 830.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018    5 PFWLDQALRSEHAAPCPPLAGDTRADLCIVGGGYTGLWTAIMLKEHDPGLDVVLVEADLCGAGASGRNGGCALSWSAKFF 84
Cdd:TIGR03329   1 PFWLEQALALEQPDPAPPLVGDTQADVCIVGGGFTGLWTAIMIKQQRPALDVLVLEADLCGAGASGRNGGCMLTWSTKFF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018   85 TLERLFGLTEAIRLVKASEDSIRAIGAFCQRYDVEADYRLDGTLYTATNPAQVGSTDSVIAALERHGINSFVKRPLADVQ 164
Cdd:TIGR03329  81 TLKRLFGEAEAARLVKASEQAVLEIAAFCEQHNIDAQLRLDGTLYTATNPAQVGSMDPVVDALERRGINSWQRLSEGELA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  165 RLAGSRRHLEGWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRVVADRVVLALNAWMARA 244
Cdd:TIGR03329 161 RRTGSARHLEGFYSPVAASVQPGLLVRGLRRVALELGVEIHENTPMTGLEEGQPAVVRTPDGQVTADKVVLALNAWMASH 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  245 FPQFERSVAIVSSDMLITEPRPDLLQEIGLTSGVSVLDSRIFVHYYHNTPDGRLMLGKGGNTFAYGGRMLPVFDRPSPYL 324
Cdd:TIGR03329 241 FPQFERSIAIVSSDMVITEPAPDLLAATGLDHGTSVLDSRIFVHYYRSTPDGRLMLGKGGNTFAYGGRMLPVFNQPSPYE 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  325 GQLRGSLREFFPEFAEVAIEASWNGPSDRSVTGLPFFGRLDGRDNVFYGFGYSGSGVGPCHMGGQILSSLALGLDNPWTR 404
Cdd:TIGR03329 321 ALLTRSLRKFFPALAEVPIAASWNGPSDRSVTGLPFFGRLNGQPNVFYGFGYSGNGVAPSRMGGQILSSLVLGLDNPWTR 400

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 550045018  405 SPLTQGPLGRFPPEPIRYVGSLMVRNAIRRKEHAEDVGRRPRHLDVRL 452
Cdd:TIGR03329 401 SPLVKGPLGYFPPEPIRYLGALVVRNAIRRKERAEDEGRRPFLLDKWL 448
 
Name Accession Description Interval E-value
Phn_aa_oxid TIGR03329
putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 ...
 5-452 0e+00

putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.


Pssm-ID: 274522 [Multi-domain]  Cd Length: 460  Bit Score: 830.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018    5 PFWLDQALRSEHAAPCPPLAGDTRADLCIVGGGYTGLWTAIMLKEHDPGLDVVLVEADLCGAGASGRNGGCALSWSAKFF 84
Cdd:TIGR03329   1 PFWLEQALALEQPDPAPPLVGDTQADVCIVGGGFTGLWTAIMIKQQRPALDVLVLEADLCGAGASGRNGGCMLTWSTKFF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018   85 TLERLFGLTEAIRLVKASEDSIRAIGAFCQRYDVEADYRLDGTLYTATNPAQVGSTDSVIAALERHGINSFVKRPLADVQ 164
Cdd:TIGR03329  81 TLKRLFGEAEAARLVKASEQAVLEIAAFCEQHNIDAQLRLDGTLYTATNPAQVGSMDPVVDALERRGINSWQRLSEGELA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  165 RLAGSRRHLEGWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRVVADRVVLALNAWMARA 244
Cdd:TIGR03329 161 RRTGSARHLEGFYSPVAASVQPGLLVRGLRRVALELGVEIHENTPMTGLEEGQPAVVRTPDGQVTADKVVLALNAWMASH 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  245 FPQFERSVAIVSSDMLITEPRPDLLQEIGLTSGVSVLDSRIFVHYYHNTPDGRLMLGKGGNTFAYGGRMLPVFDRPSPYL 324
Cdd:TIGR03329 241 FPQFERSIAIVSSDMVITEPAPDLLAATGLDHGTSVLDSRIFVHYYRSTPDGRLMLGKGGNTFAYGGRMLPVFNQPSPYE 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  325 GQLRGSLREFFPEFAEVAIEASWNGPSDRSVTGLPFFGRLDGRDNVFYGFGYSGSGVGPCHMGGQILSSLALGLDNPWTR 404
Cdd:TIGR03329 321 ALLTRSLRKFFPALAEVPIAASWNGPSDRSVTGLPFFGRLNGQPNVFYGFGYSGNGVAPSRMGGQILSSLVLGLDNPWTR 400

