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Conserved domains on  [gi|516299291|ref|WP_017702598|]
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methyl-accepting chemotaxis protein [Pseudomonas syringae]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
14-541 2.84e-94

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 297.32  E-value: 2.84e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  14 LGFTLISLLVALLGWFALAQMSTIRQSEVAVETNWLPSMRVVNDIREIMLRIRTISLRMALDTDPASIPTYRGQLDVRLG 93
Cdd:COG0840    6 LLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  94 DLNKKLDTLKTFVDTPEEKTLNDQFLVTMGQYRTALDRSFVLAGQGDSAGLNKLLLIDMKQIVDGSGKQLNDLADFYVTK 173
Cdd:COG0840   86 LALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 174 VDAEGKSAEAQYDKSRNIVIVFVVIAALCTIGLALWLTRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALA 253
Cdd:COG0840  166 LLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFN 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 254 LMQGNLRDAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAVSTSDASSQSSNSA 333
Cdd:COG0840  246 RMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELA 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 334 QAGQTRVIETVQSIEILTENVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEV 413
Cdd:COG0840  326 EEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEV 405

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 414 RALAHRTQQSTLEIDSMVNAMRSGSAQALESMNTSRERASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQAQV 493
Cdd:COG0840  406 RKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSAG 485

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 516299291 494 SREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVLRFKV 541
Cdd:COG0840  486 TEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
14-541 2.84e-94

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 297.32  E-value: 2.84e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  14 LGFTLISLLVALLGWFALAQMSTIRQSEVAVETNWLPSMRVVNDIREIMLRIRTISLRMALDTDPASIPTYRGQLDVRLG 93
Cdd:COG0840    6 LLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  94 DLNKKLDTLKTFVDTPEEKTLNDQFLVTMGQYRTALDRSFVLAGQGDSAGLNKLLLIDMKQIVDGSGKQLNDLADFYVTK 173
Cdd:COG0840   86 LALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 174 VDAEGKSAEAQYDKSRNIVIVFVVIAALCTIGLALWLTRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALA 253
Cdd:COG0840  166 LLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFN 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 254 LMQGNLRDAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAVSTSDASSQSSNSA 333
Cdd:COG0840  246 RMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELA 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 334 QAGQTRVIETVQSIEILTENVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEV 413
Cdd:COG0840  326 EEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEV 405

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 414 RALAHRTQQSTLEIDSMVNAMRSGSAQALESMNTSRERASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQAQV 493
Cdd:COG0840  406 RKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSAG 485

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 516299291 494 SREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVLRFKV 541
Cdd:COG0840  486 TEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 279-540 1.54e-63

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 208.29  E-value: 1.54e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291   279 ELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAVSTSDASSQSSNSAQAGQTRVIETVQSIEILTENVQATS 358
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291   359 TLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRALAHRTQQSTLEIDSMVNAMRSGS 438
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEET 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291   439 AQALESMNTSRERASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQAQVSREVDRNIVNIRDLSMQSTQGANQI 518
Cdd:smart00283 161 NEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|..
gi 516299291   519 SASSHELSRLAADLNQVVLRFK 540
Cdd:smart00283 241 SAAAEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 306-505 2.00e-50

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 171.65  E-value: 2.00e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 306 NEMTSAVEEVARNAVSTSDASSQSSNSAQAGQTRVIETVQSIEILTENVQATSTLVQNLANQSQDIGKVLDVIRSIAEQT 385
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 386 NLLALNAAIEAARAGESGRGFAVVADEVRALAHRTQQSTLEIDSMVNAMRSGSAQALESMNTSRERASSTLSLAKGAGES 465
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 516299291 466 LSEITSSINQISERNLVIASAAEEQAQVSREVDRNIVNIR 505
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
174-541 1.71e-42

