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Conserved domains on  [gi|514351530|gb|AGO49946|]
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Toll-like receptor 7, partial [Xenicus gilviventris]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
1-234 7.82e-18

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 82.67  E-value: 7.82e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   1 AFLELKKLTILSLKANNLTHIPPNLSS--TLKELYIYNNMIEVIEEhDLSALPNLEILDLSGNcprcynapypctpcpki 78
Cdd:COG4886  108 ELSNLTNLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN----------------- 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  79 SIEIHAKAFDSLKSLRILRLHSNSLRSIPSSwFKNIKNLKELDLSQNFLmKEIGDAqfLKLIPSLVELDLSFNfelkmys 158
Cdd:COG4886  170 QLTDLPEELGNLTNLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQL-TDLPEP--LANLTNLETLDLSNN------- 238

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 514351530 159 pflNLSE--TFASLS*LETLRLKGyvfkeLRARDLHPLLSLRNLTVLDLGTNFIKVADLTVFKEFPALKFIDLSVNKI 234
Cdd:COG4886  239 ---QLTDlpELGNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLL 308
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
1-234 7.82e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 82.67  E-value: 7.82e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   1 AFLELKKLTILSLKANNLTHIPPNLSS--TLKELYIYNNMIEVIEEhDLSALPNLEILDLSGNcprcynapypctpcpki 78
Cdd:COG4886  108 ELSNLTNLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN----------------- 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  79 SIEIHAKAFDSLKSLRILRLHSNSLRSIPSSwFKNIKNLKELDLSQNFLmKEIGDAqfLKLIPSLVELDLSFNfelkmys 158
Cdd:COG4886  170 QLTDLPEELGNLTNLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQL-TDLPEP--LANLTNLETLDLSNN------- 238

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 514351530 159 pflNLSE--TFASLS*LETLRLKGyvfkeLRARDLHPLLSLRNLTVLDLGTNFIKVADLTVFKEFPALKFIDLSVNKI 234
Cdd:COG4886  239 ---QLTDlpELGNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLL 308
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 6-151 5.42e-11

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 60.96  E-value: 5.42e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   6 KKLTILSLKANNLTHIPpNLSST--LKELYIYNNMIEVIEehDLSALPNLEILDLSGNCprcynapypctpcpkISI--- 80
Cdd:cd21340   24 KNLKVLYLYDNKITKIE-NLEFLtnLTHLYLQNNQIEKIE--NLENLVNLKKLYLGGNR---------------ISVveg 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  81 --------EIHAK----------AFDS------LKSLRILRLHSNSLRSIpsSWFKNIKNLKELDLSQNFL--MKEIgdA 134
Cdd:cd21340   86 lenltnleELHIEnqrlppgeklTFDPrslaalSNSLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQIsdLEEL--L 161

                        170
                 ....*....|....*..
gi 514351530 135 QFLKLIPSLVELDLSFN 151
Cdd:cd21340  162 DLLSSWPSLRELDLTGN 178
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 3-235 9.92e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 59.09  E-value: 9.92e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   3 LELKKLTILSLKANNLT-HIPPNLSS--TLKELYIYNNMIEVIEEHDLSALPNLEILDLSGNCprcYNAPYPCTPCPK-- 77
Cdd:PLN00113 305 IQLQNLEILHLFSNNFTgKIPVALTSlpRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNN---LTGEIPEGLCSSgn 381

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  78 ----------ISIEIhAKAFDSLKSLRILRLHSNSLRSIPSSWFKNIKNLKELDLSQNFLMKEIGDAQFlkLIPSLVELD 147
Cdd:PLN00113 382 lfklilfsnsLEGEI-PKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKW--DMPSLQMLS 458

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530 148 LSFN-FELKMYSPF-------LNLSE---------TFASLS*LETLRLKGyvfKELRARDLHPLLSLRNLTVLDLGTNFI 210
Cdd:PLN00113 459 LARNkFFGGLPDSFgskrlenLDLSRnqfsgavprKLGSLSELMQLKLSE---NKLSGEIPDELSSCKKLVSLDLSHNQL 535

