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Conserved domains on  [gi|51948478|ref|NP_001004252|]
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phenylalanine--tRNA ligase beta subunit [Rattus norvegicus]

Protein Classification

phenylalanine--tRNA ligase beta subunit( domain architecture ID 1004798)

phenylalanine--tRNA ligase beta subunit is involved in the process of aminoacylation which attaching an amino acid to a tRNA

CATH:  3.30.56.10
EC:  6.1.1.20
Gene Ontology:  GO:0005524|GO:0046872|GO:0004826|GO:0003723

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02265 super family cl33446
probable phenylalanyl-tRNA synthetase beta chain
 1-589 0e+00

probable phenylalanyl-tRNA synthetase beta chain


The actual alignment was detected with superfamily member PLN02265:

Pssm-ID: 215149 [Multi-domain]  Cd Length: 597  Bit Score: 898.27  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478    1 MPTVSVKRDLLFQVLGRTYTDEEFDELCFEFGLELDEITSEKQIISKEQG----NVKAQGASDVVLYKIDVPANRYDLLC 76
Cdd:PLN02265   1 MPTVSVGRDRLFAALGRTYTQEEFDELCFEFGIELDDVTTEKAIIRKEKHldeeEDGGADDDEEVIYKIDVPANRYDLLC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   77 LEGLARGLQVFKERIKAPVYK-RVMPKGEIQKLIITEETAKVRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRA 155
Cdd:PLN02265  81 LEGLARALRVFLGTEPIPTYRlAEISKGSILKMHVKPETSLIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRT 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  156 LVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDNHLKHYLHIIESKPLYPVIYDSNGVVLSMPP 235
Cdd:PLN02265 161 LVAIGTHDLDTLQGPFTYEALPPEDINFVPLKQTKSFRADELMEFYKSDMKLKKFLHIIENSPVFPVIYDSNRTVLSLPP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  236 IINGNHSKITVNTRNIFIECTGTDLTKAKIVLDIIVTMFSEYCENQFTVEAAEVVSPSGKSSTLPELPYRKEMVRADLIN 315
Cdd:PLN02265 241 IINGAHSAITLDTKNVFIECTATDLTKAKIVLNTMVTMFSEYCARKFEVEPVEVVYPDGKSTVYPDLSVRTMEVDLSYIN 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  316 KKVGIKETPANLAKLLTRMCLKSEVIG-DGNQIEVEIPPTRADVIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLN 394
Cdd:PLN02265 321 SSIGVSLDAEEVASLLNKMQLQAEQSSdDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSMTVGKQQPLN 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  395 KLTELLRLDMAAAGFTEALTFALCSQEDIADKLGLNISATKAVHIGNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKL 474
Cdd:PLN02265 401 QFSDLLRAEVAMAGFTEVLTWILCSHKENFAMLNREDDGNSAVIIGNPRSADFEVVRTSLLPGLLKTLGHNKDAPKPIKL 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  475 FEISDIVVQDPSKDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPPGE--ESGGYVIKASAGSAFFPGRCAEIF 552
Cdd:PLN02265 481 FEVSDVVLLDESKDVGARNSRRLAALYCGTTSGFEVIHGLVDRIMEVLGIPFVEigDNNGYYVEPSNEPEYFPGRQASII 560

                        570       580       590
                 ....*....|....*....|....*....|....*..
gi 51948478  553 VGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:PLN02265 561 YKGKHVGTFGIVHPEVLNNFDIPDPCSFLELDLEPLL 597
 
Name Accession Description Interval E-value
PLN02265 PLN02265
probable phenylalanyl-tRNA synthetase beta chain
 1-589 0e+00