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 550045018  405 SPLTQGPLGRFPPEPIRYVGSLMVRNAIRRKEHAEDVGRRPRHLDVRL 452
Cdd:TIGR03329 401 SPLVKGPLGYFPPEPIRYLGALVVRNAIRRKERAEDEGRRPFLLDKWL 448
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
27-407 6.56e-74

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 236.73  E-value: 6.56e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  27 TRADLCIVGGGYTGLWTAIMLKEHdpGLDVVLVEADLCGAGASGRNGGCalswsakfftLERLFGLTEAIRLVKASEDSI 106
Cdd:COG0665    1 ATADVVVIGGGIAGLSTAYHLARR--GLDVTVLERGRPGSGASGRNAGQ----------LRPGLAALADRALVRLAREAL 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 107 RAIGAFCQRYDVEADYRLDGTLYTATNPAQVGSTDSVIAALERHGINSFV--KRPLADVQRLAGSRRHLEGWFSPAAATV 184
Cdd:COG0665   69 DLWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELldAAELREREPGLGSPDYAGGLYDPDDGHV 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 185 QPGKLVRGLRRVALQLGVRLYEGTPMRGLEH--GRPAEVVTPHGRVVADRVVLALNAWMARAFPQFERSVAI--VSSDML 260
Cdd:COG0665  149 DPAKLVRALARAARAAGVRIREGTPVTGLERegGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLrpVRGYVL 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 261 ITEPRPDLLQEIGLTsgvsvlDSRifvHYYHNTPDGRLMLGkggntfayGGRMLPVFDRPSP--YLGQLRGSLREFFPEF 338
Cdd:COG0665  229 VTEPLPDLPLRPVLD------DTG---VYLRPTADGRLLVG--------GTAEPAGFDRAPTpeRLEALLRRLRRLFPAL 291

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550045018 339 AEVAIEASWNGPSDRSVTGLPFFGRLDGRDNVFYGFGYSGSGVGPCHMGGQILSSLALGLDNPWTRSPL 407
Cdd:COG0665  292 ADAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPF 360
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 30-394 6.70e-53

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 181.06  E-value: 6.70e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018   30 DLCIVGGGYTGLWTAIMLKEHdpGLDVVLVEAD-LCGAGASGRNGGCALSWsakfftlerlFGLTEAIRLVKASEDSIRA 108
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARR--GLSVTLLERGdDPGSGASGRNAGLIHPG----------LRYLEPSELARLALEALDL 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  109 IGAFCQRYDVEADYRLDGTLYTATNPAQvGSTDSVIAALERHGINSFVKRPLADVQRLAGSRRHLEGWFSPAAATVQPGK 188
Cdd:pfam01266  69 WEELEEELGIDCGFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEPLLPGLRGGLFYPDGGHVDPAR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  189 LVRGLRRVALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRvvADRVVLALNAWMAR-AFPQFERSVAIVSSDMLITEPRPD 267
Cdd:pfam01266 148 LLRALARAAEALGVRIIEGTEVTGIEEEGGVWGVVTTGE--ADAVVNAAGAWADLlALPGLRLPVRPVRGQVLVLEPLPE 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  268 LLqeigLTSGVSVLDSRIFVHYYHNTPDGRLMLGKggnTFAYGGRMLPVFDRPSpyLGQLRGSLREFFPEFAEvaIEASW 347
Cdd:pfam01266 226 AL----LILPVPITVDPGRGVYLRPRADGRLLLGG---TDEEDGFDDPTPDPEE--IEELLEAARRLFPALAD--IERAW 294

