|
Name |
Accession |
Description |
Interval |
E-value |
| GcvT |
COG0404 |
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ... |
454-852 |
1.07e-85 |
|
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage
:
Pssm-ID: 440173 [Multi-domain] Cd Length: 372 Bit Score: 278.50 E-value: 1.07e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 454 GRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVppdkdllaleqsktfykpdwfDIVESEVKCCKEAVCVIDMSSFTKFE 533
Cdd:COG0404 1 FRPLRRTPLHDRHVALGAKFVDFGGWEMPVQYP---------------------GGVIAEHLAVREAVGLFDVSHMGKIE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 534 ITstGDQALEVLQYLFSNDLDV-PVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWAWLKKHMPKDSNL 612
Cdd:COG0404 60 VT--GPDAAAFLDRLVTNDVSKlKPGRARYTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEEHLPPDFDV 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 613 LLEDVTWKYTALNLIGPRAVDVLSELsyAPMTPDHFPSLFCKEMSVGYANgIRVMSMTHTGEPGFMLYIPIEYALHVYNE 692
Cdd:COG0404 138 TITDVTDDWALLAVQGPKAREVLAKL--TDADLSALPFMSFREGTVAGVP-VRVSRTGYTGEDGFEIYVPAEDAEALWDA 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 693 VMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGmDFIGRDALLQQKQNGVYKRLTMFIL 772
Cdd:COG0404 215 LLEAGEEFGVKPCGLGARDTLRLEAGYPLYGHELDETTTPLEAGLGWAVKLDKG-DFIGKEALLRQKEEGPRRKLVGLEL 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 773 DDHDSdldlwPWWGEPIYRNGQYVGKTTSSAYSYSLERHVCLGFVHNFSEDTGEeqvvtadfinrgEYEIDIAGYRFQAK 852
Cdd:COG0404 294 DGRGV-----PRAGAPVLADGEVVGEVTSGTFSPTLGKSIALAYVPAGLARPGT------------ELEVEIRGKRVPAE 356
|
|
| DadA |
COG0665 |
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]; |
41-419 |
4.15e-73 |
|
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
:
Pssm-ID: 440429 [Multi-domain] Cd Length: 364 Bit Score: 244.43 E-value: 4.15e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 41 TQAQVVICGGGITGTSVAYHLSKMGWkDIVLLEQGRLAAGSTRFCAGILST---ARHLTIEQKMADYSNKLYYQLEQETG 117
Cdd:COG0665 1 ATADVVVIGGGIAGLSTAYHLARRGL-DVTVLERGRPGSGASGRNAGQLRPglaALADRALVRLAREALDLWRELAAELG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 118 IQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDAVVSSADVALALAS 197
Cdd:COG0665 80 IDCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 198 AASQNGVQIYDRTSVLHVMVKKGQVTGVETDKGQIECQYFVNCAGQWAYELGlsNEEPVSIPLHACEHFYLLTRPLETPL 277
Cdd:COG0665 160 AARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLL--PMLGLRLPLRPVRGYVLVTEPLPDLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 278 qssTPTIVDaDGRIYIRNWQGG--ILSGGFEKNPkpiftegknqleiQNLQEDWDHFEPLLSSLLRRMPELETLEIMKLV 355
Cdd:COG0665 238 ---LRPVLD-DTGVYLRPTADGrlLVGGTAEPAG-------------FDRAPTPERLEALLRRLRRLFPALADAEIVRAW 300
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530424043 356 NCPETFTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKR 419
Cdd:COG0665 301 AGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
|
|
| FAO_M |
pfam16350 |
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ... |
405-460 |
6.85e-16 |
|
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).
:
Pssm-ID: 465100 Cd Length: 56 Bit Score: 72.49 E-value: 6.85e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 530424043 405 HGYPSENVWELDLKRFGALQSSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTS 460
Cdd:pfam16350 1 DGEPPIDLWECDIRRFGPHQNNREYLRERVAENYGEVYDIHHPNEEREAGRPLRTS 56
|
|
| NADB_Rossmann super family |
cl21454 |
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ... |
5-74 |
5.35e-03 |
|
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.
The actual alignment was detected with superfamily member PTZ00383:
Pssm-ID: 473865 [Multi-domain] Cd Length: 497 Bit Score: 40.11 E-value: 5.35e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530424043 5 RLLSIVGRQRASPGWQNWSSARNSTSAAEARSMALPTQAQ-----VVICGGGITGTSVAYHLSKM-GWKDIVLLEQ 74
Cdd:PTZ00383 3 RIKSSFSRYRSSTLNSNAVKEASRDTSNQSLNTSSGNRLGsdvydVVIVGGGVTGTALFYTLSKFtNLKKIALIER 78
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| GcvT |
COG0404 |
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ... |
454-852 |
1.07e-85 |
|
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage
Pssm-ID: 440173 [Multi-domain] Cd Length: 372 Bit Score: 278.50 E-value: 1.07e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 454 GRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVppdkdllaleqsktfykpdwfDIVESEVKCCKEAVCVIDMSSFTKFE 533
Cdd:COG0404 1 FRPLRRTPLHDRHVALGAKFVDFGGWEMPVQYP---------------------GGVIAEHLAVREAVGLFDVSHMGKIE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 534 ITstGDQALEVLQYLFSNDLDV-PVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWAWLKKHMPKDSNL 612
Cdd:COG0404 60 VT--GPDAAAFLDRLVTNDVSKlKPGRARYTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEEHLPPDFDV 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 613 LLEDVTWKYTALNLIGPRAVDVLSELsyAPMTPDHFPSLFCKEMSVGYANgIRVMSMTHTGEPGFMLYIPIEYALHVYNE 692
Cdd:COG0404 138 TITDVTDDWALLAVQGPKAREVLAKL--TDADLSALPFMSFREGTVAGVP-VRVSRTGYTGEDGFEIYVPAEDAEALWDA 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 693 VMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGmDFIGRDALLQQKQNGVYKRLTMFIL 772
Cdd:COG0404 215 LLEAGEEFGVKPCGLGARDTLRLEAGYPLYGHELDETTTPLEAGLGWAVKLDKG-DFIGKEALLRQKEEGPRRKLVGLEL 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 773 DDHDSdldlwPWWGEPIYRNGQYVGKTTSSAYSYSLERHVCLGFVHNFSEDTGEeqvvtadfinrgEYEIDIAGYRFQAK 852
Cdd:COG0404 294 DGRGV-----PRAGAPVLADGEVVGEVTSGTFSPTLGKSIALAYVPAGLARPGT------------ELEVEIRGKRVPAE 356
|
|
| GCV_T |
pfam01571 |
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ... |
463-736 |
5.44e-84 |
|
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.