probable phenylalanyl-tRNA synthetase beta chain


Pssm-ID: 215149 [Multi-domain]  Cd Length: 597  Bit Score: 898.27  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478    1 MPTVSVKRDLLFQVLGRTYTDEEFDELCFEFGLELDEITSEKQIISKEQG----NVKAQGASDVVLYKIDVPANRYDLLC 76
Cdd:PLN02265   1 MPTVSVGRDRLFAALGRTYTQEEFDELCFEFGIELDDVTTEKAIIRKEKHldeeEDGGADDDEEVIYKIDVPANRYDLLC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   77 LEGLARGLQVFKERIKAPVYK-RVMPKGEIQKLIITEETAKVRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRA 155
Cdd:PLN02265  81 LEGLARALRVFLGTEPIPTYRlAEISKGSILKMHVKPETSLIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRT 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  156 LVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDNHLKHYLHIIESKPLYPVIYDSNGVVLSMPP 235
Cdd:PLN02265 161 LVAIGTHDLDTLQGPFTYEALPPEDINFVPLKQTKSFRADELMEFYKSDMKLKKFLHIIENSPVFPVIYDSNRTVLSLPP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  236 IINGNHSKITVNTRNIFIECTGTDLTKAKIVLDIIVTMFSEYCENQFTVEAAEVVSPSGKSSTLPELPYRKEMVRADLIN 315
Cdd:PLN02265 241 IINGAHSAITLDTKNVFIECTATDLTKAKIVLNTMVTMFSEYCARKFEVEPVEVVYPDGKSTVYPDLSVRTMEVDLSYIN 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  316 KKVGIKETPANLAKLLTRMCLKSEVIG-DGNQIEVEIPPTRADVIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLN 394
Cdd:PLN02265 321 SSIGVSLDAEEVASLLNKMQLQAEQSSdDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSMTVGKQQPLN 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  395 KLTELLRLDMAAAGFTEALTFALCSQEDIADKLGLNISATKAVHIGNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKL 474
Cdd:PLN02265 401 QFSDLLRAEVAMAGFTEVLTWILCSHKENFAMLNREDDGNSAVIIGNPRSADFEVVRTSLLPGLLKTLGHNKDAPKPIKL 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  475 FEISDIVVQDPSKDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPPGE--ESGGYVIKASAGSAFFPGRCAEIF 552
Cdd:PLN02265 481 FEVSDVVLLDESKDVGARNSRRLAALYCGTTSGFEVIHGLVDRIMEVLGIPFVEigDNNGYYVEPSNEPEYFPGRQASII 560

                        570       580       590
                 ....*....|....*....|....*....|....*..
gi 51948478  553 VGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:PLN02265 561 YKGKHVGTFGIVHPEVLNNFDIPDPCSFLELDLEPLL 597
pheT_arch TIGR00471
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA ...
 1-589 3.51e-166

phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from eukaryotic cytosol, the Archaea, and spirochetes. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 273096 [Multi-domain]  Cd Length: 551  Bit Score: 484.64  E-value: 3.51e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478     1 MPTVSVKRDLLFQVLgrtyTDEEFDELCFEFGLELDEITSekqiISKEQGNVKaqgasdvvlykIDVPANRYDLLCLEGL 80
Cdd:TIGR00471   1 MPTVTVYKDDLEDLL----IGTDRDEILEELPMMGDEIEG----FDEESPEIK-----------VEFNPNRPDLLSVEGL 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478    81 ARGLQVFKERIKAPVYKRVMPKGeiQKLIITEETAKVRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRALVAIG 160
Cdd:TIGR00471  62 ARSLRGYLGIEKGLKSYDSKKGD--VKLTVDESVLQIRPFITGAVVKGIILNDKVLESLIELQEKLHWNIGRNRRKVAIG 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   161 THDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDnhlKHYLHIIESKPLYPVIYDSNGVVLSMPPIINGN 240
Cdd:TIGR00471 140 IHDLDKVEFPFHYKAVSPNGIKFVPLNSDQEMTPDEILEEHPKG---IRYAHIIEDSDKFPLILDSKDDVLSMPPIINSE 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   241 HSKITVNTRNIFIECTGTDLTKAKIVLDIIVTMFSEYCENQFTVEaaEVVSPSGkSSTLPELPYRKEMVRADLINKKVGI 320
Cdd:TIGR00471 217 LTKLTVNTRNLLIDVTGTDKTAVEITLNIACTMFADRGDGRITVV--EVERPDE-HLGQPNLAPRFMEVSVEYINSLLGL 293

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   321 KETPANLAKLLTRMCLKSEVigDGNQIEVEIPPTRADVIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLNKLTELL 400
Cdd:TIGR00471 294 NLSADEIAHSLKKMRLDAVQ--SDEKLKVVIPAYRVDILHEVDIIEDVAIGYGYNNFPPELPLINTIGRLKPLNKVSDII 371

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   401 RLDMAAAGFTEALTFALCSQEDIADKlgLNISATKAVHIGNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKLFEISDI 480
Cdd:TIGR00471 372 REIMVGLGFQEVIPLTLTSEEVNFKR--MRIEDNNDVKVANPKTLEYTIVRTSLLPGLLETLSENKHHELPQKIFEIGDV 449

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   481 VVQDPSKDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVppgeesgGYVIKASAGSAFFPGRCAEIFVGGQSIGK 560
Cdd:TIGR00471 450 VVKDDKSETRSRVVTKLAVGITHSEANFNEIKSIVAALARELGI-------EYEIEESEHPSFIPGRGAKIVFEGKAIGH 522

                         570       580
                  ....*....|....*....|....*....
gi 51948478   561 LGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:TIGR00471 523 FGEIHPEVLTNFELEFPVSAFEVNIEVFL 551
tRNA_synthFbeta pfam17759
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ...
 377-585 1.26e-58

Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.