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 159.47  E-value: 1.71e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 174 VDAEGKSAEAQYDKSRNIVIVFVVIAALCTIGLALWLTRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALA 253
Cdd:PRK09793 174 LEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPLAIIGSHFDSIAAGNLARPIAVYGRNEITAIFASLK 253

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 254 LMQGNLRDAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAVSTSDASSQSSNSA 333
Cdd:PRK09793 254 TMQQALRGTVSDVRKGSQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTA 333

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 334 QAGqtrvietvqsieilTENVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEV 413
Cdd:PRK09793 334 QAG--------------GVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV 399

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 414 RALAHRTQQSTLEIDSMVNamrsgsaqalESMNtsreRASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQAQV 493
Cdd:PRK09793 400 RNLASRSAQAAKEIKGLIE----------ESVN----RVQQGSKLVNNAAATMTDIVSSVTRVNDIMGEIASASEEQRRG 465

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 516299291 494 SREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVLRFKV 541
Cdd:PRK09793 466 IEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVAVFTL 513
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 364-508 7.11e-36

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 131.79  E-value: 7.11e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  364 LANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRALAHRTQQSTLEIDSMVNAMRSGSAQALE 443
Cdd:pfam00015  28 IAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEIEALIIEIQKQTNDSTA 107

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 516299291  444 SMNTSRERASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQAQVSREVDRNIVNIRDLS 508
Cdd:pfam00015 108 SIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVARMDQVT 172
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
14-541 2.84e-94

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 297.32  E-value: 2.84e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  14 LGFTLISLLVALLGWFALAQMSTIRQSEVAVETNWLPSMRVVNDIREIMLRIRTISLRMALDTDPASIPTYRGQLDVRLG 93
Cdd:COG0840    6 LLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  94 DLNKKLDTLKTFVDTPEEKTLNDQFLVTMGQYRTALDRSFVLAGQGDSAGLNKLLLIDMKQIVDGSGKQLNDLADFYVTK 173
Cdd:COG0840   86 LALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 174 VDAEGKSAEAQYDKSRNIVIVFVVIAALCTIGLALWLTRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALA 253
Cdd:COG0840  166 LLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFN 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 254 LMQGNLRDAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAVSTSDASSQSSNSA 333
Cdd:COG0840  246 RMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELA 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 334 QAGQTRVIETVQSIEILTENVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEV 413
Cdd:COG0840  326 EEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEV 405

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 414 RALAHRTQQSTLEIDSMVNAMRSGSAQALESMNTSRERASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQAQV 493
Cdd:COG0840  406 RKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSAG 485

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 516299291 494 SREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVLRFKV 541
Cdd:COG0840  486 TEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 279-540 1.54e-63

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 208.29  E-value: 1.54e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291   279 ELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAVSTSDASSQSSNSAQAGQTRVIETVQSIEILTENVQATS 358
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291   359 TLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRALAHRTQQSTLEIDSMVNAMRSGS 438
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEET 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291   439 AQALESMNTSRERASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQAQVSREVDRNIVNIRDLSMQSTQGANQI 518
Cdd:smart00283 161 NEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|..
gi 516299291   519 SASSHELSRLAADLNQVVLRFK 540
Cdd:smart00283 241 SAAAEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 306-505 2.00e-50

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 171.65  E-value: 2.00e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 306 NEMTSAVEEVARNAVSTSDASSQSSNSAQAGQTRVIETVQSIEILTENVQATSTLVQNLANQSQDIGKVLDVIRSIAEQT 385
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 386 NLLALNAAIEAARAGESGRGFAVVADEVRALAHRTQQSTLEIDSMVNAMRSGSAQALESMNTSRERASSTLSLAKGAGES 465
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 516299291 466 LSEITSSINQISERNLVIASAAEEQAQVSREVDRNIVNIR 505
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
174-541 1.71e-42

