|
Name |
Accession |
Description |
Interval |
E-value |
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
47-342 |
2.71e-133 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 381.16 E-value: 2.71e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 47 TLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTS 126
Cdd:cd01557 1 SLHPATHALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADWVPYGGGAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 127 LYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSvTPVSLLADPaFIRAWVGGVGNYKLGGNYGPTVLVQQEALK 206
Cdd:cd01557 81 LYIRPFIFGTDPQLGVSPALEYLFAVFASPVGAYFKGGE-KGVSALVSS-FRRAAPGGPGAAKAGGNYAASLLAQKEAAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 207 RGCEQVLWLYGPDHQLTEVGTMNIFVYWtheDGvlELVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRA 286
Cdd:cd01557 159 KGYDQALWLDGAHGYVAEVGTMNIFFVK---DG--ELITPPLDGSILPGITRDSILELARDLG-IKVEERPITRDELYEA 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 547235678 287 LeegrvrEVFGSGTACQVCPVHRILYKDRNlhiPTMENGPELILRFQKELKEIQYG 342
Cdd:cd01557 233 D------EVFATGTAAVVTPVGEIDYRGKE---PGEGEVGPVTKKLYDLLTDIQYG 279
|
|
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
1-352 |
3.97e-125 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 363.31 E-value: 3.97e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 1 MTQKPHKKPGPGEP-------LVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQ 73
Cdd:PRK13357 1 FTVTLKPNPTSDEKraidwanLGFGYVFTDHMVVIDYKDGKWHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 74 QVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAA-GTSLYVRPVLIGNEPSLGVSQPTRALLFV 152
Cdd:PRK13357 81 SIVLFRPDANAKRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVPPYGeGASLYLRPFMIATEPFLGVKPAEEYIFCV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 153 ILCPVGAYFPGGsVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQ-LTEVGTMNIF 231
Cdd:PRK13357 161 IASPVGAYFKGG-VKPVSIWVSDEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTyIEEVGGMNFF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 232 -VYwthEDGVlelVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRI 310
Cdd:PRK13357 240 fIT---KDGT---VTPPLSGSILPGITRDSLLQLAEDLG-LTVEERPVSIDEWQADAASGEFTEAFACGTAAVITPIGGI 312
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 547235678 311 LYKDRNLHIPTMENGPeLILRFQKELKEIQYGIRA--HEWMFPV 352
Cdd:PRK13357 313 KYKDKEFVIGDGEVGP-VTQKLYDELTGIQFGDVEdpHGWIVKV 355
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
35-352 |
9.12e-92 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 277.02 E-value: 9.12e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 35 WGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEV 114
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 115 DKDWVPDA-AGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGsVTPVSLLADPAFIRAWVGGVGNYKLGGN 193
Cdd:TIGR01123 81 NKDWVPPYgSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKGG-LAPVSIFVTTEYDRAAPGGTGAVKVGGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 194 YGPTVLVQQEALKRGCEQVLWLYGPDHQ-LTEVGTMNIFVYWTheDGvlELVTPPLNGVILPGVVRQSLLDMAQTWGeFR 272
Cdd:TIGR01123 160 YAASLLAQAKAAEQGCDQVVYLDPVEHTyIEEVGAMNFFFITG--DG--ELVTPPLSGSILPGITRDSLLQLAKDLG-ME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 273 VVERTITMKQLLRALEEGrvREVFGSGTACQVCPVHRILYKDRNLHIPTMENGpELILRFQKELKEIQYGIRA--HEWMF 350
Cdd:TIGR01123 235 VEERRIDIDELKAFVEAG--EIVFACGTAAVITPVGEIQHGGKEVVFASGQPG-EVTKALYDELTDIQYGDFEdpYGWIV 311
|
..
