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Conserved domains on  [gi|518505941|ref|WP_019676148|]
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TonB-dependent receptor domain-containing protein [Arsukibacterium perlucidum]

Protein Classification

TonB-dependent receptor( domain architecture ID 1003263)

TonB-dependent receptor interacts with outer membrane receptor proteins that carry out high-affinity binding and energy-dependent uptake of specific substrates into the periplasmic space

CATH:  2.40.170.20
PubMed:  21455261|12409204
SCOP:  4003084
TCDB:  1.B.14

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Fiu super family cl34816
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
75-807 1.04e-47

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


The actual alignment was detected with superfamily member COG4774:

Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 180.07  E-value: 1.04e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  75 EDIDVSSPRSTAEIFRMLPGVRSESTGGEGNANIAVRGLPVAAGgakfltLQEDGLPvlqfgDIAFGNADIFvradsTMA 154
Cdd:COG4774   19 ELIEDQGATSLADALRNVPGVTFGAGEGGNGDSFSIRGFSASGD------IYVDGLR-----DPGQYRRDTF-----NLE 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 155 RLDVIRGGSASTAASNSPGGIINFISKT-GEHQGGSIAISSGlNYDQFRTDFEFGGDINNDMRFHFGGFVRQGEGVRDPG 233
Cdd:COG4774   83 RVEVLKGPASVLYGRGSPGGVINLVTKRpTDEPFTEVTLTYG-SDGQRRATLDVNGPLGDDLAYRLNGMYRDSDSYRDGV 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 234 YQgeRGYQIKANVTKEFSAGY-VRVYAKHLNDRAASYMPMPMYADGSSVPgydaqkdtlqsvyltqtvrLNGDNQIsrGD 312
Cdd:COG4774  162 DN--DRWGIAPSLTWRLGDRTrLTLDYEYQDDDRTPDYGVPAVANGRPVD-------------------VDRSTFY--GQ 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 313 VRNGMNPKVDSFGIEAQFDLDENWTLDNRFRISDVSGNFITlfpaevgnaqgiadsiagnnstlTYAVGPQAGQNYTAAD 392
Cdd:COG4774  219 PDDYSDSETDSATLRLEHDFNDNWTLRNALRYSDYDRDYRN-----------------------TYPTGGNATGTVTRSA 275
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 393 AMRIHTFDVEINDfgsmvNDLKLARSFGDVDVTFgyymadqTISMSWLWNSYLMALKGNNAELLNVNAADGTafseqgql 472
Cdd:COG4774  276 YRRDQDNDTLSNQ-----TDLTGKFDTGGVKHTL-------LAGVEYSREDSDNARYSGGGTAPTVNLYNPV-------- 335
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 473 aYGVPFWG-NCCQRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGTYAGASQSSRDmnndgaisqieqsvsgi 550
Cdd:COG4774  336 -YGAPVTGpTLGGADNDSRTDTTGLYLQDTISLTDrWSLLAGLRYDRFDTDYTDRTTGATTSS----------------- 397
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 551 dlanpqlvnYSWGYNSYSAGANYQFNRDWAMFGRISKGARANADrlLFGKVNADGSVAREDAidevKQYEIGSKS--RHG 628
Cdd:COG4774  398 ---------YDDSAFSPRAGLVYKPTPNLSLYASYSTSFNPGGG--APSLSNAGQALDPEKS----RQYEVGVKWdlLDG 462
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 629 NLNLFATLFFAE-TDEQNFEATTQLFFDRV--YKAKGIELESSYRIGD-FDFRGSVTFTDAEISSDAlNPDVVGNTPRRQ 704
Cdd:COG4774  463 RLSLTAALFRIEkTNVRTTDPANPGVYVQTgeQRSRGVELEATGELTPgWSVLAGYTYLDAEITKSA-NAANVGNRLPNV 541
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 705 ADMIYSLLARY--TMDNAQVGISLVGTTDSYAQDNNDLKFSGYTQLNAFANYELAENLTLSLNVNNLFDTIGITEAeqgs 782
Cdd:COG4774  542 PRHSASLWTTYdlPLPGLTLGGGVRYVGSRYADAANTVKLPSYTRFDAGASYRLNKNLTLRLNVNNLTDKRYYASA---- 617
                        730       740
                 ....*....|....*....|....*
gi 518505941 783 vpeNGIITARTINGRTASVGLRYQF 807
Cdd:COG4774  618 ---YGSGYVTPGAPRTVLLSASYRF 639
 
Name Accession Description Interval E-value
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
75-807 1.04e-47

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 180.07  E-value: 1.04e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  75 EDIDVSSPRSTAEIFRMLPGVRSESTGGEGNANIAVRGLPVAAGgakfltLQEDGLPvlqfgDIAFGNADIFvradsTMA 154
Cdd:COG4774   19 ELIEDQGATSLADALRNVPGVTFGAGEGGNGDSFSIRGFSASGD------IYVDGLR-----DPGQYRRDTF-----NLE 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 155 RLDVIRGGSASTAASNSPGGIINFISKT-GEHQGGSIAISSGlNYDQFRTDFEFGGDINNDMRFHFGGFVRQGEGVRDPG 233
Cdd:COG4774   83 RVEVLKGPASVLYGRGSPGGVINLVTKRpTDEPFTEVTLTYG-SDGQRRATLDVNGPLGDDLAYRLNGMYRDSDSYRDGV 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 234 YQgeRGYQIKANVTKEFSAGY-VRVYAKHLNDRAASYMPMPMYADGSSVPgydaqkdtlqsvyltqtvrLNGDNQIsrGD 312
Cdd:COG4774  162 DN--DRWGIAPSLTWRLGDRTrLTLDYEYQDDDRTPDYGVPAVANGRPVD-------------------VDRSTFY--GQ 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 313 VRNGMNPKVDSFGIEAQFDLDENWTLDNRFRISDVSGNFITlfpaevgnaqgiadsiagnnstlTYAVGPQAGQNYTAAD 392
Cdd:COG4774  219 PDDYSDSETDSATLRLEHDFNDNWTLRNALRYSDYDRDYRN-----------------------TYPTGGNATGTVTRSA 275
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 393 AMRIHTFDVEINDfgsmvNDLKLARSFGDVDVTFgyymadqTISMSWLWNSYLMALKGNNAELLNVNAADGTafseqgql 472
Cdd:COG4774  276 YRRDQDNDTLSNQ-----TDLTGKFDTGGVKHTL-------LAGVEYSREDSDNARYSGGGTAPTVNLYNPV-------- 335
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 473 aYGVPFWG-NCCQRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGTYAGASQSSRDmnndgaisqieqsvsgi 550
Cdd:COG4774  336 -YGAPVTGpTLGGADNDSRTDTTGLYLQDTISLTDrWSLLAGLRYDRFDTDYTDRTTGATTSS----------------- 397
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 551 dlanpqlvnYSWGYNSYSAGANYQFNRDWAMFGRISKGARANADrlLFGKVNADGSVAREDAidevKQYEIGSKS--RHG 628
Cdd:COG4774  398 ---------YDDSAFSPRAGLVYKPTPNLSLYASYSTSFNPGGG--APSLSNAGQALDPEKS----RQYEVGVKWdlLDG 462
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 629 NLNLFATLFFAE-TDEQNFEATTQLFFDRV--YKAKGIELESSYRIGD-FDFRGSVTFTDAEISSDAlNPDVVGNTPRRQ 704
Cdd:COG4774  463 RLSLTAALFRIEkTNVRTTDPANPGVYVQTgeQRSRGVELEATGELTPgWSVLAGYTYLDAEITKSA-NAANVGNRLPNV 541
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 705 ADMIYSLLARY--TMDNAQVGISLVGTTDSYAQDNNDLKFSGYTQLNAFANYELAENLTLSLNVNNLFDTIGITEAeqgs 782
Cdd:COG4774  542 PRHSASLWTTYdlPLPGLTLGGGVRYVGSRYADAANTVKLPSYTRFDAGASYRLNKNLTLRLNVNNLTDKRYYASA---- 617
                        730       740
                 ....*....|....*....|....*
gi 518505941 783 vpeNGIITARTINGRTASVGLRYQF 807
Cdd:COG4774  618 ---YGSGYVTPGAPRTVLLSASYRF 639
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
75-807 2.87e-36