Pssm-ID: 460255 Cd Length: 254 Bit Score: 269.46 E-value: 5.44e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 463 YDRLDAQGARWMEKHGFERPKYFVPPDKDllaleqsktfykpdwfdiveSEVKCCKEAVCVIDMSSFTKFEITstGDQAL 542
Cdd:pfam01571 1 YDRHVALGAKFVEFAGWEMPVQYGSNGIL--------------------AEHRAVREAAGLFDVSHMGKIEVS--GPDAA 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 543 EVLQYLFSNDLD-VPVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWAWLKKHMPKDsNLLLEDVTWKY 621
Cdd:pfam01571 59 AFLQRLTTNDVSkLKPGRATYTLMLNERGGVIDDLTVYRLGDDHFLLVVNAANREKDLAWLRKHAEKL-DVVVVDVTDDY 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 622 TALNLIGPRAVDVLSELSYAPMTPDhFPSLFCKEMSVGYANgIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYG 701
Cdd:pfam01571 138 ALLALQGPKAREVLEKLTDGDLLEA-LPFFSFREIEIGGVP-VRVSRTGYTGEDGFEIYVPAEDAVELWEALLEAGAELG 215
|
250 260 270
....*....|....*....|....*....|....*
gi 530424043 702 IRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECG 736
Cdd:pfam01571 216 LRPAGLGARDSLRLEAGLPLYGHDLDEETTPLEAG 250
|
|
| DadA |
COG0665 |
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]; |
41-419 |
4.15e-73 |
|
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
Pssm-ID: 440429 [Multi-domain] Cd Length: 364 Bit Score: 244.43 E-value: 4.15e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 41 TQAQVVICGGGITGTSVAYHLSKMGWkDIVLLEQGRLAAGSTRFCAGILST---ARHLTIEQKMADYSNKLYYQLEQETG 117
Cdd:COG0665 1 ATADVVVIGGGIAGLSTAYHLARRGL-DVTVLERGRPGSGASGRNAGQLRPglaALADRALVRLAREALDLWRELAAELG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 118 IQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDAVVSSADVALALAS 197
Cdd:COG0665 80 IDCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 198 AASQNGVQIYDRTSVLHVMVKKGQVTGVETDKGQIECQYFVNCAGQWAYELGlsNEEPVSIPLHACEHFYLLTRPLETPL 277
Cdd:COG0665 160 AARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLL--PMLGLRLPLRPVRGYVLVTEPLPDLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 278 qssTPTIVDaDGRIYIRNWQGG--ILSGGFEKNPkpiftegknqleiQNLQEDWDHFEPLLSSLLRRMPELETLEIMKLV 355
Cdd:COG0665 238 ---LRPVLD-DTGVYLRPTADGrlLVGGTAEPAG-------------FDRAPTPERLEALLRRLRRLFPALADAEIVRAW 300
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530424043 356 NCPETFTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKR 419
Cdd:COG0665 301 AGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
|
|
| DAO |
pfam01266 |
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ... |
45-402 |
3.03e-55 |
|
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.