gi 547235678 351 PV 352
Cdd:TIGR01123 312 EV 313
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
35-342 |
5.34e-70 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 220.06 E-value: 5.34e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 35 WGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGkdqqvRLFRPWLNMDRMLRSAMRLCLP-SFDKLELLECIRRLIE 113
Cdd:COG0115 4 WLNGELVPEEEATISVLDRGLHYGDGVFEGIRAYDG-----RLFRLDEHLARLNRSAKRLGIPiPYTEEELLEAIRELVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 114 VDKDwvpdaagTSLYVRPVLIGNEPSLGVSQPT-RALLFVILCPVGAYFPGGSVTPVSLLADPaFIRAWVGGVGNYKlGG 192
Cdd:COG0115 79 ANGL-------EDGYIRPQVTRGVGGRGVFAEEyEPTVIIIASPLPAYPAEAYEKGVRVITSP-YRRAAPGGLGGIK-TG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 193 NYGPTVLVQQEALKRGCEQVLWLyGPDHQLTEVGTMNIFVYwthEDGVLelVTPPLNGVILPGVVRQSLLDMAQTWGeFR 272
Cdd:COG0115 150 NYLNNVLAKQEAKEAGADEALLL-DTDGYVAEGSGSNVFIV---KDGVL--VTPPLSGGILPGITRDSVIELARELG-IP 222
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 273 VVERTITMKQLLRAleegrvREVFGSGTACQVCPVHRIlykdRNLHIPTMENGPeLILRFQKELKEIQYG 342
Cdd:COG0115 223 VEERPISLEELYTA------DEVFLTGTAAEVTPVTEI----DGRPIGDGKPGP-VTRRLRELYTDIVRG 281
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
60-310 |
3.02e-32 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 120.15 E-value: 3.02e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 60 QLFEGMKAFKGkdqqvRLFRPWLNMDRMLRSAMRLCLP-SFDKLELLECIRRLIEVDKDWVPdaagtslYVRPVLIGNEP 138
Cdd:pfam01063 1 GVFETLRVYNG-----KIFFLDEHLARLRRSAKLLGIPlPFDEEDLRKIIEELLKANGLGVG-------RLRLTVSRGPG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 139 SLGVSQPT-RALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAwvggvgNYKlGGNYGPTVLVQQEALKRGCEQVLwLYG 217
Cdd:pfam01063 69 GFGLPTSDpTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLP------GAK-TLNYLENVLARREAKAQGADDAL-LLD 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 218 PDHQLTEVGTMNIFvyWTHEDgvlELVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRAleegrvREVFG 297
Cdd:pfam01063 141 EDGNVTEGSTSNVF--LVKGG---TLYTPPLESGILPGITRQALLDLAKALG-LEVEERPITLADLQEA------DEAFL 208
|
250
....*....|...
gi 547235678 298 SGTACQVCPVHRI 310
Cdd:pfam01063 209 TNSLRGVTPVSSI 221
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
47-342 |
2.71e-133 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 381.16 E-value: 2.71e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 47 TLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTS 126
Cdd:cd01557 1 SLHPATHALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADWVPYGGGAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 127 LYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSvTPVSLLADPaFIRAWVGGVGNYKLGGNYGPTVLVQQEALK 206
Cdd:cd01557 81 LYIRPFIFGTDPQLGVSPALEYLFAVFASPVGAYFKGGE-KGVSALVSS-FRRAAPGGPGAAKAGGNYAASLLAQKEAAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 207 RGCEQVLWLYGPDHQLTEVGTMNIFVYWtheDGvlELVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRA 286
Cdd:cd01557 159 KGYDQALWLDGAHGYVAEVGTMNIFFVK---DG--ELITPPLDGSILPGITRDSILELARDLG-IKVEERPITRDELYEA 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 547235678 287 LeegrvrEVFGSGTACQVCPVHRILYKDRNlhiPTMENGPELILRFQKELKEIQYG 342
Cdd:cd01557 233 D------EVFATGTAAVVTPVGEIDYRGKE---PGEGEVGPVTKKLYDLLTDIQYG 279
|
|
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
1-352 |
3.97e-125 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 363.31 E-value: 3.97e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 1 MTQKPHKKPGPGEP-------LVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQ 73
Cdd:PRK13357 1 FTVTLKPNPTSDEKraidwanLGFGYVFTDHMVVIDYKDGKWHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 74 QVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAA-GTSLYVRPVLIGNEPSLGVSQPTRALLFV 152
Cdd:PRK13357 81 SIVLFRPDANAKRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVPPYGeGASLYLRPFMIATEPFLGVKPAEEYIFCV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 153 ILCPVGAYFPGGsVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQ-LTEVGTMNIF 231
Cdd:PRK13357 161 IASPVGAYFKGG-VKPVSIWVSDEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTyIEEVGGMNFF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 232 -VYwthEDGVlelVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRI 310
Cdd:PRK13357 240 fIT---KDGT---VTPPLSGSILPGITRDSLLQLAEDLG-LTVEERPVSIDEWQADAASGEFTEAFACGTAAVITPIGGI 312
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 547235678 311 LYKDRNLHIPTMENGPeLILRFQKELKEIQYGIRA--HEWMFPV 352
Cdd:PRK13357 313 KYKDKEFVIGDGEVGP-VTQKLYDELTGIQFGDVEdpHGWIVKV 355
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
35-352 |
9.12e-92 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 277.02 E-value: 9.12e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 35 WGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEV 114
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 115 DKDWVPDA-AGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGsVTPVSLLADPAFIRAWVGGVGNYKLGGN 193
Cdd:TIGR01123 81 NKDWVPPYgSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKGG-LAPVSIFVTTEYDRAAPGGTGAVKVGGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 194 YGPTVLVQQEALKRGCEQVLWLYGPDHQ-LTEVGTMNIFVYWTheDGvlELVTPPLNGVILPGVVRQSLLDMAQTWGeFR 272
Cdd:TIGR01123 160 YAASLLAQAKAAEQGCDQVVYLDPVEHTyIEEVGAMNFFFITG--DG--ELVTPPLSGSILPGITRDSLLQLAKDLG-ME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 273 VVERTITMKQLLRALEEGrvREVFGSGTACQVCPVHRILYKDRNLHIPTMENGpELILRFQKELKEIQYGIRA--HEWMF 350
Cdd:TIGR01123 235 VEERRIDIDELKAFVEAG--EIVFACGTAAVITPVGEIQHGGKEVVFASGQPG-EVTKALYDELTDIQYGDFEdpYGWIV 311
|
..
