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Conserved domains on  [gi|51701917|sp|O94335|]
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RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3; Short=Oligosaccharyl transferase subunit stt3

Protein Classification

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3( domain architecture ID 10494835)

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 is a catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
STT3 pfam02516
Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl ...
23-509 0e+00

Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl transferase STT3 subunit and related proteins. The STT3 subunit is part of the oligosaccharyl transferase (OTase) complex of proteins and is required for its activity. In eukaryotes, OTase transfers a lipid-linked core-oligosaccharide to selected asparagine residues in the ER. In the archaea STT3 occurs alone, rather than in an OTase complex, and is required for N-glycosylation of asparagines.


:

Pssm-ID: 396873  Cd Length: 478  Bit Score: 528.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917    23 PLKVLILICIAVASVSSRLFSVIRYESIIHEFDPWFNFRASKILVEQG-FYNFLNWFDERSWYPLG-RVAGGTLYPGL-M 99
Cdd:pfam02516   1 VLKLVIFAMIAGAAVSSRLFTDERGLSYIHEFDPYYNYRLTENLVNNGhFYGGLNWDDHSTYYPPGsRVDYGPLIPGLtM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   100 VTSGIIFKVLHllrinVNIRDVCVLLAPAFSGITAIATYYLARELKSDACGLLAAAFMGIAPGYTSRSVAGSYDNEAIAI 179
Cdd:pfam02516  81 LTSGIINHSLD-----VSIREVCLWMPPLLGGLTAIPTYFLVREYKDDLAGLLAALLIAIAPGYLSRTVAGFYDTDMFAI 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   180 TLLMSTFALWIKAVKSGS--SFWGACTGLLYFYMVTAWGGYVFITNMIPLHVFVLLLMGRYTSKLYIAYTTYYVIGTLAS 257
Cdd:pfam02516 156 FLPLFVLFFFLKAIKTGSnqIFYAAIAALSIFLMVLAWGGYVFAYNLIPLFIFALLLMGRFELKLYIAYTFSYIIATIVI 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   258 MQVPFVGFQPVSTSEHMSALGVFGLLQLFAFYNYVKGL--VSSKQFQILIRFALVCLVGLATVVLFALSSTGVIAPWTGR 335
Cdd:pfam02516 236 IQILFVGFQPVRSSEHMGALGIFGLLQIHAFGDVVVIVyqLSFYQFISLFQPGLFEVLGLIGPVLFALGVLGLIAPWMGR 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   336 FYSLWDTNYAKIHIPIIASVSEHQPPTWSSLFFDLQFLIWLLPVGVYLCFKELRNEHVFIIIYSVLGTYFCGVMVR-LVL 414
Cdd:pfam02516 316 LYSLWDTEYAKFHIPIIILVSVWLPTGWLALTFGLRFAIFTFPVGLIFTGLLLEFLAVFFIKYSVSQLYFSGVMVRlLML 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   415 TLTPCVCIAAAVAISTLLDTYMGPEVEEDKVSEEAASAKSKNKKGIFSIlsfftsgsknigIYSLLSRVLVISSTAYFLI 494
Cdd:pfam02516 396 TLLPVIAILAAYKASFVFSTYMDEESAIYKAAALSAPFKSLGLYDSLEW------------KGNTNRDSVVITWWDYGHI 463
                         490
                  ....*....|....*
gi 51701917   495 MFVYHSSWVTSNAYS 509
Cdd:pfam02516 464 LAVFADRPVTSDGGS 478
 
Name Accession Description Interval E-value
STT3 pfam02516
Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl ...
23-509 0e+00

Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl transferase STT3 subunit and related proteins. The STT3 subunit is part of the oligosaccharyl transferase (OTase) complex of proteins and is required for its activity. In eukaryotes, OTase transfers a lipid-linked core-oligosaccharide to selected asparagine residues in the ER. In the archaea STT3 occurs alone, rather than in an OTase complex, and is required for N-glycosylation of asparagines.