Pssm-ID: 426168 [Multi-domain] Cd Length: 339 Bit Score: 194.54 E-value: 3.03e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 45 VVICGGGITGTSVAYHLSKMGWkDIVLLEQG-RLAAGSTRFCAGILSTARHLTIEQ---KMADYSNKLYYQLEQETGIQT 120
Cdd:pfam01266 2 VVVIGGGIVGLSTAYELARRGL-SVTLLERGdDPGSGASGRNAGLIHPGLRYLEPSelaRLALEALDLWEELEEELGIDC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 121 GYTRTGSIFLAQTQDRlISLKRINAGLNVIGIPSEIISPKKVAELHHLLNvhDLVGAMHVPEDAVVSSADVALALASAAS 200
Cdd:pfam01266 81 GFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEPLLP--GLRGGLFYPDGGHVDPARLLRALARAAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 201 QNGVQIYDRTSVLHVmVKKGQVTGVETDkGQIECqyFVNCAGQWAYELGLSneePVSIPLHACEHFYLLTRPL-ETPLQS 279
Cdd:pfam01266 158 ALGVRIIEGTEVTGI-EEEGGVWGVVTT-GEADA--VVNAAGAWADLLALP---GLRLPVRPVRGQVLVLEPLpEALLIL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 280 STPTIVDADGRIYIRN-WQGGILSGGFEknpkpiFTEGKNQLEIqnlqeDWDHFEPLLSSLLRRMPELETLEimklvncp 358
Cdd:pfam01266 231 PVPITVDPGRGVYLRPrADGRLLLGGTD------EEDGFDDPTP-----DPEEIEELLEAARRLFPALADIE-------- 291
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 530424043 359 ETF-----TPDMRCIMGEsPAVQGYFVLAGMNSAGLSFGGGAGKYLAEW 402
Cdd:pfam01266 292 RAWaglrpLPDGLPIIGR-PGSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
|
|
| gcvT |
PRK00389 |
glycine cleavage system aminomethyltransferase GcvT; |
457-838 |
5.85e-38 |
|
glycine cleavage system aminomethyltransferase GcvT;
Pssm-ID: 234742 [Multi-domain] Cd Length: 359 Bit Score: 145.64 E-value: 5.85e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 457 LRTSPLYDRLDAQGARWMEKHGFERP-KYfvppdkdllaleQSktfykpdwfdIVEsEVKCCKEAVCVIDMSSFTKFEIT 535
Cdd:PRK00389 2 LKRTPLYDLHVALGAKMVDFGGWEMPvQY------------GS----------IIE-EHHAVRTDAGLFDVSHMGEVDVT 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 536 stGDQALEVLQYLFSNDLD-VPVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMI--SPTDQQVhcWAWLKKHMpKDSNL 612
Cdd:PRK00389 59 --GPDALAFLQYLLANDVSkLKPGKAQYTCMLNEDGGVIDDLIVYKLSEDEYLLVvnAANREKD--LAWIKSHA-AGFGV 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 613 LLEDVTWKYTALNLIGPRAVDVLSELSYAPMtpDHFPSLFCKEMSVGYANGIRVmSMT-HTGEPGFMLYIPIEYALHVYN 691
Cdd:PRK00389 134 EVTDRSDDLAMIAVQGPKAREKLQKLTDADL--SELKPFFGAQGAEVGGGDVLV-ARTgYTGEDGFEIYLPAEDAEALWD 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 692 EVMSVGqkygIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGMDFIGRDALLQQKQNGVYKRLTMF- 770
Cdd:PRK00389 211 ALLEAG----VKPCGLGARDTLRLEAGMPLYGQDMDETITPLEAGLGWTVKLEEKRDFIGREALEAQKEAGVERKLVGLe 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 771 -----IlddhdsdldlwPWWGEPIYRNGQYVGKTTSSAYSYSLERHVCLGFVhnfSEDTGEE------------QVVTAD 833
Cdd:PRK00389 287 leergI-----------PRHGYPVLADGEEIGEVTSGTFSPTLGKSIALAYV---PAGVGDEveveirgkqvpaKVVKPP 352
|
....*
gi 530424043 834 FINRG 838
Cdd:PRK00389 353 FVRRG 357
|
|
| FAO_M |
pfam16350 |
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ... |
405-460 |
6.85e-16 |
|
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).
Pssm-ID: 465100 Cd Length: 56 Bit Score: 72.49 E-value: 6.85e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 530424043 405 HGYPSENVWELDLKRFGALQSSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTS 460
Cdd:pfam16350 1 DGEPPIDLWECDIRRFGPHQNNREYLRERVAENYGEVYDIHHPNEEREAGRPLRTS 56
|
|
| soxA_mon |
TIGR01377 |
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ... |
45-420 |
1.78e-12 |
|
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]
Pssm-ID: 130444 [Multi-domain] Cd Length: 380 Bit Score: 69.86 E-value: 1.78e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 45 VVICGGGITGTSVAYHLSKMGwKDIVLLEQGRL--AAGSTRfcaGILSTARHLTIEQ---KMADYSNKLYYQLEQETGIQ 119
Cdd:TIGR01377 3 VIVVGAGIMGCFAAYHLAKHG-KKTLLLEQFDLphSRGSSH---GQSRIIRKAYPEDfytPMMLECYQLWAQLEKEAGTK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 120 TgYTRTGSIFLAQTQDRliSLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDAVVSSADVALALASAA 199
Cdd:TIGR01377 79 L-HRQTGLLLLGPKENQ--FLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRALQELA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 200 SQNGVQIYDRTSVLHVMVKKGQVTgVETDKGQIECQYFVNCAGQWAYEL--GLSNEEPVSiPLHACEHFYLLTRPLETPL 277
Cdd:TIGR01377 156 EAHGATVRDGTKVVEIEPTELLVT-VKTTKGSYQANKLVVTAGAWTSKLlsPLGIEIPLQ-PLRINVCYWREKEPGSYGV 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 278 QSSTPTIV--DADGRIYirnwqgGILSGGFEKNPKPIFTEGKN----------QLEIQNLQEdwdhfeplLSSLLR-RMP 344
Cdd:TIGR01377 234 SQAFPCFLvlGLNPHIY------GLPSFEYPGLMKVYYHHGQQidpderdcpfGADIEDVQI--------LRKFVRdHLP 299
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530424043 345 EL-ETLEIMKLvnCPETFTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRF 420
Cdd:TIGR01377 300 GLnGEPKKGEV--CMYTNTPDEHFVIDLHPKYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRF 374
|
|
| PRK00711 |
PRK00711 |
D-amino acid dehydrogenase; |
44-293 |
7.57e-05 |
|
D-amino acid dehydrogenase;
Pssm-ID: 234819 [Multi-domain] Cd Length: 416 Bit Score: 45.95 E-value: 7.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 44 QVVICGGGITGTSVAYHLSKMGWKDIVLLEQGRLA-------AG--STRFCA-----GILSTA------RH--------L 95
Cdd:PRK00711 2 RVVVLGSGVIGVTSAWYLAQAGHEVTVIDRQPGPAletsfanAGqiSPGYAApwaapGVPLKAikwlfqRHaplairpdG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 96 TIEQ-----KM-------------------ADYSNKLYYQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIG 151