Pssm-ID: 465487 [Multi-domain]  Cd Length: 214  Bit Score: 195.08  E-value: 1.26e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   377 IQMTLPKTYTIANQ-FPLNKLTELLRLDMAAAGFTEALTFALCSQEDiADKLGLNISATKAVHIGNPKTAEFQVARTTLL 455
Cdd:pfam17759   1 IPSTLPKGPTTGGGlTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKD-LDKLLEDDPRRKAVKLANPLSEELSVMRTSLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   456 PGLLKTIAANRKMPLP-LKLFEISDIVVQDPSkDVGAKNYRHLCAVYYNK-----------NPGFEIIHGLLDRIMQLLD 523
Cdd:pfam17759  80 PGLLETLAYNLNRGNPdVRLFEIGRVFLPDEL-EELPREPRRLAGLLTGKrlpeswqgkarPVDFYDLKGIVEALLAALG 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 51948478   524 VppgeesGGYVIKASAGSAFFPGRCAEIFVGGQSIGKLGVLHPDVITKFELTMPCSSLEINI 585
Cdd:pfam17759 159 I------DDYEFEAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPQPVYVFELDL 214
PheRS_beta_core cd00769
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ...
 392-588 2.36e-51

Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.


Pssm-ID: 238392 [Multi-domain]  Cd Length: 198  Bit Score: 175.14  E-value: 2.36e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 392 PLNKLTELLRLDMAAAGFTEALTFALCSQEDIADklgLNISATKAVHIGNPKTAEFQVARTTLLPGLLKTIAANRKMP-L 470
Cdd:cd00769   1 PLQKLERKLRRLLAGLGFQEVITYSLTSPEEAEL---FDGGLDEAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKnK 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 471 PLKLFEISDIVVQDPSkdvGAKNYRHLCAVYYNK-----------NPGFEIIHGLLDRIMQLLdvppgEESGGYVIKASA 539
Cdd:cd00769  78 PLRLFEIGRVFLKDED---GPEEEEHLAALLSGNrepeswqgkgrPVDFYDAKGILEALLRAL-----GIIVEFELEELD 149

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 51948478 540 GSAFFPGRCAEIFVGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPF 588
Cdd:cd00769 150 ADLFHPGRSAKIYVNGEVIGFIGELHPEVLKEFDLKEPVYAFELDLDAL 198
PheT COG0072
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ...
 222-589 2.00e-49

Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439842 [Multi-domain]  Cd Length: 793  Bit Score: 183.44  E-value: 2.00e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 222 VIYDSNGVVlSMPPIINGNHSKITVNTRNIFIEC----------T----------------GTDLTKAKIVLDIIVTMFS 275
Cdd:COG0072 303 VIADDEGPL-ALAGVMGGEDSEVTEETTDVLLESayfdpvsirrTarrlglhsdasyrferGVDPALTVAALERATQLIL 381

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 276 EYCENQFTVEAAEVVspsgksstlPELPYRKE-MVRADLINKKVGIKETPANLAKLLTRmcLKSEVIGDGNQIEVEIPPT 354
Cdd:COG0072 382 EIAGGEVGPGIVDVY---------PEPPEPKTiTLRLARINRLLGVEIPAEEIEEILER--LGFEVEEDGDGLTVTVPSW 450

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 355 RADVIHACDIVEDaaIA--YGYNNIQMTLPK-TYTIANQFPLNKLTELLRLDMAAAGFTEALTFALCSQEDiADKLGLNi 431
Cdd:COG0072 451 RFDIEIEADLIEE--VAriYGYDNIPSTLPRaPLAGGGLTEAQRLRRRVRRALAARGYQEVITYSFVSPED-ADLFGLR- 526

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 432 saTKAVHIGNPKTAEFQVARTTLLPGLLKTIAAN--RKMPlPLKLFEISDIVVQDPSKDvgAKNYRHLCAVYY-NKNPG- 507
Cdd:COG0072 527 --REAVRLANPISEDLSVMRTSLLPGLLEAAAYNlnRGQK-DVRLFEIGRVFLPDEGEE--PREPLHLAGVLTgNREPEs 601

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 508 ----------FEIIhGLLDRIMQLLDVPpgeesgGYVIKASAGSAFFPGRCAEIFVGGQSIGKLGVLHPDVITKFELTMP 577
Cdd:COG0072 602 wggkarpvdfFDLK-GDVEALLAALGVP------KLEFEAAEHPALHPGRSAEILLGGKVIGFIGELHPKVLKALDLPGP 674

                       410
                ....*....|..
gi 51948478 578 CSSLEINIEPFL 589
Cdd:COG0072 675 VYVFELDLDALL 686
B3_4 smart00873
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ...
 118-279 7.91e-30

B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.


