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Conserved domains on  [gi|530433305|ref|XP_005278171|]
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armadillo repeat-containing X-linked protein 2 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Arm_2 pfam04826
Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain ...
 383-601 6.58e-116

Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.


:

Pssm-ID: 461447 [Multi-domain]  Cd Length: 221  Bit Score: 344.78  E-value: 6.58e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQ 462
Cdd:pfam04826   1 LEPQELDKLLALLKSSEDPFIHEIALITLGNSAAYPFNQDIIRDLGGIPIIANLLSDSNPEVKEKALNALNNLSMNVENQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  463 GRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDML 542
Cdd:pfam04826  81 KKIKVYVNQVCKDIVSSPLNSEVQLAGLKLLTNLSVTNDYHHLVVSYIRDFFSLLSQGNEKTKFQVLKVLLNLSENPAMT 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530433305  543 KKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLRAE--VFNYREFNKGSLFYLCT 601
Cdd:pfam04826 161 RELLSAQVPSSLLSLFNSKEAKENLLRALTIFENINFHLKKEakLFVKEHFTKGSLFSIFR 221
PRK07003 super family cl35530
DNA polymerase III subunit gamma/tau;
39-279 2.00e-08

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07003:

Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.55  E-value: 2.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  39 AKPKNRAVAGTGARARAGLRAGftidlgsgfspPTPVRAEAEDRAQDEASAldtVGAEAVAPAASSAEAQSGAgsqaqEA 118
Cdd:PRK07003 379 AVPAPGARAAAAVGASAVPAVT-----------AVTGAAGAALAPKAAAAA---AATRAEAPPAAPAPPATAD-----RG 439

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 119 DGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPR-EAETSRAAVPPGTVVPTEAAAPTEVTEGP 197
Cdd:PRK07003 440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfEPAPRAAAPSAATPAAVPDARAPAAASRE 519

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 198 GVAAPTKVAeAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRtavvpGTSAAKKATPGAHTGAIPKATSATGA 277
Cdd:PRK07003 520 DAPAAAAPP-APEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDR-----GARAAAAAKPAAAPAAAPKPAAPRVA 593


                 ..
gi 530433305 278 VP 279
Cdd:PRK07003 594 VQ 595
 
Name Accession Description Interval E-value
Arm_2 pfam04826
Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain ...
 383-601 6.58e-116

Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.


Pssm-ID: 461447 [Multi-domain]  Cd Length: 221  Bit Score: 344.78  E-value: 6.58e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQ 462
Cdd:pfam04826   1 LEPQELDKLLALLKSSEDPFIHEIALITLGNSAAYPFNQDIIRDLGGIPIIANLLSDSNPEVKEKALNALNNLSMNVENQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  463 GRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDML 542
Cdd:pfam04826  81 KKIKVYVNQVCKDIVSSPLNSEVQLAGLKLLTNLSVTNDYHHLVVSYIRDFFSLLSQGNEKTKFQVLKVLLNLSENPAMT 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530433305  543 KKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLRAE--VFNYREFNKGSLFYLCT 601
Cdd:pfam04826 161 RELLSAQVPSSLLSLFNSKEAKENLLRALTIFENINFHLKKEakLFVKEHFTKGSLFSIFR 221
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
39-279 2.00e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.55  E-value: 2.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  39 AKPKNRAVAGTGARARAGLRAGftidlgsgfspPTPVRAEAEDRAQDEASAldtVGAEAVAPAASSAEAQSGAgsqaqEA 118
Cdd:PRK07003 379 AVPAPGARAAAAVGASAVPAVT-----------AVTGAAGAALAPKAAAAA---AATRAEAPPAAPAPPATAD-----RG 439

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 119 DGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPR-EAETSRAAVPPGTVVPTEAAAPTEVTEGP 197
Cdd:PRK07003 440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfEPAPRAAAPSAATPAAVPDARAPAAASRE 519

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 198 GVAAPTKVAeAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRtavvpGTSAAKKATPGAHTGAIPKATSATGA 277
Cdd:PRK07003 520 DAPAAAAPP-APEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDR-----GARAAAAAKPAAAPAAAPKPAAPRVA 593


                 ..
gi 530433305 278 VP 279
Cdd:PRK07003 594 VQ 595
VATPase_H cd00256
VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the ...
 388-455 1.68e-03

VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The topology is that of a superhelical spiral, in part the geometry is similar to superhelices composed of armadillo repeat motifs, as found in importins for example.


