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Conserved domains on  [gi|522078119|ref|WP_020589328|]
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cell division topological specificity factor MinE [Desulfobacter curvatus]

Protein Classification

cell division topological specificity factor MinE( domain architecture ID 10510225)

cell division topological specificity factor MinE prevents cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites, ensuring cell division at the proper site

CATH:  3.30.1070.10
Gene Ontology:  GO:0051301
PubMed:  9393861|11062554
SCOP:  4001444

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MinE COG0851
Septum formation topological specificity factor MinE [Cell cycle control, cell division, ...
 4-85 2.71e-23

Septum formation topological specificity factor MinE [Cell cycle control, cell division, chromosome partitioning];


:

Pssm-ID: 440612  Cd Length: 84  Bit Score: 84.39  E-value: 2.71e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522078119  4 EFLRRFTGQKRSS-DEAKKRLQFSLVYDKLEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVKNDKDVSALVFNTPILH 82
Cdd:COG0851   2 SLLDFFRGRKKSSaDVAKERLQLVLAHDRAGLSPDYLEQLKKEILEVISKYVEIDEDAVEVSLEREDDLSALEANIPLPR 81


                ...
gi 522078119 83 VKR 85
Cdd:COG0851  82 VKR 84
 
Name Accession Description Interval E-value
MinE COG0851
Septum formation topological specificity factor MinE [Cell cycle control, cell division, ...
 4-85 2.71e-23

Septum formation topological specificity factor MinE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440612  Cd Length: 84  Bit Score: 84.39  E-value: 2.71e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522078119  4 EFLRRFTGQKRSS-DEAKKRLQFSLVYDKLEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVKNDKDVSALVFNTPILH 82
Cdd:COG0851   2 SLLDFFRGRKKSSaDVAKERLQLVLAHDRAGLSPDYLEQLKKEILEVISKYVEIDEDAVEVSLEREDDLSALEANIPLPR 81


                ...
gi 522078119 83 VKR 85
Cdd:COG0851  82 VKR 84
MinE pfam03776
Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to ...
 15-80 1.30e-18

Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to code for three gene products (MinC, MinD, and MinE) whose coordinate action is required for proper placement of the division septum. The minE gene codes for a topological specificity factor that, in wild-type cells, prevents the division inhibitor from acting at internal division sites while permitting it to block septation at polar sites.


Pssm-ID: 461046  Cd Length: 67  Bit Score: 72.03  E-value: 1.30e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 522078119  15 SSDEAKKRLQFSLVYDKLEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVKNDK-DVSALVFNTPI 80
Cdd:pfam03776  1 SANVAKERLQLILAHDRADLSPDYLEQLKNEILEVISKYVEIDEEKVEVQLEQDDgDVSVLEANIPL 67
PRK13988 PRK13988
cell division topological specificity factor MinE; Provisional
 1-86 3.74e-16

cell division topological specificity factor MinE; Provisional


Pssm-ID: 184441  Cd Length: 97  Bit Score: 66.71  E-value: 3.74e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522078119  1 MLQEFLRR-FTGQKRSSDEAKKRLQFSLVYDKLEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVKNDKDVSALVFNTP 79
Cdd:PRK13988  2 TLRDLLEKlFGRQPASASTARERLQLVLAHDRADLSPELLEQMRKEILEVVARYVEIDPEEGEVSLETEDRMTALVANLP 81


                ....*..
gi 522078119 80 ILHVKRK 86
Cdd:PRK13988 82 IRRVKRG 88
minE TIGR01215
cell division topological specificity factor MinE; This protein is involved in the process of ...
 4-80 4.88e-12

cell division topological specificity factor MinE; This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division]


Pssm-ID: 188120  Cd Length: 81  Bit Score: 55.83  E-value: 4.88e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 522078119   4 EFLRRFTGQKRSSDE-AKKRLQFSLVYDKLEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVKNDKDVSALVFNTPI 80
Cdd:TIGR01215  2 SLLEFFKSRKKNSAEvAKDRLKLILAHERAQLAPEYLEELRKEILEVISKYVEIDPEMVEVSLESQGDMSVLELNITL 79
 