Pssm-ID: 214876 [Multi-domain]  Cd Length: 174  Bit Score: 115.43  E-value: 7.91e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478    118 RPFAVAAVLRNIKFTkdrYDSFIELQEKLHQNICRKRaLVAIGTHDLDTLSGPFTYTAKRPSDIKFK--PLNKTKEYTAC 195
Cdd:smart00873   1 CPRYLGRVIRGVKNT---RPSPEWLQERLHRAGIRPI-NNVVDITNYVSLETGQPLHAFDLDKIKGKdiPLRRAKEGEKF 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478    196 ELMNiyKTDNHLKHYLHIIESKPLYPVIYDSNGV----------VLSMPPIINGNHS-KITVNTRNIFIECT-----GTD 259
Cdd:smart00873  77 ETLD--GKEYELDEGDLVIADDEGPLALAGVMGGeesevtenttVIFLEPAIFSPRTiRITARTLNLFTDASgrferGVD 154

                          170       180
                   ....*....|....*....|
gi 51948478    260 LTKAKIVLDIIVTMFSEYCE 279
Cdd:smart00873 155 PELVELALDRAAALLLEICG 174
 
Name Accession Description Interval E-value
PLN02265 PLN02265
probable phenylalanyl-tRNA synthetase beta chain
 1-589 0e+00

probable phenylalanyl-tRNA synthetase beta chain


Pssm-ID: 215149 [Multi-domain]  Cd Length: 597  Bit Score: 898.27  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478    1 MPTVSVKRDLLFQVLGRTYTDEEFDELCFEFGLELDEITSEKQIISKEQG----NVKAQGASDVVLYKIDVPANRYDLLC 76
Cdd:PLN02265   1 MPTVSVGRDRLFAALGRTYTQEEFDELCFEFGIELDDVTTEKAIIRKEKHldeeEDGGADDDEEVIYKIDVPANRYDLLC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   77 LEGLARGLQVFKERIKAPVYK-RVMPKGEIQKLIITEETAKVRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRA 155
Cdd:PLN02265  81 LEGLARALRVFLGTEPIPTYRlAEISKGSILKMHVKPETSLIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRT 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  156 LVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDNHLKHYLHIIESKPLYPVIYDSNGVVLSMPP 235
Cdd:PLN02265 161 LVAIGTHDLDTLQGPFTYEALPPEDINFVPLKQTKSFRADELMEFYKSDMKLKKFLHIIENSPVFPVIYDSNRTVLSLPP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  236 IINGNHSKITVNTRNIFIECTGTDLTKAKIVLDIIVTMFSEYCENQFTVEAAEVVSPSGKSSTLPELPYRKEMVRADLIN 315
Cdd:PLN02265 241 IINGAHSAITLDTKNVFIECTATDLTKAKIVLNTMVTMFSEYCARKFEVEPVEVVYPDGKSTVYPDLSVRTMEVDLSYIN 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  316 KKVGIKETPANLAKLLTRMCLKSEVIG-DGNQIEVEIPPTRADVIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLN 394
Cdd:PLN02265 321 SSIGVSLDAEEVASLLNKMQLQAEQSSdDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSMTVGKQQPLN 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  395 KLTELLRLDMAAAGFTEALTFALCSQEDIADKLGLNISATKAVHIGNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKL 474
Cdd:PLN02265 401 QFSDLLRAEVAMAGFTEVLTWILCSHKENFAMLNREDDGNSAVIIGNPRSADFEVVRTSLLPGLLKTLGHNKDAPKPIKL 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  475 FEISDIVVQDPSKDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPPGE--ESGGYVIKASAGSAFFPGRCAEIF 552
Cdd:PLN02265 481 FEVSDVVLLDESKDVGARNSRRLAALYCGTTSGFEVIHGLVDRIMEVLGIPFVEigDNNGYYVEPSNEPEYFPGRQASII 560