Pssm-ID: 396873  Cd Length: 478  Bit Score: 528.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917    23 PLKVLILICIAVASVSSRLFSVIRYESIIHEFDPWFNFRASKILVEQG-FYNFLNWFDERSWYPLG-RVAGGTLYPGL-M 99
Cdd:pfam02516   1 VLKLVIFAMIAGAAVSSRLFTDERGLSYIHEFDPYYNYRLTENLVNNGhFYGGLNWDDHSTYYPPGsRVDYGPLIPGLtM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   100 VTSGIIFKVLHllrinVNIRDVCVLLAPAFSGITAIATYYLARELKSDACGLLAAAFMGIAPGYTSRSVAGSYDNEAIAI 179
Cdd:pfam02516  81 LTSGIINHSLD-----VSIREVCLWMPPLLGGLTAIPTYFLVREYKDDLAGLLAALLIAIAPGYLSRTVAGFYDTDMFAI 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   180 TLLMSTFALWIKAVKSGS--SFWGACTGLLYFYMVTAWGGYVFITNMIPLHVFVLLLMGRYTSKLYIAYTTYYVIGTLAS 257
Cdd:pfam02516 156 FLPLFVLFFFLKAIKTGSnqIFYAAIAALSIFLMVLAWGGYVFAYNLIPLFIFALLLMGRFELKLYIAYTFSYIIATIVI 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   258 MQVPFVGFQPVSTSEHMSALGVFGLLQLFAFYNYVKGL--VSSKQFQILIRFALVCLVGLATVVLFALSSTGVIAPWTGR 335
Cdd:pfam02516 236 IQILFVGFQPVRSSEHMGALGIFGLLQIHAFGDVVVIVyqLSFYQFISLFQPGLFEVLGLIGPVLFALGVLGLIAPWMGR 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   336 FYSLWDTNYAKIHIPIIASVSEHQPPTWSSLFFDLQFLIWLLPVGVYLCFKELRNEHVFIIIYSVLGTYFCGVMVR-LVL 414
Cdd:pfam02516 316 LYSLWDTEYAKFHIPIIILVSVWLPTGWLALTFGLRFAIFTFPVGLIFTGLLLEFLAVFFIKYSVSQLYFSGVMVRlLML 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   415 TLTPCVCIAAAVAISTLLDTYMGPEVEEDKVSEEAASAKSKNKKGIFSIlsfftsgsknigIYSLLSRVLVISSTAYFLI 494
Cdd:pfam02516 396 TLLPVIAILAAYKASFVFSTYMDEESAIYKAAALSAPFKSLGLYDSLEW------------KGNTNRDSVVITWWDYGHI 463
                         490
                  ....*....|....*
gi 51701917   495 MFVYHSSWVTSNAYS 509
Cdd:pfam02516 464 LAVFADRPVTSDGGS 478
Stt3 COG1287
Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, ...
26-627 9.11e-63

Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440898 [Multi-domain]  Cd Length: 774  Bit Score: 224.29  E-value: 9.11e-63
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917  26 VLILICIAVASVSSRLFSVIRYES----IIHEFDPWFNFRASKILVEQGFYnfLNWFDERSWYPLGRVAG--GTLYPGLM 99
Cdd:COG1287  17 LPALLLILALALWIRLLPYDNVFRdggvYLGGNDPWYHLRQIEYILANGPS--TLPFDPLTWYPWGRDIGqfGPLFDQLI 94
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 100 VTSGIIFKVLHLLRinVNIRDVCVLLAPAFSGITAIATYYLARELKSDACGLLAAAFMGIAPGYTSRSVAGSYDNEAIAI 179
Cdd:COG1287  95 ALLALILGLGSPSQ--SSVYTVAAWFPPIFGALTVIPVYLLGRRLGGRKAGLLAALLLALSPGQLSRSLLGFADHHVAEL 172
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 180 TLLMSTFALWIKAVKSGSS------------FWGACTGLLYFYMVTAWGGYVFITNMIPLHVFVLLLMGRYTSKlyiaYT 247
Cdd:COG1287 173 FFSTLAVLFLVLALKRAKRekrdlealkrplLYAVLAGVALGLYLLTWGGYVLFVGILALFALLQLLLDLLRGR----SP 248
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 248 TYYVIGTLASMQVPFVGFQPVSTSEHMSALG--------VFGLLQLFAFYNYVKGLVSSKQFQILIRFALVclVGLATVV 319
Cdd:COG1287 249 EYLAIVGAVSFAVAALLVLPFIPRLGFSGTGlsllqpllALALAAGTVFLAWLARELERRDLPRLYYPAAL--VGLVAAG 326
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 320 LFALSSTGviapwtGRFYSLWDTNYAKIHI--PIIASVSEHQPPTWSSLFFDLQFLIWLLPVGVYL----CFKELRNEHV 393
Cdd:COG1287 327 LALLAVLL------PRVLAALIPGLRRFFGasALAATIAEAQPLTLSDLFSSFGIAFFLALIGLLLllyrPLRERRPELL 400
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 394 FIIIYSVLGTYFCGVMVRLVLTLTPCVCIAAAVAISTLLDtymgpeveedkvseeaaSAKSKNKKGifsilsfftSGSKN 473
Cdd:COG1287 401 FLLVWALFSIYAAFTQVRFLYYLAVAVAILAAIGLGELLD-----------------RLDLDKKKR---------EAKKN 454
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 474 IGIYSLLSRVLVIsstayfLIMFVYHSSWVTSNAYSSptvvlstvlnDGSLMYIDDFREAYDWLRRNTP----YDTK--- 546
Cdd:COG1287 455 INGVKILAVALIV------LLLLIPLSASIALSGGSS----------FGPGGINDDWIDALEWLKENTPepgvYPDGayg 518
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 547 VMSWWDYGYQIAGMADRITLVDNNTWNNTHIATVgkAMSSPEEKAYPILRKHD-----VDYILIiyggtlgYSSDDMNKF 621
Cdd:COG1287 519 VLSWWDYGHWITVLGERIPVANPFQQGITGAANF--LLAPSESEAEAILDALHadglgVRYVIV-------DDEMATGKF 589

                ....*.
gi 51701917 622 LWMIRI 627
Cdd:COG1287 590 YAMATW 595
archaeo_STT3 TIGR04154
oligosaccharyl transferase, archaeosortase A system-associated; Members of this protein family ...
53-564 2.60e-37

oligosaccharyl transferase, archaeosortase A system-associated; Members of this protein family occur, one to three members per genome, in the same species of Euryarchaeota as contain the predicted protein-sorting enzyme archaeosortase (TIGR04125) and its cognate protein-sorting signal PGF-CTERM (TIGR04126).