Cdd:PRK00711 82 DPFQlrwmwQMlrnctasryavnksrmvrlAEYSRDCLKALRAETGIQYEGRQGGTLQLFRTQQQLDAAAKDIAVLEEAG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 152 IPSEIISPKKVAELH-HLLNV-HDLVGAMHVPEDAV-------VSSADvalalasAASQNGVQIYDRTSVLHVMVKKGQV 222
Cdd:PRK00711 162 VPYELLDRDELAAVEpALAGVrHKLVGGLRLPNDETgdcqlftQRLAA-------MAEQLGVKFRFNTPVDGLLVEGGRI 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530424043 223 TGVETDKGQIECQYFVNCAGQWAYEL--GLSNEEPVsIPLHAcehfYLLTRPLETPLQSSTPTIVDADGRIYI 293
Cdd:PRK00711 235 TGVQTGGGVITADAYVVALGSYSTALlkPLGVDIPV-YPLKG----YSLTVPITDEDRAPVSTVLDETYKIAI 302
|
|
| PTZ00383 |
PTZ00383 |
malate:quinone oxidoreductase; Provisional |
5-74 |
5.35e-03 |
|
malate:quinone oxidoreductase; Provisional
Pssm-ID: 240393 [Multi-domain] Cd Length: 497 Bit Score: 40.11 E-value: 5.35e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530424043 5 RLLSIVGRQRASPGWQNWSSARNSTSAAEARSMALPTQAQ-----VVICGGGITGTSVAYHLSKM-GWKDIVLLEQ 74
Cdd:PTZ00383 3 RIKSSFSRYRSSTLNSNAVKEASRDTSNQSLNTSSGNRLGsdvydVVIVGGGVTGTALFYTLSKFtNLKKIALIER 78
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| GcvT |
COG0404 |
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ... |
454-852 |
1.07e-85 |
|
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage
Pssm-ID: 440173 [Multi-domain] Cd Length: 372 Bit Score: 278.50 E-value: 1.07e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 454 GRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVppdkdllaleqsktfykpdwfDIVESEVKCCKEAVCVIDMSSFTKFE 533
Cdd:COG0404 1 FRPLRRTPLHDRHVALGAKFVDFGGWEMPVQYP---------------------GGVIAEHLAVREAVGLFDVSHMGKIE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 534 ITstGDQALEVLQYLFSNDLDV-PVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWAWLKKHMPKDSNL 612
Cdd:COG0404 60 VT--GPDAAAFLDRLVTNDVSKlKPGRARYTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEEHLPPDFDV 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 613 LLEDVTWKYTALNLIGPRAVDVLSELsyAPMTPDHFPSLFCKEMSVGYANgIRVMSMTHTGEPGFMLYIPIEYALHVYNE 692
Cdd:COG0404 138 TITDVTDDWALLAVQGPKAREVLAKL--TDADLSALPFMSFREGTVAGVP-VRVSRTGYTGEDGFEIYVPAEDAEALWDA 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 693 VMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGmDFIGRDALLQQKQNGVYKRLTMFIL 772
Cdd:COG0404 215 LLEAGEEFGVKPCGLGARDTLRLEAGYPLYGHELDETTTPLEAGLGWAVKLDKG-DFIGKEALLRQKEEGPRRKLVGLEL 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 773 DDHDSdldlwPWWGEPIYRNGQYVGKTTSSAYSYSLERHVCLGFVHNFSEDTGEeqvvtadfinrgEYEIDIAGYRFQAK 852
Cdd:COG0404 294 DGRGV-----PRAGAPVLADGEVVGEVTSGTFSPTLGKSIALAYVPAGLARPGT------------ELEVEIRGKRVPAE 356
|
|
| GCV_T |
pfam01571 |
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ... |
463-736 |
5.44e-84 |
|
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.
Pssm-ID: 460255 Cd Length: 254 Bit Score: 269.46 E-value: 5.44e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 463 YDRLDAQGARWMEKHGFERPKYFVPPDKDllaleqsktfykpdwfdiveSEVKCCKEAVCVIDMSSFTKFEITstGDQAL 542
Cdd:pfam01571 1 YDRHVALGAKFVEFAGWEMPVQYGSNGIL--------------------AEHRAVREAAGLFDVSHMGKIEVS--GPDAA 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 543 EVLQYLFSNDLD-VPVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMISPTDQQVHCWAWLKKHMPKDsNLLLEDVTWKY 621
Cdd:pfam01571 59 AFLQRLTTNDVSkLKPGRATYTLMLNERGGVIDDLTVYRLGDDHFLLVVNAANREKDLAWLRKHAEKL-DVVVVDVTDDY 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 622 TALNLIGPRAVDVLSELSYAPMTPDhFPSLFCKEMSVGYANgIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYG 701
Cdd:pfam01571 138 ALLALQGPKAREVLEKLTDGDLLEA-LPFFSFREIEIGGVP-VRVSRTGYTGEDGFEIYVPAEDAVELWEALLEAGAELG 215
|
250 260 270
....*....|....*....|....*....|....*
gi 530424043 702 IRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECG 736
Cdd:pfam01571 216 LRPAGLGARDSLRLEAGLPLYGHDLDEETTPLEAG 250
|
|
| DadA |
COG0665 |
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]; |
41-419 |
4.15e-73 |
|
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
Pssm-ID: 440429 [Multi-domain] Cd Length: 364 Bit Score: 244.43 E-value: 4.15e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 41 TQAQVVICGGGITGTSVAYHLSKMGWkDIVLLEQGRLAAGSTRFCAGILST---ARHLTIEQKMADYSNKLYYQLEQETG 117
Cdd:COG0665 1 ATADVVVIGGGIAGLSTAYHLARRGL-DVTVLERGRPGSGASGRNAGQLRPglaALADRALVRLAREALDLWRELAAELG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 118 IQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDAVVSSADVALALAS 197
Cdd:COG0665 80 IDCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 198 AASQNGVQIYDRTSVLHVMVKKGQVTGVETDKGQIECQYFVNCAGQWAYELGlsNEEPVSIPLHACEHFYLLTRPLETPL 277
Cdd:COG0665 160 AARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLL--PMLGLRLPLRPVRGYVLVTEPLPDLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 278 qssTPTIVDaDGRIYIRNWQGG--ILSGGFEKNPkpiftegknqleiQNLQEDWDHFEPLLSSLLRRMPELETLEIMKLV 355
Cdd:COG0665 238 ---LRPVLD-DTGVYLRPTADGrlLVGGTAEPAG-------------FDRAPTPERLEALLRRLRRLFPALADAEIVRAW 300
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530424043 356 NCPETFTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKR 419
Cdd:COG0665 301 AGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
|
|
| DAO |
pfam01266 |
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ... |
45-402 |
3.03e-55 |
|
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.