Pssm-ID: 238159 [Multi-domain]  Cd Length: 429  Bit Score: 41.23  E-value: 1.68e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530433305 388 LRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
Cdd:cd00256  355 LKILIHLLETSVDPIILAVACHDIGEYVRhYPRGKDVVEQLGGKQRVMRLLNHEDPNVRYEALLAVQKL 423
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 420-456 2.33e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.87  E-value: 2.33e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 530433305   420 NQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLS 456
Cdd:smart00185   4 NKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
KLF9_13_N-like cd21975
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ...
 164-290 8.54e-03

Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.


Pssm-ID: 409240 [Multi-domain]  Cd Length: 163  Bit Score: 37.36  E-value: 8.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 164 AEAPREAETSRAAVPPG----TVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESP 239
Cdd:cd21975   31 AAGLDVRATREVAKGPGppgpAWKPDGADSPGLVTAAPHLLAANVLAPLRGPSVEGSSLESGDADMGSDSDVAPASGAAA 110

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 530433305 240 GTSgsprtavvPGTSAAKKATPGAHTGAIPKATSATGAVPKGGGKGVTRSR 290
Cdd:cd21975  111 STS--------PESSSDAASSPSPLSLLHPGEAGLEPERPRPRVRRGVRRR 153
 
Name Accession Description Interval E-value
Arm_2 pfam04826
Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain ...
 383-601 6.58e-116

Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.


Pssm-ID: 461447 [Multi-domain]  Cd Length: 221  Bit Score: 344.78  E-value: 6.58e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQ 462
Cdd:pfam04826   1 LEPQELDKLLALLKSSEDPFIHEIALITLGNSAAYPFNQDIIRDLGGIPIIANLLSDSNPEVKEKALNALNNLSMNVENQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  463 GRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDML 542
Cdd:pfam04826  81 KKIKVYVNQVCKDIVSSPLNSEVQLAGLKLLTNLSVTNDYHHLVVSYIRDFFSLLSQGNEKTKFQVLKVLLNLSENPAMT 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530433305  543 KKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLRAE--VFNYREFNKGSLFYLCT 601
Cdd:pfam04826 161 RELLSAQVPSSLLSLFNSKEAKENLLRALTIFENINFHLKKEakLFVKEHFTKGSLFSIFR 221
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
39-279 2.00e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.55  E-value: 2.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  39 AKPKNRAVAGTGARARAGLRAGftidlgsgfspPTPVRAEAEDRAQDEASAldtVGAEAVAPAASSAEAQSGAgsqaqEA 118
Cdd:PRK07003 379 AVPAPGARAAAAVGASAVPAVT-----------AVTGAAGAALAPKAAAAA---AATRAEAPPAAPAPPATAD-----RG 439

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 119 DGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPR-EAETSRAAVPPGTVVPTEAAAPTEVTEGP 197
Cdd:PRK07003 440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfEPAPRAAAPSAATPAAVPDARAPAAASRE 519

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 198 GVAAPTKVAeAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRtavvpGTSAAKKATPGAHTGAIPKATSATGA 277
Cdd:PRK07003 520 DAPAAAAPP-APEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDR-----GARAAAAAKPAAAPAAAPKPAAPRVA 593