Pssm-ID: 275016 [Multi-domain]  Cd Length: 817  Bit Score: 149.77  E-value: 2.60e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917    53 EFDPWFNFRaskiLVEQGFYNFLN--WFDERSWYPLGRVAG-GTLYPGLMVTSGIIFKVLHLLRinVNIRDVCVLLAPAF 129
Cdd:TIGR04154  32 GNDPWYHLR----RIEYTVHNFPNtlWFDPYTNYPYGTEVGwGPLFDQLGATLALIVGLGAPSR--ETIETVAAFLPPLL 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   130 SGITAIATYYLARELKSDACGLLAAAFMGIAPG-YTSRSVAGSYDNEaIAITLLMSTFAL-WIKAVKSGSS--------- 198
Cdd:TIGR04154 106 GALTVIPVYFIGKRLGDRKTGLLAAFLLAVLPGqFLYRSLFGFVDHH-IAEVLFSTLAVLaFILALAVAREhkpsledld 184
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   199 ------FWGACTGLLYFYMVTAWGGYVFITNMIPLHVFVlllmgRYTSKLYIAYTTYYV-IGTLASMQVPFVGFQPVSTS 271
Cdd:TIGR04154 185 tlkkplLYAVLAGIALGLYLLTWPGAVLFAGIVGVFTLV-----QFILDLFRGRSPEYLaIVGAVTFAVAALLVLPFGFT 259
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   272 EHMSA--------LGVFGLLQLFAFYNYVKGLVSSK---QFQILIRFALVCLVGLATVVLFALSSTGVIAPWTGRFYSlw 340
Cdd:TIGR04154 260 LGFSAtyyslfqpLALLGVALGAVFLAGLSRFWERKdlpRYYYPAAVAGLAALGLAVLALLLPDLFSLIINGLRFFFG-- 337
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   341 DTNYAkihipiiASVSEHQP-----PTWS--SLFFDLQFLIWLLPVG----VYLCFKELRNEHVFIIIYSVLGTYFCGVM 409
Cdd:TIGR04154 338 RTGTA-------LTIAEAQPlfstgGGFSlaPAWSNFGLGFLLAIAGlallLYRLLRKYRPEELFLLVWSLFILYATLTQ 410
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   410 VRLVLTLTPCVCIAAAVAISTLLDtymgpeveedKVSEEAASAKSKNKKGIFSILSfftsgsknigiysllSRVLVISST 489
Cdd:TIGR04154 411 VRFEYYLAVNVAVLSAYLLGWVLD----------FAGRLPLRRSLKNKKDIETYQV---------------SRIAVILLL 465
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   490 AYFLIMFVyhsswvtsnayssPTVVLSTVLNDGSLMYIDDFREAYDWLRRNTP---------YDTK-----------VMS 549
Cdd:TIGR04154 466 IVILVLAY-------------PSIWATAAQSTGPGGPNQDWVDALEWLKNNTPdtgldyygiYEEKddfpypegsygVMS 532
                         570
                  ....*....|....*
gi 51701917   550 WWDYGYQIAGMADRI 564
Cdd:TIGR04154 533 WWDYGHWITYIGERI 547
 
Name Accession Description Interval E-value
STT3 pfam02516
Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl ...
23-509 0e+00

Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl transferase STT3 subunit and related proteins. The STT3 subunit is part of the oligosaccharyl transferase (OTase) complex of proteins and is required for its activity. In eukaryotes, OTase transfers a lipid-linked core-oligosaccharide to selected asparagine residues in the ER. In the archaea STT3 occurs alone, rather than in an OTase complex, and is required for N-glycosylation of asparagines.


Pssm-ID: 396873  Cd Length: 478  Bit Score: 528.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917    23 PLKVLILICIAVASVSSRLFSVIRYESIIHEFDPWFNFRASKILVEQG-FYNFLNWFDERSWYPLG-RVAGGTLYPGL-M 99
Cdd:pfam02516   1 VLKLVIFAMIAGAAVSSRLFTDERGLSYIHEFDPYYNYRLTENLVNNGhFYGGLNWDDHSTYYPPGsRVDYGPLIPGLtM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   100 VTSGIIFKVLHllrinVNIRDVCVLLAPAFSGITAIATYYLARELKSDACGLLAAAFMGIAPGYTSRSVAGSYDNEAIAI 179
Cdd:pfam02516  81 LTSGIINHSLD-----VSIREVCLWMPPLLGGLTAIPTYFLVREYKDDLAGLLAALLIAIAPGYLSRTVAGFYDTDMFAI 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   180 TLLMSTFALWIKAVKSGS--SFWGACTGLLYFYMVTAWGGYVFITNMIPLHVFVLLLMGRYTSKLYIAYTTYYVIGTLAS 257
Cdd:pfam02516 156 FLPLFVLFFFLKAIKTGSnqIFYAAIAALSIFLMVLAWGGYVFAYNLIPLFIFALLLMGRFELKLYIAYTFSYIIATIVI 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   258 MQVPFVGFQPVSTSEHMSALGVFGLLQLFAFYNYVKGL--VSSKQFQILIRFALVCLVGLATVVLFALSSTGVIAPWTGR 335
Cdd:pfam02516 236 IQILFVGFQPVRSSEHMGALGIFGLLQIHAFGDVVVIVyqLSFYQFISLFQPGLFEVLGLIGPVLFALGVLGLIAPWMGR 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   336 FYSLWDTNYAKIHIPIIASVSEHQPPTWSSLFFDLQFLIWLLPVGVYLCFKELRNEHVFIIIYSVLGTYFCGVMVR-LVL 414
Cdd:pfam02516 316 LYSLWDTEYAKFHIPIIILVSVWLPTGWLALTFGLRFAIFTFPVGLIFTGLLLEFLAVFFIKYSVSQLYFSGVMVRlLML 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   415 TLTPCVCIAAAVAISTLLDTYMGPEVEEDKVSEEAASAKSKNKKGIFSIlsfftsgsknigIYSLLSRVLVISSTAYFLI 494
Cdd:pfam02516 396 TLLPVIAILAAYKASFVFSTYMDEESAIYKAAALSAPFKSLGLYDSLEW------------KGNTNRDSVVITWWDYGHI 463
                         490
                  ....*....|....*
gi 51701917   495 MFVYHSSWVTSNAYS 509
Cdd:pfam02516 464 LAVFADRPVTSDGGS 478
Stt3 COG1287
Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, ...
26-627 9.11e-63

Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440898 [Multi-domain]  Cd Length: 774  Bit Score: 224.29  E-value: 9.11e-63
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917  26 VLILICIAVASVSSRLFSVIRYES----IIHEFDPWFNFRASKILVEQGFYnfLNWFDERSWYPLGRVAG--GTLYPGLM 99
Cdd:COG1287  17 LPALLLILALALWIRLLPYDNVFRdggvYLGGNDPWYHLRQIEYILANGPS--TLPFDPLTWYPWGRDIGqfGPLFDQLI 94
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 100 VTSGIIFKVLHLLRinVNIRDVCVLLAPAFSGITAIATYYLARELKSDACGLLAAAFMGIAPGYTSRSVAGSYDNEAIAI 179
Cdd:COG1287  95 ALLALILGLGSPSQ--SSVYTVAAWFPPIFGALTVIPVYLLGRRLGGRKAGLLAALLLALSPGQLSRSLLGFADHHVAEL 172
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 180 TLLMSTFALWIKAVKSGSS------------FWGACTGLLYFYMVTAWGGYVFITNMIPLHVFVLLLMGRYTSKlyiaYT 247
Cdd:COG1287 173 FFSTLAVLFLVLALKRAKRekrdlealkrplLYAVLAGVALGLYLLTWGGYVLFVGILALFALLQLLLDLLRGR----SP 248
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 248 TYYVIGTLASMQVPFVGFQPVSTSEHMSALG--------VFGLLQLFAFYNYVKGLVSSKQFQILIRFALVclVGLATVV 319
Cdd:COG1287 249 EYLAIVGAVSFAVAALLVLPFIPRLGFSGTGlsllqpllALALAAGTVFLAWLARELERRDLPRLYYPAAL--VGLVAAG 326
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 320 LFALSSTGviapwtGRFYSLWDTNYAKIHI--PIIASVSEHQPPTWSSLFFDLQFLIWLLPVGVYL----CFKELRNEHV 393
Cdd:COG1287 327 LALLAVLL------PRVLAALIPGLRRFFGasALAATIAEAQPLTLSDLFSSFGIAFFLALIGLLLllyrPLRERRPELL 400
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 394 FIIIYSVLGTYFCGVMVRLVLTLTPCVCIAAAVAISTLLDtymgpeveedkvseeaaSAKSKNKKGifsilsfftSGSKN 473
Cdd:COG1287 401 FLLVWALFSIYAAFTQVRFLYYLAVAVAILAAIGLGELLD-----------------RLDLDKKKR---------EAKKN 454
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 474 IGIYSLLSRVLVIsstayfLIMFVYHSSWVTSNAYSSptvvlstvlnDGSLMYIDDFREAYDWLRRNTP----YDTK--- 546
Cdd:COG1287 455 INGVKILAVALIV------LLLLIPLSASIALSGGSS----------FGPGGINDDWIDALEWLKENTPepgvYPDGayg 518
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917 547 VMSWWDYGYQIAGMADRITLVDNNTWNNTHIATVgkAMSSPEEKAYPILRKHD-----VDYILIiyggtlgYSSDDMNKF 621
Cdd:COG1287 519 VLSWWDYGHWITVLGERIPVANPFQQGITGAANF--LLAPSESEAEAILDALHadglgVRYVIV-------DDEMATGKF 589

