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Conserved domains on  [gi|515201464|ref|WP_016809293|]
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MULTISPECIES: 4-hydroxybenzoate 3-monooxygenase [Klebsiella]

Protein Classification

4-hydroxybenzoate 3-monooxygenase( domain architecture ID 10013028)

4-hydroxybenzoate 3-monooxygenase catalyzes the formation of protocatechuate from 4-hydroxybenzoate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK08243 PRK08243
4-hydroxybenzoate 3-monooxygenase; Validated
 1-392 0e+00

4-hydroxybenzoate 3-monooxygenase; Validated


:

Pssm-ID: 236198 [Multi-domain]  Cd Length: 392  Bit Score: 718.50  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGRIRAGILESGTVELLREAGAARRMEAEGLVHHGVEFLFE 80
Cdd:PRK08243   1 MRTQVAIIGAGPAGLLLGQLLHLAGIDSVVLERRSREYVEGRIRAGVLEQGTVDLLREAGVGERMDREGLVHDGIELRFD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  81 GKRVPVALTELTAGKSVMVYGQTEVTRDLMAARAECGAATIYGVSEVTINEAKSDRPSVSFISNGEHCRLECDFIAGCDG 160
Cdd:PRK08243  81 GRRHRIDLTELTGGRAVTVYGQTEVTRDLMAARLAAGGPIRFEASDVALHDFDSDRPYVTYEKDGEEHRLDCDFIAGCDG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 161 FHGVSRQSIPPGVLKEYESVWPFGWLGLLADTPPVNPELIYAHHERGFVLCSQRSLTRSRYYLQVPLSEKVEAWSDERFW 240
Cdd:PRK08243 161 FHGVSRASIPAGALRTFERVYPFGWLGILAEAPPVSDELIYANHERGFALCSMRSPTRSRYYLQCPLDDKVEDWSDERFW 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 241 NELKRRLPEELSSKLVTGHSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYLWRILREYYHHG 320
Cdd:PRK08243 241 DELRRRLPPEDAERLVTGPSIEKSIAPLRSFVAEPMQYGRLFLAGDAAHIVPPTGAKGLNLAASDVRYLARALVEFYREG 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515201464 321 RVDLLASYSRFALDRVWKGERFSWFMTRLLHDFPQQSEFDRKMQAADRRYYLGSRAGLTTIAENYVGLPMER 392
Cdd:PRK08243 321 DTALLDAYSATALRRVWKAERFSWWMTSMLHRFPDDDPFDQRIQLAELDYLTSSRAAATTLAENYVGLPFED 392
 
Name Accession Description Interval E-value
PRK08243 PRK08243
4-hydroxybenzoate 3-monooxygenase; Validated
 1-392 0e+00

4-hydroxybenzoate 3-monooxygenase; Validated


Pssm-ID: 236198 [Multi-domain]  Cd Length: 392  Bit Score: 718.50  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGRIRAGILESGTVELLREAGAARRMEAEGLVHHGVEFLFE 80
Cdd:PRK08243   1 MRTQVAIIGAGPAGLLLGQLLHLAGIDSVVLERRSREYVEGRIRAGVLEQGTVDLLREAGVGERMDREGLVHDGIELRFD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  81 GKRVPVALTELTAGKSVMVYGQTEVTRDLMAARAECGAATIYGVSEVTINEAKSDRPSVSFISNGEHCRLECDFIAGCDG 160
Cdd:PRK08243  81 GRRHRIDLTELTGGRAVTVYGQTEVTRDLMAARLAAGGPIRFEASDVALHDFDSDRPYVTYEKDGEEHRLDCDFIAGCDG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 161 FHGVSRQSIPPGVLKEYESVWPFGWLGLLADTPPVNPELIYAHHERGFVLCSQRSLTRSRYYLQVPLSEKVEAWSDERFW 240
Cdd:PRK08243 161 FHGVSRASIPAGALRTFERVYPFGWLGILAEAPPVSDELIYANHERGFALCSMRSPTRSRYYLQCPLDDKVEDWSDERFW 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 241 NELKRRLPEELSSKLVTGHSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYLWRILREYYHHG 320
Cdd:PRK08243 241 DELRRRLPPEDAERLVTGPSIEKSIAPLRSFVAEPMQYGRLFLAGDAAHIVPPTGAKGLNLAASDVRYLARALVEFYREG 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515201464 321 RVDLLASYSRFALDRVWKGERFSWFMTRLLHDFPQQSEFDRKMQAADRRYYLGSRAGLTTIAENYVGLPMER 392
Cdd:PRK08243 321 DTALLDAYSATALRRVWKAERFSWWMTSMLHRFPDDDPFDQRIQLAELDYLTSSRAAATTLAENYVGLPFED 392
pbenz_hydroxyl TIGR02360
4-hydroxybenzoate 3-monooxygenase; Members of this family are the enzyme 4-hydroxybenzoate ...
 1-389 0e+00