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 159.47  E-value: 1.71e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 174 VDAEGKSAEAQYDKSRNIVIVFVVIAALCTIGLALWLTRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALA 253
Cdd:PRK09793 174 LEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPLAIIGSHFDSIAAGNLARPIAVYGRNEITAIFASLK 253

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 254 LMQGNLRDAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAVSTSDASSQSSNSA 333
Cdd:PRK09793 254 TMQQALRGTVSDVRKGSQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTA 333

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 334 QAGqtrvietvqsieilTENVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEV 413
Cdd:PRK09793 334 QAG--------------GVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV 399

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 414 RALAHRTQQSTLEIDSMVNamrsgsaqalESMNtsreRASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQAQV 493
Cdd:PRK09793 400 RNLASRSAQAAKEIKGLIE----------ESVN----RVQQGSKLVNNAAATMTDIVSSVTRVNDIMGEIASASEEQRRG 465

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 516299291 494 SREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVLRFKV 541
Cdd:PRK09793 466 IEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVAVFTL 513
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
192-541 2.28e-41

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 156.65  E-value: 2.28e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 192 VIVFVVIAALCTIgLALWL--TRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALALMQGNLRDAMRHIGSS 269
Cdd:PRK15041 195 ILVGVMIVVLAVI-FAVWFgiKASLVAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNG 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 270 ATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAVSTSDASSQSSNSAQAGQTRVIETVQSIei 349
Cdd:PRK15041 274 ANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTM-- 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 350 ltenvqatstlvQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRALAHRTQQSTLEIDS 429
Cdd:PRK15041 352 ------------RDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKS 419

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 430 MVNAmrsgsaqalesmNTSRERASSTlsLAKGAGESLSEITSSINQISERNLVIASAAEEQAQVSREVDRNIVNIRDLSM 509
Cdd:PRK15041 420 LIED------------SVGKVDVGST--LVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQ 485

                        330       340       350
                 ....*....|....*....|....*....|..
gi 516299291 510 QSTQGANQISASSHELSRLAADLNQVVLRFKV 541
Cdd:PRK15041 486 QNAALVEESAAAAAALEEQASRLTEAVAVFRI 517
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 364-508 7.11e-36

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 131.79  E-value: 7.11e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  364 LANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRALAHRTQQSTLEIDSMVNAMRSGSAQALE 443
Cdd:pfam00015  28 IAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEIEALIIEIQKQTNDSTA 107

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 516299291  444 SMNTSRERASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQAQVSREVDRNIVNIRDLS 508
Cdd:pfam00015 108 SIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVARMDQVT 172
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 196-541 1.95e-34

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 136.67  E-value: 1.95e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 196 VVIAALCTIGLALW--LTRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALALMQGNLRDAMRHI--GSSA- 270
Cdd:PRK15048 196 VIALVVVLILLVAWygIRRMLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVreGSDAi 275

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 271 ----TQLASAATELNSVTEdsyrglnQQNAEIDQAATAINEMTSAVEEVARNAVSTSDASSQSSNSAQAGQTRVIETVQS 346
Cdd:PRK15048 276 yagtREIAAGNTDLSSRTE-------QQASALEETAASMEQLTATVKQNADNARQASQLAQSASDTAQHGGKVVDGVVKT 348

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 347 IeiltenvqatstlvQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRALAHRTQQSTLE 426
Cdd:PRK15048 349 M--------------HEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKE 414

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 427 IDSMVnamrsgsaqalesmNTSRERASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQaqvSREVDRNIVNIRD 506
Cdd:PRK15048 415 IKALI--------------EDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIMGEIASASDEQ---SRGIDQVALAVSE 477

                        330       340       350
                 ....*....|....*....|....*....|....*...
gi 516299291 507 LSMQSTQGANQI---SASSHELSRLAADLNQVVLRFKV 541
Cdd:PRK15048 478 MDRVTQQNASLVqesAAAAAALEEQASRLTQAVSAFRL 515
4HB_MCP_1 pfam12729
Four helix bundle sensory module for signal transduction; This family is a four helix bundle ...
 5-185 2.41e-10