                        570       580       590
                 ....*....|....*....|....*....|....*..
gi 51948478  553 VGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:PLN02265 561 YKGKHVGTFGIVHPEVLNNFDIPDPCSFLELDLEPLL 597
pheT_arch TIGR00471
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA ...
 1-589 3.51e-166

phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from eukaryotic cytosol, the Archaea, and spirochetes. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 273096 [Multi-domain]  Cd Length: 551  Bit Score: 484.64  E-value: 3.51e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478     1 MPTVSVKRDLLFQVLgrtyTDEEFDELCFEFGLELDEITSekqiISKEQGNVKaqgasdvvlykIDVPANRYDLLCLEGL 80
Cdd:TIGR00471   1 MPTVTVYKDDLEDLL----IGTDRDEILEELPMMGDEIEG----FDEESPEIK-----------VEFNPNRPDLLSVEGL 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478    81 ARGLQVFKERIKAPVYKRVMPKGeiQKLIITEETAKVRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRALVAIG 160
Cdd:TIGR00471  62 ARSLRGYLGIEKGLKSYDSKKGD--VKLTVDESVLQIRPFITGAVVKGIILNDKVLESLIELQEKLHWNIGRNRRKVAIG 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   161 THDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDnhlKHYLHIIESKPLYPVIYDSNGVVLSMPPIINGN 240
Cdd:TIGR00471 140 IHDLDKVEFPFHYKAVSPNGIKFVPLNSDQEMTPDEILEEHPKG---IRYAHIIEDSDKFPLILDSKDDVLSMPPIINSE 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   241 HSKITVNTRNIFIECTGTDLTKAKIVLDIIVTMFSEYCENQFTVEaaEVVSPSGkSSTLPELPYRKEMVRADLINKKVGI 320
Cdd:TIGR00471 217 LTKLTVNTRNLLIDVTGTDKTAVEITLNIACTMFADRGDGRITVV--EVERPDE-HLGQPNLAPRFMEVSVEYINSLLGL 293

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   321 KETPANLAKLLTRMCLKSEVigDGNQIEVEIPPTRADVIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLNKLTELL 400
Cdd:TIGR00471 294 NLSADEIAHSLKKMRLDAVQ--SDEKLKVVIPAYRVDILHEVDIIEDVAIGYGYNNFPPELPLINTIGRLKPLNKVSDII 371

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   401 RLDMAAAGFTEALTFALCSQEDIADKlgLNISATKAVHIGNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKLFEISDI 480
Cdd:TIGR00471 372 REIMVGLGFQEVIPLTLTSEEVNFKR--MRIEDNNDVKVANPKTLEYTIVRTSLLPGLLETLSENKHHELPQKIFEIGDV 449

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   481 VVQDPSKDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVppgeesgGYVIKASAGSAFFPGRCAEIFVGGQSIGK 560
Cdd:TIGR00471 450 VVKDDKSETRSRVVTKLAVGITHSEANFNEIKSIVAALARELGI-------EYEIEESEHPSFIPGRGAKIVFEGKAIGH 522

                         570       580
                  ....*....|....*....|....*....
gi 51948478   561 LGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:TIGR00471 523 FGEIHPEVLTNFELEFPVSAFEVNIEVFL 551
tRNA_synthFbeta pfam17759
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ...
 377-585 1.26e-58

Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.


Pssm-ID: 465487 [Multi-domain]  Cd Length: 214  Bit Score: 195.08  E-value: 1.26e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   377 IQMTLPKTYTIANQ-FPLNKLTELLRLDMAAAGFTEALTFALCSQEDiADKLGLNISATKAVHIGNPKTAEFQVARTTLL 455
Cdd:pfam17759   1 IPSTLPKGPTTGGGlTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKD-LDKLLEDDPRRKAVKLANPLSEELSVMRTSLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   456 PGLLKTIAANRKMPLP-LKLFEISDIVVQDPSkDVGAKNYRHLCAVYYNK-----------NPGFEIIHGLLDRIMQLLD 523
Cdd:pfam17759  80 PGLLETLAYNLNRGNPdVRLFEIGRVFLPDEL-EELPREPRRLAGLLTGKrlpeswqgkarPVDFYDLKGIVEALLAALG 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 51948478   524 VppgeesGGYVIKASAGSAFFPGRCAEIFVGGQSIGKLGVLHPDVITKFELTMPCSSLEINI 585
Cdd:pfam17759 159 I------DDYEFEAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPQPVYVFELDL 214
PheRS_beta_core cd00769
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ...
 392-588 2.36e-51

Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.


Pssm-ID: 238392 [Multi-domain]  Cd Length: 198  Bit Score: 175.14  E-value: 2.36e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 392 PLNKLTELLRLDMAAAGFTEALTFALCSQEDIADklgLNISATKAVHIGNPKTAEFQVARTTLLPGLLKTIAANRKMP-L 470
Cdd:cd00769   1 PLQKLERKLRRLLAGLGFQEVITYSLTSPEEAEL---FDGGLDEAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKnK 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 471 PLKLFEISDIVVQDPSkdvGAKNYRHLCAVYYNK-----------NPGFEIIHGLLDRIMQLLdvppgEESGGYVIKASA 539
Cdd:cd00769  78 PLRLFEIGRVFLKDED---GPEEEEHLAALLSGNrepeswqgkgrPVDFYDAKGILEALLRAL-----GIIVEFELEELD 149