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 145.67  E-value: 2.87e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  75 EDIDVSSPRSTAEIFRMLPGVRSESTGGEGNANIAVRGLpvaagGAKFLTLQEDGLPVLQFGDIAFGNADIFvraDSTMA 154
Cdd:cd01347    8 EDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISIRGF-----GPDRTLVLVDGLPLASSNYGRGVDLNTI---PPELI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 155 -RLDVIRGGSASTAASNSPGGIINFISKTGEHQ-GGSIAISSGLN--YDQFRTDFEFGGDI--NNDMRFHFGGFVRQGEG 228
Cdd:cd01347   80 eRVEVLKGPSSALYGSGAIGGVVNIITKRPTDEfGGSVTAGYGSDnsGSSGGGGFDVSGALadDGAFGARLYGAYRDGDG 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 229 VRDPGYQGER------------GYQIKANVTKEFSAGYvrvyAKHLNDRAasYMPMPMYADGSSVPGydaqkdtlqsvyl 296
Cdd:cd01347  160 TIDGDGQADDsdeerynvagklDWRPDDDTRLTLDAGY----QDQDADGP--GGTLPANGTGSSLGG------------- 220
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 297 TQTVRLNGDNQISRGDVRNGMNpkvdSFGIEAQFDlDENWTLDNRFRISDVSGNFITLFPAEVGNAQGIADSIAGNNSTL 376
Cdd:cd01347  221 GPSSNTNGDRDWDYRDRYRKRA----SLGLEHDLN-DTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSER 295
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 377 TYavgpqagqnytaadamRIHTFDVEINdfgsmvndlklaRSFGDVDVTFgyymadqtismswlwnsylmalkgnnaell 456
Cdd:cd01347  296 DT----------------TQLGFDAGLN------------APFGTGPVAH------------------------------ 317
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 457 nvnaadgtafseqgQLAYGVPFwgnccqRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGTYAGASQSSRDMN 535
Cdd:cd01347  318 --------------TLTLGVEY------RREELDEKQTALYAQDTIELTDdLTLTLGLRYDHYDQDSKDTIAGGTTAKKS 377
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 536 NDgaisqieqsvsgidlanpqlvnyswgYNSYSAGANYQFNRDWAMFGRISKGARANADRLLFGKVNADGSVARED---A 612
Cdd:cd01347  378 YS--------------------------HWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAAVGNpnlK 431
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 613 IDEVKQYEIGSKSRHGN-LNLFATLF--------FAETDEQNFEATTQLFFDRVYKAKGIELESSYRIGD-FDFRGSVTF 682
Cdd:cd01347  432 PEKSKQYELGLKYDPGDgLTLSAALFridikneiVSTPTNTGLGLVTVYVNGGKARIRGVELEASYDLTDgLGLTGSYTY 511
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 683 TDAEISSDALNPDvvGNTPRRQADMIYSLLARYTMDNAQVGISLVGT-----TDSYAQDNNDLKFSGYTQLNAFANYELA 757
Cdd:cd01347  512 TDTEVKRTDGATT--GNRLPGIPKHTANLGLDYELPDEGLTAGGGVRyrgkqYADTANGNNTVKVPGYTLVDLSASYQFT 589
                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|
gi 518505941 758 ENLTLSLNVNNLFDTigiTEAEQGSVPENGIITArTINGRTASVGLRYQF 807
Cdd:cd01347  590 KNLTLRLGVNNLFDK---DYYTSLSVRGSGLYGY-YGPGRTYYLSVSYKF 635
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
71-807 3.22e-24

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 108.27  E-value: 3.22e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941   71 TLTFEDIDVSSPRSTAEIFRMLPGVRSESTGGEGN-ANIAVRGLPVAAGGAKFLTlqeDGLPVLqfgdiafGNADIFVRA 149
Cdd:TIGR01783   8 VITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQfGNITIRGFGLEVDIDNVYL---DGVPLL-------SRGNLAIVD 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  150 DSTMARLDVIRGGSASTAASNSPGGIINFISKTG-EHQGGSIAISSGlNYDQFRTDFEFGGDINNDmrFHFGGFV----R 224
Cdd:TIGR01783  78 PAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPqDEPKGSVTFGAG-TRSGYRTAFDLGGPLGAD--GTFRGRLngarQ 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  225 QGEGVRDpgYQGER--------GYQIKANVTKEFSAGYvRVYAKHLNDRAASYMPmpmyadgsSVPGYDAQKDTLQSvyl 296
Cdd:TIGR01783 155 DGDSFYD--GAGEEtrlgatatDWQLDDRTLLRLGAYY-QKERDRGGYGGLPASG--------GTSGRDLSSDRYLG--- 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  297 TQTVRLNGDNQISRGdvrngmnpkvdsfGIEAQFDLDENWTLDNRFRISDVSGNFITLFPAEVGNAQGIADSIAGNNSTL 376
Cdd:TIGR01783 221 TSSNRNYDDREYLSY-------------GLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVNVK 287
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  377 TYAVGPQAGQNytaadaMRIHTFDVEIndfgsmvndlklarsfgdvdvTFGYYMADQTISMSWLWNSYLMALKGNNAELL 456
Cdd:TIGR01783 288 QDRVQIDAGLD------GEFETGPIEH---------------------DLLLGVSYGQRTTNRFNNTGYPSDNIYSLTAT 340
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  457 NVNAADGTAFSEQGQLaygvpfwgnccqrnYDTQYSTTAPYINVGWAFGDWSLDASVRRDNGKatgtyagasqssRDMNN 536
Cdd:TIGR01783 341 SSARTDIGDSPKDRAL--------------SSTTKALNGVALQRILLADKWTLTLGGRYDSVD------------VKSNN 394
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  537 DGAISQIEQSVSgidlanpqlvNYSWgynsySAGANYQFNRDWAMFGRISKGARANADRLLFGKVNADGSVAredaiDEV 616
Cdd:TIGR01783 395 GVAGSTGKRDDS----------QFTP-----SLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGNSGDILEP-----EKG 454
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  617 KQYEIGSKSRHGNLNLF-ATLF---FAETDEQNFEATTQLFFDRVYKAKGIELESSYRIGD-FDFRGSVTFTDAEISSDA 691
Cdd:TIGR01783 455 KNYELGVRYDLGDSLLAtAALFritKDNQLVQDPVNGTFSVNAGKTRNRGVELEARGYLTPgLSLSAGYTYTDAEFTEDT 534
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  692 lNPDVVGNTPRRQADMIYSLLARY---TMDNA-QVGISLVGTTDSYAQDNNDLKFSGYTQLNAFANYELA--ENLTLSLN 765
Cdd:TIGR01783 535 -NGDTQGNTVPFVPKHTASLWASYappVGDNGlTLGGGVQYTGKAYVDGGNTGKVPSYTVVDLSVRYDLTkkKNLTLALN 613
                         730       740       750       760
                  ....*....|....*....|....*....|....*....|..
gi 518505941  766 VNNLFDTIGITEAEQGSvPENGIITARtinGRTASVGLRYQF 807
Cdd:TIGR01783 614 VNNLFDRDYYTSGYRWG-PSAYIYPGA---PRTVGLSVSYDF 651
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
398-806 2.37e-22

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 101.39  E-value: 2.37e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  398 TFDVEINDFGSMVNDLKLARSFGDVDVTFGYYMADQTISMSWLWNSYLMALKGNNAELLNVNAADGTAFSEQGQLAYGVP 477
Cdd:pfam00593  66 GYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLD 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  478 F-------------WGNCCQRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGTYAGASQSSrdmnndgaisqi 543
Cdd:pfam00593 146 YrrldddaydpydpANPSSSSYSDTTTDSYGLYLQDNIKLTDrLTLTLGLRYDHYSTDGDDGNGGGDN------------ 213
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  544 eqsvsgidlanpqlVNYSWGYNSYSAGANYQFNRDWAMFGRISKGARA-NADRLLFGKVNADGSVAREDAID----EVKQ 618
Cdd:pfam00593 214 --------------FSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRApSLGELYGSGSGGGGGAVAGGNPDlkpeTSDN 279
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  619 YEIGSKSRHGNLNLFATLFFAE-TDEQNFEATTQLFFDRVY--------KAKGIELESSYRI-GDFDFRGSVTFTDAEis 688
Cdd:pfam00593 280 YELGLKYDDGRLSLSLALFYIDiKNLITSDPDGPGLGGTVYtytnvgkaRIRGVELELSGRLwGLGLSGGGYTYTDAD-- 357
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  689 sDALNPDVVGNTPRRQADMIYSLLARYTMDN----AQVGISLVGTTDSYAQD-NNDLKFSGYTQLNAFANYELAENLTLS 763
Cdd:pfam00593 358 -DDADADDTGNPLPNVPRHTANLGLTYDFPLggwgARLGARYVGSGERRYGDaANTFKTPGYTLVDLSAGYRLNKNLTLR 436
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 518505941  764 LNVNNLFDtigiTEAEQGSVPENGIITARTINGRTASVGLRYQ 806
Cdd:pfam00593 437 LGVNNLFD----KYYKRYYSSGGGNLGGYPGPGRTFYLGLSYK 475
PRK14050 PRK14050
TonB-dependent siderophore receptor;
87-771 1.27e-12