Pssm-ID: 426168 [Multi-domain] Cd Length: 339 Bit Score: 194.54 E-value: 3.03e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 45 VVICGGGITGTSVAYHLSKMGWkDIVLLEQG-RLAAGSTRFCAGILSTARHLTIEQ---KMADYSNKLYYQLEQETGIQT 120
Cdd:pfam01266 2 VVVIGGGIVGLSTAYELARRGL-SVTLLERGdDPGSGASGRNAGLIHPGLRYLEPSelaRLALEALDLWEELEEELGIDC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 121 GYTRTGSIFLAQTQDRlISLKRINAGLNVIGIPSEIISPKKVAELHHLLNvhDLVGAMHVPEDAVVSSADVALALASAAS 200
Cdd:pfam01266 81 GFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEPLLP--GLRGGLFYPDGGHVDPARLLRALARAAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 201 QNGVQIYDRTSVLHVmVKKGQVTGVETDkGQIECqyFVNCAGQWAYELGLSneePVSIPLHACEHFYLLTRPL-ETPLQS 279
Cdd:pfam01266 158 ALGVRIIEGTEVTGI-EEEGGVWGVVTT-GEADA--VVNAAGAWADLLALP---GLRLPVRPVRGQVLVLEPLpEALLIL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 280 STPTIVDADGRIYIRN-WQGGILSGGFEknpkpiFTEGKNQLEIqnlqeDWDHFEPLLSSLLRRMPELETLEimklvncp 358
Cdd:pfam01266 231 PVPITVDPGRGVYLRPrADGRLLLGGTD------EEDGFDDPTP-----DPEEIEELLEAARRLFPALADIE-------- 291
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 530424043 359 ETF-----TPDMRCIMGEsPAVQGYFVLAGMNSAGLSFGGGAGKYLAEW 402
Cdd:pfam01266 292 RAWaglrpLPDGLPIIGR-PGSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
|
|
| gcvT |
PRK00389 |
glycine cleavage system aminomethyltransferase GcvT; |
457-838 |
5.85e-38 |
|
glycine cleavage system aminomethyltransferase GcvT;
Pssm-ID: 234742 [Multi-domain] Cd Length: 359 Bit Score: 145.64 E-value: 5.85e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 457 LRTSPLYDRLDAQGARWMEKHGFERP-KYfvppdkdllaleQSktfykpdwfdIVEsEVKCCKEAVCVIDMSSFTKFEIT 535
Cdd:PRK00389 2 LKRTPLYDLHVALGAKMVDFGGWEMPvQY------------GS----------IIE-EHHAVRTDAGLFDVSHMGEVDVT 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 536 stGDQALEVLQYLFSNDLD-VPVGHIVHTGMLNEGGGYENDCSIARLNKRSFFMI--SPTDQQVhcWAWLKKHMpKDSNL 612
Cdd:PRK00389 59 --GPDALAFLQYLLANDVSkLKPGKAQYTCMLNEDGGVIDDLIVYKLSEDEYLLVvnAANREKD--LAWIKSHA-AGFGV 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 613 LLEDVTWKYTALNLIGPRAVDVLSELSYAPMtpDHFPSLFCKEMSVGYANGIRVmSMT-HTGEPGFMLYIPIEYALHVYN 691
Cdd:PRK00389 134 EVTDRSDDLAMIAVQGPKAREKLQKLTDADL--SELKPFFGAQGAEVGGGDVLV-ARTgYTGEDGFEIYLPAEDAEALWD 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 692 EVMSVGqkygIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGMDFIGRDALLQQKQNGVYKRLTMF- 770
Cdd:PRK00389 211 ALLEAG----VKPCGLGARDTLRLEAGMPLYGQDMDETITPLEAGLGWTVKLEEKRDFIGREALEAQKEAGVERKLVGLe 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 771 -----IlddhdsdldlwPWWGEPIYRNGQYVGKTTSSAYSYSLERHVCLGFVhnfSEDTGEE------------QVVTAD 833
Cdd:PRK00389 287 leergI-----------PRHGYPVLADGEEIGEVTSGTFSPTLGKSIALAYV---PAGVGDEveveirgkqvpaKVVKPP 352
|
....*
gi 530424043 834 FINRG 838
Cdd:PRK00389 353 FVRRG 357
|
|
| LhgO |
COG0579 |
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism]; |
45-245 |
6.77e-21 |
|
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
Pssm-ID: 440344 [Multi-domain] Cd Length: 418 Bit Score: 96.37 E-value: 6.77e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 45 VVICGGGITGTSVAYHLSK-MGWKdIVLLEQ-GRLAAGSTRFCAGILstarH--L-----TIEQKMADYSNKLYYQLEQE 115
Cdd:COG0579 7 VVIIGAGIVGLALARELSRyEDLK-VLVLEKeDDVAQESSGNNSGVI----HagLyytpgSLKARLCVEGNELFYELCRE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 116 TGIQtgYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPS-EIISPKKVAELHHLLNvHDLVGAMHVPEDAVVSSADVALA 194
Cdd:COG0579 82 LGIP--FKRCGKLVVATGEEEVAFLEKLYERGKANGVPGlEILDREELRELEPLLS-DEGVAALYSPSTGIVDPGALTRA 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 530424043 195 LASAASQNGVQIYDRTSVLHVMVKKGQVTgVETDKGQIECQYFVNCAGQWA 245
Cdd:COG0579 159 LAENAEANGVELLLNTEVTGIEREGDGWE-VTTNGGTIRARFVINAAGLYA 208
|
|
| FAO_M |
pfam16350 |
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ... |
405-460 |
6.85e-16 |
|
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).