                 ..
gi 530433305 278 VP 279
Cdd:PRK07003 594 VQ 595
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
49-280 9.31e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 55.24  E-value: 9.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  49 TGARARAGLR----AGFTIDL---------------GSGFSPPTPVRA--EAEDRAQDEASALDTVGAEAVAPAASSAEA 107
Cdd:PRK07003 332 TVGRGELGLApdeyAGFTMTLlrmlafepavtgggaPGGGVPARVAGAvpAPGARAAAAVGASAVPAVTAVTGAAGAALA 411

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 108 QSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEA 187
Cdd:PRK07003 412 PKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFE 491

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 188 AAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATP--GAHT 265
Cdd:PRK07003 492 PAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSdrGARA 571

                        250
                 ....*....|....*
gi 530433305 266 GAIPKATSATGAVPK 280
Cdd:PRK07003 572 AAAAKPAAAPAAAPK 586
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
59-272 2.44e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 53.73  E-value: 2.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  59 AGFTIDL-----------GSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKA 127
Cdd:PRK12323 351 AGFTMTLlrmlafrpgqsGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAP 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 128 ESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEV---TEGPG-VAAPT 203
Cdd:PRK12323 431 EALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPppwEELPPeFASPA 510

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530433305 204 KVAEAPGVAsPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKAT 272
Cdd:PRK12323 511 PAQPDAAPA-GWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFD 578
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
97-282 3.15e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 53.70  E-value: 3.15e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  97 AVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPG-VTEALGAAEAPAMAGAPKVAEAPREA----- 170
Cdd:PRK07003 357 AFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGaAGAALAPKAAAAAAATRAEAPPAAPAppata 436

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 171 -ETSRAAVPPGTVvPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAV 249
Cdd:PRK07003 437 dRGDDAADGDAPV-PAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAA 515

                        170       180       190
                 ....*....|....*....|....*....|...
gi 530433305 250 VPGTSAAKKATPGAHTGAIPKATSATGAVPKGG 282
Cdd:PRK07003 516 ASREDAPAAAAPPAPEARPPTPAAAAPAARAGG 548
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 35-271 1.69e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 51.14  E-value: 1.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  35 KKRMAKPKNRAVAGTGARARAGLRAGFT--IDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAvAPAASSAEAQSGAG 112
Cdd:PRK07764 558 ARRFASPGNAEVLVTALAEELGGDWQVEavVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPA-APAAPAPAGAAAAP 636

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 113 SQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagapkvAEAPREAETSRAAVPPGTVVPTEAAAPTE 192
Cdd:PRK07764 637 AEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAK---------------AGGAAPAAPPPAPAPAAPAAPAGAAPAQP 701

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530433305 193 VTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKA 271
Cdd:PRK07764 702 APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
PHA03247 PHA03247
large tegument protein UL36; Provisional
 71-281 1.40e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 1.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305   71 PPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQ------EADGAGVGPKAESVVGAAMASAIAPPPG 144
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSArprapvDDRGDPRGPAPPSPLPPDTHAPDPPPPS 2630

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  145 VTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGpgvaaPTKVAEAPGVASPTEAAEAPvpa 224
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQR-----PRRRAARPTVGSLTSLADPP--- 2702

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 530433305  225 tptgaaAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPKG 281
Cdd:PHA03247 2703 ------PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG 2753
PHA03247 PHA03247
large tegument protein UL36; Provisional
 11-280 1.94e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 1.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305   11 AAGIVIGAGAWYCVYKYTRGRDQTKKRMAKPKNRAVA-GTGARARAGLR------AGFTIDLGSGFSPPTPVRAEAEDRA 83
Cdd:PHA03247 2633 PAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRlGRAAQASSPPQrprrraARPTVGSLTSLADPPPPPPTPEPAP 2712

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305   84 QDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagaPKV 163
Cdd:PHA03247 2713 HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA------------GPP 2780

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  164 AEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPvpatptgaaaPTGAAESPGTSG 243
Cdd:PHA03247 2781 RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTA----------PPPPPGPPPPSL 2850

