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Conserved domains on  [gi|530723526|gb|AGT42502|]
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Rep protein [Cotton leaf curl Gezira alphasatellite]

Protein Classification

replication-associated family protein( domain architecture ID 10261052)

replication-associated family protein similar to replication-associated protein and Para-Rep C1/7/9, both of which are ATP-dependent helicases

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Viral_Rep super family cl03577
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 6-87 6.53e-25

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


The actual alignment was detected with superfamily member pfam02407:

Pssm-ID: 280553  Cd Length: 82  Bit Score: 94.94  E-value: 6.53e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530723526    6 SVCWCFTLNFTGEIPQLdFSNKGVQYAVWQHEKVN--HDHLQGFFQFKGRRSLLQAKKVFDGyHPHLEVMRApSAEQAKK 83
Cdd:pfam02407   1 ARCWCFTLNNPTEFLSL-FSQDELKYFVYQDERGTtgTKHLQGFVEFKNRTSLGQMKKKFPG-RAHLEIARG-SQEEARD 77


                  ....
gi 530723526   84 YCEK 87
Cdd:pfam02407  78 YCMK 81
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 174-270 8.90e-14

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


:

Pssm-ID: 459992  Cd Length: 102  Bit Score: 66.09  E-value: 8.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530723526  174 IWVYGPTGgEGKSQFARYL--------GLNKSWIYlPGGKSNDMMYMYcKSPRCNLVIDYPRCNKEyinysFLEMIKNRT 245
Cdd:pfam00910   1 IWLYGPPG-CGKSTLAKYLarallkklGLPKDSVY-SRNPDDDFWDGY-TGQPVVIIDDFGQNPDG-----PDEAELIRL 72

                          90       100       110
                  ....*....|....*....|....*....|...
gi 530723526  246 IYSYKYEPVG--------FIDPtcnVHVIVMAN 270
Cdd:pfam00910  73 VSSTPYPPPMaaleekgtPFTS---KFVIVTSN 102
 
Name Accession Description Interval E-value
Viral_Rep pfam02407
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 6-87 6.53e-25

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


Pssm-ID: 280553  Cd Length: 82  Bit Score: 94.94  E-value: 6.53e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530723526    6 SVCWCFTLNFTGEIPQLdFSNKGVQYAVWQHEKVN--HDHLQGFFQFKGRRSLLQAKKVFDGyHPHLEVMRApSAEQAKK 83
Cdd:pfam02407   1 ARCWCFTLNNPTEFLSL-FSQDELKYFVYQDERGTtgTKHLQGFVEFKNRTSLGQMKKKFPG-RAHLEIARG-SQEEARD 77


                  ....
gi 530723526   84 YCEK 87
Cdd:pfam02407  78 YCMK 81
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 174-270 8.90e-14

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 66.09  E-value: 8.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530723526  174 IWVYGPTGgEGKSQFARYL--------GLNKSWIYlPGGKSNDMMYMYcKSPRCNLVIDYPRCNKEyinysFLEMIKNRT 245
Cdd:pfam00910   1 IWLYGPPG-CGKSTLAKYLarallkklGLPKDSVY-SRNPDDDFWDGY-TGQPVVIIDDFGQNPDG-----PDEAELIRL 72

                          90       100       110
                  ....*....|....*....|....*....|...
gi 530723526  246 IYSYKYEPVG--------FIDPtcnVHVIVMAN 270
Cdd:pfam00910  73 VSSTPYPPPMaaleekgtPFTS---KFVIVTSN 102
 
Name Accession Description Interval E-value
Viral_Rep pfam02407
Putative viral replication protein; This is a family of viral ORFs from various plant and ...
 6-87 6.53e-25

Putative viral replication protein; This is a family of viral ORFs from various plant and animal ssDNA circoviruses. Published evidence to support the annotated function "viral replication associated protein" has not be found.


Pssm-ID: 280553  Cd Length: 82  Bit Score: 94.94  E-value: 6.53e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530723526    6 SVCWCFTLNFTGEIPQLdFSNKGVQYAVWQHEKVN--HDHLQGFFQFKGRRSLLQAKKVFDGyHPHLEVMRApSAEQAKK 83
Cdd:pfam02407   1 ARCWCFTLNNPTEFLSL-FSQDELKYFVYQDERGTtgTKHLQGFVEFKNRTSLGQMKKKFPG-RAHLEIARG-SQEEARD 77


                  ....
gi 530723526   84 YCEK 87
Cdd:pfam02407  78 YCMK 81
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 174-270 8.90e-14

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 66.09  E-value: 8.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530723526  174 IWVYGPTGgEGKSQFARYL--------GLNKSWIYlPGGKSNDMMYMYcKSPRCNLVIDYPRCNKEyinysFLEMIKNRT 245
Cdd:pfam00910   1 IWLYGPPG-CGKSTLAKYLarallkklGLPKDSVY-SRNPDDDFWDGY-TGQPVVIIDDFGQNPDG-----PDEAELIRL 72

                          90       100       110
                  ....*....|....*....|....*....|...
gi 530723526  246 IYSYKYEPVG--------FIDPtcnVHVIVMAN 270
Cdd:pfam00910  73 VSSTPYPPPMaaleekgtPFTS---KFVIVTSN 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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