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Conserved domains on  [gi|543385146|gb|ERJ43359|]
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phospholipid phosphatase [Lactobacillus jensenii MD IIE-70(2)]

Protein Classification

phosphatase PAP2 family protein( domain architecture ID 10130261)

type 2 phosphatidic acid phosphatase (PAP2) family protein similar to Bacillus subtilis phosphatidylglycerophosphatase B that catalyzes the dephosphorylation of phosphatidylglycerophosphate (PGP) to phosphatidylglycerol

CATH:  1.20.144.10
EC:  3.1.3.-
Gene Ontology:  GO:0016020|GO:0016791|GO:1901137|GO:0006629
PubMed:  9122162
SCOP:  3001110

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 27-205 1.19e-37

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


:

Pssm-ID: 239486  Cd Length: 182  Bit Score: 128.88  E-value: 1.19e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  27 SVAYQASFIKGFDKLFINLIANQNKTEL-FILKHLTVLANTPVVIGYTVVLVIFLLLKRKYALAGFSTFVMALANGNNWL 105
Cdd:cd03392    1 AVVVQAGWLTAFDQSVLSLLRSLRTPLLtAFMTAITFLGSPAVLLIIVLLLALLLLLKRRRRAALFLLLALLGGGALNTL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146 106 LKHIVQRPRPAVSHLVKATGYSFPSGHSAGSMSICLVLFVVVLILMNKGLLKRLLLIILPIIPFIIGMSRIYVHVHYPSD 185
Cdd:cd03392   81 LKLLVQRPRPPLHLLVPEGGYSFPSGHAMGATVLYGFLAYLLARRLPRRRVRILLLILAAILILLVGLSRLYLGVHYPSD 160

                        170       180
                 ....*....|....*....|
gi 543385146 186 VLGGFIEAITYFLLGLLIFQ 205
Cdd:cd03392  161 VLAGWLLGLAWLALLILLYR 180
 
Name Accession Description Interval E-value
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 27-205 1.19e-37

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 128.88  E-value: 1.19e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  27 SVAYQASFIKGFDKLFINLIANQNKTEL-FILKHLTVLANTPVVIGYTVVLVIFLLLKRKYALAGFSTFVMALANGNNWL 105
Cdd:cd03392    1 AVVVQAGWLTAFDQSVLSLLRSLRTPLLtAFMTAITFLGSPAVLLIIVLLLALLLLLKRRRRAALFLLLALLGGGALNTL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146 106 LKHIVQRPRPAVSHLVKATGYSFPSGHSAGSMSICLVLFVVVLILMNKGLLKRLLLIILPIIPFIIGMSRIYVHVHYPSD 185
Cdd:cd03392   81 LKLLVQRPRPPLHLLVPEGGYSFPSGHAMGATVLYGFLAYLLARRLPRRRVRILLLILAAILILLVGLSRLYLGVHYPSD 160

                        170       180
                 ....*....|....*....|
gi 543385146 186 VLGGFIEAITYFLLGLLIFQ 205
Cdd:cd03392  161 VLAGWLLGLAWLALLILLYR 180
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 19-205 2.19e-17

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 76.62  E-value: 2.19e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  19 AFYAFWAFSVAYQASFIKGFDKLFINLIANQNKTELFILKHLTVLANTPVVIGYTVVLVIFLLLKRKYALAGFSTFVMAL 98
Cdd:COG0671    1 LLLALLLALLLLLLLLADLLALALLALLLLLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  99 ANGNNW----LLKHIVQRPRPAVS-----HLVKATGYSFPSGHSAGSMSICLVLFVVVLILmnkgllkrLLLIILPIIPF 169
Cdd:COG0671   81 LLLLLLllllLLKYLFGRPRPFVVpdlelLLGTAGGYSFPSGHAAAAFALALVLALLLPRR--------WLAALLLALAL 152