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 71.37  E-value: 1.27e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  87 EIFRMLPGVRSESTGGEGNAN-IAVRGLPVAAGGAkFLtlqeDGLPVLQFGdiaFGNADIfvraDSTM-ARLDVIRGGSA 164
Cdd:PRK14050 102 EALRYTPGVLSQPFGTDGDTDwFYIRGFDATQTGV-FL----DGLNLFSYG---FGGFQI----DPFMlERVEVLKGPAS 169
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 165 STAASNSPGGIINFISK--TGE-HQGGSIAISsglNYDQFRTDFEFGGDINND--MRFHFGGFVRQGEGVRDpGYQGERG 239
Cdd:PRK14050 170 VLYGGSNPGGIVNMVSKrpLDEpLYYTEIGIN---SYGNAFTGFDVGDKLSDDgtVRYRVTGKVAGGDNYSD-YSEDLRG 245
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 240 YqIKANVTKEFSAGY---VRVYAKHLNDRAASYMPMPMYADGSSVPGYDAQKDtlqsvyltqtvRLNGDNQISRGDVRNG 316
Cdd:PRK14050 246 F-IMPQITYAPDDATsltVYGYLSGLDQVHVGNGFLPYVGTVVDAPFGKIDRD-----------AFYGEPDIDNGSYAQQ 313
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 317 MnpkvdsFGIEAQFDLDENWTLDNRFRISDVSGNFITLFP-AEVGNAQGIADSIAGNNSTLTYAVGPQAGQNYTAADAMR 395
Cdd:PRK14050 314 M------LGYEFSHEFDNGWTFSQNARYGHLHKHEKGPYTyGYVGGATGLPDPTGPDYMLNRIGFEHRSKVDSFSIDNRL 387
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 396 IHTFDVeindfGSMVNDLKLArsfgdvdVTFGYYMADQtismswlwnsyLMALKGNNAellnVNAADGTafseqgqlaYG 475
Cdd:PRK14050 388 EGEFDT-----GALTHNLLFG-------LDYKYYRLDQ-----------VQACCGATP----ISATNPV---------YG 431
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 476 VPFWGNCCQRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGtyAGASQSSRDmNNDGAISQieqsvsgidlan 554
Cdd:PRK14050 432 TTQGANFVYLDQILTQQQIGIYAQDQIRFGDgWLVTLNGRYDYVDTDS--DARIGTSYE-SNDGALSG------------ 496
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 555 pqlvnyswgynsySAGANYQFnrDWAMFGRISKGARANAdrlLFGkVNADGSVAREDaidEVKQYEIGSKSRHGNLN--L 632
Cdd:PRK14050 497 -------------RAGLAYEF--DNGLTPYVSAATFFNP---LVG-TLASGPPLKPE---EGEQYEAGIKYEPSFIDglI 554
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 633 FATLFfaETDEQNFEATTQLFFDRV----YKAKGIELESSYRIGD-FDFRGSVTFTDAEISSDAlNPDVVGNTPRRQADM 707
Cdd:PRK14050 555 TASVF--QITKKNVTVTDPLTFASTqlgeVRSRGFELEGKVNLDDnWKALASFTYTDLEITEDA-NPSLIGNSPYLVPET 631
                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 518505941 708 IYSLLARYTM-DNAQVGISLVGTT----DSYAQDNNDLKFSGYTQLNAFANYElAENLTLSLNVNNLFD 771
Cdd:PRK14050 632 QASLWLDYAVtDGAFEGVSLGAGVryqgESWADEANTLKVPAATLFDAAIRYE-KNDWGASLNVANLFD 699
 
Name Accession Description Interval E-value
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
75-807 1.04e-47

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 180.07  E-value: 1.04e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  75 EDIDVSSPRSTAEIFRMLPGVRSESTGGEGNANIAVRGLPVAAGgakfltLQEDGLPvlqfgDIAFGNADIFvradsTMA 154
Cdd:COG4774   19 ELIEDQGATSLADALRNVPGVTFGAGEGGNGDSFSIRGFSASGD------IYVDGLR-----DPGQYRRDTF-----NLE 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 155 RLDVIRGGSASTAASNSPGGIINFISKT-GEHQGGSIAISSGlNYDQFRTDFEFGGDINNDMRFHFGGFVRQGEGVRDPG 233
Cdd:COG4774   83 RVEVLKGPASVLYGRGSPGGVINLVTKRpTDEPFTEVTLTYG-SDGQRRATLDVNGPLGDDLAYRLNGMYRDSDSYRDGV 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 234 YQgeRGYQIKANVTKEFSAGY-VRVYAKHLNDRAASYMPMPMYADGSSVPgydaqkdtlqsvyltqtvrLNGDNQIsrGD 312
Cdd:COG4774  162 DN--DRWGIAPSLTWRLGDRTrLTLDYEYQDDDRTPDYGVPAVANGRPVD-------------------VDRSTFY--GQ 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 313 VRNGMNPKVDSFGIEAQFDLDENWTLDNRFRISDVSGNFITlfpaevgnaqgiadsiagnnstlTYAVGPQAGQNYTAAD 392
Cdd:COG4774  219 PDDYSDSETDSATLRLEHDFNDNWTLRNALRYSDYDRDYRN-----------------------TYPTGGNATGTVTRSA 275
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 393 AMRIHTFDVEINDfgsmvNDLKLARSFGDVDVTFgyymadqTISMSWLWNSYLMALKGNNAELLNVNAADGTafseqgql 472
Cdd:COG4774  276 YRRDQDNDTLSNQ-----TDLTGKFDTGGVKHTL-------LAGVEYSREDSDNARYSGGGTAPTVNLYNPV-------- 335
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 473 aYGVPFWG-NCCQRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGTYAGASQSSRDmnndgaisqieqsvsgi 550
Cdd:COG4774  336 -YGAPVTGpTLGGADNDSRTDTTGLYLQDTISLTDrWSLLAGLRYDRFDTDYTDRTTGATTSS----------------- 397
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 551 dlanpqlvnYSWGYNSYSAGANYQFNRDWAMFGRISKGARANADrlLFGKVNADGSVAREDAidevKQYEIGSKS--RHG 628
Cdd:COG4774  398 ---------YDDSAFSPRAGLVYKPTPNLSLYASYSTSFNPGGG--APSLSNAGQALDPEKS----RQYEVGVKWdlLDG 462
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 629 NLNLFATLFFAE-TDEQNFEATTQLFFDRV--YKAKGIELESSYRIGD-FDFRGSVTFTDAEISSDAlNPDVVGNTPRRQ 704
Cdd:COG4774  463 RLSLTAALFRIEkTNVRTTDPANPGVYVQTgeQRSRGVELEATGELTPgWSVLAGYTYLDAEITKSA-NAANVGNRLPNV 541
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 705 ADMIYSLLARY--TMDNAQVGISLVGTTDSYAQDNNDLKFSGYTQLNAFANYELAENLTLSLNVNNLFDTIGITEAeqgs 782
Cdd:COG4774  542 PRHSASLWTTYdlPLPGLTLGGGVRYVGSRYADAANTVKLPSYTRFDAGASYRLNKNLTLRLNVNNLTDKRYYASA---- 617
                        730       740
                 ....*....|....*....|....*
gi 518505941 783 vpeNGIITARTINGRTASVGLRYQF 807
Cdd:COG4774  618 ---YGSGYVTPGAPRTVLLSASYRF 639
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
17-807 1.06e-42

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 165.84  E-value: 1.06e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  17 LAISSTTAIAQQTDNENDVAAEASASTGlgfERILVTGAVSRNQSVMQSSVSVST---------------LTFEDIDVSS 81
Cdd:COG4773    5 LAGSGLAAAAAGALAQAAAAAAAEATTL---PEVTVTGTAEGTGGYTAKSSSTATkldtplretpqsvsvVTRQLIEDQG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  82 PRSTAEIFRMLPGVRSESTGGEGNANIAVRGLPVAaggakflTLQEDGLPVLQFGDIAFGNADIfvradstmARLDVIRG 161
Cdd:COG4773   82 ATTLDDALRNVPGVTVSSYDGGGRDSFSIRGFSID-------NYLRDGLPLGGFGGGQPDTANL--------ERVEVLKG 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 162 GSASTAASNSPGGIINFISKT-GEHQGGSIAISSGlNYDQFRTDFEFGGDINND--MRFHFGGFVRQGEGVRDpGYQGER 238
Cdd:COG4773  147 PAGLLYGAGSPGGLVNLVTKRpTAEPQGEVSLSAG-SWDTYRATADVGGPLNEDgtLRYRLNAAYEDGDSFRD-GVDNRR 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 239 G-------YQIKANVTKEFSAGYvrvyakhlndraasympmpMYADGSSVPGYDAQKDTLqsVYLTQTVRLNGDNqisrg 311
Cdd:COG4773  225 TliapsldWDLTDDTTLTLGAEY-------------------QDDDSTGDRGFLPLDGTL--LDLPRSTNLGEPW----- 278
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 312 dvrNGMNPKVDSFGIEAQFDLDENWTLDNRFRISDVSGNFITLFPAEVGNAqgiadsiagNNSTLT-YAVGPQAGQNYTA 390
Cdd:COG4773  279 ---DYYDTETTTLFAELEHRFNDDWSLRANARYSDSDRDGRSAYAYGAPDA---------ATGTLTrYASARDGDSRSDS 346
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 391 ADAMRIHTFDveindFGSMVNDLklarsfgdvdvTFGYYMADQTISMSWlwnsylmalkgNNAELLNVNAADGTAFSEqg 470
Cdd:COG4773  347 LDANLNGKFE-----TGGLEHTL-----------LVGADYSRYDSDSDS-----------ATAGTINIYNPVYGNLPE-- 397
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 471 qlaygvPFWGNccqRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGTYAGASQSSRDmnNDGAISqieqsvsg 549
Cdd:COG4773  398 ------PDFDA---SDTDTTTRQTGLYAQDQISLTDrLSLLLGGRYDWYETDSTNRLGGSTTSY--DDSAFT-------- 458
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 550 idlanpqlvnyswgynsYSAGANYQFNRDWAMFGRISKGARANADRllfgkvNADGSVAreDAIdEVKQYEIGSKSRHGN 629
Cdd:COG4773  459 -----------------PRAGLVYDLTPGLSLYASYSESFEPQSGA------DNNGNPL--DPE-TGKQYEAGVKGELFD 512
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 630 LNLFATLFFAETDEQNFeATTQLFFDRVYKA------KGIELESSYRIGD-FDFRGSVTFTDAEISSDALNPD--VVGNT 700
Cdd:COG4773  513 GRLNATLAVFDITQKNV-ATTDPDNPNFYVQvgevrsRGVELELSGELTPgLNLIAGYTYTDAKITKDADALEgkRLTNV 591
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 701 PRRQAdmiySLLARYTMDNAQ-----VGISLVGTTDSYAQDNNDLKFSGYTQLNAFANYELAENLTLSLNVNNLFDTIGI 775
Cdd:COG4773  592 PRHTA----SLWTTYRFPSGAlkglgLGGGVRYVGERYGDAANTFTLPSYTLVDAGARYDLGKNWTLQLNVNNLFDKKYY 667
                        810       820       830
                 ....*....|....*....|....*....|..
gi 518505941 776 TEAeqgsvpeNGIITARTINGRTASVGLRYQF 807
Cdd:COG4773  668 ASS-------GSRGYVYYGAPRNVRLSLSYKF 692
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
75-772 6.53e-40