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 530433305  244 SPRTAVVPGTSAAKKATPGAhtgaiPKATSATGAVPK 280
Cdd:PHA03247 2851 PLGGSVAPGGDVRRRPPSRS-----PAAKPAAPARPP 2882
PHA03247 PHA03247
large tegument protein UL36; Provisional
 71-282 3.11e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 3.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305   71 PPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVG-----PKAESVVGAAMASAIAPPPGV 145
Cdd:PHA03247 2627 PPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrprrRAARPTVGSLTSLADPPPPPP 2706

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  146 TEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEV--------TEGPG--------VAAPTKVAEAP 209
Cdd:PHA03247 2707 TPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGParparpptTAGPPapappaapAAGPPRRLTRP 2786

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530433305  210 GVASPTEAAEA-PVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPKGG 282
Cdd:PHA03247 2787 AVASLSESRESlPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG 2860
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 83-223 1.04e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 45.48  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  83 AQDEASALDTV-----------GAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVtealga 151
Cdd:PRK14951 347 APDEYAALTMVllrllafkpaaAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAA------ 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 152 aeapamagapkVAEAPREAETSRAAVPPGTVVPTEAA---APTEVTEGPGVAAPTKVAEAPGVASPTEA-----AEAPVP 223
Cdd:PRK14951 421 -----------APPAPVAAPAAAAPAAAPAAAPAAVAlapAPPAQAAPETVAIPVRVAPEPAVASAAPApaaapAAARLT 489
rne PRK10811
ribonuclease E; Reviewed
 72-247 2.14e-04

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 44.65  E-value: 2.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305   72 PTPVRAEAEDRAQDEASALDTVGAEAVAPAA-----SSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPpgVT 146
Cdd:PRK10811  848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAvepvvSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAP--VT 925

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  147 EALGAAEApamagapkvAEAPREAETSRAAVPPGTVVP-TEAAAPTEVTEGPGVAAPTKVAEAPGVA---SPTEAAEAPV 222
Cdd:PRK10811  926 EQPQVITE---------SDVAVAQEVAEHAEPVVEPQDeTADIEEAAETAEVVVAEPEVVAQPAAPVvaeVAAEVETVTA 996

                         170       180
                  ....*....|....*....|....*
gi 530433305  223 PATPTGAAAPTGAAESPGTSGSPRT 247
Cdd:PRK10811  997 VEPEVAPAQVPEATVEHNHATAPMT 1021
rne PRK10811
ribonuclease E; Reviewed
 71-221 2.35e-04

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 44.26  E-value: 2.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305   71 PPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPppgVTEAlg 150
Cdd:PRK10811  878 AVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEP---VVEP-- 952

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530433305  151 aaeapamagAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPgVAAPTKVAEAPGVASPTEA------AEAP 221
Cdd:PRK10811  953 ---------QDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAE-VETVTAVEPEVAPAQVPEAtvehnhATAP 1019
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 134-284 2.70e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 43.79  E-value: 2.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 134 AMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAET--SRAAVPPGTVvpteAAAPTEVTEGPG--VAAPTKVAEAP 209
Cdd:PTZ00436 203 AAAKKAAAPSGKKSAKAAAPAKAAAAPAKAAAPPAKAAAapAKAAAAPAKA----AAPPAKAAAPPAkaAAPPAKAAAPP 278

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530433305 210 GVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSA---AKKATPGAHTGAIPKATSATGAVPKGGGK 284
Cdd:PTZ00436 279 AKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAappAKAATPPAKAAAPPAKAAAAPVGKKAGGK 356
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
94-290 2.96e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.10  E-value: 2.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  94 GAEAVAPAASSAEAQSGAGSQAQEAdgAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETS 173
Cdd:PRK12323 370 GGAGPATAAAAPVAQPAPAAAAPAA--AAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 174 R--AAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVAS------PTEAAEAPVPATPTGAAAPTGAAESPGTSGSP 245
Cdd:PRK12323 448 PapAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPapadddPPPWEELPPEFASPAPAQPDAAPAGWVAESIP 527

