NCBI Conserved Domain Search

Conserved domains on [gi|530374626|ref|XP_005247515|]

View

muscleblind-like protein 1 isoform X1 [Homo sapiens]

Protein Classification

zinc finger CCCH domain-containing protein( domain architecture ID 10646956)

zinc finger CCCH domain-containing protein similar to Homo sapiens Muscleblind-like proteins

CATH: 4.10.1000.10

Gene Ontology: GO:0046872|GO:0003676

PubMed: 12665246|27990022

SCOP: 3001741

Graphical summary

Zoom to residue level

show extra options »

Show site features Horizontal zoom: ×

List of domain hits

Name

Accession

Description

Interval

E-value

ZnF_C3H1

smart00356

zinc finger;

212-236

5.38e-05

zinc finger;

Pssm-ID: 214632 [Multi-domain] Cd Length: 27 Bit Score: 39.92 E-value: 5.38e-05

                           10        20
                   ....*....|....*....|....*
gi 530374626   212 RLEVCREYQRGNCNRGENdCRFAHP 236
Cdd:smart00356   3 KTELCKFFKRGYCPRGDR-CKFAHP 26

Name

Accession

Description

Interval

E-value

ZnF_C3H1

smart00356

zinc finger;

212-236

5.38e-05

zinc finger;

Pssm-ID: 214632 [Multi-domain] Cd Length: 27 Bit Score: 39.92 E-value: 5.38e-05

                           10        20
                   ....*....|....*....|....*
gi 530374626   212 RLEVCREYQRGNCNRGENdCRFAHP 236
Cdd:smart00356   3 KTELCKFFKRGYCPRGDR-CKFAHP 26

zf_CCCH_4

pfam18345

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...

216-235

1.58e-03

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.

Pssm-ID: 465719 [Multi-domain] Cd Length: 19 Bit Score: 35.47 E-value: 1.58e-03

                          10        20
                  ....*....|....*....|
gi 530374626  216 CREYQRGNCNRGENdCRFAH 235
Cdd:pfam18345   1 CKFFLKGRCRYGDK-CRFAH 19

Name

Accession

Description

Interval

E-value

ZnF_C3H1

smart00356

zinc finger;

212-236

5.38e-05

zinc finger;

Pssm-ID: 214632 [Multi-domain] Cd Length: 27 Bit Score: 39.92 E-value: 5.38e-05

                           10        20
                   ....*....|....*....|....*
gi 530374626   212 RLEVCREYQRGNCNRGENdCRFAHP 236
Cdd:smart00356   3 KTELCKFFKRGYCPRGDR-CKFAHP 26

zf_CCCH_4

pfam18345

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...

216-235

1.58e-03

Pssm-ID: 465719 [Multi-domain] Cd Length: 19 Bit Score: 35.47 E-value: 1.58e-03

                          10        20
                  ....*....|....*....|
gi 530374626  216 CREYQRGNCNRGENdCRFAH 235
Cdd:pfam18345   1 CKFFLKGRCRYGDK-CRFAH 19

zf-CCCH

pfam00642

Zinc finger C-x8-C-x5-C-x3-H type (and similar);

214-236

5.25e-03

Zinc finger C-x8-C-x5-C-x3-H type (and similar);

Pssm-ID: 459885 [Multi-domain] Cd Length: 27 Bit Score: 34.48 E-value: 5.25e-03

                          10        20
                  ....*....|....*....|....
gi 530374626  214 EVCREYQR-GNCNRGENdCRFAHP 236
Cdd:pfam00642   4 ELCRFFLRtGYCKYGDR-CKFAHG 26

zf-CCCH_4

pfam18044

CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and ...

215-236

7.98e-03

CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and one histidine to coordinate the zinc ion. This domain is found in a wide variety of proteins such as E3 ligases.

Pssm-ID: 465626 Cd Length: 22 Bit Score: 33.72 E-value: 7.98e-03

                          10        20
                  ....*....|....*....|..
gi 530374626  215 VCREYQRGNCNRGENdCRFAHP 236
Cdd:pfam18044   2 LCRYFQKGGCRYGDN-CRFSHD 22

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01