4-hydroxybenzoate 3-monooxygenase; Members of this family are the enzyme 4-hydroxybenzoate 3-monooxygenase, also called p-hydroxybenzoate hydroxylase. It converts 4-hydroxybenzoate + NADPH + molecular oxygen to protocatechuate + NADPH + water. It contains monooxygenase (pfam01360) and FAD binding (pfam01494) domains. Pathways that contain this enzyme include the protocatechuate 4,5-degradation pathway. [Energy metabolism, Other]


Pssm-ID: 131413 [Multi-domain]  Cd Length: 390  Bit Score: 619.85  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464    1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGRIRAGILESGTVELLREAGAARRMEAEGLVHHGVEFLFE 80
Cdd:TIGR02360   1 MKTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQSRDYVLGRIRAGVLEQGTVDLLREAGVDERMDREGLVHEGTEIAFD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   81 GKRVPVALTELTAGKSVMVYGQTEVTRDLMAARAECGAATIYGVSEVTINEAKSDRPSVSFISNGEHCRLECDFIAGCDG 160
Cdd:TIGR02360  81 GQRFRIDLKALTGGKTVMVYGQTEVTRDLMEAREAAGLTTVYDADDVRLHDLAGDRPYVTFERDGERHRLDCDFIAGCDG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  161 FHGVSRQSIPPGVLKEYESVWPFGWLGLLADTPPVNPELIYAHHERGFVLCSQRSLTRSRYYLQVPLSEKVEAWSDERFW 240
Cdd:TIGR02360 161 FHGVSRASIPAEVLKEFERVYPFGWLGILSETPPVSHELIYSNHERGFALCSMRSATRSRYYVQVPLTDKVEDWSDDRFW 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  241 NELKRRLPEELSSKLVTGHSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYLWRILREYYHHG 320
Cdd:TIGR02360 241 AELKRRLPSEAAERLVTGPSIEKSIAPLRSFVCEPMQYGRLFLAGDAAHIVPPTGAKGLNLAASDVHYLYEALLEHYQEG 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515201464  321 RVDLLASYSRFALDRVWKGERFSWFMTRLLHDFPQQSEFDRKMQAADRRYYLGSRAGLTTIAENYVGLP 389
Cdd:TIGR02360 321 SSAGIEGYSARALARVWKAERFSWWMTSLLHRFPDTDAFDQRIQQAELEYLLGSEAAQATLAENYVGLP 389
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 2-343 3.19e-99

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 298.86  E-value: 3.19e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464    2 KTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGRirAGILESGTVELLREAGAARRMEAEGLVHHGVEFLFEG 81
Cdd:pfam01494   1 ETDVLIVGGGPAGLMLALLLARAGVRVVLVERHATTSVLPR--AHGLNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYN 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   82 KRVPVALTELTAGKSVMVYGQTEVTRDLMAARAECGAaTIYGVSEVTINEAKSD--RPSVSFISNGEHCRLECDFIAGCD 159
Cdd:pfam01494  79 TRRRADLDFLTSPPRVTVYPQTELEPILVEHAEARGA-QVRFGTEVLSLEQDGDgvTAVVRDRRDGEEYTVRAKYLVGCD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  160 GFHGVSRQSIppGVLKEYESVWPFGWLGLLADTPPVNP--------ELIYAHHERGFVLCSQRSLTRSRYYLQVPLSEKV 231
Cdd:pfam01494 158 GGRSPVRKTL--GIEFEGFEGVPFGSLDVLFDAPDLSDpverafvhYLIYAPHSRGFMVGPWRSAGRERYYVQVPWDEEV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  232 EAWSDERFWNELKRRLPEELSSKLVTGHSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYL-W 310
Cdd:pfam01494 236 EERPEEFTDEELKQRLRSIVGIDLALVEILWKSIWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLaW 315

                         330       340       350
                  ....*....|....*....|....*....|...
gi 515201464  311 RILREYYHHGRVDLLASYSRFALDRVWKGERFS 343
Cdd:pfam01494 316 KLAAVLRGQAGESLLDTYSAERLPVAWAVVDFA 348
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-351 1.13e-38

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 141.23  E-value: 1.13e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGriRAGILESGTVELLREAGAARRMEAEGLVHHGVEFLFE 80
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDG--RGIALSPRSLELLRRLGLWDRLLARGAPIRGIRVRDG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  81 GKRVPVALTELTAGKSVMVYG--QTEVTRDLMAARAECGAATIYGVSEVTInEAKSDRPSVSFiSNGEhcRLECDFIAGC 158
Cdd:COG0654   80 SDGRVLARFDAAETGLPAGLVvpRADLERALLEAARALGVELRFGTEVTGL-EQDADGVTVTL-ADGR--TLRADLVVGA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 159 DGFHGVSRQSIPPGVLkEYESVWPFGWLGLLADtppvnpeliyahhergfvlcsqrsltrsryylqvpLSEKVEAWSDer 238
Cdd:COG0654  156 DGARSAVRRLLGIGFT-GRDYPQRALWAGVRTE-----------------------------------LRARLAAAGP-- 197

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 239 fwnelkrRLPEELssklvtgHSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYLWRILREYYH 318
Cdd:COG0654  198 -------RLGELL-------ELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAALR 263

                        330       340       350
                 ....*....|....*....|....*....|....
gi 515201464 319 HGRVD-LLASYSRFALDRVWKGERFSWFMTRLLH 351
Cdd:COG0654  264 GRDDEaALARYERERRPRAARVQRAADALGRLFH 297
 
Name Accession Description Interval E-value
PRK08243 PRK08243
4-hydroxybenzoate 3-monooxygenase; Validated
 1-392 0e+00

4-hydroxybenzoate 3-monooxygenase; Validated


Pssm-ID: 236198 [Multi-domain]  Cd Length: 392  Bit Score: 718.50  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGRIRAGILESGTVELLREAGAARRMEAEGLVHHGVEFLFE 80
Cdd:PRK08243   1 MRTQVAIIGAGPAGLLLGQLLHLAGIDSVVLERRSREYVEGRIRAGVLEQGTVDLLREAGVGERMDREGLVHDGIELRFD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  81 GKRVPVALTELTAGKSVMVYGQTEVTRDLMAARAECGAATIYGVSEVTINEAKSDRPSVSFISNGEHCRLECDFIAGCDG 160
Cdd:PRK08243  81 GRRHRIDLTELTGGRAVTVYGQTEVTRDLMAARLAAGGPIRFEASDVALHDFDSDRPYVTYEKDGEEHRLDCDFIAGCDG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 161 FHGVSRQSIPPGVLKEYESVWPFGWLGLLADTPPVNPELIYAHHERGFVLCSQRSLTRSRYYLQVPLSEKVEAWSDERFW 240
Cdd:PRK08243 161 FHGVSRASIPAGALRTFERVYPFGWLGILAEAPPVSDELIYANHERGFALCSMRSPTRSRYYLQCPLDDKVEDWSDERFW 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 241 NELKRRLPEELSSKLVTGHSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYLWRILREYYHHG 320
Cdd:PRK08243 241 DELRRRLPPEDAERLVTGPSIEKSIAPLRSFVAEPMQYGRLFLAGDAAHIVPPTGAKGLNLAASDVRYLARALVEFYREG 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515201464 321 RVDLLASYSRFALDRVWKGERFSWFMTRLLHDFPQQSEFDRKMQAADRRYYLGSRAGLTTIAENYVGLPMER 392
Cdd:PRK08243 321 DTALLDAYSATALRRVWKAERFSWWMTSMLHRFPDDDPFDQRIQLAELDYLTSSRAAATTLAENYVGLPFED 392
pbenz_hydroxyl TIGR02360
4-hydroxybenzoate 3-monooxygenase; Members of this family are the enzyme 4-hydroxybenzoate ...
 1-389 0e+00

4-hydroxybenzoate 3-monooxygenase; Members of this family are the enzyme 4-hydroxybenzoate 3-monooxygenase, also called p-hydroxybenzoate hydroxylase. It converts 4-hydroxybenzoate + NADPH + molecular oxygen to protocatechuate + NADPH + water. It contains monooxygenase (pfam01360) and FAD binding (pfam01494) domains. Pathways that contain this enzyme include the protocatechuate 4,5-degradation pathway. [Energy metabolism, Other]


Pssm-ID: 131413 [Multi-domain]  Cd Length: 390  Bit Score: 619.85  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464    1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGRIRAGILESGTVELLREAGAARRMEAEGLVHHGVEFLFE 80
Cdd:TIGR02360   1 MKTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQSRDYVLGRIRAGVLEQGTVDLLREAGVDERMDREGLVHEGTEIAFD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   81 GKRVPVALTELTAGKSVMVYGQTEVTRDLMAARAECGAATIYGVSEVTINEAKSDRPSVSFISNGEHCRLECDFIAGCDG 160
Cdd:TIGR02360  81 GQRFRIDLKALTGGKTVMVYGQTEVTRDLMEAREAAGLTTVYDADDVRLHDLAGDRPYVTFERDGERHRLDCDFIAGCDG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  161 FHGVSRQSIPPGVLKEYESVWPFGWLGLLADTPPVNPELIYAHHERGFVLCSQRSLTRSRYYLQVPLSEKVEAWSDERFW 240
Cdd:TIGR02360 161 FHGVSRASIPAEVLKEFERVYPFGWLGILSETPPVSHELIYSNHERGFALCSMRSATRSRYYVQVPLTDKVEDWSDDRFW 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  241 NELKRRLPEELSSKLVTGHSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYLWRILREYYHHG 320
Cdd:TIGR02360 241 AELKRRLPSEAAERLVTGPSIEKSIAPLRSFVCEPMQYGRLFLAGDAAHIVPPTGAKGLNLAASDVHYLYEALLEHYQEG 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515201464  321 RVDLLASYSRFALDRVWKGERFSWFMTRLLHDFPQQSEFDRKMQAADRRYYLGSRAGLTTIAENYVGLP 389
Cdd:TIGR02360 321 SSAGIEGYSARALARVWKAERFSWWMTSLLHRFPDTDAFDQRIQQAELEYLLGSEAAQATLAENYVGLP 389
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 2-343 3.19e-99

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 298.86  E-value: 3.19e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464    2 KTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGRirAGILESGTVELLREAGAARRMEAEGLVHHGVEFLFEG 81
Cdd:pfam01494   1 ETDVLIVGGGPAGLMLALLLARAGVRVVLVERHATTSVLPR--AHGLNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYN 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   82 KRVPVALTELTAGKSVMVYGQTEVTRDLMAARAECGAaTIYGVSEVTINEAKSD--RPSVSFISNGEHCRLECDFIAGCD 159
Cdd:pfam01494  79 TRRRADLDFLTSPPRVTVYPQTELEPILVEHAEARGA-QVRFGTEVLSLEQDGDgvTAVVRDRRDGEEYTVRAKYLVGCD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  160 GFHGVSRQSIppGVLKEYESVWPFGWLGLLADTPPVNP--------ELIYAHHERGFVLCSQRSLTRSRYYLQVPLSEKV 231
Cdd:pfam01494 158 GGRSPVRKTL--GIEFEGFEGVPFGSLDVLFDAPDLSDpverafvhYLIYAPHSRGFMVGPWRSAGRERYYVQVPWDEEV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  232 EAWSDERFWNELKRRLPEELSSKLVTGHSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYL-W 310
Cdd:pfam01494 236 EERPEEFTDEELKQRLRSIVGIDLALVEILWKSIWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLaW 315

                         330       340       350
                  ....*....|....*....|....*....|...
gi 515201464  311 RILREYYHHGRVDLLASYSRFALDRVWKGERFS 343
Cdd:pfam01494 316 KLAAVLRGQAGESLLDTYSAERLPVAWAVVDFA 348
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-351 1.13e-38

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 141.23  E-value: 1.13e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGriRAGILESGTVELLREAGAARRMEAEGLVHHGVEFLFE 80
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDG--RGIALSPRSLELLRRLGLWDRLLARGAPIRGIRVRDG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  81 GKRVPVALTELTAGKSVMVYG--QTEVTRDLMAARAECGAATIYGVSEVTInEAKSDRPSVSFiSNGEhcRLECDFIAGC 158
Cdd:COG0654   80 SDGRVLARFDAAETGLPAGLVvpRADLERALLEAARALGVELRFGTEVTGL-EQDADGVTVTL-ADGR--TLRADLVVGA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 159 DGFHGVSRQSIPPGVLkEYESVWPFGWLGLLADtppvnpeliyahhergfvlcsqrsltrsryylqvpLSEKVEAWSDer 238
Cdd:COG0654  156 DGARSAVRRLLGIGFT-GRDYPQRALWAGVRTE-----------------------------------LRARLAAAGP-- 197

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 239 fwnelkrRLPEELssklvtgHSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYLWRILREYYH 318
Cdd:COG0654  198 -------RLGELL-------ELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAALR 263

                        330       340       350
                 ....*....|....*....|....*....|....
gi 515201464 319 HGRVD-LLASYSRFALDRVWKGERFSWFMTRLLH 351
Cdd:COG0654  264 GRDDEaALARYERERRPRAARVQRAADALGRLFH 297
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 5-330 1.42e-10

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 62.22  E-value: 1.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464    5 VAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVL-----GRIRAgiLESGTVELLREAGA---ARRMEAEGLvhHGVE 76
Cdd:TIGR01988   2 IVIVGGGMVGLALALALARSGLKVALIEATPLPAPAdpgfdNRVSA--LSAASIRLLEKLGVwdkIEPARAQPI--RDIH 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   77 FLFEGKRVPVALTELTAGKSVMvyGQTEVTRDLMAAR----AECGAATIYGVSEVTINEAKSDRPSVSFiSNGEhcRLEC 152
Cdd:TIGR01988  78 VSDGGSFGALRFDADEIGLEAL--GYVVENRVLQQALwerlQELPNVTLLCPARVVELPRHSDHVELTL-DDGQ--QLRA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  153 DFIAGCDGFHGVSRQS--IPPgvlkeyeSVWPFGWLGLLAdtppvNPELIYAHHERGFvlcsQRSLT------------R 218
Cdd:TIGR01988 153 RLLVGADGANSKVRQLagIPT-------TGWDYGQSAVVA-----NVKHERPHQGTAW----ERFTPtgplallplpdnR 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  219 SR--YYLQVPLSEKVEAWSDERFWNELKRRLPEELSsKLVTghSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGA 296
Cdd:TIGR01988 217 SSlvWTLPPEEAERLLALSDEEFLAELQRAFGSRLG-AITL--VGERHAFPLSLTHAKRYVAPRLALIGDAAHTIHPLAG 293

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 515201464  297 KGLNLAASDVNYLWRILREYYHHGR----VDLLASYSR 330
Cdd:TIGR01988 294 QGLNLGLRDVAALAEVLEDARRRGEdigsLRVLQRYER 331
PRK06126 PRK06126
hypothetical protein; Provisional
 1-328 1.94e-10

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 62.32  E-value: 1.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQ--TPEYVlgriRAGILESGTVELLREAGAARRMEAEGL-------- 70
Cdd:PRK06126   6 SETPVLIVGGGPVGLALALDLGRRGVDSILVERKdgTAFNP----KANTTSARSMEHFRRLGIADEVRSAGLpvdyptdi 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  71 ----VHHGVE---FLFEGKRVPVALTELTAGKSVMVY-----GQTEVTRDLMAARAECGAATIYGVSEVTINEAKSDRPS 138
Cdd:PRK06126  82 ayftRLTGYElarFRLPSAREAITPVGGPDGSWPSPElphriPQKYLEPILLEHAAAQPGVTLRYGHRLTDFEQDADGVT 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 139 VSF--ISNGEHCRLECDFIAGCDGFHGVSRQSIppGVLKEYESVwpfgwlgllaDTPPVN-----PELIYAH-HERG--- 207
Cdd:PRK06126 162 ATVedLDGGESLTIRADYLVGCDGARSAVRRSL--GISYEGTSG----------LQRDLSiyiraPGLAALVgHDPAwmy 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 208 FVLCSQRSLT------RSRYYLQVPLSEKVEAWSDERFWNELKRRL-----PEELSSKLV-TGHSLeksiaplrsyVVEP 275
Cdd:PRK06126 230 WLFNPDRRGVlvaidgRDEWLFHQLRGGEDEFTIDDVDARAFVRRGvgediDYEVLSVVPwTGRRL----------VADS 299

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 515201464 276 MQYGRLFLVGDAAHIVPPTGAKGLNLAASD-VNYLWRILREYYHHGRVDLLASY 328
Cdd:PRK06126 300 YRRGRVFLAGDAAHLFTPTGGYGMNTGIGDaVNLAWKLAAVLNGWAGPALLDSY 353
PRK07190 PRK07190
FAD-binding protein;
1-328 4.20e-09

FAD-binding protein;


Pssm-ID: 235955 [Multi-domain]  Cd Length: 487  Bit Score: 57.90  E-value: 4.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKTQVA---IIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGRirAGILESGTVELLREAGAARRMEAEGLVHHGVEF 77
Cdd:PRK07190   1 MSTQVTdvvIIGAGPVGLMCAYLGQLCGLNTVIVDKSDGPLEVGR--ADALNARTLQLLELVDLFDELYPLGKPCNTSSV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  78 LFEGKRVPVALT-----ELTAGKSVMVYGQTEVTRDLMAARAECGAATIYgvSEVTINEAKSDRPSVSFISNGEhcRLEC 152
Cdd:PRK07190  79 WANGKFISRQSSwweelEGCLHKHFLMLGQSYVEKLLDDKLKEAGAAVKR--NTSVVNIELNQAGCLTTLSNGE--RIQS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 153 DFIAGCDGFHGVSRQ--SIPPGVLKEyESVWPFGWLGLLADTPPVnPELIYAHHERGFVLCSQRSLTRSRYYLQVPLSEk 230
Cdd:PRK07190 155 RYVIGADGSRSFVRNhfNVPFEIIRP-QIIWAVIDGVIDTDFPKV-PEIIVFQAETSDVAWIPREGEIDRFYVRMDTKD- 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 231 veaWSDERFWNELKRRL-PEELSSKLV---TGHSLEKSIAplRSYVVEpmqyGRLFLVGDAAHIVPPTGAKGLNLAASDV 306
Cdd:PRK07190 232 ---FTLEQAIAKINHAMqPHRLGFKEIvwfSQFSVKESVA--EHFFIQ----DRIFLAGDACHIHSVNGGQGLNTGLADA 302

                        330       340
                 ....*....|....*....|...
gi 515201464 307 -NYLWRILREYYHHGRVDLLASY 328
Cdd:PRK07190 303 fNLIWKLNMVIHHGASPELLQSY 325
PRK06847 PRK06847
hypothetical protein; Provisional
 4-305 1.78e-08

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 55.65  E-value: 1.78e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   4 QVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGrirAGILESG-TVELLREAGAARRMEAEGLVHHGVE-FLFEG 81
Cdd:PRK06847   6 KVLIVGGGIGGLSAAIALRRAGIAVDLVEIDPEWRVYG---AGITLQGnALRALRELGVLDECLEAGFGFDGVDlFDPDG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  82 KRVPVALTELTAGKSV---MVYGQTEVTRDLMAARAECGAATIYGVSeVTINEAKSDRPSVSFiSNGEHCRLecDFIAGC 158
Cdd:PRK06847  83 TLLAELPTPRLAGDDLpggGGIMRPALARILADAARAAGADVRLGTT-VTAIEQDDDGVTVTF-SDGTTGRY--DLVVGA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 159 DGFHGVSRQSIPPGVLK-EY--ESVW------------PFGWLG--LLADTPPVNPELIYAhhergFVLcsqrSLTRSRY 221
Cdd:PRK06847 159 DGLYSKVRSLVFPDEPEpEYtgQGVWravlprpaevdrSLMYLGptTKAGVVPLSEDLMYL-----FVT----EPRPDNP 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 222 YLQvplsekveawsDERFWNELKRRLpEELSSKLVTghSLEKSIA--------PLRSYVV-EPMQYGRLFLVGDAAHIVP 292
Cdd:PRK06847 230 RIE-----------PDTLAALLRELL-APFGGPVLQ--ELREQITddaqvvyrPLETLLVpAPWHRGRVVLIGDAAHATT 295

                        330
                 ....*....|...
gi 515201464 293 PTGAKGLNLAASD 305
Cdd:PRK06847 296 PHLAQGAGMAIED 308
PRK06834 PRK06834
hypothetical protein; Provisional
 1-312 4.10e-07

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 51.94  E-value: 4.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGRiRAGILESGTVELLREAGAARRmeaeglvhhgveFLFE 80
Cdd:PRK06834   2 TEHAVVIAGGGPTGLMLAGELALAGVDVAIVERRPNQELVGS-RAGGLHARTLEVLDQRGIADR------------FLAQ 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  81 GKRVPV---ALTELTAGK--SVMVYG----QTEVTRDLMAARAECGaATIYGVSEVTiNEAKSDRPSVSFISNGEhcRLE 151
Cdd:PRK06834  69 GQVAQVtgfAATRLDISDfpTRHNYGlalwQNHIERILAEWVGELG-VPIYRGREVT-GFAQDDTGVDVELSDGR--TLR 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 152 CDFIAGCDGFHGVSRQSIP---PGvlkeyesvWPFGWLGLLADTP-PVNPELIYAHHERGFvlcsqRSLTRSRY--YLQV 225
Cdd:PRK06834 145 AQYLVGCDGGRSLVRKAAGidfPG--------WDPTTSYLIAEVEmTEEPEWGVHRDALGI-----HAFGRLEDegPVRV 211

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 226 PLSEKVEAWSDErfwnelkrRLPEELSSKLVTG-------HSLeKSIAPLRSYVVEPMQY--GRLFLVGDAAHIVPPTGA 296
Cdd:PRK06834 212 MVTEKQVGATGE--------PTLDDLREALIAVygtdygiHSP-TWISRFTDMARQAASYrdGRVLLAGDAAHVHSPVGG 282

                        330
                 ....*....|....*..
gi 515201464 297 KGLNLAASD-VNYLWRI 312
Cdd:PRK06834 283 QGLNTGVQDaVNLGWKL 299
PRK08244 PRK08244
monooxygenase;
1-372 4.21e-07

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 51.67  E-value: 4.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILER--QTPEYVlgriRAGILESGTVELLREAGAARRMEAEG-LVHHGvef 77
Cdd:PRK08244   1 MKYEVIIIGGGPVGLMLASELALAGVKTCVIERlkETVPYS----KALTLHPRTLEILDMRGLLERFLEKGrKLPSG--- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  78 LFEGKRVPVALTEL-TAGKSVMVYGQTEVTRDLMAARAECGAATIYGVSEVTINEaksDRPSVSFISNGEHCR--LECDF 154
Cdd:PRK08244  74 HFAGLDTRLDFSALdTSSNYTLFLPQAETEKVLEEHARSLGVEIFRGAEVLAVRQ---DGDGVEVVVRGPDGLrtLTSSY 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 155 IAGCDGFHGVSRQS--IP-PGVLKEYESVwpfgwLG--LLADTPPVNpeLIYAHHERGFVLCS------QRSLTRSRYYL 223
Cdd:PRK08244 151 VVGADGAGSIVRKQagIAfPGTDATFTAM-----LGdvVLKDPPPSS--VLSLCTREGGVMIVplsggiYRVLIIDPERP 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 224 QVPLSEKVeawSDERFWNELKRRLPEELssklvtGHSLEKSIAPLRSYVVEPMQY--GRLFLVGDAAHIVPPTGAKGLNL 301
Cdd:PRK08244 224 QVPKDEPV---TLEELKTSLIRICGTDF------GLNDPVWMSRFGNATRQAERYrsGRIFLAGDAAHIHFPAGGQGLNV 294

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 302 AASD-VNYLWRILREYYHHGRVDLLASYsrfaldrvwKGERFSWF--------MTRLLHDFPQQSEFDRKM-----QAAD 367
Cdd:PRK08244 295 GLQDaMNLGWKLAAAIKGWAPDWLLDSY---------HAERHPVGtallrnteVQTKLFDFTRPGLALRSMlsdllGFPE 365


                 ....*
gi 515201464 368 RRYYL 372
Cdd:PRK08244 366 VNRYL 370
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
279-330 4.86e-06

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 48.36  E-value: 4.86e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 515201464 279 GRLFLVGDAAHIVPPTGAKGLNLAASDVNYLWRILREYYHH-GRVDLLASYSR 330
Cdd:PRK07494 280 GRTALVGEAAHVFPPIGAQGLNLGLRDVATLVEIVEDRPEDpGSAAVLAAYDR 332
PRK06184 PRK06184
hypothetical protein; Provisional
 279-328 9.94e-06

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 47.29  E-value: 9.94e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 515201464 279 GRLFLVGDAAHIVPPTGAKGLNLAASDV-NYLWRiLREYYHHGRVDLLASY 328
Cdd:PRK06184 281 GRVFLAGDAAHVHPPAGGQGLNTSVQDAyNLGWK-LAAVLAGAPEALLDTY 330
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
1-328 2.65e-05

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 46.05  E-value: 2.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKTQVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYvlGRIRAGILESGTVELLREAGAARRMEAEGLVHHGVEFLFE 80
Cdd:PRK06183   9 HDTDVVIVGAGPVGLTLANLLGQYGVRVLVLERWPTLY--DLPRAVGIDDEALRVLQAIGLADEVLPHTTPNHGMRFLDA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  81 GKRVpvaLTELtAGKSVMVYG--------QTEVTRDLMAARAECGAATIYGVSEVTINEAKSDRPSVSFIS-NGEHCRLE 151
Cdd:PRK06183  87 KGRC---LAEI-ARPSTGEFGwprrnafhQPLLEAVLRAGLARFPHVRVRFGHEVTALTQDDDGVTVTLTDaDGQRETVR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 152 CDFIAGCDGFHGVSRQSIppGVLKE---YESVWpfgwlgLLADTPPVNPELIYAHHErgfVLCS-QRSLT-------RSR 220
Cdd:PRK06183 163 ARYVVGCDGANSFVRRTL--GVPFEdltFPERW------LVVDVLIANDPLGGPHTY---QYCDpARPYTsvrlphgRRR 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 221 YYLQVPLSEKVEAW-SDERFWNELKRRLPE----ELSSKLVTGHsleksiaplRSYVVEPMQYGRLFLVGDAAHIVPPTG 295
Cdd:PRK06183 232 WEFMLLPGETEEQLaSPENVWRLLAPWGPTpddaELIRHAVYTF---------HARVADRWRSGRVLLAGDAAHLMPPFA 302

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 515201464 296 AKGLNLAASDV-NYLWRILReyYHHGRVD--LLASY 328
Cdd:PRK06183 303 GQGMNSGIRDAaNLAWKLAA--VLRGRAGdaLLDTY 336
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
228-335 4.91e-05

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 45.24  E-value: 4.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 228 SEKVEAWSDERFWNELKRRLPEELSSKLVTGhslEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVN 307
Cdd:PRK08773 234 AERVLALDEAAFSRELTQAFAARLGEVRVAS---PRTAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVA 310

                         90       100       110
                 ....*....|....*....|....*....|
gi 515201464 308 YLWRILREyYHHGRVDLLASY--SRFALDR 335
Cdd:PRK08773 311 ALQQLVRQ-AHARRADWAAPHrlQRWARTR 339
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 5-305 9.40e-05

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 44.38  E-value: 9.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   5 VAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGR---IRAGILESGTVELLREAGA-----ARR------ME---- 66
Cdd:PRK08850   7 VAIIGGGMVGLALAAALKESDLRIAVIEGQLPEEALNElpdVRVSALSRSSEHILRNLGAwqgieARRaapyiaMEvweq 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  67 ---------AEGLVHHGVEFLFEGKRVPVALTEltagksvMVYGQTEVTRdLMAARAecgAATIYGVSEVTINeaksdrp 137
Cdd:PRK08850  87 dsfariefdAESMAQPDLGHIVENRVIQLALLE-------QVQKQDNVTL-LMPARC---QSIAVGESEAWLT------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 138 svsfISNGEhcRLECDFIAGCDGFHG-VSRQ-SIPPgvlkeyeSVWPFGWLGLLADTPPVNP------ELIYAHHERGFV 209
Cdd:PRK08850 149 ----LDNGQ--ALTAKLVVGADGANSwLRRQmDIPL-------THWDYGHSALVANVRTVDPhnsvarQIFTPQGPLAFL 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 210 LCSQRSLTRSRYYLQVPLSEKVEAWSDERFwnelKRRLPEELSSKL----VTGhslEKSIAPL-----RSYVVEpmqygR 280
Cdd:PRK08850 216 PMSEPNMSSIVWSTEPLRAEALLAMSDEQF----NKALTAEFDNRLglceVVG---ERQAFPLkmryaRDFVRE-----R 283

                        330       340
                 ....*....|....*....|....*
gi 515201464 281 LFLVGDAAHIVPPTGAKGLNLAASD 305
Cdd:PRK08850 284 VALVGDAAHTIHPLAGQGVNLGLLD 308
PRK07364 PRK07364
FAD-dependent hydroxylase;
229-330 2.10e-04

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 43.08  E-value: 2.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 229 EKVEAWSDERFWNELKRRLPEELSsKLvtghsleKSIAPLRSYVVEPMQ---Y--GRLFLVGDAAHIVPPTGAKGLNLAA 303
Cdd:PRK07364 247 KALLALPEAEFLAELQQRYGDQLG-KL-------ELLGDRFLFPVQLMQsdrYvqHRLALVGDAAHCCHPVGGQGLNLGI 318

                         90       100       110
                 ....*....|....*....|....*....|.
gi 515201464 304 SDVNYLWRILREYYHH----GRVDLLASYSR 330
Cdd:PRK07364 319 RDAAALAQVLQTAHQRgediGSLAVLKRYER 349
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 261-320 2.39e-04

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 42.82  E-value: 2.39e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515201464  261 LEKSIA--PLR-----SYVVEpmqygRLFLVGDAAHIVPPTGAKGLNLAASDVNYLWRILREYYHHG 320
Cdd:TIGR01989 313 VDKSRAafPLGlghadEYVTK-----RVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVG 374
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
233-306 4.48e-04

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 41.89  E-value: 4.48e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515201464 233 AWSDERFWNELKRRLPEELSSKLVTGhslEKSIAPL-----RSYVVEpmqygRLFLVGDAAHIVPPTGAKGLNLAASDV 306
Cdd:PRK07333 237 ALDDLVFEAELEQRFGHRLGELKVLG---KRRAFPLgltlaRSFVAP-----RFALVGDAAHGIHPIAGQGLNLGLKDV 307
PRK06753 PRK06753
hypothetical protein; Provisional
 1-344 8.55e-04

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 41.21  E-value: 8.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464   1 MKtqVAIIGAGPSGLLLGQLLHHAGIQTVILERQTPEYVLGrirAGILESGTV-ELLREAGAARRMEAEGLVHHGVEFLF 79
Cdd:PRK06753   1 MK--IAIIGAGIGGLTAAALLQEQGHEVKVFEKNESVKEVG---AGIGIGDNViKKLGNHDLAKGIKNAGQILSTMNLLD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464  80 EGKRVPVALTeLTAGkSVMVYGQTEVTRDLMaaRAECGAATIYGVSEVTINEAKSDRPSVSFiSNGEHCRLecDFIAGCD 159
Cdd:PRK06753  76 DKGTLLNKVK-LKSN-TLNVTLHRQTLIDII--KSYVKEDAIFTGKEVTKIENETDKVTIHF-ADGESEAF--DLCIGAD 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 160 GFHGVSRQSIPPGVLKEYEsvwpfG---WLGLLADtppvnpelIYAHHERGFvlcSQRSLTRSRYYLqVPLSEKVEAW-- 234
Cdd:PRK06753 149 GIHSKVRQSVNADSKVRYQ-----GytcFRGLIDD--------IDLKLPDCA---KEYWGTKGRFGI-VPLLNNQAYWfi 211

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 235 ------SDERFWNELKRRL-----------PEELSSKLVTG--HSLEKSIAPLRSYVvepmqYGRLFLVGDAAHIVPPTG 295
Cdd:PRK06753 212 tinakeRDPKYSSFGKPHLqayfnhypnevREILDKQSETGilHHDIYDLKPLKSFV-----YGRIVLLGDAAHATTPNM 286

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 515201464 296 AKGLNLAASDVNYLWRILREYYHHgrvDLLASYSRFALDRVWKGERFSW 344
Cdd:PRK06753 287 GQGAGQAMEDAIVLANCLNAYDFE---KALQRYDKIRVKHTAKVIKRSR 332
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
267-330 1.14e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 40.71  E-value: 1.14e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515201464 267 PLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYLWRILRE---YYHHGRVDLLASYSR 330
Cdd:PRK07608 268 PLRLQRVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLAGrepFRDLGDLRLLRRYER 334
PRK08132 PRK08132
FAD-dependent oxidoreductase; Provisional
 278-300 1.58e-03

FAD-dependent oxidoreductase; Provisional


Pssm-ID: 236158 [Multi-domain]  Cd Length: 547  Bit Score: 40.62  E-value: 1.58e-03
                         10        20
                 ....*....|....*....|...
gi 515201464 278 YGRLFLVGDAAHIVPPTGAKGLN 300
Cdd:PRK08132 298 HGRVLFAGDAAHQVSPFGARGAN 320
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 230-330 3.02e-03

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 39.37  E-value: 3.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 230 KVEAWSDERFWNELKRRLPEELSSKLVtghsLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAASDVNYL 309
Cdd:PRK08849 234 QLSAMNPEQLRSEILRHFPAELGEIKV----LQHGSFPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQGVNLGFKDVDVL 309

                         90       100
                 ....*....|....*....|...
gi 515201464 310 wriLREYYHHGRVD--LLASYSR 330
Cdd:PRK08849 310 ---LAETEKQGVLNdaSFARYER 329
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 229-335 9.18e-03

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 37.91  E-value: 9.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515201464 229 EKVEAWSDERFWNELKR----RLpeelsSKLVtgHSLEKSIAPLRSYVVEPMQYGRLFLVGDAAHIVPPTGAKGLNLAAS 304
Cdd:PRK05732 235 EEVLSWSDAQFLAELQQafgwRL-----GRIT--HAGKRSAYPLALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLR 307

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 515201464 305 DVNYLWRILREYYHH----GRVDLLASYS-RFALDR 335
Cdd:PRK05732 308 DVMSLAETLTQALARgediGDYAVLQRYQqRRQQDR 343
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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