                        250       260
                 ....*....|....*....|....*
gi 514351530 211 KVADLTVFKEFPALKFIDLSVNKIS 235
Cdd:PLN00113 536 SGQIPASFSEMPVLSQLDLSQNQLS 560
LRR_8 pfam13855
Leucine rich repeat;
92-151 1.45e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.22  E-value: 1.45e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   92 SLRILRLHSNSLRSIPSSWFKNIKNLKELDLSQNfLMKEIGDAQFLKLiPSLVELDLSFN 151
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNN-LLTTLSPGAFSGL-PSLRYLDLSGN 59
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
1-234 7.82e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 82.67  E-value: 7.82e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   1 AFLELKKLTILSLKANNLTHIPPNLSS--TLKELYIYNNMIEVIEEhDLSALPNLEILDLSGNcprcynapypctpcpki 78
Cdd:COG4886  108 ELSNLTNLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN----------------- 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  79 SIEIHAKAFDSLKSLRILRLHSNSLRSIPSSwFKNIKNLKELDLSQNFLmKEIGDAqfLKLIPSLVELDLSFNfelkmys 158
Cdd:COG4886  170 QLTDLPEELGNLTNLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQL-TDLPEP--LANLTNLETLDLSNN------- 238

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 514351530 159 pflNLSE--TFASLS*LETLRLKGyvfkeLRARDLHPLLSLRNLTVLDLGTNFIKVADLTVFKEFPALKFIDLSVNKI 234
Cdd:COG4886  239 ---QLTDlpELGNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLL 308
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
4-234 1.98e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 78.82  E-value: 1.98e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   4 ELKKLTILSLKANNLTHIPPNLSS--TLKELYIYNNMIEVIEEHdLSALPNLEILDLSGNcprcynapypctpcpkiSIE 81
Cdd:COG4886  134 NLTNLKELDLSNNQLTDLPEPLGNltNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNN-----------------QIT 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  82 IHAKAFDSLKSLRILRLHSNSLRSIPSSwFKNIKNLKELDLSQNflmkEIGDAQFLKLIPSLVELDLSFNfelkmysPFL 161
Cdd:COG4886  196 DLPEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNN----QLTDLPELGNLTNLEELDLSNN-------QLT 263

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 514351530 162 NLSETfASLS*LETLRLKGYVFKELRARDLHPLLSLRNLTVLDLGTNFIKVADLTVFKEFPALKFIDLSVNKI 234
Cdd:COG4886  264 DLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLV 335
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
3-235 3.35e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 69.19  E-value: 3.35e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   3 LELKKLTILSLKANNLTHIPPNLSSTLKELYIYNNMIEVIEEHDLSALPNLEILDLSGNCPRCYNAPYPCTPCPKISIEI 82
Cdd:COG4886   48 LLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTD 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  83 HAKAFDSLKSLRILRLHSNSLRSIPSSwFKNIKNLKELDLSQNFLmKEIGDAqfLKLIPSLVELDLSFNfelkmysPFLN 162
Cdd:COG4886  128 LPEELANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQL-TDLPEE--LGNLTNLKELDLSNN-------QITD 196

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 514351530 163 LSETFASLS*LETLRLKGYVFKELRArdlhPLLSLRNLTVLDLGTNfiKVADLTVFKEFPALKFIDLSVNKIS 235
Cdd:COG4886  197 LPEPLGNLTNLEELDLSGNQLTDLPE----PLANLTNLETLDLSNN--QLTDLPELGNLTNLEELDLSNNQLT 263
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 6-151 5.42e-11

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 60.96  E-value: 5.42e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   6 KKLTILSLKANNLTHIPpNLSST--LKELYIYNNMIEVIEehDLSALPNLEILDLSGNCprcynapypctpcpkISI--- 80
Cdd:cd21340   24 KNLKVLYLYDNKITKIE-NLEFLtnLTHLYLQNNQIEKIE--NLENLVNLKKLYLGGNR---------------ISVveg 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  81 --------EIHAK----------AFDS------LKSLRILRLHSNSLRSIpsSWFKNIKNLKELDLSQNFL--MKEIgdA 134
Cdd:cd21340   86 lenltnleELHIEnqrlppgeklTFDPrslaalSNSLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQIsdLEEL--L 161

                        170
                 ....*....|....*..
gi 514351530 135 QFLKLIPSLVELDLSFN 151
Cdd:cd21340  162 DLLSSWPSLRELDLTGN 178
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 5-235 5.08e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 58.26  E-value: 5.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   5 LKKLTILSLKANNLTHIPpNLSST--LKELYIYNNMIEVIEehDLSALPNLEILDLSGNCPRcynapypctpcpkiSIEi 82
Cdd:cd21340    1 LKRITHLYLNDKNITKID-NLSLCknLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIE--------------KIE- 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  83 hakAFDSLKSLRILRLHSNSLRSIpsSWFKNIKNLKELDLS-QNflmkeigdaqflklipslVELDLSFNFElkmyspfl 161
Cdd:cd21340   63 ---NLENLVNLKKLYLGGNRISVV--EGLENLTNLEELHIEnQR------------------LPPGEKLTFD-------- 111

