NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform 3 [Homo sapiens]
Protein Classification
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9( domain architecture ID 14448744)
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NDUFB9) is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| Complex1_LYR_NDUFB9_LYRM3 | cd20263 | LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta ... |
1-45 | 1.31e-20 | ||
LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NDUFB9) and similar proteins; NDUFB9, also called LYR motif-containing protein 3 (LYRM3), or Complex I-B22 (CI-B22), or NADH-ubiquinone oxidoreductase B22 subunit (UQOR22), is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I), and is believed to be not involved in catalysis. In general, accessory subunits are integral for assembly and function of Complex I, which functions in the transfer of electrons from NADH to the respiratory chain. NDUFB9 belongs to the Complex1_LYR-like superfamily that consists of proteins of diverse functions that are exclusively found in eukaryotes and contain the conserved tripeptide 'LYR' close to the N-terminus. : Pssm-ID: 380758 Cd Length: 77 Bit Score: 79.53 E-value: 1.31e-20
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| Name | Accession | Description | Interval | E-value | ||
| Complex1_LYR_NDUFB9_LYRM3 | cd20263 | LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta ... |
1-45 | 1.31e-20 | ||
LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NDUFB9) and similar proteins; NDUFB9, also called LYR motif-containing protein 3 (LYRM3), or Complex I-B22 (CI-B22), or NADH-ubiquinone oxidoreductase B22 subunit (UQOR22), is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I), and is believed to be not involved in catalysis. In general, accessory subunits are integral for assembly and function of Complex I, which functions in the transfer of electrons from NADH to the respiratory chain. NDUFB9 belongs to the Complex1_LYR-like superfamily that consists of proteins of diverse functions that are exclusively found in eukaryotes and contain the conserved tripeptide 'LYR' close to the N-terminus. Pssm-ID: 380758 Cd Length: 77 Bit Score: 79.53 E-value: 1.31e-20
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| Complex1_LYR | pfam05347 | Complex 1 protein (LYR family); Proteins in this family include an accessory subunit of the ... |
2-29 | 2.38e-04 | ||
Complex 1 protein (LYR family); Proteins in this family include an accessory subunit of the higher eukaryotic NADH dehydrogenase complex. In Saccharomyces cerevisiae, the Isd11 protein has been shown to play a role in Fe/S cluster biogenesis in mitochondria. We have named this family LYR after a highly conserved tripeptide motif close to the N-terminus of these proteins. Pssm-ID: 428432 Cd Length: 59 Bit Score: 36.79 E-value: 2.38e-04
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| Name | Accession | Description | Interval | E-value | ||
| Complex1_LYR_NDUFB9_LYRM3 | cd20263 | LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta ... |
1-45 | 1.31e-20 | ||
LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NDUFB9) and similar proteins; NDUFB9, also called LYR motif-containing protein 3 (LYRM3), or Complex I-B22 (CI-B22), or NADH-ubiquinone oxidoreductase B22 subunit (UQOR22), is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I), and is believed to be not involved in catalysis. In general, accessory subunits are integral for assembly and function of Complex I, which functions in the transfer of electrons from NADH to the respiratory chain. NDUFB9 belongs to the Complex1_LYR-like superfamily that consists of proteins of diverse functions that are exclusively found in eukaryotes and contain the conserved tripeptide 'LYR' close to the N-terminus. Pssm-ID: 380758 Cd Length: 77 Bit Score: 79.53 E-value: 1.31e-20
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| Complex1_LYR | pfam05347 | Complex 1 protein (LYR family); Proteins in this family include an accessory subunit of the ... |
2-29 | 2.38e-04 | ||
Complex 1 protein (LYR family); Proteins in this family include an accessory subunit of the higher eukaryotic NADH dehydrogenase complex. In Saccharomyces cerevisiae, the Isd11 protein has been shown to play a role in Fe/S cluster biogenesis in mitochondria. We have named this family LYR after a highly conserved tripeptide motif close to the N-terminus of these proteins. Pssm-ID: 428432 Cd Length: 59 Bit Score: 36.79 E-value: 2.38e-04
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| Complex1_LYR_SF | cd20251 | LYR (leucine-tyrosine-arginine) motif found in Complex1_LYR-like superfamily; The ... |
1-30 | 6.10e-04 | ||
LYR (leucine-tyrosine-arginine) motif found in Complex1_LYR-like superfamily; The Complex1_LYR-like superfamily consists of proteins of diverse functions that are exclusively found in eukaryotes and contain the conserved tripeptide 'LYR' close to the N-terminus. The human genome has at least ten LYR proteins that were predominantly identified as mitochondrial proteins. Some family members were also found in the cytosol or nucleus. LYR motif-containing protein 4 (LYRM4) represents the only LYR protein that is directly involved in the first steps of Fe-S cluster generation. Other LYR proteins have been identified as accessory subunits or assembly factors of mitochondrial OXPHOS (oxidative phosphorylation) complexes I, II, III and V, and they play specific roles in acetate metabolism. Pssm-ID: 380755 Cd Length: 57 Bit Score: 35.60 E-value: 6.10e-04
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| Complex1_LYR_LYRM7 | cd20267 | LYR (leucine-tyrosine-arginine) motif found in LYR motif-containing protein 7 (LYRM7) and ... |
1-26 | 3.94e-03 | ||
LYR (leucine-tyrosine-arginine) motif found in LYR motif-containing protein 7 (LYRM7) and similar proteins; LYRM7 is an assembly factor required for Rieske iron sulfur (Fe-S) protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. It functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. LYRM7 mutations cause a multifocal cavitating leukoencephalopathy with a distinct and recognizable magnetic resonance imaging (MRI) pattern. LYRM7 belongs to the Complex1_LYR-like superfamily that consists of proteins of diverse functions that are exclusively found in eukaryotes and contain the conserved tripeptide 'LYR' close to the N-terminus. Pssm-ID: 380762 Cd Length: 72 Bit Score: 34.08 E-value: 3.94e-03
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| Complex1_LYR_LYRM4 | cd20264 | LYR (leucine-tyrosine-arginine) motif found in LYR motif-containing protein 4 (LYRM4) and ... |
2-27 | 6.35e-03 | ||
LYR (leucine-tyrosine-arginine) motif found in LYR motif-containing protein 4 (LYRM4) and similar proteins; LYRM4, also called ISD11, is a eukaryote-specific component of the mitochondrial biogenesis of Fe-S clusters which are essential cofactors in multiple processes, including oxidative phosphorylation. It is required for nuclear and mitochondrial iron-sulfur protein biosynthesis by forming a complex with, and stabilizing, the sulfur donor NFS1. LYRM4 belongs to the Complex1_LYR-like superfamily that consists of proteins of diverse functions that are exclusively found in eukaryotes and contain the conserved tripeptide 'LYR' close to the N-terminus. Pssm-ID: 380759 Cd Length: 69 Bit Score: 33.26 E-value: 6.35e-03
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