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 550045018  348 NGPSDrSVTGLPFFGRLDGRdNVFYGFGYSGSGVGPCHMGGQILSSL 394
Cdd:pfam01266 295 AGLRP-LPDGLPIIGRPGSP-GLYLATGHGGHGLTLAPGIGKLLAEL 339
solA PRK11259
N-methyl-L-tryptophan oxidase;
175-255 2.68e-06

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 49.45  E-value: 2.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 175 GWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEHGRPA-EVVTPHGRVVADRVVLALNAWMARAFPQFERSVA 253
Cdd:PRK11259 137 ALFEPDGGFLRPELAIKAHLRLAREAGAELLFNEPVTAIEADGDGvTVTTADGTYEAKKLVVSAGAWVKDLLPPLELPLT 216


                 ..
gi 550045018 254 IV 255
Cdd:PRK11259 217 PV 218
 
Name Accession Description Interval E-value
Phn_aa_oxid TIGR03329
putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 ...
 5-452 0e+00

putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.


Pssm-ID: 274522 [Multi-domain]  Cd Length: 460  Bit Score: 830.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018    5 PFWLDQALRSEHAAPCPPLAGDTRADLCIVGGGYTGLWTAIMLKEHDPGLDVVLVEADLCGAGASGRNGGCALSWSAKFF 84
Cdd:TIGR03329   1 PFWLEQALALEQPDPAPPLVGDTQADVCIVGGGFTGLWTAIMIKQQRPALDVLVLEADLCGAGASGRNGGCMLTWSTKFF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018   85 TLERLFGLTEAIRLVKASEDSIRAIGAFCQRYDVEADYRLDGTLYTATNPAQVGSTDSVIAALERHGINSFVKRPLADVQ 164
Cdd:TIGR03329  81 TLKRLFGEAEAARLVKASEQAVLEIAAFCEQHNIDAQLRLDGTLYTATNPAQVGSMDPVVDALERRGINSWQRLSEGELA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  165 RLAGSRRHLEGWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRVVADRVVLALNAWMARA 244
Cdd:TIGR03329 161 RRTGSARHLEGFYSPVAASVQPGLLVRGLRRVALELGVEIHENTPMTGLEEGQPAVVRTPDGQVTADKVVLALNAWMASH 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  245 FPQFERSVAIVSSDMLITEPRPDLLQEIGLTSGVSVLDSRIFVHYYHNTPDGRLMLGKGGNTFAYGGRMLPVFDRPSPYL 324
Cdd:TIGR03329 241 FPQFERSIAIVSSDMVITEPAPDLLAATGLDHGTSVLDSRIFVHYYRSTPDGRLMLGKGGNTFAYGGRMLPVFNQPSPYE 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  325 GQLRGSLREFFPEFAEVAIEASWNGPSDRSVTGLPFFGRLDGRDNVFYGFGYSGSGVGPCHMGGQILSSLALGLDNPWTR 404
Cdd:TIGR03329 321 ALLTRSLRKFFPALAEVPIAASWNGPSDRSVTGLPFFGRLNGQPNVFYGFGYSGNGVAPSRMGGQILSSLVLGLDNPWTR 400

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 550045018  405 SPLTQGPLGRFPPEPIRYVGSLMVRNAIRRKEHAEDVGRRPRHLDVRL 452
Cdd:TIGR03329 401 SPLVKGPLGYFPPEPIRYLGALVVRNAIRRKERAEDEGRRPFLLDKWL 448
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
27-407 6.56e-74

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 236.73  E-value: 6.56e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  27 TRADLCIVGGGYTGLWTAIMLKEHdpGLDVVLVEADLCGAGASGRNGGCalswsakfftLERLFGLTEAIRLVKASEDSI 106
Cdd:COG0665    1 ATADVVVIGGGIAGLSTAYHLARR--GLDVTVLERGRPGSGASGRNAGQ----------LRPGLAALADRALVRLAREAL 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 107 RAIGAFCQRYDVEADYRLDGTLYTATNPAQVGSTDSVIAALERHGINSFV--KRPLADVQRLAGSRRHLEGWFSPAAATV 184
Cdd:COG0665   69 DLWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELldAAELREREPGLGSPDYAGGLYDPDDGHV 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 185 QPGKLVRGLRRVALQLGVRLYEGTPMRGLEH--GRPAEVVTPHGRVVADRVVLALNAWMARAFPQFERSVAI--VSSDML 260
Cdd:COG0665  149 DPAKLVRALARAARAAGVRIREGTPVTGLERegGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLrpVRGYVL 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 261 ITEPRPDLLQEIGLTsgvsvlDSRifvHYYHNTPDGRLMLGkggntfayGGRMLPVFDRPSP--YLGQLRGSLREFFPEF 338
Cdd:COG0665  229 VTEPLPDLPLRPVLD------DTG---VYLRPTADGRLLVG--------GTAEPAGFDRAPTpeRLEALLRRLRRLFPAL 291