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 156.91  E-value: 6.53e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  75 EDIDVSSPRSTAEIFRMLPGVRSESTGGeGNANIAVRGLPVAAGGAKFLTlqeDGLPVlqfGDIAFGNADIFVRADSTMA 154
Cdd:COG1629   28 EQLEDQPATDLGDLLRRVPGVSVTSAGG-GAGQISIRGFGGGGNRVLVLV---DGVPL---NDPSGGDGGLSYIDPEDIE 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 155 RLDVIRGGSASTAASNSPGGIINFISKTGEH-QGGSIAISSGlNYDQFRTDFEFGGDiNNDMRFHFGGFVRQGEGVRDPG 233
Cdd:COG1629  101 RVEVLRGPSSALYGSGALGGVINIVTKKPKDgKGGEVSASYG-SYGTYRASLSLSGG-NGKLAYRLSASYRDSDGYRDNS 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 234 YQgeRGYQIKANVTKEFS-AGYVRVYAKHLNDRaasympmpmyadgssvpgYDAQKDTLQSVYLTQTVRLNGDNQISRGD 312
Cdd:COG1629  179 DS--DRYNLRAKLGYQLGdDTRLTLSASYSDSD------------------QDSPGYLTLAALRPRGAMDDGTNPYSNDT 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 313 VRNgmnpKVDSFGIEAQFD-LDENWTLDNRFRISDVSGNFitlfpaevgnaqgiadsiaGNNSTLTYAVGPQAGQNYTAa 391
Cdd:COG1629  239 DDN----TRDRYSLSLEYEhLGDGLKLSASAYYRYDDTDL-------------------DSDFTPTPADGGTLEQTDFD- 294
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 392 damrihtfdveiNDFGSMVNDLKLARSFGD-VDVTFGYYMADQTISMSWLWNSYLMALKGNNAEllnvnaadgtafseqg 470
Cdd:COG1629  295 ------------NRTYGLELRLTYDLGFGGkHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTS---------------- 346
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 471 qlaygvpfwgnccQRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGTYAGASQSSRDmnndgaisqieqsvsg 549
Cdd:COG1629  347 -------------GADDDGTTTSLALYAQDTYKLTDkLTLTAGLRYDYVSYDVDDTVTGTDSAS---------------- 397
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 550 idlanpqlVNYSWGYNSYSAGANYQFNRDWAMFGRISKGARANADRLLFGKVNADGSVAREDAIDE-VKQYEIGSKSRH- 627
Cdd:COG1629  398 --------GSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYSVGNPDLKPEtSTNYELGLRYRLl 469
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 628 -GNLNLFATLFFAETDeqNFEATTQLFFDRVY----------KAKGIELESSYRIGD-FDFRGSVTFTDAEISSD-ALNP 694
Cdd:COG1629  470 dGRLSLSLALFYSDVD--NEILSVPLPNDSGFstyytnagkaRSYGVELELSYQLTPgLSLNASYSYTDAKFDDDtDGSA 547
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 695 DVVGNTPRRQADMIYSLLARYT-MDNAQVGISLVGTTDSYAQDNNDLKF-SGYTQLNAFANYELAENLTLSLNVNNLFDT 772
Cdd:COG1629  548 DLDGNRLPGVPPLTANLGLTYEfPGGWSLGLGVRYVGDRYLDDANTQGApGGYTLVDLGAGYRFGDNLTLSLGVDNLFDK 627
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
75-807 2.87e-36

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 145.67  E-value: 2.87e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  75 EDIDVSSPRSTAEIFRMLPGVRSESTGGEGNANIAVRGLpvaagGAKFLTLQEDGLPVLQFGDIAFGNADIFvraDSTMA 154
Cdd:cd01347    8 EDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISIRGF-----GPDRTLVLVDGLPLASSNYGRGVDLNTI---PPELI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 155 -RLDVIRGGSASTAASNSPGGIINFISKTGEHQ-GGSIAISSGLN--YDQFRTDFEFGGDI--NNDMRFHFGGFVRQGEG 228
Cdd:cd01347   80 eRVEVLKGPSSALYGSGAIGGVVNIITKRPTDEfGGSVTAGYGSDnsGSSGGGGFDVSGALadDGAFGARLYGAYRDGDG 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 229 VRDPGYQGER------------GYQIKANVTKEFSAGYvrvyAKHLNDRAasYMPMPMYADGSSVPGydaqkdtlqsvyl 296
Cdd:cd01347  160 TIDGDGQADDsdeerynvagklDWRPDDDTRLTLDAGY----QDQDADGP--GGTLPANGTGSSLGG------------- 220
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 297 TQTVRLNGDNQISRGDVRNGMNpkvdSFGIEAQFDlDENWTLDNRFRISDVSGNFITLFPAEVGNAQGIADSIAGNNSTL 376
Cdd:cd01347  221 GPSSNTNGDRDWDYRDRYRKRA----SLGLEHDLN-DTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSER 295
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 377 TYavgpqagqnytaadamRIHTFDVEINdfgsmvndlklaRSFGDVDVTFgyymadqtismswlwnsylmalkgnnaell 456
Cdd:cd01347  296 DT----------------TQLGFDAGLN------------APFGTGPVAH------------------------------ 317
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 457 nvnaadgtafseqgQLAYGVPFwgnccqRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGTYAGASQSSRDMN 535
Cdd:cd01347  318 --------------TLTLGVEY------RREELDEKQTALYAQDTIELTDdLTLTLGLRYDHYDQDSKDTIAGGTTAKKS 377
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 536 NDgaisqieqsvsgidlanpqlvnyswgYNSYSAGANYQFNRDWAMFGRISKGARANADRLLFGKVNADGSVARED---A 612
Cdd:cd01347  378 YS--------------------------HWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAAVGNpnlK 431
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 613 IDEVKQYEIGSKSRHGN-LNLFATLF--------FAETDEQNFEATTQLFFDRVYKAKGIELESSYRIGD-FDFRGSVTF 682
Cdd:cd01347  432 PEKSKQYELGLKYDPGDgLTLSAALFridikneiVSTPTNTGLGLVTVYVNGGKARIRGVELEASYDLTDgLGLTGSYTY 511
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 683 TDAEISSDALNPDvvGNTPRRQADMIYSLLARYTMDNAQVGISLVGT-----TDSYAQDNNDLKFSGYTQLNAFANYELA 757
Cdd:cd01347  512 TDTEVKRTDGATT--GNRLPGIPKHTANLGLDYELPDEGLTAGGGVRyrgkqYADTANGNNTVKVPGYTLVDLSASYQFT 589
                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|
gi 518505941 758 ENLTLSLNVNNLFDTigiTEAEQGSVPENGIITArTINGRTASVGLRYQF 807
Cdd:cd01347  590 KNLTLRLGVNNLFDK---DYYTSLSVRGSGLYGY-YGPGRTYYLSVSYKF 635
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
35-807 2.56e-35