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 514351530 162 nlSETFASLS*-LETLRLKGyvfkeLRARDLHPLLSLRNLTVLDLGTNFIK-VADLT-VFKEFPALKFIDLSVNKIS 235
Cdd:cd21340  112 --PRSLAALSNsLRVLNISG-----NNIDSLEPLAPLRNLEQLDASNNQISdLEELLdLLSSWPSLRELDLTGNPVC 181
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 3-235 9.92e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 59.09  E-value: 9.92e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   3 LELKKLTILSLKANNLT-HIPPNLSS--TLKELYIYNNMIEVIEEHDLSALPNLEILDLSGNCprcYNAPYPCTPCPK-- 77
Cdd:PLN00113 305 IQLQNLEILHLFSNNFTgKIPVALTSlpRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNN---LTGEIPEGLCSSgn 381

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  78 ----------ISIEIhAKAFDSLKSLRILRLHSNSLRSIPSSWFKNIKNLKELDLSQNFLMKEIGDAQFlkLIPSLVELD 147
Cdd:PLN00113 382 lfklilfsnsLEGEI-PKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKW--DMPSLQMLS 458

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530 148 LSFN-FELKMYSPF-------LNLSE---------TFASLS*LETLRLKGyvfKELRARDLHPLLSLRNLTVLDLGTNFI 210
Cdd:PLN00113 459 LARNkFFGGLPDSFgskrlenLDLSRnqfsgavprKLGSLSELMQLKLSE---NKLSGEIPDELSSCKKLVSLDLSHNQL 535

                        250       260
                 ....*....|....*....|....*
gi 514351530 211 KVADLTVFKEFPALKFIDLSVNKIS 235
Cdd:PLN00113 536 SGQIPASFSEMPVLSQLDLSQNQLS 560
LRR_8 pfam13855
Leucine rich repeat;
92-151 1.45e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.22  E-value: 1.45e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   92 SLRILRLHSNSLRSIPSSWFKNIKNLKELDLSQNfLMKEIGDAQFLKLiPSLVELDLSFN 151
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNN-LLTTLSPGAFSGL-PSLRYLDLSGN 59
LRR_8 pfam13855
Leucine rich repeat;
7-61 5.10e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.67  E-value: 5.10e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 514351530    7 KLTILSLKANNLTHIPP----NLSStLKELYIYNNMIEVIEEHDLSALPNLEILDLSGN 61
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDgafkGLSN-LKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
LRR_12 pfam18837
Leucine-rich repeat; This Pfam entry includes some LRRs that fail to be detected with the ...
 200-229 6.43e-08

Leucine-rich repeat; This Pfam entry includes some LRRs that fail to be detected with the pfam00560 model. This entry represents one repeat unit.


Pssm-ID: 408607  Cd Length: 30  Bit Score: 47.73  E-value: 6.43e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 514351530  200 LTVLDLGTNFIKVADLTVFKEFPALKFIDL 229
Cdd:pfam18837   1 LQTLHLQMNFINQAQLSIFGAFPGLRFVDL 30
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 1-235 8.37e-08

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 52.74  E-value: 8.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   1 AFLELKKLTILSLKANNLT----HIPPNL--SSTLKELYIYNNMIEV-IEEHDLSAL----PNLEILDLSGNcpRCYNAp 69
Cdd:cd00116   76 GLTKGCGLQELDLSDNALGpdgcGVLESLlrSSSLQELKLNNNGLGDrGLRLLAKGLkdlpPALEKLVLGRN--RLEGA- 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  70 ypctpcpkiSIEIHAKAFDSLKSLRILRLHSNSLRS--IPS--SWFKNIKNLKELDLSQNFLMkEIGDAQflklipslve 145
Cdd:cd00116  153 ---------SCEALAKALRANRDLKELNLANNGIGDagIRAlaEGLKANCNLEVLDLNNNGLT-DEGASA---------- 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530 146 ldlsfnfelkmyspflnLSETFASLS*LETLRLKGYVFKELRARDLHPLLSLRN--LTVLDLGTNFIK----VADLTVFK 219
Cdd:cd00116  213 -----------------LAETLASLKSLEVLNLGDNNLTDAGAAALASALLSPNisLLTLSLSCNDITddgaKDLAEVLA 275