Pssm-ID: 465100 Cd Length: 56 Bit Score: 72.49 E-value: 6.85e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 530424043 405 HGYPSENVWELDLKRFGALQSSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTS 460
Cdd:pfam16350 1 DGEPPIDLWECDIRRFGPHQNNREYLRERVAENYGEVYDIHHPNEEREAGRPLRTS 56
|
|
| dmdA |
PRK12486 |
dimethylsulfoniopropionate demethylase; |
455-839 |
1.09e-14 |
|
dimethylsulfoniopropionate demethylase;
Pssm-ID: 237113 [Multi-domain] Cd Length: 368 Bit Score: 76.71 E-value: 1.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 455 RQLRTSPLYDRLDAQGARwmekhGFerpkyfvppdkdllaleqskTFYK----PDWFDIVESEVKCCKEAVCVIDMSSFT 530
Cdd:PRK12486 9 RRLRRTPFSDGVEAAGVK-----AY--------------------TVYNhmllPTVFESVEDDYAHLKEHVQVWDVAVER 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 531 KFEITstGDQALEVLQYLFSNDLD-VPVGHIVHTGMLNEGGGYENDCSIARLNKRSFFmISPTDQQVHCWAwlkKHMPKD 609
Cdd:PRK12486 64 QVEIR--GPDAARLVQMLTPRDLRgMKPGQCYYVPIVDETGGMLNDPVALKLAEDRWW-ISIADSDLLLWV---KGLANG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 610 SNLLLEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFpslfckeMSVGYAN--GIRvMSMTHTG---EPGFMLYIP-I 683
Cdd:PRK12486 138 RKLDVLVVEPDVSPLAVQGPKADALMARVFGEAIRDLRF-------FRFGYFDfeGTD-LVIARSGyskQGGFEIYVEgS 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 684 EYALHVYNEVMSVGQKYGIRnAGYYALRSlRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGMDFIGRDALLQQKQNGV 763
Cdd:PRK12486 210 DLGMPLWDALFEAGKDLNVR-AGCPNLIE-RIEGGLLSYGNDMTRDNTPHECGLGRFCNTQTDIGCIGKDALLRVAKEGP 287
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530424043 764 YKRLTMFILDDHDSDLDLWPWwgePIYRNGQYVGKTTSSAYSYSLERHVCLGFVHNFSEDTGEE-QVVTADFINRGE 839
Cdd:PRK12486 288 QKQIRGIKIGGERIPPCDRAW---PLLAGDNRVGQVTSAAYSPDFQTNVAIGMVRMTHWDPGTGlEVETPDGMRPAT 361
|
|
| PLN02319 |
PLN02319 |
aminomethyltransferase |
563-817 |
5.05e-13 |
|
aminomethyltransferase
Pssm-ID: 177953 [Multi-domain] Cd Length: 404 Bit Score: 72.06 E-value: 5.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 563 TGML----NEGGGYENDCSIARLNKRSFFMI-----SPTDQqvhcwAWLKKHMpKDSNLLLEDVTW----KYTALNLIGP 629
Cdd:PLN02319 112 TGTLsvftNEKGGIIDDTVITKVTDDHIYLVvnagcRDKDL-----AHIEEHM-KAFKAKGGDVSWhvhdERSLLALQGP 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 630 RAVDVLSELSYAPMTPDHFpSLFcKEMSVgyaNGI--RVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKyGIRNAGY 707
Cdd:PLN02319 186 LAAPVLQHLTKEDLSKMYF-GDF-RITDI---NGAdcFLTRTGYTGEDGFEISVPSEHAVDLAKALLEKSEG-KVRLTGL 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 708 YALRSLRIEKFFAFWGQDINNLTTPLECGRE----SRVKlEKGmDFIGRDALLQQKQNGVYKRLTMFILDdhdsdldlwp 783
Cdd:PLN02319 260 GARDSLRLEAGLCLYGNDLEEHITPVEAGLAwtigKRRR-AEG-GFLGADVILKQLKEGVSRRRVGFISS---------- 327
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 530424043 784 wwGEP------IY-RNGQYVGKTTSSAYSYSLERHVCLGFV 817
Cdd:PLN02319 328 --GAParshseILdESGEKIGEVTSGGFSPCLKKNIAMGYV 366
|
|
| soxA_mon |
TIGR01377 |
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ... |
45-420 |
1.78e-12 |
|
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]
Pssm-ID: 130444 [Multi-domain] Cd Length: 380 Bit Score: 69.86 E-value: 1.78e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 45 VVICGGGITGTSVAYHLSKMGwKDIVLLEQGRL--AAGSTRfcaGILSTARHLTIEQ---KMADYSNKLYYQLEQETGIQ 119
Cdd:TIGR01377 3 VIVVGAGIMGCFAAYHLAKHG-KKTLLLEQFDLphSRGSSH---GQSRIIRKAYPEDfytPMMLECYQLWAQLEKEAGTK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 120 TgYTRTGSIFLAQTQDRliSLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDAVVSSADVALALASAA 199
Cdd:TIGR01377 79 L-HRQTGLLLLGPKENQ--FLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRALQELA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 200 SQNGVQIYDRTSVLHVMVKKGQVTgVETDKGQIECQYFVNCAGQWAYEL--GLSNEEPVSiPLHACEHFYLLTRPLETPL 277