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 51948478 540 GSAFFPGRCAEIFVGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPF 588
Cdd:cd00769 150 ADLFHPGRSAKIYVNGEVIGFIGELHPEVLKEFDLKEPVYAFELDLDAL 198
pheT PRK00629
phenylalanyl-tRNA synthetase subunit beta; Reviewed
 56-589 1.46e-49

phenylalanyl-tRNA synthetase subunit beta; Reviewed


Pssm-ID: 234804 [Multi-domain]  Cd Length: 791  Bit Score: 183.83  E-value: 1.46e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   56 GASDVVLyKIDVPANRYDLLCLEGLARGLQV-FKERIKAPVYKRVMPKGEIQKLIITEETAKVRPFAvAAVLRNIKFTKD 134
Cdd:PRK00629 151 GLDDTVI-EISLTPNRADCLSVRGIARELAAlLGLPLKLPEIEPVPATIDDKLPVEIEDPDLCPRYA-GRVIKGVKNIAP 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  135 rydSFIELQEKLHQNICR-KRALVAI--------G--TH--DLDTLSGPFTytAKR-PSDIKFKPLNKtKEYTaceLmni 200
Cdd:PRK00629 229 ---SPLWLQERLRAAGIRpINNVVDItnyvmlelGqpLHafDLDKIGGGIV--VRRaKEGEKLTTLDG-KERT---L--- 296

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  201 ykTDNHLkhylhiieskplypVIYDSNGVVlSMPPIINGNHSKITVNTRNIFIEC------------------T------ 256
Cdd:PRK00629 297 --DPEDL--------------VIADDKKPL-ALAGVMGGEDSEVTENTTNVLLESayfdpvsirktarrlglrTdasyrf 359

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  257 --GTDLTKAKIVLDIIVTMFSEYCENqftvEAAEVVSPSGKSSTLPELPyrkemVRADLINKKVGIKETPANLAKLLTRM 334
Cdd:PRK00629 360 erGVDPALTLLALERATALILELGGG----EVVEGVVDVYPLPKEPTIT-----LRLERINRLLGTEISDEEIVDILKRL 430

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  335 CLKSEVIGDGnQIEVEIPPTRADVIHACDIVEDaaIA--YGYNNIQMTLPK-TYTIANQFPLNKLTELLRLDMAAAGFTE 411
Cdd:PRK00629 431 GFEVTEVDGD-GLTVTVPSWRFDIEIEEDLVEE--VAriYGYDNIPSTPPVaALTMGGLTEAQRLLRRLRRALAALGYQE 507

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  412 ALTFALCSQEDiADKLGLNisaTKAVHIGNPKTAEFQVARTTLLPGLLKTIAAN--RKMPLpLKLFEISDIVVQDpskDV 489
Cdd:PRK00629 508 VITYSFVSPED-AKLFGLN---PEPLLLLNPISEELSVMRTSLLPGLLEAVAYNlnRGNKD-VALFEIGRVFLPD---GD 579

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  490 GAKNYRHLCAVYYNKNPG-----------FEIIhGLLDRIMQLLDVPPGEesggyVIKASAGSAFFPGRCAEIFVGGQSI 558
Cdd:PRK00629 580 LPREPEHLAGVLTGNRVEeswggkrpvdfFDLK-GDVEALLEALGLPEVE-----FVAEFEAAALHPGRSAEIYLDGKVI 653

                        570       580       590
                 ....*....|....*....|....*....|.
gi 51948478  559 GKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:PRK00629 654 GFIGELHPKVLKKLDLPGRTYVFELDLDALL 684
PheT COG0072
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ...
 222-589 2.00e-49

Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439842 [Multi-domain]  Cd Length: 793  Bit Score: 183.44  E-value: 2.00e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 222 VIYDSNGVVlSMPPIINGNHSKITVNTRNIFIEC----------T----------------GTDLTKAKIVLDIIVTMFS 275
Cdd:COG0072 303 VIADDEGPL-ALAGVMGGEDSEVTEETTDVLLESayfdpvsirrTarrlglhsdasyrferGVDPALTVAALERATQLIL 381

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 276 EYCENQFTVEAAEVVspsgksstlPELPYRKE-MVRADLINKKVGIKETPANLAKLLTRmcLKSEVIGDGNQIEVEIPPT 354
Cdd:COG0072 382 EIAGGEVGPGIVDVY---------PEPPEPKTiTLRLARINRLLGVEIPAEEIEEILER--LGFEVEEDGDGLTVTVPSW 450