Four helix bundle sensory module for signal transduction; This family is a four helix bundle that operates as a ubiquitous sensory module in prokaryotic signal-transduction. The 4HB_MCP is always found between two predicted transmembrane helices indicating that it detects only extracellular signals. In many cases the domain is associated with a cytoplasmic HAMP domain suggesting that most proteins carrying the bundle might share the mechanism of transmembrane signalling which is well-characterized in E coli chemoreceptors. This domain recognizes citrate and TCA cycle intermediates, cis-aconitate, boric acid, Phenanthrene, pyrene and benzopyrene (Matilla et el., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 432749 [Multi-domain]  Cd Length: 181  Bit Score: 59.57  E-value: 2.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291    5 KLTIARRAGLGFTLISLLVALLGWFALAQMSTIRQSEVAVETNWLPSMRVVNDIREIMLRIRTISLRMALDTDPAsiptY 84
Cdd:pfam12729   1 NLKIRTKLILLFLLLALLLIIVGVVGLYSLKQINDNLDTMYEDRLLPIKWLGDIRANLLELRANLLELILTTDPA----E 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291   85 RGQLDVRLGDLNKKLDTL----KTFVDTPEEKTLNDQFLVTMGQYRTALDRSFVLAGQGDSAGLNKLLLIDMKQIVDGSG 160
Cdd:pfam12729  77 RDELLKDIEELRAEIDKLlekyEKTILTDEEKKLFAEFKENLNAYRAVRNKVLELAKAGNKDEAYQLYKTEGRPAREAMI 156

                         170       180
                  ....*....|....*....|....*
gi 516299291  161 KQLNDLADFYVTKVDAEGKSAEAQY 185
Cdd:pfam12729 157 EALEELVDYNLKVAKEAYKDNKASY 181
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 191-266 3.35e-10

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 62.29  E-value: 3.35e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516299291 191 IVIVFVVIAALCTIGLALWLTRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALALMQGNLRDAMRHI 266
Cdd:COG5000   10 LLLLIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQREEL 85
HAMP pfam00672
HAMP domain;
209-261 1.69e-09

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 53.40  E-value: 1.69e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 516299291  209 WLTRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALALMQGNLRD 261
Cdd:pfam00672   1 LLARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
HAMP smart00304
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
212-264 6.31e-09

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;


Pssm-ID: 197640 [Multi-domain]  Cd Length: 53  Bit Score: 51.87  E-value: 6.31e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 516299291   212 RSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALALMQGNLRDAMR 264
Cdd:smart00304   1 RRLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
MCP2201-like_sensor cd19411
ligand-binding sensor domain of Comamonas testosteroni CNB-2 MCP2201 and similar ...
 46-181 1.06e-08

ligand-binding sensor domain of Comamonas testosteroni CNB-2 MCP2201 and similar chemoreceptors; This family includes the ligand-binding sensor domain of Comamonas testosteroni transmembrane chemoreceptor CNB-2 MCP2201 and similar chemoreceptors. The C. testosteroni methyl-accepting chemotaxis protein MCP2201 triggers chemotaxis towards tricarboxylic acid cycle intermediates such as citric acid and aromatic compounds. While the apo-form ligand binding domain (LBD) forms a typical four-helix bundle homodimer, similar to other chemoreceptors in the superfamily such as Escherichia coli Tar and Tsr, the citrate-bound LBD reveals a four-helix bundle homotrimer. This type of oligomerization has never been observed in other bacterial chemoreceptor LBD. Site-directed mutations of key amino acid residues have demonstrated the physiological importance of the homotrimer for chemotaxis.