Cdd:TIGR01377 156 EAHGATVRDGTKVVEIEPTELLVT-VKTTKGSYQANKLVVTAGAWTSKLlsPLGIEIPLQ-PLRINVCYWREKEPGSYGV 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 278 QSSTPTIV--DADGRIYirnwqgGILSGGFEKNPKPIFTEGKN----------QLEIQNLQEdwdhfeplLSSLLR-RMP 344
Cdd:TIGR01377 234 SQAFPCFLvlGLNPHIY------GLPSFEYPGLMKVYYHHGQQidpderdcpfGADIEDVQI--------LRKFVRdHLP 299
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530424043 345 EL-ETLEIMKLvnCPETFTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRF 420
Cdd:TIGR01377 300 GLnGEPKKGEV--CMYTNTPDEHFVIDLHPKYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRF 374
|
|
| GCV_T_C |
pfam08669 |
Glycine cleavage T-protein C-terminal barrel domain; This is a family of glycine cleavage ... |
786-852 |
6.20e-11 |
|
Glycine cleavage T-protein C-terminal barrel domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.
Pssm-ID: 462554 [Multi-domain] Cd Length: 80 Bit Score: 59.03 E-value: 6.20e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530424043 786 GEPIYRNGQYVGKTTSSAYSYSLERHVCLGFVHnfsedtgeeqvvtADFINRG-EYEIDIAGYRFQAK 852
Cdd:pfam08669 18 GEPVLRDGEVVGYVTSGAYSPTLGKSIALAYVD-------------AELAKPGtEVEVEIRGKRVPAT 72
|
|
| gcvT |
PRK13579 |
glycine cleavage system aminomethyltransferase GcvT; |
534-817 |
2.95e-09 |
|
glycine cleavage system aminomethyltransferase GcvT;
Pssm-ID: 237435 [Multi-domain] Cd Length: 370 Bit Score: 59.96 E-value: 2.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 534 ITSTGDQALEVLQYLFSND-LDVPVGHIVHTGMLNEGGGYENDCSIARLNKRsFFMISPTDQQVHCWAWLKKHMPKDSNL 612
Cdd:PRK13579 63 IEVSGKDAAAALERLVPVDiLALKEGRQRYTFFTNEQGGILDDLMVTNLGDH-LFLVVNAACKDADIAHLREHLSDECEV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 613 -LLEDvtwkYTALNLIGPRAVDVLSELSyapmtPDHFPSLFckeMSVGyanGIRVMSMT-------HTGEPGFMLYIPIE 684
Cdd:PRK13579 142 nPLDD----RALLALQGPEAEAVLADLG-----PPVAALRF---MDGF---EPRLHGVDcfvsrsgYTGEDGFEISVPAD 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 685 YA------LHVYNEVMSVGqkYGIRNagyyalrSLRIEKFFAFWGQDINNLTTPLECGRE---SRVKLEKGmDFIGRDAL 755
Cdd:PRK13579 207 AAealaeaLLADPRVEPIG--LGARD-------SLRLEAGLCLYGHDIDTTTTPVEAALEwaiQKARREAG-GFPGAKAI 276
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530424043 756 LQQKQNGV-YKRLTMFILDDHDSDLdlwpwwGEPIYRN-GQYVGKTTSSAYSYSLERHVCLGFV 817
Cdd:PRK13579 277 LAALAKGAsRRRVGLKPEGRAPVRE------GAPLFDDaGTEIGTVTSGGFGPSVGGPVAMGYV 334
|
|
| PRK00711 |
PRK00711 |
D-amino acid dehydrogenase; |
44-293 |
7.57e-05 |
|
D-amino acid dehydrogenase;
Pssm-ID: 234819 [Multi-domain] Cd Length: 416 Bit Score: 45.95 E-value: 7.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 44 QVVICGGGITGTSVAYHLSKMGWKDIVLLEQGRLA-------AG--STRFCA-----GILSTA------RH--------L 95
Cdd:PRK00711 2 RVVVLGSGVIGVTSAWYLAQAGHEVTVIDRQPGPAletsfanAGqiSPGYAApwaapGVPLKAikwlfqRHaplairpdG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 96 TIEQ-----KM-------------------ADYSNKLYYQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIG 151
Cdd:PRK00711 82 DPFQlrwmwQMlrnctasryavnksrmvrlAEYSRDCLKALRAETGIQYEGRQGGTLQLFRTQQQLDAAAKDIAVLEEAG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 152 IPSEIISPKKVAELH-HLLNV-HDLVGAMHVPEDAV-------VSSADvalalasAASQNGVQIYDRTSVLHVMVKKGQV 222
Cdd:PRK00711 162 VPYELLDRDELAAVEpALAGVrHKLVGGLRLPNDETgdcqlftQRLAA-------MAEQLGVKFRFNTPVDGLLVEGGRI 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530424043 223 TGVETDKGQIECQYFVNCAGQWAYEL--GLSNEEPVsIPLHAcehfYLLTRPLETPLQSSTPTIVDADGRIYI 293
Cdd:PRK00711 235 TGVQTGGGVITADAYVVALGSYSTALlkPLGVDIPV-YPLKG----YSLTVPITDEDRAPVSTVLDETYKIAI 302
|
|
| PRK11728 |
PRK11728 |