gi 547235678 351 PV 352
Cdd:TIGR01123 312 EV 313
|
|
| PLPDE_IV |
cd00449 |
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, ... |
52-336 |
1.74e-80 |
|
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and 4-amino-4-deoxychorismate lyases (ADCL). BCAT catalyzes the reversible transamination reaction between the L-branched-chain amino and alpha-keto acids. DAAT catalyzes the synthesis of D-glutamic acid and D-alanine, and ADCL converts 4-amino-4-deoxychorismate to p-aminobenzoate and pyruvate. Except for a few enzymes, i. e., Escherichia coli and Salmonella BCATs, which are homohexamers arranged as a double trimer, the class IV PLPDEs are homodimers. Homodimer formation is required for catalytic activity.
Pssm-ID: 238254 [Multi-domain] Cd Length: 256 Bit Score: 245.97 E-value: 1.74e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 52 SSSLHYSLQLFEGMKAFKGkdqqvRLFRPWLNMDRMLRSAMRLCLP-SFDKLELLECIRRLIEVDKdwvpdaaGTSLYVR 130
Cdd:cd00449 1 DRGLHYGDGVFEGLRAGKG-----RLFRLDEHLDRLNRSAKRLGLPiPYDREELREALKELVAANN-------GASLYIR 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 131 PVLIGNEPSLGVSQP--TRALLFVILCPVGAYFPGGSvTPVSLLADPAFIRAWVGGVGNYKLGGNYgPTVLVQQEALKRG 208
Cdd:cd00449 69 PLLTRGVGGLGVAPPpsPEPTFVVFASPVGAYAKGGE-KGVRLITSPDRRRAAPGGTGDAKTGGNL-NSVLAKQEAAEAG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 209 CEQVLWLYGpDHQLTEVGTMNIFVYWtheDGvlELVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRAle 288
Cdd:cd00449 147 ADEALLLDD-NGYVTEGSASNVFIVK---DG--ELVTPPLDGGILPGITRDSVIELAKELG-IKVEERPISLDELYAA-- 217
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 547235678 289 egrvREVFGSGTACQVCPVHRILYKDRnlhipTMENGPELILRFQKEL 336
Cdd:cd00449 218 ----DEVFLTGTAAEVTPVTEIDGRGI-----GDGKPGPVTRKLRELL 256
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
35-342 |
5.34e-70 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 220.06 E-value: 5.34e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 35 WGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGkdqqvRLFRPWLNMDRMLRSAMRLCLP-SFDKLELLECIRRLIE 113
Cdd:COG0115 4 WLNGELVPEEEATISVLDRGLHYGDGVFEGIRAYDG-----RLFRLDEHLARLNRSAKRLGIPiPYTEEELLEAIRELVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 114 VDKDwvpdaagTSLYVRPVLIGNEPSLGVSQPT-RALLFVILCPVGAYFPGGSVTPVSLLADPaFIRAWVGGVGNYKlGG 192
Cdd:COG0115 79 ANGL-------EDGYIRPQVTRGVGGRGVFAEEyEPTVIIIASPLPAYPAEAYEKGVRVITSP-YRRAAPGGLGGIK-TG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 193 NYGPTVLVQQEALKRGCEQVLWLyGPDHQLTEVGTMNIFVYwthEDGVLelVTPPLNGVILPGVVRQSLLDMAQTWGeFR 272
Cdd:COG0115 150 NYLNNVLAKQEAKEAGADEALLL-DTDGYVAEGSGSNVFIV---KDGVL--VTPPLSGGILPGITRDSVIELARELG-IP 222
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 273 VVERTITMKQLLRAleegrvREVFGSGTACQVCPVHRIlykdRNLHIPTMENGPeLILRFQKELKEIQYG 342
Cdd:COG0115 223 VEERPISLEELYTA------DEVFLTGTAAEVTPVTEI----DGRPIGDGKPGP-VTRRLRELYTDIVRG 281
|
|
| PLN02782 |
PLN02782 |
Branched-chain amino acid aminotransferase |
13-315 |
2.06e-58 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 215418 Cd Length: 403 Bit Score: 193.91 E-value: 2.06e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 13 EPLVFGKTFTDHMLMVEWNDKG-WGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSA 91
Cdd:PLN02782 73 DNLGFGLVPTDYMYIMKCNRDGeFSKGELQRFGNIELSPSAGVLNYGQGLFEGLKAYRKEDGNILLFRPEENAIRMRNGA 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 92 MRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSqPTRALLFVI-LCPVGAYFPGGsVTPVS 170
Cdd:PLN02782 153 ERMCMPAPTVEQFVEAVKETVLANKRWVPPPGKGSLYIRPLLMGSGAVLGLA-PAPEYTFLIyVSPVGNYFKEG-VAPIN 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 171 LLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLygpD--HQ--LTEVGTMNIFVYwthEDGVLElvTP 246
Cdd:PLN02782 231 LIVENEFHRATPGGTGGVKTIGNYAAVLKAQSIAKAKGYSDVLYL---DcvHKkyLEEVSSCNIFIV---KDNVIS--TP 302