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 543385146 170 IIGMSRIYVHVHYPSDVLGGFIEAITYFLLGLLIFQ 205
Cdd:COG0671  153 LVGLSRVYLGVHYPSDVLAGALLGLAIALLLLALLR 188
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 94-205 7.49e-11

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 57.43  E-value: 7.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146   94 FVMALANGNNWLLKHIVQRPRPAVSHLVKAT----------GYSFPSGHSAGSMSICLVLFVVVLIlmNKGLLKRLLLII 163
Cdd:pfam01569   4 LALALAGLLSSVLKDYFGRPRPFFLLLEGGLvpapstlpglGYSFPSGHSATAFALALLLALLLRR--LRKIVRVLLALL 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 543385146  164 LPIIPFIIGMSRIYVHVHYPSDVLGGFIEAITYFLLGLLIFQ 205
Cdd:pfam01569  82 LLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLVYRLVP 123
acidPPc smart00014
Acid phosphatase homologues;
94-199 1.25e-10

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 56.59  E-value: 1.25e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146    94 FVMALANGNNWLLKHIVQRPRPAV-----------SHLVKATGYSFPSGHSAGSMSICLVLFVVVLILMNKgllkRLLLI 162
Cdd:smart00014   2 LLAVVSQLFNGVIKNYFGRPRPFFlsigdacctpnFLLTLEAGYSFPSGHTAFAFAFALFLLLYLPARAGR----KLLIF 77

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 543385146   163 ILPIIPFIIGMSRIYVHVHYPSDVLGGFIEAITYFLL 199
Cdd:smart00014  78 LLLLLALVVGFSRVYLGAHWPSDVLAGSLLGILIAAV 114
 
Name Accession Description Interval E-value
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 27-205 1.19e-37

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 128.88  E-value: 1.19e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  27 SVAYQASFIKGFDKLFINLIANQNKTEL-FILKHLTVLANTPVVIGYTVVLVIFLLLKRKYALAGFSTFVMALANGNNWL 105
Cdd:cd03392    1 AVVVQAGWLTAFDQSVLSLLRSLRTPLLtAFMTAITFLGSPAVLLIIVLLLALLLLLKRRRRAALFLLLALLGGGALNTL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146 106 LKHIVQRPRPAVSHLVKATGYSFPSGHSAGSMSICLVLFVVVLILMNKGLLKRLLLIILPIIPFIIGMSRIYVHVHYPSD 185
Cdd:cd03392   81 LKLLVQRPRPPLHLLVPEGGYSFPSGHAMGATVLYGFLAYLLARRLPRRRVRILLLILAAILILLVGLSRLYLGVHYPSD 160

                        170       180
                 ....*....|....*....|
gi 543385146 186 VLGGFIEAITYFLLGLLIFQ 205
Cdd:cd03392  161 VLAGWLLGLAWLALLILLYR 180
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 19-205 2.19e-17

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 76.62  E-value: 2.19e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  19 AFYAFWAFSVAYQASFIKGFDKLFINLIANQNKTELFILKHLTVLANTPVVIGYTVVLVIFLLLKRKYALAGFSTFVMAL 98
Cdd:COG0671    1 LLLALLLALLLLLLLLADLLALALLALLLLLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  99 ANGNNW----LLKHIVQRPRPAVS-----HLVKATGYSFPSGHSAGSMSICLVLFVVVLILmnkgllkrLLLIILPIIPF 169
Cdd:COG0671   81 LLLLLLllllLLKYLFGRPRPFVVpdlelLLGTAGGYSFPSGHAAAAFALALVLALLLPRR--------WLAALLLALAL 152

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 543385146 170 IIGMSRIYVHVHYPSDVLGGFIEAITYFLLGLLIFQ 205
Cdd:COG0671  153 LVGLSRVYLGVHYPSDVLAGALLGLAIALLLLALLR 188
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 86-199 5.75e-14