Name Accession Description Interval E-value
MinE COG0851
Septum formation topological specificity factor MinE [Cell cycle control, cell division, ...
 4-85 2.71e-23

Septum formation topological specificity factor MinE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440612  Cd Length: 84  Bit Score: 84.39  E-value: 2.71e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522078119  4 EFLRRFTGQKRSS-DEAKKRLQFSLVYDKLEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVKNDKDVSALVFNTPILH 82
Cdd:COG0851   2 SLLDFFRGRKKSSaDVAKERLQLVLAHDRAGLSPDYLEQLKKEILEVISKYVEIDEDAVEVSLEREDDLSALEANIPLPR 81


                ...
gi 522078119 83 VKR 85
Cdd:COG0851  82 VKR 84
MinE pfam03776
Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to ...
 15-80 1.30e-18

Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to code for three gene products (MinC, MinD, and MinE) whose coordinate action is required for proper placement of the division septum. The minE gene codes for a topological specificity factor that, in wild-type cells, prevents the division inhibitor from acting at internal division sites while permitting it to block septation at polar sites.


Pssm-ID: 461046  Cd Length: 67  Bit Score: 72.03  E-value: 1.30e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 522078119  15 SSDEAKKRLQFSLVYDKLEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVKNDK-DVSALVFNTPI 80
Cdd:pfam03776  1 SANVAKERLQLILAHDRADLSPDYLEQLKNEILEVISKYVEIDEEKVEVQLEQDDgDVSVLEANIPL 67
PRK13988 PRK13988
cell division topological specificity factor MinE; Provisional
 1-86 3.74e-16

cell division topological specificity factor MinE; Provisional


Pssm-ID: 184441  Cd Length: 97  Bit Score: 66.71  E-value: 3.74e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522078119  1 MLQEFLRR-FTGQKRSSDEAKKRLQFSLVYDKLEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVKNDKDVSALVFNTP 79
Cdd:PRK13988  2 TLRDLLEKlFGRQPASASTARERLQLVLAHDRADLSPELLEQMRKEILEVVARYVEIDPEEGEVSLETEDRMTALVANLP 81


                ....*..
gi 522078119 80 ILHVKRK 86
Cdd:PRK13988 82 IRRVKRG 88
PRK13987 PRK13987
cell division topological specificity factor MinE; Provisional
 5-86 1.14e-15

cell division topological specificity factor MinE; Provisional


Pssm-ID: 237579  Cd Length: 91  Bit Score: 65.46  E-value: 1.14e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522078119  5 FLRRFTGQKRSSDEAKKRLQFSLVYDKLEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVK-----NDKDVSALVFNTP 79
Cdd:PRK13987  3 LFKFFSKKPTSKDVAKERLKLILIHDRGDISPDVLEMIKEDILKVISKYVEIDNEDVDIKMTkseeiDEGMSPALIANIP 82


                ....*..
gi 522078119 80 ILHVKRK 86
Cdd:PRK13987 83 IKKIKKK 89
minE TIGR01215
cell division topological specificity factor MinE; This protein is involved in the process of ...
 4-80 4.88e-12

cell division topological specificity factor MinE; This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division]


Pssm-ID: 188120  Cd Length: 81  Bit Score: 55.83  E-value: 4.88e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 522078119   4 EFLRRFTGQKRSSDE-AKKRLQFSLVYDKLEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVKNDKDVSALVFNTPI 80
Cdd:TIGR01215  2 SLLEFFKSRKKNSAEvAKDRLKLILAHERAQLAPEYLEELRKEILEVISKYVEIDPEMVEVSLESQGDMSVLELNITL 79
minE PRK00296
cell division topological specificity factor MinE; Reviewed
 5-74 4.82e-07

cell division topological specificity factor MinE; Reviewed


Pssm-ID: 234718  Cd Length: 86  Bit Score: 43.30  E-value: 4.82e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 522078119  5 FLRRFTGQKRSSDE-AKKRLQFSLVYDK-LEVNDTTLTDLQTDIVNVISKYFEIDQDALELKVKNDKDVSAL 74
Cdd:PRK00296  3 LLDFFRSRKKSTANvAKERLQIIVAHERsSRGEPDYLPQLRKEILEVIAKYVQIDPDKVSVQLDKDGDISTL 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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