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 530433305 246 RTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPKGGGKGVTRSR 290
Cdd:PRK12323 528 DPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASG 572
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 41-279 3.59e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 3.59e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  41 PKNRAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADG 120
Cdd:PRK07764 435 PAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRE 514

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 121 ------AGVG-------------PKAESVVG---------AAMASAIAPPPG---VTEALGAAEAPAMAGAPKVAEAPRE 169
Cdd:PRK07764 515 rwpeilAAVPkrsrktwaillpeATVLGVRGdtlvlgfstGGLARRFASPGNaevLVTALAEELGGDWQVEAVVGPAPGA 594

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 170 AETSRAAVPPGTVVPTEAAAPTEVT--EGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRT 247
Cdd:PRK07764 595 AGGEGPPAPASSGPPEEAARPAAPAapAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAG 674

                        250       260       270
                 ....*....|....*....|....*....|..
gi 530433305 248 AVVPgTSAAKKATPGAHTGAIPKATSATGAVP 279
Cdd:PRK07764 675 GAAP-AAPPPAPAPAAPAAPAGAAPAQPAPAP 705
PHA03247 PHA03247
large tegument protein UL36; Provisional
 71-280 3.91e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 3.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305   71 PPTPVRAEAEDRAQDEASALDTV----GAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAiAPPPGVT 146
Cdd:PHA03247 2702 PPPPPTPEPAPHALVSATPLPPGpaaaRQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA-APAAGPP 2780

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  147 EALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEA--------- 217
Cdd:PHA03247 2781 RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlggsvapgg 2860

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  218 -------AEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPK 280
Cdd:PHA03247 2861 dvrrrppSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQ 2930
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 9-243 5.65e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 5.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305   9 CVAAGIVIGAGAWYCVYKYTRGRDQTKKRMAKPkNRAVAGTGARARAGLRAGftiDLGSGFSPPTPVRAEAEDRAQDEAS 88
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAP-AAPAAPAAPAPAGAAAAP---AEASAAPAPGVAAPEHHPKHVAVPD 661

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  89 ALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAEsvvgAAMASAIAPPPGVTEALGAAEAPAmagapkvAEAPR 168
Cdd:PRK07764 662 ASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQP----APAPAATPPAGQADDPAAQPPQAA-------QGASA 730

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530433305 169 EAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSG 243
Cdd:PRK07764 731 PSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVA 805
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
51-222 9.03e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 9.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  51 ARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQE-ADGAGVGPKAES 129
Cdd:PRK12323 405 APAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPvAAAAAAAPARAA 484

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 130 VVGAAMASAIAPPPgvTEALGAAEAPAMAGAPKVAEAPREAETS--------RAAVPPGTVVPTEAAAPTEVTEGPGVAA 201
Cdd:PRK12323 485 PAAAPAPADDDPPP--WEELPPEFASPAPAQPDAAPAGWVAESIpdpatadpDDAFETLAPAPAAAPAPRAAAATEPVVA 562

                        170       180
                 ....*....|....*....|.
gi 530433305 202 PTKVAEAPGVASPTEAAEAPV 222
Cdd:PRK12323 563 PRPPRASASGLPDMFDGDWPA 583
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
44-242 1.04e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 1.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  44 RAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRA---EAEDRAQDEASALDTVGAEAVAPA-ASSAEAQSGAGSQAQEAD 119
Cdd:PRK12323 376 TAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAApaaAAAARAVAAAPARRSPAPEALAAArQASARGPGGAPAPAPAPA 455

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 120 GAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAetsrAAVPPGTVVPTEAAAPTEVTEGPGV 199
Cdd:PRK12323 456 AAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEF----ASPAPAQPDAAPAGWVAESIPDPAT 531

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 530433305 200 AAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTS 242
Cdd:PRK12323 532 ADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLP 574
VATPase_H cd00256
VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the ...
 388-455 1.68e-03

VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The topology is that of a superhelical spiral, in part the geometry is similar to superhelices composed of armadillo repeat motifs, as found in importins for example.