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 65.94  E-value: 5.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  86 YALAGFSTFVMALANGNNWLLKHIVQRPRP---------AVSHLVKATGYSFPSGHSAGSMSICLVLFVVVLILMNKgll 156
Cdd:cd01610    2 RLLALLLLLALLAGLLLTGVLKYLFGRPRPyfllrcgpdGDPLLLTEGGYSFPSGHAAFAFALALFLALLLPRRLLR--- 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 543385146 157 kRLLLIILPIIPFIIGMSRIYVHVHYPSDVLGGFIEAITYFLL 199
Cdd:cd01610   79 -LLLGLLLLLLALLVGLSRVYLGVHYPSDVLAGALLGILVALL 120
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 94-205 7.49e-11

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 57.43  E-value: 7.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146   94 FVMALANGNNWLLKHIVQRPRPAVSHLVKAT----------GYSFPSGHSAGSMSICLVLFVVVLIlmNKGLLKRLLLII 163
Cdd:pfam01569   4 LALALAGLLSSVLKDYFGRPRPFFLLLEGGLvpapstlpglGYSFPSGHSATAFALALLLALLLRR--LRKIVRVLLALL 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 543385146  164 LPIIPFIIGMSRIYVHVHYPSDVLGGFIEAITYFLLGLLIFQ 205
Cdd:pfam01569  82 LLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLVYRLVP 123
PAP2_like_4 cd03395
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 74-205 1.21e-10

PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239489  Cd Length: 177  Bit Score: 58.04  E-value: 1.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  74 VVLVIFLLLKR---KYALAGFSTFVMALANG-NNWLLKHIVQRPRP-----AVSHLVKAT---GYSFPSGHSAGSMSICL 141
Cdd:cd03395   40 LLLALFILFRKgpiGLLILLLVLLAVGFADQlASGFLKPLVARLRPcnaldGVRLVVLGDqggSYSFASSHAANSFALAL 119

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543385146 142 VLFVVVLILmnkgllkrLLLIILPIIPFIIGMSRIYVHVHYPSDVLGGFIEAITYFLLGLLIFQ 205
Cdd:cd03395  120 FIWLFFRRG--------LFSPVLLLWALLVGYSRVYVGVHYPGDVIAGALIGIISGLLFYLLFS 175
acidPPc smart00014
Acid phosphatase homologues;
94-199 1.25e-10

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 56.59  E-value: 1.25e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146    94 FVMALANGNNWLLKHIVQRPRPAV-----------SHLVKATGYSFPSGHSAGSMSICLVLFVVVLILMNKgllkRLLLI 162
Cdd:smart00014   2 LLAVVSQLFNGVIKNYFGRPRPFFlsigdacctpnFLLTLEAGYSFPSGHTAFAFAFALFLLLYLPARAGR----KLLIF 77

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 543385146   163 ILPIIPFIIGMSRIYVHVHYPSDVLGGFIEAITYFLL 199
Cdd:smart00014  78 LLLLLALVVGFSRVYLGAHWPSDVLAGSLLGILIAAV 114
PAP2_dolichyldiphosphatase cd03382
PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a ...
 74-191 2.93e-06

PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a membrane-associated protein located in the endoplasmic reticulum and hydrolyzes dolichyl pyrophosphate, as well as dolichylmonophosphate at a low rate. The enzyme is necessary for maintaining proper levels of dolichol-linked oligosaccharides and protein N-glycosylation, and might play a role in re-utilization of the glycosyl carrier lipid for additional rounds of lipid intermediate biosynthesis after its release during protein N-glycosylation reactions.