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 355 RADVIHACDIVEDaaIA--YGYNNIQMTLPK-TYTIANQFPLNKLTELLRLDMAAAGFTEALTFALCSQEDiADKLGLNi 431
Cdd:COG0072 451 RFDIEIEADLIEE--VAriYGYDNIPSTLPRaPLAGGGLTEAQRLRRRVRRALAARGYQEVITYSFVSPED-ADLFGLR- 526

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 432 saTKAVHIGNPKTAEFQVARTTLLPGLLKTIAAN--RKMPlPLKLFEISDIVVQDPSKDvgAKNYRHLCAVYY-NKNPG- 507
Cdd:COG0072 527 --REAVRLANPISEDLSVMRTSLLPGLLEAAAYNlnRGQK-DVRLFEIGRVFLPDEGEE--PREPLHLAGVLTgNREPEs 601

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478 508 ----------FEIIhGLLDRIMQLLDVPpgeesgGYVIKASAGSAFFPGRCAEIFVGGQSIGKLGVLHPDVITKFELTMP 577
Cdd:COG0072 602 wggkarpvdfFDLK-GDVEALLAALGVP------KLEFEAAEHPALHPGRSAEILLGGKVIGFIGELHPKVLKALDLPGP 674

                       410
                ....*....|..
gi 51948478 578 CSSLEINIEPFL 589
Cdd:COG0072 675 VYVFELDLDALL 686
PhetRS_B1 pfam18262
Phe-tRNA synthetase beta subunit B1 domain; This is the N-terminal domain found in human ...
 1-90 4.03e-37

Phe-tRNA synthetase beta subunit B1 domain; This is the N-terminal domain found in human cytosolic phenylalanyl tRNA synthetase beta subunit.


Pssm-ID: 408077  Cd Length: 83  Bit Score: 132.54  E-value: 4.03e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478     1 MPTVSVKRDLLFQVLGRTYTDEEFDELCFEFGLELDEITSEKqiiskeqGNVKAQGASDVVLYKIDVPANRYDLLCLEGL 80
Cdd:pfam18262   1 MPTISVKKVRLFKVLGRVYTEEEFSDLCFEFGLELDEITSEE-------NQLKTSWRSEEVVYKIDIPANRYDLLCVEGL 73

                          90
                  ....*....|
gi 51948478    81 ARGLQVFKER 90
Cdd:pfam18262  74 ATALLIFKGK 83
B3_4 smart00873
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ...
 118-279 7.91e-30

B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.


Pssm-ID: 214876 [Multi-domain]  Cd Length: 174  Bit Score: 115.43  E-value: 7.91e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478    118 RPFAVAAVLRNIKFTkdrYDSFIELQEKLHQNICRKRaLVAIGTHDLDTLSGPFTYTAKRPSDIKFK--PLNKTKEYTAC 195
Cdd:smart00873   1 CPRYLGRVIRGVKNT---RPSPEWLQERLHRAGIRPI-NNVVDITNYVSLETGQPLHAFDLDKIKGKdiPLRRAKEGEKF 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478    196 ELMNiyKTDNHLKHYLHIIESKPLYPVIYDSNGV----------VLSMPPIINGNHS-KITVNTRNIFIECT-----GTD 259
Cdd:smart00873  77 ETLD--GKEYELDEGDLVIADDEGPLALAGVMGGeesevtenttVIFLEPAIFSPRTiRITARTLNLFTDASgrferGVD 154

                          170       180
                   ....*....|....*....|
gi 51948478    260 LTKAKIVLDIIVTMFSEYCE 279
Cdd:smart00873 155 PELVELALDRAAALLLEICG 174
B3_4 pfam03483
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ...
 117-278 2.52e-19

B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.


Pssm-ID: 427327 [Multi-domain]  Cd Length: 174  Bit Score: 85.68  E-value: 2.52e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   117 VRPFAVAAVLRNIKFTKDrydSFIELQEKLHQniCRKR---ALV------------AIGTHDLDTLSGPFTytakrpsdi 181
Cdd:pfam03483   1 ACPRYFGRVIRGVKKNRP---SPEWLQRRLRR--AGIRpinNVVditnyvmlelgqPLHAFDLDKIAGDIV--------- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   182 kfKPLNKTKEytacELMNIYKTDNHLKhylhiieskPLYPVIYDSNGVVlSMPPIINGNHSKITVNTRNIFIECT----- 256
Cdd:pfam03483  67 --VRLAKGGE----KFTTLDGKERELD---------PGDLVIADDDGPV-ALAGIMGGEESEVTEDTTNIFLESAgfdpv 130

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 51948478   257 ---------------------GTDLTKAKIVLDIIVTMFSEYC 278
Cdd:pfam03483 131 airktarrlglrtdasyrferGVDPELVEAALDRATALLLELC 173
B5 pfam03484
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
 309-374 4.99e-18

tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.