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 547235678 247 PLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRAleegrvREVFGSGTACQVCPVHRILYKDR 315
Cdd:PLN02782 303 AIKGTILPGITRKSIIDVARSQG-FQVEERNVTVDELLEA------DEVFCTGTAVVVSPVGSITYKGK 364
|
|
| PLN03117 |
PLN03117 |
Branched-chain-amino-acid aminotransferase; Provisional |
13-343 |
5.81e-52 |
|
Branched-chain-amino-acid aminotransferase; Provisional
Pssm-ID: 178664 Cd Length: 355 Bit Score: 175.89 E-value: 5.81e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 13 EPLVFGKTFTDHMLMVEWND-KGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSA 91
Cdd:PLN03117 23 EELGFALVPTDYMYVAKCKQgESFSEGKIVPYGDISISPCAGILNYGQGLFEGLKAYRTEDGRITLFRPDQNALRMQTGA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 92 MRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSvtPVSL 171
Cdd:PLN03117 103 DRLCMTPPSLEQFVEAVKQTVLANKKWVPPPGKGTLYIRPLLIGSGAVLGVAPAPEYTFLIYASPVGNYHKASS--GLNL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 172 LADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWL-YGPDHQLTEVGTMNIFVYwthEDGVLElvTPPLNG 250
Cdd:PLN03117 181 KVDHKHRRAHSGGTGGVKSCTNYSPVVKSLIEAKSSGFSDVLFLdAATGKNIEELSACNIFIL---KGNIVS--TPPTSG 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 251 VILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRAleegrvREVFGSGTACQVCPVHRILYKDRNLHIPTMENGpeLIL 330
Cdd:PLN03117 256 TILPGVTRKSISELARDIG-YQVEERDVSVDELLEA------EEVFCTGTAVVVKAVETVTFHDKKVKYRTGEEA--LST 326
|
330
....*....|...
gi 547235678 331 RFQKELKEIQYGI 343
Cdd:PLN03117 327 KLHLILTNIQMGV 339
|
|
| PLN02883 |
PLN02883 |
Branched-chain amino acid aminotransferase |
15-314 |
1.74e-47 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 178471 Cd Length: 384 Bit Score: 164.89 E-value: 1.74e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 15 LVFGKTFTDHMLMVE-WNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMR 93
Cdd:PLN02883 57 LGFSLVRTDFMFATKsCRDGNFEQGYLSRYGNIELNPAAGILNYGQGLIEGMKAYRGEDGRILLFRPELNAMRMKIGAER 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 94 LCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTpVSLLA 173
Cdd:PLN02883 137 MCMHSPSVHQFIEGVKQTVLANRRWVPPPGKGSLYLRPLLFGSGASLGVAAAPEYTFLVFGSPVQNYFKEGTAA-LNLYV 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 174 DPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYG-PDHQLTEVGTMNIFVYWTHedgvlELVTPPLNGVI 252
Cdd:PLN02883 216 EEVIPRAYLGGTGGVKAISNYGPVLEVMRRAKSRGFSDVLYLDAdTGKNIEEVSAANIFLVKGN-----IIVTPATSGTI 290
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 547235678 253 LPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRAleegrvREVFGSGTACQVCPVHRILYKD 314
Cdd:PLN02883 291 LGGITRKSIIEIALDLG-YKVEERRVPVEELKEA------EEVFCTGTAAGVASVGSITFKN 345
|
|
| PLN02259 |
PLN02259 |
branched-chain-amino-acid aminotransferase 2 |
15-343 |
1.84e-45 |
|
branched-chain-amino-acid aminotransferase 2
Pssm-ID: 177901 Cd Length: 388 Bit Score: 159.89 E-value: 1.84e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 15 LVFGKTFTDHMLMVEWNDKG-WGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMR 93
Cdd:PLN02259 61 LGFGLNPADYMYVMKCSKDGeFTQGELSPYGNIQLSPSAGVLNYGQAIYEGTKAYRKENGKLLLFRPDHNAIRMKLGAER 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 94 LCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGsVTPVSLLA 173
Cdd:PLN02259 141 MLMPSPSVDQFVNAVKQTALANKRWVPPAGKGTLYIRPLLMGSGPILGLGPAPEYTFIVYASPVGNYFKEG-MAALNLYV 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 174 DPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQ-LTEVGTMNIFVYWTHedgvlELVTPPLNGVI 252
Cdd:PLN02259 220 EEEYVRAAPGGAGGVKSITNYAPVLKALSRAKSRGFSDVLYLDSVKKKyLEEASSCNVFVVKGR-----TISTPATNGTI 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 253 LPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRAleegrvREVFGSGTACQVCPVHRILYKDRNLHIPTMENgpELILRF 332
Cdd:PLN02259 295 LEGITRKSVMEIASDQG-YQVVEKAVHVDEVMDA------DEVFCTGTAVVVAPVGTITYQEKRVEYKTGDE--SVCQKL 365
|
330
....*....|.