Pssm-ID: 438629 [Multi-domain]  Cd Length: 138  Bit Score: 53.80  E-value: 1.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  46 TNWLPSMRVVNDIREIMLRIRTISLRMALDTDPASIPTYRGQLDVRLGDLNKKLDTLKTFVDTPEEKTLNDQFLVTMGQY 125
Cdd:cd19411    3 EDRYPKVRLANEWKDNVNANARRTRNLLLSTDPAERAKELARIAAARARITELLKKLEKLITSPEGKALLAAIAEARAAY 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 516299291 126 RTALDRSFVLAGQGDSAGLNKLLLIDMKQIVDGSGKQLNDLADFYVTKVDAEGKSA 181
Cdd:cd19411   83 LAARDKVLELKKAGDREEARALLLGELRPAQAAYLAALDALVDYQEELMDAAAAEA 138
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
1-538 5.71e-08

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 55.50  E-value: 5.71e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291   1 MNLRKLTIARRAGLGFTLISLLVALLGWFALAQMSTIRQSEVAVETNWLPSMRVVNDIREIMLRIRTISLRMALDTDPAS 80
Cdd:COG2770   29 ALISLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAA 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  81 IPTYRGQLDVRLGDLNKKLDTLKTFVDTPEEKTLNDQFLVTMGQYRTALDRSFVLAGQGDSAGLNKLLLIDMKQIVDGSG 160
Cdd:COG2770  109 LLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLA 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 161 KQLNDLADFYVTKVDAEGKSAEAQydksrnIVIVFVVIAALCTIGLALWLTRSIVSPLQRAVTAAEQVAAGDLTHSIEVD 240
Cdd:COG2770  189 ALLLLLLGGLLLVVLLEAALAALL------LLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVS 262

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 241 GEDEVTRLLRALALMQGNLRDAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAV 320
Cdd:COG2770  263 RKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLL 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 321 STSDASSQSSNSAQAGQTRVIETVQSIEILTENVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAG 400
Cdd:COG2770  343 LLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALL 422

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 401 ESGRGFAVVADEVRALAHRTQQSTLEIDSMVNAMRSGSAQALESMNTSRERASSTLSLAKGAGESLSEITSSINQISERN 480
Cdd:COG2770  423 ALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAA 502

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 516299291 481 LVIASAAEEQAQVSREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVLR 538
Cdd:COG2770  503 EELAEELLLLEGLLLLLLLEAEALEVAEELLELEEAALLLAAAAELAALLALLLALAA 560
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 215-259 4.94e-07

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 46.28  E-value: 4.94e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 516299291 215 VSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALALMQGNL 259
Cdd:cd06225    1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
COG4192 COG4192
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ...
 72-264 7.36e-07

Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];


Pssm-ID: 443346 [Multi-domain]  Cd Length: 640  Bit Score: 52.00  E-value: 7.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  72 MALDTDPASIPTYRGQLDVRLGDLNKKLDTLKTFVDTPEEKTLNDQfLVTMGQYRTAL------DRSFVLAGQGDSAGLN 145
Cdd:COG4192  211 VAAARDQADVDNLFDRLQYLKDELDRNLQALKNYPSTITLRQLIDE-LLAIGSGEGGLpslrrdELAAQATLEALAEENN 289

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 146 KLLlidmKQIvdgsGKQLNDLADFYVTKVDAEGKSAEAQYDKSRNIVIVFVVIAALCTIGLA-LWLTRSIVSPLQRAVTA 224
Cdd:COG4192  290 SIL----EQL----RTQISGLVGNSREQLVALNQETAQLVQQSGILLLAIALLSLLLAVLINyFYVRRRLVKRLNALSDA 361

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 516299291 225 AEQVAAGDLTHSIEVDGEDEVTRLLRALALMQGNLRDAMR 264
Cdd:COG4192  362 MAAIAAGDLDVPIPVDGNDEIGRIARLLRVFRDQAIEKTQ 401
NarQ COG3850
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ...
 189-505 1.08e-05

Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];