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 550045018 339 AEVAIEASWNGPSDRSVTGLPFFGRLDGRDNVFYGFGYSGSGVGPCHMGGQILSSLALGLDNPWTRSPL 407
Cdd:COG0665  292 ADAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPF 360
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 30-394 6.70e-53

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 181.06  E-value: 6.70e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018   30 DLCIVGGGYTGLWTAIMLKEHdpGLDVVLVEAD-LCGAGASGRNGGCALSWsakfftlerlFGLTEAIRLVKASEDSIRA 108
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARR--GLSVTLLERGdDPGSGASGRNAGLIHPG----------LRYLEPSELARLALEALDL 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  109 IGAFCQRYDVEADYRLDGTLYTATNPAQvGSTDSVIAALERHGINSFVKRPLADVQRLAGSRRHLEGWFSPAAATVQPGK 188
Cdd:pfam01266  69 WEELEEELGIDCGFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEPLLPGLRGGLFYPDGGHVDPAR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  189 LVRGLRRVALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRvvADRVVLALNAWMAR-AFPQFERSVAIVSSDMLITEPRPD 267
Cdd:pfam01266 148 LLRALARAAEALGVRIIEGTEVTGIEEEGGVWGVVTTGE--ADAVVNAAGAWADLlALPGLRLPVRPVRGQVLVLEPLPE 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  268 LLqeigLTSGVSVLDSRIFVHYYHNTPDGRLMLGKggnTFAYGGRMLPVFDRPSpyLGQLRGSLREFFPEFAEvaIEASW 347
Cdd:pfam01266 226 AL----LILPVPITVDPGRGVYLRPRADGRLLLGG---TDEEDGFDDPTPDPEE--IEELLEAARRLFPALAD--IERAW 294

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 550045018  348 NGPSDrSVTGLPFFGRLDGRdNVFYGFGYSGSGVGPCHMGGQILSSL 394
Cdd:pfam01266 295 AGLRP-LPDGLPIIGRPGSP-GLYLATGHGGHGLTLAPGIGKLLAEL 339
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 26-236 2.65e-07

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 52.53  E-value: 2.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  26 DTRADLCIVGGGYTGLWTAIMLKEHdpGLDVVLVEADLCGAGASGRNGG---CALSWSAKfftlerlfglteairlvKAS 102
Cdd:COG1053    1 DHEYDVVVVGSGGAGLRAALEAAEA--GLKVLVLEKVPPRGGHTAAAQGginAAGTNVQK-----------------AAG 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 103 EDSIRAIgafcqrydveADYRLDGTLYTAtNPAQV-----GSTDsVIAALERHGINsFVKRPLADVQRLAG---SRRHle 174
Cdd:COG1053   62 EDSPEEH----------FYDTVKGGDGLA-DQDLVealaeEAPE-AIDWLEAQGVP-FSRTPDGRLPQFGGhsvGRTC-- 126

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 175 gwfspaAATVQPGK-LVRGLRRVALQLGVRLYEGTPMRGL--EHGRP--AEVVTPHGRVV---ADRVVLA 236
Cdd:COG1053  127 ------YAGDGTGHaLLATLYQAALRLGVEIFTETEVLDLivDDGRVvgVVARDRTGEIVrirAKAVVLA 190
solA PRK11259
N-methyl-L-tryptophan oxidase;
175-255 2.68e-06

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 49.45  E-value: 2.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 175 GWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEHGRPA-EVVTPHGRVVADRVVLALNAWMARAFPQFERSVA 253
Cdd:PRK11259 137 ALFEPDGGFLRPELAIKAHLRLAREAGAELLFNEPVTAIEADGDGvTVTTADGTYEAKKLVVSAGAWVKDLLPPLELPLT 216