                        250
                 ....*....|....*.
gi 514351530 220 EFPALKFIDLSVNKIS 235
Cdd:cd00116  276 EKESLLELDLRGNKFG 291
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 5-208 3.00e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 48.31  E-value: 3.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   5 LKKLTILSLKANNLT-HIPPNLSS--TLKELYI-YNNMIEVI--EEHDLSALPNLEIL--DLSGNCPrcynapypctpcp 76
Cdd:PLN00113 187 LTSLEFLTLASNQLVgQIPRELGQmkSLKWIYLgYNNLSGEIpyEIGGLTSLNHLDLVynNLTGPIP------------- 253

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  77 kisieihaKAFDSLKSLRILRLHSNSLR-SIPSSWFkNIKNLKELDLSQNFLMKEIGDaqflkLIPSLVELDLsfnfeLK 155
Cdd:PLN00113 254 --------SSLGNLKNLQYLFLYQNKLSgPIPPSIF-SLQKLISLDLSDNSLSGEIPE-----LVIQLQNLEI-----LH 314

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530 156 MYSPFLN--LSETFASLS*LETL-----RLKGYVFKELRARDlhpllslrNLTVLDLGTN 208
Cdd:PLN00113 315 LFSNNFTgkIPVALTSLPRLQVLqlwsnKFSGEIPKNLGKHN--------NLTVLDLSTN 366
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
6-127 1.75e-05

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 46.23  E-value: 1.75e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   6 KKLTILSLKANNLTHIPPNLSSTLKELYIYNNMIEVIEEhdlsALPN-LEILDLSGNcpRCYNAPYPcTPCPKISIEIHA 84
Cdd:PRK15370 199 EQITTLILDNNELKSLPENLQGNIKTLYANSNQLTSIPA----TLPDtIQEMELSIN--RITELPER-LPSALQSLDLFH 271

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 514351530  85 KAFDSL-----KSLRILRLHSNSLRSIPSSWFKNIKNLKELDLSQNFL 127
Cdd:PRK15370 272 NKISCLpenlpEELRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTAL 319
LRR_8 pfam13855
Leucine rich repeat;
51-125 2.05e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.36  E-value: 2.05e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 514351530   51 PNLEILDLSGNcprcynapypctpcpKISiEIHAKAFDSLKSLRILRLHSNSLRSIPSSWFKNIKNLKELDLSQN 125
Cdd:pfam13855   1 PNLRSLDLSNN---------------RLT-SLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
22-235 3.22e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 44.92  E-value: 3.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  22 PPNLSSTLKELYIYNNMIEVIEEHDLSALPNLEILDLSGNCPRCYNAPYPCTPCPKISIEIHAKAFDSLKSLRILRLHSN 101
Cdd:COG4886    3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530 102 SLRSIPSSWFKNIKNLKELDLSQNFLMKEIGDAQFLKL--------------IPSLVELDLSFNfelkmysPFLNLSETF 167
Cdd:COG4886   83 SLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLsgnqltdlpeelanLTNLKELDLSNN-------QLTDLPEPL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 514351530 168 ASLS*LETLRLKGYVFKELRArdlhPLLSLRNLTVLDLGTNFIKvaDL-TVFKEFPALKFIDLSVNKIS 235
Cdd:COG4886  156 GNLTNLKSLDLSNNQLTDLPE----ELGNLTNLKELDLSNNQIT--DLpEPLGNLTNLEELDLSGNQLT 218
LRR_8 pfam13855
Leucine rich repeat;
27-103 3.26e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 3.26e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 514351530   27 STLKELYIYNNMIEVIEEHDLSALPNLEILDLSGNCprcynapypctpcpkISIeIHAKAFDSLKSLRILRLHSNSL 103
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNL---------------LTT-LSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 4-151 1.87e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.91  E-value: 1.87e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   4 ELKKLTILSLKANNLTHIPPNL--SSTLKELYIYNNMIEVIEEHDLSALPNLEILDLSGNcprcynapypctpcpKISIE 81
Cdd:PLN00113 450 DMPSLQMLSLARNKFFGGLPDSfgSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSEN---------------KLSGE 514