Pssm-ID: 238159 [Multi-domain]  Cd Length: 429  Bit Score: 41.23  E-value: 1.68e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530433305 388 LRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
Cdd:cd00256  355 LKILIHLLETSVDPIILAVACHDIGEYVRhYPRGKDVVEQLGGKQRVMRLLNHEDPNVRYEALLAVQKL 423
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 76-221 1.68e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 41.09  E-value: 1.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  76 RAEAEDRAQDEASALDTVGAEAVAPAAS-SAEAQSGAGSQAQEADGAGVGPKAESV-VGAAMASAIAPPPGVTEALGAAE 153
Cdd:PTZ00436 187 RARREDAAAAAAAKQKAAAKKAAAPSGKkSAKAAAPAKAAAAPAKAAAPPAKAAAApAKAAAAPAKAAAPPAKAAAPPAK 266

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530433305 154 APAMAGAPKVAEAPREAETSRAAVPPGTVvpteAAAPTEVTEGPG--VAAPTKVAEAPG--VASPTEAAEAP 221
Cdd:PTZ00436 267 AAAPPAKAAAPPAKAAAPPAKAAAPPAKA----AAAPAKAAAAPAkaAAAPAKAAAPPAkaAAPPAKAATPP 334
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 93-221 2.20e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 2.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  93 VGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPgvtealgaaeapaMAGAPKVAEAPREAET 172
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPA-------------PAPAPPSPAGNAPAGG 452

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 530433305 173 SRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAP 221
Cdd:PRK07764 453 APSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPA 501
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 420-456 2.33e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.87  E-value: 2.33e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 530433305   420 NQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLS 456
Cdd:smart00185   4 NKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
rne PRK10811
ribonuclease E; Reviewed
 100-279 2.60e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.18  E-value: 2.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  100 PAASSAEAQSGAGSQAQEADGAgvgPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagaPKVAEAP--REAETSRAAV 177
Cdd:PRK10811  846 PVVRPQDVQVEEQREAEEVQVQ---PVVAEVPVAAAVEPVVSAPVVEAV------------AEVVEEPvvVAEPQPEEVV 910

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  178 PPGTVVPTEAAAPteVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAK 257
Cdd:PRK10811  911 VVETTHPEVIAAP--VTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVA 988

                         170       180
                  ....*....|....*....|..
gi 530433305  258 KATPGAHTGAIPKATSATGAVP 279
Cdd:PRK10811  989 AEVETVTAVEPEVAPAQVPEAT 1010
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 47-220 3.14e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 40.35  E-value: 3.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  47 AGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRA--------QDEASALDTvGAEAVAPAASSAEAQSGAGSQAQEA 118
Cdd:PRK13108 275 APKGREAPGALRGSEYVVDEALEREPAELAAAAVASAasavgpvgPGEPNQPDD-VAEAVKAEVAEVTDEVAAESVVQVA 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 119 DGagVGPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagaPKVAEAPREAETSRAAvppgtvvPTEAAA-PTEVTEGP 197
Cdd:PRK13108 354 DR--DGESTPAVEETSEADIEREQPGDLAG------------QAPAAHQVDAEAASAA-------PEEPAAlASEAHDET 412

                        170       180
                 ....*....|....*....|...
gi 530433305 198 GVAAPTKVAEAPGVASPTEAAEA 220
Cdd:PRK13108 413 EPEVPEKAAPIPDPAKPDELAVA 435
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 136-262 3.18e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.47  E-value: 3.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 136 ASAIAPPPGVTEALGAAEAPAmagAPKVAEAPREAETSRAAVPPGTVVPTeAAAPTEVTEGPGVAAPTKVAEAPGVASPT 215
Cdd:PRK14951 368 AAAEAAAPAEKKTPARPEAAA---PAAAPVAQAAAAPAPAAAPAAAASAP-AAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 530433305 216 EAAEAPVPATPTGA-AAPTGAAESPGTSGSPRTAVVPGTSAAKKATPG 262
Cdd:PRK14951 444 AVALAPAPPAQAAPeTVAIPVRVAPEPAVASAAPAPAAAPAAARLTPT 491
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 168-279 3.18e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 3.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 168 REAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRT 247
Cdd:PRK07764 383 RRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAP 462