gi 547235678 333 QKELKEIQYGI 343
Cdd:PLN02259 366 RSVLVGIQTGL 376
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
60-310 |
3.02e-32 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 120.15 E-value: 3.02e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 60 QLFEGMKAFKGkdqqvRLFRPWLNMDRMLRSAMRLCLP-SFDKLELLECIRRLIEVDKDWVPdaagtslYVRPVLIGNEP 138
Cdd:pfam01063 1 GVFETLRVYNG-----KIFFLDEHLARLRRSAKLLGIPlPFDEEDLRKIIEELLKANGLGVG-------RLRLTVSRGPG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 139 SLGVSQPT-RALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAwvggvgNYKlGGNYGPTVLVQQEALKRGCEQVLwLYG 217
Cdd:pfam01063 69 GFGLPTSDpTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLP------GAK-TLNYLENVLARREAKAQGADDAL-LLD 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 218 PDHQLTEVGTMNIFvyWTHEDgvlELVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRAleegrvREVFG 297
Cdd:pfam01063 141 EDGNVTEGSTSNVF--LVKGG---TLYTPPLESGILPGITRQALLDLAKALG-LEVEERPITLADLQEA------DEAFL 208
|
250
....*....|...
gi 547235678 298 SGTACQVCPVHRI 310
Cdd:pfam01063 209 TNSLRGVTPVSSI 221
|
|
| ilvE_I |
TIGR01122 |
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are ... |
35-352 |
8.65e-27 |
|
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family more strongly similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130192 Cd Length: 298 Bit Score: 107.45 E-value: 8.65e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 35 WGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGkDQQVRLFRPWLNMDRMLRSAMRLCLP-SFDKLELLECIRRLIE 113
Cdd:TIGR01122 1 WMDGEFVDWEDAKVHVLTHALHYGTGVFEGIRAYDT-DKGPAIFRLKEHIQRLYDSAKIYRMEiPYSKEELMEATRETLR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 114 VDKDwvpdaagTSLYVRPVLIGNEPSLGVSQP--TRALLFVILCPVGAYfpggsvtpvslLADPAF---IRAWVGGV--- 185
Cdd:TIGR01122 80 KNNL-------RSAYIRPLVFRGDGDLGLNPRagYKPDVIIAAWPWGAY-----------LGEEALekgIDAKVSSWrrn 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 186 ------GNYKLGGNYGPTVLVQQEALKRGCEQVLWLyGPDHQLTEVGTMNIFVYwthEDGVleLVTPPLNGVILPGVVRQ 259
Cdd:TIGR01122 142 apntipTAAKAGGNYLNSLLAKSEARRHGYDEAILL-DVEGYVAEGSGENIFIV---KDGV--LFTPPVTSSILPGITRD 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 260 SLLDMAQTWGeFRVVERTITMKQLLRAleegrvREVFGSGTACQVCPVHRIlykdRNLHIPTMENGPeLILRFQKELKEI 339
Cdd:TIGR01122 216 TVITLAKELG-IEVVEQPISREELYTA------DEAFFTGTAAEITPIREV----DGRKIGNGRRGP-VTKKLQEAFFDL 283
|
330
....*....|....*
gi 547235678 340 QYG-IRAH-EWMFPV 352
Cdd:TIGR01122 284 VTGgTEDYwGWLTYV 298
|
|
| PRK06606 |
PRK06606 |
branched-chain amino acid transaminase; |
27-310 |
5.33e-26 |
|
branched-chain amino acid transaminase;
Pssm-ID: 235841 Cd Length: 306 Bit Score: 105.61 E-value: 5.33e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 27 MVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVrLFRPWLNMDRMLRSA--MRLCLPsFDKLEL 104
Cdd:PRK06606 2 MADRAGYIWFNGELVPWEDAKVHVLTHALHYGTGVFEGIRAYDTPKGPA-IFRLREHTKRLFNSAkiLRMEIP-YSVDEL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 105 LECIRRLIEVDKdwvPDAAgtslYVRP-VLIGNEpSLGVSQ---PTRALLFVIlcPVGAYFPGGS--------------- 165
Cdd:PRK06606 80 MEAQREVVRKNN---LKSA----YIRPlVFVGDE-GLGVRPhglPTDVAIAAW--PWGAYLGEEAlekgirvkvsswtrh 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 166 ---VTPVslladpafiRAwvggvgnyKLGGNYGPTVLVQQEALKRGCEQVLWLyGPDHQLTEVGTMNIFVYwthEDGVle 242
Cdd:PRK06606 150 apnSIPT---------RA--------KASGNYLNSILAKTEARRNGYDEALLL-DVEGYVSEGSGENIFIV---RDGV-- 206
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 547235678 243 LVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRAleegrvREVFGSGTACQVCPVHRI 310
Cdd:PRK06606 207 LYTPPLTSSILEGITRDTVITLAKDLG-IEVIERRITRDELYIA------DEVFFTGTAAEVTPIREV 267
|
|
| D-AAT_like |
cd01558 |
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes ... |
62-310 |
1.33e-18 |
|
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and D-glutamate in addition to other D-amino acids. The enzyme like other members of this superfamily requires PLP as a cofactor. Members of this subgroup are found in all three forms of life.