Pssm-ID: 443059 [Multi-domain]  Cd Length: 448  Bit Score: 47.96  E-value: 1.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 189 RNIVIVFVVIAALCTIGLALWLTRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALALMQGNLRDAMRHIGS 268
Cdd:COG3850  117 RKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELYAELEE 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 269 SATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAVSTSDASSQSSNSAQAGQTRVIETVQSIE 348
Cdd:COG3850  197 EEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLAS 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 349 ILTENVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRALAHRTQQSTLEID 428
Cdd:COG3850  277 ALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAALEAA 356

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 516299291 429 SMVNAMRSGSAQALESMNTSRERASSTLSLAKGAGESLSEITSSINQISERNLVIASAAEEQAQVSREVDRNIVNIR 505
Cdd:COG3850  357 AAGAALAAAAAAAGLARALAQAGADAAEALGLLAEASEGAAGQGAGLVDVEGGVAGEGGLVVLIVSIIAGGEAIARG 433
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
3-531 2.38e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 40.66  E-value: 2.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291   3 LRKLTIARRAGLGFTLISLLVALLGWFALAQMSTIRQSEVAVETNwLPSMRVVNDIREIMLRIRTISLRMALDTDPASIP 82
Cdd:COG5278    1 MKNLSIRRKLLLGFALALLLLLVLGVLSYLSLNRLREASEWVEHT-YEVLRALEELLSALLDAETGQRGYLLTGDESFLE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291  83 TYRGQLDvrlgDLNKKLDTLKTFV-DTPEEKTLNDQFLVTMGQYRTALDRSFVLAGQGDSAGLNKLLLID-----MKQIV 156
Cdd:COG5278   80 PYEEARA----EIDELLAELRSLTaDNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGegkalMDEIR 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 157 DGSGKQLNDLADFYVTKVDAEGKSAEAQYDKSRNIVIVFVVIAALCTIGLALWLTRSIVSPLQRAVTAAEQVAAGDLTHS 236
Cdd:COG5278  156 ARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELL 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 237 IEVDGEDEVTRLLRALALMQGNLRDAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVA 316
Cdd:COG5278  236 AALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAA 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 317 RNAVSTSDASSQSSNSAQAGQTRVIETVQSIEILTENVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEA 396
Cdd:COG5278  316 AAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAI 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516299291 397 ARAGESGRGFAVVADEVRALAHRTQQSTLEIDSMVNAMRSGSAQALESMNTSRERASSTLSLAKGAGESLSEITSSINQI 476
Cdd:COG5278  396 AAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALA 475

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 516299291 477 SERNLVIASAAEEQAQVSREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAAD 531
Cdd:COG5278  476 ALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASAEL 530
PRK10549 PRK10549
two-component system sensor histidine kinase BaeS;
197-248 5.04e-03

two-component system sensor histidine kinase BaeS;


Pssm-ID: 182539 [Multi-domain]  Cd Length: 466  Bit Score: 39.62  E-value: 5.04e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 516299291 197 VIAALCTI--GLALWLT-RSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRL 248
Cdd:PRK10549 168 LIVALSTLlaALATFLLaRGLLAPVKRLVEGTHKLAAGDFTTRVTPTSRDELGRL 222
PRK10600 PRK10600
nitrate/nitrite two-component system sensor histidine kinase NarX;
194-260 7.23e-03

nitrate/nitrite two-component system sensor histidine kinase NarX;


Pssm-ID: 182581 [Multi-domain]  Cd Length: 569  Bit Score: 39.27  E-value: 7.23e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 516299291 194 VFVVIAALCTIGLALWLTRSIVSPLQRAVTAAEQVAAGDLTHSIEVDGEDEVTRLLRALALMQGNLR 260
Cdd:PRK10600 129 VFAVFMALLLVFTIIWLRRRLLQPWRQLLSMANAVSHRDFTQRANISGRDEMAMLGTALNNMSAELA 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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