                         90       100       110
                 ....*....|....*....|....*....|..
gi 530433305 248 AVVPGTSAAKKATPGAHTGAIPKATSATGAVP 279
Cdd:PRK07764 463 SAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAP 494
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 40-189 5.51e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 39.70  E-value: 5.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  40 KPKNRAVAGTGARARAGLRAgftidlgsgfSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAeAQSGAGSQAQEAD 119
Cdd:PRK14951 365 KPAAAAEAAAPAEKKTPARP----------EAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAA-APPAPVAAPAAAA 433

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530433305 120 GAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTV----VPTEAAA 189
Cdd:PRK14951 434 PAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDVwhatVQQLAAA 507
PRK12727 PRK12727
flagellar biosynthesis protein FlhF;
71-224 7.01e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 237182 [Multi-domain]  Cd Length: 559  Bit Score: 39.59  E-value: 7.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  71 PPTPVRAEAEDRAQDEASALDTVgaeavapaASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASA----IAPPPGVT 146
Cdd:PRK12727  79 PAAPVHAPLKLSANANMSQRQRV--------ASAAEDMIAAMALRQPVSVPRQAPAAAPVRAASIPSPaaqaLAHAAAVR 150

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530433305 147 EALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTeAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPA 224
Cdd:PRK12727 151 TAPRQEHALSAVPEQLFADFLTTAPVPRAPVQAPVVAAP-APVPAIAAALAAHAAYAQDDDEQLDDDGFDLDDALPQI 227
KLF9_13_N-like cd21975
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ...
 164-290 8.54e-03

Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.


Pssm-ID: 409240 [Multi-domain]  Cd Length: 163  Bit Score: 37.36  E-value: 8.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 164 AEAPREAETSRAAVPPG----TVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESP 239
Cdd:cd21975   31 AAGLDVRATREVAKGPGppgpAWKPDGADSPGLVTAAPHLLAANVLAPLRGPSVEGSSLESGDADMGSDSDVAPASGAAA 110

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 530433305 240 GTSgsprtavvPGTSAAKKATPGAHTGAIPKATSATGAVPKGGGKGVTRSR 290
Cdd:cd21975  111 STS--------PESSSDAASSPSPLSLLHPGEAGLEPERPRPRVRRGVRRR 153
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
70-214 9.34e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 39.06  E-value: 9.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  70 SPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASS----AEAQSGAGSQAQEADGAGVGPKAESVvGAAMASAIAPPPGV 145
Cdd:PRK07003 483 DAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASredaPAAAAPPAPEARPPTPAAAAPAARAG-GAAAALDVLRNAGM 561

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530433305 146 TeaLGAAEAPAMAGAPKVAEAPREAETSrAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASP 214
Cdd:PRK07003 562 R--VSSDRGARAAAAAKPAAAPAAAPKP-AAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPP 627
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 82-263 9.66e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 38.81  E-value: 9.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305  82 RAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPkAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAP 161
Cdd:PRK13108 277 KGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGP-GEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADR 355

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530433305 162 KVAEAPREAETSRAAVppgtvvptEAAAPTEvTEGPGVAAPtKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGT 241
Cdd:PRK13108 356 DGESTPAVEETSEADI--------EREQPGD-LAGQAPAAH-QVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPD 425

                        170       180
                 ....*....|....*....|..
gi 530433305 242 SGSPRTAVVPGTSAAKKATPGA 263
Cdd:PRK13108 426 PAKPDELAVAGPGDDPAEPDGI 447
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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