Pssm-ID: 238799 [Multi-domain] Cd Length: 270 Bit Score: 84.19 E-value: 1.33e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 62 FEGMKAFKGKdqqvrLFRPWLNMDRMLRSAMRLCLPS-FDKLELLECIRRLIEvdKDWVPDAAGtslYVRpVLIGNEP-S 139
Cdd:cd01558 28 YEVIRVYNGK-----PFALDEHLDRLYRSAKELRIDIpYTREELKELIRELVA--KNEGGEGDV---YIQ-VTRGVGPrG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 140 LGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPaFIRaWvgGVGNYKLGgNYGPTVLVQQEALKRGCEQVlWLYGPD 219
Cdd:cd01558 97 HDFPKCVKPTVVIITQPLPLPPAELLEKGVRVITVP-DIR-W--LRCDIKSL-NLLNNVLAKQEAKEAGADEA-ILLDAD 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 220 HQLTEVGTMNIFVYwthEDGVLelVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRAleegrvREVFGSG 299
Cdd:cd01558 171 GLVTEGSSSNVFIV---KNGVL--VTPPLDNGILPGITRATVIELAKELG-IPVEERPFSLEELYTA------DEVFLTS 238
|
250
....*....|.
gi 547235678 300 TACQVCPVHRI 310
Cdd:cd01558 239 TTAEVMPVVEI 249
|
|
| ADCL_like |
cd01559 |
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent ... |
54-310 |
2.17e-16 |
|
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most members of this subgroup are likely to function as dimers. The enzyme from E.Coli, the structure of which is available, is a homodimer that is folded into a small and a larger domain. The coenzyme pyridoxal 5; -phosphate resides at the interface of the two domains that is linked by a flexible loop. Members of this subgroup are found in Eukaryotes and bacteria.
Pssm-ID: 238800 [Multi-domain] Cd Length: 249 Bit Score: 77.73 E-value: 2.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 54 SLHYSLQLFEGMKAFKGkdqQVRLFRPWLnmDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKdwVPDAAGTSLYVRPVL 133
Cdd:cd01559 3 GFAYGDGVFETMRALDG---RLFLLDAHL--ARLERSARRLGIPEPDLPRLRAALESLLAAND--IDEGRIRLILSRGPG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 134 IGNEPSLGVSQPTRaLLFVILCPVGAYFPGGSV--TPVSLLADPAFIRAwvggvgnyKlGGNYGPTVLVQQEALKRGCEQ 211
Cdd:cd01559 76 GRGYAPSVCPGPAL-YVSVIPLPPAWRQDGVRLitCPVRLGEQPLLAGL--------K-HLNYLENVLAKREARDRGADE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 212 VLWLYGPDHqLTEVGTMNIFvyWTHeDGvlELVTPPLNGVILPGVVRQSLLDMAQTWGEfRVVERTITMKQLLRAleegr 291
Cdd:cd01559 146 ALFLDTDGR-VIEGTASNLF--FVK-DG--ELVTPSLDRGGLAGITRQRVIELAAAKGY-AVDERPLRLEDLLAA----- 213
|
250
....*....|....*....
gi 547235678 292 vREVFGSGTACQVCPVHRI 310
Cdd:cd01559 214 -DEAFLTNSLLGVAPVTAI 231
|
|
| PRK08320 |
PRK08320 |
branched-chain amino acid aminotransferase; Reviewed |
62-310 |
6.80e-10 |
|
branched-chain amino acid aminotransferase; Reviewed
Pssm-ID: 236238 [Multi-domain] Cd Length: 288 Bit Score: 59.11 E-value: 6.80e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 62 FEGMKAFKGkdqqvRLFRPWLNMDRMLRSAMRLCL-PSFDKLELLECIrrlIE-VDKDWVPDAagtslYVRPVLIGNEPS 139
Cdd:PRK08320 33 FEGIRAYNG-----RVFRLKEHIDRLYDSAKAIMLeIPLSKEEMTEIV---LEtLRKNNLRDA-----YIRLVVSRGVGD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 140 LGV-----SQPTralLFVILCPVGAYFP-----GGSVTPVSlladpafIRAWVGGVGNYKLGG-NYGPTVLVQQEALKRG 208
Cdd:PRK08320 100 LGLdprkcPKPT---VVCIAEPIGLYPGelyekGLKVITVS-------TRRNRPDALSPQVKSlNYLNNILAKIEANLAG 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 209 CEQVLWLygpDHQ--LTEVGTMNIFVYwthEDGVLelVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVERTITMKQLLRA 286
Cdd:PRK08320 170 VDEAIML---NDEgyVAEGTGDNIFIV---KNGKL--ITPPTYAGALEGITRNAVIEIAKELG-IPVREELFTLHDLYTA 240
|
250 260
....*....|....*....|....