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 143.14  E-value: 2.56e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  35 VAAEASASTGLgfERILVTGAVSRNQSVMQSSVSVSTLTFEDIDVSSPRSTAEIFRMLPGVRSESTGGEGNA-NIAVRGL 113
Cdd:COG4772   13 AAAAAEAATTL--ETVVVTGSRAAEARLKDVPGSVSVVDREELENQAATSLREVLRRVPGVNVQEEDGFGLRpNIGIRGL 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 114 PvaAGGAKFLTLQEDGLPVlQFGDIAFGNADIFVRADStMARLDVIRGGSASTAASNSPGGIINFISKTGEHQGGSIAIS 193
Cdd:COG4772   91 G--PRRSRGITLLEDGIPI-APAPYGDPAAYYFPDLER-MERIEVLRGAAALRYGPQTVGGAINFVTRTIPTAFGGELRV 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 194 SGLNYDQFRTDFEFGGDINNdmrfhFGGFV----RQGEGVRDP-GYQGER-----GYQIKANVTKEFSAGYVRVYAKhln 263
Cdd:COG4772  167 TGGSFGYRRTHASVGGTVGN-----FGYLVeysrKRGDGFRDNsGFDINDfnaklGYRLSDRQELTLKFQYYDEDAN--- 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 264 draasympmpmyadgssVPGY--DAQKDtlqsvyltqtvrlngDNQISRGDVRNGMNPKVDSFGIEAQFDLDENWTLDNR 341
Cdd:COG4772  239 -----------------TPGGltDAQFD---------------ADPRQSYRPADQFDTRRTQLSLRYEHQLSDNTTLTTT 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 342 FRISDVSGNFitLFPAEVGNAQGIADSIAGNNSTL-TYAVGPQAGQNYTAADAmrihtfdveindfgsmvndlklarsfg 420
Cdd:COG4772  287 AYYNDFSRNW--YIRQNTADPNTPGLGLRGNPRGYrSYGIEPRLTHRFELGGV--------------------------- 337
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 421 DVDVTFGY-YMADQTISMSWlWNSYLMALKGNNAellnvnaadgtafseqgqlaygvpfwgnccQRNYDTQYSTTAPYIN 499
Cdd:COG4772  338 PHTLEVGLrYHREEEDRKQY-VNTYGQGRSGAGL------------------------------RRDRRFSADALAAYAQ 386
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 500 VGWAF-GDWSLDASVRrdngkatgtYAGASQSSRDMNNDGAISQIEQSVSgIDLANPqlvnyswgynsySAGANYQFNRD 578
Cdd:COG4772  387 NRFELtGRLTLTPGLR---------YEHIRRDRTDRYSTRTGGDDSGSNS-YSEFLP------------GLGLLYQLTDN 444
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 579 WAMFGRISKGARANADRLLFGKVNADGSVAREDAidevKQYEIGSKSRHGNLNLF-ATLFFAETDEQNFEATTQLFFDRV 657
Cdd:COG4772  445 LQLYANVSRGFEPPTFGDLAYGNGGNPDLKPEKS----WNYELGTRGRIGNGLSAeVALFYIDYDNELGSCSAAGGDRST 520
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 658 YKA------KGIELESSYRIG-----DFDFRGSVTFTDAEISSDAlNPDVVGN----TPRRQadmiYSLLARYTMDNAQV 722
Cdd:COG4772  521 FTNagetrhQGLELALDYDLLkggglGLPLFAAYTYTDAEFTSDF-GPVFAGNrlpyVPRHQ----LTAGLGYEHGGWTA 595
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 723 GISLVGTTDSYAQDNNDLKF------SGYTQLNAFANYELAENLTLSLNVNNLFDTIGITeaeqgSVPENGIITARTING 796
Cdd:COG4772  596 NLNGRYVSEQFTDAANTVADgsfgkiPSYTVLDLSASYDFGKNLSLFAGVNNLFDKRYIA-----SRAPNYAAGIRPGPP 670
                        810
                 ....*....|.
gi 518505941 797 RTASVGLRYQF 807
Cdd:COG4772  671 RTVYAGLRLKF 681
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
71-807 3.22e-24

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 108.27  E-value: 3.22e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941   71 TLTFEDIDVSSPRSTAEIFRMLPGVRSESTGGEGN-ANIAVRGLPVAAGGAKFLTlqeDGLPVLqfgdiafGNADIFVRA 149
Cdd:TIGR01783   8 VITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQfGNITIRGFGLEVDIDNVYL---DGVPLL-------SRGNLAIVD 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  150 DSTMARLDVIRGGSASTAASNSPGGIINFISKTG-EHQGGSIAISSGlNYDQFRTDFEFGGDINNDmrFHFGGFV----R 224
Cdd:TIGR01783  78 PAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPqDEPKGSVTFGAG-TRSGYRTAFDLGGPLGAD--GTFRGRLngarQ 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  225 QGEGVRDpgYQGER--------GYQIKANVTKEFSAGYvRVYAKHLNDRAASYMPmpmyadgsSVPGYDAQKDTLQSvyl 296
Cdd:TIGR01783 155 DGDSFYD--GAGEEtrlgatatDWQLDDRTLLRLGAYY-QKERDRGGYGGLPASG--------GTSGRDLSSDRYLG--- 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  297 TQTVRLNGDNQISRGdvrngmnpkvdsfGIEAQFDLDENWTLDNRFRISDVSGNFITLFPAEVGNAQGIADSIAGNNSTL 376
Cdd:TIGR01783 221 TSSNRNYDDREYLSY-------------GLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVNVK 287
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  377 TYAVGPQAGQNytaadaMRIHTFDVEIndfgsmvndlklarsfgdvdvTFGYYMADQTISMSWLWNSYLMALKGNNAELL 456
Cdd:TIGR01783 288 QDRVQIDAGLD------GEFETGPIEH---------------------DLLLGVSYGQRTTNRFNNTGYPSDNIYSLTAT 340
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  457 NVNAADGTAFSEQGQLaygvpfwgnccqrnYDTQYSTTAPYINVGWAFGDWSLDASVRRDNGKatgtyagasqssRDMNN 536
Cdd:TIGR01783 341 SSARTDIGDSPKDRAL--------------SSTTKALNGVALQRILLADKWTLTLGGRYDSVD------------VKSNN 394
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  537 DGAISQIEQSVSgidlanpqlvNYSWgynsySAGANYQFNRDWAMFGRISKGARANADRLLFGKVNADGSVAredaiDEV 616
Cdd:TIGR01783 395 GVAGSTGKRDDS----------QFTP-----SLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGNSGDILEP-----EKG 454
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  617 KQYEIGSKSRHGNLNLF-ATLF---FAETDEQNFEATTQLFFDRVYKAKGIELESSYRIGD-FDFRGSVTFTDAEISSDA 691
Cdd:TIGR01783 455 KNYELGVRYDLGDSLLAtAALFritKDNQLVQDPVNGTFSVNAGKTRNRGVELEARGYLTPgLSLSAGYTYTDAEFTEDT 534
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  692 lNPDVVGNTPRRQADMIYSLLARY---TMDNA-QVGISLVGTTDSYAQDNNDLKFSGYTQLNAFANYELA--ENLTLSLN 765
Cdd:TIGR01783 535 -NGDTQGNTVPFVPKHTASLWASYappVGDNGlTLGGGVQYTGKAYVDGGNTGKVPSYTVVDLSVRYDLTkkKNLTLALN 613
                         730       740       750       760
                  ....*....|....*....|....*....|....*....|..
gi 518505941  766 VNNLFDTIGITEAEQGSvPENGIITARtinGRTASVGLRYQF 807
Cdd:TIGR01783 614 VNNLFDRDYYTSGYRWG-PSAYIYPGA---PRTVGLSVSYDF 651
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
398-806 2.37e-22

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 101.39  E-value: 2.37e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  398 TFDVEINDFGSMVNDLKLARSFGDVDVTFGYYMADQTISMSWLWNSYLMALKGNNAELLNVNAADGTAFSEQGQLAYGVP 477
Cdd:pfam00593  66 GYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLD 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  478 F-------------WGNCCQRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGTYAGASQSSrdmnndgaisqi 543
Cdd:pfam00593 146 YrrldddaydpydpANPSSSSYSDTTTDSYGLYLQDNIKLTDrLTLTLGLRYDHYSTDGDDGNGGGDN------------ 213
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  544 eqsvsgidlanpqlVNYSWGYNSYSAGANYQFNRDWAMFGRISKGARA-NADRLLFGKVNADGSVAREDAID----EVKQ 618
Cdd:pfam00593 214 --------------FSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRApSLGELYGSGSGGGGGAVAGGNPDlkpeTSDN 279
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  619 YEIGSKSRHGNLNLFATLFFAE-TDEQNFEATTQLFFDRVY--------KAKGIELESSYRI-GDFDFRGSVTFTDAEis 688
Cdd:pfam00593 280 YELGLKYDDGRLSLSLALFYIDiKNLITSDPDGPGLGGTVYtytnvgkaRIRGVELELSGRLwGLGLSGGGYTYTDAD-- 357
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  689 sDALNPDVVGNTPRRQADMIYSLLARYTMDN----AQVGISLVGTTDSYAQD-NNDLKFSGYTQLNAFANYELAENLTLS 763
Cdd:pfam00593 358 -DDADADDTGNPLPNVPRHTANLGLTYDFPLggwgARLGARYVGSGERRYGDaANTFKTPGYTLVDLSAGYRLNKNLTLR 436
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 518505941  764 LNVNNLFDtigiTEAEQGSVPENGIITARTINGRTASVGLRYQ 806
Cdd:pfam00593 437 LGVNNLFD----KYYKRYYSSGGGNLGGYPGPGRTFYLGLSYK 475
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
71-807 1.39e-17