Pssm-ID: 239477  Cd Length: 159  Bit Score: 45.73  E-value: 2.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  74 VVLVIFLLLKRKYALAGFSTFVMALAN-GNNWLLKHIVQRPRPAVSHLVKATGYSFPSGHSAGSMSICLVLFVVVLILM- 151
Cdd:cd03382   28 ILVGYATLILFRRELEAIYLFIGLLANeALNYVLKRIIKEPRPCSGAYFVRSGYGMPSSHSQFMGFFAVYLLLFIYLRLg 107

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 543385146 152 --NKGLLKRLLLIILPIIPFIIGMSRIYVHVHYPSDVLGGFI 191
Cdd:cd03382  108 rlNSLVSRFLLSLGLLLLALLVSYSRVYLGYHTVSQVVVGAI 149
PAP2_like_3 cd03393
PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 76-200 4.66e-06

PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria and archaea, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239487 [Multi-domain]  Cd Length: 125  Bit Score: 44.28  E-value: 4.66e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  76 LVIFLLLKRKyalaGFSTFVMALANG-NNWLLKHIVQRPRP------AVSHLVKATGYSFPSGHSAGSMSICLVLFVVVL 148
Cdd:cd03393    5 LIYWLVDKRL----GRYLGLALCASGyLNAALKEVFKIPRPftydgiQAIYEESAGGYGFPSGHAQTSATFWGSLMLHVR 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 543385146 149 ILmnkgllkrLLLIILPIIPFIIGMSRIYVHVHYPSDVLGGFIEAITYFLLG 200
Cdd:cd03393   81 KK--------WFTLIGVVLVVLISFSRLYLGVHWPSDVIGGVLIGLLVLVLG 124
PAP2_BcrC_like cd03385
PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as ...
 72-201 9.11e-06

PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from Bacillus subtilis posesses undecaprenyl pyrophosphate (UPP) phospatase activity, and it is hypothesized that it competes with bacitracin for UPP, increasing the cell's resistance to bacitracin.


Pssm-ID: 239480  Cd Length: 144  Bit Score: 43.79  E-value: 9.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  72 YTVVLVIFLLL---------KRKYALagFSTFVMALANGNNWLLKHIVQRPRPAVSHLV-----KATGYSFPSGHSAGSM 137
Cdd:cd03385   11 YLIYILPLLLVvlwlwggekQRKVVL--FATIAVAVALLINYIIGLLYFHPRPFVVGLGhnllpHAADSSFPSDHTTLFF 88

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543385146 138 SICLVLFVVVLILmnkgllkrlLLIILPIIPFIIGMSRIYVHVHYPSDVLGGFIEAITYFLLGL 201
Cdd:cd03385   89 SIAFSLLLRRRKW---------AGWILLILALLVAWSRIYLGVHYPLDMLGAALVAVLSALLVF 143
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 106-201 7.14e-05

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 41.53  E-value: 7.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146 106 LKHIVQRPRPAVSHL-----VKATGYSFPSGHSAGSMSICLVLFvvvlilmNKGLLKRLLLIILPIIPFIIGMSRIYVHV 180
Cdd:cd03391   66 LKALVRRRRPAYNSPdmldyVAVDKYSFPSGHASRAAFVARFLL-------NHLVLAVPLRVLLVLWATVVGISRVLLGR 138

                         90       100
                 ....*....|....*....|.
gi 543385146 181 HYPSDVLGGFIEAITYFLLGL 201
Cdd:cd03391  139 HHVLDVLAGAFLGYLEALLVE 159
PAP2_like_5 cd03394
PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 93-189 9.06e-05

PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239488 [Multi-domain]  Cd Length: 106  Bit Score: 40.39  E-value: 9.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543385146  93 TFVMALANGNNWLLKHIVQRPRPAVShlvkATGY-SFPSGHSAGSMSIclvlfvvvLILMNKGLLKRLLLIILPIIPFII 171
Cdd:cd03394    9 AEAAALTAAVTEGLKFAVGRARPDGS----NNGYrSFPSGHTASAFAA--------ATFLQYRYGWRWYGIPAYALASLV 76

                         90
                 ....*....|....*...
gi 543385146 172 GMSRIYVHVHYPSDVLGG 189
Cdd:cd03394   77 GASRVVANRHWLSDVLAG 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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