gi 547235678 287 leegrvREVFGSGTACQVCPVHRI 310
Cdd:PRK08320 241 ------DEVFLTGTAAEVIPVVKV 258
|
|
| PRK07544 |
PRK07544 |
branched-chain amino acid aminotransferase; Validated |
27-310 |
4.49e-09 |
|
branched-chain amino acid aminotransferase; Validated
Pssm-ID: 181025 Cd Length: 292 Bit Score: 56.91 E-value: 4.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 27 MVEWNDKgwgqpriqpfqnlTLHPASSSLHYSLQLFEGMKAFKGKdqqvrLFRPWLNMDRMLRSAMRLCLPSFDKLELLE 106
Cdd:PRK07544 17 LVPWRDA-------------KVHVLTHGLHYASSVFEGERAYGGK-----IFKLREHSERLRRSAELLDFEIPYSVAEID 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 107 CIRRLIeVDKDWVPDAagtslYVRPVLIGNEPSLGVS-QPTRALLFVILCPVGAYF-PGGSVTPVSL-LA-----DPAFI 178
Cdd:PRK07544 79 AAKKET-LAANGLTDA-----YVRPVAWRGSEMMGVSaQQNKIHLAIAAWEWPSYFdPEAKMKGIRLdIAkwrrpDPETA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 179 RAwvggvgNYKLGGNYGPTVLVQQEALKRGCEQVLWLygpDH--QLTEVGTMNIFVYwthEDGVLELVTPplnGVILPGV 256
Cdd:PRK07544 153 PS------AAKAAGLYMICTISKHAAEAKGYADALML---DYrgYVAEATGANIFFV---KDGVIHTPTP---DCFLDGI 217
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 547235678 257 VRQSLLDMAQTWGeFRVVERTItmkqllRALEEGRVREVFGSGTACQVCPVHRI 310
Cdd:PRK07544 218 TRQTVIELAKRRG-IEVVERHI------MPEELAGFSECFLTGTAAEVTPVSEI 264
|
|
| PRK13356 |
PRK13356 |
branched-chain amino acid aminotransferase; |
29-317 |
2.76e-07 |
|
branched-chain amino acid aminotransferase;
Pssm-ID: 237362 Cd Length: 286 Bit Score: 51.49 E-value: 2.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 29 EWNDkgwGQPRIqpfqnltLHPASSSLHYSLQLFEGMKAFKGKdqqvrlfRPWLNM--DRMLRSAMRLCL-PSFDKLEL- 104
Cdd:PRK13356 14 EWHE---GNVPI-------MGPADHAAWLGSTVFDGARAFEGV-------TPDLDLhcARVNRSAEALGLkPTVSAEEIe 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 105 ---LECIRRLievdkdwvpdAAGTSLYVRPVLIGNEPSLGVSQP----TRALLFVILCPVGAyfPGGSVTPVSlladpAF 177
Cdd:PRK13356 77 alaREGLKRF----------DPDTALYIRPMYWAEDGFASGVAPdpesTRFALCLEEAPMPE--PTGFSLTLS-----PF 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 178 IRAWVG-GVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHqLTEVGTMNIFVYwthEDGVleLVTPPLNGVILPGV 256
Cdd:PRK13356 140 RRPTLEmAPTDAKAGCLYPNNARALREARSRGFDNALVLDMLGN-VAETATSNVFMV---KDGV--VFTPVPNGTFLNGI 213
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 547235678 257 VRQSLLDMAQTWGeFRVVERTITMKQLLRAleegrvREVFGSGTACQVCPVHRIlyKDRNL 317
Cdd:PRK13356 214 TRQRVIALLREDG-VTVVETTLTYEDFLEA------DEVFSTGNYSKVVPVTRF--DDRSL 265
|
|
| PRK06680 |
PRK06680 |
D-amino acid aminotransferase; Reviewed |
196-310 |
3.35e-06 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 180656 [Multi-domain] Cd Length: 286 Bit Score: 48.00 E-value: 3.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 196 PTVLVQQEALKRGCeQVLWLYGpDHQLTEVGTMNIFVywTHEDGVLelVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVE 275
Cdd:PRK06680 155 PNVLAKQAAKEAGA-QEAWMVD-DGFVTEGASSNAWI--VTKDGKL--VTRPADNFILPGITRHTLIDLAKELG-LEVEE 227
|
90 100 110
....*....|....*....|....*....|....*
gi 547235678 276 RTITMKQLLRAleegrvREVFGSGTACQVCPVHRI 310
Cdd:PRK06680 228 RPFTLQEAYAA------REAFITAASSFVFPVVQI 256
|
|
| PRK12400 |
PRK12400 |
D-amino acid aminotransferase; Reviewed |
28-307 |
1.29e-05 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 171470 Cd Length: 290 Bit Score: 46.16 E-value: 1.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 28 VEWNDKGWGQPRIQPFQNLTlhpaSSSLHYSLQLFEGMKAFKGkdqQVRLFRPwlNMDRMLRS--AMRLCLPsFDKLELL 105