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 87.47  E-value: 1.39e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941   71 TLTFEDIDVSSPRSTAEIFRMLPGVRSESTGGEGNANIAVRGLpvaagGAKFLTLQEDGLP-VLQFGDIAFGNADIFVRA 149
Cdd:TIGR01786  27 VISREQLKSQQVRNLRDLLRYEPGVSVVEGGRGGSQGINIRGL-----DKNRVAVLVDGIRqNTSYGGQGSTFYAINSID 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  150 DSTMARLDVIRGGSASTAASNSPGGIINFISKT-------GEHQGGSIAISSGLNydqfrtdfefggdiNNDMRFHFGGF 222
Cdd:TIGR01786 102 PELIKSIEIVKGASSSLYGSGALGGVVAFRTKDaadllkpGKDLGGLSKLGYSSA--------------NNRFTQSVAAA 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  223 VRQGegvrdpgyqgergyqikaNVTKEFSAGYvrvyaKHLNDraasympmpmyadgssvpgYDAQKDTlqsvyltqtvrl 302
Cdd:TIGR01786 168 GRND------------------DVDALVQATY-----RRGHE-------------------LKNGNKA------------ 193
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  303 NGDNQISRGDVrNGMNPKVDSFGIEAQFDLDENWTLDNRFRISDVSGNfitlfpaEVGNAQGIADSIAGNNSTLTYAVGP 382
Cdd:TIGR01786 194 NIGNESKRSKP-NPSDYKSQSFLAKLGWQLNDAHRLGLSLEYTQTDYD-------EPEMTNTSYLTKPLGAPLLSSTVVL 265
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  383 QAGQNYtaadaMRIHTFDVEINDFGSMVNDLKLARSFGDVDVTFGYYMADQTISMswlWNSYLMALK-GNNAELLNVNAA 461
Cdd:TIGR01786 266 GDSKTR-----DRRTGLDYELNPDNSWLDTVKLALDKQYIQLYNYLNATSASDYP---GVDKNGRYKdKYDYYTLGFDTN 337
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  462 DGTAFSEQGQ-LAYGV---------PFWGNCCQRNYDTQYSTTAPYINVG-----------WAFGDW-SLDASVRRDNGK 519
Cdd:TIGR01786 338 NKIEFSVHSLsLTYGLdrfkdkvstGDSRRNLPTAAYNLYGYEGENRPVKgsnfglflqdnIKLGDWlSLSAGLRYDHYK 417
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  520 ATGtyagasqSSRDMNNDGAISqieqsvsgidlanpqlvnYSWGYNSYSAGANYQFNRDWAMFGRISKGARA-NADRLLF 598
Cdd:TIGR01786 418 TDP-------KADESKDYGAIS------------------KTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRApSFDELYG 472
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  599 GKVNADGSVAR---------EDAidevKQYEIGSKSRHGNLNLFATLFfaETDEQNFEATTQLFFDRVYKA--------- 660
Cdd:TIGR01786 473 TGAHPGGGPYTflpnpnlkpETS----KNWEIGINLHFDQLDFKVSYF--RNDYKDFIDLGIGVTAKGNMAqvgsntitn 546
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  661 ---------KGIELESSYRIGDFDF--------------RGSVTFTDAEIssDALNPD-VVGNTPRRQADMIYSLLARYT 716
Cdd:TIGR01786 547 yvnidnariRGIELSGRYDLGSFFSgpdgwtttlkygytKGKDSDTNPWL--NAITPLkVVLGLGYDHPDEKWGVGLTLT 624
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  717 MDNAQ--VGISLVGTTDSYAQDNNDLKFSGYTQLNAFANYELAENLTLSLNVNNLFDTIGITEAEQGSVPENGiiTARTI 794
Cdd:TIGR01786 625 FSGAKdaVDAYATYYENGEAAKAGPLRTPSYTVVDLYGYYKPNKNLTLRFGVYNLLDRKYTTWESARQAGPLA--TGYTA 702
                         810
                  ....*....|...
gi 518505941  795 NGRTASVGLRYQF 807
Cdd:TIGR01786 703 PGRNYKASVEYKF 715
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
14-763 3.65e-17

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 85.68  E-value: 3.65e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  14 AVSLAISSTTAIAQQTDNENDVAAEAsastglgFERILVTGAvSRNQSVMQSSVSVSTLTFEDIDVSSPRSTAEIFRMLP 93
Cdd:COG4771    1 LLLASLLLLLALAAQAADALAEDATE-------LEEVVVTAT-RTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLP 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  94 GVRSESTGGEGNAN-IAVRGLpvaaGGAKFLTLQeDGLPVlqfGDIAFGNADIFVRADSTM-ARLDVIRGGSASTAASNS 171
Cdd:COG4771   73 GVSVTRSGGRGGSSgISIRGL----GGDRVLVLI-DGVPV---NNPALGGGGDLSYIPPDDiERIEVIRGPASALYGSDA 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 172 PGGIINFISKTGEHQG-GSIAISSGLNYD-QFRTDFEFGGDiNNDMRFHFGGFVRQGEGVRDPGYQGERGYqikanvtke 249
Cdd:COG4771  145 IGGVINIITKKPTDELeGSVSLGYGSNGNgTYSGSLSLGGP-GDKLSFLLSGSYRDRDGYLDYRNGGFVGN--------- 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 250 fsagyvrvyakhlndraasympmpmyadgssvPGYDAQkdtlqsvyltqtvrlngdnqisrgdvrngmnpkvdSFGIEAQ 329
Cdd:COG4771  215 --------------------------------SGYERY-----------------------------------NLNAKLG 227
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 330 FDLDENWTLDNRFRISDVSGnfitlfpaevgnaqgiadsiagnnstltYAVGPQAGQNYTAADAMRIHTFDVEINDFGsm 409
Cdd:COG4771  228 YRLSDNHRLSLSGGYSRQDR----------------------------DGGPPTLGDTEISSDNAGDRDTTTDRGNYS-- 277
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 410 vndLKLARSFGD-VDVTFGYYMADQTiSMSWLWNSYLMALKGNNAELLNVNAADGTAFSEQGQLAYGVPFW-----GNCC 483
Cdd:COG4771  278 ---LRYNGDLGDnLDLSLYYSRTDRD-STNGSLGGSTGSFSDSDDTTYGLELDLTYPLGGNHTLTLGAEYRyddldSSSF 353
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 484 QRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNgkatgtyagasQSSRDMNNDGAIsqieqsvsgidlanpqlvnysw 562
Cdd:COG4771  354 LGGADASRDTYGLFAQDEWKLTDkLTLTAGLRYDY-----------YSTFGASNYTAF---------------------- 400
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 563 gynSYSAGANYQFNRDWAMFGRISKGARA--NADRLLFGKVNADGSVAREDAID--EVKQYEIGSKSRHGNLNLFATLFF 638
Cdd:COG4771  401 ---SPRLGLRYDLSDNLTLRASYGRGFRApsLAELYGSGTGTPGRYVLGNPDLKpeTSDNYELGLEYRLGNGGLSLSLTG 477
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 639 AETDEQNF--------EATTQLFFDRVYKA--KGIELESSYRIGD-FDFRGSVTFTDAEISSDALNPDvVGNTPRRQAdm 707
Cdd:COG4771  478 FYTDIKDLivlvpvgpGPGDVLQYENVGKArtYGLELELKYRLGKgLTLTASYTYLDSKIDDGDTGEP-LPNVPPHKA-- 554
                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 708 iySLLARYTMDNAQVGISLV----GTTDSYAQDNNDLKFSGYTQLNAFANYELAENLTLS 763
Cdd:COG4771  555 --NLGLDYRLPKWWLLLLLTryygGRYVTPPSGRLEGYTPGYTLLDLRASYKLTKNLTLS 612
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
47-807 9.37e-15

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 78.20  E-value: 9.37e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941   47 FERILVTGAVSRNQSVMQSSVSVsTLTFEDIDVSSPRSTAEIFRMLPGVRSESTGGEGNANIAVRGLpvaagGAKFLTLQ 126
Cdd:TIGR01785   1 LDTVTVTATRTRQVLSEAPASVS-VISGEQIESKQANNLADALNTVPGVDVTGGGRPPGQSINIRGL-----QDNRVLVV 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  127 EDGLPvlQFGDIAFGNADIFVRADSTMARLDVIRGGSASTAASNSPGGIINFISKT-------GEHQGGSIAISSGLNYD 199
Cdd:TIGR01785  75 VDGAR--QNYQRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDaadllrpGQLFGGLAKLSYGSNNN 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  200 QFRTDFEFGGDINNDMRFHFGGFVRQGEGVRdPGYQGERGYQikANVTKEFSA-GYVRVYAKHLNDRAASYmpmpmyadg 278
Cdd:TIGR01785 153 SFGGSVAVAGRLDDNLDALVAATYRDGGNYR-NGNKEEATNS--AYVQKNLLAkLGWQLDDAQRLEFSYFT--------- 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  279 ssvpgYDAQKDTLQSVYLTQTVRLNGDNQISRGDVRNgmnpkvDSFGIEAQFDLDENWTLDNRFrisdvsgnfitlfpae 358
Cdd:TIGR01785 221 -----TEGSLDEAQNSGPGTEYVLGSSSTLLASSTRD------RSATLTYNWTPEDNPWLDATA---------------- 273
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  359 vgnaqgiadSIAGNNstlTYAVGPQAGQNYTAADAMRIHTFDVEINDfGSMVNDLKLARSFGDVDvtfgyYMADQTISMS 438
Cdd:TIGR01785 274 ---------SLYYNR---TENDNDRSARGVGREEGYQYTTYGATLQN-TSRFDVASWSTLTYGVD-----WMKDKRRTES 335
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  439 WlwnsylmalKGNNAELLNVNAADGTAFSEQGQLAYGVPFWGnccqrnydtqysttapyinvgwafGDWSLDASVRRDNG 518
Cdd:TIGR01785 336 F---------DPNSVTTIVPNPPSAKEYFFGLFLQDNIPLLD------------------------DRLTLSAGLRYDHY 382
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  519 KATG-TYAGASQSSRDmnnDGAISQieqsvsgidlanpqlvnyswgynsySAGANYQFNRDWAMFGRISKGARA-NADRL 596
Cdd:TIGR01785 383 KLSPkTTADTEAVDRS---YSRWSP-------------------------SLGLSYKPVDWLTLYASYSQGFRApSIDEL 434
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  597 LFGKVNADGS-----VAREDAIDEV-KQYEIGSKSRHGN-------LNLFATLFFaeTDEQNFEATTQLFFDRV------ 657
Cdd:TIGR01785 435 YGTGDHPGTPggytfAPNPNLKPETsKTWELGANLSFDNllldndqLQFKVAYFY--NDVKDFIDLTIGVTDNVtagmnn 512
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  658 ---------YKAKGIELESSYRIGDFDFRGSVTFTDAEISS-----DALNPD---VVGNTPRRQADMIYSLLARYTMDNA 720
Cdd:TIGR01785 513 itqyvnidgARIRGIEASASYDAGLWATGLSYGYTIGKDQNtnqwlSNIPPLklvVTVGYRFPDRRLDLGAKAAYYERQS 592
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  721 QVGISLVGTTdsyaqdNNDLKFSGYTQLNAFANYELAE--NLTLSLNVNNLFDTIGIteaeqgsvPENGIITARTinGRT 798
Cdd:TIGR01785 593 ESPTTEDVAA------NGLLTTPGYTVVDLYATYQPNAvkGLTVRFGVNNLTDRKYT--------PAQSVPGAGP--GRN 656

