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Conserved domains on  [gi|515955875|ref|WP_017386458|]
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MULTISPECIES: plasmid replication DNA-binding protein [Acinetobacter]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
rep_pAB02_ORF2 super family cl45742
plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal ...
 2-132 5.77e-30

plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal DNA-binding helix-turn-helix domain, occurs in replication regions of a large number of Acinetobacter plasmids. The founding members of this family, AAR00518.1 and WP_000839337.1 from plasmids pAB02 and pMAC, are referred to as ORF2 there, sitting adjacent to RepM, which in turn is adjacent to the DNA repeat region at each plasmid's origin of replication.


The actual alignment was detected with superfamily member NF038291:

Pssm-ID: 468456  Cd Length: 172  Bit Score: 105.87  E-value: 5.77e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955875   2 ARITVTQASKDFNISRNTLYKKIKQGHLTKDSNGLLDVNDLIRVIGahtESTSKNVTLNTSDIQSVSSDTQLQQAKSEVE 81
Cdd:NF038291   1 AKLSVSEASKLFNISRSTIYKAIKKGDLSKDSDGLIDLSEAIRVFG---EPSKKSTDVNTSQSINSQKSTEVELLKQQVD 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955875  82 QLKQLLAQKEIFINQLQQQIADLRQ-----------------------------------DKEQLYNQINQKRL---EH- 122
Cdd:NF038291  78 MLKKQLEQAKERESFYQKQIDDLQLlleykapkpnmttftdqpeandtatdpqpeteqkhDGLTTPEETENKRIpvpEHv 157

                        170
                 ....*....|....*
gi 515955875 123 -----KKGLLGRFFG 132
Cdd:NF038291 158 epepkKRGLFGRFFG 172
 
Name Accession Description Interval E-value
rep_pAB02_ORF2 NF038291
plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal ...
 2-132 5.77e-30

plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal DNA-binding helix-turn-helix domain, occurs in replication regions of a large number of Acinetobacter plasmids. The founding members of this family, AAR00518.1 and WP_000839337.1 from plasmids pAB02 and pMAC, are referred to as ORF2 there, sitting adjacent to RepM, which in turn is adjacent to the DNA repeat region at each plasmid's origin of replication.


Pssm-ID: 468456  Cd Length: 172  Bit Score: 105.87  E-value: 5.77e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955875   2 ARITVTQASKDFNISRNTLYKKIKQGHLTKDSNGLLDVNDLIRVIGahtESTSKNVTLNTSDIQSVSSDTQLQQAKSEVE 81
Cdd:NF038291   1 AKLSVSEASKLFNISRSTIYKAIKKGDLSKDSDGLIDLSEAIRVFG---EPSKKSTDVNTSQSINSQKSTEVELLKQQVD 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955875  82 QLKQLLAQKEIFINQLQQQIADLRQ-----------------------------------DKEQLYNQINQKRL---EH- 122
Cdd:NF038291  78 MLKKQLEQAKERESFYQKQIDDLQLlleykapkpnmttftdqpeandtatdpqpeteqkhDGLTTPEETENKRIpvpEHv 157

                        170
                 ....*....|....*
gi 515955875 123 -----KKGLLGRFFG 132
Cdd:NF038291 158 epepkKRGLFGRFFG 172
AcoR COG3284
Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];
6-26 2.99e-03

Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];


Pssm-ID: 442514 [Multi-domain]  Cd Length: 625  Bit Score: 36.42  E-value: 2.99e-03
                         10        20
                 ....*....|....*....|.
gi 515955875   6 VTQASKDFNISRNTLYKKIKQ 26
Cdd:COG3284  603 VSAAARALGISRSTLYRKLKR 623
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 43-124 8.17e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 35.09  E-value: 8.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955875    43 IRVIGAHTESTSKNVTLNTSDIQSVSSD-TQLQQAKSEVEQLKQLLAQKEIFINQLQQQIADLRQ--------------D 107
Cdd:pfam15921  512 IEATNAEITKLRSRVDLKLQELQHLKNEgDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrtagamqvE 591

                           90
                   ....*....|....*..
gi 515955875   108 KEQLYNQINQKRLEHKK 124
Cdd:pfam15921  592 KAQLEKEINDRRLELQE 608
 
Name Accession Description Interval E-value
rep_pAB02_ORF2 NF038291
plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal ...
 2-132 5.77e-30

plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal DNA-binding helix-turn-helix domain, occurs in replication regions of a large number of Acinetobacter plasmids. The founding members of this family, AAR00518.1 and WP_000839337.1 from plasmids pAB02 and pMAC, are referred to as ORF2 there, sitting adjacent to RepM, which in turn is adjacent to the DNA repeat region at each plasmid's origin of replication.


Pssm-ID: 468456  Cd Length: 172  Bit Score: 105.87  E-value: 5.77e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955875   2 ARITVTQASKDFNISRNTLYKKIKQGHLTKDSNGLLDVNDLIRVIGahtESTSKNVTLNTSDIQSVSSDTQLQQAKSEVE 81
Cdd:NF038291   1 AKLSVSEASKLFNISRSTIYKAIKKGDLSKDSDGLIDLSEAIRVFG---EPSKKSTDVNTSQSINSQKSTEVELLKQQVD 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955875  82 QLKQLLAQKEIFINQLQQQIADLRQ-----------------------------------DKEQLYNQINQKRL---EH- 122
Cdd:NF038291  78 MLKKQLEQAKERESFYQKQIDDLQLlleykapkpnmttftdqpeandtatdpqpeteqkhDGLTTPEETENKRIpvpEHv 157

                        170
                 ....*....|....*
gi 515955875 123 -----KKGLLGRFFG 132
Cdd:NF038291 158 epepkKRGLFGRFFG 172
AcoR COG3284
Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];
6-26 2.99e-03

Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];


Pssm-ID: 442514 [Multi-domain]  Cd Length: 625  Bit Score: 36.42  E-value: 2.99e-03
                         10        20
                 ....*....|....*....|.
gi 515955875   6 VTQASKDFNISRNTLYKKIKQ 26
Cdd:COG3284  603 VSAAARALGISRSTLYRKLKR 623
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 43-124 8.17e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 35.09  E-value: 8.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955875    43 IRVIGAHTESTSKNVTLNTSDIQSVSSD-TQLQQAKSEVEQLKQLLAQKEIFINQLQQQIADLRQ--------------D 107
Cdd:pfam15921  512 IEATNAEITKLRSRVDLKLQELQHLKNEgDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrtagamqvE 591

                           90
                   ....*....|....*..
gi 515955875   108 KEQLYNQINQKRLEHKK 124
Cdd:pfam15921  592 KAQLEKEINDRRLELQE 608
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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