Cdd:PRK12400 7 VLWNDAVIDTTKQKTYIELE----ERGLQFGDGVYEVIRLYKG---NFHLLDP--HITRLYRSmeEIELTLP-FSKAELI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 106 ECIRRLIEvDKDWVPDAagtSLYVrpvlignEPSLGVSQPTRALLFVILCPVGAYFPGGSVTP------VSLLADP--AF 177
Cdd:PRK12400 77 TLLYKLIE-NNNFHEDG---TIYL-------QVSRGVQARTHTFSYDVPPTIYAYITKKERPAlwieygVRAISEPdtRW 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 178 IRAWVGGVgnyklggNYGPTVLVQQEALKRGCEQVLWLYgpDHQLTEVGTMNIFVYwthEDGVLelVTPPLNGVILPGVV 257
Cdd:PRK12400 146 LRCDIKSL-------NLLPNILAATKAERKGCKEALFVR--NGTVTEGSHSNFFLI---KNGTL--YTHPANHLILNGII 211
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 547235678 258 RQSLLDMAQTWgEFRVVERTITMKQLLRAleegrvREVFGSGTACQVCPV 307
Cdd:PRK12400 212 RQYVLSLAKTL-RIPVQEELFSVRDVYQA------DECFFTGTTIEILPM 254
|
|
| PRK07849 |
PRK07849 |
aminodeoxychorismate lyase; |
62-286 |
5.52e-04 |
|
aminodeoxychorismate lyase;
Pssm-ID: 236114 [Multi-domain] Cd Length: 292 Bit Score: 41.10 E-value: 5.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 62 FEGMKAFKGKdqqVRLFRPWLnmDRMLRSAMRLCLPSFDklelLECIRRLIE-VDKDWVPDAAGTSL---YVRpvliGNE 137
Cdd:PRK07849 42 FETLLVRDGR---PCNLEAHL--ERLARSAALLDLPEPD----LDRWRRAVElAIEEWRAPEDEAALrlvYSR----GRE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 138 pslGVSQPTralLFVILCPVGAYFPGGSVTPVSLLADPafiRAWVGGVGN---YKLGG----NYGPTVLVQQEALKRGCE 210
Cdd:PRK07849 109 ---SGGAPT---AWVTVSPVPERVARARREGVSVITLD---RGYPSDAAErapWLLAGaktlSYAVNMAALRYAARRGAD 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 211 QVlwlygpdhqltevgtmnIFvywTHEDG-VLE-------------LVTPPLNGVILPGVVRQSLLDMAQTWGeFRVVER 276
Cdd:PRK07849 180 DV-----------------IF---TSTDGyVLEgptstvviatddrLLTPPPWYGILPGTTQAALFEVAREKG-WDCEYR 238
|
250
....*....|
gi 547235678 277 TITMKQLLRA 286
Cdd:PRK07849 239 ALRPADLFAA 248
|
|
| PRK12479 |
PRK12479 |
branched-chain-amino-acid transaminase; |
193-310 |
9.95e-04 |
|
branched-chain-amino-acid transaminase;
Pssm-ID: 183549 [Multi-domain] Cd Length: 299 Bit Score: 40.32 E-value: 9.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 193 NYGPTVLVQQEALKRGCEQVLWLyGPDHQLTEVGTMNIFVYwthEDGvlELVTPPLNGVILPGVVRQSLLDMAQTWGeFR 272
Cdd:PRK12479 155 NYLNNVLVKIEAAQAGVLEALML-NQQGYVCEGSGDNVFVV---KDG--KVLTPPSYLGALEGITRNSVIELCERLS-IP 227
|
90 100 110
....*....|....*....|....*....|....*...
gi 547235678 273 VVERTITMKQLLRAleegrvREVFGSGTACQVCPVHRI 310
Cdd:PRK12479 228 CEERPFTRHDVYVA------DEVFLTGTAAELIPVVKV 259
|
|
| PLN02845 |
PLN02845 |
Branched-chain-amino-acid aminotransferase-like protein |
193-288 |
1.12e-03 |
|
Branched-chain-amino-acid aminotransferase-like protein
Pssm-ID: 215454 [Multi-domain] Cd Length: 336 Bit Score: 40.38 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 547235678 193 NYGPTVLVQQEALKRGCEQVLWLYGpDHQLTEVGTMNI-FVywTHEDgvlELVTPPLNGvILPGVVRQSLLDMAQTW--- 268
Cdd:PLN02845 188 NYLPNALSQMEAEERGAFAGIWLDE-EGFVAEGPNMNVaFL--TNDG---ELVLPPFDK-ILSGCTARRVLELAPRLvsp 260
|
90 100
....*....|....*....|.
gi 547235678 269 GEFRVVE-RTITMKQLLRALE 288
Cdd:PLN02845 261 GDLRGVKqRKISVEEAKAADE 281
|
|
| PRK07546 |
PRK07546 |
hypothetical protein; Provisional |
221-286 |
8.63e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 169002 [Multi-domain] Cd Length: 209 Bit Score: 36.88 E-value: 8.63e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 547235678 221 QLTEVGTMNIFVywthEDGVLELVTPPLNGVILPGVVRQSLLDmaqtwgEFRVVERTITMKQLLRA 286
Cdd:PRK07546 136 EVCEGTITNVFL----DRGGGMLTTPPLSCGLLPGVLRAELLD------AGRAREAVLTVDDLKSA 191
|
|
| |