                  ....*....
gi 518505941  799 ASVGLRYQF 807
Cdd:TIGR01785 657 FKGSVKYQF 665
PRK14050 PRK14050
TonB-dependent siderophore receptor;
87-771 1.27e-12

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 71.37  E-value: 1.27e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  87 EIFRMLPGVRSESTGGEGNAN-IAVRGLPVAAGGAkFLtlqeDGLPVLQFGdiaFGNADIfvraDSTM-ARLDVIRGGSA 164
Cdd:PRK14050 102 EALRYTPGVLSQPFGTDGDTDwFYIRGFDATQTGV-FL----DGLNLFSYG---FGGFQI----DPFMlERVEVLKGPAS 169
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 165 STAASNSPGGIINFISK--TGE-HQGGSIAISsglNYDQFRTDFEFGGDINND--MRFHFGGFVRQGEGVRDpGYQGERG 239
Cdd:PRK14050 170 VLYGGSNPGGIVNMVSKrpLDEpLYYTEIGIN---SYGNAFTGFDVGDKLSDDgtVRYRVTGKVAGGDNYSD-YSEDLRG 245
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 240 YqIKANVTKEFSAGY---VRVYAKHLNDRAASYMPMPMYADGSSVPGYDAQKDtlqsvyltqtvRLNGDNQISRGDVRNG 316
Cdd:PRK14050 246 F-IMPQITYAPDDATsltVYGYLSGLDQVHVGNGFLPYVGTVVDAPFGKIDRD-----------AFYGEPDIDNGSYAQQ 313
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 317 MnpkvdsFGIEAQFDLDENWTLDNRFRISDVSGNFITLFP-AEVGNAQGIADSIAGNNSTLTYAVGPQAGQNYTAADAMR 395
Cdd:PRK14050 314 M------LGYEFSHEFDNGWTFSQNARYGHLHKHEKGPYTyGYVGGATGLPDPTGPDYMLNRIGFEHRSKVDSFSIDNRL 387
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 396 IHTFDVeindfGSMVNDLKLArsfgdvdVTFGYYMADQtismswlwnsyLMALKGNNAellnVNAADGTafseqgqlaYG 475
Cdd:PRK14050 388 EGEFDT-----GALTHNLLFG-------LDYKYYRLDQ-----------VQACCGATP----ISATNPV---------YG 431
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 476 VPFWGNCCQRNYDTQYSTTAPYINVGWAFGD-WSLDASVRRDNGKATGtyAGASQSSRDmNNDGAISQieqsvsgidlan 554
Cdd:PRK14050 432 TTQGANFVYLDQILTQQQIGIYAQDQIRFGDgWLVTLNGRYDYVDTDS--DARIGTSYE-SNDGALSG------------ 496
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 555 pqlvnyswgynsySAGANYQFnrDWAMFGRISKGARANAdrlLFGkVNADGSVAREDaidEVKQYEIGSKSRHGNLN--L 632
Cdd:PRK14050 497 -------------RAGLAYEF--DNGLTPYVSAATFFNP---LVG-TLASGPPLKPE---EGEQYEAGIKYEPSFIDglI 554
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 633 FATLFfaETDEQNFEATTQLFFDRV----YKAKGIELESSYRIGD-FDFRGSVTFTDAEISSDAlNPDVVGNTPRRQADM 707
Cdd:PRK14050 555 TASVF--QITKKNVTVTDPLTFASTqlgeVRSRGFELEGKVNLDDnWKALASFTYTDLEITEDA-NPSLIGNSPYLVPET 631
                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 518505941 708 IYSLLARYTM-DNAQVGISLVGTT----DSYAQDNNDLKFSGYTQLNAFANYElAENLTLSLNVNNLFD 771
Cdd:PRK14050 632 QASLWLDYAVtDGAFEGVSLGAGVryqgESWADEANTLKVPAATLFDAAIRYE-KNDWGASLNVANLFD 699
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
71-175 1.01e-10

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 59.20  E-value: 1.01e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941   71 TLTFEDIDVSSPRSTAEIFRMLPGVRSESTGGEGNANIAVRGLpvaagGAKFLTLQEDGLPVLQFGDIAFGNADIFVrad 150
Cdd:pfam07715  11 VVTAEDIEDQGATNLADALRGVPGVSVSSGGGGGGSSISIRGF-----GSNRVLVLVDGVPLNSGGGGSVDLNSIDP--- 82
                          90       100
                  ....*....|....*....|....*
gi 518505941  151 STMARLDVIRGGSASTAASNSPGGI 175
Cdd:pfam07715  83 EDIERVEVLKGPASALYGSGAIGGV 107
PRK10044 PRK10044
ferrichrome outer membrane transporter; Provisional
73-771 2.99e-10

ferrichrome outer membrane transporter; Provisional


Pssm-ID: 236643 [Multi-domain]  Cd Length: 727  Bit Score: 64.01  E-value: 2.99e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  73 TFEDIDVSSPRSTAEIFRMLPGVrseSTGGEGNAN----IAVRGL-PVAAGGAKFLtlqeDGLPvLQfGDiafgNADIFV 147
Cdd:PRK10044  87 TAEEMALHQPKSVKEALSYTPGV---SVGTRGASNtydhLIIRGFaASGQSQNNYL----DGLK-LQ-GN----FYNDAV 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 148 RADSTMARLDVIRGGSASTAASNSPGGIINFISK--TGEHQGgSIAISSGlNYDQFRTDFEFGGDINND--MRFHFGGFV 223
Cdd:PRK10044 154 IDPYMLERAELMRGPVSVLYGKSNPGGLLNMVSKrpTTEPLK-EVQFKMG-TDNLFQTGFDFSDALDDDgvYSYRLTGLA 231
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 224 RQGEGVRDpgYQGERGYQI----------KANVT------KEFSAGYVrvyakhlndraaSYMPmpmyADGSSVPGYDAQ 287
Cdd:PRK10044 232 RSANAQQK--GSEEQRYAIapsftwrpddKTNFTflsyfqNEPETGYY------------GWLP----KEGTVEPLPNGK 293
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 288 KdtlqsvYLTQTVRLNGDNQISRgdvrngmNPKVDSFGIEAQFDldENWTLDNRFRISDVSGNFITLFPAEVGNAQG--I 365
Cdd:PRK10044 294 R------LPTDFNEGAKNNTYSR-------NEKMVGYSFDHEFN--DTFTVRQNLRYAENKTSQRSVYGYGVCSDKGhyL 358
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 366 ADSIAGNNSTL-TYAVGPQAGQNYTAADAMriHTFDVEInDFGSMVNDlklarsfgdVDVTFGYymaDQTISMSWLW-NS 443
Cdd:PRK10044 359 NRGYVVDDEKLqNFSVDTQLQSKFATGDVD--HTLLTGV-DFMRMRND---------INAWFGY---ADSVPLLNLYgPV 423
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 444 YLMALKGNNAELLNV-NAADGTAFSEQGQLAygvpfWGNccqrnydtqysttapyinvgWAFG-----DWSLDASVRRDN 517
Cdd:PRK10044 424 NTDFDFNANSGPYQIlNKQKQTGLYVQDQAE-----WDK--------------------WLVTlggryDWADQSSLNRVN 478
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 518 GkatgtyagasqsSRDMNNDGAisqieqsvsgidlanpqlvnYSWgynsySAGANYQFNRDWAMFGRISKG----ARANA 593
Cdd:PRK10044 479 G------------TTDKRDDKQ--------------------FTW-----RGGVNYLFDNGITPYFSYSESfepsSGTGK 521
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 594 DRLLFgkvnaDGSVAredaidevKQYEIGSKSRHGNLNLFATL-FFAETDEQNFEATTQLFFDRV----YKAKGIELESS 668
Cdd:PRK10044 522 DGNIF-----APSKG--------KQYEAGVKYVPKDRPIVVTGaVYQLTKTNNLTADPENSFFSVqggeIRARGVELEAK 588
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 669 YRI-GDFDFRGSVTFTDAEISSDALnpdVVGNTPRRQADMIYSLLARYTM-DNAQVGISL------VGTtdSYAQDNNDL 740
Cdd:PRK10044 589 AALsANVNVTGSYTYTDAEYTTDTT---YKGNTPAQVPKHMASLWADYTFfDGPLSGLTLgtggryTGS--SYGDPANSF 663
                        730       740       750
                 ....*....|....*....|....*....|....*
gi 518505941 741 KFSGYTQLNAFANYELAE-NL---TLSLNVNNLFD 771
Cdd:PRK10044 664 KVGSYTVVDALVKYDLARfGMagsSVALNVNNLFD 698
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
71-327 3.84e-10