L-2-hydroxyglutarate oxidase; |
45-242 |
1.10e-04 |
|
L-2-hydroxyglutarate oxidase;
Pssm-ID: 183292 [Multi-domain] Cd Length: 393 Bit Score: 45.58 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 45 VVICGGGITGTSVAYHLSK-MGWKDIVLLE-QGRLAA------------------GS--TRFC-AGilstarhltieqkm 101
Cdd:PRK11728 5 FVIIGGGIVGLSTAMQLQErYPGARIAVLEkESGPARhqtghnsgvihagvyytpGSlkARFCrRG-------------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 102 adysNKLYYQLEQETGIqtGYTRTGSIFLAQTQDRLISLKRI--NAGLNviGIPSEIISPKKVAELHHllNVHDLvGAMH 179
Cdd:PRK11728 71 ----NEATKAFCDQHGI--PYEECGKLLVATSELELERMEALyeRARAN--GIEVERLDAEELREREP--NIRGL-GAIF 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530424043 180 VPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVMVKKGQVTgVETDKGQIECQYFVNCAG 242
Cdd:PRK11728 140 VPSTGIVDYRAVAEAMAELIQARGGEIRLGAEVTALDEHANGVV-VRTTQGEYEARTLINCAG 201
|
|
| solA |
PRK11259 |
N-methyl-L-tryptophan oxidase; |
45-422 |
1.23e-04 |
|
N-methyl-L-tryptophan oxidase;
Pssm-ID: 236887 [Multi-domain] Cd Length: 376 Bit Score: 45.21 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 45 VVICGGGITGTSVAYHLSKMGwKDIVLLEQGRL--AAGS----TRfcagILstaRHLTIEQkmADY------SNKLYYQL 112
Cdd:PRK11259 6 VIVIGLGSMGSAAGYYLARRG-LRVLGLDRFMPphQQGSshgdTR----II---RHAYGEG--PAYvplvlrAQELWREL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 113 EQETGiQTGYTRTGSIFLAQTQDRLISlkrinaglNVI------GIPSEIISPKKVAELHHLLNVHDlvGAMHV------ 180
Cdd:PRK11259 76 ERESG-EPLFVRTGVLNLGPADSDFLA--------NSIrsarqhGLPHEVLDAAEIRRRFPQFRLPD--GYIALfepdgg 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 181 ---PEDAVVSSADVALalasaasQNGVQIYDRTSVLHVMVKKGQVTgVETDKGQIECQYFVNCAGQWAYELgLSneePVS 257
Cdd:PRK11259 145 flrPELAIKAHLRLAR-------EAGAELLFNEPVTAIEADGDGVT-VTTADGTYEAKKLVVSAGAWVKDL-LP---PLE 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 258 IPLHACEH-FYLLTRPLETPLQSSTPtivdadgrIYIRNWQGGILSGGFEKNPKPIFTEGKNQ--LEIQNLQE-----DW 329
Cdd:PRK11259 213 LPLTPVRQvLAWFQADGRYSEPNRFP--------AFIWEVPDGDQYYGFPAENGPGLKIGKHNggQEITSPDErdrfvTV 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530424043 330 DHFEPLLSSLLRR-MPELETLeiMKLVNCPETFTPDMRCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYP 408
Cdd:PRK11259 285 AEDGAELRPFLRNyLPGVGPC--LRGAACTYTNTPDEHFIIDTLPGHPNVLVASGCSGHGFKFASVLGEILADLAQDGTS 362
|
410
....*....|....
gi 530424043 409 SENVWELDLKRFGA 422
Cdd:PRK11259 363 DFDLSPFSLSRFAA 376
|
|
| HemY |
COG1232 |
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ... |
45-75 |
1.50e-03 |
|
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis
Pssm-ID: 440845 [Multi-domain] Cd Length: 443 Bit Score: 42.13 E-value: 1.50e-03
10 20 30
....*....|....*....|....*....|.
gi 530424043 45 VVICGGGITGTSVAYHLSKMGwKDIVLLEQG 75
Cdd:COG1232 4 VAVIGGGIAGLTAAYRLAKAG-HEVTVLEAS 33
|
|
| PTZ00383 |
PTZ00383 |
malate:quinone oxidoreductase; Provisional |
5-74 |
5.35e-03 |
|
malate:quinone oxidoreductase; Provisional
Pssm-ID: 240393 [Multi-domain] Cd Length: 497 Bit Score: 40.11 E-value: 5.35e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530424043 5 RLLSIVGRQRASPGWQNWSSARNSTSAAEARSMALPTQAQ-----VVICGGGITGTSVAYHLSKM-GWKDIVLLEQ 74
Cdd:PTZ00383 3 RIKSSFSRYRSSTLNSNAVKEASRDTSNQSLNTSSGNRLGsdvydVVIVGGGVTGTALFYTLSKFtNLKKIALIER 78
|
|
| PRK12409 |
PRK12409 |
D-amino acid dehydrogenase small subunit; Provisional |
44-87 |
8.39e-03 |
|
D-amino acid dehydrogenase small subunit; Provisional
Pssm-ID: 237093 [Multi-domain] Cd Length: 410 Bit Score: 39.62 E-value: 8.39e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 530424043 44 QVVICGGGITGTSVAYHLSKMGWkDIVLLEQGRLAAGSTRFCAG 87
Cdd:PRK12409 3 HIAVIGAGITGVTTAYALAQRGY-QVTVFDRHRYAAMETSFANG 45
|
|
| |