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 514351530  82 IhAKAFDSLKSLRILRLHSNSLR-SIPSSwFKNIKNLKELDLSQNFLMKEIgdAQFLKLIPSLVELDLSFN 151
Cdd:PLN00113 515 I-PDELSSCKKLVSLDLSHNQLSgQIPAS-FSEMPVLSQLDLSQNQLSGEI--PKNLGNVESLVQVNISHN 581
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 8-256 2.18e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.53  E-value: 2.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   8 LTILSLKANNLT-HIPPNLSSTLKELYIYNNMIEVIEEHDLSALPNLEILDLSGNcprcynapypcTPCPKISIEIhaka 86
Cdd:PLN00113 120 LRYLNLSNNNFTgSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGN-----------VLVGKIPNSL---- 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  87 fDSLKSLRILRLHSNSLRSIPSSWFKNIKNLKELDLSQNFLMKEIgDAQFLKLIpSLVELDLSFNfelkmyspflNLS-- 164
Cdd:PLN00113 185 -TNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEI-PYEIGGLT-SLNHLDLVYN----------NLTgp 251

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530 165 --ETFASLS*LETLrlkgYVFKELRARDLHP-LLSLRNLTVLDLGTNFIKVADLTVFKEFPALKFIDLSVNKISPSSGEs 241
Cdd:PLN00113 252 ipSSLGNLKNLQYL----FLYQNKLSGPIPPsIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPV- 326

                        250
                 ....*....|....*
gi 514351530 242 nfdGFCSNPRISVEQ 256
Cdd:PLN00113 327 ---ALTSLPRLQVLQ 338
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
8-128 2.75e-04

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 42.38  E-value: 2.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   8 LTILSLKANNLTHIPPNLSSTLKELYIYNNMIEVIEEhdlSALPNLEILDLSGNCPRCYNAPYPctpcpkisieihakaf 87
Cdd:PRK15370 285 LRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPE---TLPPGLKTLEAGENALTSLPASLP---------------- 345

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 514351530  88 dslKSLRILRLHSNSLRSIPSSWfknIKNLKELDLSQNFLM 128
Cdd:PRK15370 346 ---PELQVLDVSKNQITVLPETL---PPTITTLDVSRNALT 380
PLN03150 PLN03150
hypothetical protein; Provisional
 86-192 6.94e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 40.95  E-value: 6.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  86 AFDSLKSLRI---LRLHSNSLRS-IPSSWFKnIKNLKELDLSQNFLMKEIGDAqfLKLIPSLVELDLSFNfelkmyspFL 161
Cdd:PLN03150 410 QFDSTKGKWFidgLGLDNQGLRGfIPNDISK-LRHLQSINLSGNSIRGNIPPS--LGSITSLEVLDLSYN--------SF 478

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 514351530 162 NLS--ETFASLS*LETL-----RLKGYVFKELRARDLH 192
Cdd:PLN03150 479 NGSipESLGQLTSLRILnlngnSLSGRVPAALGGRLLH 516
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 4-235 1.81e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.83  E-value: 1.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530   4 ELKKLTILSLKANNLT-HIPPNLS--STLKELYIYNNMIEVIEEHDLSALPNLEILDLSGNCprcYNAPYPCTPCPKISI 80
Cdd:PLN00113 234 GLTSLNHLDLVYNNLTgPIPSSLGnlKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNS---LSGEIPELVIQLQNL 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530  81 EI-H----------AKAFDSLKSLRILRLHSNSLR-SIPSSWFKNiKNLKELDLSQNFLMKEIGDAqflklipslveLDL 148
Cdd:PLN00113 311 EIlHlfsnnftgkiPVALTSLPRLQVLQLWSNKFSgEIPKNLGKH-NNLTVLDLSTNNLTGEIPEG-----------LCS 378

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514351530 149 SFN-FELKMYSPFLN--LSETFASLS*LETLRLKGYVFKELRARDlhpLLSLRNLTVLDLGTNFIKVADLTVFKEFPALK 225
Cdd:PLN00113 379 SGNlFKLILFSNSLEgeIPKSLGACRSLRRVRLQDNSFSGELPSE---FTKLPLVYFLDISNNNLQGRINSRKWDMPSLQ 455

                        250
                 ....*....|
gi 514351530 226 FIDLSVNKIS 235
Cdd:PLN00113 456 MLSLARNKFF 465
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 91-133 2.39e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 35.30  E-value: 2.39e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 514351530   91 KSLRILRLHSNSLRSIPSswFKNIKNLKELDLSQNFLMKEIGD 133
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPP--LAKLPNLETLDLSGNNKITDLSD 41
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 29-61 3.14e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 34.91  E-value: 3.14e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 514351530   29 LKELYIYNNMIEVIEEhdLSALPNLEILDLSGN 61
Cdd:pfam12799   3 LEVLDLSNNQITDIPP--LAKLPNLETLDLSGN 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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