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 61.43  E-value: 3.84e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  71 TLTFEDIDVSSPRSTAEIFRMLPGVRSESTGGEG-NANIAVRGLpvaaGGAKFLTLqEDGLPV--LQFGDIAFGNADIfv 147
Cdd:COG4206   21 VIDAEELERSGATSLADALRRVPGVQVSSSGGPGsAASISIRGL----GSNQTLVL-IDGVPLndPSLGGVDLSLIPP-- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 148 radSTMARLDVIRGGSASTAASNSPGGIINFISKTG-EHQGGSIAISSGlNYDQFRTDFEFGGDINN-DMRFHFGGFVRQ 225
Cdd:COG4206   94 ---DDIERIEVLKGAASALYGSDAIGGVINITTKKGkKGFKGSVSASYG-SFGTRRLSASLSGGAGKfSYSLSASYRRSD 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 226 GEGVRDPGYQGERGYQ---IKANVTKEFSAGY-VRVYAKHLNDRAASYMPMPMYADGSSVPGYDAQKDTLQSVYLTQTVR 301
Cdd:COG4206  170 GYRYNDPDLRNNDGYEntsLNARLGYKLGDNGsLSLSGGYSDSERGYPGAVGSDRNLRLSLSLEYKLSDGWSLLLLAYYY 249
                        250       260
                 ....*....|....*....|....*.
gi 518505941 302 LNGDNQISRGDVRNGMNPKVDSFGIE 327
Cdd:COG4206  250 YDRDYEDGGGDSAGTSNTDGARAGLS 275
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
11-259 2.86e-07

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 54.27  E-value: 2.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  11 LALAVSLAISSTTAIAQQTDNENDVAAEASastglgFERILVTGA--------VSrnqsvmqssvsvsTLTFEDIDVSSP 82
Cdd:PRK13524   8 LALLVNLGIYGVAQAAEAEDAKTDDTPASH------EDTIVVTAAeqnlqapgVS-------------TITAEDIRKRPP 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  83 -RSTAEIFRMLPGVR---SESTGGEGN-ANIAVRGLpvaaGGAKFLTLQeDGLPVLQFGDIAFG-NADIFVRADST---- 152
Cdd:PRK13524  69 aNDVSEIIRTMPGVNltgNSTSGQRGNnRQIDIRGM----GPENTLILI-DGKPVSSRNSVRYGwRGERDTRGDTNwvpp 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 153 --MARLDVIRGGSASTAASNSPGGIINFISK--TGEHQGgsiAISSGLNYDQF-------RTDFEFGGDINNDMRFH-FG 220
Cdd:PRK13524 144 emIERIEVLRGPAAARYGNGAAGGVVNIITKkpTGEWHG---SWNTYFNAPEHkaegatkRTNFSLSGPLGDELSFRlYG 220
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 518505941 221 GF----------------VRQG----------EGVRDPGYQGERGYQIKANVTKEFSAGYVR---VYA 259
Cdd:PRK13524 221 NLnktqadawdinqghqsARTGsyagtlpagrEGVINKDINGLLRWDFAPLQSLELEAGYSRqgnLYA 288
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
645-807 1.19e-06

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 52.34  E-value: 1.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  645 NFEATTQLFFDRVYKAKGIELESSYRIG-------DFDFRGSVTFTDAEISSDALNPDVVGNTPRRQADMIYSLLARYTM 717
Cdd:TIGR01782 675 GVLVSRPVNGGKAGKIRGVELGYQQTFDflpgplsGFGVQANYTYVDSEADPSVDGVQRRKLPLPGLSKNTANATLYYEK 754
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  718 DNAQVGIS------LVGTTDSYAQDNNDLKFSGYTQLNAFANYELAENLTLSLNVNNLFDTIGITEAEQGSVPENGiita 791
Cdd:TIGR01782 755 GGFSARLSynyrsdYLLDVGGSNINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREY---- 830
                         170
                  ....*....|....*.
gi 518505941  792 rTINGRTASVGLRYQF 807
Cdd:TIGR01782 831 -VETGRTYMLGLRYKF 845
PRK13486 PRK13486
TonB-dependent receptor;
39-197 3.21e-05

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 47.71  E-value: 3.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  39 ASASTGLGFERILVTGAVSRNQSVMQSSVSVSTLTFEDIDVSSPRSTAEIFRMLPGVRSES-TGGEGNANIAVRGLP--- 114
Cdd:PRK13486  16 FSASSIAAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRSVEGVDVESgTGKTGGLEISIRGMPasy 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 115 -------VAAGGAKFLTlqEDGLPVLQFGdiafgnadiFVRADSTMARLDVIRGGSASTAASNSPGGIINFISKTGEHQG 187
Cdd:PRK13486  96 tlilidgVRQGGSSDVT--PNGFSAMNTG---------FMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNADKW 164
                        170
                 ....*....|
gi 518505941 188 GSiAISSGLN 197
Cdd:PRK13486 165 LS-SVNAGLN 173
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
72-279 3.67e-04

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 43.98  E-value: 3.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  72 LTFEDIDVSSP-RSTAEIFRMLPGVR---SESTGGEGNA-NIAVRGLpvaaGGAKFLTLQeDGLPVLQFGDIAFG-NADI 145
Cdd:PRK13528  56 ITAEDIKKRPPvNDLSDIIRKMPGVNltgNSASGTRGNNrQIDIRGM----GPENTLILI-DGVPVTSRNSVRYSwRGER 130
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 146 FVRADST------MARLDVIRGGSASTAASNSPGGIINFISKT-GEHQGGSIAI-----SSGLNYDQFRTDFEFGGDINN 213
Cdd:PRK13528 131 DTRGDTNwvppemVERIEVIRGPAAARYGSGAAGGVVNIITKRpTNDWHGSLSLytnqpESSKEGATRRANFSLSGPLAG 210
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 214 D---MRFH----------------FGGFVRQG-EGVRDPGYQGERGYQIKANVTKEFSAGYVR---VYAKHLNDRAASYM 270
Cdd:PRK13528 211 DaltMRLYgnlnktdadswdinssAGTKNAAGrEGVRNKDINGVLSWKMTPQQILDFEAGYSRqgnIYAGDTQNSNSSAV 290

                 ....*....
gi 518505941 271 PMPMYADGS 279
Cdd:PRK13528 291 TESLAKSGK 299
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
73-184 7.51e-04

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 43.06  E-value: 7.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  73 TFEDIDVSSPRSTAEIFRMLPGVRSESTGGEG-NANIAVRGLpvaagGAKFLTLQEDGLPVLQFGdIAfGNADIFVRADS 151
Cdd:PRK10641  50 TRDDIDRWQSKSVNDVLRRLPGVDIAQNGGLGqLSSLFIRGT-----NSSHVLVLIDGVRLNQAG-IS-GSADLSQIPIS 122
                         90       100       110
                 ....*....|....*....|....*....|...
gi 518505941 152 TMARLDVIRGGSASTAASNSPGGIINFISKTGE 184
Cdd:PRK10641 123 LVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDK 155
PRK13483 PRK13483
ligand-gated channel protein;
649-807 1.06e-03

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 42.45  E-value: 1.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 649 TTQLFFDRVYkAKGIELESSYRIGD-FDFRGSVTFTDAEISSDALNPDVVGNTPRR--QADMIYSLLARYtmdNAQVGIS 725
Cdd:PRK13483 512 TTYVNIDEAV-TQGVEASLSYPITStLSLSGNYTYTDSEQKSGAYKGSPLNQLPKHlfQASLNWEPTDRL---NSWARVN 587
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 726 LVG-----TTdsyAQDNNDLKFSGYTQLNAFANYELAENLTLSLNVNNLFDTiGITEAEQGSVPEngiitartinGRTAS 800
Cdd:PRK13483 588 YRGeesqpTT---GPSSSSFIAPSYTFLDLGANYQLTDNLKLSAGIYNLFDK-EINYEEYGYVED----------GRRYW 653

                 ....*..
gi 518505941 801 VGLRYQF 807
Cdd:PRK13483 654 LGMTYSF 660
PRK13483 PRK13483
ligand-gated channel protein;
1-244 1.90e-03

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 41.68  E-value: 1.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941   1 MKTRNLnRSCLALAVSLAISSTTAiaqQTDNENDVAAEASASTGLGFERILVTGAVSrnqsvmqssvsVSTLTFEDIDVS 80
Cdd:PRK13483   1 MKKYLA-QVISALCLLPAVFVTHA---LAQAAPDKTMETVVVTASGYEQQIRDAPAS-----------ISVITREDLENR 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941  81 SPRSTAEIFRMLPGVrsESTGGEGNANIAVRGLpvaagGAKFLTLQEDG---------------------LPVLQfgdia 139
Cdd:PRK13483  66 FYRDLTDALLDVPGV--VVTGGGDRTDISLRGM-----GSQYTLILVDGkrqssretrpnsdgpgveqawTPPLA----- 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518505941 140 fgnadifvradsTMARLDVIRGGSASTAASNSPGGIINFIS-KTGEHQGGSIAISSGLNY-----DQFRTDFEFGGDINN 213
Cdd:PRK13483 134 ------------AIERIEVIRGPMSSLYGSDAIGGVINIITrKVPNEWQGEVRLDTTLQEnsdsgNVYQANFFVNGPLIK 201
                        250       260       270
                 ....*....|....*....|....*....|...
gi 518505941 214 DMRFH--FGGFVRQGEGVRDPGYQGERGYQIKA 244
Cdd:PRK13483 202 DLLGLqlYGQYTQREEDDIEGGYRDKDARSLTA 234
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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