                ....*.
gi 51701917 622 LWMIRI 627
Cdd:COG1287 590 YAMATW 595
archaeo_STT3 TIGR04154
oligosaccharyl transferase, archaeosortase A system-associated; Members of this protein family ...
53-564 2.60e-37

oligosaccharyl transferase, archaeosortase A system-associated; Members of this protein family occur, one to three members per genome, in the same species of Euryarchaeota as contain the predicted protein-sorting enzyme archaeosortase (TIGR04125) and its cognate protein-sorting signal PGF-CTERM (TIGR04126).


Pssm-ID: 275016 [Multi-domain]  Cd Length: 817  Bit Score: 149.77  E-value: 2.60e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917    53 EFDPWFNFRaskiLVEQGFYNFLN--WFDERSWYPLGRVAG-GTLYPGLMVTSGIIFKVLHLLRinVNIRDVCVLLAPAF 129
Cdd:TIGR04154  32 GNDPWYHLR----RIEYTVHNFPNtlWFDPYTNYPYGTEVGwGPLFDQLGATLALIVGLGAPSR--ETIETVAAFLPPLL 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   130 SGITAIATYYLARELKSDACGLLAAAFMGIAPG-YTSRSVAGSYDNEaIAITLLMSTFAL-WIKAVKSGSS--------- 198
Cdd:TIGR04154 106 GALTVIPVYFIGKRLGDRKTGLLAAFLLAVLPGqFLYRSLFGFVDHH-IAEVLFSTLAVLaFILALAVAREhkpsledld 184
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   199 ------FWGACTGLLYFYMVTAWGGYVFITNMIPLHVFVlllmgRYTSKLYIAYTTYYV-IGTLASMQVPFVGFQPVSTS 271
Cdd:TIGR04154 185 tlkkplLYAVLAGIALGLYLLTWPGAVLFAGIVGVFTLV-----QFILDLFRGRSPEYLaIVGAVTFAVAALLVLPFGFT 259
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   272 EHMSA--------LGVFGLLQLFAFYNYVKGLVSSK---QFQILIRFALVCLVGLATVVLFALSSTGVIAPWTGRFYSlw 340
Cdd:TIGR04154 260 LGFSAtyyslfqpLALLGVALGAVFLAGLSRFWERKdlpRYYYPAAVAGLAALGLAVLALLLPDLFSLIINGLRFFFG-- 337
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   341 DTNYAkihipiiASVSEHQP-----PTWS--SLFFDLQFLIWLLPVG----VYLCFKELRNEHVFIIIYSVLGTYFCGVM 409
Cdd:TIGR04154 338 RTGTA-------LTIAEAQPlfstgGGFSlaPAWSNFGLGFLLAIAGlallLYRLLRKYRPEELFLLVWSLFILYATLTQ 410
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   410 VRLVLTLTPCVCIAAAVAISTLLDtymgpeveedKVSEEAASAKSKNKKGIFSILSfftsgsknigiysllSRVLVISST 489
Cdd:TIGR04154 411 VRFEYYLAVNVAVLSAYLLGWVLD----------FAGRLPLRRSLKNKKDIETYQV---------------SRIAVILLL 465
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51701917   490 AYFLIMFVyhsswvtsnayssPTVVLSTVLNDGSLMYIDDFREAYDWLRRNTP---------YDTK-----------VMS 549
Cdd:TIGR04154 466 IVILVLAY-------------PSIWATAAQSTGPGGPNQDWVDALEWLKNNTPdtgldyygiYEEKddfpypegsygVMS 532
                         570
                  ....*....|....*
gi 51701917   550 WWDYGYQIAGMADRI 564
Cdd:TIGR04154 533 WWDYGHWITYIGERI 547
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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