                 ..
gi 550045018 254 IV 255
Cdd:PRK11259 217 PV 218
PRK00711 PRK00711
D-amino acid dehydrogenase;
97-240 7.67e-06

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 47.87  E-value: 7.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  97 RLVKASEDSIRAIGAFCQRYDVEADYRLDGTLYTATNPAQVGSTDSVIAALERHGinsfVKRPLADVQRLAGsrrhlegw 176
Cdd:PRK00711 107 RMVRLAEYSRDCLKALRAETGIQYEGRQGGTLQLFRTQQQLDAAAKDIAVLEEAG----VPYELLDRDELAA-------- 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 177 FSPAAATVQpGKLVRGLR-----------------RVALQLGVRLYEGTPMRGLEH--GRPAEVVTPHGRVVADRVVLAL 237
Cdd:PRK00711 175 VEPALAGVR-HKLVGGLRlpndetgdcqlftqrlaAMAEQLGVKFRFNTPVDGLLVegGRITGVQTGGGVITADAYVVAL 253


                 ...
gi 550045018 238 NAW 240
Cdd:PRK00711 254 GSY 256
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 33-249 6.47e-04

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 42.14  E-value: 6.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018  33 IVGGGYTGLWTAIMLKEHdpGLDVVLVEADLCGA-GASG-RNGgcALS--WSAKFFTLERLF--GLTEAIRLVKASEDSI 106
Cdd:PRK01747 265 IIGGGIAGAALALALARR--GWQVTLYEADEAPAqGASGnRQG--ALYplLSKDDNALSRFFraAFLFARRFYDALPAAG 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550045018 107 RAIGA-FCqrydveadyrldGTLYTATNPAQVGSTDSVIAALERHGINSFVKRplADVQRLAGSRRHLEGWFSPAAATVQ 185
Cdd:PRK01747 341 VAFDHdWC------------GVLQLAWDEKSAEKIAKMLALGLPAELARALDA--EEAEELAGLPVPCGGIFYPQGGWLC 406

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550045018 186 PGKLVRGLRRvALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRVVADR--VVLAlNAWMARAFPQFE 249
Cdd:PRK01747 407 PAELCRALLA-LAGQQLTIHFGHEVARLEREDDGWQLDFAGGTLASApvVVLA-NGHDAARFAQTA 470
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
28-61 4.47e-03

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 39.19  E-value: 4.47e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 550045018  28 RADLCIVGGGYTGLWTAIMLKEHDPGLDVVLVEA 61
Cdd:PRK07333   1 QCDVVIAGGGYVGLALAVALKQAAPHLPVTVVDA 34
glpA PRK11101
anaerobic glycerol-3-phosphate dehydrogenase subunit A;
30-74 5.99e-03

anaerobic glycerol-3-phosphate dehydrogenase subunit A;


Pssm-ID: 236847 [Multi-domain]  Cd Length: 546  Bit Score: 38.84  E-value: 5.99e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 550045018  30 DLCIVGGGYTGlwTAIMLKEHDPGLDVVLVEADLCGAGASGRNGG 74
Cdd:PRK11101   8 DVIIIGGGATG--AGIARDCALRGLRCILVERHDIATGATGRNHG 50
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
33-84 7.05e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 35.20  E-value: 7.05e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 550045018   33 IVGGGYTGLWTAIMLKEHdpGLDVVLVEA--DLCGAGASGRNGGCALSWSAKFF 84
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKR--GFRVLVLEKrdRLGGNAYSYRVPGYVFDYGAHIF 52
PRK06854 PRK06854
adenylyl-sulfate reductase subunit alpha;
30-72 7.28e-03

adenylyl-sulfate reductase subunit alpha;


Pssm-ID: 235879 [Multi-domain]  Cd Length: 608  Bit Score: 38.75  E-value: 7.28e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 550045018  30 DLCIVGGGYTGLWTAIMLKEHDPGLDVVLVE---ADLCGAGASGRN 72
Cdd:PRK06854  13 DILIIGGGMAGCGAAFEAKEWAPDLKVLIVEkanIKRSGAVAQGLS 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH