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Conserved domains on  [gi|51513345|gb|AAH74918|]
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Keratin associated protein 9-3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Keratin_B2 super family cl37504
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 4-158 2.31e-12

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


The actual alignment was detected with superfamily member pfam01500:

Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 61.35  E-value: 2.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51513345     4 CCSPCCQPTCCRTTCWQPTtvttCSSTPCCQPSCCVSSCCQPCCHPtccqntCCRTTCCQPicvtSCCQPSCCSTPCCQP 83
Cdd:pfam01500  20 CGSGCCQPCCCQSSCCRPS----CCQTSCCQPTTFQSSCCRPTCQP------CCQTSCCQP----TCCQTSSCQTGCGGI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51513345    84 TCCGSSCGQSSSCAPVYCRRTCYHPTSVCLPGCLNQSCGSNCCQ------PCCRPACCETTCCrttcfQPTCVYSCCQPS 157
Cdd:pfam01500  86 GYGQEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQlhhaqaSCCRPSYCGQSCC-----RPACCCQCSEPT 160


                  .
gi 51513345   158 C 158
Cdd:pfam01500 161 C 161
 
Name Accession Description Interval E-value
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 4-158 2.31e-12

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 61.35  E-value: 2.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51513345     4 CCSPCCQPTCCRTTCWQPTtvttCSSTPCCQPSCCVSSCCQPCCHPtccqntCCRTTCCQPicvtSCCQPSCCSTPCCQP 83
Cdd:pfam01500  20 CGSGCCQPCCCQSSCCRPS----CCQTSCCQPTTFQSSCCRPTCQP------CCQTSCCQP----TCCQTSSCQTGCGGI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51513345    84 TCCGSSCGQSSSCAPVYCRRTCYHPTSVCLPGCLNQSCGSNCCQ------PCCRPACCETTCCrttcfQPTCVYSCCQPS 157
Cdd:pfam01500  86 GYGQEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQlhhaqaSCCRPSYCGQSCC-----RPACCCQCSEPT 160


                  .
gi 51513345   158 C 158
Cdd:pfam01500 161 C 161
NosR COG3901
Transcriptional regulator NosR of nitric oxide reductase [Transcription];
4-65 3.17e-03

Transcriptional regulator NosR of nitric oxide reductase [Transcription];


Pssm-ID: 443108 [Multi-domain]  Cd Length: 713  Bit Score: 36.84  E-value: 3.17e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 51513345   4 CCSPCCQPTCCRTTCWQPTTVTTCsstPCCqpsccvssCCQPCCHPTCCQNTCCRTTCCQPI 65
Cdd:COG3901 635 CCGCCCCCCKCCCIVIIIDGIIII---NEC--------CCCCCLCCRRCQDDPLCPPRIKKK 685
 
Name Accession Description Interval E-value
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 4-158 2.31e-12

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 61.35  E-value: 2.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51513345     4 CCSPCCQPTCCRTTCWQPTtvttCSSTPCCQPSCCVSSCCQPCCHPtccqntCCRTTCCQPicvtSCCQPSCCSTPCCQP 83
Cdd:pfam01500  20 CGSGCCQPCCCQSSCCRPS----CCQTSCCQPTTFQSSCCRPTCQP------CCQTSCCQP----TCCQTSSCQTGCGGI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51513345    84 TCCGSSCGQSSSCAPVYCRRTCYHPTSVCLPGCLNQSCGSNCCQ------PCCRPACCETTCCrttcfQPTCVYSCCQPS 157
Cdd:pfam01500  86 GYGQEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQlhhaqaSCCRPSYCGQSCC-----RPACCCQCSEPT 160


                  .
gi 51513345   158 C 158
Cdd:pfam01500 161 C 161
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
32-84 6.49e-09

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 49.30  E-value: 6.49e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 51513345    32 CCQPSCCVSSCCQPcchpTCCQNTCCRTTCCQPicvtSCCQPSCCSTPCCQPT 84
Cdd:pfam13885   1 CCQPSCCQPSCCQP----SCCQPSCCQPSCCQP----SCCRPSCCRSSCCQPT 45
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
27-70 3.00e-08

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 47.38  E-value: 3.00e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 51513345    27 CSSTPCCQPSCCVSSCCQP-CCHPTCCQNTCCRTTCCQPICVTSC 70
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPsCCQPSCCQPSCCRPSCCRSSCCQPT 45
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
8-65 8.15e-08

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 46.22  E-value: 8.15e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 51513345     8 CCQPTCCRTTCwqpttvttcsstpcCQPSCCVSSCCQP-CCHPTCCQNTCCRTTCCQPI 65
Cdd:pfam13885   1 CCQPSCCQPSC--------------CQPSCCQPSCCQPsCCQPSCCRPSCCRSSCCQPT 45
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
4-50 1.00e-05

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 40.83  E-value: 1.00e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 51513345     4 CCSPCCQPTCCRTTCWQPTtvttCSSTPCCQPSCCVSSCCQP-CCHPT 50
Cdd:pfam13885   2 CQPSCCQPSCCQPSCCQPS----CCQPSCCQPSCCRPSCCRSsCCQPT 45
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
51-109 2.01e-05

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 40.06  E-value: 2.01e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 51513345    51 CCQNTCCRTTCCQPicvtSCCQPSCCSTPCCQPTccgsscgqssSCAPVYCRRTCYHPT 109
Cdd:pfam13885   1 CCQPSCCQPSCCQP----SCCQPSCCQPSCCQPS----------CCRPSCCRSSCCQPT 45
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 2-56 4.63e-04

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 38.62  E-value: 4.63e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 51513345     2 THCCSPCCQPTCCRTTCWQPTTVttcsSTPCCQPSCCVSSCCQPCCHPTCCQNTC 56
Cdd:pfam01500 111 GTCLPPCCVVSCTPPTCCQLHHA----QASCCRPSYCGQSCCRPACCCQCSEPTC 161
NosR COG3901
Transcriptional regulator NosR of nitric oxide reductase [Transcription];
4-65 3.17e-03

Transcriptional regulator NosR of nitric oxide reductase [Transcription];


Pssm-ID: 443108 [Multi-domain]  Cd Length: 713  Bit Score: 36.84  E-value: 3.17e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 51513345   4 CCSPCCQPTCCRTTCWQPTTVTTCsstPCCqpsccvssCCQPCCHPTCCQNTCCRTTCCQPI 65
Cdd:COG3901 635 CCGCCCCCCKCCCIVIIIDGIIII---NEC--------CCCCCLCCRRCQDDPLCPPRIKKK 685
NosR COG3901
Transcriptional regulator NosR of nitric oxide reductase [Transcription];
13-83 4.88e-03

Transcriptional regulator NosR of nitric oxide reductase [Transcription];


Pssm-ID: 443108 [Multi-domain]  Cd Length: 713  Bit Score: 36.45  E-value: 4.88e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 51513345  13 CCRTTCWQpttvttCSSTPCCQPSCCVSSCCQPCCHPTCCQNTCCRTTCCQpicvtsCCQPSCCSTPCCQP 83
Cdd:COG3901 626 LWRRRRRE------CCCGCCCCCCKCCCIVIIIDGIIIINECCCCCCLCCR------RCQDDPLCPPRIKK 684
NosR COG3901
Transcriptional regulator NosR of nitric oxide reductase [Transcription];
32-84 8.02e-03

Transcriptional regulator NosR of nitric oxide reductase [Transcription];


Pssm-ID: 443108 [Multi-domain]  Cd Length: 713  Bit Score: 35.68  E-value: 8.02e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 51513345  32 CCQPSCCVSSCCQPCCHPTCCQNTCCRTTCCQPICVTSCCQPSCCSTPCCQPT 84
Cdd:COG3901 628 RRRRRECCCGCCCCCCKCCCIVIIIDGIIIINECCCCCCLCCRRCQDDPLCPP 680
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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