Pssm-ID: 460942 [Multi-domain]  Cd Length: 67  Bit Score: 78.20  E-value: 4.99e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 51948478   309 VRADLINKKVGIKETPANLAKLLTRMCLKSEVIgDGNQIEVEIPPTRADVIHACDIVEDAAIAYGY 374
Cdd:pfam03484   3 LRLDRINRLLGIDLSAEEIVEILERLGFEVEEE-DGDTLTVTVPSYRPDILHEADLIEEVARIYGY 67
B5 smart00874
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
 305-374 3.20e-17

tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.


Pssm-ID: 197942 [Multi-domain]  Cd Length: 68  Bit Score: 75.99  E-value: 3.20e-17
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478    305 RKEMVRADLINKKVGIKETPANLAKLLTRMCLKSEVIGDGnqIEVEIPPTRADVIHACDIVEDAAIAYGY 374
Cdd:smart00874   1 RTITLRLERINRLLGLEILAEEIEEILKRLGFEVEVSGDT--LEVTVPSYRFDILIEADLIEEVARIYGY 68
syfB CHL00192
phenylalanyl-tRNA synthetase beta chain; Provisional
 32-587 3.10e-11

phenylalanyl-tRNA synthetase beta chain; Provisional


Pssm-ID: 214391 [Multi-domain]  Cd Length: 704  Bit Score: 66.27  E-value: 3.10e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478   32 GLELDEITSekqiiskeqgnVKAQGASDVVLyKIDVPANRYDLLCLEGLARGLQVF--KERIKAPVYKRVMPKGEIQKLI 109
Cdd:CHL00192  30 GFEVEDILS-----------VKIGGESDIIL-DISSTANRSDVLSIQGLSREISALfnSDPIKLKYYNPSISWFDKLKNL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  110 ITEETAKVR-PFAVAAVLRNIKftkdRYDSFIELQEKLhqnicrkralVAIGTHDLDTLSGPFTYTA-KRPSDIKFKPLN 187
Cdd:CHL00192  98 ISNDSSKLNcSMFIAVIIENIE----IKDSPKWLQNRL----------SSSGFKSLNNLTDIQNYIMlETGQPIEIYDLD 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  188 KtkeytacelmnIYKTDNhlKHYLHIIESKPLYP---VIYDS--------------NGVVLSMPPIINGNHSKITVNTRN 250
Cdd:CHL00192 164 K-----------IYSKNT--TSSLALSSKFALQKssfIASNSknielennilvvqaNNVIISIAGIISNEEIICDKNTKS 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  251 IFIE---CTGTDLTKAKIVLDIiVTMFSEYCENQftveaaevvspsGKSSTLPELPYR----------KEMVRADLINKK 317
Cdd:CHL00192 231 ILIEasiFDAAVIRKSSRKLGL-RTDRSIRYEKS------------LKNDNLLEAYYRlvsllrilnpKLKCKFHFIYKK 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  318 ------------VGIKE--------------TPANLAKLLTRMCLKSEVIGDGNQIEVEIPPTRA-DVIHACDIVEDAAI 370
Cdd:CHL00192 298 iknssrriklsyKKIKDilgpikintntrylSPKEITNALKRLNFKITYDSLKLNWEVLIPSYRKdDIVREIDVIEEIAR 377

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  371 AYGYNNIQMTLPKTYTIAN-----QFpLNKLTELLRldmaAAGFTEALTFALCSQEDIADKlglNISatkavhIGNPKTA 445
Cdd:CHL00192 378 IYGFNNFLSKLPNIKFIGRldidyNT-RDKIRSYLR----NLGLTELIHYSLVKQESFSKN---EIK------LKNPLIK 443

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51948478  446 EFQVARTTLLPGLLKTIAAN-RKMPLPLKLFEISDIVVQDPSKDVGAKNYRHLCA-------VYYNKNPGFEIIH--GLL 515
Cdd:CHL00192 444 DYSTLRSSLLPGLIEAVQENlKQGNSTLEGFEIGHVFNLDSSSIIEETELAGGIFggidirsSWSEKAQSLNWFEakGII 523

                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 51948478  516 DRIMQLLDVPPgeesggYVIKASAGSA---FFPGRCAEIFV-GGQSIGKLGVLHPDVITKFELTMPCSSLEINIEP 587
Cdd:CHL00192 524 ENFFQKLNLPI------YWKKYSDLDEkinFHPYCTSEIFLsNGQKIGIFGQLHPLLANKLNLNTEIYLFEINLDI 593
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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